Doris Kretzschmar - Publications

Oregon Health and Science University, Portland, OR 
Drosophila neurodegeneration

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Law AD, Cassar M, Long DM, Chow ES, Giebultowicz JM, Venkataramanan A, Strauss R, Kretzschmar D. FTD-associated mutations in Tau result in a combination of dominant and recessive phenotypes. Neurobiology of Disease. 170: 105770. PMID 35588988 DOI: 10.1016/j.nbd.2022.105770  0.78
2022 Kretzschmar D. PNPLA6/NTE, an Evolutionary Conserved Phospholipase Linked to a Group of Complex Human Diseases. Metabolites. 12. PMID 35448471 DOI: 10.3390/metabo12040284  0.399
2020 Long DM, Frame AK, Reardon PN, Cumming RC, Hendrix DA, Kretzschmar D, Giebultowicz JM. Lactate dehydrogenase expression modulates longevity and neurodegeneration in . Aging. 12. PMID 32484787 DOI: 10.18632/aging.103373  0.379
2020 Cassar M, Law AD, Chow ES, Giebultowicz JM, Kretzschmar D. Disease-Associated Mutant Tau Prevents Circadian Changes in the Cytoskeleton of Central Pacemaker Neurons. Frontiers in Neuroscience. 14: 232. PMID 32292325 DOI: 10.3389/Fnins.2020.00232  0.756
2019 Sunderhaus ER, Law AD, Kretzschmar D. Disease-Associated PNPLA6 Mutations Maintain Partial Functions When Analyzed in . Frontiers in Neuroscience. 13: 1207. PMID 31780887 DOI: 10.3389/Fnins.2019.01207  0.453
2019 Sunderhaus ER, Law AD, Kretzschmar D. ER responses play a key role in Swiss-Cheese/Neuropathy Target Esterase-associated neurodegeneration. Neurobiology of Disease. 104520. PMID 31233884 DOI: 10.1016/J.Nbd.2019.104520  0.326
2018 Rieche F, Carmine-Simmen K, Poeck B, Kretzschmar D, Strauss R. Drosophila Full-Length Amyloid Precursor Protein Is Required for Visual Working Memory and Prevents Age-Related Memory Impairment. Current Biology : Cb. PMID 29478851 DOI: 10.1016/J.Cub.2018.01.077  0.365
2018 Cassar M, Sunderhaus E, Wentzell JS, Kuntz S, Strauss R, Kretzschmar D. The PKA-C3 catalytic subunit is required in two pairs of interneurons for successful mating of Drosophila. Scientific Reports. 8: 2458. PMID 29410515 DOI: 10.1038/S41598-018-20697-3  0.794
2017 Louis Sam Titus ASC, Yusuff T, Cassar M, Thomas E, Kretzschmar D, D'Mello SR. Reduced expression of Foxp1 as a contributing factor in Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28550168 DOI: 10.1523/Jneurosci.3612-16.2017  0.777
2017 McFerrin J, Patton BL, Sunderhaus ER, Kretzschmar D. NTE/PNPLA6 is expressed in mature Schwann cells and is required for glial ensheathment of Remak fibers. Glia. PMID 28206686 DOI: 10.1002/Glia.23127  0.408
2017 Fahey MC, Maclennan AH, Kretzschmar D, Gecz J, Kruer MC. The genetic basis of cerebral palsy. Developmental Medicine and Child Neurology. PMID 28042670 DOI: 10.1111/Dmcn.13363  0.308
2016 Sunderhaus ER, Kretzschmar D. Mass Histology to Quantify Neurodegeneration in Drosophila. Journal of Visualized Experiments : Jove. PMID 28060320 DOI: 10.3791/54809  0.454
2016 Ramaker JM, Cargill RS, Swanson TL, Quirindongo H, Cassar M, Kretzschmar D, Copenhaver PF. Amyloid Precursor Proteins Are Dynamically Trafficked and Processed during Neuronal Development. Frontiers in Molecular Neuroscience. 9: 130. PMID 27932950 DOI: 10.3389/Fnmol.2016.00130  0.801
2016 Cassar M, Kretzschmar D. Analysis of Amyloid Precursor Protein Function in Drosophila melanogaster. Frontiers in Molecular Neuroscience. 9: 61. PMID 27507933 DOI: 10.3389/Fnmol.2016.00061  0.8
