Year |
Citation |
Score |
2023 |
Ishikawa Y, Bonna A, Gould DB, Farndale RW. Local Net Charge State of Collagen Triple Helix Is a Determinant of FKBP22 Binding to Collagen III. International Journal of Molecular Sciences. 24. PMID 37894834 DOI: 10.3390/ijms242015156 |
0.335 |
|
2023 |
Jooss NJ, Smith CW, Pike JA, Farndale RW, Henskens YMC, Watson SP, Heemskerk JWM, Poulter NS. Platelet GPVI cluster size is related to thrombus formation and phosphatidylserine exposure in collagen-adherent platelets under arterial shear. Journal of Thrombosis and Haemostasis : Jth. PMID 37150294 DOI: 10.1016/j.jtha.2023.04.028 |
0.322 |
|
2023 |
Jooss NJ, Henskens YMC, Watson SP, Farndale RW, Gawaz MP, Jandrot-Perrus M, Poulter NS, Heemskerk JWM. Pharmacological Inhibition of Glycoprotein VI- and Integrin α2β1-Induced Thrombus Formation Modulated by the Collagen Type. Thrombosis and Haemostasis. PMID 36807826 DOI: 10.1055/s-0043-1761463 |
0.333 |
|
2022 |
Moroi M, Induruwa I, Farndale RW, Jung SM. Factor XIII is a newly identified binding partner for platelet collagen receptor GPVI-dimer-An interaction that may modulate fibrin crosslinking. Research and Practice in Thrombosis and Haemostasis. 6: e12697. PMID 35494504 DOI: 10.1002/rth2.12697 |
0.385 |
|
2022 |
Jensen MM, Bonna A, Frederiksen SJ, Hamaia SW, Højrup P, Farndale RW, Karring H. Tyrosine-sulfated dermatopontin shares multiple binding sites and recognition determinants on triple-helical collagens with proteins implicated in cell adhesion and collagen folding, fibrillogenesis, cross-linking, and degradation. Biochimica Et Biophysica Acta. Proteins and Proteomics. 1870: 140771. PMID 35306228 DOI: 10.1016/j.bbapap.2022.140771 |
0.353 |
|
2022 |
Feitsma LJ, Brondijk HC, Jarvis GE, Hagemans D, Bihan DG, Jerah NE, Versteeg M, Farndale RW, Huizinga EG. Structural insights into collagen-binding by platelet receptor Glycoprotein VI. Blood. PMID 35245360 DOI: 10.1182/blood.2021013614 |
0.389 |
|
2021 |
Hunter EJ, Hamaia SW, Gullberg D, Malcor JD, Farndale RW. Selectivity of the collagen-binding integrin inhibitors, TC-I-15 and Obtustatin. Toxicology and Applied Pharmacology. 115669. PMID 34363821 DOI: 10.1016/j.taap.2021.115669 |
0.369 |
|
2021 |
Wright JR, Jones S, Parvathy S, Kaczmarek LK, Forsythe I, Farndale RW, Gibbins JM, Mahaut-Smith MP. The voltage-gated K channel Kv1.3 modulates platelet motility and αβ integrin-dependent adhesion to collagen. Platelets. 1-11. PMID 34348571 DOI: 10.1080/09537104.2021.1942818 |
0.336 |
|
2021 |
Moroi M, Induruwa I, Farndale RW, Jung SM. Dimers of the platelet collagen receptor Glycoprotein VI bind specifically to fibrin fibers during clot formation, but not to intact fibrinogen. Journal of Thrombosis and Haemostasis : Jth. PMID 34032355 DOI: 10.1111/jth.15399 |
0.376 |
|
2020 |
Perrella G, Huang J, Provenzale I, Swieringa F, Heubel-Moenen FCJI, Farndale RW, Roest M, van der Meijden PEJ, Thomas M, Ariëns RAS, Jandrot-Perrus M, Watson SP, Heemskerk JWM. Nonredundant Roles of Platelet Glycoprotein VI and Integrin αIIbβ3 in Fibrin-Mediated Microthrombus Formation. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314641. PMID 33267658 DOI: 10.1161/ATVBAHA.120.314641 |
0.387 |
|
2020 |
Leatherdale A, Parker D, Tasneem S, Wang Y, Bihan D, Bonna A, Hamaia SW, Gross PL, Ni H, Doble BW, Lillicrap D, Farndale RW, Hayward CPM. Multimerin 1 supports platelet function in vivo and binds to specific GPAGPOGPX motifs in fibrillar collagens that enhance platelet adhesion. Journal of Thrombosis and Haemostasis : Jth. PMID 33179420 DOI: 10.1111/jth.15171 |
0.398 |
|
2020 |
Malcor JD, Hunter EJ, Davidenko N, Bax DV, Cameron R, Best S, Sinha S, Farndale RW. Collagen scaffolds functionalized with triple-helical peptides support 3D HUVEC culture. Regenerative Biomaterials. 7: 471-482. PMID 33149936 DOI: 10.1093/Rb/Rbaa025 |
0.411 |
|
2020 |
Brouns SLN, van Geffen JP, Campello E, Swieringa F, Spiezia L, van Oerle R, Provenzale I, Verdoold R, Farndale RW, Clemetson KJ, Spronk HMH, van der Meijden PEJ, Cavill R, Kuijpers MJE, Castoldi E, et al. Platelet-primed interactions of coagulation and anticoagulation pathways in flow-dependent thrombus formation. Scientific Reports. 10: 11910. PMID 32680988 DOI: 10.1038/S41598-020-68438-9 |
0.438 |
|
2020 |
Jalan AA, Sammon D, Hartgerink JD, Brear P, Stott K, Hamaia SW, Hunter EJ, Walker DR, Leitinger B, Farndale RW. Chain alignment of collagen I deciphered using computationally designed heterotrimers. Nature Chemical Biology. PMID 31907373 DOI: 10.1038/S41589-019-0435-Y |
0.313 |
|
2020 |
