Marco Bortolato, MD, PhD - Publications

Affiliations: 
Pharmacology and Toxicology University of Kansas, Lawrence, KS, United States 
Area:
Behavioral Neuroscience, dopamine, neurosteroids, aggression, Tourette syndrome, schizophrenia, autism

80 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Floris G, Scheggi S, Pes R, Bortolato M. The steroidogenic inhibitor finasteride reverses pramipexole-induced alterations in probability discounting. Brain Research Bulletin. 181: 157-166. PMID 35122898 DOI: 10.1016/j.brainresbull.2022.01.020  0.301
2020 Kolla NJ, Bortolato M. The role of monoamine oxidase A in the neurobiology of aggressive, antisocial, and violent behavior: a tale of mice and men. Progress in Neurobiology. 101875. PMID 32574581 DOI: 10.1016/J.Pneurobio.2020.101875  0.345
2020 Orrù M, Strathman HJ, Floris G, Scheggi S, Levant B, Bortolato M. The adverse effects of pramipexole on probability discounting are not reversed by acute D or D receptor antagonism. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 31983530 DOI: 10.1016/J.Euroneuro.2020.01.005  0.374
2019 Frau R, Traccis F, Bortolato M. Neurobehavioral complications of sleep deprivation: shedding light on the emerging role of neuroactive steroids. Journal of Neuroendocrinology. e12792. PMID 31505075 DOI: 10.1111/Jne.12792  0.305
2019 Mosher LJ, Cadeddu R, Yen S, Staudinger JL, Traccis F, Fowler SC, Maguire JL, Bortolato M. Allopregnanolone is required for prepulse inhibition deficits induced by D dopamine receptor activation. Psychoneuroendocrinology. 108: 53-61. PMID 31228750 DOI: 10.1016/J.Psyneuen.2019.06.009  0.386
2019 Cadeddu R, Bäckström T, Floris G, Nordkild P, Segerdahl M, Bortolato M. Isoallopregnanolone reduces tic-like behaviors in the D1CT-7 mouse model of Tourette syndrome. Journal of Neuroendocrinology. e12754. PMID 31175669 DOI: 10.1111/Jne.12754  0.371
2019 Frau R, Fanni S, Serra V, Simola N, Godar S, Traccis F, Devoto P, Bortolato M, Melis M. Dysfunctional mesocortical dopamine circuit at pre-adolescence is associated to aggressive behavior in MAO-A hypomorphic mice exposed to early life stress. Neuropharmacology. PMID 30738037 DOI: 10.1016/J.Neuropharm.2019.01.032  0.403
2019 Godar SC, Mosher LJ, Scheggi S, Devoto P, Moench KM, Strathman HJ, Jones CM, Frau R, Melis M, Gambarana C, Wilkinson B, DeMontis MG, Fowler SC, Coba MP, Wellman CL, ... ... Bortolato M, et al. Gene-environment interactions in antisocial behavior are mediated by early-life 5-HT receptor activation. Neuropharmacology. PMID 30716416 DOI: 10.1016/J.Neuropharm.2019.01.028  0.359
2018 Fanni S, Scheggi S, Rossi F, Tronci E, Traccis F, Stancampiano R, De Montis MG, Devoto P, Gambarana C, Bortolato M, Frau R, Carta M. 5alpha-reductase inhibitors dampen L-DOPA-induced dyskinesia via normalization of dopamine D1-receptor signaling pathway and D1-D3 receptor interaction. Neurobiology of Disease. 121: 120-130. PMID 30261284 DOI: 10.1016/J.Nbd.2018.09.018  0.371
2018 Frau R, Bortolato M. Repurposing steroidogenesis inhibitors for the therapy of neuropsychiatric disorders: Promises and caveats. Neuropharmacology. PMID 29907425 DOI: 10.1016/J.Neuropharm.2018.05.013  0.342
