| Year |
Citation |
Score |
| 2022 |
Ortega-Gonzalez P, Taylor G, Jangra RK, Tenorio R, Fernandez de Castro I, Mainou BA, Orchard RC, Wilen CB, Brigleb PH, Sojati J, Chandran K, Sachse M, Risco C, Dermody TS. Reovirus infection is regulated by NPC1 and endosomal cholesterol homeostasis. Plos Pathogens. 18: e1010322. PMID 35263388 DOI: 10.1371/journal.ppat.1010322 |
0.304 |
|
| 2021 |
Li T, Li Z, Deans EE, Mittler E, Liu M, Chandran K, Ivanovic T. The shape of pleomorphic virions determines resistance to cell-entry pressure. Nature Microbiology. PMID 33737748 DOI: 10.1038/s41564-021-00877-0 |
0.755 |
|
| 2020 |
Serris A, Stass R, Bignon EA, Muena NA, Manuguerra JC, Jangra RK, Li S, Chandran K, Tischler ND, Huiskonen JT, Rey FA, Guardado-Calvo P. The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism. Cell. PMID 32937107 DOI: 10.1016/J.Cell.2020.08.023 |
0.384 |
|
| 2020 |
Jia M, Liberatore RA, Guo Y, Chan KW, Pan R, Lu H, Waltari E, Mittler E, Chandran K, Finzi A, Kaufmann DE, Seaman MS, Ho DD, Shapiro L, Sheng Z, et al. VSV-Displayed HIV-1 Envelope Identifies Broadly Neutralizing Antibodies Class-Switched to IgG and IgA. Cell Host & Microbe. PMID 32315598 DOI: 10.1016/J.Chom.2020.03.024 |
0.316 |
|
| 2020 |
Wu X, Spence JS, Das T, Yuan X, Chen C, Zhang Y, Li Y, Sun Y, Chandran K, Hang HC, Peng T. Site-Specific Photo-Crosslinking Proteomics Reveal Regulation of IFITM3 Trafficking and Turnover by VCP/p97 ATPase. Cell Chemical Biology. PMID 32243810 DOI: 10.1016/J.Chembiol.2020.03.004 |
0.4 |
|
| 2020 |
Das DK, Bulow U, Diehl WE, Durham ND, Senjobe F, Chandran K, Luban J, Munro JB. Conformational changes in the Ebola virus membrane fusion machine induced by pH, Ca2+, and receptor binding. Plos Biology. 18: e3000626. PMID 32040508 DOI: 10.1371/Journal.Pbio.3000626 |
0.347 |
|
| 2020 |
Herbert AS, Froude JW, Ortiz RA, Kuehne AI, Dorosky DE, Bakken RR, Zak SE, Josleyn NM, Musiychuk K, Jones RM, Green B, Streatfield SJ, Wec AZ, Bohorova N, Bohorov O, ... ... Chandran K, et al. Development of an antibody cocktail for treatment of Sudan virus infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 32015126 DOI: 10.1073/Pnas.1914985117 |
0.309 |
|
| 2020 |
Mishra AK, Moyer CL, Abelson DM, Deer DJ, El Omari K, Duman R, Lobel L, Lutwama JJ, Dye JM, Wagner A, Chandran K, Cross RW, Geisbert TW, Zeitlin L, Bornholdt ZA, et al. Structure and Characterization of Crimean-Congo Hemorrhagic Fever Virus GP38. Journal of Virology. PMID 31996434 DOI: 10.1128/Jvi.02005-19 |
0.343 |
|
| 2020 |
Durham ND, Howard AR, Govindan R, Senjobe F, Fels JM, Diehl WE, Luban J, Chandran K, Munro JB. Real-Time Analysis of Individual Ebola Virus Glycoproteins Reveals Pre-Fusion, Entry-Relevant Conformational Dynamics. Viruses. 12. PMID 31952255 DOI: 10.3390/V12010103 |
0.384 |
|
| 2019 |
Mittler E, Dieterle ME, Kleinfelter LM, Slough MM, Chandran K, Jangra RK. Hantavirus entry: Perspectives and recent advances. Advances in Virus Research. 104: 185-224. PMID 31439149 DOI: 10.1016/Bs.Aivir.2019.07.002 |
0.427 |
|
| 2019 |
Fels JM, Spence JS, Bortz RH, Bornholdt ZA, Chandran K. A Hyperstabilizing Mutation in the Base of the Ebola Virus Glycoprotein Acts at Multiple Steps To Abrogate Viral Entry. Mbio. 10. PMID 31289183 DOI: 10.1128/Mbio.01408-19 |