Howes JM, Knäuper V, Malcor JD, Farndale RW. Cleavage by MMP-13 renders VWF unable to bind to collagen but increases its platelet-reactivity. Journal of Thrombosis and Haemostasis : Jth. PMID 31894636 DOI: 10.1111/Jth.14729 |
0.476 |
|
2019 |
Manka SW, Bihan D, Farndale RW. Structural studies of the MMP-3 interaction with triple-helical collagen introduce new roles for the enzyme in tissue remodelling. Scientific Reports. 9: 18785. PMID 31827179 DOI: 10.1038/S41598-019-55266-9 |
0.432 |
|
2019 |
Bax DV, Davidenko N, Hamaia SW, Farndale RW, Best SM, Cameron RE. Impact of UV- and carbodiimide-based crosslinking on the integrin-binding properties of collagen-based materials: Integrin binding to UV- and carbodiimide-crosslinked collagen. Acta Biomaterialia. PMID 31586463 DOI: 10.1016/J.Actbio.2019.09.046 |
0.438 |
|
2019 |
Farndale RW. Collagen-binding proteins: insights from the Collagen Toolkits. Essays in Biochemistry. 63: 337-348. PMID 31266822 DOI: 10.1042/Ebc20180070 |
0.45 |
|
2019 |
Li IC, Hulgan SAH, Walker DR, Farndale RW, Hartgerink JD, Jalan AA. Covalent Capture of a Heterotrimeric Collagen Helix. Organic Letters. PMID 31246483 DOI: 10.1021/Acs.Orglett.9B01771 |
0.313 |
|
2019 |
Jooss NJ, De Simone I, Provenzale I, Fernández DI, Brouns SLN, Farndale RW, Henskens YMC, Kuijpers MJE, Ten Cate H, van der Meijden PEJ, Cavill R, Heemskerk JWM. Role of Platelet Glycoprotein VI and Tyrosine Kinase Syk in Thrombus Formation on Collagen-Like Surfaces. International Journal of Molecular Sciences. 20. PMID 31181592 DOI: 10.3390/Ijms20112788 |
0.518 |
|
2019 |
Bax DV, Smalley HE, Farndale RW, Best SM, Cameron RE. Cellular response to collagen-elastin composite materials. Acta Biomaterialia. 86: 158-170. PMID 30586647 DOI: 10.1016/J.Actbio.2018.12.033 |
0.377 |
|
2018 |
Barrachina MN, Sueiro AM, Izquierdo I, Hermida-Nogueira L, Guitián E, Casanueva FF, Farndale RW, Moroi M, Jung SM, Pardo M, García Á. GPVI surface expression and signalling pathway activation are increased in platelets from obese patients: Elucidating potential anti-atherothrombotic targets in obesity. Atherosclerosis. 281: 62-70. PMID 30658193 DOI: 10.1016/J.Atherosclerosis.2018.12.023 |
0.301 |
|
2018 |
Chow WY, Forman CJ, Bihan D, Puszkarska AM, Rajan R, Reid DG, Slatter DA, Colwell LJ, Wales DJ, Farndale RW, Duer MJ. Proline provides site-specific flexibility for in vivo collagen. Scientific Reports. 8: 13809. PMID 30218106 DOI: 10.1038/S41598-018-31937-X |
0.748 |
|
2018 |
Malcor JD, Juskaite V, Gavriilidou D, Hunter EJ, Davidenko N, Hamaia S, Sinha S, Cameron RE, Best SM, Leitinger B, Farndale RW. Coupling of a specific photoreactive triple-helical peptide to crosslinked collagen films restores binding and activation of DDR2 and VWF. Biomaterials. 182: 21-34. PMID 30099278 DOI: 10.1016/J.Biomaterials.2018.07.050 |
0.426 |
|
2018 |
Howes JM, Pugh N, Hamaia SW, Jung SM, Knäuper V, Malcor JD, Farndale RW. MMP-13 binds to platelet receptors αIIbβ3 and GPVI and impairs aggregation and thrombus formation. Research and Practice in Thrombosis and Haemostasis. 2: 370-379. PMID 30046741 DOI: 10.1002/rth2.12088 |
0.363 |
|
2018 |
Rosini S, Pugh N, Bonna AM, Hulmes DJS, Farndale RW, Adams JC. Thrombospondin-1 promotes matrix homeostasis by interacting with collagen and lysyl oxidase precursors and collagen cross-linking sites. Science Signaling. 11. PMID 29844053 DOI: 10.1126/Scisignal.Aar2566 |
0.453 |
|
2018 |
Qiu Y, Mekkat A, Yu H, Yigit S, Hamaia S, Farndale RW, Kaplan DL, Lin YS, Brodsky B. Collagen Gly missense mutations: Effect of residue identity on collagen structure and integrin binding. Journal of Structural Biology. PMID 29758270 DOI: 10.1016/J.Jsb.2018.05.003 |
0.398 |
|
2018 |
Sasikumar P, AlOuda KS, Kaiser WJ, Holbrook LM, Kriek N, Unsworth JA, Bye AP, Sage T, Ushioda R, Nagata K, Farndale RW, Gibbins JM. The Chaperone Protein HSP47: A Platelet Collagen Binding Protein that Contributes to Thrombosis and Haemostasis. Journal of Thrombosis and Haemostasis : Jth. PMID 29512284 DOI: 10.1111/Jth.13998 |
0.408 |
|
2018 |
Misra A, Prakash P, Aggarwal H, Dhankani P, Kumar S, Pandey CP, Pugh N, Bihan D, Barthwal MK, Farndale RW, Dikshit DK, Dikshit M. Anti-thrombotic efficacy of S007-867: pre-clinical evaluation in experimental models of thrombosis in vivo and in vitro. Biochemical Pharmacology. PMID 29309758 DOI: 10.1016/J.Bcp.2018.01.013 |
0.422 |
|
2018 |
Davidenko N, Hamaia S, Bax DV, Malcor JD, Schuster CF, Gullberg D, Farndale RW, Best SM, Cameron RE. Selecting the correct cellular model for assessing of the biological response of collagen-based biomaterials. Acta Biomaterialia. 65: 88-101. PMID 29107054 DOI: 10.1016/J.Actbio.2017.10.035 |
0.415 |
|
2017 |
