V. Wee Yong, Ph.D. - Publications

Affiliations: 
Departments of Clinical Neurosciences and Oncology University of Calgary, Calgary, Alberta, Canada 
Area:
Multiple Sclerosis
Website:
http://www.vweeyong.com/wee_bio.htm

175 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Bhattacharya A, Kaushik DK, Lozinski BM, Yong VW. Beyond barrier functions: Roles of pericytes in homeostasis and regulation of neuroinflammation. Journal of Neuroscience Research. PMID 32815569 DOI: 10.1002/Jnr.24715  0.452
2020 Pu A, Mishra MK, Dong Y, Ghorbanigazar S, Stephenson EL, Rawji KS, Silva C, Kitagawa H, Sawcer S, Yong VW. The glycosyltransferase EXTL2 promotes proteoglycan deposition and injurious neuroinflammation following demyelination. Journal of Neuroinflammation. 17: 220. PMID 32703234 DOI: 10.1186/S12974-020-01895-1  0.461
2020 Sarkar S, Yang R, Mirzaei R, Rawji K, Poon C, Mishra MK, Zemp FJ, Bose P, Kelly J, Dunn JF, Yong VW. Control of brain tumor growth by reactivating myeloid cells with niacin. Science Translational Medicine. 12. PMID 32238578 DOI: 10.1126/Scitranslmed.Aay9924  0.338
2020 Rawji KS, Young AMH, Ghosh T, Michaels NJ, Mirzaei R, Kappen J, Kolehmainen KL, Alaeiilkhchi N, Lozinski B, Mishra MK, Pu A, Tang W, Zein S, Kaushik DK, Keough MB, ... ... Yong VW, et al. Correction to: Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system. Acta Neuropathologica. PMID 32211925 DOI: 10.1007/S00401-020-02146-6  0.752
2020 Sarkar S, Li Y, Mirzaei R, Rawji KS, Poon CC, Wang J, Kumar M, Bose P, Yong VW. Demeclocycline Reduces the Growth of Human Brain Tumor-Initiating Cells: Direct Activity and Through Monocytes. Frontiers in Immunology. 11: 272. PMID 32153581 DOI: 10.3389/Fimmu.2020.00272  0.332
2020 Rawji KS, Young AMH, Ghosh T, Michaels NJ, Mirzaei R, Kappen J, Kolehmainen KL, Alaeiilkhchi N, Lozinski B, Mishra MK, Pu A, Tang W, Zein S, Kaushik DK, Keough MB, ... ... Yong VW, et al. Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system. Acta Neuropathologica. PMID 32030468 DOI: 10.1007/S00401-020-02129-7  0.803
2020 Plemel JR, Stratton JA, Michaels NJ, Rawji KS, Zhang E, Sinha S, Baaklini CS, Dong Y, Ho M, Thorburn K, Friedman TN, Jawad S, Silva C, Caprariello AV, Hoghooghi V, ... ... Yong VW, et al. Microglia response following acute demyelination is heterogeneous and limits infiltrating macrophage dispersion. Science Advances. 6: eaay6324. PMID 31998844 DOI: 10.1126/Sciadv.Aay6324  0.791
2020 Bai Q, Xue M, Yong VW. Microglia and macrophage phenotypes in intracerebral haemorrhage injury: therapeutic opportunities. Brain : a Journal of Neurology. PMID 31919518 DOI: 10.1093/Brain/Awz393  0.391
2020 Feliu A, Mestre L, Carrillo-Salinas FJ, Yong VW, Mecha M, Guaza C. 2-arachidonoylglycerol reduces chondroitin sulphate proteoglycan production by astrocytes and enhances oligodendrocyte differentiation under inhibitory conditions. Glia. 68: 1255-1273. PMID 31894889 DOI: 10.1002/Glia.23775  0.396
2019 Dong Y, Yong VW. When encephalitogenic T cells collaborate with microglia in multiple sclerosis. Nature Reviews. Neurology. PMID 31527807 DOI: 10.1038/S41582-019-0253-6  0.418
2019 Stephenson EL, Zhang P, Ghorbani S, Wang A, Gu J, Keough MB, Rawji KS, Silva C, Yong VW, Ling CC. Targeting the Chondroitin Sulfate Proteoglycans: Evaluating Fluorinated Glucosamines and Xylosides in Screens Pertinent to Multiple Sclerosis. Acs Central Science. 5: 1223-1234. PMID 31404231 DOI: 10.1021/Acscentsci.9B00327  0.741
2019 Faissner S, Plemel JR, Gold R, Yong VW. Progressive multiple sclerosis: from pathophysiology to therapeutic strategies. Nature Reviews. Drug Discovery. PMID 31399729 DOI: 10.1038/S41573-019-0035-2  0.759
2019 Camara-Lemarroy CR, Silva C, Greenfield J, Liu WQ, Metz LM, Yong VW. Biomarkers of intestinal barrier function in multiple sclerosis are associated with disease activity. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458519863133. PMID 31317818 DOI: 10.1177/1352458519863133  0.339
2019 Hamilton AM, Forkert ND, Yang R, Wu Y, Rogers JA, Yong VW, Dunn JF. Central nervous system targeted autoimmunity causes regional atrophy: a 9.4T MRI study of the EAE mouse model of Multiple Sclerosis. Scientific Reports. 9: 8488. PMID 31186441 DOI: 10.1038/S41598-019-44682-6  0.397
2019 Koch MW, Liu WQ, Camara-Lemarroy C, Zhang Y, Pike GB, Metz L, Yong VW. Domperidone-induced elevation of serum prolactin levels and immune response in multiple sclerosis. Journal of Neuroimmunology. 334: 576974. PMID 31174092 DOI: 10.1016/J.Jneuroim.2019.576974  0.312
2019 Poon CC, Gordon PMK, Liu K, Yang R, Sarkar S, Mirzaei R, Ahmad ST, Hughes ML, Yong VW, Kelly JJP. Differential microglia and macrophage profiles in human IDH-mutant and -wild type glioblastoma. Oncotarget. 10: 3129-3143. PMID 31139325 DOI: 10.18632/Oncotarget.26863  0.318
2019 Kaushik DK, Bhattacharya A, Mirzaei R, Rawji KS, Ahn Y, Rho JM, Yong VW. Enhanced glycolytic metabolism supports transmigration of brain-infiltrating macrophages in multiple sclerosis. The Journal of Clinical Investigation. 130. PMID 31112527 DOI: 10.1172/Jci124012  0.397
2019 Yong HYF, Rawji KS, Ghorbani S, Xue M, Yong VW. The benefits of neuroinflammation for the repair of the injured central nervous system. Cellular & Molecular Immunology. 16: 540-546. PMID 30874626 DOI: 10.1038/S41423-019-0223-3  0.468
2018 Sarkar S, Poon CC, Mirzaei R, Rawji KS, Hader W, Bose P, Kelly J, Dunn JF, Yong VW. Microglia induces Gas1 expression in human brain tumor-initiating cells to reduce tumorigenecity. Scientific Reports. 8: 15286. PMID 30327548 DOI: 10.1038/S41598-018-33306-0  0.335
