| Year |
Citation |
Score |
| 2022 |
Whitley SK, Li M, Kashem SW, Hirai T, Igyártó BZ, Knizner K, Ho J, Ferris LK, Weaver CT, Cua DJ, McGeachy MJ, Kaplan DH. Local IL-23 is required for proliferation and retention of skin-resident memory T17 cells. Science Immunology. 7: eabq3254. PMID 36367947 DOI: 10.1126/sciimmunol.abq3254 |
0.567 |
|
| 2021 |
Sherlock JP, Cua DJ. Interleukin-23 in perspective. Rheumatology (Oxford, England). 60: iv1-iv3. PMID 34668016 DOI: 10.1093/rheumatology/keab461 |
0.43 |
|
| 2020 |
Hong H, Gao M, Wu Q, Yang P, Liu S, Li H, Burrows PD, Cua D, Chen JY, Hsu HC, Mountz JD. IL-23 Promotes a Coordinated B Cell Germinal Center Program for Class-Switch Recombination to IgG2b in BXD2 Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 32554431 DOI: 10.4049/Jimmunol.2000280 |
0.488 |
|
| 2020 |
Bauché D, Joyce-Shaikh B, Fong J, Villarino AV, Ku KS, Jain R, Lee YC, Annamalai L, Yearley JH, Cua DJ. IL-23 and IL-2 activation of STAT5 is required for optimal IL-22 production in ILC3s during colitis. Science Immunology. 5. PMID 32332067 DOI: 10.1126/sciimmunol.aav1080 |
0.587 |
|
| 2019 |
Constantinides MG, Link VM, Tamoutounour S, Wong AC, Perez-Chaparro PJ, Han SJ, Chen YE, Li K, Farhat S, Weckel A, Krishnamurthy SR, Vujkovic-Cvijin I, Linehan JL, Bouladoux N, Merrill ED, ... ... Cua DJ, et al. MAIT cells are imprinted by the microbiota in early life and promote tissue repair. Science (New York, N.Y.). 366. PMID 31649166 DOI: 10.1126/Science.Aax6624 |
0.44 |
|
| 2019 |
McGeachy MJ, Cua DJ, Gaffen SL. The IL-17 Family of Cytokines in Health and Disease. Immunity. 50: 892-906. PMID 30995505 DOI: 10.1016/J.Immuni.2019.03.021 |
0.546 |
|
| 2018 |
Yan J, Cua DJ, Teng MW. IL-23 promotes the development of castration-resistant prostate cancer. Immunology and Cell Biology. PMID 30194885 DOI: 10.1111/imcb.12195 |
0.318 |
|
| 2018 |
Sabharwal SS, Rosen DB, Grein J, Tedesco D, Joyce-Shaikh B, Ueda R, Semana M, Bauer M, Bang K, Stevenson C, Cua DJ, Zuniga LA. GITR agonism enhances cellular metabolism to support CD8+ T cell proliferation and effector cytokine production in a mouse tumor model. Cancer Immunology Research. PMID 30154083 DOI: 10.1158/2326-6066.CIR-17-0632 |
0.327 |
|
| 2018 |
Bauché D, Joyce-Shaikh B, Jain R, Grein J, Ku KS, Blumenschein WM, Ganal-Vonarburg SC, Wilson DC, McClanahan TK, Malefyt RW, Macpherson AJ, Annamalai L, Yearley JH, Cua DJ. LAG3 Regulatory T Cells Restrain Interleukin-23-Producing CX3CR1 Gut-Resident Macrophages during Group 3 Innate Lymphoid Cell-Driven Colitis. Immunity. PMID 30097293 DOI: 10.1016/j.immuni.2018.07.007 |
0.608 |
|
| 2018 |
Yan J, Allen S, Vijayan D, Li XY, Harjunpää H, Takeda K, Liu J, Cua DJ, Smyth MJ, Teng MWL. Experimental lung metastases in mice are more effectively inhibited by blockade of IL23R than IL23. Cancer Immunology Research. PMID 29921599 DOI: 10.1158/2326-6066.CIR-18-0011 |
0.522 |
|
| 2016 |
Mahne A, Mauze S, Joyce-Shaikh B, Xia J, Bowman E, Beebe A, Cua D, Jain R. Dual roles for regulatory T cell depletion and co-stimulatory signaling in agonistic GITR targeting for tumor immunotherapy. Cancer Research. PMID 28122327 DOI: 10.1158/0008-5472.CAN-16-0797 |
0.623 |
|
| 2016 |
Guo Y, MacIsaac KD, Chen Y, Miller RJ, Jain R, Joyce-Shaikh B, Ferguson H, Wang IM, Cristescu R, Mudgett J, Engstrom L, Piers KJ, Baltus GA, Barr K, Zhang H, ... ... Cua DJ, et al. Inhibition of RORγT Skews TCRα Gene Rearrangement and Limits T Cell Repertoire Diversity. Cell Reports. 17: 3206-3218. PMID 28009290 DOI: 10.1016/J.Celrep.2016.11.073 |
