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Rudiger Woscholski - Publications

Affiliations: 
Institute of Chemical Biology Imperial College London, London, England, United Kingdom 
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37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Reeh K, Summers PA, Gould IR, Woscholski R, Vilar R. Design, synthesis and evaluation of a tripodal receptor for phosphatidylinositol phosphates. Scientific Reports. 10: 18450. PMID 33116198 DOI: 10.1038/s41598-020-75484-w  0.55
2017 Cilibrizzi A, Fedorova M, Collins J, Leatherbarrow R, Woscholski R, Vilar R. A tri-functional vanadium(iv) complex to detect cysteine oxidation. Dalton Transactions (Cambridge, England : 2003). PMID 28513686 DOI: 10.1039/C7Dt00076F  0.709
2017 Cilibrizzi A, Terenghi M, Fedorova M, Woscholski R, Klug D, Vilar R. Small-molecule optical probes for cell imaging of protein sulfenylation and their application to monitor cisplatin induced protein oxidation Sensors and Actuators B: Chemical. 248: 437-446. DOI: 10.1016/J.Snb.2017.03.171  0.705
2016 Wilson N, Mak LH, Cilibrizzi A, Gee AD, Long NJ, Woscholski R, Vilar R. A lipophilic copper(ii) complex as an optical probe for intracellular detection of NO. Dalton Transactions (Cambridge, England : 2003). PMID 27792231 DOI: 10.1039/C6Dt02880B  0.699
2016 Collins J, Cilibrizzi A, Fedorova M, Whyte G, Mak LH, Guterman I, Leatherbarrow R, Woscholski R, Vilar R. Vanadyl complexes with dansyl-labelled di-picolinic acid ligands: synthesis, phosphatase inhibition activity and cellular uptake studies. Dalton Transactions (Cambridge, England : 2003). 45: 7104-13. PMID 27008377 DOI: 10.1039/C5Dt04753F  0.703
2016 Verrastro I, Tveen-Jensen K, Woscholski R, Spickett CM, Pitt AR. Reversible oxidation of phosphatase and tensin homolog (PTEN) alters its interactions with signaling and regulatory proteins. Free Radical Biology & Medicine. 90: 24-34. PMID 26561776 DOI: 10.1016/J.Freeradbiomed.2015.11.004  0.387
2015 Billcliff PG, Noakes CJ, Mehta ZB, Yan G, Mak L, Woscholski R, Lowe M. OCRL1 engages with the F-BAR protein pacsin 2 to promote biogenesis of membrane trafficking intermediates. Molecular Biology of the Cell. PMID 26510499 DOI: 10.1091/Mbc.E15-06-0329  0.3
2015 Mak LH, Woscholski R. Targeting PTEN using small molecule inhibitors. Methods (San Diego, Calif.). 77: 63-8. PMID 25747336 DOI: 10.1016/J.Ymeth.2015.02.007  0.378
2015 Furse S, Mak L, Tate EW, Templer RH, Ces O, Woscholski R, Gaffney PR. Synthesis of unsaturated phosphatidylinositol 4-phosphates and the effects of substrate unsaturation on SopB phosphatase activity. Organic & Biomolecular Chemistry. 13: 2001-11. PMID 25515724 DOI: 10.1039/C4Ob02258K  0.352
2015 Amor B, Yaliraki SN, Woscholski R, Barahona M. Uncovering allosteric pathways in caspase-1 using Markov transient analysis and multiscale community detection. Molecular Biosystems. 10: 2247-58. PMID 24947802 DOI: 10.1039/C4Mb00088A  0.306
2014 Murray JI, Woscholski R, Spivey AC. Highly efficient and selective phosphorylation of amino acid derivatives and polyols catalysed by 2-aryl-4-(dimethylamino)pyridine-N-oxides--towards kinase-like reactivity. Chemical Communications (Cambridge, England). 50: 13608-11. PMID 25248055 DOI: 10.1039/C4Cc05388E  0.351
2014 Pulido R, Baker SJ, Barata JT, Carracedo A, Cid VJ, Chin-Sang ID, Davé V, den Hertog J, Devreotes P, Eickholt BJ, Eng C, Furnari FB, Georgescu MM, Gericke A, Hopkins B, ... ... Woscholski R, et al. A unified nomenclature and amino acid numbering for human PTEN. Science Signaling. 7: pe15. PMID 24985344 DOI: 10.1126/Scisignal.2005560  0.31
