Koichi Ikuta - Publications

Affiliations: 
1992-1996 University of Tokyo, Bunkyō-ku, Tōkyō-to, Japan 
 1996- Kyoto University, Kyōto-shi, Kyōto-fu, Japan 
Area:
Immunology

122 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Abe S, Asahi T, Hara T, Cui G, Shimba A, Tani-Ichi S, Yamada K, Miyazaki K, Miyachi H, Kitano S, Nakamura N, Kikuta J, Vandenbon A, Miyazaki M, Yamada R, ... ... Ikuta K, et al. Hematopoietic cell-derived IL-15 supports NK cell development in scattered and clustered localization within the bone marrow. Cell Reports. 42: 113127. PMID 37729919 DOI: 10.1016/j.celrep.2023.113127  0.361
2023 Asahi T, Abe S, Cui G, Shimba A, Nabekura T, Miyachi H, Kitano S, Ohira K, Dijkstra JM, Miyazaki M, Shibuya A, Ohno H, Ikuta K. Liver type 1 innate lymphoid cells lacking IL-7 receptor are a native killer cell subset fostered by parenchymal niches. Elife. 12. PMID 37352115 DOI: 10.7554/eLife.84209  0.306
2022 Cui G, Shimba A, Jin J, Ogawa T, Muramoto Y, Miyachi H, Abe S, Asahi T, Tani-Ichi S, Dijkstra JM, Iwamoto Y, Kryukov K, Zhu Y, Takami D, Hara T, ... ... Ikuta K, et al. A circulating subset of iNKT cells mediates antitumor and antiviral immunity. Science Immunology. 7: eabj8760. PMID 36269840 DOI: 10.1126/sciimmunol.abj8760  0.356
2022 Rodríguez-Caparrós A, Tani-Ichi S, Casal Á, López-Ros J, Suñé C, Ikuta K, Hernández-Munain C. Interleukin-7 receptor signaling is crucial for enhancer-dependent TCRδ germline transcription mediated through STAT5 recruitment. Frontiers in Immunology. 13: 943510. PMID 36059467 DOI: 10.3389/fimmu.2022.943510  0.316
2022 Ejima A, Abe S, Shimba A, Sato S, Uehata T, Tani-Ichi S, Munakata S, Cui G, Takeuchi O, Hirai T, Kato S, Ikuta K. Androgens Alleviate Allergic Airway Inflammation by Suppressing Cytokine Production in Th2 Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 35977797 DOI: 10.4049/jimmunol.2200294  0.351
2022 Das Gupta D, Paul C, Samel N, Bieringer M, Staudenraus D, Marini F, Raifer H, Menke L, Hansal L, Camara B, Roth E, Daum P, Wanzel M, Mernberger M, Nist A, ... ... Ikuta K, et al. IRF4 deficiency vulnerates B-cell progeny for leukemogenesis via somatically acquired Jak3 mutations conferring IL-7 hypersensitivity. Cell Death and Differentiation. PMID 35459909 DOI: 10.1038/s41418-022-01005-z  0.372
2021 Ikuta K, Hara T, Abe S, Asahi T, Takami D, Cui G. The Roles of IL-7 and IL-15 in Niches for Lymphocyte Progenitors and Immune Cells in Lymphoid Organs. Current Topics in Microbiology and Immunology. 434: 83-101. PMID 34850283 DOI: 10.1007/978-3-030-86016-5_4  0.357
2021 Ullrich L, Lueder Y, Juergens AL, Wilharm A, Barros-Martins J, Bubke A, Demera A, Ikuta K, Patzer GE, Janssen A, Sandrock I, Prinz I, Rampoldi F. IL-4-Producing Vγ1/Vδ6 γδ T Cells Sustain Germinal Center Reactions in Peyer's Patches of Mice. Frontiers in Immunology. 12: 729607. PMID 34804014 DOI: 10.3389/fimmu.2021.729607  0.408
2021 Kuwano T, Izumi H, Aslam MR, Igarashi Y, Bilal M, Nishimura A, Watanabe Y, Nawaz A, Kado T, Ikuta K, Yamamoto S, Sasahara M, Fujisaka S, Yagi K, Mori H, et al. Generation and characterization of a Meflin-CreERT2 transgenic line for lineage tracing in white adipose tissue. Plos One. 16: e0248267. PMID 33760832 DOI: 10.1371/journal.pone.0248267  0.328
2020 Miyazaki K, Watanabe H, Yoshikawa G, Chen K, Hidaka R, Aitani Y, Osawa K, Takeda R, Ochi Y, Tani-Ichi S, Uehata T, Takeuchi O, Ikuta K, Ogawa S, Kondoh G, et al. The transcription factor E2A activates multiple enhancers that drive expression in developing T and B cells. Science Immunology. 5. PMID 32887843 DOI: 10.1126/Sciimmunol.Abb1455  0.441
2020 Shimba A, Ikuta K. Immune-enhancing effects of glucocorticoids in response to day-night cycles and stress. International Immunology. PMID 32710629 DOI: 10.1093/Intimm/Dxaa048  0.435
2020 Tani-Ichi S, Wagatsuma K, Hara T, Cui G, Abe S, Miyachi H, Kitano S, Ikuta K. Innate-like CD27CD45RB γδ T Cells Require TCR Signaling for Homeostasis in Peripheral Lymphoid Organs. Journal of Immunology (Baltimore, Md. : 1950). PMID 32238459 DOI: 10.4049/Jimmunol.1801243  0.471
2020 Inokawa H, Umemura Y, Shimba A, Kawakami E, Koike N, Tsuchiya Y, Ohashi M, Minami Y, Cui G, Asahi T, Ono R, Sasawaki Y, Konishi E, Yoo SH, Chen Z, ... ... Ikuta K, et al. Chronic circadian misalignment accelerates immune senescence and abbreviates lifespan in mice. Scientific Reports. 10: 2569. PMID 32054990 DOI: 10.1038/S41598-020-59541-Y  0.36