Induruwa I, Moroi M, Bonna A, Malcor JD, Howes JM, Warburton EA, Farndale RW, Jung SM. Platelet collagen receptor GPVI-dimer recognizes fibrinogen and fibrin through their D-domains, contributing to platelet adhesion and activation during thrombus formation. Journal of Thrombosis and Haemostasis : Jth. PMID 29210180 DOI: 10.1111/Jth.13919 |
0.512 |
|
2017 |
Pugh N, Maddox BD, Bihan D, Taylor KA, Mahaut-Smith MP, Farndale RW. Differential integrin activity mediated by platelet collagen receptor engagement under flow conditions. Thrombosis and Haemostasis. PMID 28536721 DOI: 10.1160/Th16-12-0906 |
0.434 |
|
2017 |
Paracuellos P, Kalamajski S, Bonna A, Bihan D, Farndale RW, Hohenester E. Structural and functional analysis of two small leucine-rich repeat proteoglycans, fibromodulin and chondroadherin. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 28215822 DOI: 10.1016/J.Matbio.2017.02.002 |
0.457 |
|
2017 |
Poulter NS, Pollitt AY, Owen DM, Gardiner EE, Andrews RK, Shimizu H, Ishikawa D, Bihan D, Farndale RW, Moroi M, Watson SP, Jung SM. Clustering of GPVI dimers upon adhesion to collagen as a mechanism to regulate GPVI signalling in platelets. Journal of Thrombosis and Haemostasis : Jth. PMID 28058806 DOI: 10.1111/Jth.13613 |
0.473 |
|
2017 |
Bax DV, Davidenko N, Gullberg D, Hamaia SW, Farndale RW, Best SM, Cameron RE. Fundamental insight into the effect of carbodiimide crosslinking on cellular recognition of collagen-based scaffolds. Acta Biomaterialia. 49: 218-234. PMID 27915017 DOI: 10.1016/J.Actbio.2016.11.059 |
0.412 |
|
2016 |
Davidenko N, Schuster CF, Bax DV, Farndale RW, Hamaia S, Best SM, Cameron RE. Evaluation of cell binding to collagen and gelatin: a study of the effect of 2D and 3D architecture and surface chemistry. Journal of Materials Science. Materials in Medicine. 27: 148. PMID 27582068 DOI: 10.1007/S10856-016-5763-9 |
0.421 |
|
2016 |
Hamaia SW, Luff D, Hunter EJ, Malcor JD, Bihan D, Gullberg D, Farndale RW. Unique charge-dependent constraint on collagen recognition by integrin α10β1. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 27569273 DOI: 10.1016/J.Matbio.2016.08.010 |
0.435 |
|
2016 |
Yigit S, Yu H, An B, Hamaia S, Farndale RW, Kaplan DL, Lin YS, Brodsky B. Mapping the Effect of Gly Mutations in Collagen on α2β1 Integrin Binding. The Journal of Biological Chemistry. PMID 27432884 DOI: 10.1074/Jbc.M116.726182 |
0.406 |
|
2016 |
Nunes AM, Zhu J, Jezioro J, Minetti CA, Remeta DP, Farndale RW, Hamaia SW, Baum J. Intrinsic local destabilization of the C-terminus predisposes integrin α1 I domain to a conformational switch induced by collagen binding. Protein Science : a Publication of the Protein Society. PMID 27342747 DOI: 10.1002/Pro.2972 |
0.407 |
|
2016 |
Parker DN, Tasneem S, Farndale RW, Bihan D, Sadler JE, Sebastian S, De Groot PG, Hayward CP. The functions of the A1A2A3 domains in von Willebrand factor include multimerin 1 binding. Thrombosis and Haemostasis. 116. PMID 27052467 DOI: 10.1160/Th15-09-0700 |
0.459 |
|
2016 |
Kalamajski S, Bihan D, Bonna A, Rubin K, Farndale RW. Fibromodulin Interacts with Collagen Cross-linking Sites and Activates Lysyl Oxidase. The Journal of Biological Chemistry. 291: 7951-60. PMID 26893379 DOI: 10.1074/Jbc.M115.693408 |
0.424 |
|
2016 |
Malcor JD, Bax D, Hamaia SW, Davidenko N, Best SM, Cameron RE, Farndale RW, Bihan D. The synthesis and coupling of photoreactive collagen-based peptides to restore integrin reactivity to an inert substrate, chemically-crosslinked collagen. Biomaterials. 85: 65-77. PMID 26854392 DOI: 10.1016/J.Biomaterials.2016.01.044 |
0.445 |
|
2016 |
Davidenko N, Bax DV, Schuster CF, Farndale RW, Hamaia SW, Best SM, Cameron RE. Optimisation of UV irradiation as a binding site conserving method for crosslinking collagen-based scaffolds. Journal of Materials Science. Materials in Medicine. 27: 14. PMID 26676860 DOI: 10.1007/S10856-015-5627-8 |
0.353 |
|
2016 |
Slatter DA, Farndale RW. Structural constraints on the evolution of the collagen fibril: convergence on a 1014-residue COL domain. Open Biology. 5. PMID 25994354 DOI: 10.1098/Rsob.140220 |
0.379 |
|
2015 |
An B, Abbonante V, Xu H, Gavriilidou D, Yoshizumi A, Bihan D, Farndale RW, Kaplan DL, Balduini A, Leitinger B, Brodsky B. Recombinant Collagen Engineered to Bind to Discoidin Domain Receptors Functions as a Receptor Inhibitor. The Journal of Biological Chemistry. PMID 26702058 DOI: 10.1074/Jbc.M115.674507 |
0.501 |
|
2015 |
Zhou L, Hinerman JM, Blaszczyk M, Miller JL, Conrady DG, Barrow AD, Chirgadze DY, Bihan D, Farndale RW, Herr AB. Structural basis for collagen recognition by the immune receptor OSCAR. Blood. PMID 26552697 DOI: 10.1182/Blood-2015-08-667055 |