2018 Camara-Lemarroy CR, Metz LM, Yong VW. Focus on the gut-brain axis: Multiple sclerosis, the intestinal barrier and the microbiome. World Journal of Gastroenterology. 24: 4217-4223. PMID 30310254 DOI: 10.3748/Wjg.V24.I37.4217  0.32
2018 Mirzaei R, Sarkar S, Dzikowski L, Rawji KS, Khan L, Faissner A, Bose P, Yong VW. Brain tumor-initiating cells export tenascin-C associated with exosomes to suppress T cell activity. Oncoimmunology. 7: e1478647. PMID 30288344 DOI: 10.1080/2162402X.2018.1478647  0.318
2018 Jensen SK, Michaels NJ, Ilyntskyy S, Keough MB, Kovalchuk O, Yong VW. Multimodal Enhancement of Remyelination by Exercise with a Pivotal Role for Oligodendroglial PGC1α. Cell Reports. 24: 3167-3179. PMID 30232000 DOI: 10.1016/J.Celrep.2018.08.060  0.725
2018 Casha S, Rice T, Stirling DP, Silva C, Gnanapavan S, Giovannoni G, Hurlbert RJ, Yong VW. Cerebrospinal Fluid Biomarkers in Human Spinal Cord Injury from a Phase II Minocycline Trial. Journal of Neurotrauma. 35: 1918-1928. PMID 30074872 DOI: 10.1089/Neu.2018.5899  0.334
2018 Camara-Lemarroy CR, Metz L, Smith EE, Dunn JF, Yong VW. Expanding the Potential Therapeutic Options for Remote Ischemic Preconditioning: Use in Multiple Sclerosis. Frontiers in Neurology. 9: 475. PMID 29971043 DOI: 10.3389/Fneur.2018.00475  0.303
2018 Pu A, Stephenson EL, Yong VW. The extracellular matrix: Focus on oligodendrocyte biology and targeting CSPGs for remyelination therapies. Glia. PMID 29603376 DOI: 10.1002/Glia.23333  0.433
2018 Stephenson EL, Mishra MK, Moussienko D, Laflamme N, Rivest S, Ling CC, Yong VW. Chondroitin sulfate proteoglycans as novel drivers of leucocyte infiltration in multiple sclerosis. Brain : a Journal of Neurology. PMID 29506186 DOI: 10.1093/Brain/Awy033  0.453
2018 Rawji KS, Kappen J, Tang W, Teo W, Plemel JR, Stys PK, Yong VW. Deficient Surveillance and Phagocytic Activity of Myeloid Cells Within Demyelinated Lesions in Ageing Mice Visualized by Ex Vivo Live Multiphoton Imaging. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29363580 DOI: 10.1523/Jneurosci.2341-17.2018  0.785
2018 Poon CC, Yang R, Sheikh T, Liu K, Sarkar S, Yong VW, Kelly JJ. 59 Microglia and macrophages display heterogeneous phenotypes in IDH-mutant and -wildtype glioblastomas Canadian Journal of Neurological Sciences / Journal Canadien Des Sciences Neurologiques. 45: S15-S16. DOI: 10.1017/Cjn.2018.303  0.303
2017 Faissner S, Mishra M, Kaushik DK, Wang J, Fan Y, Silva C, Rauw G, Metz L, Koch M, Yong VW. Systematic screening of generic drugs for progressive multiple sclerosis identifies clomipramine as a promising therapeutic. Nature Communications. 8: 1990. PMID 29259169 DOI: 10.1038/S41467-017-02119-6  0.379
2017 Plemel JR, Michaels NJ, Weishaupt N, Caprariello AV, Keough MB, Rogers JA, Yukseloglu A, Lim J, Patel VV, Rawji KS, Jensen SK, Teo W, Heyne B, Whitehead SN, Stys PK, ... Yong VW, et al. Mechanisms of lysophosphatidylcholine-induced demyelination: A primary lipid disrupting myelinopathy. Glia. PMID 29068088 DOI: 10.1002/Glia.23245  0.78
2017 Faissner S, Mahjoub Y, Mishra M, Haupeltshofer S, Hahn JN, Gold R, Koch M, Metz LM, Ben-Hur T, Yong VW. Unexpected additive effects of minocycline and hydroxychloroquine in models of multiple sclerosis: Prospective combination treatment for progressive disease? Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458517728811. PMID 28857721 DOI: 10.1177/1352458517728811  0.365
2017 Plemel JR, Liu WQ, Yong VW. Remyelination therapies: a new direction and challenge in multiple sclerosis. Nature Reviews. Drug Discovery. PMID 28685761 DOI: 10.1038/Nrd.2017.115  0.742
2017 Yong HY, Yong VW. Stop inflammation and you stop neurodegeneration in MS - YES. Multiple Sclerosis (Houndmills, Basingstoke, England). 23: 1320-1321. PMID 28463075 DOI: 10.1177/1352458517707266  0.306
2017 Rogers JA, Mishra MK, Hahn J, Greene CJ, Yates RM, Metz LM, Yong VW. Gestational bisphenol-A exposure lowers the threshold for autoimmunity in a model of multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28439012 DOI: 10.1073/Pnas.1620774114  0.339
2017 Sarkar S, Mirzaei R, Zemp FJ, Wu W, Senger DL, Robbins SM, Yong VW. Activation of NOTCH signaling by tenascin-C promotes growth of human brain tumor-initiating cells. Cancer Research. PMID 28416488 DOI: 10.1158/0008-5472.Can-16-2171  0.315
2017 Poon CC, Sarkar S, Yong VW, Kelly JJ. Glioblastoma-associated microglia and macrophages: targets for therapies to improve prognosis. Brain : a Journal of Neurology. PMID 28334886 DOI: 10.1093/Brain/Aww355  0.35
2017 Plemel JR, Caprariello AV, Keough MB, Henry TJ, Tsutsui S, Chu TH, Schenk GJ, Klaver R, Yong VW, Stys PK. Unique spectral signatures of the nucleic acid dye acridine orange can distinguish cell death by apoptosis and necroptosis. The Journal of Cell Biology. PMID 28264914 DOI: 10.1083/Jcb.201602028  0.756
2017 Rice T, Larsen JE, Li H, Nuttall RK, Larsen PH, Casha S, Hurlbert J, Edwards DR, Yong VW. Neuroprotection by minocycline in murine traumatic spinal cord injury: analyses of matrix metalloproteinases Neuroimmunology and Neuroinflammation. 4: 243. DOI: 10.20517/2347-8659.2017.51  0.376
2016 Hahn JN, Kaushik DK, Mishra MK, Wang J, Silva C, Yong VW. Impact of Minocycline on Extracellular Matrix Metalloproteinase Inducer, a Factor Implicated in Multiple Sclerosis Immunopathogenesis. Journal of Immunology (Baltimore, Md. : 1950). PMID 27733550 DOI: 10.4049/Jimmunol.1600436  0.43
2016 Kaushik DK, Yong HY, Hahn JN, Silva C, Casha S, Hurlbert RJ, Jacques FH, Lisak R, Khan O, Ionete C, Larochelle C, Prat A, Bar-Or A, Yong VW. Evaluating Soluble EMMPRIN as a Marker of Disease Activity in Multiple Sclerosis: Studies of Serum and Cerebrospinal Fluid. Plos One. 11: e0163802. PMID 27727297 DOI: 10.1371/Journal.Pone.0163802  0.375