2020 Cui G, Shimba A, Ma G, Takahara K, Tani-Ichi S, Zhu Y, Asahi T, Abe A, Miyachi H, Kitano S, Hara T, Yasunaga JI, Suwanai H, Yamada H, Matsuoka M, ... ... Ikuta K, et al. IL-7R-Dependent Phosphatidylinositol 3-Kinase Competes with the STAT5 Signal to Modulate T Cell Development and Homeostasis. Journal of Immunology (Baltimore, Md. : 1950). PMID 31924648 DOI: 10.4049/Jimmunol.1900456  0.442
2020 Shimba A, Ikuta K. Glucocorticoids Regulate Circadian Rhythm of Innate and Adaptive Immunity Frontiers in Immunology. 11. DOI: 10.3389/Fimmu.2020.02143  0.36
2019 Zhu Y, Cui G, Miyauchi E, Nakanishi Y, Mukohira H, Shimba A, Abe S, Tani-Ichi S, Hara T, Nakase H, Chiba T, Sehara-Fujisawa A, Seno H, Ohno H, Ikuta K. Intestinal epithelial cell-derived IL-15 determines local maintenance and maturation of intraepithelial lymphocytes in the intestine. International Immunology. PMID 31875880 DOI: 10.1093/Intimm/Dxz082  0.42
2019 Mukohira H, Hara T, Abe S, Tani-Ichi S, Sehara-Fujisawa A, Nagasawa T, Tobe K, Ikuta K. Mesenchymal Stromal Cells in Bone Marrow Express Adiponectin and Are Efficiently Targeted by an Adiponectin Promoter-Driven Cre Transgene. International Immunology. PMID 31094421 DOI: 10.1093/Intimm/Dxz042  0.466
2019 Rodríguez-Caparrós A, García V, Casal Á, López-Ros J, García-Mariscal A, Tani-Ichi S, Ikuta K, Hernández-Munain C. Notch Signaling Controls Transcription via the Recruitment of RUNX1 and MYB to Enhancers during T Cell Development. Journal of Immunology (Baltimore, Md. : 1950). PMID 30877169 DOI: 10.4049/Jimmunol.1801650  0.333
2018 Baumann NS, Torti N, Welten SPM, Barnstorf I, Borsa M, Pallmer K, Oduro JD, Cicin-Sain L, Ikuta K, Ludewig B, Oxenius A. Tissue maintenance of CMV-specific inflationary memory T cells by IL-15. Plos Pathogens. 14: e1006993. PMID 29652930 DOI: 10.1371/Journal.Ppat.1006993  0.459
2018 Shimba A, Cui G, Tani-Ichi S, Ogawa M, Abe S, Okazaki F, Kitano S, Miyachi H, Yamada H, Hara T, Yoshikai Y, Nagasawa T, Schütz G, Ikuta K. Glucocorticoids Drive Diurnal Oscillations in T Cell Distribution and Responses by Inducing Interleukin-7 Receptor and CXCR4. Immunity. 48: 286-298.e6. PMID 29396162 DOI: 10.1016/J.Immuni.2018.01.004  0.481
2017 Nakamizo S, Honda T, Adachi A, Nagatake T, Kunisawa J, Kitoh A, Otsuka A, Dainichi T, Nomura T, Ginhoux F, Ikuta K, Egawa G, Kabashima K. High fat diet exacerbates murine psoriatic dermatitis by increasing the number of IL-17-producing γδ T cells. Scientific Reports. 7: 14076. PMID 29074858 DOI: 10.1038/S41598-017-14292-1  0.4
2016 Cordeiro Gomes A, Hara T, Lim VY, Herndler-Brandstetter D, Nevius E, Sugiyama T, Tani-Ichi S, Schlenner S, Richie E, Rodewald HR, Flavell RA, Nagasawa T, Ikuta K, Pereira JP. Hematopoietic Stem Cell Niches Produce Lineage-Instructive Signals to Control Multipotent Progenitor Differentiation. Immunity. PMID 27913094 DOI: 10.1016/J.Immuni.2016.11.004  0.491
2016 Gil-Cruz C, Perez-Shibayama C, Onder L, Chai Q, Cupovic J, Cheng HW, Novkovic M, Lang PA, Geuking MB, McCoy KD, Abe S, Cui G, Ikuta K, Scandella E, Ludewig B. Fibroblastic reticular cells regulate intestinal inflammation via IL-15-mediated control of group 1 ILCs. Nature Immunology. PMID 27798617 DOI: 10.1038/Ni.3566  0.42
2016 Terashima A, Okamoto K, Nakashima T, Akira S, Ikuta K, Takayanagi H. Sepsis-Induced Osteoblast Ablation Causes Immunodeficiency. Immunity. 44: 1434-43. PMID 27317262 DOI: 10.1016/J.Immuni.2016.05.012  0.382
2016 Shinoda K, Hirahara K, Iinuma T, Ichikawa T, Suzuki AS, Sugaya K, Tumes DJ, Yamamoto H, Hara T, Tani-Ichi S, Ikuta K, Okamoto Y, Nakayama T. Thy1+IL-7+ lymphatic endothelial cells in iBALT provide a survival niche for memory T-helper cells in allergic airway inflammation. Proceedings of the National Academy of Sciences of the United States of America. 113: E2842-51. PMID 27140620 DOI: 10.1073/Pnas.1512600113  0.416
2015 Huang Y, Getahun A, Heiser RA, Detanico TO, Aviszus K, Kirchenbaum GA, Casper TL, Huang C, Aydintug MK, Carding SR, Ikuta K, Huang H, Wysocki LJ, Cambier JC, O'Brien RL, et al. γδ T Cells Shape Preimmune Peripheral B Cell Populations. Journal of Immunology (Baltimore, Md. : 1950). PMID 26582947 DOI: 10.4049/Jimmunol.1501064  0.516
2015 Adachi T, Kobayashi T, Sugihara E, Yamada T, Ikuta K, Pittaluga S, Saya H, Amagai M, Nagao K. Hair follicle-derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma. Nature Medicine. 21: 1272-9. PMID 26479922 DOI: 10.1038/Nm.3962  0.417