0.407 |
|
2015 |
Howes JM, Pugh N, Knäuper V, Farndale RW. Modified platelet deposition on matrix metalloproteinase 13 digested collagen I. Journal of Thrombosis and Haemostasis : Jth. 13: 2253-9. PMID 26447617 DOI: 10.1111/Jth.13166 |
0.412 |
|
2015 |
Watson BR, White NA, Taylor KA, Howes JM, Malcor JM, Bihan D, Sage SO, Farndale RW, Pugh N. Zinc is a transmembrane agonist that induces platelet activation in a tyrosine phosphorylation-dependent manner. Metallomics : Integrated Biometal Science. PMID 26434726 DOI: 10.1039/C5Mt00064E |
0.467 |
|
2015 |
Ying Chow W, Bihan D, Forman CJ, Slatter DA, Reid DG, Wales DJ, Farndale RW, Duer MJ. Hydroxyproline Ring Pucker Causes Frustration of Helix Parameters in the Collagen Triple Helix. Scientific Reports. 5: 12556. PMID 26220399 DOI: 10.1038/Srep12556 |
0.619 |
|
2015 |
Davidenko N, Schuster CF, Bax DV, Raynal N, Farndale RW, Best SM, Cameron RE. Control of crosslinking for tailoring collagen-based scaffolds stability and mechanics. Acta Biomaterialia. 25: 131-42. PMID 26213371 DOI: 10.1016/J.Actbio.2015.07.034 |
0.389 |
|
2015 |
Jamasbi J, Megens RT, Bianchini M, Münch G, Ungerer M, Faussner A, Sherman S, Walker A, Goyal P, Jung S, Brandl R, Weber C, Lorenz R, Farndale R, Elia N, et al. Differential Inhibition of Human Atherosclerotic Plaque-Induced Platelet Activation by Dimeric GPVI-Fc and Anti-GPVI Antibodies: Functional and Imaging Studies. Journal of the American College of Cardiology. 65: 2404-15. PMID 26046734 DOI: 10.1016/J.Jacc.2015.03.573 |
0.424 |
|
2015 |
Pugh N, Bihan D, Perry DJ, Farndale RW. Dynamic analysis of platelet deposition to resolve platelet adhesion receptor activity in whole blood at arterial shear rate. Platelets. 26: 216-9. PMID 24679363 DOI: 10.3109/09537104.2014.893289 |
0.331 |
|
2014 |
de Witt SM, Swieringa F, Cavill R, Lamers MM, van Kruchten R, Mastenbroek T, Baaten C, Coort S, Pugh N, Schulz A, Scharrer I, Jurk K, Zieger B, Clemetson KJ, Farndale RW, et al. Identification of platelet function defects by multi-parameter assessment of thrombus formation. Nature Communications. 5: 4257. PMID 25027852 DOI: 10.1038/ncomms5257 |
0.319 |
|
2014 |
Hamaia S, Farndale RW. Integrin recognition motifs in the human collagens. Advances in Experimental Medicine and Biology. 819: 127-42. PMID 25023172 DOI: 10.1007/978-94-017-9153-3_9 |
0.328 |
|
2014 |
Howes JM, Bihan D, Slatter DA, Hamaia SW, Packman LC, Knauper V, Visse R, Farndale RW. The recognition of collagen and triple-helical toolkit peptides by MMP-13: sequence specificity for binding and cleavage. The Journal of Biological Chemistry. 289: 24091-101. PMID 25008319 DOI: 10.1074/jbc.M114.583443 |
0.313 |
|
2014 |
Chow WY, Rajan R, Muller KH, Reid DG, Skepper JN, Wong WC, Brooks RA, Green M, Bihan D, Farndale RW, Slatter DA, Shanahan CM, Duer MJ. NMR spectroscopy of native and in vitro tissues implicates polyADP ribose in biomineralization. Science (New York, N.Y.). 344: 742-6. PMID 24833391 DOI: 10.1126/science.1248167 |
0.669 |
|
2014 |
Tersteeg C, Heijnen HF, Eckly A, Pasterkamp G, Urbanus RT, Maas C, Hoefer IE, Nieuwland R, Farndale RW, Gachet C, de Groot PG, Roest M. FLow-induced PRotrusions (FLIPRs): a platelet-derived platform for the retrieval of microparticles by monocytes and neutrophils. Circulation Research. 114: 780-91. PMID 24406984 DOI: 10.1161/Circresaha.114.302361 |
0.383 |
|
2013 |
Sage SO, Pugh N, Farndale RW, Harper AG. Pericellular Ca(2+) recycling potentiates thrombin-evoked Ca(2+) signals in human platelets. Physiological Reports. 1: e00085. PMID 24303163 DOI: 10.1002/Phy2.85 |
0.339 |
|
2013 |
Bleijerveld OB, van Holten TC, Preisinger C, van der Smagt JJ, Farndale RW, Kleefstra T, Willemsen MH, Urbanus RT, de Groot PG, Heck AJ, Roest M, Scholten A. Targeted phosphotyrosine profiling of glycoprotein VI signaling implicates oligophrenin-1 in platelet filopodia formation. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 1538-43. PMID 23619296 DOI: 10.1161/Atvbaha.112.300916 |
0.382 |
|
2013 |
Attwood SJ, Simpson AM, Hamaia SW, Bihan D, Roy D, Farndale RW, Welland ME. Measurement of the Interaction Between Recombinant I-domain from Integrin alpha 2 beta 1 and a Triple Helical Collagen Peptide with the GFOGER Binding Motif Using Molecular Force Spectroscopy. International Journal of Molecular Sciences. 14: 2832-45. PMID 23434650 DOI: 10.3390/Ijms14022832 |
0.44 |
|
2013 |
Cloutier N, Tan S, Boudreau LH, Cramb C, Subbaiah R, Lahey L, Albert A, Shnayder R, Gobezie R, Nigrovic PA, Farndale RW, Robinson WH, Brisson A, Lee DM, Boilard E. The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexes. Embo Molecular Medicine. 5: 235-49. PMID 23165896 DOI: 10.1002/Emmm.201201846 |