2016 Mishra MK, Yong VW. Myeloid cells - targets of medication in multiple sclerosis. Nature Reviews. Neurology. PMID 27514287 DOI: 10.1038/Nrneurol.2016.110  0.366
2016 Rawji KS, Mishra MK, Yong VW. Regenerative Capacity of Macrophages for Remyelination. Frontiers in Cell and Developmental Biology. 4: 47. PMID 27243011 DOI: 10.3389/Fcell.2016.00047  0.466
2016 Keough MB, Rogers JA, Zhang P, Jensen SK, Stephenson EL, Chen T, Hurlbert MG, Lau LW, Rawji KS, Plemel JR, Koch M, Ling CC, Yong VW. An inhibitor of chondroitin sulfate proteoglycan synthesis promotes central nervous system remyelination. Nature Communications. 7: 11312. PMID 27115988 DOI: 10.1038/Ncomms11312  0.803
2016 Shakhbazau A, Schenk GJ, Hay C, Kawasoe J, Klaver R, Yong VW, Geurts JJ, van Minnen J. Demyelination induces transport of ribosome-containing vesicles from glia to axons: evidence from animal models and MS patient brains. Molecular Biology Reports. PMID 27115494 DOI: 10.1007/S11033-016-3990-2  0.406
2016 Jensen SK, Yong VW. Activity-Dependent and Experience-Driven Myelination Provide New Directions for the Management of Multiple Sclerosis. Trends in Neurosciences. 39: 356-365. PMID 27113322 DOI: 10.1016/J.Tins.2016.04.003  0.41
2016 Rawji KS, Mishra MK, Michaels NJ, Rivest S, Stys PK, Yong VW. Immunosenescence of microglia and macrophages: impact on the ageing central nervous system. Brain : a Journal of Neurology. 139: 653-61. PMID 26912633 DOI: 10.1093/Brain/Awv395  0.632
2016 Clemente-Casares X, Blanco J, Ambalavanan P, Yamanouchi J, Singha S, Fandos C, Tsai S, Wang J, Garabatos N, Izquierdo C, Agrawal S, Keough MB, Yong VW, James E, Moore A, et al. Expanding antigen-specific regulatory networks to treat autoimmunity. Nature. PMID 26886799 DOI: 10.1038/Nature16962  0.697
2016 Zhang Y, Jonkman L, Klauser A, Barkhof F, Yong VW, Metz LM, Geurts JJ. Multi-scale MRI spectrum detects differences in myelin integrity between MS lesion types. Multiple Sclerosis (Houndmills, Basingstoke, England). PMID 26754802 DOI: 10.1177/1352458515624771  0.353
2015 Sloka S, Zhornitsky S, Silva C, Metz LM, Yong VW. 1,25-Dihydroxyvitamin D3 Protects against Immune-Mediated Killing of Neurons in Culture and in Experimental Autoimmune Encephalomyelitis. Plos One. 10: e0144084. PMID 26679341 DOI: 10.1371/Journal.Pone.0144084  0.374
2015 Shakhbazau A, Mishra M, Chu TH, Brideau C, Cummins K, Tsutsui S, Shcharbin D, Majoral JP, Mignani S, Blanchard-Desce M, Bryszewska M, Yong VW, Stys PK, van Minnen J. Fluorescent Phosphorus Dendrimer as a Spectral Nanosensor for Macrophage Polarization and Fate Tracking in Spinal Cord Injury. Macromolecular Bioscience. 15: 1523-34. PMID 26175127 DOI: 10.1002/Mabi.201500150  0.581
2015 Nathoo N, Rogers JA, Yong VW, Dunn JF. Detecting deoxyhemoglobin in spinal cord vasculature of the experimental autoimmune encephalomyelitis mouse model of multiple sclerosis using susceptibility MRI and hyperoxygenation. Plos One. 10: e0127033. PMID 25992667 DOI: 10.1371/Journal.Pone.0127033  0.327
2015 Hahn JN, Kaushik DK, Yong VW. The role of EMMPRIN in T cell biology and immunological diseases. Journal of Leukocyte Biology. 98: 33-48. PMID 25977287 DOI: 10.1189/Jlb.3Ru0215-045R  0.345
2015 Keough MB, Jensen SK, Yong VW. Experimental demyelination and remyelination of murine spinal cord by focal injection of lysolecithin. Journal of Visualized Experiments : Jove. PMID 25867716 DOI: 10.3791/52679  0.761
2015 Lampron A, Larochelle A, Laflamme N, Préfontaine P, Plante MM, Sánchez MG, Yong VW, Stys PK, Tremblay MÈ, Rivest S. Inefficient clearance of myelin debris by microglia impairs remyelinating processes. The Journal of Experimental Medicine. 212: 481-95. PMID 25779633 DOI: 10.1084/Jem.20141656  0.646
2015 Kaushik DK, Hahn JN, Yong VW. EMMPRIN, an upstream regulator of MMPs, in CNS biology. Matrix Biology : Journal of the International Society For Matrix Biology. 44: 138-146. PMID 25644103 DOI: 10.1016/J.Matbio.2015.01.018  0.37
2015 Döring A, Sloka S, Lau L, Mishra M, van Minnen J, Zhang X, Kinniburgh D, Rivest S, Yong VW. Stimulation of monocytes, macrophages, and microglia by amphotericin B and macrophage colony-stimulating factor promotes remyelination. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 1136-48. PMID 25609628 DOI: 10.1523/Jneurosci.1797-14.2015  0.439
2015 Kuhle J, Gaiottino J, Leppert D, Petzold A, Bestwick JP, Malaspina A, Lu CH, Dobson R, Disanto G, Norgren N, Nissim A, Kappos L, Hurlbert J, Yong VW, Giovannoni G, et al. Serum neurofilament light chain is a biomarker of human spinal cord injury severity and outcome. Journal of Neurology, Neurosurgery, and Psychiatry. 86: 273-9. PMID 24935984 DOI: 10.1136/Jnnp-2013-307454  0.321
2015 Bellavance MA, Gosselin D, Yong VW, Stys PK, Rivest S. Patrolling monocytes play a critical role in CX3CR1-mediated neuroprotection during excitotoxicity. Brain Structure & Function. 220: 1759-76. PMID 24706067 DOI: 10.1007/S00429-014-0759-Z  0.625
2014 Mishra MK, Wang J, Keough MB, Fan Y, Silva C, Sloka S, Hayardeny L, Brück W, Yong VW. Laquinimod reduces neuroaxonal injury through inhibiting microglial activation. Annals of Clinical and Translational Neurology. 1: 409-22. PMID 25356411 DOI: 10.1002/Acn3.67  0.763
2014 Zemp FJ, McKenzie BA, Lun X, Reilly KM, McFadden G, Yong VW, Forsyth PA. Cellular factors promoting resistance to effective treatment of glioma with oncolytic myxoma virus. Cancer Research. 74: 7260-73. PMID 25336188 DOI: 10.1158/0008-5472.Can-14-0876  0.318