2015 Nishijima H, Kitano S, Miyachi H, Morimoto J, Kawano H, Hirota F, Morita R, Mouri Y, Masuda K, Imoto I, Ikuta K, Matsumoto M. Ectopic Aire Expression in the Thymic Cortex Reveals Inherent Properties of Aire as a Tolerogenic Factor within the Medulla. Journal of Immunology (Baltimore, Md. : 1950). 195: 4641-9. PMID 26453754 DOI: 10.4049/Jimmunol.1501026  0.321
2015 Abe A, Tani-Ichi S, Shitara S, Cui G, Yamada H, Miyachi H, Kitano S, Hara T, Abe R, Yoshikai Y, Ikuta K. An Enhancer of the IL-7 Receptor α-Chain Locus Controls IL-7 Receptor Expression and Maintenance of Peripheral T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 26336149 DOI: 10.4049/Jimmunol.1302447  0.485
2015 Wagatsuma K, Tani-Ichi S, Liang B, Shitara S, Ishihara K, Abe M, Miyachi H, Kitano S, Hara T, Nanno M, Ishikawa H, Sakimura K, Nakao M, Kimura H, Ikuta K. STAT5 Orchestrates Local Epigenetic Changes for Chromatin Accessibility and Rearrangements by Direct Binding to the TCRγ Locus. Journal of Immunology (Baltimore, Md. : 1950). PMID 26195811 DOI: 10.4049/Jimmunol.1302456  0.39
2015 Sercan Alp Ö, Durlanik S, Schulz D, McGrath M, Grün JR, Bardua M, Ikuta K, Sgouroudis E, Riedel R, Zehentmeier S, Hauser AE, Tsuneto M, Melchers F, Tokoyoda K, Chang HD, et al. Memory CD8(+) T cells colocalize with IL-7(+) stromal cells in bone marrow and rest in terms of proliferation and transcription. European Journal of Immunology. 45: 975-87. PMID 25639669 DOI: 10.1002/Eji.201445295  0.44
2015 Huang Y, Heiser RA, Detanico TO, Getahun A, Kirchenbaum GA, Casper TL, Aydintug MK, Carding SR, Ikuta K, Huang H, Cambier JC, Wysocki LJ, O'Brien RL, Born WK. γδ T cells affect IL-4 production and B-cell tolerance. Proceedings of the National Academy of Sciences of the United States of America. 112: E39-48. PMID 25535377 DOI: 10.1073/Pnas.1415107111  0.521
2015 Nakamura M, Shibata K, Hatano S, Sato T, Ohkawa Y, Yamada H, Ikuta K, Yoshikai Y. A genome-wide analysis identifies a notch-RBP-Jκ-IL-7Rα axis that controls IL-17-producing γδ T cell homeostasis in mice. Journal of Immunology (Baltimore, Md. : 1950). 194: 243-51. PMID 25429074 DOI: 10.4049/Jimmunol.1401619  0.453
2014 Tsuneto M, Kajikhina E, Seiler K, Reimer A, Tornack J, Bouquet C, Simmons S, Knoll M, Wolf I, Tokoyoda K, Hauser A, Hara T, Tani-ichi S, Ikuta K, Grün JR, et al. Reprint of: Environments of B cell development. Immunology Letters. 160: 109-12. PMID 24852107 DOI: 10.1016/J.Imlet.2014.05.005  0.432
2014 Cui G, Hara T, Simmons S, Wagatsuma K, Abe A, Miyachi H, Kitano S, Ishii M, Tani-ichi S, Ikuta K. Characterization of the IL-15 niche in primary and secondary lymphoid organs in vivo. Proceedings of the National Academy of Sciences of the United States of America. 111: 1915-20. PMID 24449915 DOI: 10.1073/Pnas.1318281111  0.465
2014 Tsuneto M, Kajikhina E, Seiler K, Reimer A, Tornack J, Bouquet C, Simmons S, Knoll M, Wolf I, Tokoyoda K, Hauser A, Hara T, Tani-ichi S, Ikuta K, Grün JR, et al. Environments of B cell development. Immunology Letters. 157: 60-3. PMID 24284375 DOI: 10.1016/J.Imlet.2013.11.011  0.432
2013 Hanazawa A, Hayashizaki K, Shinoda K, Yagita H, Okumura K, Löhning M, Hara T, Tani-ichi S, Ikuta K, Eckes B, Radbruch A, Tokoyoda K, Nakayama T. CD49b-dependent establishment of T helper cell memory. Immunology and Cell Biology. 91: 524-31. PMID 23897120 DOI: 10.1038/Icb.2013.36  0.391
2013 Lee JK, Won C, Yi EH, Seok SH, Kim MH, Kim SJ, Chung MH, Lee HG, Ikuta K, Ye SK. Signal transducer and activator of transcription 3 (Stat3) contributes to T-cell homeostasis by regulating pro-survival Bcl-2 family genes. Immunology. 140: 288-300. PMID 23746113 DOI: 10.1111/Imm.12133  0.444
2013 Shitara S, Hara T, Liang B, Wagatsuma K, Zuklys S, Holländer GA, Nakase H, Chiba T, Tani-ichi S, Ikuta K. IL-7 produced by thymic epithelial cells plays a major role in the development of thymocytes and TCRγδ+ intraepithelial lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 190: 6173-9. PMID 23686483 DOI: 10.4049/Jimmunol.1202573  0.436
2013 Tsuneto M, Tokoyoda K, Kajikhina E, Hauser AE, Hara T, Tani-Ichi S, Ikuta K, Melchers F. B-cell progenitors and precursors change their microenvironment in fetal liver during early development. Stem Cells (Dayton, Ohio). 31: 2800-12. PMID 23666739 DOI: 10.1002/Stem.1421  0.483
2013 Sekai M, Tani-ichi S, Yoneyama M, Fujita T, Kina T, Ikuta K. Lymphocyte-stromal cell interaction induces IL-7 expression by interferon regulatory factors. Molecular Immunology. 54: 378-85. PMID 23376291 DOI: 10.1016/J.Molimm.2013.01.002  0.437