0.305 |
|
2012 |
Freise C, Ruehl M, Erben U, Farndale RW, Somasundaram R, Heimesaat MM. The synthetic hydroxyproline-containing collagen analogue (Gly-Pro-Hyp)10 promotes enzymatic activity of matrixmetalloproteinase-2 in vitro. European Journal of Microbiology & Immunology. 2: 186-91. PMID 24688764 DOI: 10.1556/Eujmi.2.2012.3.3 |
0.386 |
|
2012 |
Xu H, Bihan D, Chang F, Huang PH, Farndale RW, Leitinger B. Discoidin domain receptors promote α1β1- and α2β1-integrin mediated cell adhesion to collagen by enhancing integrin activation. Plos One. 7: e52209. PMID 23284937 DOI: 10.1371/Journal.Pone.0052209 |
0.472 |
|
2012 |
Jung SM, Moroi M, Soejima K, Nakagaki T, Miura Y, Berndt MC, Gardiner EE, Howes JM, Pugh N, Bihan D, Watson SP, Farndale RW. Constitutive dimerization of glycoprotein VI (GPVI) in resting platelets is essential for binding to collagen and activation in flowing blood. The Journal of Biological Chemistry. 287: 30000-13. PMID 22773837 DOI: 10.1074/Jbc.M112.359125 |
0.521 |
|
2012 |
Manka SW, Carafoli F, Visse R, Bihan D, Raynal N, Farndale RW, Murphy G, Enghild JJ, Hohenester E, Nagase H. Structural insights into triple-helical collagen cleavage by matrix metalloproteinase 1. Proceedings of the National Academy of Sciences of the United States of America. 109: 12461-6. PMID 22761315 DOI: 10.1073/Pnas.1204991109 |
0.418 |
|
2012 |
Almquist T, Jacobson SH, Lins PE, Farndale RW, Hjemdahl P. Effects of lipid-lowering treatment on platelet reactivity and platelet-leukocyte aggregation in diabetic patients without and with chronic kidney disease: a randomized trial. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 27: 3540-6. PMID 22700717 DOI: 10.1093/Ndt/Gfs183 |
0.361 |
|
2012 |
Hamaia SW, Pugh N, Raynal N, Némoz B, Stone R, Gullberg D, Bihan D, Farndale RW. Mapping of potent and specific binding motifs, GLOGEN and GVOGEA, for integrin α1β1 using collagen toolkits II and III. The Journal of Biological Chemistry. 287: 26019-28. PMID 22654115 DOI: 10.1074/Jbc.M112.353144 |
0.417 |
|
2012 |
Slatter DA, Bihan DG, Jarvis GE, Stone R, Pugh N, Giddu S, Farndale RW. The properties conferred upon triple-helical collagen-mimetic peptides by the presence of cysteine residues. Peptides. 36: 86-93. PMID 22555281 DOI: 10.1016/J.Peptides.2012.04.013 |
0.423 |
|
2012 |
Cloutier N, Paré A, Farndale RW, Schumacher HR, Nigrovic PA, Lacroix S, Boilard E. Platelets can enhance vascular permeability. Blood. 120: 1334-43. PMID 22544703 DOI: 10.1182/Blood-2012-02-413047 |
0.402 |
|
2012 |
Grover CN, Farndale RW, Best SM, Cameron RE. The interplay between physical and chemical properties of protein films affects their bioactivity. Journal of Biomedical Materials Research. Part A. 100: 2401-11. PMID 22528690 DOI: 10.1002/Jbm.A.34187 |
0.307 |
|
2012 |
Brondijk TH, Bihan D, Farndale RW, Huizinga EG. Implications for collagen I chain registry from the structure of the collagen von Willebrand factor A3 domain complex. Proceedings of the National Academy of Sciences of the United States of America. 109: 5253-8. PMID 22440751 DOI: 10.1073/Pnas.1112388109 |
0.468 |
|
2012 |
Kunicki TJ, Williams SA, Diaz D, Farndale RW, Nugent DJ. Platelet adhesion to decorin but not collagen I correlates with the integrin α2 dimorphism E534K, the basis of the human platelet alloantigen (HPA)-5 system. Haematologica. 97: 692-5. PMID 22133774 DOI: 10.3324/Haematol.2011.056556 |
0.462 |
|
2012 |
Pugh N, Jarvis GE, Koch A, Sakariassen KS, Davis B, Farndale RW. The impact of factor Xa inhibition on axial dependent arterial thrombus formation triggered by a tissue factor rich surface. Journal of Thrombosis and Thrombolysis. 33: 6-15. PMID 22120925 DOI: 10.1007/S11239-011-0658-6 |
0.302 |
|
2012 |
Jarvis GE, Bihan D, Hamaia S, Pugh N, Ghevaert CJ, Pearce AC, Hughes CE, Watson SP, Ware J, Rudd CE, Farndale RW. A role for adhesion and degranulation-promoting adapter protein in collagen-induced platelet activation mediated via integrin α(2) β(1). Journal of Thrombosis and Haemostasis : Jth. 10: 268-77. PMID 22103309 DOI: 10.1111/J.1538-7836.2011.04567.X |
0.417 |
|
2012 |
Pugh N, Perry D, Farndale R. Assessment of synthetic collagen-mimetic peptides and novel image analysis techniques in the diagnosis of platelet-related bleeding disorders Atherosclerosis. 225: e5. DOI: 10.1016/J.Atherosclerosis.2012.10.018 |
0.368 |
|
2011 |
