| Year |
Citation |
Score |
| 2023 |
Gabriel KA, Streicher JM. HSP90 inhibition in the mouse spinal cord enhances opioid signaling by suppressing an AMPK-mediated negative feedback loop. Science Signaling. 16: eade2438. PMID 37040443 DOI: 10.1126/scisignal.ade2438 |
0.484 |
|
| 2023 |
Schwarz AM, Keresztes A, Bui T, Hecksel RJ, Peña A, Lent B, Gao ZG, Gamez-Rivera M, Seekins CA, Chou K, Appel TL, Jacobson KA, Al-Obeidi FA, Streicher JM. Terpenes from Induce Antinociception in Mouse Chronic Neuropathic Pain via Activation of Spinal Cord Adenosine A Receptors. Biorxiv : the Preprint Server For Biology. PMID 37034662 DOI: 10.1101/2023.03.28.534594 |
0.383 |
|
| 2023 |
Tanguturi P, Streicher JM. The role of opioid receptors in modulating Alzheimer's Disease. Frontiers in Pharmacology. 14: 1056402. PMID 36937877 DOI: 10.3389/fphar.2023.1056402 |
0.382 |
|
| 2023 |
Szabó LZ, Tanguturi P, Goodman HJ, Sprőber S, Liu C, Al-Obeidi F, Bartlett MJ, Falk T, Kumirov VK, Heien ML, Streicher JM, Polt R. Structure-Based Design of Glycosylated Oxytocin Analogues with Improved Selectivity and Antinociceptive Activity. Acs Medicinal Chemistry Letters. 14: 163-170. PMID 36793431 DOI: 10.1021/acsmedchemlett.2c00455 |
0.566 |
|
| 2023 |
Stefanucci A, Minosi P, Pieretti S, Tanguturi P, Molnar G, Scioli G, Marinaccio L, Della Valle A, Streicher JM, Mollica A. Design of Analgesic Trivalent Peptides with Low Withdrawal Symptoms: Probing the Antinociceptive Profile of Novel Linear and Cyclic Peptides as Opioid Pan Ligands. Acs Chemical Neuroscience. 14: 506-515. PMID 36651179 DOI: 10.1021/acschemneuro.3c00005 |
0.426 |
|
| 2022 |
Stefanucci A, Della Valle A, Scioli G, Marinaccio L, Pieretti S, Minosi P, Szucs E, Benyhe S, Masci D, Tanguturi P, Chou K, Barlow D, Houseknecht K, Streicher JM, Mollica A. Discovery of κ Opioid Receptor (KOR)-Selective d-Tetrapeptides with Improved Antinociceptive Effect after Peripheral Administration. Acs Medicinal Chemistry Letters. 13: 1707-1714. PMID 36385929 DOI: 10.1021/acsmedchemlett.2c00237 |
0.395 |
|
| 2022 |
Fullerton EF, Karom MC, Streicher JM, Young LJ, Murphy AZ. Age-Induced Changes in μ-Opioid Receptor Signaling in the Midbrain Periaqueductal Gray of Male and Female Rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 35790399 DOI: 10.1523/JNEUROSCI.0355-22.2022 |
0.398 |
|
| 2022 |
Tanguturi P, Pathak V, Zhang S, Moukha-Chafiq O, Augelli-Szafran CE, Streicher JM. Correction: Tanguturi et al. Discovery of Novel Delta Opioid Receptor (DOR) Inverse Agonist and Irreversible (Non-Competitive) Antagonists. 2021, , 6693. Molecules (Basel, Switzerland). 27. PMID 35335399 DOI: 10.3390/molecules27061969 |
0.414 |
|
| 2021 |
Varga B, Streicher JM, Majumdar S. Strategies towards safer opioid analgesics - a review of old and upcoming targets. British Journal of Pharmacology. PMID 34826881 DOI: 10.1111/bph.15760 |
0.574 |
|
| 2021 |