2015 Dutta S, Rieche F, Eckl N, Duch C, Kretzschmar D. Glial expression of Swiss-cheese (SWS), the Drosophila orthologue of Neuropathy Target Esterase, is required for neuronal ensheathment and function. Disease Models & Mechanisms. PMID 26634819 DOI: 10.1242/Dmm.022236  0.537
2015 Blake MR, Holbrook SD, Kotwica-Rolinska J, Chow ES, Kretzschmar D, Giebultowicz JM. Manipulations of amyloid precursor protein cleavage disrupt the circadian clock in aging Drosophila. Neurobiology of Disease. 77: 117-26. PMID 25766673 DOI: 10.1016/J.Nbd.2015.02.012  0.457
2015 Kmoch S, Majewski J, Ramamurthy V, Cao S, Fahiminiya S, Ren H, MacDonald IM, Lopez I, Sun V, Keser V, Khan A, Stránecký V, Hartmannová H, P?istoupilová A, Hoda?ová K, ... ... Kretzschmar D, et al. Mutations in PNPLA6 are linked to photoreceptor degeneration and various forms of childhood blindness. Nature Communications. 6: 5614. PMID 25574898 DOI: 10.1038/Ncomms6614  0.443
2014 Long DM, Blake MR, Dutta S, Holbrook SD, Kotwica-Rolinska J, Kretzschmar D, Giebultowicz JM. Relationships between the circadian system and Alzheimer's disease-like symptoms in Drosophila. Plos One. 9: e106068. PMID 25171136 DOI: 10.1371/Journal.Pone.0106068  0.438
2014 Topaloglu AK, Lomniczi A, Kretzschmar D, Dissen GA, Kotan LD, McArdle CA, Koc AF, Hamel BC, Guclu M, Papatya ED, Eren E, Mengen E, Gurbuz F, Cook M, Castellano JM, et al. Loss-of-function mutations in PNPLA6 encoding neuropathy target esterase underlie pubertal failure and neurological deficits in Gordon Holmes syndrome. The Journal of Clinical Endocrinology and Metabolism. 99: E2067-75. PMID 25033069 DOI: 10.1210/Jc.2014-1836  0.316
2014 Bolkan BJ, Kretzschmar D. Loss of Tau results in defects in photoreceptor development and progressive neuronal degeneration in Drosophila. Developmental Neurobiology. 74: 1210-25. PMID 24909306 DOI: 10.1002/Dneu.22199  0.804
2014 Cook M, Bolkan BJ, Kretzschmar D. Increased actin polymerization and stabilization interferes with neuronal function and survival in the AMPKγ mutant Loechrig. Plos One. 9: e89847. PMID 24587072 DOI: 10.1371/Journal.Pone.0089847  0.803
2014 Wentzell JS, Cassar M, Kretzschmar D. Organophosphate-induced changes in the PKA regulatory function of Swiss Cheese/NTE lead to behavioral deficits and neurodegeneration. Plos One. 9: e87526. PMID 24558370 DOI: 10.1371/Journal.Pone.0087526  0.806
2013 Kruer MC, Jepperson T, Dutta S, Steiner RD, Cottenie E, Sanford L, Merkens M, Russman BS, Blasco PA, Fan G, Pollock J, Green S, Woltjer RL, Mooney C, Kretzschmar D, et al. Mutations in γ adducin are associated with inherited cerebral palsy. Annals of Neurology. 74: 805-14. PMID 23836506 DOI: 10.1002/Ana.23971  0.398
2012 Bolkan BJ, Triphan T, Kretzschmar D. β-secretase cleavage of the fly amyloid precursor protein is required for glial survival. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16181-92. PMID 23152602 DOI: 10.1523/Jneurosci.0228-12.2012  0.822
2012 Cook M, Mani P, Wentzell JS, Kretzschmar D. Increased RhoA prenylation in the loechrig (loe) mutant leads to progressive neurodegeneration. Plos One. 7: e44440. PMID 22970217 DOI: 10.1371/Journal.Pone.0044440  0.78
2012 Wentzell JS, Bolkan BJ, Carmine-Simmen K, Swanson TL, Musashe DT, Kretzschmar D. Amyloid precursor proteins are protective in Drosophila models of progressive neurodegeneration. Neurobiology of Disease. 46: 78-87. PMID 22266106 DOI: 10.1016/J.Nbd.2011.12.047  0.81