2018 Bortolato M, Floris G, Shih JC. From aggression to autism: new perspectives on the behavioral sequelae of monoamine oxidase deficiency. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 29748850 DOI: 10.1007/S00702-018-1888-Y  0.379
2018 Mosher LJ, Godar SC, Morissette M, McFarlin KM, Scheggi S, Gambarana C, Fowler SC, Di Paolo T, Bortolato M. Steroid 5α-reductase 2 deficiency leads to reduced dominance-related and impulse-control behaviors. Psychoneuroendocrinology. 91: 95-104. PMID 29544191 DOI: 10.1016/J.Psyneuen.2018.02.007  0.392
2018 Santangelo A, Bortolato M, Mosher LJ, Crescimanno G, Di Giovanni G, Cassioli E, Ricca V, Casarrubea M. Behavioral fragmentation in the D1CT-7 mouse model of Tourette's syndrome. Cns Neuroscience & Therapeutics. PMID 29314714 DOI: 10.1111/Cns.12789  0.308
2017 Mosher LJ, Godar SC, Nelson M, Fowler SC, Pinna G, Bortolato M. Allopregnanolone mediates the exacerbation of Tourette-like responses by acute stress in mouse models. Scientific Reports. 7: 3348. PMID 28611376 DOI: 10.1038/S41598-017-03649-1  0.368
2017 Bortolato M, Pittenger C. Modeling tics in rodents: Conceptual challenges and paths forward. Journal of Neuroscience Methods. PMID 28237575 DOI: 10.1016/J.Jneumeth.2017.02.007  0.305
2017 Frau R, Savoia P, Fanni S, Fiorentini C, Fidalgo C, Tronci E, Stancampiano R, Meloni M, Cannas A, Marrosu F, Bortolato M, Devoto P, Missale C, Carta M. The 5-alpha reductase inhibitor finasteride reduces dyskinesia in a rat model of Parkinson's disease. Experimental Neurology. PMID 28131725 DOI: 10.1016/J.Expneurol.2017.01.012  0.374
2017 Frau R, Bini V, Soggiu A, Scheggi S, Pardu A, Fanni S, Roncada P, Puligheddu M, Marrosu F, Caruso D, Devoto P, Bortolato M. The Neurosteroidogenic Enzyme 5α-Reductase Mediates Psychotic-Like Complications of Sleep Deprivation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28102229 DOI: 10.1038/Npp.2017.13  0.375
2017 Fowler SC, Mosher LJ, Godar SC, Bortolato M. Assessment of gait and sensorimotor deficits in the D1CT-7 mouse model of Tourette syndrome. Journal of Neuroscience Methods. PMID 28099872 DOI: 10.1016/J.Jneumeth.2017.01.009  0.317
2016 Godar SC, Bortolato M. What makes you tic? Translational approaches to study the role of stress and contextual triggers in Tourette syndrome. Neuroscience and Biobehavioral Reviews. PMID 27939782 DOI: 10.1016/J.Neubiorev.2016.10.003  0.319
2016 Pes R, Godar SC, Fox AT, Burgeno LM, Strathman HJ, Jarmolowicz DP, Devoto P, Levant B, Phillips PE, Fowler SC, Bortolato M. Pramipexole enhances disadvantageous decision-making: Lack of relation to changes in phasic dopamine release. Neuropharmacology. PMID 27889491 DOI: 10.1016/J.Neuropharm.2016.11.014  0.703
2016 Soggiu A, Piras C, Greco V, Devoto P, Urbani A, Calzetta L, Bortolato M, Roncada P. Exploring the neural mechanisms of finasteride: a proteomic analysis in the nucleus accumbens. Psychoneuroendocrinology. 74: 387-396. PMID 27750143 DOI: 10.1016/J.Psyneuen.2016.10.001  0.408
2016 Godar SC, Fite PJ, McFarlin KM, Bortolato M. The role of monoamine oxidase a in aggression: Current translational developments and future challenges. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 26776902 DOI: 10.1016/J.Pnpbp.2016.01.001  0.36