Tanguturi P, Pathak V, Zhang S, Moukha-Chafiq O, Augelli-Szafran CE, Streicher JM. Discovery of Novel Delta Opioid Receptor (DOR) Inverse Agonist and Irreversible (Non-Competitive) Antagonists. Molecules (Basel, Switzerland). 26. PMID 34771099 DOI: 10.3390/molecules26216693 |
0.499 |
|
| 2021 |
Liktor-Busa E, Keresztes A, LaVigne J, Streicher JM, Largent-Milnes TM. Analgesic Potential of Terpenes Derived from . Pharmacological Reviews. 73: 98-126. PMID 34663685 DOI: 10.1124/pharmrev.120.000046 |
0.321 |
|
| 2021 |
Keresztes A, Olson K, Nguyen P, Lopez-Pier MA, Hecksel R, Barker NK, Liu Z, Hruby V, Konhilas J, Langlais PR, Streicher JM. Antagonism of the Mu-Delta Opioid Receptor Heterodimer Enhances Opioid Anti-Nociception by Activating Src and CaMKII Signaling. Pain. PMID 34252907 DOI: 10.1097/j.pain.0000000000002320 |
0.795 |
|
| 2021 |
Lee YS, Remesic M, Ramos-Colon C, Wu Z, LaVigne J, Molnar G, Tymecka D, Misicka A, Streicher JM, Hruby VJ, Porreca F. Multifunctional Enkephalin Analogs with a New Biological Profile: MOR/DOR Agonism and KOR Antagonism. Biomedicines. 9. PMID 34072734 DOI: 10.3390/biomedicines9060625 |
0.502 |
|
| 2021 |
LaVigne JE, Hecksel R, Keresztes A, Streicher JM. Cannabis sativa terpenes are cannabimimetic and selectively enhance cannabinoid activity. Scientific Reports. 11: 8232. PMID 33859287 DOI: 10.1038/s41598-021-87740-8 |
0.327 |
|
| 2020 |
Faouzi A, Uprety R, Gomes I, Massaly N, Keresztes AI, Le Rouzic V, Gupta A, Zhang T, Yoon HJ, Ansonoff M, Allaoa A, Pan YX, Pintar J, Morón JA, Streicher JM, et al. Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template. Journal of Medicinal Chemistry. PMID 33170687 DOI: 10.1021/acs.jmedchem.0c00901 |
0.613 |
|
| 2020 |
Morgan MM, Peecher DL, Streicher JM. Use of home cage wheel running to assess the behavioural effects of administering a mu/delta opioid receptor heterodimer antagonist for spontaneous morphine withdrawal in the rat. Behavioural Brain Research. 112953. PMID 33031872 DOI: 10.1016/j.bbr.2020.112953 |
0.504 |
|
| 2020 |
Stine C, Coleman DL, Flohrschutz AT, Thompson AL, Mishra S, Blagg BS, Largent-Milnes TM, Lei W, Streicher JM. Heat shock protein 90 inhibitors block the antinociceptive effects of opioids in mouse chemotherapy-induced neuropathy and cancer bone pain models. Pain. 161: 1798-1807. PMID 32701840 DOI: 10.1097/J.Pain.0000000000001886 |
0.524 |
|
| 2020 |
Cai S, Tuohy P, Ma C, Kitamura N, Gomez K, Zhou Y, Ran D, Bellampalli SS, Yu J, Luo S, Dorame A, Ngan Pham NY, Molnar G, Streicher JM, Patek M, et al. A modulator of the low-voltage activated T-type calcium channel that reverses HIV glycoprotein 120-, paclitaxel-, and spinal nerve ligation-induced peripheral neuropathies. Pain. PMID 32541387 DOI: 10.1097/J.Pain.0000000000001955 |
0.312 |
|
| 2020 |
Vekariya RH, Lei W, Ray A, Sainai SK, Zhang S, Molnar G, Barlow D, Karlage KL, Bilsky E, Houseknecht K, Largent-Milnes TM, Streicher JM, Ananthan S. Synthesis and Structure-Activity Relationships of 5'-Aryl-14-alkoxypyridomorphinans: Identification of a Mu Opioid Receptor Agonist/Delta Opioid Receptor Antagonist Ligand with Systemic Antinociceptive Activity and Diminished Opioid Side Effects. Journal of Medicinal Chemistry. PMID 32530286 DOI: 10.1021/Acs.Jmedchem.0C00503 |