Vadon-Le Goff S, Kronenberg D, Bourhis JM, Bijakowski C, Raynal N, Ruggiero F, Farndale RW, Stöcker W, Hulmes DJ, Moali C. Procollagen C-proteinase enhancer stimulates procollagen processing by binding to the C-propeptide region only. The Journal of Biological Chemistry. 286: 38932-8. PMID 21940633 DOI: 10.1074/Jbc.M111.274944 |
0.365 |
|
2011 |
Slatter DA, Bihan DG, Farndale RW. The effect of purity upon the triple-helical stability of collagenous peptides. Biomaterials. 32: 6621-32. PMID 21663955 DOI: 10.1016/J.Biomaterials.2011.05.025 |
0.348 |
|
2011 |
Heemskerk JW, Sakariassen KS, Zwaginga JJ, Brass LF, Jackson SP, Farndale RW. Collagen surfaces to measure thrombus formation under flow: possibilities for standardization. Journal of Thrombosis and Haemostasis : Jth. 9: 856-8. PMID 21595091 DOI: 10.1111/J.1538-7836.2011.04230.X |
0.321 |
|
2011 |
Boilard E, Larabee K, Shnayder R, Jacobs K, Farndale RW, Ware J, Lee DM. Platelets participate in synovitis via Cox-1-dependent synthesis of prostacyclin independently of microparticle generation. Journal of Immunology (Baltimore, Md. : 1950). 186: 4361-6. PMID 21357261 DOI: 10.4049/Jimmunol.1002857 |
0.406 |
|
2011 |
Castillo-Briceño P, Bihan D, Nilges M, Hamaia S, Meseguer J, García-Ayala A, Farndale RW, Mulero V. A role for specific collagen motifs during wound healing and inflammatory response of fibroblasts in the teleost fish gilthead seabream. Molecular Immunology. 48: 826-34. PMID 21232799 DOI: 10.1016/J.Molimm.2010.12.004 |
0.443 |
|
2011 |
Ruehl M, Muche M, Freise C, Erben U, Neumann U, Schuppan D, Popov Y, Dieterich W, Zeitz M, Farndale RW, Somasundaram R. Hydroxyproline-containing collagen analogs trigger the release and activation of collagen-sequestered proMMP-2 by competition with prodomain-derived peptide P33-42. Fibrogenesis & Tissue Repair. 4: 1. PMID 21211003 DOI: 10.1186/1755-1536-4-1 |
0.4 |
|
2011 |
Xu H, Raynal N, Stathopoulos S, Myllyharju J, Farndale RW, Leitinger B. Collagen binding specificity of the discoidin domain receptors: binding sites on collagens II and III and molecular determinants for collagen IV recognition by DDR1. Matrix Biology : Journal of the International Society For Matrix Biology. 30: 16-26. PMID 21044884 DOI: 10.1016/J.Matbio.2010.10.004 |
0.484 |
|
2011 |
Cloutier N, Farndale RW, Brisson A, Boilard E. Functions of Platelet Microparticles in Inflammatory Arthritis Blood. 118: SCI-35-SCI-35. DOI: 10.1182/Blood.V118.21.Sci-35.Sci-35 |
0.38 |
|
2011 |
Kunicki TJ, Diaz D, Williams SA, Farndale RW, Nugent DJ. The Integrin α2 Dimorphism E534K Modulates Platelet Binding to Decorin but Not Collagen I, Blood. 118: 3256-3256. DOI: 10.1182/Blood.V118.21.3256.3256 |
0.476 |
|
2011 |
Tasneem S, Pawlikowska M, Bihan D, Farndale RW, Hayward CPM. Interaction of Multimerin 1 with Collagens: Role in Platelet Adhesion Blood. 118: 2207-2207. DOI: 10.1182/Blood.V118.21.2207.2207 |
0.53 |
|
2010 |
van Wieringen T, Kalamajski S, Lidén A, Bihan D, Guss B, Heinegård D, Farndale RW, Rubin K. The streptococcal collagen-binding protein CNE specifically interferes with alphaVbeta3-mediated cellular interactions with triple helical collagen. The Journal of Biological Chemistry. 285: 35803-13. PMID 20837478 DOI: 10.1074/Jbc.M110.146001 |
0.462 |
|
2010 |
Erat MC, Schwarz-Linek U, Pickford AR, Farndale RW, Campbell ID, Vakonakis I. Implications for collagen binding from the crystallographic structure of fibronectin 6FnI1-2FnII7FnI Journal of Biological Chemistry. 285: 33764-33770. PMID 20739283 DOI: 10.1074/Jbc.M110.139394 |
0.464 |
|
2010 |
Leo JC, Elovaara H, Bihan D, Pugh N, Kilpinen SK, Raynal N, Skurnik M, Farndale RW, Goldman A. First analysis of a bacterial collagen-binding protein with collagen Toolkits: promiscuous binding of YadA to collagens may explain how YadA interferes with host processes. Infection and Immunity. 78: 3226-36. PMID 20439473 DOI: 10.1128/Iai.01057-09 |
0.465 |
|
2010 |
Pugh N, Simpson AM, Smethurst PA, de Groot PG, Raynal N, Farndale RW. Synergism between platelet collagen receptors defined using receptor-specific collagen-mimetic peptide substrata in flowing blood. Blood. 115: 5069-79. PMID 20351310 DOI: 10.1182/blood-2010-01-260778 |
0.408 |
|
2010 |
Brondijk TH, de Ruiter T, Ballering J, Wienk H, Lebbink RJ, van Ingen H, Boelens R, Farndale RW, Meyaard L, Huizinga EG. Crystal structure and collagen-binding site of immune inhibitory receptor LAIR-1: unexpected implications for collagen binding by platelet receptor GPVI. Blood. 115: 1364-73. PMID 20007810 DOI: 10.1182/Blood-2009-10-246322 |
0.473 |
|
2009 |
Carafoli F, Bihan D, Stathopoulos S, Konitsiotis AD, Kvansakul M, Farndale RW, Leitinger B, Hohenester E. Crystallographic insight into collagen recognition by discoidin domain receptor 2. Structure (London, England : 1993). 17: 1573-1581. PMID 20004161 DOI: 10.1016/J.Str.2009.10.012 |