2013 Tani-ichi S, Shimba A, Wagatsuma K, Miyachi H, Kitano S, Imai K, Hara T, Ikuta K. Interleukin-7 receptor controls development and maturation of late stages of thymocyte subpopulations. Proceedings of the National Academy of Sciences of the United States of America. 110: 612-7. PMID 23267098 DOI: 10.1073/Pnas.1219242110  0.508
2012 Liang B, Hara T, Wagatsuma K, Zhang J, Maki K, Miyachi H, Kitano S, Yabe-Nishimura C, Tani-Ichi S, Ikuta K. Role of hepatocyte-derived IL-7 in maintenance of intrahepatic NKT cells and T cells and development of B cells in fetal liver. Journal of Immunology (Baltimore, Md. : 1950). 189: 4444-50. PMID 23018454 DOI: 10.4049/Jimmunol.1201181  0.47
2012 Hara T, Shitara S, Imai K, Miyachi H, Kitano S, Yao H, Tani-ichi S, Ikuta K. Identification of IL-7-producing cells in primary and secondary lymphoid organs using IL-7-GFP knock-in mice. Journal of Immunology (Baltimore, Md. : 1950). 189: 1577-84. PMID 22786774 DOI: 10.4049/Jimmunol.1200586  0.486
2011 Tani-Ichi S, Satake M, Ikuta K. The pre-TCR signal induces transcriptional silencing of the TCRγ locus by reducing the recruitment of STAT5 and Runx to transcriptional enhancers. International Immunology. 23: 553-63. PMID 21750145 DOI: 10.1093/Intimm/Dxr055  0.43
2011 Ma Y, Aymeric L, Locher C, Mattarollo SR, Delahaye NF, Pereira P, Boucontet L, Apetoh L, Ghiringhelli F, Casares N, Lasarte JJ, Matsuzaki G, Ikuta K, Ryffel B, Benlagha K, et al. Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy. The Journal of Experimental Medicine. 208: 491-503. PMID 21383056 DOI: 10.1084/Jem.20100269  0.445
2011 Shinohara T, Nemoto Y, Kanai T, Kameyama K, Okamoto R, Tsuchiya K, Nakamura T, Totsuka T, Ikuta K, Watanabe M. Upregulated IL-7 receptor α expression on colitogenic memory CD4+ T cells may participate in the development and persistence of chronic colitis. Journal of Immunology (Baltimore, Md. : 1950). 186: 2623-32. PMID 21217010 DOI: 10.4049/Jimmunol.1000057  0.445
2011 Ma Y, Aymeric L, Locher C, Mattarollo SR, Delahaye NF, Pereira P, Boucontet L, Apetoh L, Ghiringhelli F, Casares N, Lasarte JJ, Matsuzaki G, Ikuta K, Ryffel B, Benlagha K, et al. Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy The Journal of Experimental Medicine. 208: 869-869. DOI: 10.1084/Jem.201002692084C  0.447
2010 Tani-ichi S, Lee HC, Ye SK, Ikuta K. Accessibility control of TCR Vγ region by STAT5. International Immunology. 22: 693-703. PMID 20547543 DOI: 10.1093/Intimm/Dxq054  0.381
2010 Okamoto Yoshida Y, Umemura M, Yahagi A, O'Brien RL, Ikuta K, Kishihara K, Hara H, Nakae S, Iwakura Y, Matsuzaki G. Essential role of IL-17A in the formation of a mycobacterial infection-induced granuloma in the lung. Journal of Immunology (Baltimore, Md. : 1950). 184: 4414-22. PMID 20212094 DOI: 10.4049/Jimmunol.0903332  0.386
2009 Tani-ichi S, Satake M, Ikuta K. Activation of the mouse TCRgamma enhancers by STAT5. International Immunology. 21: 1079-88. PMID 19651644 DOI: 10.1093/Intimm/Dxp073  0.368
2009 Tokuriki A, Iyoda T, Inaba K, Ikuta K, Fujimoto S, Kumakiri M, Yokota Y. Dual role for Id2 in chemical carcinogen-induced skin tumorigenesis. Carcinogenesis. 30: 1645-50. PMID 19587095 DOI: 10.1093/Carcin/Bgp172  0.352
2008 Lee HC, Headley MB, Iseki M, Ikuta K, Ziegler SF. Cutting edge: Inhibition of NF-kappaB-mediated TSLP expression by retinoid X receptor. Journal of Immunology (Baltimore, Md. : 1950). 181: 5189-93. PMID 18832669 DOI: 10.4049/Jimmunol.181.8.5189  0.33
2008 Hamada S, Umemura M, Shiono T, Tanaka K, Yahagi A, Begum MD, Oshiro K, Okamoto Y, Watanabe H, Kawakami K, Roark C, Born WK, O'Brien R, Ikuta K, Ishikawa H, et al. IL-17A produced by gammadelta T cells plays a critical role in innate immunity against listeria monocytogenes infection in the liver. Journal of Immunology (Baltimore, Md. : 1950). 181: 3456-63. PMID 18714018 DOI: 10.4049/Jimmunol.181.5.3456  0.415
2008 Maki K, Ikuta K. MEK1/2 induces STAT5-mediated germline transcription of the TCRgamma locus in response to IL-7R signaling. Journal of Immunology (Baltimore, Md. : 1950). 181: 494-502. PMID 18566415 DOI: 10.4049/Jimmunol.181.1.494  0.396
2008 Ogawa S, Satake M, Ikuta K. Physical and functional interactions between STAT5 and Runx transcription factors. Journal of Biochemistry. 143: 695-709. PMID 18296717 DOI: 10.1093/Jb/Mvn022  0.31
2008 Masui N, Tani-ichi S, Maki K, Ikuta K. Transcriptional activation of mouse TCR Jgamma4 germline promoter by STAT5. Molecular Immunology. 45: 849-55. PMID 17664008 DOI: 10.1016/J.Molimm.2007.06.157  0.392
2007 Shibata H, Tani-ichi S, Lee HC, Maki K, Ikuta K. Induction of the IL-7 receptor alpha chain in mouse peripheral B cells by glucocorticoids. Immunology Letters. 111: 45-50. PMID 17568689 DOI: 10.1016/J.Imlet.2007.04.012  0.42
