| Year |
Citation |
Score |
| 2019 |
Indrieri A, Carrella S, Romano A, Spaziano A, Marrocco E, Fernandez-Vizarra E, Barbato S, Pizzo M, Ezhova Y, Golia FM, Ciampi L, Tammaro R, Henao-Mejia J, Williams A, Flavell RA, et al. miR-181a/b downregulation exerts a protective action on mitochondrial disease models. Embo Molecular Medicine. PMID 30979712 DOI: 10.15252/emmm.201708734 |
0.44 |
|
| 2018 |
Shehata HM, Khan S, Chen E, Fields PE, Flavell RA, Sanjabi S. Lack of Sprouty 1 and 2 enhances survival of effector CD8 T cells and yields more protective memory cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 30126987 DOI: 10.1073/pnas.1808320115 |
0.68 |
|
| 2018 |
Stefanski HE, Xing Y, Taylor PA, Maio S, Henao-Meija J, Williams A, Flavell RA, Hollander GA, Blazar BR. Despite high levels of expression in thymic epithelial cells, miR-181a1 and miR-181b1 are not required for thymic development. Plos One. 13: e0198871. PMID 29949604 DOI: 10.1371/journal.pone.0198871 |
0.44 |
|
| 2018 |
Herndler-Brandstetter D, Ishigame H, Shinnakasu R, Plajer V, Stecher C, Zhao J, Lietzenmayer M, Kroehling L, Takumi A, Kometani K, Inoue T, Kluger Y, Kaech SM, Kurosaki T, Okada T, ... Flavell RA, et al. KLRG1 Effector CD8 T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity. Immunity. 48: 716-729.e8. PMID 29625895 DOI: 10.1016/j.immuni.2018.03.015 |
0.44 |
|
| 2018 |
Guan T, Dominguez CX, Amezquita RA, Laidlaw BJ, Cheng J, Henao-Mejia J, Williams A, Flavell RA, Lu J, Kaech SM. ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8T cell fates. The Journal of Experimental Medicine. PMID 29449309 DOI: 10.1084/jem.20171352 |
0.44 |
|
| 2017 |
Kant S, Standen CL, Morel C, Jung DY, Kim JK, Swat W, Flavell RA, Davis RJ. A Protein Scaffold Coordinates SRC-Mediated JNK Activation in Response to Metabolic Stress. Cell Reports. 20: 2775-2783. PMID 28930674 DOI: 10.1016/j.celrep.2017.08.025 |
0.48 |
|
| 2017 |
Mowel WK, McCright SJ, Kotzin JJ, Collet MA, Uyar A, Chen X, DeLaney A, Spencer SP, Virtue AT, Yang E, Villarino A, Kurachi M, Dunagin MC, Pritchard GH, Stein J, ... ... Flavell RA, et al. Group 1 Innate Lymphoid Cell Lineage Identity Is Determined by a cis-Regulatory Element Marked by a Long Non-coding RNA. Immunity. 47: 435-449.e8. PMID 28930659 DOI: 10.1016/j.immuni.2017.08.012 |
0.44 |
|
| 2016 |
Hu B, Jin C, Li HB, Tong J, Ouyang X, Cetinbas NM, Zhu S, Strowig T, Lam FC, Zhao C, Henao-Mejia J, Yilmaz O, Fitzgerald KA, Eisenbarth SC, Elinav E, ... Flavell RA, et al. The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury. Science (New York, N.Y.). 354: 765-768. PMID 27846608 DOI: 10.1126/science.aaf7532 |
0.44 |
|
| 2016 |
Paul AM, Acharya D, Le L, Wang P, Stokic DS, Leis AA, Alexopoulou L, Town T, Flavell RA, Fikrig E, Bai F. TLR8 Couples SOCS-1 and Restrains TLR7-Mediated Antiviral Immunity, Exacerbating West Nile Virus Infection in Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 27798161 DOI: 10.4049/jimmunol.1600902 |
0.64 |
|
| 2016 |
Acharya D, Wang P, Paul AM, Dai J, Gate D, Lowery JE, Stokic DS, Leis AA, Flavell RA, Town T, Fikrig E, Bai F. Interleukin-17A Promotes CD8+ T Cell Cytotoxicity to Facilitate West Nile Virus Clearance. Journal of Virology. PMID 27795421 DOI: 10.1128/JVI.01529-16 |
0.64 |
|
| 2016 |
Shen X, Burguillos MA, Osman AM, Frijhoff J, Carrillo-Jiménez A, Kanatani S, Augsten M, Saidi D, Rodhe J, Kavanagh E, Rongvaux A, Rraklli V, Nyman U, Holmberg J, Östman A, ... Flavell RA, et al. Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype. Nature Immunology. PMID 27618552 DOI: 10.1038/ni.3545 |
1 |
|
| 2016 |
Boddupalli CS, Nair S, Gray SM, Nowyhed HN, Verma R, Gibson JA, Abraham C, Narayan D, Vasquez J, Hedrick CC, Flavell RA, Dhodapkar KM, Kaech SM, Dhodapkar MV. ABC transporters and NR4A1 identify a quiescent subset of tissue-resident memory T cells. The Journal of Clinical Investigation. PMID 27617863 DOI: 10.1172/JCI85329 |
1 |
|
| 2016 |
Weinstein JS, Herman EI, Lainez B, Licona-Limón P, Esplugues E, Flavell R, Craft J. TFH cells progressively differentiate to regulate the germinal center response. Nature Immunology. PMID 27573866 DOI: 10.1038/ni.3554 |
1 |
|
| 2016 |
Kotzin JJ, Spencer SP, McCright SJ, Kumar DB, Collet MA, Mowel WK, Elliott EN, Uyar A, Makiya MA, Dunagin MC, Harman CC, Virtue AT, Zhu S, Bailis W, Stein J, ... ... Flavell RA, et al. The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan. Nature. PMID 27525555 DOI: 10.1038/nature19346 |
1 |
|
| 2016 |
Costa FR, Françozo MC, de Oliveira GG, Ignacio A, Castoldi A, Zamboni DS, Ramos SG, Câmara NO, de Zoete MR, Palm NW, Flavell RA, Silva JS, Carlos D. Gut microbiota translocation to the pancreatic lymph nodes triggers NOD2 activation and contributes to T1D onset. The Journal of Experimental Medicine. PMID 27325889 DOI: 10.1084/jem.20150744 |
1 |
|
| 2016 |
Krebs CF, Turner JE, Paust HJ, Kapffer S, Koyro T, Krohn S, Ufer F, Friese MA, Flavell RA, Stockinger B, Steinmetz OM, Stahl RA, Huber S, Panzer U. Plasticity of Th17 Cells in Autoimmune Kidney Diseases. Journal of Immunology (Baltimore, Md. : 1950). PMID 27271566 DOI: 10.4049/jimmunol.1501831 |
1 |
|
| 2016 |
Hwang SS, Kim LK, Lee GR, Flavell RA. Role of OCT-1 and partner proteins in T cell differentiation. Biochimica Et Biophysica Acta. PMID 27126747 DOI: 10.1016/j.bbagrm.2016.04.006 |
1 |
|
| 2016 |
Pillai PS, Molony RD, Martinod K, Dong H, Pang IK, Tal MC, Solis AG, Bielecki P, Mohanty S, Trentalange M, Homer RJ, Flavell RA, Wagner DD, Montgomery RR, Shaw AC, et al. Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease. Science (New York, N.Y.). 352: 463-6. PMID 27102485 DOI: 10.1126/science.aaf3926 |
1 |
|
| 2016 |
Chan PY, Carrera Silva EA, De Kouchkovsky D, Joannas LD, Hao L, Hu D, Huntsman S, Eng C, Licona-Limón P, Weinstein JS, Herbert DR, Craft JE, Flavell RA, Repetto S, Correale J, et al. The TAM family receptor tyrosine kinase TYRO3 is a negative regulator of type 2 immunity. Science (New York, N.Y.). 352: 99-103. PMID 27034374 DOI: 10.1126/science.aaf1358 |