0.674 |
|
| 2020 |
Stefanucci A, Dimmito MP, Molnar G, Streicher JM, Novellino E, Zengin G, Mollica A. Developing Cyclic Opioid Analogues: Fluorescently Labeled Bioconjugates of Biphalin. Acs Medicinal Chemistry Letters. 11: 720-726. PMID 32435376 DOI: 10.1021/Acsmedchemlett.9B00569 |
0.489 |
|
| 2020 |
Duron DI, Hanak F, Streicher JM. Daily intermittent fasting in mice enhances morphine-induced anti-nociception while mitigating reward, tolerance, and constipation. Pain. PMID 32427747 DOI: 10.1097/J.Pain.0000000000001918 |
0.595 |
|
| 2020 |
Duron DI, Lei W, Barker NK, Stine C, Mishra S, Blagg BSJ, Langlais PR, Streicher JM. Inhibition of Hsp90 in the spinal cord enhances the antinociceptive effects of morphine by activating an ERK-RSK pathway. Science Signaling. 13. PMID 32371496 DOI: 10.1126/Scisignal.Aaz1854 |
0.56 |
|
| 2020 |
Stine C, Coleman DL, Flohrschutz AT, Thompson AL, Mishra S, Blagg BS, Largent-Milnes TM, Lei W, Streicher JM. Heat shock protein 90 inhibitors block the anti-nociceptive effects of opioids in mouse chemotherapy-induced neuropathy and cancer bone pain models. Pain. PMID 32301839 DOI: 10.1097/j.pain.0000000000001886 |
0.426 |
|
| 2020 |
LaVigne J, Keresztes A, Chiem D, Streicher JM. The endomorphin-1/2 and dynorphin-B peptides display biased agonism at the mu opioid receptor. Pharmacological Reports : Pr. PMID 32112361 DOI: 10.1007/S43440-020-00061-X |
0.683 |
|
| 2020 |
Hurtado K, Keresztes A, Barker N, Langlais P, Streicher JM. Does the Mu‐Delta Opioid Receptor Heterodimer Repress Akt Kinase to Reduce Opioid Anti‐Nociception? The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06535 |
0.648 |
|
| 2020 |
Gabriel K, Duron D, Streicher J, Langlais P, Barker N. Does DUSP15 promote activation of ERK MAPK signaling after Hsp90 inhibition in the spinal cord to promote opioid anti‐nociception? The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05649 |
0.425 |
|
| 2020 |
Bejarano P, Duron D, Mishra S, Blagg BSJ, Streicher JM. Identification of the Hsp90 Isoforms and Co‐Chaperones that Repress Opioid Anti‐Nociception in the Spinal Cord The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05462 |
0.42 |
|
| 2020 |
Sieffert MM, Keresztes A, Barker N, Langlais P, Streicher J. Investigation of the Signaling Mechanisms of the Mu‐Delta Opioid Receptor Heterodimer The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05218 |
0.617 |
|
| 2020 |
Duron DI, Streicher J. Daily Intermittent Fasting in Mice Enhances Morphine Induced Anti‐Nociception while Mitigating Multiple Side Effects The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04700 |
0.48 |
|
| 2020 |
Hecksel R, LaVigne J, Streicher JM. In Defense of the “Entourage Effect”: Terpenes Found in
Cannabis sativa
Activate the Cannabinoid Receptor 1
