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Natalie Jäger - Publications

Affiliations: 
Stanford University, Palo Alto, CA 
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39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Thatikonda V, Islam SMA, Autry RJ, Jones BC, Gröbner SN, Warsow G, Hutter B, Huebschmann D, Fröhling S, Kool M, Blattner-Johnson M, Jones DTW, Alexandrov LB, Pfister SM, Jäger N. Comprehensive analysis of mutational signatures reveals distinct patterns and molecular processes across 27 pediatric cancers. Nature Cancer. PMID 36702933 DOI: 10.1038/s43018-022-00509-4  0.406
2022 Tsai JW, Cejas P, Wang DK, Patel S, Wu DW, Arounleut P, Wei X, Zhou N, Syamala S, Dubois FPB, Crane A, Pelton K, Vogelzang J, Sousa C, Baguette A, et al. FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits. Cancer Research. PMID 35802025 DOI: 10.1158/0008-5472.CAN-22-0671  0.357
2021 Daub JT, Amini S, Kersjes DJE, Ma X, Jäger N, Zhang J, Pfister SM, Holstege FCP, Kemmeren P. A systematic analysis of genetic interactions and their underlying biology in childhood cancer. Communications Biology. 4: 1139. PMID 34615983 DOI: 10.1038/s42003-021-02647-4  0.312
2021 Fisher MJ, Jones DTW, Li Y, Guo X, Sonawane PS, Waanders AJ, Phillips JJ, Weiss WA, Resnick AC, Gosline S, Banerjee J, Guinney J, Gnekow A, Kandels D, Foreman NK, et al. Integrated molecular and clinical analysis of low-grade gliomas in children with neurofibromatosis type 1 (NF1). Acta Neuropathologica. PMID 33585982 DOI: 10.1007/s00401-021-02276-5  0.305
2020 Waszak SM, Robinson GW, Gudenas BL, Smith KS, Forget A, Kojic M, Garcia-Lopez J, Hadley J, Hamilton KV, Indersie E, Buchhalter I, Kerssemakers J, Jäger N, Sharma T, Rausch T, et al. Germline Elongator mutations in Sonic Hedgehog medulloblastoma. Nature. 580: 396-401. PMID 32296180 DOI: 10.1038/S41586-020-2164-5  0.449
2020 Nabbi A, Sun P, Sumedha S, Zhu K, Yang SYC, Paulson JN, Kool M, Rathi K, Kalletla K, Raman P, Zhu Y, Resnick AC, Jones DTW, Jäger N, Pfister SM, et al. Abstract PR06: The immunogenomic landscape of pediatric primary solid tumors Cancer Research. 80. DOI: 10.1158/1538-7445.Pedca19-Pr06  0.457
2020 Sharma T, Schwalbe EC, Williamson DW, Sill M, Hovestadt V, Mynarek M, Rutkowski S, Robinson GW, Gajjar A, Cavalli F, Ramaswamy V, Taylor MD, Lindsey JC, Hill RM, Jäger N, et al. Abstract B73: Second-generation molecular subgrouping of medulloblastoma: An international meta-analysis of Group 3 and Group 4 subtypes Cancer Research. 80. DOI: 10.1158/1538-7445.Pedca19-B73  0.331
2019 Begemann M, Waszak SM, Robinson GW, Jäger N, Sharma T, Knopp C, Kraft F, Moser O, Mynarek M, Guerrini-Rousseau L, Brugieres L, Varlet P, Pietsch T, Bowers DC, Chintagumpala M, et al. Germline Mutations Predispose to Pediatric Medulloblastoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO1900577. PMID 31609649 DOI: 10.1200/Jco.19.00577  0.369
2019 Gruber JJ, Chen J, Geller B, Jäger N, Lipchik AM, Wang G, Kurian AW, Ford JM, Snyder MP. Chromatin Remodeling in Response to BRCA2-Crisis. Cell Reports. 28: 2182-2193.e6. PMID 31433991 DOI: 10.1016/J.Celrep.2019.07.057  0.625