0.458 |
|
2009 |
Freise C, Erben U, Muche M, Farndale R, Zeitz M, Somasundaram R, Ruehl M. The alpha 2 chain of collagen type VI sequesters latent proforms of matrix-metalloproteinases and modulates their activation and activity. Matrix Biology : Journal of the International Society For Matrix Biology. 28: 480-9. PMID 19698785 DOI: 10.1016/J.Matbio.2009.08.001 |
0.381 |
|
2009 |
Farndale RW. Platelet glycoprotein VI as a mediator of metastasis. Journal of Thrombosis and Haemostasis : Jth. 7: 1711-2. PMID 19682240 DOI: 10.1111/J.1538-7836.2009.03566.X |
0.414 |
|
2009 |
Walker A, Pugh N, Garner SF, Stephens J, Maddox B, Ouwehand WH, Farndale RW, Steward M. Single domain antibodies against the collagen signalling receptor glycoprotein VI are inhibitors of collagen induced thrombus formation. Platelets. 20: 268-76. PMID 19459133 DOI: 10.1080/09537100902893792 |
0.503 |
|
2009 |
Jones CI, Bray S, Garner SF, Stephens J, de Bono B, Angenent WG, Bentley D, Burns P, Coffey A, Deloukas P, Earthrowl M, Farndale RW, Hoylaerts MF, Koch K, Rankin A, et al. A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways. Blood. 114: 1405-16. PMID 19429868 DOI: 10.1182/Blood-2009-02-202614 |
0.371 |
|
2009 |
Herr AB, Farndale RW. Structural insights into the interactions between platelet receptors and fibrillar collagen Journal of Biological Chemistry. 284: 19781-19785. PMID 19401461 DOI: 10.1074/Jbc.R109.013219 |
0.484 |
|
2009 |
Lebbink RJ, Raynal N, de Ruiter T, Bihan DG, Farndale RW, Meyaard L. Identification of multiple potent binding sites for human leukocyte associated Ig-like receptor LAIR on collagens II and III. Matrix Biology : Journal of the International Society For Matrix Biology. 28: 202-10. PMID 19345263 DOI: 10.1016/J.Matbio.2009.03.005 |
0.463 |
|
2009 |
Erat MC, Slatter DA, Lowe ED, Millard CJ, Farndale RW, Campbell ID, Vakonakis I. Identification and structural analysis of type i collagen sites in complex with fibronectin fragments Proceedings of the National Academy of Sciences of the United States of America. 106: 4195-4200. PMID 19251642 DOI: 10.1073/Pnas.0812516106 |
0.46 |
|
2008 |
Hohenester E, Sasaki T, Giudici C, Farndale RW, Bächinger HP. Structural basis of sequence-specific collagen recognition by SPARC. Proceedings of the National Academy of Sciences of the United States of America. 105: 18273-7. PMID 19011090 DOI: 10.1073/Pnas.0808452105 |
0.514 |
|
2008 |
Roberts W, Riba R, Homer-Vanniasinkam S, Farndale RW, Naseem KM. Nitric oxide specifically inhibits integrin-mediated platelet adhesion and spreading on collagen. Journal of Thrombosis and Haemostasis : Jth. 6: 2175-85. PMID 18983487 DOI: 10.1111/J.1538-7836.2008.03190.X |
0.412 |
|
2008 |
Munnix IC, Gilio K, Siljander PR, Raynal N, Feijge MA, Hackeng TM, Deckmyn H, Smethurst PA, Farndale RW, Heemskerk JW. Collagen-mimetic peptides mediate flow-dependent thrombus formation by high- or low-affinity binding of integrin alpha2beta1 and glycoprotein VI. Journal of Thrombosis and Haemostasis : Jth. 6: 2132-42. PMID 18826391 DOI: 10.1111/j.1538-7836.2008.03167.x |
0.417 |
|
2008 |
Gigout A, Jolicoeur M, Nelea M, Raynal N, Farndale R, Buschmann MD. Chondrocyte aggregation in suspension culture is GFOGER-GPP- and beta1 integrin-dependent. The Journal of Biological Chemistry. 283: 31522-30. PMID 18723503 DOI: 10.1074/Jbc.M804234200 |
0.441 |
|
2008 |
Giudici C, Raynal N, Wiedemann H, Cabral WA, Marini JC, Timpl R, Bächinger HP, Farndale RW, Sasaki T, Tenni R. Mapping of SPARC/BM-40/osteonectin-binding sites on fibrillar collagens. The Journal of Biological Chemistry. 283: 19551-60. PMID 18487610 DOI: 10.1074/Jbc.M710001200 |
0.461 |
|
2008 |
Farndale RW, Lisman T, Bihan D, Hamaia S, Smerling CS, Pugh N, Konitsiotis A, Leitinger B, de Groot PG, Jarvis GE, Raynal N. Cell-collagen interactions: the use of peptide Toolkits to investigate collagen-receptor interactions. Biochemical Society Transactions. 36: 241-50. PMID 18363567 DOI: 10.1042/BST0360241 |
0.393 |
|
2008 |
Jarvis GE, Raynal N, Langford JP, Onley DJ, Andrews A, Smethurst PA, Farndale RW. Identification of a major GpVI-binding locus in human type III collagen. Blood. 111: 4986-96. PMID 18305222 DOI: 10.1182/Blood-2007-08-108472 |
0.413 |
|
2008 |
Konitsiotis AD, Raynal N, Bihan D, Hohenester E, Farndale RW, Leitinger B. Characterization of high affinity binding motifs for the discoidin domain receptor DDR2 in collagen. The Journal of Biological Chemistry. 283: 6861-8. PMID 18201965 DOI: 10.1074/Jbc.M709290200 |
0.465 |
|
2008 |