1 |
|
| 2016 |
Cheng J, Roden CA, Pan W, Zhu S, Baccei A, Pan X, Jiang T, Kluger Y, Weissman SM, Guo S, Flavell RA, Ding Y, Lu J. A Molecular Chipper technology for CRISPR sgRNA library generation and functional mapping of noncoding regions. Nature Communications. 7: 11178. PMID 27025950 DOI: 10.1038/ncomms11178 |
1 |
|
| 2016 |
Vernia S, Morel C, Madara JC, Cavanagh-Kyros J, Barrett T, Chase K, Kennedy NJ, Jung DY, Kim JK, Aronin N, Flavell RA, Lowell BB, Davis RJ. Excitatory transmission onto AgRP neurons is regulated by cJun NH2-terminal kinase 3 in response to metabolic stress. Elife. 5. PMID 26910012 DOI: 10.7554/eLife.10031 |
1 |
|
| 2016 |
Hwang SS, Jang SW, Kim MK, Kim LK, Kim BS, Kim HS, Kim K, Lee W, Flavell RA, Lee GR. YY1 inhibits differentiation and function of regulatory T cells by blocking Foxp3 expression and activity. Nature Communications. 7: 10789. PMID 26892542 DOI: 10.1038/ncomms10789 |
0.76 |
|
| 2016 |
Williams A, Henao-Mejia J, Flavell RA. Editing the Mouse Genome Using the CRISPR-Cas9 System. Cold Spring Harbor Protocols. 2016: pdb.top087536. PMID 26832693 DOI: 10.1101/pdb.top087536 |
1 |
|
| 2016 |
Henao-Mejia J, Williams A, Rongvaux A, Stein J, Hughes C, Flavell RA. Generation of Genetically Modified Mice Using the CRISPR-Cas9 Genome-Editing System. Cold Spring Harbor Protocols. 2016: pdb.prot090704. PMID 26832688 DOI: 10.1101/pdb.prot090704 |
1 |
|
| 2016 |
Matza D, Badou A, Klemic KG, Stein J, Govindarajulu U, Nadler MJ, Kinet JP, Peled A, Shapira OM, Kaczmarek LK, Flavell RA. T Cell Receptor Mediated Calcium Entry Requires Alternatively Spliced Cav1.1 Channels. Plos One. 11: e0147379. PMID 26815481 DOI: 10.1371/journal.pone.0147379 |
1 |
|
| 2015 |
Hong E, Usiskin IM, Bergamaschi C, Hanlon DJ, Edelson RL, Justesen S, Pavlakis GN, Flavell RA, Fahmy TM. Configuration-dependent presentation of multivalent IL-15:IL-15Rα enhances the antigen-specific T cell response and anti-tumor immunity. The Journal of Biological Chemistry. PMID 26719339 DOI: 10.1074/jbc.M115.695304 |
1 |
|
| 2015 |
Nowarski R, Jackson R, Gagliani N, de Zoete MR, Palm NW, Bailis W, Low JS, Harman CC, Graham M, Elinav E, Flavell RA. Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis. Cell. 163: 1444-56. PMID 26638073 DOI: 10.1016/j.cell.2015.10.072 |
1 |
|
| 2015 |
Levy M, Thaiss CA, Zeevi D, Dohnalová L, Zilberman-Schapira G, Mahdi JA, David E, Savidor A, Korem T, Herzig Y, Pevsner-Fischer M, Shapiro H, Christ A, Harmelin A, Halpern Z, ... ... Flavell RA, et al. Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling. Cell. 163: 1428-43. PMID 26638072 DOI: 10.1016/j.cell.2015.10.048 |
0.76 |
|
| 2015 |
Paterka M, Siffrin V, Voss JO, Werr J, Hoppmann N, Gollan R, Belikan P, Bruttger J, Birkenstock J, Jung S, Esplugues E, Yogev N, Flavell RA, Bopp T, Zipp F. Gatekeeper role of brain antigen-presenting CD11c+ cells in neuroinflammation. The Embo Journal. PMID 26612827 DOI: 10.15252/embj.201591488 |
0.76 |
|
| 2015 |
Eisenbarth SC, Williams A, Colegio OR, Meng H, Strowig T, Rongvaux A, Henao-Mejia J, Thaiss CA, Joly S, Gonzalez DG, Xu L, Zenewicz LA, Haberman AM, Elinav E, Kleinstein SH, ... ... Flavell RA, et al. Corrigendum: NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells. Nature. PMID 26605525 DOI: 10.1038/nature16074 |
0.6 |
|
| 2015 |
Wang P, Zhu S, Yang L, Cui S, Pan W, Jackson R, Zheng Y, Rongvaux A, Sun Q, Yang G, Gao S, Lin R, You F, Flavell R, Fikrig E. Nlrp6 regulates intestinal antiviral innate immunity. Science (New York, N.Y.). PMID 26494172 DOI: 10.1126/science.aab3145 |
1 |
|
| 2015 |
Jha A, Singh AK, Weissgerber P, Freichel M, Flockerzi V, Flavell RA, Jha MK. Essential roles for Cavβ2 and Cav1 channels in thymocyte development and T cell homeostasis. Science Signaling. 8: ra103. PMID 26486172 DOI: 10.1126/scisignal.aac7538 |
1 |
|
| 2015 |
Finethy R, Jorgensen I, Haldar AK, de Zoete MR, Strowig T, Flavell RA, Yamamoto M, Nagarajan UM, Miao EA, Coers J. Guanylate Binding Proteins Enable Rapid Activation of Canonical and Noncanonical Inflammasomes in Chlamydia-Infected Macrophages. Infection and Immunity. 83: 4740-9. PMID 26416908 DOI: 10.1128/IAI.00856-15 |
1 |
|
| 2015 |
Hu C, Ding H, Li Y, Pearson JA, Zhang X, Flavell RA, Wong FS, Wen L. NLRP3 deficiency protects from type 1 diabetes through the regulation of chemotaxis into the pancreatic islets. Proceedings of the National Academy of Sciences of the United States of America. PMID 26305961 DOI: 10.1073/pnas.1513509112 |
1 |
|
| 2015 |
Thiele K, Solano ME, Huber S, Flavell RA, Kessler T, Barikbin R, Jung R, Karimi K, Tiegs G, Arck PC. Prenatal Acetaminophen Affects Maternal Immune and Endocrine Adaptation to Pregnancy, Induces Placental Damage, and Impairs Fetal Development in Mice. The American Journal of Pathology. PMID 26254283 DOI: 10.1016/j.ajpath.2015.06.019 |
0.76 |
|
| 2015 |
Jones A, Opejin A, Henderson JG, Gross C, Jain R, Epstein JA, Flavell RA, Hawiger D. Peripherally Induced Tolerance Depends on Peripheral Regulatory T Cells That Require Hopx To Inhibit Intrinsic IL-2 Expression. Journal of Immunology (Baltimore, Md. : 1950). PMID 26170384 DOI: 10.4049/jimmunol.1500174 |
0.76 |
|
| 2015 |
Laidlaw BJ, Cui W, Amezquita RA, Gray SM, Guan T, Lu Y, Kobayashi Y, Flavell RA, Kleinstein SH, Craft J, Kaech SM. Production of IL-10 by CD4(+) regulatory T cells during the resolution of infection promotes the maturation of memory CD8(+) T cells. Nature Immunology. PMID 26147684 DOI: 10.1038/ni.3224 |
0.76 |
|
| 2015 |
Palm NW, de Zoete MR, Flavell RA. Immune-microbiota interactions in health and disease. Clinical Immunology (Orlando, Fla.). 159: 122-7. PMID 26141651 DOI: 10.1016/j.clim.2015.05.014 |
1 |
|
| 2015 |
Cardona M, López JA, Serafín A, Rongvaux A, Inserte J, García-Dorado D, Flavell R, Llovera M, Cañas X, Vázquez J, Sanchis D. Executioner Caspase-3 and 7 Deficiency Reduces Myocyte Number in the Developing Mouse Heart. Plos One. 10: e0131411. PMID 26121671 DOI: 10.1371/journal.pone.0131411 |