In Vitro The Faseb Journal. 34: 1-1. DOI: 10.1096/fasebj.2020.34.s1.04622 |
0.303 |
|
| 2020 |
LaVigne J, Hecksel R, Streicher JM. In Defense of the “Entourage Effect”: Terpenes Found in Cannabis sativa Activate the Cannabinoid Receptor 1 In Vitro The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04020 |
0.411 |
|
| 2019 |
Lei W, Duron DI, Stine C, Mishra S, Blagg BSJ, Streicher JM. The Alpha Isoform of Heat Shock Protein 90 and the Co-chaperones p23 and Cdc37 Promote Opioid Anti-nociception in the Brain. Frontiers in Molecular Neuroscience. 12: 294. PMID 31849607 DOI: 10.3389/Fnmol.2019.00294 |
0.633 |
|
| 2019 |
Stefanucci A, Dimmito MP, Macedonio G, Ciarlo L, Pieretti S, Novellino E, Lei W, Barlow D, Houseknecht K, Streicher JM, Mollica A. POTENT, EFFICACIOUS AND STABLE CYCLIC OPIOID PEPTIDES WITH LONG LASTING ANTINOCICEPTIVE EFFECT AFTER PERIPHERAL ADMINISTRATION. Journal of Medicinal Chemistry. PMID 31834798 DOI: 10.1021/Acs.Jmedchem.9B01963 |
0.526 |
|
| 2019 |
Streicher JM. The role of heat shock protein 90 in regulating pain, opioid signaling, and opioid antinociception. Vitamins and Hormones. 111: 91-103. PMID 31421708 DOI: 10.1016/Bs.Vh.2019.05.010 |
0.532 |
|
| 2019 |
Lei W, Vekariya RH, Ananthan S, Streicher JM. A Novel Mu-Delta Opioid Agonist Demonstrates Enhanced Efficacy with Reduced Tolerance and Dependence in Mouse Neuropathic Pain Models. The Journal of Pain : Official Journal of the American Pain Society. PMID 31201990 DOI: 10.1016/J.Jpain.2019.05.017 |
0.566 |
|
| 2019 |
Olson KM, Duron DI, Womer D, Fell R, Streicher JM. Comprehensive molecular pharmacology screening reveals potential new receptor interactions for clinically relevant opioids. Plos One. 14: e0217371. PMID 31170174 DOI: 10.1371/Journal.Pone.0217371 |
0.793 |
|
| 2019 |
Stefanucci A, Lei W, Pieretti S, Dimmito MP, Luisi G, Novellino E, Nowakowski M, Koźmiński W, Mirzaie S, Zengin G, Streicher JM, Mollica A. Novel Cyclic Biphalin Analogues by Ruthenium-Catalyzed Ring Closing Metathesis: and Biological Profile. Acs Medicinal Chemistry Letters. 10: 450-456. PMID 30996778 DOI: 10.1021/Acsmedchemlett.8B00495 |
0.462 |
|
| 2019 |
Stefanucci A, Lei W, Pieretti S, Novellino E, Dimmito MP, Marzoli F, Streicher JM, Mollica A. On resin click-chemistry-mediated synthesis of novel enkephalin analogues with potent anti-nociceptive activity. Scientific Reports. 9: 5771. PMID 30962495 DOI: 10.1038/S41598-019-42289-5 |
0.478 |
|
| 2019 |
Shan Z, Cai S, Yu J, Zhang Z, Vallecillo TGM, Serafini MJ, Thomas AM, Pham NYN, Bellampalli SS, Moutal A, Zhou Y, Xu GB, Xu YM, Luo S, Patek M, ... Streicher JM, et al. Reversal of peripheral neuropathic pain by the small-molecule natural product physalin F via block of CaV2.3 (R-type) and CaV2.2 (N-type) voltage-gated calcium channels. Acs Chemical Neuroscience. PMID 30946560 DOI: 10.1021/Acschemneuro.9B00166 |
0.42 |
|
| 2019 |