0.316 |
|
| 2016 |
Zhou V, Agle K, Chen X, Beres A, Komorowski R, Belle L, Taylor C, Zhu F, Haribhai D, Williams CB, Verbsky J, Blumenschein W, Sadekova S, Bowman E, Ballantyne C, ... ... Cua DJ, et al. A colitogenic memory CD4+ T cell population mediates gastrointestinal graft-versus-host disease. The Journal of Clinical Investigation. PMID 27500496 DOI: 10.1172/Jci80874 |
0.482 |
|
| 2016 |
Belle L, Agle K, Zhou V, Yin-Yuan C, Komorowski R, Eastwood D, Logan B, Sun J, Ghilardi N, Cua D, Williams CB, Gaignage M, Marillier R, van Snick J, Drobyski WR. Blockade of interleukin 27 signaling reduces GVHD in mice by augmenting Treg reconstitution and stabilizing FOXP3 expression. Blood. PMID 27488350 DOI: 10.1182/Blood-2016-02-698241 |
0.586 |
|
| 2016 |
Kimura Y, Nagai N, Tsunekawa N, Sato-Matsushita M, Yoshimoto T, Cua DJ, Iwakura Y, Yagita H, Okada F, Tahara H, Saiki I, Irimura T, Hayakawa Y. IL-17A-producing CD30(+) Vδ1 T cells drive inflammation-induced cancer progression. Cancer Science. PMID 27384869 DOI: 10.1111/cas.13005 |
0.522 |
|
| 2016 |
Fujii U, Miyahara N, Taniguchi A, Waseda K, Morichika D, Kurimoto E, Koga H, Kataoka M, Gelfand EW, Cua DJ, Yoshimura A, Tanimoto M, Kanehiro A. IL-23 is Essential for the Development of Elastase-induced Pulmonary Inflammation and Emphysema. American Journal of Respiratory Cell and Molecular Biology. PMID 27351934 DOI: 10.1165/rcmb.2016-0015OC |
0.538 |
|
| 2015 |
Jain R, Chen Y, Kanno Y, Joyce-Shaikh B, Vahedi G, Hirahara K, Blumenschein WM, Sukumar S, Haines CJ, Sadekova S, McClanahan TK, McGeachy MJ, O'Shea JJ, Cua DJ. Interleukin-23-Induced Transcription Factor Blimp-1 Promotes Pathogenicity of T Helper 17 Cells. Immunity. PMID 26750311 DOI: 10.1016/J.Immuni.2015.11.009 |
0.551 |
|
| 2015 |
Lee JS, Tato CM, Joyce-Shaikh B, Gulan F, Cayatte C, Chen Y, Blumenschein WM, Judo M, Ayanoglu G, McClanahan TK, Li X, Cua DJ. Interleukin-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability. Immunity. PMID 26431948 DOI: 10.1016/j.immuni.2015.09.003 |
0.53 |
|
| 2015 |
Lee JS, Cua DJ. IL-26 AMPs up the TH17 arsenal. Nature Immunology. 16: 897-8. PMID 26287587 DOI: 10.1038/ni.3256 |
0.516 |
|
| 2015 |
Teng MW, Bowman EP, McElwee JJ, Smyth MJ, Casanova JL, Cooper AM, Cua DJ. IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases. Nature Medicine. 21: 719-29. PMID 26121196 DOI: 10.1038/Nm.3895 |
0.566 |
|
| 2015 |
Sherlock JP, Taylor PC, Buckley CD, Cua DJ. Spondyloarthropathy: interleukin 23 and disease modification. Lancet (London, England). 385: 2017-8. PMID 26009213 DOI: 10.1016/S0140-6736(15)60970-9 |
0.302 |
|
| 2015 |
Wei YL, Han A, Glanville J, Fang F, Zuniga LA, Lee JS, Cua DJ, Chien YH. A Highly Focused Antigen Receptor Repertoire Characterizes γδ T Cells That are Poised to Make IL-17 Rapidly in Naive Animals. Frontiers in Immunology. 6: 118. PMID 25852688 DOI: 10.3389/Fimmu.2015.00118 |
0.601 |
|
| 2015 |
Aychek T, Mildner A, Yona S, Kim KW, Lampl N, Reich-Zeliger S, Boon L, Yogev N, Waisman A, Cua DJ, Jung S. IL-23-mediated mononuclear phagocyte crosstalk protects mice from Citrobacter rodentium-induced colon immunopathology. Nature Communications. 6: 6525. PMID 25761673 DOI: 10.1038/Ncomms7525 |
0.544 |
|
| 2014 |
Kurtz SL, Chou AY, Kubelkova K, Cua DJ, Elkins KL. IL-23 p19 knockout mice exhibit minimal defects in responses to primary and secondary infection with Francisella tularensis LVS Plos One. 9. PMID 25296161 DOI: 10.1371/journal.pone.0109898 |