0.398 |
|
| 2019 |
Kuhn JH, Amarasinghe GK, Basler CF, Bavari S, Bukreyev A, Chandran K, Crozier I, Dolnik O, Dye JM, Formenty PBH, Griffiths A, Hewson R, Kobinger GP, Leroy EM, Mühlberger E, et al. ICTV Virus Taxonomy Profile: Filoviridae. The Journal of General Virology. PMID 31021739 DOI: 10.1099/Jgv.0.001252 |
0.331 |
|
| 2019 |
West BR, Wec AZ, Moyer CL, Fusco ML, Ilinykh PA, Huang K, Wirchnianski AS, James RM, Herbert AS, Hui S, Goodwin E, Howell KA, Kailasan S, Aman MJ, Walker LM, ... ... Chandran K, et al. Structural basis of broad ebolavirus neutralization by a human survivor antibody. Nature Structural & Molecular Biology. PMID 30833785 DOI: 10.1038/S41594-019-0191-4 |
0.334 |
|
| 2019 |
Spence JS, He R, Hoffmann HH, Das T, Thinon E, Rice CM, Peng T, Chandran K, Hang HC. IFITM3 directly engages and shuttles incoming virus particles to lysosomes. Nature Chemical Biology. PMID 30643282 DOI: 10.1038/S41589-018-0213-2 |
0.428 |
|
| 2019 |
Bornholdt ZA, Herbert AS, Mire CE, He S, Cross RW, Wec AZ, Abelson DM, Geisbert JB, James RM, Rahim MN, Zhu W, Borisevich V, Banadyga L, Gunn BM, Agans KN, ... ... Chandran K, et al. A Two-Antibody Pan-Ebolavirus Cocktail Confers Broad Therapeutic Protection in Ferrets and Nonhuman Primates. Cell Host & Microbe. 25: 49-58.e5. PMID 30629918 DOI: 10.1016/J.Chom.2018.12.005 |
0.349 |
|
| 2019 |
Goldstein T, Anthony S, Gbakima A, Bird B, Bangura J, Tremeau-Bravard A, Belaganahalli M, Wells H, Dhanota J, Liang E, Grodus M, Jangra R, Dejesus V, Lasso G, Smith B, ... ... Chandran K, et al. The discovery of a new Ebolavirus, Bombali virus, adds further support for bats as hosts of Ebolaviruses International Journal of Infectious Diseases. 79: 4-5. DOI: 10.1016/J.Ijid.2018.11.030 |
0.314 |
|
| 2018 |
Fedewa G, Radoshitzky SR, Chī X, Dǒng L, Zeng X, Spear M, Strauli N, Ng M, Chandran K, Stenglein MD, Hernandez RD, Jahrling PB, Kuhn JH, DeRisi JL. Ebola virus, but not Marburg virus, replicates efficiently and without required adaptation in snake cells. Virus Evolution. 4: vey034. PMID 30524754 DOI: 10.1093/Ve/Vey034 |
0.361 |
|
| 2018 |
Jangra RK, Herbert AS, Li R, Jae LT, Kleinfelter LM, Slough MM, Barker SL, Guardado-Calvo P, Román-Sosa G, Dieterle ME, Kuehne AI, Muena NA, Wirchnianski AS, Nyakatura EK, Fels JM, ... ... Chandran K, et al. Protocadherin-1 is essential for cell entry by New World hantaviruses. Nature. 563: 559-563. PMID 30464266 DOI: 10.1038/S41586-018-0702-1 |
0.324 |
|
| 2018 |
Goldstein T, Anthony SJ, Gbakima A, Bird BH, Bangura J, Tremeau-Bravard A, Belaganahalli MN, Wells HL, Dhanota JK, Liang E, Grodus M, Jangra RK, DeJesus VA, Lasso G, Smith BR, ... ... Chandran K, et al. The discovery of Bombali virus adds further support for bats as hosts of ebolaviruses. Nature Microbiology. PMID 30150734 DOI: 10.1038/S41564-018-0227-2 |
0.335 |
|
| 2018 |
Saphire EO, Schendel SL, Fusco ML, Gangavarapu K, Gunn BM, Wec AZ, Halfmann PJ, Brannan JM, Herbert AS, Qiu X, Wagh K, He S, Giorgi EE, Theiler J, Pommert KBJ, ... ... Chandran K, et al. Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection. Cell. 174: 938-952.e13. PMID 30096313 DOI: 10.1016/J.Cell.2018.07.033 |