0.76 |
|
| 2015 |
Kim LK, Morita R, Kobayashi Y, Eisenbarth SC, Lee CG, Elias J, Eynon EE, Flavell RA. AMCase is a crucial regulator of type 2 immune responses to inhaled house dust mites. Proceedings of the National Academy of Sciences of the United States of America. 112: E2891-9. PMID 26038565 DOI: 10.1073/pnas.1507393112 |
1 |
|
| 2015 |
Pan W, Zhu S, Dai D, Liu Z, Li D, Li B, Gagliani N, Zheng Y, Tang Y, Weirauch MT, Chen X, Zhu W, Wang Y, Chen B, Qian Y, ... ... Flavell RA, et al. MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis. Nature Communications. 6: 7096. PMID 25963922 DOI: 10.1038/ncomms8096 |
1 |
|
| 2015 |
Gagliani N, Vesely MC, Iseppon A, Brockmann L, Xu H, Palm NW, de Zoete MR, Licona-Limón P, Paiva RS, Ching T, Weaver C, Zi X, Pan X, Fan R, Garmire LX, ... ... Flavell RA, et al. Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation. Nature. 523: 221-5. PMID 25924064 DOI: 10.1038/nature14452 |
1 |
|
| 2015 |
Zhang Y, Nguyen T, Tang P, Kennedy NJ, Jiao H, Zhang M, Reynolds JM, Jaeschke A, Martin-Orozco N, Chung Y, He WM, Wang C, Jia W, Ge B, Davis RJ, ... Flavell RA, et al. Regulation of Adipose Tissue Inflammation and Insulin Resistance by MAPK Phosphatase 5. The Journal of Biological Chemistry. 290: 14875-83. PMID 25922079 DOI: 10.1074/jbc.M115.660969 |
1 |
|
| 2015 |
. Retraction for Theivanthiran et al., NOD2 signaling contributes to host defense in the lungs against Escherichia coli infection. Infection and Immunity. 83: 2199. PMID 25878164 DOI: 10.1128/IAI.00200-15 |
1 |
|
| 2015 |
Willinger T, Staron M, Ferguson SM, De Camilli P, Flavell RA. Dynamin 2-dependent endocytosis sustains T-cell receptor signaling and drives metabolic reprogramming in T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 112: 4423-8. PMID 25831514 DOI: 10.1073/pnas.1504279112 |
1 |
|
| 2015 |
Macia L, Tan J, Vieira AT, Leach K, Stanley D, Luong S, Maruya M, Ian McKenzie C, Hijikata A, Wong C, Binge L, Thorburn AN, Chevalier N, Ang C, Marino E, ... ... Flavell RA, et al. Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome. Nature Communications. 6: 6734. PMID 25828455 DOI: 10.1038/ncomms7734 |
1 |
|
| 2015 |
James SJ, Jiao H, Teh HY, Takahashi H, Png CW, Phoon MC, Suzuki Y, Sawasaki T, Xiao H, Chow VT, Yamamoto N, Reynolds JM, Flavell RA, Dong C, Zhang Y. MAPK Phosphatase 5 Expression Induced by Influenza and Other RNA Virus Infection Negatively Regulates IRF3 Activation and Type I Interferon Response. Cell Reports. PMID 25772359 DOI: 10.1016/j.celrep.2015.02.030 |
1 |
|
| 2015 |
Zorca CE, Kim LK, Kim YJ, Krause MR, Zenklusen D, Spilianakis CG, Flavell RA. Myosin VI regulates gene pairing and transcriptional pause release in T cells. Proceedings of the National Academy of Sciences of the United States of America. 112: E1587-93. PMID 25770220 DOI: 10.1073/pnas.1502461112 |
1 |
|
| 2015 |
Stratigi K, Kapsetaki M, Aivaliotis M, Town T, Flavell RA, Spilianakis CG. Spatial proximity of homologous alleles and long noncoding RNAs regulate a switch in allelic gene expression. Proceedings of the National Academy of Sciences of the United States of America. 112: E1577-86. PMID 25770217 DOI: 10.1073/pnas.1502182112 |
0.64 |
|
| 2015 |
Krishnaswamy JK, Singh A, Gowthaman U, Wu R, Gorrepati P, Sales Nascimento M, Gallman A, Liu D, Rhebergen AM, Calabro S, Xu L, Ranney P, Srivastava A, Ranson M, Gorham JD, ... ... Flavell RA, et al. Coincidental loss of DOCK8 function in NLRP10-deficient and C3H/HeJ mice results in defective dendritic cell migration. Proceedings of the National Academy of Sciences of the United States of America. 112: 3056-61. PMID 25713392 DOI: 10.1073/pnas.1501554112 |
1 |
|
| 2015 |
Ballinger MN, Newstead MW, Zeng X, Bhan U, Mo XM, Kunkel SL, Moore BB, Flavell R, Christman JW, Standiford TJ. IRAK-M promotes alternative macrophage activation and fibroproliferation in bleomycin-induced lung injury. Journal of Immunology (Baltimore, Md. : 1950). 194: 1894-904. PMID 25595781 DOI: 10.4049/jimmunol.1402377 |
1 |
|
| 2015 |
Deng K, Pertea M, Rongvaux A, Wang L, Durand CM, Ghiaur G, Lai J, McHugh HL, Hao H, Zhang H, Margolick JB, Gurer C, Murphy AJ, Valenzuela DM, Yancopoulos GD, ... ... Flavell RA, et al. Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations. Nature. 517: 381-5. PMID 25561180 DOI: 10.1038/nature14053 |
1 |
|
| 2015 |
Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, Alnemri ES, Altucci L, Andrews D, Annicchiarico-Petruzzelli M, Baehrecke EH, Bazan NG, Bertrand MJ, Bianchi K, Blagosklonny MV, ... ... Flavell RA, et al. Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death and Differentiation. 22: 58-73. PMID 25236395 DOI: 10.1038/cdd.2014.137 |
0.76 |
|
| 2014 |
Rongvaux A, Jackson R, Harman CC, Li T, West AP, de Zoete MR, Wu Y, Yordy B, Lakhani SA, Kuan CY, Taniguchi T, Shadel GS, Chen ZJ, Iwasaki A, Flavell RA. Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA. Cell. 159: 1563-77. PMID 25525875 DOI: 10.1016/j.cell.2014.11.037 |
1 |
|
| 2014 |
Heisig M, Abraham NM, Liu L, Neelakanta G, Mattessich S, Sultana H, Shang Z, Ansari JM, Killiam C, Walker W, Cooley L, Flavell RA, Agaisse H, Fikrig E. Antivirulence properties of an antifreeze protein. Cell Reports. 9: 417-24. PMID 25373896 DOI: 10.1016/j.celrep.2014.09.034 |
1 |
|
| 2014 |
Wegiel B, Larsen R, Gallo D, Chin BY, Harris C, Mannam P, Kaczmarek E, Lee PJ, Zuckerbraun BS, Flavell R, Soares MP, Otterbein LE. Macrophages sense and kill bacteria through carbon monoxide-dependent inflammasome activation. The Journal of Clinical Investigation. 124: 4926-40. PMID 25295542 DOI: 10.1172/JCI72853 |
1 |
|
| 2014 |
Camirand G, Wang Y, Lu Y, Wan YY, Lin Y, Deng S, Guz G, Perkins DL, Finn PW, Farber DL, Flavell RA, Shlomchik WD, Lakkis FG, Rudd CE, Rothstein DM. CD45 ligation expands Tregs by promoting interactions with DCs. The Journal of Clinical Investigation. 124: 4603-13. PMID 25202978 DOI: 10.1172/JCI74087 |