0.498 |
|
| 2014 |
Gaffen SL, Jain R, Garg AV, Cua DJ. The IL-23-IL-17 immune axis: from mechanisms to therapeutic testing. Nature Reviews. Immunology. 14: 585-600. PMID 25145755 DOI: 10.1038/Nri3707 |
0.632 |
|
| 2014 |
Li H, Hsu HC, Wu Q, Yang P, Li J, Luo B, Oukka M, Steele CH, Cua DJ, Grizzle WE, Mountz JD. IL-23 promotes TCR-mediated negative selection of thymocytes through the upregulation of IL-23 receptor and RORγt. Nature Communications. 5: 4259. PMID 25001511 DOI: 10.1038/Ncomms5259 |
0.565 |
|
| 2014 |
Sherlock JP, Buckley CD, Cua DJ. The critical role of interleukin-23 in spondyloarthropathy. Molecular Immunology. 57: 38-43. PMID 23910729 DOI: 10.1016/j.molimm.2013.06.010 |
0.462 |
|
| 2014 |
Agle K, Zhou V, Chen X, Beres A, Komorowski R, Taylor C, Haribhai D, Williams C, Verbsky J, Blumenschein W, Sadekova S, Bowman E, Weaver C, Cua D, Drobyski WR. Coordinate Expression of Beta 2 Integrins and the Interleukin 23 Receptor Define a Pathogenic CD4+ T Cell Population That Induces Colonic Inflammation during Graft Versus Host Disease Blood. 124: 537-537. DOI: 10.1182/Blood.V124.21.537.537 |
0.585 |
|
| 2014 |
Sherlock JP, Zuniga LA, Cua DJ. IL-23 in health and disease Cytokine Frontiers: Regulation of Immune Responses in Health and Disease. 179-198. DOI: 10.1007/978-4-431-54442-5_7 |
0.462 |
|
| 2013 |
Haines CJ, Chen Y, Blumenschein WM, Jain R, Chang C, Joyce-Shaikh B, Porth K, Boniface K, Mattson J, Basham B, Anderton SM, McClanahan TK, Sadekova S, Cua DJ, McGeachy MJ. Autoimmune memory T helper 17 cell function and expansion are dependent on interleukin-23. Cell Reports. 3: 1378-88. PMID 23623497 DOI: 10.1016/j.celrep.2013.03.035 |
0.545 |
|
| 2013 |
Sherlock JP, Cua DJ. Interleukin-23: a promising therapeutic target in seronegative spondyloarthropathy. Current Opinion in Pharmacology. 13: 445-8. PMID 23540587 DOI: 10.1016/j.coph.2013.03.002 |
0.539 |
|
| 2013 |
Zúñiga LA, Jain R, Haines C, Cua DJ. Th17 cell development: from the cradle to the grave. Immunological Reviews. 252: 78-88. PMID 23405896 DOI: 10.1111/imr.12036 |
0.554 |
|
| 2012 |
Cayatte C, Joyce-Shaikh B, Vega F, Boniface K, Grein J, Murphy E, Blumenschein WM, Chen S, Malinao MC, Basham B, Pierce RH, Bowman EP, McKenzie BS, Elson CO, Faubion WA, ... ... Cua D, et al. Biomarkers of Therapeutic Response in the IL-23 Pathway in Inflammatory Bowel Disease. Clinical and Translational Gastroenterology. 3: e10. PMID 23238132 DOI: 10.1038/Ctg.2012.2 |
0.523 |
|
| 2012 |
Jones SA, Sutton CE, Cua D, Mills KH. Therapeutic potential of targeting IL-17. Nature Immunology. 13: 1022-5. PMID 23080193 DOI: 10.1038/ni.2450 |
0.544 |
|
| 2012 |
Hall AO, Beiting DP, Tato C, John B, Oldenhove G, Lombana CG, Pritchard GH, Silver JS, Bouladoux N, Stumhofer JS, Harris TH, Grainger J, Wojno ED, Wagage S, Roos DS, ... ... Cua D, et al. The cytokines interleukin 27 and interferon-γ promote distinct Treg cell populations required to limit infection-induced pathology. Immunity. 37: 511-23. PMID 22981537 DOI: 10.1016/j.immuni.2012.06.014 |
0.614 |
|
| 2012 |
Suzukawa M, Morita H, Nambu A, Arae K, Shimura E, Shibui A, Yamaguchi S, Suzukawa K, Nakanishi W, Oboki K, Kajiwara N, Ohno T, Ishii A, Körner H, Cua DJ, et al. Epithelial cell-derived IL-25, but not Th17 cell-derived IL-17 or IL-17F, is crucial for murine asthma. Journal of Immunology (Baltimore, Md. : 1950). 189: 3641-52. PMID 22942422 DOI: 10.4049/jimmunol.1200461 |
0.559 |
|
| 2012 |