2013 Murray JI, Spivey AC, Woscholski R. Alternative synthetic tools to phospho-specific antibodies for phosphoproteome analysis: progress and prospects. Journal of Chemical Biology. 6: 175-84. PMID 24432133 DOI: 10.1007/S12154-013-0100-Y  0.313
2013 Whyte GF, Vilar R, Woscholski R. Molecular recognition with boronic acids-applications in chemical biology. Journal of Chemical Biology. 6: 161-74. PMID 24432132 DOI: 10.1007/S12154-013-0099-0  0.583
2013 Miller D, Booth PJ, Seddon JM, Templer RH, Law RV, Woscholski R, Ces O, Barter LM. Protocell design through modular compartmentalization. Journal of the Royal Society, Interface / the Royal Society. 10: 20130496. PMID 23925982 DOI: 10.1098/Rsif.2013.0496  0.306
2012 Domart MC, Hobday TM, Peddie CJ, Chung GH, Wang A, Yeh K, Jethwa N, Zhang Q, Wakelam MJ, Woscholski R, Byrne RD, Collinson LM, Poccia DL, Larijani B. Acute manipulation of diacylglycerol reveals roles in nuclear envelope assembly & endoplasmic reticulum morphology. Plos One. 7: e51150. PMID 23227247 DOI: 10.1371/Journal.Pone.0051150  0.307
2012 Mak LH, Knott J, Scott KA, Scott C, Whyte GF, Ye Y, Mann DJ, Ces O, Stivers J, Woscholski R. Arylstibonic acids are potent and isoform-selective inhibitors of Cdc25a and Cdc25b phosphatases. Bioorganic & Medicinal Chemistry. 20: 4371-6. PMID 22705189 DOI: 10.1016/J.Bmc.2012.05.040  0.38
2012 Charalambous K, Booth PJ, Woscholski R, Seddon JM, Templer RH, Law RV, Barter LM, Ces O. Engineering de novo membrane-mediated protein-protein communication networks. Journal of the American Chemical Society. 134: 5746-9. PMID 22428921 DOI: 10.1021/Ja300523Q  0.302
2011 Mak LH, Georgiades SN, Rosivatz E, Whyte GF, Mirabelli M, Vilar R, Woscholski R. A small molecule mimicking a phosphatidylinositol (4,5)-bisphosphate binding pleckstrin homology domain. Acs Chemical Biology. 6: 1382-90. PMID 21958214 DOI: 10.1021/Cb2003187  0.568
2011 Georgiades SN, Mak LH, Angurell I, Rosivatz E, Firouz Mohd Mustapa M, Polychroni C, Woscholski R, Vilar R. Identification of a potent activator of Akt phosphorylation from a novel series of phenolic, picolinic, pyridino, and hydroxamic zinc(II) complexes. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 16: 195-208. PMID 20972690 DOI: 10.1007/S00775-010-0716-0  0.617
2010 Mak LH, Vilar R, Woscholski R. Characterisation of the PTEN inhibitor VO-OHpic. Journal of Chemical Biology. 3: 157-63. PMID 21643420 DOI: 10.1007/S12154-010-0041-7  0.559
2010 Smith ME, Gunn RM, Rosivatz E, Mak LH, Woscholski R, Hailes HC. Development of chemical probes: toward the mode of action of a methylene-linked di(aryl acetate) E1. Bioorganic & Medicinal Chemistry. 18: 4917-27. PMID 20591679 DOI: 10.1016/J.Bmc.2010.06.017  0.335
2009 Ho KK, Rosivatz E, Gunn RM, Smith ME, Stavropoulou AV, Rosivatz E, Numbere MG, Wong JB, Lafitte VG, Behrendt JM, Myatt SS, Hailes HC, Woscholski R, Lam EW. The novel molecule 2-[5-(2-chloroethyl)-2-acetoxy-benzyl]-4-(2-chloroethyl)-phenyl acetate inhibits phosphoinositide 3-kinase/Akt/mammalian target of rapamycin signalling through JNK activation in cancer cells. The Febs Journal. 276: 4037-50. PMID 19549188 DOI: 10.1111/J.1742-4658.2009.07112.X  0.355
2009 Rosivatz E, Woscholski R. Measurement of PTEN activity in vivo by imaging phosphorylated Akt. Methods in Molecular Biology (Clifton, N.J.). 462: 213-22. PMID 19160672 DOI: 10.1007/978-1-60327-115-8_14  0.341
2009 Mulet X, Rosivatz E, Ho KK, Gauthé BL, Ces O, Templer RH, Woscholski R. Spatial localization of PtdInsP2 in phase-separated giant unilamellar vesicles with a fluorescent PLC-delta 1 PH domain. Methods in Molecular Biology (Clifton, N.J.). 462: 135-44. PMID 19160665 DOI: 10.1007/978-1-60327-115-8_8  0.311