1 |
|
| 2014 |
Palm NW, de Zoete MR, Cullen TW, Barry NA, Stefanowski J, Hao L, Degnan PH, Hu J, Peter I, Zhang W, Ruggiero E, Cho JH, Goodman AL, Flavell RA. Immunoglobulin A coating identifies colitogenic bacteria in inflammatory bowel disease. Cell. 158: 1000-10. PMID 25171403 DOI: 10.1016/j.cell.2014.08.006 |
1 |
|
| 2014 |
Shulman Z, Gitlin AD, Weinstein JS, Lainez B, Esplugues E, Flavell RA, Craft JE, Nussenzweig MC. Dynamic signaling by T follicular helper cells during germinal center B cell selection. Science (New York, N.Y.). 345: 1058-62. PMID 25170154 DOI: 10.1126/science.1257861 |
1 |
|
| 2014 |
Gate D, Danielpour M, Rodriguez J, Kim GB, Levy R, Bannykh S, Breunig JJ, Kaech SM, Flavell RA, Town T. T-cell TGF-β signaling abrogation restricts medulloblastoma progression. Proceedings of the National Academy of Sciences of the United States of America. 111: E3458-66. PMID 25082897 DOI: 10.1073/pnas.1412489111 |
1 |
|
| 2014 |
Chung LK, Philip NH, Schmidt VA, Koller A, Strowig T, Flavell RA, Brodsky IE, Bliska JB. IQGAP1 is important for activation of caspase-1 in macrophages and is targeted by Yersinia pestis type III effector YopM. Mbio. 5: e01402-14. PMID 24987096 DOI: 10.1128/mBio.01402-14 |
1 |
|
| 2014 |
Gagliani N, Palm NW, de Zoete MR, Flavell RA. Inflammasomes and intestinal homeostasis: regulating and connecting infection, inflammation and the microbiota. International Immunology. 26: 495-9. PMID 24948595 DOI: 10.1093/intimm/dxu066 |
1 |
|
| 2014 |
Sheppard NC, Brinckmann SA, Gartlan KH, Puthia M, Svanborg C, Krashias G, Eisenbarth SC, Flavell RA, Sattentau QJ, Wegmann F. Polyethyleneimine is a potent systemic adjuvant for glycoprotein antigens. International Immunology. 26: 531-8. PMID 24844701 DOI: 10.1093/intimm/dxu055 |
1 |
|
| 2014 |
Canaan A, DeFuria J, Perelman E, Schultz V, Seay M, Tuck D, Flavell RA, Snyder MP, Obin MS, Weissman SM. Extended lifespan and reduced adiposity in mice lacking the FAT10 gene. Proceedings of the National Academy of Sciences of the United States of America. 111: 5313-8. PMID 24706839 DOI: 10.1073/pnas.1323426111 |
1 |
|
| 2014 |
Wynosky-Dolfi MA, Snyder AG, Philip NH, Doonan PJ, Poffenberger MC, Avizonis D, Zwack EE, Riblett AM, Hu B, Strowig T, Flavell RA, Jones RG, Freedman BD, Brodsky IE. Oxidative metabolism enables Salmonella evasion of the NLRP3 inflammasome. The Journal of Experimental Medicine. 211: 653-68. PMID 24638169 DOI: 10.1084/jem.20130627 |
1 |
|
| 2014 |
Willinger T, Ferguson SM, Pereira JP, De Camilli P, Flavell RA. Dynamin 2-dependent endocytosis is required for sustained S1PR1 signaling. The Journal of Experimental Medicine. 211: 685-700. PMID 24638168 DOI: 10.1084/jem.20131343 |
1 |
|
| 2014 |
Kim LK, Esplugues E, Zorca CE, Parisi F, Kluger Y, Kim TH, Galjart NJ, Flavell RA. Oct-1 regulates IL-17 expression by directing interchromosomal associations in conjunction with CTCF in T cells. Molecular Cell. 54: 56-66. PMID 24613343 DOI: 10.1016/j.molcel.2014.02.004 |
1 |
|
| 2014 |
Wu X, Lahiri A, Haines GK, Flavell RA, Abraham C. NOD2 regulates CXCR3-dependent CD8+ T cell accumulation in intestinal tissues with acute injury. Journal of Immunology (Baltimore, Md. : 1950). 192: 3409-18. PMID 24591373 DOI: 10.4049/jimmunol.1302436 |
1 |
|
| 2014 |
Wlodarska M, Thaiss CA, Nowarski R, Henao-Mejia J, Zhang JP, Brown EM, Frankel G, Levy M, Katz MN, Philbrick WM, Elinav E, Finlay BB, Flavell RA. NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion. Cell. 156: 1045-59. PMID 24581500 DOI: 10.1016/j.cell.2014.01.026 |
1 |
|
| 2014 |
Huang W, Kachapati K, Adams D, Wu Y, Leung PS, Yang GX, Zhang W, Ansari AA, Flavell RA, Gershwin ME, Ridgway WM. Murine autoimmune cholangitis requires two hits: cytotoxic KLRG1(+) CD8 effector cells and defective T regulatory cells. Journal of Autoimmunity. 50: 123-34. PMID 24556277 DOI: 10.1016/j.jaut.2014.01.034 |
0.32 |
|
| 2014 |
Hacisuleyman E, Goff LA, Trapnell C, Williams A, Henao-Mejia J, Sun L, McClanahan P, Hendrickson DG, Sauvageau M, Kelley DR, Morse M, Engreitz J, Lander ES, Guttman M, Lodish HF, ... Flavell R, et al. Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre. Nature Structural & Molecular Biology. 21: 198-206. PMID 24463464 DOI: 10.1038/nsmb.2764 |
1 |
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| 2014 |
Henao-Mejia J, Elinav E, Thaiss CA, Flavell RA. Inflammasomes and metabolic disease. Annual Review of Physiology. 76: 57-78. PMID 24274736 DOI: 10.1146/annurev-physiol-021113-170324 |
1 |
|
| 2014 |
Liang X, Fu C, Cui W, Ober-Blöbaum JL, Zahner SP, Shrikant PA, Clausen BE, Flavell RA, Mellman I, Jiang A. β-catenin mediates tumor-induced immunosuppression by inhibiting cross-priming of CD8⺠T cells. Journal of Leukocyte Biology. 95: 179-90. PMID 24023259 DOI: 10.1189/jlb.0613330 |
1 |
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| 2013 |
Negishi H, Matsuki K, Endo N, Sarashina H, Miki S, Matsuda A, Fukazawa K, Taguchi-Atarashi N, Ikushima H, Yanai H, Nishio J, Honda K, Fujioka Y, Ohba Y, Noda T, ... ... Flavell RA, et al. Beneficial innate signaling interference for antibacterial responses by a Toll-like receptor-mediated enhancement of the MKP-IRF3 axis. Proceedings of the National Academy of Sciences of the United States of America. 110: 19884-9. PMID 24248350 DOI: 10.1073/pnas.1320145110 |
1 |
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| 2013 |
Richter K, Perriard G, Behrendt R, Schwendener RA, Sexl V, Dunn R, Kamanaka M, Flavell RA, Roers A, Oxenius A. Macrophage and T cell produced IL-10 promotes viral chronicity. Plos Pathogens. 9: e1003735. PMID 24244162 DOI: 10.1371/journal.ppat.1003735 |
1 |
|
| 2013 |
Williams A, Henao-Mejia J, Harman CC, Flavell RA. miR-181 and metabolic regulation in the immune system. Cold Spring Harbor Symposia On Quantitative Biology. 78: 223-30. PMID 24163395 DOI: 10.1101/sqb.2013.78.020024 |