Khanna R, Yu J, Yang X, Moutal A, Chefdeville A, Gokhale V, Shuja Z, Chew LA, Bellampalli SS, Luo S, François-Moutal L, Serafini MJ, Ha T, Perez-Miller S, Park KD, ... ... Streicher JM, et al. Targeting the CaVα-CaVβ interaction yields an antagonist of the N-type CaV2.2 channel with broad antinociceptive efficacy. Pain. PMID 30933958 DOI: 10.1097/J.Pain.0000000000001524 |
0.382 |
|
| 2019 |
Streicher JM. The Role of Heat Shock Proteins in Regulating Receptor Signal Transduction. Molecular Pharmacology. 95: 468-474. PMID 30670482 DOI: 10.1124/Mol.118.114652 |
0.342 |
|
| 2018 |
Cai S, Bellampalli SS, Yu J, Li W, Ji Y, Wijeratne EMK, Dorame A, Luo S, Shan Z, Khanna M, Moutal A, Streicher JM, Gunatilaka AAL, Khanna R. (-)-Hardwickiic acid and Hautriwaic acid induce antinociception via blockade of tetrodotoxin-sensitive voltage-dependent sodium channels. Acs Chemical Neuroscience. PMID 30525440 DOI: 10.1021/Acschemneuro.8B00617 |
0.402 |
|
| 2018 |
Bellampalli SS, Ji Y, Moutal A, Cai S, Wijeratne EMK, Gandini MA, Yu J, Chefdeville A, Dorame A, Chew LA, Madura CL, Luo S, Molnar G, Khanna M, Streicher JM, et al. Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury-associated peripheral sensory neuropathy via block of N- and T-type calcium channels. Pain. PMID 30169422 DOI: 10.1097/J.Pain.0000000000001385 |
0.411 |
|
| 2018 |
Olson KM, Keresztes A, Tashiro JK, Daconta LV, Hruby VJ, Streicher JM. Synthesis and Evaluation of a Novel Bivalent Selective Antagonist for the Mu-Delta Opioid Receptor Heterodimer that Reduces Morphine Withdrawal in Mice. Journal of Medicinal Chemistry. PMID 29939746 DOI: 10.1021/Acs.Jmedchem.8B00403 |
0.775 |
|
| 2018 |
Edwards KA, Havelin JJ, Mcintosh MI, Ciccone HA, Pangilinan K, Imbert I, Largent-Milnes TM, King T, Vanderah TW, Streicher JM. A Kappa Opioid Receptor Agonist Blocks Bone Cancer Pain Without Altering Bone Loss, Tumor Size, or Cancer Cell Proliferation in a Mouse Model of Cancer-Induced Bone Pain. The Journal of Pain : Official Journal of the American Pain Society. PMID 29371114 DOI: 10.1016/J.Jpain.2018.01.002 |
0.451 |
|
| 2018 |
Streicher J, Duron D, Lei W, Stine C, Blagg B. Heat shock protein 90 promotes opioid anti-nociception in the brain and represses opioid anti-nociception in the spinal cord through the differential regulation of ERK MAPK signaling The Journal of Pain. 19: S100-S101. DOI: 10.1016/J.Jpain.2017.12.227 |
0.509 |
|
| 2017 |
Keresztes A, Streicher JM. Synergistic interaction of the cannabinoid and death receptor systems - a potential target for future cancer therapies? Febs Letters. 591: 3235-3251. PMID 28948607 DOI: 10.1002/1873-3468.12863 |
0.373 |
|
| 2017 |
Streicher JM, Bilsky EJ. Peripherally Acting µ-Opioid Receptor Antagonists for the Treatment of Opioid-Related Side Effects: Mechanism of Action and Clinical Implications. Journal of Pharmacy Practice. 897190017732263. PMID 28946783 DOI: 10.1177/0897190017732263 |
0.669 |
|
| 2017 |