2014 Ansari MK, Yong HYF, Metz L, Yong VW, Zhang Y. Changes in tissue directionality reflect differences in myelin content after demyelination in mice spinal cords Journal of Structural Biology. 188: 116-122. PMID 25281497 DOI: 10.1016/J.Jsb.2014.09.009  0.424
2014 Strachan-Whaley M, Rivest S, Yong VW. Interactions between microglia and T cells in multiple sclerosis pathobiology. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 34: 615-22. PMID 25084178 DOI: 10.1089/Jir.2014.0019  0.364
2014 Nathoo N, Yong VW, Dunn JF. Understanding disease processes in multiple sclerosis through magnetic resonance imaging studies in animal models. Neuroimage. Clinical. 4: 743-56. PMID 24936425 DOI: 10.1016/J.Nicl.2014.04.011  0.314
2014 Plemel JR, Keough MB, Duncan GJ, Sparling JS, Yong VW, Stys PK, Tetzlaff W. Remyelination after spinal cord injury: is it a target for repair? Progress in Neurobiology. 117: 54-72. PMID 24582777 DOI: 10.1016/J.Pneurobio.2014.02.006  0.785
2014 Stirling DP, Cummins K, Mishra M, Teo W, Yong VW, Stys P. Toll-like receptor 2-mediated alternative activation of microglia is protective after spinal cord injury. Brain : a Journal of Neurology. 137: 707-23. PMID 24369381 DOI: 10.1093/Brain/Awt341  0.627
2014 Sarkar S, Döring A, Zemp FJ, Silva C, Lun X, Wang X, Kelly J, Hader W, Hamilton M, Mercier P, Dunn JF, Kinniburgh D, van Rooijen N, Robbins S, Forsyth P, ... ... Yong VW, et al. Therapeutic activation of macrophages and microglia to suppress brain tumor-initiating cells. Nature Neuroscience. 17: 46-55. PMID 24316889 DOI: 10.1038/Nn.3597  0.37
2014 Nathoo N, Yong VW, Dunn JF. Using magnetic resonance imaging in animal models to guide drug development in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 20: 3-11. PMID 24263386 DOI: 10.1177/1352458513512709  0.31
2014 Zhang Y, Wells J, Buist R, Peeling J, Yong VW, Mitchell JR. Active inflammation increases the heterogeneity of MRI texture in mice with relapsing experimental allergic encephalomyelitis Magnetic Resonance Imaging. 32: 168-174. PMID 24246391 DOI: 10.1016/J.Mri.2013.10.006  0.38
2014 Christensen PC, Brideau C, Poon KW, Döring A, Yong VW, Stys PK. High-resolution fluorescence microscopy of myelin without exogenous probes. Neuroimage. 87: 42-54. PMID 24188810 DOI: 10.1016/J.Neuroimage.2013.10.050  0.589
2014 Jensen SK, Yong VW. Microglial modulation as a mechanism behind the promotion of central nervous system well-being by physical exercise Clinical and Experimental Neuroimmunology. 5: 188-201. DOI: 10.1111/Cen3.12093  0.334
2014 Mishra M, Rawji K, Keough MB, Fan Y, Yong VW. Enhancement of the activity of M2-polarized macrophages/microglia promotes recovery from demyelination Journal of Neuroimmunology. 275: 187. DOI: 10.1016/J.Jneuroim.2014.08.504  0.699
2014 Stephenson EL, Rogers JA, Keough MB, Yong VW. Changes in chondroitin sulfate proteoglycans in experimental autoimmune encephalomyelitis Journal of Neuroimmunology. 275: 175. DOI: 10.1016/J.Jneuroim.2014.08.470  0.675
2014 Hahn JN, Wang J, Silva C, Yong VW. Impact of minocycline and established MS medications on EMMPRIN, a new factor implicated in MS immunopathogenesis Journal of Neuroimmunology. 275: 152. DOI: 10.1016/J.Jneuroim.2014.08.406  0.392
2013 Lu JQ, Power C, Blevins G, Giuliani F, Yong VW. The regulation of reactive changes around multiple sclerosis lesions by phosphorylated signal transducer and activator of transcription. Journal of Neuropathology and Experimental Neurology. 72: 1135-44. PMID 24226263 DOI: 10.1097/Nen.0000000000000011  0.399
2013 Samanani S, Mishra M, Silva C, Verhaeghe B, Wang J, Tong J, Yong VW. Screening for inhibitors of microglia to reduce neuroinflammation. Cns & Neurological Disorders Drug Targets. 12: 741-9. PMID 24047520 DOI: 10.2174/18715273113126660177  0.324
2013 Lau LW, Cua R, Keough MB, Haylock-Jacobs S, Yong VW. Pathophysiology of the brain extracellular matrix: a new target for remyelination. Nature Reviews. Neuroscience. 14: 722-9. PMID 23985834 DOI: 10.1038/Nrn3550  0.738
2013 Koch MW, Cutter G, Stys PK, Yong VW, Metz LM. Treatment trials in progressive MS--current challenges and future directions. Nature Reviews. Neurology. 9: 496-503. PMID 23897406 DOI: 10.1038/Nrneurol.2013.148  0.555
2013 Sloka S, Metz LM, Hader W, Starreveld Y, Yong VW. Reduction of microglial activity in a model of multiple sclerosis by dipyridamole Journal of Neuroinflammation. 10. PMID 23866809 DOI: 10.1186/1742-2094-10-89  0.413
2013 Rawji KS, Yong VW. The benefits and detriments of macrophages/microglia in models of multiple sclerosis Clinical and Developmental Immunology. 2013. PMID 23840244 DOI: 10.1155/2013/948976  0.467
2013 Roberts DJ, Jenne CN, Léger C, Kramer AH, Gallagher CN, Todd S, Parney IF, Doig CJ, Yong VW, Kubes P, Zygun DA. Association between the cerebral inflammatory and matrix metalloproteinase responses after severe traumatic brain injury in humans. Journal of Neurotrauma. 30: 1727-36. PMID 23799281 DOI: 10.1089/Neu.2012.2842  0.321
2013 Agrawal SM, Williamson J, Sharma R, Kebir H, Patel K, Prat A, Yong VW. Extracellular matrix metalloproteinase inducer shows active perivascular cuffs in multiple sclerosis. Brain : a Journal of Neurology. 136: 1760-77. PMID 23687119 DOI: 10.1093/Brain/Awt093  0.4
2013 Cua RC, Lau LW, Keough MB, Midha R, Apte SS, Yong VW. Overcoming neurite-inhibitory chondroitin sulfate proteoglycans in the astrocyte matrix. Glia. 61: 972-84. PMID 23554135 DOI: 10.1002/Glia.22489  0.732
2013 Yong VW, Keough M, Lau L. Reply: To PMID 23034914. Annals of Neurology. 73: 316-7. PMID 23424070 DOI: 10.1002/ana.23827  0.617
2013 Keough MB, Yong VW. Remyelination therapy for multiple sclerosis. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 10: 44-54. PMID 23070731 DOI: 10.1007/S13311-012-0152-7  0.755