0.348 |
|
| 2018 |
Gunn BM, Yu WH, Karim MM, Brannan JM, Herbert AS, Wec AZ, Halfmann PJ, Fusco ML, Schendel SL, Gangavarapu K, Krause T, Qiu X, He S, Das J, Suscovich TJ, ... ... Chandran K, et al. A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus. Cell Host & Microbe. 24: 221-233.e5. PMID 30092199 DOI: 10.1016/J.Chom.2018.07.009 |
0.319 |
|
| 2018 |
Gizzi AS, Grove TL, Arnold JJ, Jose J, Jangra RK, Garforth SJ, Du Q, Cahill SM, Dulyaninova NG, Love JD, Chandran K, Bresnick AR, Cameron CE, Almo SC. A naturally occurring antiviral ribonucleotide encoded by the human genome. Nature. PMID 29925952 DOI: 10.1038/S41586-018-0238-4 |
0.385 |
|
| 2018 |
Nyakatura EK, Zak SE, Wec AZ, Hofmann D, Shulenin S, Bakken RR, Aman MJ, Chandran K, Dye JM, Lai JR. Design and evaluation of bi- and trispecific antibodies targeting multiple filovirus glycoproteins. The Journal of Biological Chemistry. PMID 29500195 DOI: 10.1074/Jbc.Ra117.001627 |
0.338 |
|
| 2017 |
Hofmann D, Zak SE, Nyakatura EK, Mittler E, Bakken RR, Chandran K, Dye JM, Lai JR. Mechanistic and Fc Requirements for Inhibition of Sudan Virus Entry and In Vivo Protection by a Synthetic Antibody. Immunology Letters. PMID 28890093 DOI: 10.1016/J.Imlet.2017.09.002 |
0.409 |
|
| 2017 |
Davey RA, Shtanko O, Anantpadma M, Sakurai Y, Chandran K, Maury W. Mechanisms of Filovirus Entry Current Topics in Microbiology and Immunology. 411: 323-352. PMID 28601947 DOI: 10.1007/82_2017_14 |
0.352 |
|
| 2017 |
Hastie KM, Zandonatti MA, Kleinfelter LM, Heinrich ML, Rowland MM, Chandran K, Branco LM, Robinson JE, Garry RF, Saphire EO. Structural basis for antibody-mediated neutralization of Lassa virus. Science (New York, N.Y.). 356: 923-928. PMID 28572385 DOI: 10.1126/Science.Aam7260 |
0.338 |
|
| 2017 |
Wec AZ, Herbert AS, Murin CD, Nyakatura EK, Abelson DM, Fels JM, He S, James RM, de La Vega MA, Zhu W, Bakken RR, Goodwin E, Turner HL, Jangra RK, Zeitlin L, ... ... Chandran K, et al. Antibodies from a Human Survivor Define Sites of Vulnerability for Broad Protection against Ebolaviruses. Cell. 169: 878-890.e15. PMID 28525755 DOI: 10.1016/J.Cell.2017.04.037 |
0.37 |
|
| 2017 |
Froude JW, Pelat T, Miethe S, Zak SE, Wec AZ, Chandran K, Brannan JM, Bakken RR, Hust M, Thullier P, Dye JM. Generation and characterization of protective antibodies to Marburg virus. Mabs. 0. PMID 28287337 DOI: 10.1080/19420862.2017.1299848 |
0.347 |
|
| 2017 |
Liang J, Jangra RK, Bollinger L, Wada J, Radoshitzky SR, Chandran K, Jahrling PB, Kuhn JH, Jensen KS. Candidate medical countermeasures targeting Ebola virus cell entry Future Virology. 12: 119-140. DOI: 10.2217/Fvl-2016-0113 |
0.358 |
|
| 2016 |
Wec AZ, Nyakatura EK, Herbert AS, Howell KA, Holtsberg FW, Bakken RR, Mittler E, Christin JR, Shulenin S, Jangra RK, Bharrhan S, Kuehne AI, Bornholdt ZA, Flyak AI, Saphire EO, ... ... Chandran K, et al. A "Trojan horse" bispecific antibody strategy for broad protection against ebolaviruses. Science (New York, N.Y.). PMID 27608667 DOI: 10.1126/Science.Aag3267 |
0.324 |
|
| 2016 |