2019 Johann PD, Jäger N, Pfister SM, Sill M. RF_Purify: a novel tool for comprehensive analysis of tumor-purity in methylation array data based on random forest regression. Bmc Bioinformatics. 20: 428. PMID 31419933 DOI: 10.1186/S12859-019-3014-Z  0.351
2019 Jones DTW, Banito A, Grünewald TGP, Haber M, Jäger N, Kool M, Milde T, Molenaar JJ, Nabbi A, Pugh TJ, Schleiermacher G, Smith MA, Westermann F, Pfister SM. Molecular characteristics and therapeutic vulnerabilities across paediatric solid tumours. Nature Reviews. Cancer. PMID 31300807 DOI: 10.1038/S41568-019-0169-X  0.373
2019 Chen J, Haanpää MK, Gruber JJ, Jäger N, Ford JM, Snyder MP. High-Resolution Bisulfite-Sequencing of Peripheral Blood DNA Methylation in Early-Onset and Familial Risk Breast Cancer Patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31175093 DOI: 10.1158/1078-0432.Ccr-18-2423  0.727
2019 Schramm K, Iskar M, Statz B, Jäger N, Haag D, Słabicki M, Pfister SM, Zapatka M, Gronych J, Jones DTW, Lichter P. DECIPHER pooled shRNA library screen identifies PP2A and FGFR signaling as potential therapeutic targets for DIPGs. Neuro-Oncology. PMID 30943283 DOI: 10.1093/Neuonc/Noz057  0.414
2019 van Tilburg CM, Witt R, Pajtler KW, Christoph P, Poschke I, Platten M, Harting I, Sedlaczek O, Freitag A, Meyrath D, Taylor L, Balasubramanian GP, Jäger N, Pfaff E, Worst BC, et al. INFORM2 exploratory multinational phase I/II combination study of nivolumab and entinostat in children and adolescents with refractory high-risk malignancies: INFORM2 NivEnt. Journal of Clinical Oncology. 37: TPS10065-TPS10065. DOI: 10.1200/Jco.2019.37.15_Suppl.Tps10065  0.341
2019 Gruber J, Chen J, Geller B, Jager N, Lipchik A, Snyder M. Abstract P3-05-02: Not presented Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P3-05-02  0.674
2019 Nabbi A, Jäger N, Sudhaman S, Sun P, Yang SYC, Zhu K, Kool M, Rathi K, Kalletla K, Raman P, Zhu Y, Paulson JN, Jones DT, Tabori U, Resnick AC, et al. Abstract 2891: Landscape of infiltrating immune repertoire in pediatric solid tumors Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-2891  0.327
2018 Gruber JJ, Juntilla MM, Yang S, Geller B, Jager N, Lin C, Lipchik AM, Chen J, Ram A, Vinayak S, Telli ML, West RB, Ford JM, Snyder MP. Abstract 4749: VISTA immune checkpoint deregulation in human triple-negative breast cancer Cancer Research. 78: 4749-4749. DOI: 10.1158/1538-7445.Am2018-4749  0.735
2018 Jäger N, Brabetz S, Pfister S, Kool M. Mbrs-33. Rna-Sequencing Of Medulloblastoma Patient-Derived Orthotopic Xenograft (Pdox) Models Enables Identification Of Both Tumor And Microenvironment Specific Biomarkers Neuro-Oncology. 20. DOI: 10.1093/Neuonc/Noy059.478  0.315
2017 Northcott PA, Buchhalter I, Morrissy AS, Hovestadt V, Weischenfeldt J, Ehrenberger T, Gröbner S, Segura-Wang M, Zichner T, Rudneva VA, Warnatz HJ, Sidiropoulos N, Phillips AH, Schumacher S, Kleinheinz K, et al. The whole-genome landscape of medulloblastoma subtypes. Nature. 547: 311-317. PMID 28726821 DOI: 10.1038/Nature22973  0.477