2013 Zhornitsky S, Yong VW, Weiss S, Metz LM. Prolactin in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 19: 15-23. PMID 22933621 DOI: 10.1177/1352458512458555  0.329
2012 Chang A, Staugaitis SM, Dutta R, Batt CE, Easley KE, Chomyk AM, Yong VW, Fox RJ, Kidd GJ, Trapp BD. Cortical remyelination: a new target for repair therapies in multiple sclerosis. Annals of Neurology. 72: 918-26. PMID 23076662 DOI: 10.1002/Ana.23693  0.397
2012 Lau LW, Keough MB, Haylock-Jacobs S, Cua R, Döring A, Sloka S, Stirling DP, Rivest S, Yong VW. Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination. Annals of Neurology. 72: 419-32. PMID 23034914 DOI: 10.1002/Ana.23599  0.764
2012 Lu JQ, Wilson BA, Yong VW, Pugh J, Mehta V. Immune cell infiltrates in atypical teratoid/rhabdoid tumors. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 39: 605-12. PMID 22931701 DOI: 10.1017/S031716710001533X  0.301
2012 Mishra MK, Wang J, Silva C, Mack M, Yong VW. Kinetics of proinflammatory monocytes in a model of multiple sclerosis and its perturbation by laquinimod. The American Journal of Pathology. 181: 642-51. PMID 22749771 DOI: 10.1016/J.Ajpath.2012.05.011  0.415
2012 Casha S, Zygun D, McGowan MD, Bains I, Yong VW, John Hurlbert R. Results of a phase II placebo-controlled randomized trial of minocycline in acute spinal cord injury Brain. 135: 1224-1236. PMID 22505632 DOI: 10.1093/Brain/Aws072  0.323
2012 Berard JL, Zarruk JG, Arbour N, Prat A, Yong VW, Jacques FH, Akira S, David S. Lipocalin 2 is a novel immune mediator of experimental autoimmune encephalomyelitis pathogenesis and is modulated in multiple sclerosis. Glia. 60: 1145-59. PMID 22499213 DOI: 10.1002/Glia.22342  0.449
2012 Agrawal SM, Silva C, Wang J, Tong JP, Yong VW. A novel anti-EMMPRIN function-blocking antibody reduces T cell proliferation and neurotoxicity: Relevance to multiple sclerosis Journal of Neuroinflammation. 9. PMID 22480370 DOI: 10.1186/1742-2094-9-64  0.366
2011 Zhang J, Sarkar S, Cua R, Zhou Y, Hader W, Yong VW. A dialog between glioma and microglia that promotes tumor invasiveness through the CCL2/CCR2/interleukin-6 axis. Carcinogenesis. 33: 312-9. PMID 22159219 DOI: 10.1093/Carcin/Bgr289  0.319
2011 Kucharova K, Chang Y, Boor A, Yong VW, Stallcup WB. Reduced inflammation accompanies diminished myelin damage and repair in the NG2 null mouse spinal cord Journal of Neuroinflammation. 8. PMID 22078261 DOI: 10.1186/1742-2094-8-158  0.362
2011 Bar-Or A, Rieckmann P, Traboulsee A, Yong VW. Targeting progressive neuroaxonal injury: Lessons from multiple sclerosis Cns Drugs. 25: 783-799. PMID 21870889 DOI: 10.2165/11587820-000000000-00000  0.398
2011 Haylock-Jacobs S, Keough MB, Lau L, Yong VW. Chondroitin sulphate proteoglycans: extracellular matrix proteins that regulate immunity of the central nervous system. Autoimmunity Reviews. 10: 766-72. PMID 21664302 DOI: 10.1016/J.Autrev.2011.05.019  0.747
2011 Doring A, Yong VW. The good, the bad and the ugly. Macrophages/microglia with a focus on myelin repair Frontiers in Bioscience - Scholar. 3: 846-856. PMID 21622236 DOI: 10.2741/191  0.346
2011 Broadwater L, Pandit A, Clements R, Azzam S, Vadnal J, Sulak M, Yong VW, Freeman EJ, Gregory RB, McDonough J. Analysis of the mitochondrial proteome in multiple sclerosis cortex. Biochimica Et Biophysica Acta. 1812: 630-41. PMID 21295140 DOI: 10.1016/J.Bbadis.2011.01.012  0.331
2011 Agrawal SM, Silva C, Tourtellotte WW, Yong VW. EMMPRIN: a novel regulator of leukocyte transmigration into the CNS in multiple sclerosis and experimental autoimmune encephalomyelitis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 669-77. PMID 21228176 DOI: 10.1523/JNEUROSCI.3659-10.2011  0.307
2011 Kwon BK, Casha S, Hurlbert RJ, Yong VW. Inflammatory and structural biomarkers in acute traumatic spinal cord injury Clinical Chemistry and Laboratory Medicine. 49: 425-433. PMID 21175377 DOI: 10.1515/Cclm.2011.068  0.327
2011 Agrawal SM, Yong VW. The many faces of EMMPRIN-Roles in neuroinflammation Biochimica Et Biophysica Acta - Molecular Basis of Disease. 1812: 213-219. PMID 20674741 DOI: 10.1016/J.Bbadis.2010.07.018  0.372
2010 Yong VW. Promoting remyelination by reducing an inhibitory microenvironment Clinical Neurology. 50: 869. PMID 21921479 DOI: 10.5692/Clinicalneurol.50.869  0.48
2010 DaSilva AG, Liaw L, Yong VW. Cleavage of osteopontin by matrix metalloproteinase-12 modulates experimental autoimmune encephalomyelitis disease in C57BL/6 mice American Journal of Pathology. 177: 1448-1458. PMID 20651245 DOI: 10.2353/Ajpath.2010.091081  0.335
2010 Lu JQ, Joseph JT, Nash RA, Storek J, Stevens AM, Metz LM, Clark AW, Johnson ES, Yong VW. Neuroinflammation and demyelination in multiple sclerosis after allogeneic hematopoietic stem cell transplantation. Archives of Neurology. 67: 716-22. PMID 20558390 DOI: 10.1001/Archneurol.2010.117  0.359
2010 Carnini A, Casha S, Yong VW, Hurlbert RJ, Braun JE. Reduction of PrP(C) in human cerebrospinal fluid after spinal cord injury. Prion. 4: 80-6. PMID 20418657 DOI: 10.4161/Pri.4.2.11756  0.317
2010 Rodrigues JC, Gonzalez GC, Zhang L, Ibrahim G, Kelly JJ, Gustafson MP, Lin Y, Dietz AB, Forsyth PA, Yong VW, Parney IF. Normal human monocytes exposed to glioma cells acquire myeloid-derived suppressor cell-like properties Neuro-Oncology. 12: 351-365. PMID 20308313 DOI: 10.1093/Neuonc/Nop023  0.352
2010 Xue M, Mikliaeva EI, Casha S, Zygun D, Demchuk A, Yong VW. Improving outcomes of neuroprotection by minocycline: Guides from cell culture and intracerebral hemorrhage in mice American Journal of Pathology. 176: 1193-1202. PMID 20110416 DOI: 10.2353/Ajpath.2010.090361  0.324