0.44 |
|
| 2013 |
Elinav E, Nowarski R, Thaiss CA, Hu B, Jin C, Flavell RA. Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms. Nature Reviews. Cancer. 13: 759-71. PMID 24154716 DOI: 10.1038/nrc3611 |
1 |
|
| 2013 |
Henao-Mejia J, Elinav E, Thaiss CA, Licona-Limon P, Flavell RA. Role of the intestinal microbiome in liver disease. Journal of Autoimmunity. 46: 66-73. PMID 24075647 DOI: 10.1016/j.jaut.2013.07.001 |
1 |
|
| 2013 |
Chen X, Wen T, Wei J, Wu Z, Wang P, Hong Z, Zhao L, Wang B, Flavell R, Gao S, Wang M, Yin Z. Treatment of allergic inflammation and hyperresponsiveness by a simple compound, Bavachinin, isolated from Chinese herbs. Cellular & Molecular Immunology. 10: 497-505. PMID 24013845 DOI: 10.1038/cmi.2013.27 |
0.36 |
|
| 2013 |
Gisterå A, Robertson AK, Andersson J, Ketelhuth DF, Ovchinnikova O, Nilsson SK, Lundberg AM, Li MO, Flavell RA, Hansson GK. Transforming growth factor-β signaling in T cells promotes stabilization of atherosclerotic plaques through an interleukin-17-dependent pathway. Science Translational Medicine. 5: 196ra100. PMID 23903754 DOI: 10.1126/scitranslmed.3006133 |
1 |
|
| 2013 |
Geldhoff M, Mook-Kanamori BB, Brouwer MC, Troost D, Leemans JC, Flavell RA, Van der Ende A, Van der Poll T, Van de Beek D. Inflammasome activation mediates inflammation and outcome in humans and mice with pneumococcal meningitis. Bmc Infectious Diseases. 13: 358. PMID 23902681 DOI: 10.1186/1471-2334-13-358 |
1 |
|
| 2013 |
Elinav E, Thaiss CA, Flavell RA. Analysis of microbiota alterations in inflammasome-deficient mice. Methods in Molecular Biology (Clifton, N.J.). 1040: 185-94. PMID 23852605 DOI: 10.1007/978-1-62703-523-1_14 |
1 |
|
| 2013 |
Gagliani N, Jofra T, Valle A, Stabilini A, Morsiani C, Gregori S, Deng S, Rothstein DM, Atkinson M, Kamanaka M, Flavell RA, Roncarolo MG, Battaglia M. Transplant tolerance to pancreatic islets is initiated in the graft and sustained in the spleen. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 13: 1963-75. PMID 23834659 DOI: 10.1111/ajt.12333 |
1 |
|
| 2013 |
Zhao Y, Zhao H, Sun Y, Hao J, Qi X, Zhou X, Wu Z, Wang P, Kaech SM, Weaver CT, Flavell RA, Zhao L, Yao Z, Yin Z. IL-4 induces a suppressive IL-10-producing CD8+ T cell population via a Cdkn2a-dependent mechanism. Journal of Leukocyte Biology. 94: 1103-12. PMID 23772040 DOI: 10.1189/jlb.0213064 |
1 |
|
| 2013 |
Casson CN, Copenhaver AM, Zwack EE, Nguyen HT, Strowig T, Javdan B, Bradley WP, Fung TC, Flavell RA, Brodsky IE, Shin S. Caspase-11 activation in response to bacterial secretion systems that access the host cytosol. Plos Pathogens. 9: e1003400. PMID 23762026 DOI: 10.1371/journal.ppat.1003400 |
1 |
|
| 2013 |
Lima-Junior DS, Costa DL, Carregaro V, Cunha LD, Silva AL, Mineo TW, Gutierrez FR, Bellio M, Bortoluci KR, Flavell RA, Bozza MT, Silva JS, Zamboni DS. Inflammasome-derived IL-1β production induces nitric oxide-mediated resistance to Leishmania. Nature Medicine. 19: 909-15. PMID 23749230 DOI: 10.1038/nm.3221 |
1 |
|
| 2013 |
Knauf F, Asplin JR, Granja I, Schmidt IM, Moeckel GW, David RJ, Flavell RA, Aronson PS. NALP3-mediated inflammation is a principal cause of progressive renal failure in oxalate nephropathy. Kidney International. 84: 895-901. PMID 23739234 DOI: 10.1038/ki.2013.207 |
1 |
|
| 2013 |
Hu B, Elinav E, Huber S, Strowig T, Hao L, Hafemann A, Jin C, Wunderlich C, Wunderlich T, Eisenbarth SC, Flavell RA. Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer. Proceedings of the National Academy of Sciences of the United States of America. 110: 9862-7. PMID 23696660 DOI: 10.1073/pnas.1307575110 |
0.44 |
|
| 2013 |
Licona-Limón P, Kim LK, Palm NW, Flavell RA. TH2, allergy and group 2 innate lymphoid cells. Nature Immunology. 14: 536-42. PMID 23685824 DOI: 10.1038/ni.2617 |
1 |
|
| 2013 |
Henao-Mejia J, Williams A, Goff LA, Staron M, Licona-Limón P, Kaech SM, Nakayama M, Rinn JL, Flavell RA. The microRNA miR-181 is a critical cellular metabolic rheostat essential for NKT cell ontogenesis and lymphocyte development and homeostasis. Immunity. 38: 984-97. PMID 23623381 DOI: 10.1016/j.immuni.2013.02.021 |
1 |
|
| 2013 |
Henao-Mejia J, Elinav E, Thaiss CA, Flavell RA. The intestinal microbiota in chronic liver disease. Advances in Immunology. 117: 73-97. PMID 23611286 DOI: 10.1016/B978-0-12-410524-9.00003-7 |
1 |
|
| 2013 |
Zenewicz LA, Yin X, Wang G, Elinav E, Hao L, Zhao L, Flavell RA. IL-22 deficiency alters colonic microbiota to be transmissible and colitogenic. Journal of Immunology (Baltimore, Md. : 1950). 190: 5306-12. PMID 23585682 DOI: 10.4049/jimmunol.1300016 |
0.6 |
|
| 2013 |
Williams A, Lee GR, Spilianakis CG, Hwang SS, Eisenbarth SC, Flavell RA. Hypersensitive site 6 of the Th2 locus control region is essential for Th2 cytokine expression. Proceedings of the National Academy of Sciences of the United States of America. 110: 6955-60. PMID 23569250 DOI: 10.1073/pnas.1304720110 |
0.76 |
|
| 2013 |
Ishigame H, Zenewicz LA, Sanjabi S, Licona-Limón P, Nakayama M, Leonard WJ, Flavell RA. Excessive Th1 responses due to the absence of TGF-β signaling cause autoimmune diabetes and dysregulated Treg cell homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 110: 6961-6. PMID 23569233 DOI: 10.1073/pnas.1304498110 |
0.6 |
|
| 2013 |
Lawrence TM, Hudacek AW, de Zoete MR, Flavell RA, Schnell MJ. Rabies virus is recognized by the NLRP3 inflammasome and activates interleukin-1β release in murine dendritic cells. Journal of Virology. 87: 5848-57. PMID 23487464 DOI: 10.1128/JVI.00203-13 |
1 |
|
| 2013 |
Ye J, Llorian M, Cardona M, Rongvaux A, Moubarak RS, Comella JX, Bassel-Duby R, Flavell RA, Olson EN, Smith CW, Sanchis D. A pathway involving HDAC5, cFLIP and caspases regulates expression of the splicing regulator polypyrimidine tract binding protein in the heart. Journal of Cell Science. 126: 1682-91. PMID 23424201 DOI: 10.1242/jcs.121384 |
1 |
|
| 2013 |