2007 Nakasone C, Yamamoto N, Nakamatsu M, Kinjo T, Miyagi K, Uezu K, Nakamura K, Higa F, Ishikawa H, O'brien RL, Ikuta K, Kaku M, Fujita J, Kawakami K. Accumulation of gamma/delta T cells in the lungs and their roles in neutrophil-mediated host defense against pneumococcal infection. Microbes and Infection. 9: 251-8. PMID 17306586 DOI: 10.1016/J.Micinf.2006.11.015  0.397
2006 Simonian PL, Roark CL, Diaz del Valle F, Palmer BE, Douglas IS, Ikuta K, Born WK, O'Brien RL, Fontenot AP. Regulatory role of gammadelta T cells in the recruitment of CD4+ and CD8+ T cells to lung and subsequent pulmonary fibrosis. Journal of Immunology (Baltimore, Md. : 1950). 177: 4436-43. PMID 16982878 DOI: 10.4049/Jimmunol.177.7.4436  0.432
2006 Ikuta K, Kageyama R, Honjo T. The 20th IUBMB International Congress in Kyoto. Iubmb Life. 58: 258. PMID 16754309 DOI: 10.1080/15216540600719663  0.416
2005 Lee HC, Shibata H, Ogawa S, Maki K, Ikuta K. Transcriptional regulation of the mouse IL-7 receptor alpha promoter by glucocorticoid receptor. Journal of Immunology (Baltimore, Md. : 1950). 174: 7800-6. PMID 15944284 DOI: 10.4049/Jimmunol.174.12.7800  0.416
2005 Ye SK, Kim TJ, Won SS, Yoon TJ, Park TK, Yoo YC, Kim YN, Lee HC, Ikuta K, Chung MH, Lee KH. Transcriptional regulation of the mouse interleukin-2 receptor beta chain gene by Ets and Egr-1. Biochemical and Biophysical Research Communications. 329: 1094-101. PMID 15752766 DOI: 10.1016/J.Bbrc.2005.02.073  0.354
2003 Kim-Saijo M, Akamizu T, Ikuta K, Iida Y, Ohmori K, Matsubara K, Matsuda Y, Suzuki M, Matsuda F, Nakao K. Generation of a transgenic animal model of hyperthyroid Graves' disease. European Journal of Immunology. 33: 2531-8. PMID 12938229 DOI: 10.1002/Eji.200324255  0.39
2003 Watanabe N, Ikuta K, Okazaki K, Nakase H, Tabata Y, Matsuura M, Tamaki H, Kawanami C, Honjo T, Chiba T. Elimination of local macrophages in intestine prevents chronic colitis in interleukin-10-deficient mice. Digestive Diseases and Sciences. 48: 408-14. PMID 12643623 DOI: 10.1023/A:1021960401290  0.472
2002 Watanabe N, Ikuta K, Nisitani S, Chiba T, Honjo T. Activation and differentiation of autoreactive B-1 cells by interleukin 10 induce autoimmune hemolytic anemia in Fas-deficient antierythrocyte immunoglobulin transgenic mice. The Journal of Experimental Medicine. 196: 141-6. PMID 12093879 DOI: 10.1084/Jem.20011519  0.584
2002 Lahn M, Kanehiro A, Takeda K, Terry J, Hahn YS, Aydintug MK, Konowal A, Ikuta K, O'Brien RL, Gelfand EW, Born WK. MHC class I-dependent Vgamma4+ pulmonary T cells regulate alpha beta T cell-independent airway responsiveness. Proceedings of the National Academy of Sciences of the United States of America. 99: 8850-5. PMID 12070351 DOI: 10.1073/Pnas.132519299  0.459
2002 Han H, Tanigaki K, Yamamoto N, Kuroda K, Yoshimoto M, Nakahata T, Ikuta K, Honjo T. Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision. International Immunology. 14: 637-45. PMID 12039915 DOI: 10.1093/Intimm/Dxf030  0.615
2002 Lee HC, Tomiyama K, Ye SK, Kawai K, Ikuta K. Seeding of dendritic epidermal T cells in the neonatal skin is reduced in 129 strain of mice. Immunology Letters. 81: 211-6. PMID 11947927 DOI: 10.1016/S0165-2478(02)00007-X  0.371
2001 Ye SK, Agata Y, Lee HC, Kurooka H, Kitamura T, Shimizu A, Honjo T, Ikuta K. The IL-7 receptor controls the accessibility of the TCRgamma locus by Stat5 and histone acetylation. Immunity. 15: 813-23. PMID 11728342 DOI: 10.1016/S1074-7613(01)00230-8  0.51
2001 Fagarasan S, Kinoshita K, Muramatsu M, Ikuta K, Honjo T. In situ class switching and differentiation to IgA-producing cells in the gut lamina propria. Nature. 413: 639-43. PMID 11675788 DOI: 10.1038/35098100  0.567
2001 Ye SK, Maki K, Lee HC, Ito A, Kawai K, Suzuki H, Mak TW, Chien Y, Honjo T, Ikuta K. Differential roles of cytokine receptors in the development of epidermal gamma delta T cells. Journal of Immunology (Baltimore, Md. : 1950). 167: 1929-34. PMID 11489972 DOI: 10.4049/Jimmunol.167.4.1929  0.603
2001 Ikuta K, Lee H-, Ye S-. Role of the IL-7 receptor in gamma-delta T cell development. Chemical Immunology. 79: 29-42. PMID 11478153 DOI: 10.1159/000058830  0.449
2001 Ohba Y, Ikuta K, Ogura A, Matsuda J, Mochizuki N, Nagashima K, Kurokawa K, Mayer BJ, Maki K, Miyazaki J, Matsuda M. Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis. The Embo Journal. 20: 3333-41. PMID 11432821 DOI: 10.1093/Emboj/20.13.3333  0.435