2016 Frau R, Mosher LJ, Bini V, Pillolla G, Pes R, Saba P, Fanni S, Devoto P, Bortolato M. The neurosteroidogenic enzyme 5α-reductase modulates the role of D1 dopamine receptors in rat sensorimotor gating. Psychoneuroendocrinology. 63: 59-67. PMID 26415119 DOI: 10.1016/J.Psyneuen.2015.09.014  0.382
2015 Godar SC, Mosher LJ, Strathman HJ, Gochi AM, Jones CM, Fowler SC, Bortolato M. The D1CT-7 mouse model of Tourette syndrome displays sensorimotor gating deficits in response to spatial confinement. British Journal of Pharmacology. PMID 26171666 DOI: 10.1111/Bph.13243  0.313
2015 Mosher LJ, Frau R, Pardu A, Pes R, Devoto P, Bortolato M. Selective activation of D1 dopamine receptors impairs sensorimotor gating in Long-Evans rats. British Journal of Pharmacology. PMID 26101934 DOI: 10.1111/Bph.13232  0.387
2015 Frau R, Abbiati F, Bini V, Casti A, Caruso D, Devoto P, Bortolato M. Targeting neurosteroid synthesis as a therapy for schizophrenia-related alterations induced by early psychosocial stress. Schizophrenia Research. 168: 640-8. PMID 25999042 DOI: 10.1016/J.Schres.2015.04.044  0.348
2015 Godar SC, Bortolato M, Richards SE, Li FG, Chen K, Wellman CL, Shih JC. Monoamine Oxidase A is Required for Rapid Dendritic Remodeling in Response to Stress. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25857821 DOI: 10.1093/Ijnp/Pyv035  0.329
2014 Godar SC, Mosher LJ, Di Giovanni G, Bortolato M. Animal models of tic disorders: a translational perspective. Journal of Neuroscience Methods. 238: 54-69. PMID 25244952 DOI: 10.1016/J.Jneumeth.2014.09.008  0.314
2014 Godar SC, Bortolato M, Castelli MP, Casti A, Casu A, Chen K, Ennas MG, Tambaro S, Shih JC. The aggression and behavioral abnormalities associated with monoamine oxidase A deficiency are rescued by acute inhibition of serotonin reuptake. Journal of Psychiatric Research. 56: 1-9. PMID 24882701 DOI: 10.1016/J.Jpsychires.2014.04.014  0.368
2014 Moskovitz J, Walss-Bass C, Cruz DA, Thompson PM, Bortolato M. Methionine sulfoxide reductase regulates brain catechol-O-methyl transferase activity. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 17: 1707-13. PMID 24735585 DOI: 10.1017/S1461145714000467  0.336
2014 Frau R, Bini V, Pillolla G, Malherbe P, Pardu A, Thomas AW, Devoto P, Bortolato M. Positive allosteric modulation of GABAB receptors ameliorates sensorimotor gating in rodent models. Cns Neuroscience & Therapeutics. 20: 679-84. PMID 24703381 DOI: 10.1111/Cns.12261  0.347
2014 Godar SC, Bortolato M. Gene-sex interactions in schizophrenia: focus on dopamine neurotransmission. Frontiers in Behavioral Neuroscience. 8: 71. PMID 24639636 DOI: 10.3389/Fnbeh.2014.00071  0.303
2014 Bortolato M, Bini V, Frau R, Devoto P, Pardu A, Fan Y, Solbrig MV. Juvenile cannabinoid treatment induces frontostriatal gliogenesis in Lewis rats. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 24: 974-85. PMID 24630433 DOI: 10.1016/J.Euroneuro.2013.12.011  0.39
2014 Frau R, Bini V, Pes R, Pillolla G, Saba P, Devoto P, Bortolato M. Inhibition of 17α-hydroxylase/C17,20 lyase reduces gating deficits consequent to dopaminergic activation. Psychoneuroendocrinology. 39: 204-13. PMID 24140269 DOI: 10.1016/J.Psyneuen.2013.09.014  0.385