van der Linden WA, Schulze CJ, Herbert AS, Krause TB, Wirchnianski AA, Dye JM, Chandran K, Bogyo M. Cysteine Cathepsin Inhibitors as Anti-Ebola Agents. Acs Infectious Diseases. 2: 173-179. PMID 27347558 DOI: 10.1021/Acsinfecdis.5B00130 |
0.336 |
|
| 2016 |
Maier KE, Jangra RK, Shieh KR, Cureton DK, Xiao H, Snapp EL, Whelan SP, Chandran K, Levy M. A New Transferrin Receptor Aptamer Inhibits New World Hemorrhagic Fever Mammarenavirus Entry. Molecular Therapy. Nucleic Acids. 5: e321. PMID 27219515 DOI: 10.1038/Mtna.2016.32 |
0.322 |
|
| 2016 |
Spence JS, Krause TB, Mittler E, Jangra RK, Chandran K. Direct Visualization of Ebola Virus Fusion Triggering in the Endocytic Pathway. Mbio. 7. PMID 26861015 DOI: 10.1128/Mbio.01857-15 |
0.403 |
|
| 2016 |
Frei JC, Nyakatura EK, Zak SE, Bakken RR, Chandran K, Dye JM, Lai JR. Bispecific Antibody Affords Complete Post-Exposure Protection of Mice from Both Ebola (Zaire) and Sudan Viruses. Scientific Reports. 6: 19193. PMID 26758505 DOI: 10.1038/Srep19193 |
0.307 |
|
| 2015 |
Bornholdt ZA, Ndungo E, Fusco ML, Bale S, Flyak AI, Crowe JE, Chandran K, Saphire EO. Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies. Mbio. 7. PMID 26908579 DOI: 10.1128/Mbio.02154-15 |
0.349 |
|
| 2015 |
Ng M, Ndungo E, Kaczmarek ME, Herbert AS, Binger T, Kuehne AI, Jangra RK, Hawkins JA, Gifford RJ, Biswas R, Demogines A, James RM, Yu M, Brummelkamp TR, Drosten C, ... ... Chandran K, et al. Filovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats. Elife. 4. PMID 26698106 DOI: 10.7554/Elife.11785 |
0.342 |
|
| 2015 |
Basu A, Mills DM, Mitchell D, Ndungo E, Williams JD, Herbert AS, Dye JM, Moir DT, Chandran K, Patterson JL, Rong L, Bowlin TL. Novel Small Molecule Entry Inhibitors of Ebola Virus. The Journal of Infectious Diseases. 212: S425-34. PMID 26206510 DOI: 10.1093/Infdis/Jiv223 |
0.36 |
|
| 2015 |
Kleinfelter LM, Jangra RK, Jae LT, Herbert AS, Mittler E, Stiles KM, Wirchnianski AS, Kielian M, Brummelkamp TR, Dye JM, Chandran K. Haploid Genetic Screen Reveals a Profound and Direct Dependence on Cholesterol for Hantavirus Membrane Fusion. Mbio. 6. PMID 26126854 DOI: 10.1128/Mbio.00801-15 |
0.387 |
|
| 2015 |
Herbert AS, Davidson C, Kuehne AI, Bakken R, Braigen SZ, Gunn KE, Whelan SP, Brummelkamp TR, Twenhafel NA, Chandran K, Walkley SU, Dye JM. Niemann-pick C1 is essential for ebolavirus replication and pathogenesis in vivo. Mbio. 6: e00565-15. PMID 26015498 DOI: 10.1128/Mbio.00565-15 |
0.319 |
|
| 2014 |
Ng M, Ndungo E, Jangra RK, Cai Y, Postnikova E, Radoshitzky SR, Dye JM, Ramírez de Arellano E, Negredo A, Palacios G, Kuhn JH, Chandran K. Cell entry by a novel European filovirus requires host endosomal cysteine proteases and Niemann-Pick C1. Virology. 468: 637-46. PMID 25310500 DOI: 10.1016/J.Virol.2014.08.019 |
0.345 |
|
| 2014 |
Lennemann NJ, Rhein BA, Ndungo E, Chandran K, Qiu X, Maury W. Comprehensive functional analysis of N-linked glycans on Ebola virus GP1. Mbio. 5: e00862-13. PMID 24473128 DOI: 10.1128/Mbio.00862-13 |
0.328 |
|
| 2014 |
Koellhoffer JF, Dai Z, Malashkevich VN, Stenglein MD, Liu Y, Toro R, S Harrison J, Chandran K, DeRisi JL, Almo SC, Lai JR. Structural characterization of the glycoprotein GP2 core domain from the CAS virus, a novel arenavirus-like species. Journal of Molecular Biology. 426: 1452-68. PMID 24333483 DOI: 10.1016/J.Jmb.2013.12.009 |