2010 Yong VW, Marks S. The interplay between the immune and central nervous systems in neuronal injury Neurology. 74: S9-S16. PMID 20038767 DOI: 10.1212/Wnl.0B013E3181C97D04  0.407
2009 Casha S, Zygun D, McGowan D, Yong VW, Hurlbert RJ. Neuroprotection with Minocycline after Spinal Cord Injury: Results of a Double Blind, Randomized, Controlled Pilot Study: 929. Neurosurgery. 65: 410-411. PMID 28173356 DOI: 10.1227/01.Neu.0000358700.03703.A5  0.305
2009 Yong VW, Rivest S. Taking advantage of the systemic immune system to cure brain diseases. Neuron. 64: 55-60. PMID 19840549 DOI: 10.1016/J.Neuron.2009.09.035  0.38
2009 Skihar V, Silva C, Chojnacki A, Döring A, Stallcup WB, Weiss S, Yong VW. Promoting oligodendrogenesis and myelin repair using the multiple sclerosis medication glatiramer acetate Proceedings of the National Academy of Sciences of the United States of America. 106: 17992-17997. PMID 19815532 DOI: 10.1073/Pnas.0909607106  0.385
2009 Ellestad KK, Tsutsui S, Noorbakhsh F, Warren KG, Yong VW, Pittman QJ, Power C. Early life exposure to lipopolysaccharide suppresses experimental autoimmune encephalomyelitis by promoting tolerogenic dendritic cells and regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 183: 298-309. PMID 19542441 DOI: 10.4049/Jimmunol.0803576  0.383
2009 Xue M, Hollenberg MD, Demchuk A, Yong VW. Relative importance of proteinase-activated receptor-1 versus matrix metalloproteinases in intracerebral hemorrhage-mediated neurotoxicity in mice. Stroke; a Journal of Cerebral Circulation. 40: 2199-204. PMID 19359644 DOI: 10.1161/Strokeaha.108.540393  0.334
2009 McCreary CR, Bjarnason TA, Skihar V, Mitchell JR, Yong VW, Dunn JF. Multiexponential T2 and magnetization transfer MRI of demyelination and remyelination in murine spinal cord Neuroimage. 45: 1173-1182. PMID 19349232 DOI: 10.1016/J.Neuroimage.2008.12.071  0.403
2009 DaSilva AG, Yong VW. Matrix metalloproteinase-12 deficiency worsens relapsing-remitting experimental autoimmune encephalomyelitis in association with cytokine and chemokine dysregulation American Journal of Pathology. 174: 898-909. PMID 19218336 DOI: 10.2353/Ajpath.2009.080952  0.351
2009 Yong VW. Prospects of repair in multiple sclerosis Journal of the Neurological Sciences. 277: S16-S18. PMID 19200859 DOI: 10.1016/S0022-510X(09)70006-1  0.408
2009 Stirling DP, Liu S, Kubes P, Yong VW. Depletion of Ly6G/Gr-1 leukocytes after spinal cord injury in mice alters wound healing and worsens neurological outcome Journal of Neuroscience. 29: 753-764. PMID 19158301 DOI: 10.1523/Jneurosci.4918-08.2009  0.381
2009 Lu JQ, Fan Y, Mitha AP, Bell R, Metz L, Moore GR, Yong VW. Association of alpha-synuclein immunoreactivity with inflammatory activity in multiple sclerosis lesions. Journal of Neuropathology and Experimental Neurology. 68: 179-89. PMID 19151622 DOI: 10.1097/Nen.0B013E318196E905  0.396
2009 Lu JQ, Storek J, Metz L, Yong VW, Stevens AM, Nash RA, Joseph JT. Continued disease activity in a patient with multiple sclerosis after allogeneic hematopoietic cell transplantation. Archives of Neurology. 66: 116-20. PMID 19139309 DOI: 10.1001/Archneurol.2008.522  0.351
2009 Xue M, Fan Y, Liu S, Zygun DA, Demchuk A, Yong VW. Contributions of multiple proteases to neurotoxicity in a mouse model of intracerebral haemorrhage Brain. 132: 26-36. PMID 18772219 DOI: 10.1093/Brain/Awn215  0.308
2008 Casha S, Yong VW, Midha R. Minocycline for axonal regeneration after nerve injury: A double-edged sword Experimental Neurology. 213: 245-248. PMID 18662690 DOI: 10.1016/J.Expneurol.2008.06.016  0.333
2008 DaSilva AG, Yong VW. Expression and regulation of matrix metalloproteinase-12 in experimental autoimmune encephalomyelitis and by bone marrow derived macrophages in vitro Journal of Neuroimmunology. 199: 24-34. PMID 18547653 DOI: 10.1016/J.Jneuroim.2008.04.034  0.334
2008 Stirling DP, Yong VW. Dynamics of the inflammatory response after murine spinal cord injury revealed by flow cytometry Journal of Neuroscience Research. 86: 1944-1958. PMID 18438914 DOI: 10.1002/Jnr.21659  0.331
2008 Agrawal SM, Lau L, Yong VW. MMPs in the central nervous system: Where the good guys go bad Seminars in Cell and Developmental Biology. 19: 42-51. PMID 17646116 DOI: 10.1016/J.Semcdb.2007.06.003  0.306
2007 Yong VW, Agrawal SM, Stirling DP. Targeting MMPs in Acute and Chronic Neurological Conditions Neurotherapeutics. 4: 580-589. PMID 17920539 DOI: 10.1016/J.Nurt.2007.07.005  0.315
2007 Schellenberg AE, Buist R, Yong VW, Del Bigio MR, Peeling J. Magnetic resonance imaging of blood-spinal cord barrier disruption in mice with experimental autoimmune encephalomyelitis. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 58: 298-305. PMID 17654586 DOI: 10.1002/Mrm.21289  0.35
2007 Agrawal SM, Yong VW. Immunopathogenesis of Multiple Sclerosis International Review of Neurobiology. 79: 99-126. PMID 17531839 DOI: 10.1016/S0074-7742(07)79005-0  0.387
2007 Yong VW, Zabad RK, Agrawal S, Goncalves DaSilva A, Metz LM. Elevation of matrix metalloproteinases (MMPs) in multiple sclerosis and impact of immunomodulators Journal of the Neurological Sciences. 259: 79-84. PMID 17382965 DOI: 10.1016/J.Jns.2006.11.021  0.333
2007 Rice T, Larsen J, Rivest S, Yong VW. Characterization of the early neuroinflammation after spinal cord injury in mice. Journal of Neuropathology and Experimental Neurology. 66: 184-95. PMID 17356380 DOI: 10.1097/01.Jnen.0000248552.07338.7F  0.378
2007 Gregg C, Shikar V, Larsen P, Mak G, Chojnacki A, Yong VW, Weiss S. White matter plasticity and enhanced remyelination in the maternal CNS Journal of Neuroscience. 27: 1812-1823. PMID 17314279 DOI: 10.1523/Jneurosci.4441-06.2007  0.408