2013 Bortolato M, Godar SC, Tambaro S, Li FG, Devoto P, Coba MP, Chen K, Shih JC. Early postnatal inhibition of serotonin synthesis results in long-term reductions of perseverative behaviors, but not aggression, in MAO A-deficient mice. Neuropharmacology. 75: 223-32. PMID 23871843 DOI: 10.1016/J.Neuropharm.2013.07.003  0.351
2013 Singh C, Bortolato M, Bali N, Godar SC, Scott AL, Chen K, Thompson RF, Shih JC. Cognitive abnormalities and hippocampal alterations in monoamine oxidase A and B knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 110: 12816-21. PMID 23858446 DOI: 10.1073/Pnas.1308037110  0.348
2013 Bortolato M, Frau R, Godar SC, Mosher LJ, Paba S, Marrosu F, Devoto P. The implication of neuroactive steroids in Tourette's syndrome pathogenesis: A role for 5α-reductase? Journal of Neuroendocrinology. 25: 1196-208. PMID 23795653 DOI: 10.1111/Jne.12066  0.341
2013 Wyatt LR, Godar SC, Khoja S, Jakowec MW, Alkana RL, Bortolato M, Davies DL. Sociocommunicative and sensorimotor impairments in male P2X4-deficient mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 1993-2002. PMID 23604007 DOI: 10.1038/Npp.2013.98  0.371
2013 Tambaro S, Tomasi ML, Bortolato M. Long-term CB₁ receptor blockade enhances vulnerability to anxiogenic-like effects of cannabinoids. Neuropharmacology. 70: 268-77. PMID 23462228 DOI: 10.1016/J.Neuropharm.2013.02.009  0.391
2013 Bortolato M, Yardley MM, Khoja S, Godar SC, Asatryan L, Finn DA, Alkana RL, Louie SG, Davies DL. Pharmacological insights into the role of P2X4 receptors in behavioural regulation: lessons from ivermectin. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 1059-70. PMID 23174033 DOI: 10.1017/S1461145712000909  0.378
2013 Frau R, Pillolla G, Bini V, Tambaro S, Devoto P, Bortolato M. Inhibition of 5α-reductase attenuates behavioral effects of D1-, but not D2-like receptor agonists in C57BL/6 mice. Psychoneuroendocrinology. 38: 542-51. PMID 22877998 DOI: 10.1016/J.Psyneuen.2012.07.014  0.423
2013 Bortolato M, Godar SC, Alzghoul L, Zhang J, Darling RD, Simpson KL, Bini V, Chen K, Wellman CL, Lin RC, Shih JC. Monoamine oxidase A and A/B knockout mice display autistic-like features. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 869-88. PMID 22850464 DOI: 10.1017/S1461145712000715  0.343
2012 Alzghoul L, Bortolato M, Delis F, Thanos PK, Darling RD, Godar SC, Zhang J, Grant S, Wang GJ, Simpson KL, Chen K, Volkow ND, Lin RC, Shih JC. Altered cerebellar organization and function in monoamine oxidase A hypomorphic mice. Neuropharmacology. 63: 1208-17. PMID 22971542 DOI: 10.1016/J.Neuropharm.2012.08.003  0.346
2012 Bortolato M, Godar SC, Melis M, Soggiu A, Roncada P, Casu A, Flore G, Chen K, Frau R, Urbani A, Castelli MP, Devoto P, Shih JC. NMDARs mediate the role of monoamine oxidase A in pathological aggression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8574-82. PMID 22723698 DOI: 10.1523/Jneurosci.0225-12.2012  0.385
2012 Tambaro S, Bortolato M. Cannabinoid-related agents in the treatment of anxiety disorders: current knowledge and future perspectives. Recent Patents On Cns Drug Discovery. 7: 25-40. PMID 22280339 DOI: 10.2174/157488912798842269  0.33
2012 Devoto P, Frau R, Bini V, Pillolla G, Saba P, Flore G, Corona M, Marrosu F, Bortolato M. Inhibition of 5α-reductase in the nucleus accumbens counters sensorimotor gating deficits induced by dopaminergic activation. Psychoneuroendocrinology. 37: 1630-45. PMID 22029952 DOI: 10.1016/J.Psyneuen.2011.09.018  0.428