0.383 |
|
| 2014 |
Kuhn JH, Bào Y, Bavari S, Becker S, Bradfute S, Brauburger K, Rodney Brister J, Bukreyev AA, Caì Y, Chandran K, Davey RA, Dolnik O, Dye JM, Enterlein S, Gonzalez JP, et al. Virus nomenclature below the species level: a standardized nomenclature for filovirus strains and variants rescued from cDNA. Archives of Virology. 159: 1229-37. PMID 24190508 DOI: 10.1007/S00705-013-1877-2 |
0.344 |
|
| 2013 |
Higgins CD, Koellhoffer JF, Chandran K, Lai JR. C-peptide inhibitors of Ebola virus glycoprotein-mediated cell entry: effects of conjugation to cholesterol and side chain-side chain crosslinking. Bioorganic & Medicinal Chemistry Letters. 23: 5356-60. PMID 23962564 DOI: 10.1016/J.Bmcl.2013.07.056 |
0.318 |
|
| 2013 |
Regula LK, Harris R, Wang F, Higgins CD, Koellhoffer JF, Zhao Y, Chandran K, Gao J, Girvin ME, Lai JR. Conformational properties of peptides corresponding to the ebolavirus GP2 membrane-proximal external region in the presence of micelle-forming surfactants and lipids. Biochemistry. 52: 3393-404. PMID 23650881 DOI: 10.1021/Bi400040V |
0.384 |
|
| 2013 |
Kuhn JH, Bao Y, Bavari S, Becker S, Bradfute S, Brister JR, Bukreyev AA, Caì Y, Chandran K, Davey RA, Dolnik O, Dye JM, Enterlein S, Gonzalez JP, Formenty P, et al. Virus nomenclature below the species level: a standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae. Archives of Virology. 158: 1425-32. PMID 23358612 DOI: 10.1007/S00705-012-1594-2 |
0.31 |
|
| 2013 |
Martinez O, Ndungo E, Tantral L, Miller EH, Leung LW, Chandran K, Basler CF. A mutation in the Ebola virus envelope glycoprotein restricts viral entry in a host species- and cell-type-specific manner. Journal of Virology. 87: 3324-34. PMID 23302883 DOI: 10.1128/Jvi.01598-12 |
0.361 |
|
| 2013 |
Kuhn JH, Bao Y, Bavari S, Becker S, Bradfute S, Brister JR, Bukreyev AA, Chandran K, Davey RA, Dolnik O, Dye JM, Enterlein S, Hensley LE, Honko AN, Jahrling PB, et al. Virus nomenclature below the species level: a standardized nomenclature for natural variants of viruses assigned to the family Filoviridae. Archives of Virology. 158: 301-11. PMID 23001720 DOI: 10.1007/S00705-012-1454-0 |
0.313 |
|
| 2012 |
Bhattacharyya S, Mulherkar N, Chandran K. Endocytic pathways involved in filovirus entry: advances, implications and future directions. Viruses. 4: 3647-64. PMID 23342373 DOI: 10.3390/V4123647 |
0.347 |
|
| 2012 |
Krishnan A, Miller EH, Herbert AS, Ng M, Ndungo E, Whelan SP, Dye JM, Chandran K. Niemann-Pick C1 (NPC1)/NPC1-like1 chimeras define sequences critical for NPC1's function as a flovirus entry receptor. Viruses. 4: 2471-84. PMID 23202491 DOI: 10.3390/V4112471 |
0.306 |
|
| 2012 |
Koellhoffer JF, Chen G, Sandesara RG, Bale S, Saphire EO, Chandran K, Sidhu SS, Lai JR. Two synthetic antibodies that recognize and neutralize distinct proteolytic forms of the ebola virus envelope glycoprotein. Chembiochem : a European Journal of Chemical Biology. 13: 2549-57. PMID 23111988 DOI: 10.1002/Cbic.201200493 |
0.367 |
|
| 2012 |