2012 Krishnan N, Rakshit K, Chow ES, Wentzell JS, Kretzschmar D, Giebultowicz JM. Loss of circadian clock accelerates aging in neurodegeneration-prone mutants. Neurobiology of Disease. 45: 1129-35. PMID 22227001 DOI: 10.1016/J.Nbd.2011.12.034  0.723
2012 Kassa R, Monterroso V, Wentzell J, Ramos AL, Couchi E, Lecomte MC, Iordanov M, Kretzschmar D, Nicolas G, Tshala-Katumbay D. Proximal giant neurofilamentous axonopathy in mice genetically engineered to resist calpain and caspase cleavage of α-II spectrin. Journal of Molecular Neuroscience : Mn. 47: 631-8. PMID 22212489 DOI: 10.1007/S12031-011-9699-8  0.688
2012 Poeck B, Strauss R, Kretzschmar D. Analysis of amyloid precursor protein function in Drosophila melanogaster. Experimental Brain Research. 217: 413-21. PMID 21912928 DOI: 10.1007/S00221-011-2860-3  0.534
2011 Eissenberg JC, Ilvarsonn AM, Sly WS, Waheed A, Krzyzanek V, Pohlmann R, Waschkau D, Kretzschmar D, Dennes AC. Drosophila GGA model: an ultimate gateway to GGA analysis. Traffic (Copenhagen, Denmark). 12: 1821-38. PMID 21923734 DOI: 10.1111/J.1600-0854.2011.01285.X  0.419
2011 Copenhaver PF, Anekonda TS, Musashe D, Robinson KM, Ramaker JM, Swanson TL, Wadsworth TL, Kretzschmar D, Woltjer RL, Quinn JF. A translational continuum of model systems for evaluating treatment strategies in Alzheimer's disease: isradipine as a candidate drug. Disease Models & Mechanisms. 4: 634-48. PMID 21596710 DOI: 10.1242/Dmm.006841  0.394
2010 Wentzell J, Kretzschmar D. Alzheimer's disease and tauopathy studies in flies and worms. Neurobiology of Disease. 40: 21-8. PMID 20302939 DOI: 10.1016/J.Nbd.2010.03.007  0.724
2010 Wang L, Ankati H, Akubathini SK, Balderamos M, Storey CA, Patel AV, Price V, Kretzschmar D, Biehl ER, D'Mello SR. Identification of novel 1,4-benzoxazine compounds that are protective in tissue culture and in vivo models of neurodegeneration. Journal of Neuroscience Research. 88: 1970-84. PMID 20143421 DOI: 10.1002/Jnr.22352  0.46
2009 Kretzschmar D. Swiss cheese et allii, some of the first neurodegenerative mutants isolated in Drosophila. Journal of Neurogenetics. 23: 34-41. PMID 19132601 DOI: 10.1080/01677060802471635  0.403
2009 Carmine-Simmen K, Proctor T, Tschäpe J, Poeck B, Triphan T, Strauss R, Kretzschmar D. Neurotoxic effects induced by the Drosophila amyloid-beta peptide suggest a conserved toxic function. Neurobiology of Disease. 33: 274-81. PMID 19049874 DOI: 10.1016/J.Nbd.2008.10.014  0.763
2008 Bettencourt da Cruz A, Wentzell J, Kretzschmar D. Swiss Cheese, a protein involved in progressive neurodegeneration, acts as a noncanonical regulatory subunit for PKA-C3. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10885-92. PMID 18945896 DOI: 10.1523/Jneurosci.3015-08.2008  0.784
2008 Hofmeyer K, Kretzschmar D, Pflugfelder GO. Optomotor-blind expression in glial cells is required for correct axonal projection across the Drosophila inner optic chiasm. Developmental Biology. 315: 28-41. PMID 18234176 DOI: 10.1016/J.Ydbio.2007.10.011  0.375
2005 Kretzschmar D. Neurodegenerative mutants in Drosophila: a means to identify genes and mechanisms involved in human diseases? Invertebrate Neuroscience : In. 5: 97-109. PMID 16187075 DOI: 10.1007/S10158-005-0005-8  0.45
2005 Mühlig-Versen M, da Cruz AB, Tschäpe JA, Moser M, Büttner R, Athenstaedt K, Glynn P, Kretzschmar D. Loss of Swiss cheese/neuropathy target esterase activity causes disruption of phosphatidylcholine homeostasis and neuronal and glial death in adult Drosophila. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2865-73. PMID 15772346 DOI: 10.1523/Jneurosci.5097-04.2005  0.819