2011 Bortolato M, Shih JC. Behavioral outcomes of monoamine oxidase deficiency: preclinical and clinical evidence. International Review of Neurobiology. 100: 13-42. PMID 21971001 DOI: 10.1016/B978-0-12-386467-3.00002-9  0.349
2011 Bortolato M, Chen K, Godar SC, Chen G, Wu W, Rebrin I, Farrell MR, Scott AL, Wellman CL, Shih JC. Social deficits and perseverative behaviors, but not overt aggression, in MAO-A hypomorphic mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 2674-88. PMID 21832987 DOI: 10.1038/Npp.2011.157  0.334
2011 Paba S, Frau R, Godar SC, Devoto P, Marrosu F, Bortolato M. Steroid 5α-reductase as a novel therapeutic target for schizophrenia and other neuropsychiatric disorders. Current Pharmaceutical Design. 17: 151-67. PMID 21361868 DOI: 10.2174/138161211795049589  0.31
2011 Bortolato M, Devoto P, Roncada P, Frau R, Flore G, Saba P, Pistritto G, Soggiu A, Pisanu S, Zappala A, Ristaldi MS, Tattoli M, Cuomo V, Marrosu F, Barbaccia ML. Isolation rearing-induced reduction of brain 5α-reductase expression: relevance to dopaminergic impairments. Neuropharmacology. 60: 1301-8. PMID 21256141 DOI: 10.1016/J.Neuropharm.2011.01.013  0.362
2011 Godar SC, Bortolato M, Frau R, Dousti M, Chen K, Shih JC. Maladaptive defensive behaviours in monoamine oxidase A-deficient mice. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 1195-207. PMID 21156093 DOI: 10.1017/S1461145710001483  0.333
2010 Bortolato M, Bini V, Tambaro S. Vulnerability Factors for the Psychiatric and Behavioral Effects of Cannabis. Pharmaceuticals (Basel, Switzerland). 3: 2799-2820. PMID 27713377 DOI: 10.3390/Ph3092799  0.317
2010 Bortolato M, Godar SC. Animal models of virus-induced neurobehavioral sequelae: recent advances, methodological issues, and future prospects. Interdisciplinary Perspectives On Infectious Diseases. 2010: 380456. PMID 20490350 DOI: 10.1155/2010/380456  0.311
2010 Sciolino NR, Bortolato M, Eisenstein SA, Fu J, Oveisi F, Hohmann AG, Piomelli D. Social isolation and chronic handling alter endocannabinoid signaling and behavioral reactivity to context in adult rats. Neuroscience. 168: 371-86. PMID 20394803 DOI: 10.1016/J.Neuroscience.2010.04.007  0.33
2010 Bortolato M, Frau R, Bini V, Luesu W, Loriga R, Collu M, Gessa GL, Ennas MG, Castelli MP. Methamphetamine neurotoxicity increases brain expression and alters behavioral functions of CB₁ cannabinoid receptors. Journal of Psychiatric Research. 44: 944-55. PMID 20378129 DOI: 10.1016/J.Jpsychires.2010.03.002  0.394
2010 Bortolato M, Frau R, Orrù M, Fà M, Dessì C, Puligheddu M, Barberini L, Pillolla G, Polizzi L, Santoni F, Mereu G, Marrosu F. GABAB receptor activation exacerbates spontaneous spike-and-wave discharges in DBA/2J mice. Seizure. 19: 226-31. PMID 20233662 DOI: 10.1016/J.Seizure.2010.02.007  0.326
2010 Bortolato M, Chen K, Shih JC. The Degradation of Serotonin: Role of MAO Handbook of Behavioral Neuroscience. 21: 203-218. DOI: 10.1016/S1569-7339(10)70079-5  0.304
2009 Bortolato M, Godar SC, Davarian S, Chen K, Shih JC. Behavioral disinhibition and reduced anxiety-like behaviors in monoamine oxidase B-deficient mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2746-57. PMID 19710633 DOI: 10.1038/Npp.2009.118  0.347