2001 Lee HC, Ye SK, Honjo T, Ikuta K. Induction of germline transcription in the human TCR gamma locus by STAT5. Journal of Immunology (Baltimore, Md. : 1950). 167: 320-6. PMID 11418666 DOI: 10.4049/Jimmunol.167.1.320  0.521
2001 Agata Y, Katakai T, Ye SK, Sugai M, Gonda H, Honjo T, Ikuta K, Shimizu A. Histone acetylation determines the developmentally regulated accessibility for T cell receptor gamma gene recombination. The Journal of Experimental Medicine. 193: 873-80. PMID 11283160 DOI: 10.1084/Jem.193.7.873  0.5
2001 Honda K, Nakano H, Yoshida H, Nishikawa S, Rennert P, Ikuta K, Tamechika M, Yamaguchi K, Fukumoto T, Chiba T, Nishikawa SI. Molecular basis for hematopoietic/mesenchymal interaction during initiation of Peyer's patch organogenesis. The Journal of Experimental Medicine. 193: 621-30. PMID 11238592 DOI: 10.1084/Jem.193.5.621  0.48
2001 Watanabe N, Ikuta K, Fagarasan S, Yazumi S, Chiba T, Honjo T. Migration and differentiation of autoreactive B-1 cells induced by activated gamma/delta T cells in antierythrocyte immunoglobulin transgenic mice. The Journal of Experimental Medicine. 192: 1577-86. PMID 11104800 DOI: 10.1084/Jem.192.11.1577  0.636
2000 Fagarasan S, Shinkura R, Kamata T, Nogaki F, Ikuta K, Honjo T. Mechanism of B1 cell differentiation and migration in GALT. Current Topics in Microbiology and Immunology. 252: 221-229. PMID 11125479 DOI: 10.1007/978-3-642-57284-5_23  0.534
2000 O'Brien RL, Yin X, Huber SA, Ikuta K, Born WK. Depletion of a gamma delta T cell subset can increase host resistance to a bacterial infection. Journal of Immunology (Baltimore, Md. : 1950). 165: 6472-9. PMID 11086087 DOI: 10.4049/Jimmunol.165.11.6472  0.448
2000 Kamata T, Nogaki F, Fagarasan S, Sakiyama T, Kobayashi I, Miyawaki S, Ikuta K, Muso E, Yoshida H, Sasayama S, Honjo T. Increased frequency of surface IgA-positive plasma cells in the intestinal lamina propria and decreased IgA excretion in hyper IgA (HIGA) mice, a murine model of IgA nephropathy with hyperserum IgA. Journal of Immunology (Baltimore, Md. : 1950). 165: 1387-94. PMID 10903742 DOI: 10.4049/Jimmunol.165.3.1387  0.529
2000 Kina T, Ikuta K, Takayama E, Wada K, Majumdar AS, Weissman IL, Katsura Y. The monoclonal antibody TER-119 recognizes a molecule associated with glycophorin A and specifically marks the late stages of murine erythroid lineage. British Journal of Haematology. 109: 280-7. PMID 10848813 DOI: 10.1046/J.1365-2141.2000.02037.X  0.552
2000 Fagarasan S, Shinkura R, Kamata T, Nogaki F, Ikuta K, Tashiro K, Honjo T. Alymphoplasia (aly)-type nuclear factor kappaB-inducing kinase (NIK) causes defects in secondary lymphoid tissue chemokine receptor signaling and homing of peritoneal cells to the gut-associated lymphatic tissue system. The Journal of Experimental Medicine. 191: 1477-86. PMID 10790423 DOI: 10.1084/Jem.191.9.1477  0.583
1999 Ye SK, Maki K, Kitamura T, Sunaga S, Akashi K, Domen J, Weissman IL, Honjo T, Ikuta K. Induction of germline transcription in the TCRgamma locus by Stat5: implications for accessibility control by the IL-7 receptor. Immunity. 11: 213-23. PMID 10485656 DOI: 10.1016/S1074-7613(00)80096-5  0.643
1999 Kodaira Y, Ikuta K, Tanaka S, Yokomuro K. Antigen-driven clonal accumulation of peritoneal gammadelta T cells in vivo. Immunological Investigations. 28: 137-48. PMID 10484679 DOI: 10.3109/08820139909061143  0.478
1999 Nosaka T, Kawashima T, Misawa K, Ikuta K, Mui ALF, Kitamura T. STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells Embo Journal. 18: 4754-4765. PMID 10469654 DOI: 10.1093/Emboj/18.17.4754  0.436
1999 Watanabe N, Nisitani S, Ikuta K, Suzuki M, Chiba T, Honjo T. Expression levels of B cell surface immunoglobulin regulate efficiency of allelic exclusion and size of autoreactive B-1 cell compartment. The Journal of Experimental Medicine. 190: 461-69. PMID 10449517 DOI: 10.1084/Jem.190.4.461  0.561
1999 Sakiyama T, Ikuta K, Nisitani S, Takatsu K, Honjo T. Requirement of IL-5 for induction of autoimmune hemolytic anemia in anti-red blood cell autoantibody transgenic mice. International Immunology. 11: 995-1000. PMID 10360974 DOI: 10.1093/Intimm/11.6.995  0.594
1999 Yoshida H, Honda K, Shinkura R, Adachi S, Nishikawa S, Maki K, Ikuta K, Nishikawa SI. IL-7 receptor alpha+ CD3(-) cells in the embryonic intestine induces the organizing center of Peyer's patches. International Immunology. 11: 643-55. PMID 10330270 DOI: 10.1093/Intimm/11.5.643  0.45
1999 Shinkura R, Kitada K, Matsuda F, Tashiro K, Ikuta K, Suzuki M, Kogishi K, Serikawa T, Honjo T. Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase. Nature Genetics. 22: 74-7. PMID 10319865 DOI: 10.1038/8780  0.511