2007 Nuttall RK, Silva C, Hader W, Bar-Or A, Patel KD, Edwards DR, Yong VW. Metalloproteinases are enriched in microglia compared with leukocytes and they regulate cytokine levels in activated microglia Glia. 55: 516-526. PMID 17216595 DOI: 10.1002/Glia.20478  0.368
2006 Xue M, Hollenberg MD, Yong VW. Combination of thrombin and matrix metalloproteinase-9 exacerbates neurotoxicity in cell culture and intracerebral hemorrhage in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10281-91. PMID 17021183 DOI: 10.1523/Jneurosci.2806-06.2006  0.345
2006 Larsen PH, DaSilva AG, Conant K, Yong VW. Myelin formation during development of the CNS is delayed in matrix metalloproteinase-9 and -12 null mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2207-14. PMID 16495447 DOI: 10.1523/Jneurosci.1880-05.2006  0.36
2005 Yong VW. Metalloproteinases: Mediators of pathology and regeneration in the CNS Nature Reviews Neuroscience. 6: 931-944. PMID 16288297 DOI: 10.1038/Nrn1807  0.429
2005 Weaver A, Goncalves da Silva A, Nuttall RK, Edwards DR, Shapiro SD, Rivest S, Yong VW. An elevated matrix metalloproteinase (MMP) in an animal model of multiple sclerosis is protective by affecting Th1/Th2 polarization. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1668-70. PMID 16081501 DOI: 10.1096/Fj.04-2030Fje  0.329
2005 Zhou Y, Zhang J, Liu Q, Bell R, Muruve DA, Forsyth P, Arcellana-Panlilio M, Robbins S, Yong VW. The chemokine GRO-α (CXCL1) confers increased tumorigenicity to glioma cells Carcinogenesis. 26: 2058-2068. PMID 16033775 DOI: 10.1093/Carcin/Bgi182  0.301
2005 Zhang J, Sarkar S, Yong VW. The chemokine stromal cell derived factor-1 (CXCL12) promotes glioma invasiveness through MT2-matrix metalloproteinase Carcinogenesis. 26: 2069-2077. PMID 16033774 DOI: 10.1093/Carcin/Bgi183  0.313
2005 Giuliani F, Hader W, Yong VW. Minocycline attenuates T cell and microglia activity to impair cytokine production in T cell-microglia interaction Journal of Leukocyte Biology. 78: 135-143. PMID 15817702 DOI: 10.1189/Jlb.0804477  0.342
2005 Wells JE, Biernaskie J, Szymanska A, Larsen PH, Yong VW, Corbett D. Matrix metalloproteinase (MMP)-12 expression has a negative impact on sensorimotor function following intracerebral haemorrhage in mice. The European Journal of Neuroscience. 21: 187-96. PMID 15654856 DOI: 10.1111/J.1460-9568.2004.03829.X  0.314
2005 Giuliani F, Metz LM, Wilson T, Fan Y, Bar-Or A, Yong VW. Additive effect of the combination of glatiramer acetate and minocycline in a model of MS. Journal of Neuroimmunology. 158: 213-21. PMID 15589056 DOI: 10.1016/J.Jneuroim.2004.09.006  0.361
2004 Yong VW, Wells J, Giuliani F, Casha S, Power C, Metz LM. The promise of minocycline in neurology Lancet Neurology. 3: 744-751. PMID 15556807 DOI: 10.1016/S1474-4422(04)00937-8  0.328
2004 Antony JM, van Marle G, Opii W, Butterfield DA, Mallet F, Yong VW, Wallace JL, Deacon RM, Warren K, Power C. Human endogenous retrovirus glycoprotein-mediated induction of redox reactants causes oligodendrocyte death and demyelination. Nature Neuroscience. 7: 1088-95. PMID 15452578 DOI: 10.1038/Nn1319  0.312
2004 Larsen PH, Yong VW. The expression of matrix metalloproteinase-12 by oligodendrocytes regulates their maturation and morphological differentiation Journal of Neuroscience. 24: 7597-7603. PMID 15342725 DOI: 10.1523/Jneurosci.2092-04.2004  0.353
2004 Metz LM, Zhang Y, Yeung M, Patry DG, Bell RB, Stoian CA, Yong VW, Patten SB, Duquette P, Antel JP, Mitchell JR. Minocycline reduces gadolinium-enhancing magnetic resonance imaging lesions in multiple sclerosis. Annals of Neurology. 55: 756. PMID 15122721 DOI: 10.1002/Ana.20111  0.311
2004 Tsutsui S, Schnermann J, Noorbakhsh F, Henry S, Yong VW, Winston BW, Warren K, Power C. A1 Adenosine Receptor Upregulation and Activation Attenuates Neuroinflammation and Demyelination in a Model of Multiple Sclerosis Journal of Neuroscience. 24: 1521-1529. PMID 14960625 DOI: 10.1523/Jneurosci.4271-03.2004  0.445
2003 Larsen PH, Wells JE, Stallcup WB, Opdenakker G, Yong VW. Matrix Metalloproteinase-9 Facilitates Remyelination in Part by Processing the Inhibitory NG2 Proteoglycan Journal of Neuroscience. 23: 11127-11135. PMID 14657171  0.301
2003 Giuliani F, Goodyer CG, Antel JP, Yong VW. Vulnerability of human neurons to T cell-mediated cytotoxicity. Journal of Immunology (Baltimore, Md. : 1950). 171: 368-79. PMID 12817020 DOI: 10.4049/Jimmunol.171.1.368  0.341
2003 Wells JEA, Hurlbert RJ, Fehlings MG, Yong VW. Neuroprotection by minocycline facilitates significant recovery from spinal cord injury in mice Brain. 126: 1628-1637. PMID 12805103 DOI: 10.1093/Brain/Awg178  0.372
2003 Le DM, Besson A, Fogg DK, Choi KS, Waisman DM, Goodyer CG, Rewcastle B, Yong VW. Exploitation of astrocytes by glioma cells to facilitate invasiveness: a mechanism involving matrix metalloproteinase-2 and the urokinase-type plasminogen activator-plasmin cascade. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 4034-43. PMID 12764090 DOI: 10.1523/Jneurosci.23-10-04034.2003  0.525
2003 Takahashi JL, Giuliani F, Power C, Imai Y, Yong VW. Interleukin-1β promotes oligodendrocyte death through glutamate excitotoxicity Annals of Neurology. 53: 588-595. PMID 12730992 DOI: 10.1002/Ana.10519  0.354
2002 Yong VW. Differential mechanisms of action of interferon-β and glatiramer acetate in MS Neurology. 59: 802-808. PMID 12349849 DOI: 10.1212/Wnl.59.6.802  0.331
2002 Brundula V, Rewcastle NB, Metz LM, Bernard CC, Yong VW. Targeting leukocyte MMPs and transmigration: minocycline as a potential therapy for multiple sclerosis. Brain : a Journal of Neurology. 125: 1297-308. PMID 12023318 DOI: 10.1093/Brain/Awf133  0.379