Koellhoffer JF, Malashkevich VN, Harrison JS, Toro R, Bhosle RC, Chandran K, Almo SC, Lai JR. Crystal structure of the Marburg virus GP2 core domain in its postfusion conformation. Biochemistry. 51: 7665-75. PMID 22935026 DOI: 10.1021/Bi300976M |
0.369 |
|
| 2012 |
Bale S, Dias JM, Fusco ML, Hashiguchi T, Wong AC, Liu T, Keuhne AI, Li S, Woods VL, Chandran K, Dye JM, Saphire EO. Structural basis for differential neutralization of ebolaviruses. Viruses. 4: 447-70. PMID 22590681 DOI: 10.3390/V4040447 |
0.339 |
|
| 2012 |
Miller EH, Chandran K. Filovirus entry into cells - new insights. Current Opinion in Virology. 2: 206-14. PMID 22445965 DOI: 10.1016/J.Coviro.2012.02.015 |
0.387 |
|
| 2012 |
Miller EH, Obernosterer G, Raaben M, Herbert AS, Deffieu MS, Krishnan A, Ndungo E, Sandesara RG, Carette JE, Kuehne AI, Ruthel G, Pfeffer SR, Dye JM, Whelan SP, Brummelkamp TR, ... Chandran K, et al. Ebola virus entry requires the host-programmed recognition of an intracellular receptor. The Embo Journal. 31: 1947-60. PMID 22395071 DOI: 10.1038/Emboj.2012.53 |
0.372 |
|
| 2012 |
Harrison JS, Koellhoffer JF, Chandran K, Lai JR. Marburg virus glycoprotein GP2: pH-dependent stability of the ectodomain α-helical bundle. Biochemistry. 51: 2515-25. PMID 22369502 DOI: 10.1021/Bi3000353 |
0.347 |
|
| 2012 |
Misasi J, Chandran K, Yang JY, Considine B, Filone CM, Côté M, Sullivan N, Fabozzi G, Hensley L, Cunningham J. Filoviruses require endosomal cysteine proteases for entry but exhibit distinct protease preferences. Journal of Virology. 86: 3284-92. PMID 22238307 DOI: 10.1128/Jvi.06346-11 |
0.312 |
|
| 2011 |
Dias JM, Kuehne AI, Abelson DM, Bale S, Wong AC, Halfmann P, Muhammad MA, Fusco ML, Zak SE, Kang E, Kawaoka Y, Chandran K, Dye JM, Saphire EO. A shared structural solution for neutralizing ebolaviruses. Nature Structural & Molecular Biology. 18: 1424-7. PMID 22101933 DOI: 10.1038/Nsmb.2150 |
0.31 |
|
| 2011 |
Martinez O, Tantral L, Mulherkar N, Chandran K, Basler CF. Impact of Ebola mucin-like domain on antiglycoprotein antibody responses induced by Ebola virus-like particles. The Journal of Infectious Diseases. 204: S825-32. PMID 21987758 DOI: 10.1093/Infdis/Jir295 |
0.36 |
|
| 2011 |
Mulherkar N, Raaben M, de la Torre JC, Whelan SP, Chandran K. The Ebola virus glycoprotein mediates entry via a non-classical dynamin-dependent macropinocytic pathway. Virology. 419: 72-83. PMID 21907381 DOI: 10.1016/J.Virol.2011.08.009 |
0.397 |
|
| 2011 |
Carette JE, Raaben M, Wong AC, Herbert AS, Obernosterer G, Mulherkar N, Kuehne AI, Kranzusch PJ, Griffin AM, Ruthel G, Dal Cin P, Dye JM, Whelan SP, Chandran K, Brummelkamp TR. Ebola virus entry requires the cholesterol transporter Niemann-Pick C1. Nature. 477: 340-3. PMID 21866103 DOI: 10.1038/Nature10348 |
0.425 |
|
| 2011 |
Côté M, Misasi J, Ren T, Bruchez A, Lee K, Filone CM, Hensley L, Li Q, Ory D, Chandran K, Cunningham J. Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection. Nature. 477: 344-8. PMID 21866101 DOI: 10.1038/Nature10380 |
0.368 |
|
| 2011 |
Harrison JS, Higgins CD, Chandran K, Lai JR. Designed protein mimics of the Ebola virus glycoprotein GP2 α-helical bundle: stability and pH effects. Protein Science : a Publication of the Protein Society. 20: 1587-96. PMID 21739501 DOI: 10.1002/Pro.688 |