Uto-Konomi A, Miyauchi K, Ozaki N, Motomura Y, Suzuki Y, Yoshimura A, Suzuki S, Cua D, Kubo M. Dysregulation of suppressor of cytokine signaling 3 in keratinocytes causes skin inflammation mediated by interleukin-20 receptor-related cytokines. Plos One. 7: e40343. PMID 22792286 DOI: 10.1371/journal.pone.0040343 |
0.315 |
|
| 2012 |
Sherlock JP, Joyce-Shaikh B, Turner SP, Chao CC, Sathe M, Grein J, Gorman DM, Bowman EP, McClanahan TK, Yearley JH, Eberl G, Buckley CD, Kastelein RA, Pierce RH, Laface DM, ... Cua DJ, et al. IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4-CD8- entheseal resident T cells. Nature Medicine. 18: 1069-76. PMID 22772566 DOI: 10.1038/Nm.2817 |
0.588 |
|
| 2012 |
Savarin C, Stohlman SA, Hinton DR, Ransohoff RM, Cua DJ, Bergmann CC. IFN-γ protects from lethal IL-17 mediated viral encephalomyelitis independent of neutrophils. Journal of Neuroinflammation. 9: 104. PMID 22642802 DOI: 10.1186/1742-2094-9-104 |
0.532 |
|
| 2012 |
Tato CM, Joyce-Shaikh B, Banerjee A, Chen Y, Sathe M, Ewald SE, Liu MR, Gorman D, McClanahan TK, Phillips JH, Heyworth PG, Cua DJ. The myeloid receptor PILRβ mediates the balance of inflammatory responses through regulation of IL-27 production. Plos One. 7: e31680. PMID 22479310 DOI: 10.1371/Journal.Pone.0031680 |
0.564 |
|
| 2012 |
Joshi A, Pancari G, Cope L, Bowman EP, Cua D, Proctor RA, McNeely T. Immunization with Staphylococcus aureus iron regulated surface determinant B (IsdB) confers protection via Th17/IL17 pathway in a murine sepsis model. Human Vaccines & Immunotherapeutics. 8: 336-46. PMID 22327491 DOI: 10.4161/Hv.18946 |
0.353 |
|
| 2011 |
Haines CJ, Cua DJ. Orphan cytokine reveals IL-17 family secret. Immunity. 35: 498-500. PMID 22035844 DOI: 10.1016/j.immuni.2011.10.008 |
0.356 |
|
| 2011 |
Xu M, Morishima N, Mizoguchi I, Chiba Y, Fujita K, Kuroda M, Iwakura Y, Cua DJ, Yasutomo K, Mizuguchi J, Yoshimoto T. Regulation of the development of acute hepatitis by IL-23 through IL-22 and IL-17 production. European Journal of Immunology. 41: 2828-39. PMID 21953641 DOI: 10.1002/eji.201141291 |
0.542 |
|
| 2011 |
Chen Y, Haines CJ, Gutcher I, Hochweller K, Blumenschein WM, McClanahan T, Hämmerling G, Li MO, Cua DJ, McGeachy MJ. Foxp3(+) regulatory T cells promote T helper 17 cell development in vivo through regulation of interleukin-2. Immunity. 34: 409-21. PMID 21435588 DOI: 10.1016/j.immuni.2011.02.011 |
0.57 |
|
| 2011 |
Sawa S, Lochner M, Satoh-Takayama N, Dulauroy S, Bérard M, Kleinschek M, Cua D, Di Santo JP, Eberl G. RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota. Nature Immunology. 12: 320-6. PMID 21336274 DOI: 10.1038/Ni.2002 |
0.577 |
|
| 2011 |
Hirota K, Duarte JH, Veldhoen M, Hornsby E, Li Y, Cua DJ, Ahlfors H, Wilhelm C, Tolaini M, Menzel U, Garefalaki A, Potocnik AJ, Stockinger B. Fate mapping of IL-17-producing T cells in inflammatory responses. Nature Immunology. 12: 255-63. PMID 21278737 DOI: 10.1038/ni.1993 |
0.559 |
|
| 2011 |
Zúñiga LA, Shen WJ, Joyce-Shaikh B, Pyatnova EA, Richards AG, Thom C, Andrade SM, Cua DJ, Kraemer FB, Butcher EC. IL-17 regulates adipogenesis, glucose homeostasis, and obesity (Journal of Immunology (2010) 185, (6947-6959)) Journal of Immunology. 186: 1291. DOI: 10.4049/jimmunol.1090126 |
0.333 |
|
| 2010 |
Stumhofer JS, Tait ED, Quinn WJ, Hosken N, Spudy B, Goenka R, Fielding CA, O'Hara AC, Chen Y, Jones ML, Saris CJ, Rose-John S, Cua DJ, Jones SA, Elloso MM, et al. A role for IL-27p28 as an antagonist of gp130-mediated signaling. Nature Immunology. 11: 1119-26. PMID 21057510 DOI: 10.1038/Ni.1957 |
0.516 |