1998 Ishii S, Kuwaki T, Nagase T, Maki K, Tashiro F, Sunaga S, Cao WH, Kume K, Fukuchi Y, Ikuta K, Miyazaki J, Kumada M, Shimizu T. Impaired anaphylactic responses with intact sensitivity to endotoxin in mice lacking a platelet-activating factor receptor. The Journal of Experimental Medicine. 187: 1779-88. PMID 9607919 DOI: 10.1084/Jem.187.11.1779  0.344
1998 Adachi S, Yoshida H, Honda K, Maki K, Saijo K, Ikuta K, Saito T, Nishikawa SI. Essential role of IL-7 receptor alpha in the formation of Peyer's patch anlage. International Immunology. 10: 1-6. PMID 9488150 DOI: 10.1093/intimm/10.1.1  0.326
1998 Uozumi N, Kume K, Nagase T, Nakatani N, Ishii S, Tashiro F, Komagata Y, Maki K, Ikuta K, Ouchi Y, Miyazaki J, Shimizu T. Role of cytosolic phospholipase A2 in allergic response and parturition. Nature. 390: 618-22. PMID 9403692 DOI: 10.1038/37622  0.302
1997 Miyaura C, Onoe Y, Inada M, Maki K, Ikuta K, Ito M, Suda T. Increased B-lymphopoiesis by interleukin 7 induces bone loss in mice with intact ovarian function: similarity to estrogen deficiency. Proceedings of the National Academy of Sciences of the United States of America. 94: 9360-5. PMID 9256487 DOI: 10.1073/Pnas.94.17.9360  0.344
1997 Takeuchi T, Ueki T, Sunaga S, Ikuta K, Sasaki Y, Li B, Moriyama N, Miyazaki J, Kawabe K. Murine interleukin 4 transgenic heart allograft survival prolonged with down-regulation of the Th1 cytokine mRNA in grafts. Transplantation. 64: 152-157. PMID 9233716 DOI: 10.1097/00007890-199707150-00026  0.382
1997 Sunaga S, Maki K, Komagata Y, Ikuta K, Miyazaki JI. Efficient removal of loxP-flanked DNA sequences in a gene-targeted locus by transient expression of Cre recombinase in fertilized eggs. Molecular Reproduction and Development. 46: 109-13. PMID 9021742 DOI: 10.1002/(Sici)1098-2795(199702)46:2<109::Aid-Mrd1>3.0.Co;2-U  0.388
1997 Sunaga S, Maki K, Lagasse E, Blanco JC, Ozato K, Miyazaki J, Ikuta K. Myeloid differentiation is impaired in transgenic mice with targeted expression of a dominant negative form of retinoid X receptor beta. British Journal of Haematology. 96: 19-30. PMID 9012684 DOI: 10.1046/J.1365-2141.1997.8692483.X  0.663
1997 Ishii S, Nagase T, Tashiro F, Ikuta K, Sato S, Waga I, Kume K, Miyazaki J, Shimizu T. Bronchial hyperreactivity, increased endotoxin lethality and melanocytic tumorigenesis in transgenic mice overexpressing platelet-activating factor receptor. The Embo Journal. 16: 133-142. PMID 9009274 DOI: 10.1093/Emboj/16.1.133  0.354
1997 Maki K, Sunaga S, Ikuta K. The V-J recombination of T cell receptor-gamma genes is blocked in interleukin-7 receptor-deficient mice. The Journal of Experimental Medicine. 184: 2423-7. PMID 8976198 DOI: 10.1084/Jem.184.6.2423  0.45
1997 Aoe T, Okamoto Y, Arase H, Ikuta K, Miyazaki J, Ono S, Otuji M, Ohno H, Miyatake S, Saito T. Preferential requirement of CD3 zeta-mediated signals for development of immature rather than mature thymocytes. International Immunology. 8: 1055-66. PMID 8757951 DOI: 10.1093/Intimm/8.7.1055  0.355
1997 Komagata Y, Weissman IL, Ikuta K. Heterogeneity of N insertion capacity in fetal hematopoietic stem cells. International Immunology. 8: 837-45. PMID 8671673 DOI: 10.1093/Intimm/8.6.837  0.502
1996 Kanamori Y, Ishimaru K, Nanno M, Maki K, Ikuta K, Nariuchi H, Ishikawa H. Identification of novel lymphoid tissues in murine intestinal mucosa where clusters of c-kit+ IL-7R+ Thy1+ lympho-hemopoietic progenitors develop. The Journal of Experimental Medicine. 184: 1449-59. PMID 8879216 DOI: 10.1084/JEM.184.4.1449  0.381
1996 Kodaira Y, Yokomuro K, Tanaka S, Miyazaki JI, Ikuta K. Developmental heterogeneity of V gamma 1.1 T cells in the mouse liver. Immunology. 87: 213-9. PMID 8698382 DOI: 10.1046/J.1365-2567.1996.452531.X  0.449
1996 Maki K, Sunaga S, Komagata Y, Kodaira Y, Mabuchi A, Karasuyama H, Yokomuro K, Miyazaki JI, Ikuta K. Interleukin 7 receptor-deficient mice lack gammadelta T cells. Proceedings of the National Academy of Sciences of the United States of America. 93: 7172-7. PMID 8692964 DOI: 10.1073/Pnas.93.14.7172  0.494
1996 Yoshida T, Ikuta K, Sugaya H, Maki K, Takagi M, Kanazawa H, Sunaga S, Kinashi T, Yoshimura K, Miyazaki J, Takaki S, Takatsu K. Defective B-1 cell development and impaired immunity against Angiostrongylus cantonensis in IL-5R alpha-deficient mice. Immunity. 4: 483-94. PMID 8630733 DOI: 10.1016/S1074-7613(00)80414-8  0.432