Starnowska J, Costante R, Guillemyn K, Popiolek-Barczyk K, Chung NN, Lemieux C, Keresztes A, Van Duppen J, Mollica A, Streicher JM, Vanden Broeck J, Schiller PW, Tourwé D, Mika J, Ballet S, et al. Analgesic properties of opioid/NK1 multitarget ligands with distinct in vitro profiles in naive and chronic constriction injury (CCI)-mice. Acs Chemical Neuroscience. PMID 28699350 DOI: 10.1021/Acschemneuro.7B00226 |
0.631 |
|
| 2017 |
Stefanucci A, Lei W, Hruby VJ, Macedonio G, Luisi G, Carradori S, Streicher JM, Mollica A. Fluorescent-labeled bioconjugates of the opioid peptides biphalin and DPDPE incorporating fluorescein-maleimide linkers. Future Medicinal Chemistry. PMID 28635314 DOI: 10.4155/Fmc-2016-0232 |
0.549 |
|
| 2017 |
Lei W, Mullen N, McCarthy S, Brann C, Richard P, Cormier J, Edwards K, Bilsky EJ, Streicher JM. Heat shock protein 90 (Hsp90) promotes opioid-induced anti-nociception by an ERK Mitogen Activated Protein Kinase (MAPK) mechanism in mouse brain. The Journal of Biological Chemistry. PMID 28450396 DOI: 10.1074/Jbc.M116.769489 |
0.586 |
|
| 2017 |
Xie JY, De Felice M, Kopruszinski CM, Eyde N, LaVigne J, Remeniuk B, Hernandez P, Yue X, Goshima N, Ossipov M, King T, Streicher JM, Navratilova E, Dodick D, Rosen H, et al. Kappa opioid receptor antagonists: A possible new class of therapeutics for migraine prevention. Cephalalgia : An International Journal of Headache. 333102417702120. PMID 28376659 DOI: 10.1177/0333102417702120 |
0.458 |
|
| 2017 |
Olson KM, Lei W, Keresztes A, LaVigne J, Streicher JM. Novel Molecular Strategies and Targets for Opioid Drug Discovery for the Treatment of Chronic Pain. The Yale Journal of Biology and Medicine. 90: 97-110. PMID 28356897 |
0.796 |
|
| 2017 |
Streicher J, Lei W, Mullen N, Brann C, Cornier J, Bilsky E. (205) Heat shock protein 90 promotes opioid-induced anti-nociception by an ERK Mitogen Activated Protein Kinase mechanism in mouse brain The Journal of Pain. 18: S27. DOI: 10.1016/J.Jpain.2017.02.368 |
0.442 |
|
| 2016 |
Edwards K, Bogusz J, LaVigne J, Pangilinan K, Streicher J. (285) Phosphatidylethanolamine-binding protein regulates Mu opioid receptor induced βarrestin2 recruitment and downstream signaling. The Journal of Pain : Official Journal of the American Pain Society. 17: S47. PMID 28162521 DOI: 10.1016/J.Jpain.2016.01.191 |
0.604 |
|
| 2016 |
Ramos-Colon CN, Lee YS, Remesic MV, Hall SM, LaVigne J, Davis P, Sandweiss AJ, McIntosh MI, Hanson J, Largent-Milnes TM, Vanderah TW, Streicher JM, Porreca F, Hruby VJ. Structure Activity Relationships of [des-Arg(7)]- Dynorphin A Analogues at the Kappa Opioid Receptor. Journal of Medicinal Chemistry. PMID 27797517 DOI: 10.1021/Acs.Jmedchem.6B01411 |
0.683 |
|
| 2015 |
Zhang Y, Williams DA, Zaidi SA, Yuan Y, Braithwaite A, Bilsky EJ, Dewey WL, Akbarali HI, Streicher JM, Selley DE. 17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-(4'-pyridylcarboxamido)morphinan (NAP) modulating the mu opioid receptor in a biased fashion. Acs Chemical Neuroscience. PMID 26716358 DOI: 10.1021/Acschemneuro.5B00245 |
0.514 |
|
| 2015 |