2015 Alioto TS, Buchhalter I, Derdak S, Hutter B, Eldridge MD, Hovig E, Heisler LE, Beck TA, Simpson JT, Tonon L, Sertier AS, Patch AM, Jäger N, Ginsbach P, Drews R, et al. A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing. Nature Communications. 6: 10001. PMID 26647970 DOI: 10.1038/Ncomms10001  0.393
2014 Northcott PA, Lee C, Zichner T, Stütz AM, Erkek S, Kawauchi D, Shih DJ, Hovestadt V, Zapatka M, Sturm D, Jones DT, Kool M, Remke M, Cavalli FM, Zuyderduyn S, et al. Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma. Nature. 511: 428-34. PMID 25043047 DOI: 10.1038/Nature13379  0.382
2014 Hovestadt V, Jones DT, Picelli S, Wang W, Kool M, Northcott PA, Sultan M, Stachurski K, Ryzhova M, Warnatz HJ, Ralser M, Brun S, Bunt J, Jäger N, Kleinheinz K, et al. Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing. Nature. 510: 537-41. PMID 24847876 DOI: 10.1038/Nature13268  0.397
2014 Kool M, Jones DT, Jäger N, Northcott PA, Pugh TJ, Hovestadt V, Piro RM, Esparza LA, Markant SL, Remke M, Milde T, Bourdeaut F, Ryzhova M, Sturm D, Pfaff E, et al. Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition. Cancer Cell. 25: 393-405. PMID 24651015 DOI: 10.1016/J.Ccr.2014.02.004  0.364
2014 Mack SC, Witt H, Piro RM, Gu L, Zuyderduyn S, Stütz AM, Wang X, Gallo M, Garzia L, Zayne K, Zhang X, Ramaswamy V, Jäger N, Jones DT, Sill M, et al. Epigenomic alterations define lethal CIMP-positive ependymomas of infancy. Nature. 506: 445-50. PMID 24553142 DOI: 10.1038/Nature13108  0.393
2014 Kool M, Jäger N, Sturm D, Jones DTW, Hoverstadt V, Buchhalter I, Johann P, Schmidt C, Ryzhova M, Northcott PA, Landgraf P, Remke M, Taylor MD, Hasselblatt M, Schüller U, et al. Abstract 3093: Unravelling the biology of aggressive and therapy-resistant embryonal tumors with multilayered rosettes (ETMR) Cancer Research. 74: 3093-3093. DOI: 10.1158/1538-7445.Am2014-3093  0.425
2013 Jäger N, Schlesner M, Jones DT, Raffel S, Mallm JP, Junge KM, Weichenhan D, Bauer T, Ishaque N, Kool M, Northcott PA, Korshunov A, Drews RM, Koster J, Versteeg R, et al. Hypermutation of the inactive X chromosome is a frequent event in cancer. Cell. 155: 567-81. PMID 24139898 DOI: 10.1016/J.Cell.2013.09.042  0.399
2013 Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SA, Behjati S, Biankin AV, Bignell GR, Bolli N, Borg A, Børresen-Dale AL, Boyault S, Burkhardt B, Butler AP, Caldas C, Davies HR, et al. Signatures of mutational processes in human cancer. Nature. 500: 415-21. PMID 23945592 DOI: 10.1038/Nature12477  0.445
2013 Jones DT, Hutter B, Jäger N, Korshunov A, Kool M, Warnatz HJ, Zichner T, Lambert SR, Ryzhova M, Quang DA, Fontebasso AM, Stütz AM, Hutter S, Zuckermann M, Sturm D, et al. Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. Nature Genetics. 45: 927-32. PMID 23817572 DOI: 10.1038/Ng.2682  0.445
2013 Weischenfeldt J, Simon R, Feuerbach L, Schlangen K, Weichenhan D, Minner S, Wuttig D, Warnatz HJ, Stehr H, Rausch T, Jäger N, Gu L, Bogatyrova O, Stütz AM, Claus R, et al. Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer. Cancer Cell. 23: 159-70. PMID 23410972 DOI: 10.1016/J.Ccr.2013.01.002  0.337