|
| 2010 |
Zúñiga LA, Shen WJ, Joyce-Shaikh B, Pyatnova EA, Richards AG, Thom C, Andrade SM, Cua DJ, Kraemer FB, Butcher EC. IL-17 regulates adipogenesis, glucose homeostasis, and obesity. Journal of Immunology (Baltimore, Md. : 1950). 185: 6947-59. PMID 21037091 DOI: 10.4049/jimmunol.1001269 |
0.427 |
|
| 2010 |
Ghoreschi K, Laurence A, Yang XP, Tato CM, McGeachy MJ, Konkel JE, Ramos HL, Wei L, Davidson TS, Bouladoux N, Grainger JR, Chen Q, Kanno Y, Watford WT, Sun HW, ... ... Cua DJ, et al. Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling. Nature. 467: 967-71. PMID 20962846 DOI: 10.1038/Nature09447 |
0.504 |
|
| 2010 |
Cua DJ, Tato CM. Innate IL-17-producing cells: the sentinels of the immune system. Nature Reviews. Immunology. 10: 479-89. PMID 20559326 DOI: 10.1038/nri2800 |
0.604 |
|
| 2010 |
Das R, Komorowski R, Hessner MJ, Subramanian H, Huettner CS, Cua D, Drobyski WR. Blockade of interleukin-23 signaling results in targeted protection of the colon and allows for separation of graft-versus-host and graft-versus-leukemia responses. Blood. 115: 5249-58. PMID 20382845 DOI: 10.1182/Blood-2009-11-255422 |
0.399 |
|
| 2010 |
Gulen MF, Kang Z, Bulek K, Youzhong W, Kim TW, Chen Y, Altuntas CZ, Sass Bak-Jensen K, McGeachy MJ, Do JS, Xiao H, Delgoffe GM, Min B, Powell JD, Tuohy VK, ... Cua DJ, et al. The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation. Immunity. 32: 54-66. PMID 20060329 DOI: 10.1016/J.Immuni.2009.12.003 |
0.55 |
|
| 2010 |
Chen Y, Hochweller K, Hämmerling G, Cua DJ, McGeachy MJ. SS1-4 Foxp3+ Tregs promote Th17 development in vivo by regulating IL-2 Cytokine. 52: 11. DOI: 10.1016/j.cyto.2010.07.051 |
0.525 |
|
| 2009 |
Tanaka S, Yoshimoto T, Naka T, Nakae S, Iwakura Y, Cua D, Kubo M. Natural occurring IL-17 producing T cells regulate the initial phase of neutrophil mediated airway responses. Journal of Immunology (Baltimore, Md. : 1950). 183: 7523-30. PMID 19890042 DOI: 10.4049/jimmunol.0803828 |
0.513 |
|
| 2009 |
Martin B, Hirota K, Cua DJ, Stockinger B, Veldhoen M. Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals. Immunity. 31: 321-30. PMID 19682928 DOI: 10.1016/j.immuni.2009.06.020 |
0.557 |
|
| 2009 |
Shichita T, Sugiyama Y, Ooboshi H, Sugimori H, Nakagawa R, Takada I, Iwaki T, Okada Y, Iida M, Cua DJ, Iwakura Y, Yoshimura A. Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury. Nature Medicine. 15: 946-50. PMID 19648929 DOI: 10.1038/nm.1999 |
0.521 |
|
| 2009 |
Dietlin TA, Cua DJ, Burke KA, Lund BT, van der Veen RC. Role of IL-23 in mobilization of immunoregulatory nitric oxide- or superoxide-producing Gr-1+ cells from bone marrow. Free Radical Biology & Medicine. 47: 357-63. PMID 19409487 DOI: 10.1016/j.freeradbiomed.2009.04.029 |
0.445 |
|
| 2009 |
Diveu C, McGeachy MJ, Boniface K, Stumhofer JS, Sathe M, Joyce-Shaikh B, Chen Y, Tato CM, McClanahan TK, de Waal Malefyt R, Hunter CA, Cua DJ, Kastelein RA. IL-27 blocks RORc expression to inhibit lineage commitment of Th17 cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 5748-56. PMID 19380822 DOI: 10.4049/Jimmunol.0801162 |
0.606 |
|
| 2009 |
Kapil P, Atkinson R, Ramakrishna C, Cua DJ, Bergmann CC, Stohlman SA. Interleukin-12 (IL-12), but not IL-23, deficiency ameliorates viral encephalitis without affecting viral control. Journal of Virology. 83: 5978-86. PMID 19339350 DOI: 10.1128/Jvi.00315-09 |
0.545 |
|
| 2009 |