2005 Bettencourt da Cruz A, Schwärzel M, Schulze S, Niyyati M, Heisenberg M, Kretzschmar D. Disruption of the MAP1B-related protein FUTSCH leads to changes in the neuronal cytoskeleton, axonal transport defects, and progressive neurodegeneration in Drosophila. Molecular Biology of the Cell. 16: 2433-42. PMID 15772149 DOI: 10.1091/Mbc.E04-11-1004  0.804
2005 Kretzschmar D, Tschäpe J, Bettencourt Da Cruz A, Asan E, Poeck B, Strauss R, Pflugfelder GO. Glial and neuronal expression of polyglutamine proteins induce behavioral changes and aggregate formation in Drosophila. Glia. 49: 59-72. PMID 15390099 DOI: 10.1002/Glia.20098  0.775
2004 Botella JA, Ulschmid JK, Gruenewald C, Moehle C, Kretzschmar D, Becker K, Schneuwly S. The Drosophila carbonyl reductase sniffer prevents oxidative stress-induced neurodegeneration. Current Biology : Cb. 14: 782-6. PMID 15120069 DOI: 10.1016/J.Cub.2004.04.036  0.392
2004 Greeve I, Kretzschmar D, Tschäpe JA, Beyn A, Brellinger C, Schweizer M, Nitsch RM, Reifegerste R. Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3899-906. PMID 15102905 DOI: 10.1523/Jneurosci.0283-04.2004  0.767
2004 Moser M, Li Y, Vaupel K, Kretzschmar D, Kluge R, Glynn P, Buettner R. Placental failure and impaired vasculogenesis result in embryonic lethality for neuropathy target esterase-deficient mice. Molecular and Cellular Biology. 24: 1667-79. PMID 14749382 DOI: 10.1128/Mcb.24.4.1667-1679.2004  0.446
2003 Tschäpe JA, Bettencourt da Cruz A, Kretzschmar D. Progressive neurodegeneration in Drosophila: a model system. Journal of Neural Transmission. Supplementum. 51-62. PMID 12946048 DOI: 10.1007/978-3-7091-0643-3_3  0.764
2003 Botella JA, Kretzschmar D, Kiermayer C, Feldmann P, Hughes DA, Schneuwly S. Deregulation of the Egfr/Ras signaling pathway induces age-related brain degeneration in the Drosophila mutant vap. Molecular Biology of the Cell. 14: 241-50. PMID 12529440 DOI: 10.1091/Mbc.E02-05-0297  0.441
2002 Tschäpe JA, Hammerschmied C, Mühlig-Versen M, Athenstaedt K, Daum G, Kretzschmar D. The neurodegeneration mutant löchrig interferes with cholesterol homeostasis and Appl processing. The Embo Journal. 21: 6367-76. PMID 12456644 DOI: 10.1093/Emboj/Cdf636  0.796
2002 Kretzschmar D, Pflugfelder GO. Glia in development, function, and neurodegeneration of the adult insect brain. Brain Research Bulletin. 57: 121-31. PMID 11827744 DOI: 10.1016/S0361-9230(01)00643-8  0.433
2000 Moser M, Stempfl T, Li Y, Glynn P, Büttner R, Kretzschmar D. Cloning and expression of the murine sws/NTE gene. Mechanisms of Development. 90: 279-82. PMID 10640712 DOI: 10.1016/S0925-4773(99)00239-7  0.479
1997 Kretzschmar D, Hasan G, Sharma S, Heisenberg M, Benzer S. The swiss cheese mutant causes glial hyperwrapping and brain degeneration in Drosophila. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 7425-32. PMID 9295388 DOI: 10.1523/Jneurosci.17-19-07425.1997  0.777
1995 Chang HW, Li J, Kretzschmar D, Vogt PK. Avian cellular homolog of the qin oncogene. Proceedings of the National Academy of Sciences of the United States of America. 92: 447-51. PMID 7831308 DOI: 10.1073/Pnas.92.2.447  0.318
1992 Kretzschmar D, Brunner A, Wiersdorff V, Pflugfelder GO, Heisenberg M, Schneuwly S. Giant lens, a gene involved in cell determination and axon guidance in the visual system of Drosophila melanogaster. The Embo Journal. 11: 2531-9. PMID 1628618 DOI: 10.1002/J.1460-2075.1992.Tb05318.X  0.599
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