2009 Bortolato M, Frau R, Piras AP, Luesu W, Bini V, Diaz G, Gessa G, Ennas MG, Castelli MP. Methamphetamine induces long-term alterations in reactivity to environmental stimuli: correlation with dopaminergic and serotonergic toxicity. Neurotoxicity Research. 15: 232-45. PMID 19384596 DOI: 10.1007/S12640-009-9024-2  0.375
2009 Roncada P, Bortolato M, Frau R, Saba P, Flore G, Soggiu A, Pisanu S, Amoresano A, Carpentieri A, Devoto P. Gating deficits in isolation-reared rats are correlated with alterations in protein expression in nucleus accumbens. Journal of Neurochemistry. 108: 611-20. PMID 19054277 DOI: 10.1111/J.1471-4159.2008.05806.X  0.313
2008 Justinova Z, Mangieri RA, Bortolato M, Chefer SI, Mukhin AG, Clapper JR, King AR, Redhi GH, Yasar S, Piomelli D, Goldberg SR. Fatty acid amide hydrolase inhibition heightens anandamide signaling without producing reinforcing effects in primates. Biological Psychiatry. 64: 930-7. PMID 18814866 DOI: 10.1016/J.Biopsych.2008.08.008  0.324
2008 Bortolato M, Chen K, Shih JC. Monoamine oxidase inactivation: from pathophysiology to therapeutics. Advanced Drug Delivery Reviews. 60: 1527-33. PMID 18652859 DOI: 10.1016/J.Addr.2008.06.002  0.372
2008 Frau R, Orrù M, Puligheddu M, Gessa GL, Mereu G, Marrosu F, Bortolato M. Sleep deprivation disrupts prepulse inhibition of the startle reflex: reversal by antipsychotic drugs. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 11: 947-55. PMID 18477413 DOI: 10.1017/S1461145708008900  0.345
2008 Scott AL, Bortolato M, Chen K, Shih JC. Novel monoamine oxidase A knock out mice with human-like spontaneous mutation. Neuroreport. 19: 739-43. PMID 18418249 DOI: 10.1097/Wnr.0B013E3282Fd6E88  0.304
2008 Bortolato M, Frau R, Orrù M, Bourov Y, Marrosu F, Mereu G, Devoto P, Gessa GL. Antipsychotic-like properties of 5-alpha-reductase inhibitors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 3146-56. PMID 18354385 DOI: 10.1038/Npp.2008.39  0.347
2008 Bortolato M, Frau R, Orrù M, Collu M, Mereu G, Carta M, Fadda F, Stancampiano R. Effects of tryptophan deficiency on prepulse inhibition of the acoustic startle in rats. Psychopharmacology. 198: 191-200. PMID 18330544 DOI: 10.1007/S00213-008-1116-9  0.404
2008 Bortolato M, Piomelli D. Chapter 4.5 The endocannabinoid system and anxiety responses Handbook of Behavioral Neuroscience. 17: 303-324. DOI: 10.1016/S1569-7339(07)00014-8  0.346
2007 Bortolato M, Frau R, Orrù M, Piras AP, Fà M, Tuveri A, Puligheddu M, Gessa GL, Castelli MP, Mereu G, Marrosu F. Activation of GABA(B) receptors reverses spontaneous gating deficits in juvenile DBA/2J mice. Psychopharmacology. 194: 361-9. PMID 17604981 DOI: 10.1007/S00213-007-0845-5  0.341
2007 Bortolato M, Mangieri RA, Fu J, Kim JH, Arguello O, Duranti A, Tontini A, Mor M, Tarzia G, Piomelli D. Antidepressant-like activity of the fatty acid amide hydrolase inhibitor URB597 in a rat model of chronic mild stress. Biological Psychiatry. 62: 1103-10. PMID 17511970 DOI: 10.1016/J.Biopsych.2006.12.001  0.353
2007 Ballmaier M, Bortolato M, Rizzetti C, Zoli M, Gessa G, Heinz A, Spano P. Cannabinoid receptor antagonists counteract sensorimotor gating deficits in the phencyclidine model of psychosis. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 2098-107. PMID 17299506 DOI: 10.1038/Sj.Npp.1301344  0.365