Boniface K, Bak-Jensen KS, Li Y, Blumenschein WM, McGeachy MJ, McClanahan TK, McKenzie BS, Kastelein RA, Cua DJ, de Waal Malefyt R. Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling. The Journal of Experimental Medicine. 206: 535-48. PMID 19273625 DOI: 10.1084/jem.20082293 |
0.59 |
|
| 2009 |
McGeachy MJ, Chen Y, Tato CM, Laurence A, Joyce-Shaikh B, Blumenschein WM, McClanahan TK, O'Shea JJ, Cua DJ. The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo. Nature Immunology. 10: 314-24. PMID 19182808 DOI: 10.1038/ni.1698 |
0.58 |
|
| 2009 |
Yoshimura T, Sonoda KH, Ohguro N, Ohsugi Y, Ishibashi T, Cua DJ, Kobayashi T, Yoshida H, Yoshimura A. Involvement of Th17 cells and the effect of anti-IL-6 therapy in autoimmune uveitis. Rheumatology (Oxford, England). 48: 347-54. PMID 19164426 DOI: 10.1093/rheumatology/ken489 |
0.57 |
|
| 2008 |
Tato CM, Cua DJ. Reconciling id, ego, and superego within interleukin-23. Immunological Reviews. 226: 103-11. PMID 19161419 DOI: 10.1111/j.1600-065X.2008.00715.x |
0.571 |
|
| 2008 |
Diveu C, McGeachy MJ, Cua DJ. Cytokines that regulate autoimmunity. Current Opinion in Immunology. 20: 663-8. PMID 18834938 DOI: 10.1016/j.coi.2008.09.003 |
0.604 |
|
| 2008 |
Zaph C, Du Y, Saenz SA, Nair MG, Perrigoue JG, Taylor BC, Troy AE, Kobuley DE, Kastelein RA, Cua DJ, Yu Y, Artis D. Commensal-dependent expression of IL-25 regulates the IL-23-IL-17 axis in the intestine. The Journal of Experimental Medicine. 205: 2191-8. PMID 18762568 DOI: 10.1084/Jem.20080720 |
0.596 |
|
| 2008 |
McGeachy MJ, Cua DJ. Th17 cell differentiation: the long and winding road. Immunity. 28: 445-53. PMID 18400187 DOI: 10.1016/j.immuni.2008.03.001 |
0.504 |
|
| 2008 |
Luger D, Silver PB, Tang J, Cua D, Chen Z, Iwakura Y, Bowman EP, Sgambellone NM, Chan CC, Caspi RR. Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category. The Journal of Experimental Medicine. 205: 799-810. PMID 18391061 DOI: 10.1084/jem.20071258 |
0.593 |
|
| 2008 |
Tato CM, Cua DJ. SnapShot: Cytokines IV. Cell. 132: 1062.e1-2. PMID 18358817 DOI: 10.1016/j.cell.2008.02.024 |
0.395 |
|
| 2008 |
Rutitzky LI, Bazzone L, Shainheit MG, Joyce-Shaikh B, Cua DJ, Stadecker MJ. IL-23 is required for the development of severe egg-induced immunopathology in schistosomiasis and for lesional expression of IL-17. Journal of Immunology (Baltimore, Md. : 1950). 180: 2486-95. PMID 18250458 DOI: 10.4049/Jimmunol.180.4.2486 |
0.592 |
|
| 2008 |
Tato CM, Cua DJ. SnapShot: Cytokines I. Cell. 132: 324, 324.e1. PMID 18243106 DOI: 10.1016/j.cell.2008.01.001 |
0.477 |
|
| 2007 |
McGeachy MJ, Cua DJ. The link between IL-23 and Th17 cell-mediated immune pathologies. Seminars in Immunology. 19: 372-6. PMID 18319054 DOI: 10.1016/j.smim.2007.10.012 |
0.611 |
|
| 2007 |
McGeachy MJ, Bak-Jensen KS, Chen Y, Tato CM, Blumenschein W, McClanahan T, Cua DJ. TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology. Nature Immunology. 8: 1390-7. PMID 17994024 DOI: 10.1038/ni1539 |
0.551 |
|
| 2007 |
Wilson NJ, Boniface K, Chan JR, McKenzie BS, Blumenschein WM, Mattson JD, Basham B, Smith K, Chen T, Morel F, Lecron JC, Kastelein RA, Cua DJ, McClanahan TK, Bowman EP, et al. Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nature Immunology. 8: 950-7. PMID 17676044 DOI: 10.1038/ni1497 |
0.555 |
|
| 2007 |
Xiao H, Gulen MF, Qin J, Yao J, Bulek K, Kish D, Altuntas CZ, Wald D, Ma C, Zhou H, Tuohy VK, Fairchild RL, de la Motte C, Cua D, Vallance BA, et al. The Toll-interleukin-1 receptor member SIGIRR regulates colonic epithelial homeostasis, inflammation, and tumorigenesis. Immunity. 26: 461-75. PMID 17398123 DOI: 10.1016/j.immuni.2007.02.012 |