Martin RA, Ather JL, Lundblad LK, Suratt BT, Boyson JE, Budd RC, Alcorn JF, Flavell RA, Eisenbarth SC, Poynter ME. Interleukin-1 receptor and caspase-1 are required for the Th17 response in nitrogen dioxide-promoted allergic airway disease. American Journal of Respiratory Cell and Molecular Biology. 48: 655-64. PMID 23371061 DOI: 10.1165/rcmb.2012-0423OC |
1 |
|
| 2013 |
Chaiyachati BH, Jani A, Wan Y, Huang H, Flavell R, Chi T. BRG1-mediated immune tolerance: facilitation of Treg activation and partial independence of chromatin remodelling. The Embo Journal. 32: 395-408. PMID 23321680 DOI: 10.1038/emboj.2012.350 |
1 |
|
| 2013 |
Case CL, Kohler LJ, Lima JB, Strowig T, de Zoete MR, Flavell RA, Zamboni DS, Roy CR. Caspase-11 stimulates rapid flagellin-independent pyroptosis in response to Legionella pneumophila. Proceedings of the National Academy of Sciences of the United States of America. 110: 1851-6. PMID 23307811 DOI: 10.1073/pnas.1211521110 |
1 |
|
| 2013 |
Terwagne M, Ferooz J, Rolán HG, Sun YH, Atluri V, Xavier MN, Franchi L, Núñez G, Legrand T, Flavell RA, De Bolle X, Letesson JJ, Tsolis RM. Innate immune recognition of flagellin limits systemic persistence of Brucella. Cellular Microbiology. 15: 942-60. PMID 23227931 DOI: 10.1111/cmi.12088 |
1 |
|
| 2013 |
Han MS, Jung DY, Morel C, Lakhani SA, Kim JK, Flavell RA, Davis RJ. JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation. Science (New York, N.Y.). 339: 218-22. PMID 23223452 DOI: 10.1126/science.1227568 |
1 |
|
| 2013 |
McGee HM, Schmidt BA, Booth CJ, Yancopoulos GD, Valenzuela DM, Murphy AJ, Stevens S, Flavell RA, Horsley V. IL-22 promotes fibroblast-mediated wound repair in the skin. The Journal of Investigative Dermatology. 133: 1321-9. PMID 23223145 DOI: 10.1038/jid.2012.463 |
1 |
|
| 2013 |
Chaiyachati BH, Kaundal RK, Zhao J, Wu J, Flavell R, Chi T. LoxP-FRT Trap (LOFT): a simple and flexible system for conventional and reversible gene targeting. Bmc Biology. 10: 96. PMID 23198860 DOI: 10.1186/1741-7007-10-96 |
1 |
|
| 2012 |
Huber S, Gagliani N, Zenewicz LA, Huber FJ, Bosurgi L, Hu B, Hedl M, Zhang W, O'Connor W, Murphy AJ, Valenzuela DM, Yancopoulos GD, Booth CJ, Cho JH, Ouyang W, ... ... Flavell RA, et al. IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine. Nature. 491: 259-63. PMID 23075849 DOI: 10.1038/nature11535 |
1 |
|
| 2012 |
Joly S, Eisenbarth SC, Olivier AK, Williams A, Kaplan DH, Cassel SL, Flavell RA, Sutterwala FS. Cutting edge: Nlrp10 is essential for protective antifungal adaptive immunity against Candida albicans. Journal of Immunology (Baltimore, Md. : 1950). 189: 4713-7. PMID 23071280 DOI: 10.4049/jimmunol.1201715 |
0.44 |
|
| 2012 |
Hoshi N, Schenten D, Nish SA, Walther Z, Gagliani N, Flavell RA, Reizis B, Shen Z, Fox JG, Iwasaki A, Medzhitov R. MyD88 signalling in colonic mononuclear phagocytes drives colitis in IL-10-deficient mice. Nature Communications. 3: 1120. PMID 23047678 DOI: 10.1038/ncomms2113 |
1 |
|
| 2012 |
Wang P, Bai F, Zenewicz LA, Dai J, Gate D, Cheng G, Yang L, Qian F, Yuan X, Montgomery RR, Flavell RA, Town T, Fikrig E. IL-22 signaling contributes to West Nile encephalitis pathogenesis. Plos One. 7: e44153. PMID 22952908 DOI: 10.1371/journal.pone.0044153 |
1 |
|
| 2011 |
Allen SJ, Mott KR, Wechsler SL, Flavell RA, Town T, Ghiasi H. Adaptive and innate transforming growth factor beta signaling impact herpes simplex virus 1 latency and reactivation. Journal of Virology. 85: 11448-56. PMID 21880769 DOI: 10.1128/JVI.00678-11 |
1 |
|
| 2011 |
Esplugues E, Huber S, Gagliani N, Hauser AE, Town T, Wan YY, O'Connor W, Rongvaux A, Van Rooijen N, Haberman AM, Iwakura Y, Kuchroo VK, Kolls JK, Bluestone JA, Herold KC, ... Flavell RA, et al. Control of TH17 cells occurs in the small intestine. Nature. 475: 514-8. PMID 21765430 DOI: 10.1038/nature10228 |
1 |
|
| 2011 |
Weisser SB, McLarren KW, Voglmaier N, van Netten-Thomas CJ, Antov A, Flavell RA, Sly LM. Alternative activation of macrophages by IL-4 requires SHIP degradation. European Journal of Immunology. 41: 1742-53. PMID 21469115 DOI: 10.1002/eji.201041105 |
0.72 |
|
| 2011 |
Mott KR, Gate D, Zandian M, Allen SJ, Rajasagi NK, van Rooijen N, Chen S, Arditi M, Rouse BT, Flavell RA, Town T, Ghiasi H. Macrophage IL-12p70 signaling prevents HSV-1-induced CNS autoimmunity triggered by autoaggressive CD4+ Tregs. Investigative Ophthalmology & Visual Science. 52: 2321-33. PMID 21220560 DOI: 10.1167/iovs.10-6536 |
1 |
|
| 2009 |
Bai F, Town T, Qian F, Wang P, Kamanaka M, Connolly TM, Gate D, Montgomery RR, Flavell RA, Fikrig E. IL-10 signaling blockade controls murine West Nile virus infection. Plos Pathogens. 5: e1000610. PMID 19816558 DOI: 10.1371/journal.ppat.1000610 |
1 |
|
| 2009 |
Kuroda E, Ho V, Ruschmann J, Antignano F, Hamilton M, Rauh MJ, Antov A, Flavell RA, Sly LM, Krystal G. SHIP represses the generation of IL-3-induced M2 macrophages by inhibiting IL-4 production from basophils. Journal of Immunology (Baltimore, Md. : 1950). 183: 3652-60. PMID 19710468 DOI: 10.4049/jimmunol.0900864 |
0.72 |
|
| 2009 |
Matza D, Badou A, Jha MK, Willinger T, Antov A, Sanjabi S, Kobayashi KS, Marchesi VT, Flavell RA. Requirement for AHNAK1-mediated calcium signaling during T lymphocyte cytolysis. Proceedings of the National Academy of Sciences of the United States of America. 106: 9785-90. PMID 19497879 DOI: 10.1073/pnas.0902844106 |
0.72 |
|
| 2009 |
O'Connor W, Kamanaka M, Booth CJ, Town T, Nakae S, Iwakura Y, Kolls JK, Flavell RA. A protective function for interleukin 17A in T cell-mediated intestinal inflammation. Nature Immunology. 10: 603-9. PMID 19448631 DOI: 10.1038/ni.1736 |
1 |
|
| 2009 |
Zenewicz LA, Antov A, Flavell RA. CD4 T-cell differentiation and inflammatory bowel disease. Trends in Molecular Medicine. 15: 199-207. PMID 19362058 DOI: 10.1016/j.molmed.2009.03.002 |
0.72 |
|
| 2009 |