2007 Frau R, Orrù M, Fà M, Casti A, Manunta M, Fais N, Mereu G, Gessa G, Bortolato M. Effects of topiramate on the prepulse inhibition of the acoustic startle in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 320-31. PMID 16794573 DOI: 10.1038/Sj.Npp.1301115  0.381
2006 Bortolato M, Campolongo P, Mangieri RA, Scattoni ML, Frau R, Trezza V, La Rana G, Russo R, Calignano A, Gessa GL, Cuomo V, Piomelli D. Anxiolytic-like properties of the anandamide transport inhibitor AM404. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 2652-9. PMID 16541083 DOI: 10.1038/Sj.Npp.1301061  0.383
2006 La Rana G, Russo R, Campolongo P, Bortolato M, Mangieri RA, Cuomo V, Iacono A, Raso GM, Meli R, Piomelli D, Calignano A. Modulation of neuropathic and inflammatory pain by the endocannabinoid transport inhibitor AM404 [N-(4-hydroxyphenyl)-eicosa-5,8,11,14-tetraenamide]. The Journal of Pharmacology and Experimental Therapeutics. 317: 1365-71. PMID 16510698 DOI: 10.1124/Jpet.105.100792  0.305
2006 Bortolato M, Frau R, Orrù M, Casti A, Aru GN, Fà M, Manunta M, Usai A, Mereu G, Gessa GL. Prenatal exposure to a cannabinoid receptor agonist does not affect sensorimotor gating in rats. European Journal of Pharmacology. 531: 166-70. PMID 16423346 DOI: 10.1016/J.Ejphar.2005.12.017  0.363
2005 Gobbi G, Bambico FR, Mangieri R, Bortolato M, Campolongo P, Solinas M, Cassano T, Morgese MG, Debonnel G, Duranti A, Tontini A, Tarzia G, Mor M, Trezza V, Goldberg SR, et al. Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis. Proceedings of the National Academy of Sciences of the United States of America. 102: 18620-5. PMID 16352709 DOI: 10.1073/Pnas.0509591102  0.352
2005 Bortolato M, Aru GN, Frau R, Orrù M, Fà M, Manunta M, Puddu M, Mereu G, Gessa GL. Kappa opioid receptor activation disrupts prepulse inhibition of the acoustic startle in rats. Biological Psychiatry. 57: 1550-8. PMID 15953492 DOI: 10.1016/J.Biopsych.2005.02.030  0.372
2005 Bortolato M, Aru GN, Fà M, Frau R, Orrù M, Salis P, Casti A, Luckey GC, Mereu G, Gessa GL. Activation of D1, but not D2 receptors potentiates dizocilpine-mediated disruption of prepulse inhibition of the startle. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 561-74. PMID 15328529 DOI: 10.1038/Sj.Npp.1300547  0.349
2005 Bortolato M, Aru GN, Frau R, Orrù M, Luckey GC, Boi G, Gessa GL. The CB receptor agonist WIN 55,212-2 fails to elicit disruption of prepulse inhibition of the startle in Sprague-Dawley rats. Psychopharmacology. 177: 264-71. PMID 15290008 DOI: 10.1007/S00213-004-1941-4  0.366
2004 Bortolato M, Frau R, Aru GN, Orrù M, Gessa GL. Baclofen reverses the reduction in prepulse inhibition of the acoustic startle response induced by dizocilpine, but not by apomorphine. Psychopharmacology. 171: 322-30. PMID 13680072 DOI: 10.1007/S00213-003-1589-5  0.378
2001 Nava F, Carta G, Bortolato M, Gessa GL. gamma-Hydroxybutyric acid and baclofen decrease extracellular acetylcholine levels in the hippocampus via GABA(B) receptors. European Journal of Pharmacology. 430: 261-3. PMID 11711039 DOI: 10.1016/S0014-2999(01)01163-3  0.311
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