0.412 |
|
| 2007 |
Dai J, Liu B, Cua DJ, Li Z. Essential roles of IL-12 and dendritic cells but not IL-23 and macrophages in lupus-like diseases initiated by cell surface HSP gp96. European Journal of Immunology. 37: 706-15. PMID 17294405 DOI: 10.1002/eji.200636643 |
0.553 |
|
| 2007 |
Kastelein RA, Hunter CA, Cua DJ. Discovery and biology of IL-23 and IL-27: Related but functionally distinct regulators of inflammation Annual Review of Immunology. 25: 221-242. PMID 17291186 DOI: 10.1146/Annurev.Immunol.22.012703.104758 |
0.601 |
|
| 2007 |
Kleinschek MA, Owyang AM, Joyce-Shaikh B, Langrish CL, Chen Y, Gorman DM, Blumenschein WM, McClanahan T, Brombacher F, Hurst SD, Kastelein RA, Cua DJ. IL-25 regulates Th17 function in autoimmune inflammation. The Journal of Experimental Medicine. 204: 161-70. PMID 17200411 DOI: 10.1084/Jem.20061738 |
0.721 |
|
| 2007 |
McGeachy MJ, Cua D. 97 IL-23 is Vital for Effector Th17 Cell Function In Vivo Cytokine. 39: 26-27. DOI: 10.1016/J.CYTO.2007.07.102 |
0.55 |
|
| 2007 |
Diveu C, McGeachy MJ, Sathe M, Joyce-Shaikh B, McClanahan T, Gorman DM, Cua DJ, Kastelein RA. 32 IL-27P28 Protects Mice From EAE Cytokine. 39: 9. DOI: 10.1016/j.cyto.2007.07.037 |
0.433 |
|
| 2007 |
Luger D, Silver P, Cua D, Chen Z, Iwakura Y, Bowman E, Chan C, Caspi R. IL-23 and IL-17 in Pathogenesis of Experimental Ocular Autoimmunity: Requirement for IL-23 May Extend Beyond Its Role in Sustaining the IL-17 Effector Response Clinical Immunology. 123: S61. DOI: 10.1016/j.clim.2007.03.353 |
0.545 |
|
| 2006 |
Sato K, Suematsu A, Okamoto K, Yamaguchi A, Morishita Y, Kadono Y, Tanaka S, Kodama T, Akira S, Iwakura Y, Cua DJ, Takayanagi H. Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction. The Journal of Experimental Medicine. 203: 2673-82. PMID 17088434 DOI: 10.1084/jem.20061775 |
0.482 |
|
| 2006 |
Hue S, Ahern P, Buonocore S, Kullberg MC, Cua DJ, McKenzie BS, Powrie F, Maloy KJ. Interleukin-23 drives innate and T cell-mediated intestinal inflammation Journal of Experimental Medicine. 203: 2473-2483. PMID 17030949 DOI: 10.1084/Jem.20061099 |
0.718 |
|
| 2006 |
Kullberg MC, Jankovic D, Feng CG, Hue S, Gorelick PL, McKenzie BS, Cua DJ, Powrie F, Cheever AW, Maloy KJ, Sher A. IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis Journal of Experimental Medicine. 203: 2485-2494. PMID 17030948 DOI: 10.1084/Jem.20061082 |
0.742 |
|
| 2006 |
Ivanov II, McKenzie BS, Zhou L, Tadokoro CE, Lepelley A, Lafaille JJ, Cua DJ, Littman DR. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell. 126: 1121-33. PMID 16990136 DOI: 10.1016/J.Cell.2006.07.035 |
0.646 |
|
| 2006 |
Uhlig HH, McKenzie BS, Hue S, Thompson C, Joyce-Shaikh B, Stepankova R, Robinson N, Buonocore S, Tlaskalova-Hogenova H, Cua DJ, Powrie F. Differential Activity of IL-12 and IL-23 in Mucosal and Systemic Innate Immune Pathology Immunity. 25: 309-318. PMID 16919486 DOI: 10.1016/J.Immuni.2006.05.017 |
0.714 |
|
| 2006 |
Chen Y, Langrish CL, McKenzie B, Joyce-Shaikh B, Stumhofer JS, McClanahan T, Blumenschein W, Churakovsa T, Low J, Presta L, Hunter CA, Kastelein RA, Cua DJ. Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis. The Journal of Clinical Investigation. 116: 1317-26. PMID 16670771 DOI: 10.1172/Jci25308 |
0.619 |
|
| 2006 |
Yen D, Cheung J, Scheerens H, Poulet F, McClanahan T, McKenzie B, Kleinschek MA, Owyang A, Mattson J, Blumenschein W, Murphy E, Sathe M, Cua DJ, Kastelein RA, Rennick D. IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. The Journal of Clinical Investigation. 116: 1310-6. PMID 16670770 DOI: 10.1172/Jci21404 |