2013 Reuss DE, Piro RM, Jones DT, Simon M, Ketter R, Kool M, Becker A, Sahm F, Pusch S, Meyer J, Hagenlocher C, Schweizer L, Capper D, Kickingereder P, Mucha J, et al. Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations. Acta Neuropathologica. 125: 351-8. PMID 23404370 DOI: 10.1007/S00401-013-1093-X  0.382
2013 Jones DT, Hutter B, Jäger N, Korshunov A, Kool M, Lambert SR, Quang DAK, Fontebasso AM, Ryzhova M, Warnatz H, Zichner T, Korbel JO, Wolf S, Yaspo M, Ligon KL, et al. Abstract 4594: Recurrent FGFR1 hotspot mutations represent a novel therapeutic target in childhood astrocytoma. Cancer Research. 73: 4594-4594. DOI: 10.1158/1538-7445.Am2013-4594  0.443
2013 Haller F, Agaimy A, Moskalev EA, Jäger N, Broers B, Wiemann S, Hartmann A. Abstract 2017: Exome sequencing reveals novel mutations in a GIST and a paraganglioma occurring simultaneously in a patient with complete form of Carney triad. Cancer Research. 73: 2017-2017. DOI: 10.1158/1538-7445.Am2013-2017  0.414
2013 Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SAJR, Behjati S, Biankin AV, Bignell GR, Bolli N, Borg A, Børresen-Dale A, Boyault S, Burkhardt B, Butler AP, Caldas C, Davies HR, et al. Corrigendum: Signatures of mutational processes in human cancer Nature. 502: 258-258. DOI: 10.1038/Nature12666  0.329
2012 Jones DT, Jäger N, Kool M, Zichner T, Hutter B, Sultan M, Cho YJ, Pugh TJ, Hovestadt V, Stütz AM, Rausch T, Warnatz HJ, Ryzhova M, Bender S, Sturm D, et al. Dissecting the genomic complexity underlying medulloblastoma. Nature. 488: 100-5. PMID 22832583 DOI: 10.1038/Nature11284  0.397
2012 Pugh TJ, Weeraratne SD, Archer TC, Pomeranz Krummel DA, Auclair D, Bochicchio J, Carneiro MO, Carter SL, Cibulskis K, Erlich RL, Greulich H, Lawrence MS, Lennon NJ, McKenna A, Meldrim J, et al. Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations. Nature. 488: 106-10. PMID 22820256 DOI: 10.1038/Nature11329  0.386
2012 Schwartzentruber J, Korshunov A, Liu XY, Jones DT, Pfaff E, Jacob K, Sturm D, Fontebasso AM, Quang DA, Tönjes M, Hovestadt V, Albrecht S, Kool M, Nantel A, Konermann C, et al. Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature. 482: 226-31. PMID 22286061 DOI: 10.1038/Nature10833  0.385
2012 Rausch T, Jones DT, Zapatka M, Stütz AM, Zichner T, Weischenfeldt J, Jäger N, Remke M, Shih D, Northcott PA, Pfaff E, Tica J, Wang Q, Massimi L, Witt H, et al. Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations. Cell. 148: 59-71. PMID 22265402 DOI: 10.1016/J.Cell.2011.12.013  0.443
2012 Schwartzentruber J, Korshunov A, Liu X, Jones DTW, Pfaff E, Jacob K, Sturm D, Fontebasso AM, Quang DK, Tönjes M, Hovestadt V, Albrecht S, Kool M, Nantel A, Konermann C, et al. Erratum: Corrigendum: Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma Nature. 484: 130-130. DOI: 10.1038/Nature11026  0.355
2011 Jones D, Zapatka M, Jäger N, Wang Q, Stuetz A, Rausch T, Benes V, Blake J, Korshunov A, Schmidt M, Bartholomae C, Witt O, Taylor M, Kalle Cv, Brors B, et al. First Results from the International Cancer Genome Consortium PedBrain Tumor Project on Whole-Genome Deep Sequencing in Medulloblastoma Klinische PäDiatrie. 223. DOI: 10.1055/S-0031-1292588  0.36
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