1995 Ishihara H, Tashiro F, Ikuta K, Asano T, Katagiri H, Inukai K, Kikuchi M, Yazaki Y, Oka Y, Miyazaki J. Inhibition of pancreatic β-cell glucokinase by antisense RNA expression in transgenic mice: mouse strain-dependent alteration of glucose tolerance Febs Letters. 371: 329-332. PMID 7556622 DOI: 10.1016/0014-5793(95)00932-Y  0.301
1993 Fleming WH, Alpern EJ, Uchida N, Ikuta K, Spangrude GJ, Weissman IL. Functional heterogeneity is associated with the cell cycle status of murine hematopoietic stem cells. The Journal of Cell Biology. 122: 897-902. PMID 8349737 DOI: 10.1083/Jcb.122.4.897  0.757
1993 Fleming WH, Alpern EJ, Uchida N, Ikuta K, Weissman IL. Steel factor influences the distribution and activity of murine hematopoietic stem cells in vivo. Proceedings of the National Academy of Sciences of the United States of America. 90: 3760-4. PMID 7682717 DOI: 10.1073/Pnas.90.8.3760  0.73
1993 Ikuta K, Weissman IL. T lymphocyte development from fetal hematopoietic stem cells Seminars in Developmental Biology. 4: 371-378. DOI: 10.1006/Sedb.1993.1041  0.585
1992 Ikuta K, Kina T, MacNeil I, Uchida N, Peault B, Chien YH, Weissman IL. Development of gamma delta T-cell subsets from fetal hematopoietic stem cells. Annals of the New York Academy of Sciences. 651: 21-32. PMID 1599125 DOI: 10.1111/J.1749-6632.1992.Tb24590.X  0.733
1992 Ikuta K, Uchida N, Friedman J, Weissman IL. Lymphocyte development from stem cells. Annual Review of Immunology. 10: 759-83. PMID 1375474 DOI: 10.1146/Annurev.Iy.10.040192.003551  0.749
1992 Ikuta K, Weissman IL. Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation. Proceedings of the National Academy of Sciences of the United States of America. 89: 1502-6. PMID 1371359 DOI: 10.1073/Pnas.89.4.1502  0.567
1991 Spangrude GJ, Smith L, Uchida N, Ikuta K, Heimfeld S, Friedman J, Weissman IL. Mouse hematopoietic stem cells. Blood. 78: 1395-402. PMID 1884012 DOI: 10.1182/Blood.V78.6.1395.Bloodjournal7861395  0.759
1991 Ikuta K, Weissman IL. The junctional modifications of a T cell receptor gamma chain are determined at the level of thymic precursors. The Journal of Experimental Medicine. 174: 1279-82. PMID 1834763 DOI: 10.1084/Jem.174.5.1279  0.549
1991 Ikuta K, Ingolia DE, Friedman J, Heimfeld S, Weissman IL. Mouse hematopoietic stem cells and the interaction of c-kit receptor and steel factor. International Journal of Cell Cloning. 9: 451-60. PMID 1720154 DOI: 10.1002/STEM.1991.5530090503  0.495
1990 Ikuta K, Kina T, MacNeil I, Uchida N, Peault B, Chien YH, Weissman IL. A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells. Cell. 62: 863-74. PMID 1975515 DOI: 10.1016/0092-8674(90)90262-D  0.73
1987 Ikuta K, Takami M, Kim CW, Honjo T, Miyoshi T, Tagaya Y, Kawabe T, Yodoi J. Human lymphocyte Fc receptor for IgE: sequence homology of its cloned cDNA with animal lectins. Proceedings of the National Academy of Sciences of the United States of America. 84: 819-23. PMID 2949326 DOI: 10.1073/Pnas.84.3.819  0.443
1986 Ikuta K, Hattori M, Wake K, Kano S, Honjo T, Yodoi J, Minato N. Expression and rearrangement of the alpha, beta, and gamma chain genes of the T cell receptor in cloned murine large granular lymphocyte lines. No correlation with the cytotoxic spectrum. The Journal of Experimental Medicine. 164: 428-42. PMID 3723079 DOI: 10.1084/Jem.164.2.428  0.508
1986 Ikuta K, Ogura T, Shimizu A, Honjo T. A joining-diversity-joining complex generated by inversion mechanism and a variable-diversity complex in the beta-chain gene of the human T-cell receptor. Nucleic Acids Research. 14: 4899-909. PMID 3487774 DOI: 10.1093/Nar/14.12.4899  0.504
1986 Maeda M, Shimizu A, Ikuta K, Okamoto H, Kashihara M, Uchiyama T, Honjo T, Yodoi J. Origin of human T-lymphotrophic virus I-positive T cell lines in adult T cell leukemia. Analysis of T cell receptor gene rearrangement. The Journal of Experimental Medicine. 162: 2169-74. PMID 2866223 DOI: 10.1084/Jem.162.6.2169  0.61
1985 Ikuta K, Ogura T, Shimizu A, Honjo T. Low frequency of somatic mutation in beta-chain variable region genes of human T-cell receptors. Proceedings of the National Academy of Sciences of the United States of America. 82: 7701-5. PMID 3865189 DOI: 10.1073/Pnas.82.22.7701  0.53
1985 Yodoi J, Okada M, Tagaya Y, Teshigawara K, Fukui K, Ishida N, Ikuta K, Maeda M, Honjo T, Osawa H. Rat lymphoid cell lines producing human T cell leukemia virus. II. Constitutive expression of rat interleukin 2 receptor. The Journal of Experimental Medicine. 161: 924-34. PMID 2985731 DOI: 10.1084/Jem.161.5.924  0.573
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