0.62 |
|
| 2006 |
Bowman EP, Chackerian AA, Cua DJ. Rationale and safety of anti-interleukin-23 and anti-interleukin-17A therapy. Current Opinion in Infectious Diseases. 19: 245-52. PMID 16645485 DOI: 10.1097/01.Qco.0000224818.42729.67 |
0.448 |
|
| 2006 |
Owyang AM, Zaph C, Wilson EH, Guild KJ, McClanahan T, Miller HR, Cua DJ, Goldschmidt M, Hunter CA, Kastelein RA, Artis D. Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract. The Journal of Experimental Medicine. 203: 843-9. PMID 16606667 DOI: 10.1084/Jem.20051496 |
0.591 |
|
| 2006 |
McKenzie BS, Kastelein RA, Cua DJ. Understanding the IL-23-IL-17 immune pathway Trends in Immunology. 27: 17-23. PMID 16290228 DOI: 10.1016/j.it.2005.10.003 |
0.607 |
|
| 2005 |
Langrish CL, Chen Y, Blumenschein WM, Mattson J, Basham B, Sedgwick JD, McClanahan T, Kastelein RA, Cua DJ. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. The Journal of Experimental Medicine. 201: 233-40. PMID 15657292 DOI: 10.1084/jem.20041257 |
0.63 |
|
| 2004 |
Langrish CL, McKenzie BS, Wilson NJ, De Waal Malefyt R, Kastelein RA, Cua DJ. IL-12 and IL-23: Master regulators of innate and adaptive immunity Immunological Reviews. 202: 96-105. PMID 15546388 DOI: 10.1111/j.0105-2896.2004.00214.x |
0.588 |
|
| 2004 |
Lieberman LA, Cardillo F, Owyang AM, Rennick DM, Cua DJ, Kastelein RA, Hunter CA. IL-23 provides a limited mechanism of resistance to acute toxoplasmosis in the absence of IL-12. Journal of Immunology (Baltimore, Md. : 1950). 173: 1887-93. PMID 15265921 DOI: 10.4049/Jimmunol.173.3.1887 |
0.515 |
|
| 2003 |
Murphy CA, Langrish CL, Chen Y, Blumenschein W, McClanahan T, Kastelein RA, Sedgwick JD, Cua DJ. Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation. The Journal of Experimental Medicine. 198: 1951-7. PMID 14662908 DOI: 10.1084/jem.20030896 |
0.6 |
|
| 2003 |
Dowdell KC, Cua DJ, Kirkman E, Stohlman SA. NK cells regulate CD4 responses prior to antigen encounter. Journal of Immunology (Baltimore, Md. : 1950). 171: 234-9. PMID 12817003 DOI: 10.4049/Jimmunol.171.1.234 |
0.309 |
|
| 2003 |
Cua DJ, Sherlock J, Chen Y, Murphy CA, Joyce B, Seymour B, Lucian L, To W, Kwan S, Churakova T, Zurawski S, Wiekowski M, Lira SA, Gorman D, Kastelein RA, et al. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature. 421: 744-8. PMID 12610626 DOI: 10.1038/nature01355 |
0.608 |
|
| 2002 |
Beebe AM, Cua DJ, de Waal Malefyt R. The role of interleukin-10 in autoimmune disease: systemic lupus erythematosus (SLE) and multiple sclerosis (MS). Cytokine & Growth Factor Reviews. 13: 403-12. PMID 12220553 |
0.656 |
|
| 2002 |
Barrat FJ, Cua DJ, Boonstra A, Richards DF, Crain C, Savelkoul HF, de Waal-Malefyt R, Coffman RL, Hawrylowicz CM, O'Garra A. In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. The Journal of Experimental Medicine. 195: 603-16. PMID 11877483 DOI: 10.1084/Jem.20011629 |
0.737 |
|
| 1999 |
Cua DJ, Groux H, Hinton DR, Stohlman SA, Coffman RL. Transgenic interleukin 10 prevents induction of experimental autoimmune encephalomyelitis. The Journal of Experimental Medicine. 189: 1005-10. PMID 10075984 DOI: 10.1084/Jem.189.6.1005 |
0.691 |
|
| 1997 |
Parra B, Hinton DR, Lin MT, Cua DJ, Stohlman SA. Kinetics of cytokine mRNA expression in the central nervous system following lethal and nonlethal coronavirus-induced acute encephalomyelitis. Virology. 233: 260-70. PMID 9217050 DOI: 10.1006/Viro.1997.8613 |
0.423 |
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