2007 Byrne RD, Rosivatz E, Parsons M, Larijani B, Parker PJ, Ng T, Woscholski R. Differential activation of the PI 3-kinase effectors AKT/PKB and p70 S6 kinase by compound 48/80 is mediated by PKCalpha. Cellular Signalling. 19: 321-9. PMID 16942862 DOI: 10.1016/J.Cellsig.2006.07.004  0.359
2006 Rosivatz E, Matthews JG, McDonald NQ, Mulet X, Ho KK, Lossi N, Schmid AC, Mirabelli M, Pomeranz KM, Erneux C, Lam EWF, Vilar R, Woscholski R. A small molecule inhibitor for phosphatase and tensin homologue deleted on chromosome 10 (PTEN). Acs Chemical Biology. 1: 780-790. PMID 17240976 DOI: 10.1021/Cb600352F  0.616
2006 Fili N, Calleja V, Woscholski R, Parker PJ, Larijani B. Compartmental signal modulation: Endosomal phosphatidylinositol 3-phosphate controls endosome morphology and selective cargo sorting. Proceedings of the National Academy of Sciences of the United States of America. 103: 15473-15478. PMID 17030795 DOI: 10.1073/Pnas.0607040103  0.324
2004 Schmid AC, Wise HM, Mitchell CA, Nussbaum R, Woscholski R. Type II phosphoinositide 5-phosphatases have unique sensitivities towards fatty acid composition and head group phosphorylation. Febs Letters. 576: 9-13. PMID 15474001 DOI: 10.1016/J.Febslet.2004.08.052  0.337
2004 Schmid AC, Byrne RD, Vilar R, Woscholski R. Bisperoxovanadium compounds are potent PTEN inhibitors. Febs Letters. 566: 35-8. PMID 15147864 DOI: 10.1016/J.Febslet.2004.03.102  0.591
2004 Schmid AC, Woscholski R. Phosphatases as small-molecule targets: inhibiting the endogenous inhibitors of kinases. Biochemical Society Transactions. 32: 348-9. PMID 15046606 DOI: 10.1042/Bst0320348  0.386
2003 Calleja V, Ameer-Beg SM, Vojnovic B, Woscholski R, Downward J, Larijani B. Monitoring conformational changes of proteins in cells by fluorescence lifetime imaging microscopy. The Biochemical Journal. 372: 33-40. PMID 12662152 DOI: 10.1042/Bj20030358  0.387
2000 Hughes WE, Woscholski R, Cooke FT, Patrick RS, Dove SK, McDonald NQ, Parker PJ. SAC1 encodes a regulated lipid phosphoinositide phosphatase, defects in which can be suppressed by the homologous Inp52p and Inp53p phosphatases Journal of Biological Chemistry. 275: 801-808. PMID 10625610 DOI: 10.1074/Jbc.275.2.801  0.337
2000 GIURIATO S, BODIN S, ERNEUX C, WOSCHOLSKI R, PLANTAVID M, CHAP H, PAYRASTRE B. pp60c-src associates with the SH2-containing inositol-5-phosphatase SHIP1 and is involved in its tyrosine phosphorylation downstream of αIIbβ3 integrin in human platelets Biochemical Journal. 348: 107-112. DOI: 10.1042/Bj3480107  0.349
1998 Pesesse X, Moreau C, Drayer AL, Woscholski R, Parker P, Erneux C. The SH2 domain containing inositol 5-phosphatase SHIP2 displays phosphatidylinositol 3,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate 5-phosphatase activity Febs Letters. 437: 301-303. PMID 9824312 DOI: 10.1016/S0014-5793(98)01255-1  0.329
1995 Petritsch C, Woscholski R, Edelmann HML, Parker PJ, Ballou LM. Selective Inhibition of p70 S6 Kinase Activation by Phosphatidylinositol 3‐Kinase Inhibitors Febs Journal. 230: 431-438. PMID 7607212 DOI: 10.1111/J.1432-1033.1995.0431H.X  0.356
1994 Kodaki T, Woscholski R, Emr S, Waterfield MD, Nurse P, Parker PJ. Mammalian phosphatidylinositol 3'-kinase induces a lethal phenotype on expression in Schizosaccharomyces pombe; comparison with the VPS34 gene product. European Journal of Biochemistry. 219: 775-80. PMID 8112328 DOI: 10.1111/J.1432-1033.1994.Tb18557.X  0.348
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