2002 Besson A, Wilson TL, Yong VW. The anchoring protein RACK1 links protein kinase Cepsilon to integrin beta chains. Requirements for adhesion and motility. The Journal of Biological Chemistry. 277: 22073-84. PMID 11934885 DOI: 10.1074/Jbc.M111644200  0.543
2001 Corley SM, Ladiwala U, Besson A, Yong VW. Astrocytes attenuate oligodendrocyte death in vitro through an alpha(6) integrin-laminin-dependent mechanism. Glia. 36: 281-94. PMID 11746766 DOI: 10.1002/Glia.1116  0.558
2001 Besson A, Davy A, Robbins SM, Yong VW. Differential activation of ERKs to focal adhesions by PKC epsilon is required for PMA-induced adhesion and migration of human glioma cells. Oncogene. 20: 7398-407. PMID 11704869 DOI: 10.1038/Sj.Onc.1204899  0.548
2001 Herx LM, Yong VW. Interleukin-1β is required for the early evolution of reactive astrogliosis following CNS lesion Journal of Neuropathology and Experimental Neurology. 60: 961-971. PMID 11589427 DOI: 10.1093/Jnen/60.10.961  0.354
2001 Panenka W, Jijon H, Herx LM, Armstrong JN, Feighan D, Wei T, Yong VW, Ransohoff RM, MacVicar BA. P2X7-like receptor activation in astrocytes increases chemokine monocyte chemoattractant protein-1 expression via mitogen-activated protein kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 7135-42. PMID 11549724 DOI: 10.1523/Jneurosci.21-18-07135.2001  0.329
2001 Yong VW, Power C, Forsyth P, Edwards DR. Metalloproteinases in biology and pathology of the nervous system Nature Reviews Neuroscience. 2: 502-511. PMID 11433375 DOI: 10.1038/35081571  0.313
2001 Besson A, Yong VW. Mitogenic signaling and the relationship to cell cycle regulation in astrocytomas. Journal of Neuro-Oncology. 51: 245-64. PMID 11407596 DOI: 10.1023/A:1010657030494  0.535
2001 Chabot S, Charlet D, Wilson TL, Yong VW. Cytokine production consequent to T cell--microglia interaction: the PMA/IFN gamma-treated U937 cells display similarities to human microglia. Journal of Neuroscience Methods. 105: 111-20. PMID 11275268 DOI: 10.1016/S0165-0270(00)00346-0  0.315
2000 Vecil GG, Larsen PH, Corley SM, Herx LM, Besson A, Goodyer CG, Yong VW. Interleukin-1 is a key regulator of matrix metalloproteinase-9 expression in human neurons in culture and following mouse brain trauma in vivo. Journal of Neuroscience Research. 61: 212-24. PMID 10878594 DOI: 10.1002/1097-4547(20000715)61:2<212::Aid-Jnr12>3.0.Co;2-9  0.563
2000 Besson A, Yong VW. Involvement of p21(Waf1/Cip1) in protein kinase C alpha-induced cell cycle progression. Molecular and Cellular Biology. 20: 4580-90. PMID 10848585 DOI: 10.1128/Mcb.20.13.4580-4590.2000  0.546
1999 Besson A, Robbins SM, Yong VW. PTEN/MMAC1/TEP1 in signal transduction and tumorigenesis. European Journal of Biochemistry / Febs. 263: 605-11. PMID 10469123 DOI: 10.1046/J.1432-1327.1999.00542.X  0.532
1999 Oh LYS, Larsen PH, Krekoski CA, Edwards DR, Donovan F, Werb Z, Yong VW. Matrix Metalloproteinase-9/Gelatinase B Is Required for Process Outgrowth by Oligodendrocytes The Journal of Neuroscience. 19: 8464-8475. DOI: 10.1523/Jneurosci.19-19-08464.1999  0.358
1991 Yong VW, Yong FP, Ruijs TC, Antel JP, Kim SU. Expression and modulation of HLA-DR on cultured human adult astrocytes. Journal of Neuropathology and Experimental Neurology. 50: 16-28. PMID 1898665 DOI: 10.1097/00005072-199101000-00002  0.343
1991 Yong VW, Cheung JC, Uhm JH, Kim SU. Age-dependent decrease of process formation by cultured oligodendrocytes is augmented by protein kinase C stimulation. Journal of Neuroscience Research. 29: 87-99. PMID 1886171 DOI: 10.1002/Jnr.490290110  0.337
1989 Yong VW, Horie H, Kim SU. Comparison of six different substrata on the plating efficiency, differentiation and survival of human dorsal root ganglion neurons in culture. Developmental Neuroscience. 10: 222-30. PMID 3224562 DOI: 10.1159/000111972  0.337
1989 Yong VW, Kim SU, Kim MW, Shin DH. Growth factors for human glial cells in culture. Glia. 1: 113-23. PMID 2976033 DOI: 10.1002/glia.440010203  0.347
1989 Yong VW, Guttman M, Kim SU, Calne DB, Turnbull I, Watabe K, Tomlinson RW. Transplantation of human sympathetic neurons and adrenal chromaffin cells into parkinsonian monkeys: no reversal of clinical symptoms. Journal of the Neurological Sciences. 94: 51-67. PMID 2614476 DOI: 10.1016/0022-510X(89)90217-7  0.31
1989 Kim SU, Yong VW, Watabe K, Shin DH. Human fetal Schwann cells in culture: phenotypic expressions and proliferative capability. Journal of Neuroscience Research. 22: 50-9. PMID 2538639 DOI: 10.1002/Jnr.490220107  0.346
1988 Yong VW, Sekiguchi S, Kim MW, Kim SU. Phorbol ester enhances morphological differentiation of oligodendrocytes in culture. Journal of Neuroscience Research. 19: 187-94. PMID 3367393 DOI: 10.1002/jnr.490190203  0.386
1988 Yong VW, Kim SU, Pleasure DE. Growth factors for fetal and adult human astrocytes in culture. Brain Research. 444: 59-66. PMID 3359291 DOI: 10.1016/0006-8993(88)90913-4  0.304
1987 Yong VW, Kim SU. A new double labelling immunofluorescence technique for the determination of proliferation of human astrocytes in culture. Journal of Neuroscience Methods. 21: 9-16. PMID 3309485 DOI: 10.1016/0165-0270(87)90098-7  0.306
1987 Perry TL, Yong VW, Hansen S, Jones K, Kim SU, Kurlan R, Shoulson I. Tissue culture evidence for a circulating neurotoxin in Huntington's chorea. Journal of the Neurological Sciences. 78: 139-50. PMID 2952765 DOI: 10.1016/0022-510X(87)90056-6  0.305
1987 Yong V, Watabe K, Shin D, Kim S. Studies of growth factors for human glial cells in culture Journal of Neuroimmunology. 16: 188. DOI: 10.1016/0165-5728(87)90424-3  0.314
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