Stevenson GW, Luginbuhl A, Dunbar C, LaVigne J, Dutra J, Atherton P, Bell B, Cone K, Giuvelis D, Polt R, Streicher JM, Bilsky EJ. The mixed-action delta/mu opioid agonist MMP-2200 does not produce conditioned place preference but does maintain drug self-administration in rats, and induces in vitro markers of tolerance and dependence. Pharmacology, Biochemistry, and Behavior. 132: 49-55. PMID 25735493 DOI: 10.1016/J.Pbb.2015.02.022 |
0.579 |
|
| 2015 |
Frankowski KJ, Slauson SR, Lovell KM, Phillips AM, Streicher JM, Zhou L, Whipple DA, Schoenen FJ, Prisinzano TE, Bohn LM, Aubé J. Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif. Bioorganic & Medicinal Chemistry. 23: 3948-56. PMID 25593096 DOI: 10.1016/J.Bmc.2014.12.033 |
0.571 |
|
| 2014 |
Zhang Y, Braithwaite A, Yuan Y, Streicher JM, Bilsky EJ. Behavioral and cellular pharmacology characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan (NAQ) as a mu opioid receptor selective ligand. European Journal of Pharmacology. 736: 124-30. PMID 24815322 DOI: 10.1016/J.Ejphar.2014.04.041 |
0.674 |
|
| 2014 |
Schmid CL, Streicher JM, Meltzer HY, Bohn LM. Clozapine acts as an agonist at serotonin 2A receptors to counter MK-801-induced behaviors through a βarrestin2-independent activation of Akt. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1902-13. PMID 24531562 DOI: 10.1038/Npp.2014.38 |
0.439 |
|
| 2013 |
Zhou L, Lovell KM, Frankowski KJ, Slauson SR, Phillips AM, Streicher JM, Stahl E, Schmid CL, Hodder P, Madoux F, Cameron MD, Prisinzano TE, Aubé J, Bohn LM. Development of functionally selective, small molecule agonists at kappa opioid receptors. The Journal of Biological Chemistry. 288: 36703-16. PMID 24187130 DOI: 10.1074/Jbc.M113.504381 |
0.568 |
|
| 2013 |
Schmid CL, Streicher JM, Groer CE, Munro TA, Zhou L, Bohn LM. Functional selectivity of 6'-guanidinonaltrindole (6'-GNTI) at κ-opioid receptors in striatal neurons. The Journal of Biological Chemistry. 288: 22387-98. PMID 23775075 DOI: 10.1074/Jbc.M113.476234 |
0.481 |
|
| 2012 |
Frankowski KJ, Hedrick MP, Gosalia P, Li K, Shi S, Whipple D, Ghosh P, Prisinzano TE, Schoenen FJ, Su Y, Vasile S, Sergienko E, Gray W, Hariharan S, Milan L, ... ... Streicher JM, et al. Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy. Acs Chemical Neuroscience. 3: 221-236. PMID 22737280 DOI: 10.1021/Cn200128X |
0.525 |
|
| 2012 |
Béguin C, Potuzak J, Xu W, Liu-Chen LY, Streicher JM, Groer CE, Bohn LM, Carlezon WA, Cohen BM. Differential signaling properties at the kappa opioid receptor of 12-epi-salvinorin A and its analogues. Bioorganic & Medicinal Chemistry Letters. 22: 1023-6. PMID 22204910 DOI: 10.1016/J.Bmcl.2011.11.128 |
0.616 |
|
| 2011 |
Tarselli MA, Raehal KM, Brasher AK, Streicher JM, Groer CE, Cameron MD, Bohn LM, Micalizio GC. Synthesis of conolidine, a potent non-opioid analgesic for tonic and persistent pain. Nature Chemistry. 3: 449-53. PMID 21602859 DOI: 10.1038/Nchem.1050 |
0.565 |
|
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