Town T, Bai F, Wang T, Kaplan AT, Qian F, Montgomery RR, Anderson JF, Flavell RA, Fikrig E. Toll-like receptor 7 mitigates lethal West Nile encephalitis via interleukin 23-dependent immune cell infiltration and homing. Immunity. 30: 242-53. PMID 19200759 DOI: 10.1016/j.immuni.2008.11.012 |
1 |
|
| 2009 |
Amsen D, Antov A, Flavell RA. The different faces of Notch in T-helper-cell differentiation. Nature Reviews. Immunology. 9: 116-24. PMID 19165228 DOI: 10.1038/nri2488 |
0.72 |
|
| 2008 |
Breunig JJ, Sarkisian MR, Arellano JI, Morozov YM, Ayoub AE, Sojitra S, Wang B, Flavell RA, Rakic P, Town T. Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling. Proceedings of the National Academy of Sciences of the United States of America. 105: 13127-32. PMID 18728187 DOI: 10.1073/pnas.0804558105 |
1 |
|
| 2008 |
Laouar Y, Town T, Jeng D, Tran E, Wan Y, Kuchroo VK, Flavell RA. TGF-beta signaling in dendritic cells is a prerequisite for the control of autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 105: 10865-70. PMID 18669656 DOI: 10.1073/pnas.0805058105 |
1 |
|
| 2008 |
Wang S, Welte T, McGargill M, Town T, Thompson J, Anderson JF, Flavell RA, Fikrig E, Hedrick SM, Wang T. Drak2 contributes to West Nile virus entry into the brain and lethal encephalitis. Journal of Immunology (Baltimore, Md. : 1950). 181: 2084-91. PMID 18641347 |
1 |
|
| 2008 |
Town T, Laouar Y, Pittenger C, Mori T, Szekely CA, Tan J, Duman RS, Flavell RA. Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology. Nature Medicine. 14: 681-7. PMID 18516051 DOI: 10.1038/nm1781 |
1 |
|
| 2008 |
Mohanty S, Town T, Yagi T, Scheidig C, Kwan KY, Allore HG, Flavell RA, Shaw AC. Defective p53 engagement after the induction of DNA damage in cells deficient in topoisomerase 3beta. Proceedings of the National Academy of Sciences of the United States of America. 105: 5063-8. PMID 18367668 DOI: 10.1073/pnas.0801235105 |
1 |
|
| 2008 |
Town T, Breunig JJ, Sarkisian MR, Spilianakis C, Ayoub AE, Liu X, Ferrandino AF, Gallagher AR, Li MO, Rakic P, Flavell RA. The stumpy gene is required for mammalian ciliogenesis. Proceedings of the National Academy of Sciences of the United States of America. 105: 2853-8. PMID 18287022 DOI: 10.1073/pnas.0712385105 |
1 |
|
| 2007 |
Deane JA, Pisitkun P, Barrett RS, Feigenbaum L, Town T, Ward JM, Flavell RA, Bolland S. Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation. Immunity. 27: 801-10. PMID 17997333 DOI: 10.1016/j.immuni.2007.09.009 |
1 |
|
| 2007 |
Kim ST, Fields PE, Flavell RA. Demethylation of a specific hypersensitive site in the Th2 locus control region. Proceedings of the National Academy of Sciences of the United States of America. 104: 17052-7. PMID 17940027 DOI: 10.1073/pnas.0708293104 |
0.68 |
|
| 2007 |
Watanabe A, Hashmi A, Gomes DA, Town T, Badou A, Flavell RA, Mehal WZ. Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9. Hepatology (Baltimore, Md.). 46: 1509-18. PMID 17705260 DOI: 10.1002/hep.21867 |
0.64 |
|
| 2007 |
Amsen D, Antov A, Jankovic D, Sher A, Radtke F, Souabni A, Busslinger M, McCright B, Gridley T, Flavell RA. Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. Immunity. 27: 89-99. PMID 17658279 DOI: 10.1016/j.immuni.2007.05.021 |
0.72 |
|
| 2007 |
Chen L, He W, Kim ST, Tao J, Gao Y, Chi H, Intlekofer AM, Harvey B, Reiner SL, Yin Z, Flavell RA, Craft J. Epigenetic and transcriptional programs lead to default IFN-gamma production by gammadelta T cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 2730-6. PMID 17312115 |
1 |
|
| 2007 |
Bai F, Town T, Pradhan D, Cox J, Ashish, Ledizet M, Anderson JF, Flavell RA, Krueger JK, Koski RA, Fikrig E. Antiviral peptides targeting the west nile virus envelope protein. Journal of Virology. 81: 2047-55. PMID 17151121 DOI: 10.1128/JVI.01840-06 |
1 |
|
| 2006 |
Kamanaka M, Kim ST, Wan YY, Sutterwala FS, Lara-Tejero M, Galán JE, Harhaj E, Flavell RA. Expression of interleukin-10 in intestinal lymphocytes detected by an interleukin-10 reporter knockin tiger mouse. Immunity. 25: 941-52. PMID 17137799 DOI: 10.1016/j.immuni.2006.09.013 |
0.68 |
|
| 2006 |
Wang R, Town T, Gokarn V, Flavell RA, Chandawarkar RY. HSP70 enhances macrophage phagocytosis by interaction with lipid raft-associated TLR-7 and upregulating p38 MAPK and PI3K pathways. The Journal of Surgical Research. 136: 58-69. PMID 16979664 DOI: 10.1016/j.jss.2006.06.003 |
0.64 |
|
| 2006 |
Lee GR, Kim ST, Spilianakis CG, Fields PE, Flavell RA. T helper cell differentiation: regulation by cis elements and epigenetics. Immunity. 24: 369-79. PMID 16618596 DOI: 10.1016/j.immuni.2006.03.007 |
0.76 |
|
| 2006 |
Town T, Jeng D, Alexopoulou L, Tan J, Flavell RA. Microglia recognize double-stranded RNA via TLR3. Journal of Immunology (Baltimore, Md. : 1950). 176: 3804-12. PMID 16517751 |
0.64 |
|
| 2005 |
Town T, Tan J, Flavell RA, Mullan M. T-cells in Alzheimer's disease. Neuromolecular Medicine. 7: 255-64. PMID 16247185 DOI: 10.1385/NMM:7:3:255 |
1 |
|
| 2005 |
Kimberly WT, Zheng JB, Town T, Flavell RA, Selkoe DJ. Physiological regulation of the beta-amyloid precursor protein signaling domain by c-Jun N-terminal kinase JNK3 during neuronal differentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5533-43. PMID 15944381 DOI: 10.1523/JNEUROSCI.4883-04.2005 |
1 |
|
| 2005 |
Spilianakis CG, Lalioti MD, Town T, Lee GR, Flavell RA. Interchromosomal associations between alternatively expressed loci. Nature. 435: 637-45. PMID 15880101 DOI: 10.1038/nature03574 |
0.76 |
|
| 2005 |
Townsend KP, Town T, Mori T, Lue LF, Shytle D, Sanberg PR, Morgan D, Fernandez F, Flavell RA, Tan J. CD40 signaling regulates innate and adaptive activation of microglia in response to amyloid beta-peptide. European Journal of Immunology. 35: 901-10. PMID 15688347 DOI: 10.1002/eji.200425585 |
1 |
|
| 2004 |
Fields PE, Lee GR, Kim ST, Bartsevich VV, Flavell RA. Th2-specific chromatin remodeling and enhancer activity in the Th2 cytokine locus control region. Immunity. 21: 865-76. PMID 15589174 DOI: 10.1016/j.immuni.2004.10.015 |
0.76 |
|
| 2004 |