0.39 |
|
| 2011 |
Miller EH, Harrison JS, Radoshitzky SR, Higgins CD, Chi X, Dong L, Kuhn JH, Bavari S, Lai JR, Chandran K. Inhibition of Ebola virus entry by a C-peptide targeted to endosomes. The Journal of Biological Chemistry. 286: 15854-61. PMID 21454542 DOI: 10.1074/Jbc.M110.207084 |
0.37 |
|
| 2010 |
Wong AC, Sandesara RG, Mulherkar N, Whelan SP, Chandran K. A forward genetic strategy reveals destabilizing mutations in the Ebolavirus glycoprotein that alter its protease dependence during cell entry. Journal of Virology. 84: 163-75. PMID 19846533 DOI: 10.1128/Jvi.01832-09 |
0.357 |
|
| 2008 |
Ivanovic T, Agosto MA, Zhang L, Chandran K, Harrison SC, Nibert ML. Peptides released from reovirus outer capsid form membrane pores that recruit virus particles. The Embo Journal. 27: 1289-98. PMID 18369316 DOI: 10.1038/Emboj.2008.60 |
0.771 |
|
| 2007 |
Ivanovic T, Agosto MA, Chandran K, Nibert ML. A role for molecular chaperone Hsc70 in reovirus outer capsid disassembly. The Journal of Biological Chemistry. 282: 12210-9. PMID 17284448 DOI: 10.1074/Jbc.M610258200 |
0.773 |
|
| 2006 |
Zhang L, Chandran K, Nibert ML, Harrison SC. Reovirus mu1 structural rearrangements that mediate membrane penetration. Journal of Virology. 80: 12367-76. PMID 17005655 DOI: 10.1128/Jvi.01343-06 |
0.613 |
|
| 2006 |
Coffey CM, Sheh A, Kim IS, Chandran K, Nibert ML, Parker JS. Reovirus outer capsid protein micro1 induces apoptosis and associates with lipid droplets, endoplasmic reticulum, and mitochondria. Journal of Virology. 80: 8422-38. PMID 16912293 DOI: 10.1128/Jvi.02601-05 |
0.574 |
|
| 2005 |
Chandran K, Sullivan NJ, Felbor U, Whelan SP, Cunningham JM. Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection. Science (New York, N.Y.). 308: 1643-5. PMID 15831716 DOI: 10.1126/Science.1110656 |
0.361 |
|
| 2005 |
Nibert ML, Odegard AL, Agosto MA, Chandran K, Schiff LA. Putative autocleavage of reovirus mu1 protein in concert with outer-capsid disassembly and activation for membrane permeabilization. Journal of Molecular Biology. 345: 461-74. PMID 15581891 DOI: 10.1016/J.Jmb.2004.10.026 |
0.791 |
|
| 2004 |
Ehrlich M, Boll W, Van Oijen A, Hariharan R, Chandran K, Nibert ML, Kirchhausen T. Endocytosis by random initiation and stabilization of clathrin-coated pits. Cell. 118: 591-605. PMID 15339664 DOI: 10.1016/J.Cell.2004.08.017 |
0.571 |
|
| 2004 |
Odegard AL, Chandran K, Zhang X, Parker JS, Baker TS, Nibert ML. Putative autocleavage of outer capsid protein micro1, allowing release of myristoylated peptide micro1N during particle uncoating, is critical for cell entry by reovirus. Journal of Virology. 78: 8732-45. PMID 15280481 DOI: 10.1128/Jvi.78.16.8732-8745.2004 |
0.667 |
|
| 2004 |
Hutchings AB, Helander A, Silvey KJ, Chandran K, Lucas WT, Nibert ML, Neutra MR. Secretory immunoglobulin A antibodies against the sigma1 outer capsid protein of reovirus type 1 Lang prevent infection of mouse Peyer's patches. Journal of Virology. 78: 947-57. PMID 14694126 DOI: 10.1128/Jvi.78.2.947-957.2004 |
0.575 |
|
| 2003 |