Wang T, Town T, Alexopoulou L, Anderson JF, Fikrig E, Flavell RA. Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis. Nature Medicine. 10: 1366-73. PMID 15558055 DOI: 10.1038/nm1140 |
1 |
|
| 2003 |
Blander JM, Sant'Angelo DB, Metz D, Kim SW, Flavell RA, Bottomly K, Janeway CA. A pool of central memory-like CD4 T cells contains effector memory precursors. Journal of Immunology (Baltimore, Md. : 1950). 170: 2940-8. PMID 12626545 |
1 |
|
| 2002 |
Tan J, Town T, Crawford F, Mori T, DelleDonne A, Crescentini R, Obregon D, Flavell RA, Mullan MJ. Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice. Nature Neuroscience. 5: 1288-93. PMID 12402041 DOI: 10.1038/nn968 |
0.64 |
|
| 2002 |
Fields PE, Kim ST, Flavell RA. Cutting edge: changes in histone acetylation at the IL-4 and IFN-gamma loci accompany Th1/Th2 differentiation. Journal of Immunology (Baltimore, Md. : 1950). 169: 647-50. PMID 12097365 |
0.68 |
|
| 2002 |
Tan J, Town T, Mori T, Obregon D, Wu Y, DelleDonne A, Rojiani A, Crawford F, Flavell RA, Mullan M. CD40 is expressed and functional on neuronal cells. The Embo Journal. 21: 643-52. PMID 11847112 DOI: 10.1093/emboj/21.4.643 |
1 |
|
| 1999 |
Tan J, Town T, Paris D, Mori T, Suo Z, Crawford F, Mattson MP, Flavell RA, Mullan M. Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation. Science (New York, N.Y.). 286: 2352-5. PMID 10600748 DOI: 10.1126/science.286.5448.2352 |
1 |
|
| 1978 |
van den Berg J, van Ooyen A, Mantei N, Schamböck A, Grosveld G, Flavell RA, Weissmann C. Comparison of cloned rabbit and mouse beta-globin genes showing strong evolutionary divergence of two homologous pairs of introns. Nature. 276: 37-44. PMID 264241 DOI: 10.1038/276037a0 |
1 |
|
| 1977 |
Sabo DL, Domingo E, Bandle EF, Flavell RA, Weissmann C. A guanosine to adenosine transition in the 3' terminal extracistronic region of bacteriophage Q beta RNA leading to loss of infectivity. Journal of Molecular Biology. 112: 235-52. PMID 875018 DOI: 10.1016/S0022-2836(77)80141-1 |
1 |
|
| 1976 |
Domingo E, Flavell RA, Weissmann C. In vitro site-directed mutagenesis: generation and properties of an infectious extracistronic mutant of bacteriophage Qbeta. Gene. 1: 3-25. PMID 1052322 |
1 |
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| 1976 |
Mol JN, Flavell RA, Borst P. The presence of (dA.dT)20-25 tracts in the DNA of primitive eukaryotes. Nucleic Acids Research. 3: 2367-77. PMID 823532 DOI: 10.1093/nar/3.9.2367 |
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| 1975 |
Flavell RA, Sabo DL, Bandle EF, Weissmann C. Site-directed mutagenesis: effect of an extracistronic mutation on the in vitro propagation of bacteriophage Qbeta RNA. Proceedings of the National Academy of Sciences of the United States of America. 72: 367-71. PMID 47176 |
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| 1974 |
Flavell RA, Birfelder EJ, Sanders JP, Borst P. DNA-DNA hybridization on nitrocellulose filters. 1. General considerations and non-ideal kinetics. European Journal of Biochemistry. 47: 535-43. PMID 4611768 DOI: 10.1111/j.1432-1033.1974.tb03722.x |
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| 1974 |
Flavell RA, Sabo DL, Bandle EF, Weissmann C. Site-directed mutagenesis: generation of an extracistronic mutation in bacteriophage Q beta RNA. Journal of Molecular Biology. 89: 255-72. PMID 4444051 DOI: 10.1016/0022-2836(74)90517-8 |
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| 1974 |
Flavell RA, Borst P, Birfelder EJ. DNA-DNA hybridization on nitrocellulose filters. 2. Concatenation effects. European Journal of Biochemistry. 47: 545-8. PMID 4434995 DOI: 10.1111/j.1432-1033.1974.tb03723.x |
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| 1973 |
Arnberg AC, Van Bruggen EFJ, Flavell RA, Borst P. DNA synthesis by isolated mitochondria V. Electron microscopy of replicative intermediates Bba Section Nucleic Acids and Protein Synthesis. 308: 276-284. PMID 4706002 DOI: 10.1016/0005-2787(73)90157-3 |
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| 1973 |
Sanders JP, Flavell RA, Borst P, Mol JN. Nature of the base sequence conserved in the mitochondrial DNA of a low-density petite. Biochimica Et Biophysica Acta. 312: 441-57. PMID 4579629 DOI: 10.1016/0005-2787(73)90443-7 |
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| 1972 |
Flavell RA, Borst P, ter Schegget J. DNA synthesis by isolated mitochondria. IV. Isolation of an intermediate containing newly synthesized DNA in full-length light strands. Biochimica Et Biophysica Acta. 272: 341-9. PMID 5049468 |
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| 1972 |
Arnberg AC, Van Bruggen EFJ, Schutgens RBH, Flavell RA, Borst P. Multiple D-loops in Tetrahymena mitochondrial DNA Bba Section Nucleic Acids and Protein Synthesis. 272: 487-493. PMID 4626236 DOI: 10.1016/0005-2787(72)90503-5 |
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| 1972 |
van Kreijl CF, Borst P, Flavell RA, Hollenberg CP. Pyrimidine tract analysis of mtDNA from a "low-density" petite mutant of yeast. Biochimica Et Biophysica Acta. 277: 61-70. PMID 4559803 DOI: 10.1016/0005-2787(72)90352-8 |
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| 1972 |
Hollenberg CP, Borst P, Flavell RA, Van Kreijl CF, Van Bruggen EFJ, Arnberg AC. The unusual properties of mtDNA from a "low-density" petite mutant of yeast Bba Section Nucleic Acids and Protein Synthesis. 277: 44-58. PMID 4559801 DOI: 10.1016/0005-2787(72)90350-4 |
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| 1971 |
Flavell RA, Jones IG. Base sequence distribution in Tetrahymena mitochondrial DNA. Febs Letters. 14: 354-356. PMID 11945796 DOI: 10.1016/0014-5793(71)80299-5 |
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| 1971 |
ter Schegget J, Flavell RA, Borst P. DNA synthesis by isolated mitochondria. 3. Characterization of D-loop DNA, a novel intermediate in mtDNA synthesis. Biochimica Et Biophysica Acta. 254: 1-14. PMID 4943979 |
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