Chandran K, Parker JS, Ehrlich M, Kirchhausen T, Nibert ML. The delta region of outer-capsid protein micro 1 undergoes conformational change and release from reovirus particles during cell entry. Journal of Virology. 77: 13361-75. PMID 14645591 DOI: 10.1128/Jvi.77.24.13361-13375.2003 |
0.632 |
|
| 2003 |
Chandran K, Nibert ML. Animal cell invasion by a large nonenveloped virus: reovirus delivers the goods. Trends in Microbiology. 11: 374-82. PMID 12915095 DOI: 10.1016/S0966-842X(03)00178-1 |
0.619 |
|
| 2003 |
Helander A, Silvey KJ, Mantis NJ, Hutchings AB, Chandran K, Lucas WT, Nibert ML, Neutra MR. The viral sigma1 protein and glycoconjugates containing alpha2-3-linked sialic acid are involved in type 1 reovirus adherence to M cell apical surfaces. Journal of Virology. 77: 7964-77. PMID 12829836 DOI: 10.1128/Jvi.77.14.7964-7977.2003 |
0.592 |
|
| 2003 |
Odegard AL, Chandran K, Liemann S, Harrison SC, Nibert ML. Disulfide bonding among micro 1 trimers in mammalian reovirus outer capsid: a late and reversible step in virion morphogenesis. Journal of Virology. 77: 5389-400. PMID 12692241 DOI: 10.1128/Jvi.77.9.5389-5400.2003 |
0.597 |
|
| 2002 |
Chandran K, Farsetta DL, Nibert ML. Strategy for nonenveloped virus entry: a hydrophobic conformer of the reovirus membrane penetration protein micro 1 mediates membrane disruption. Journal of Virology. 76: 9920-33. PMID 12208969 DOI: 10.1128/Jvi.76.19.9920-9933.2002 |
0.793 |
|
| 2002 |
Liemann S, Chandran K, Baker TS, Nibert ML, Harrison SC. Structure of the reovirus membrane-penetration protein, Mu1, in a complex with is protector protein, Sigma3. Cell. 108: 283-95. PMID 11832217 DOI: 10.1016/S0092-8674(02)00612-8 |
0.61 |
|
| 2002 |
Middleton JK, Severson TF, Chandran K, Gillian AL, Yin J, Nibert ML. Thermostability of reovirus disassembly intermediates (ISVPs) correlates with genetic, biochemical, and thermodynamic properties of major surface protein mu1. Journal of Virology. 76: 1051-61. PMID 11773381 DOI: 10.1128/Jvi.76.3.1051-1061.2002 |
0.602 |
|
| 2001 |
Chandran K, Zhang X, Olson NH, Walker SB, Chappell JD, Dermody TS, Baker TS, Nibert ML. Complete in vitro assembly of the reovirus outer capsid produces highly infectious particles suitable for genetic studies of the receptor-binding protein. Journal of Virology. 75: 5335-42. PMID 11333914 DOI: 10.1128/Jvi.75.11.5335-5342.2001 |
0.642 |
|
| 2000 |
Farsetta DL, Chandran K, Nibert ML. Transcriptional activities of reovirus RNA polymerase in recoated cores Journal of Biological Chemistry. 275: 39693-39701. PMID 11007773 DOI: 10.1074/Jbc.M004562200 |
0.76 |
|
| 1999 |
Chandran K, Walker SB, Chen Y, Contreras CM, Schiff LA, Baker TS, Nibert ML. In vitro recoating of reovirus cores with baculovirus-expressed outer-capsid proteins mu1 and sigma3. Journal of Virology. 73: 3941-50. PMID 10196289 DOI: 10.1128/Jvi.73.5.3941-3950.1999 |
0.631 |
|
| 1998 |
Chandran K, Nibert ML. Protease cleavage of reovirus capsid protein μ1/μ1C is blocked by alkyl sulfate detergents, yielding a new type of infectious subvirion particle Journal of Virology. 72: 467-475. PMID 9420247 DOI: 10.1128/Jvi.72.1.467-475.1998 |
0.674 |
|
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