Freise C, Ruehl M, Erben U, Seja M, Farndale R, Zeitz M, Somasundaram R. 472 THE TRIPLEHELICAL PEPTIDE (GPO)10 INTERACTS WITH THE CBD OF MMP-2 RESULTING IN A DIMINISHED BINDING OF MMP-2 TO FIBRILLAR LIVER COLLAGENS AND ENHANCED MATRIX DEGRADATION Journal of Hepatology. 48: S179-S180. DOI: 10.1016/S0168-8278(08)60474-2 |
0.369 |
|
2007 |
Jones CI, Garner SF, Angenent W, Bernard A, Berzuini C, Burns P, Farndale RW, Hogwood J, Rankin A, Stephens JC, Tom BD, Walton J, Dudbridge F, Ouwehand WH, Goodall AH, et al. Mapping the platelet profile for functional genomic studies and demonstration of the effect size of the GP6 locus. Journal of Thrombosis and Haemostasis : Jth. 5: 1756-65. PMID 17663743 DOI: 10.1111/J.1538-7836.2007.02632.X |
0.369 |
|
2007 |
Farndale RW, Slatter DA, Siljander PR, Jarvis GE. Platelet receptor recognition and cross-talk in collagen-induced activation of platelets. Journal of Thrombosis and Haemostasis : Jth. 220-9. PMID 17635730 DOI: 10.1111/J.1538-7836.2007.02521.X |
0.504 |
|
2007 |
Tulla M, Huhtala M, Jäälinoja J, Käpylä J, Farndale RW, Ala-Kokko L, Johnson MS, Heino J. Analysis of an ascidian integrin provides new insight into early evolution of collagen recognition. Febs Letters. 581: 2434-40. PMID 17485091 DOI: 10.1016/J.Febslet.2007.04.054 |
0.467 |
|
2007 |
Butler LM, Metson-Scott T, Felix J, Abhyankar A, Rainger GE, Farndale RW, Watson SP, Nash GB. Sequential adhesion of platelets and leukocytes from flowing whole blood onto a collagen-coated surface: requirement for a GpVI-binding site in collagen. Thrombosis and Haemostasis. 97: 814-21. PMID 17479193 DOI: 10.1160/Th06-08-0439 |
0.484 |
|
2007 |
Lisman T, Farndale RW, Groot dP. A mechanism to safeguard platelet adhesion under high-shear flow: von Willebrand factor–glycoprotein Ib and integrin α2β1–collagen interactions make complementary, collagen-type-specific contributions to adhesion: a rebuttal Journal of Thrombosis and Haemostasis. 5: 1338-1339. PMID 17403111 DOI: 10.1111/J.1538-7836.2007.02538.X |
0.43 |
|
2007 |
Fung CY, Cendana C, Farndale RW, Mahaut-Smith MP. Primary and secondary agonists can use P2X(1) receptors as a major pathway to increase intracellular Ca(2+) in the human platelet. Journal of Thrombosis and Haemostasis : Jth. 5: 910-7. PMID 17362227 DOI: 10.1111/J.1538-7836.2007.02525.X |
0.364 |
|
2007 |
Smethurst PA, Onley DJ, Jarvis GE, O'Connor MN, Knight CG, Herr AB, Ouwehand WH, Farndale RW. Structural basis for the platelet-collagen interaction: the smallest motif within collagen that recognizes and activates platelet Glycoprotein VI contains two glycine-proline-hydroxyproline triplets. The Journal of Biological Chemistry. 282: 1296-304. PMID 17085439 DOI: 10.1074/Jbc.M606479200 |
0.496 |
|
2007 |
Pugh N, Farndale R. INVESTIGATION OF PLATELET BINDING TO COLLAGEN PEPTIDES UNDER FLOW CONDITIONS Journal of Thrombosis and Haemostasis. 5: P-W-261-P-W-261. DOI: 10.1111/J.1538-7836.2007.TB02820.X |
0.329 |
|
2007 |
Munnix I, Cosemans J, van der Meijden P, van Montfoort A, Feijge M, Farndale R, Koyasu S, Heller R, Sage S, Jackson S, Heemskerk J. SPECIFIC ROLES OF PHOSPHOINOSITIDE 3-KINASE ISOFORMS ALPHA AND BETA IN GLYCOPROTEIN VI-INDUCED PLATELET SIGNALING TO PROCOAGULANT ACTIVITY Journal of Thrombosis and Haemostasis. 5: P-W-235-P-W-235. DOI: 10.1111/J.1538-7836.2007.Tb02794.X |
0.343 |
|
2007 |
Hamaia S, Allcott N, Peachey A, Fernandez R, Raynal N, Farndale R. CONSTITUTIVELY ACTIVE OR INACTIVE I DOMAINS AS PROBES FOR INTEGRIN BINDING TO COLLAGEN Journal of Thrombosis and Haemostasis. 5: P-T-419-P-T-419. DOI: 10.1111/J.1538-7836.2007.Tb02175.X |
0.397 |
|
2007 |
Fung CYE, Cendana C, Mahaut-smith MP, Farndale RW. Primary and secondary agonists can use P2X receptors as a major pathway to increase intracellular Ca in the human platelet Scopus. DOI: 10.1111/J.1538-7836.2007.02525.X/Abstract |
0.346 |
|
2006 |
Lee FA, van Lier M, Relou IA, Foley L, Akkerman JW, Heijnen HF, Farndale RW. Lipid rafts facilitate the interaction of PECAM-1 with the glycoprotein VI-FcR gamma-chain complex in human platelets. The Journal of Biological Chemistry. 281: 39330-8. PMID 17068334 DOI: 10.1074/Jbc.M607930200 |
0.397 |
|
2006 |
Jennings NS, Smethurst PA, Knight CG, O'Connor MN, Joutsi-Korhonen L, Stafford P, Stephens J, Garner SF, Harmer IJ, Farndale RW, Watkins NA, Ouwehand WH. Production of calmodulin-tagged proteins in Drosophila Schneider S2 cells: a novel system for antigen production and phage antibody isolation. Journal of Immunological Methods. 316: 75-83. PMID 17027020 DOI: 10.1016/J.Jim.2006.08.003 |
0.303 |
|
2006 |
O'Connor MN, Smethurst PA, Davies LW, Joutsi-Korhonen L, Onley DJ, Herr AB, Farndale RW, Ouwehand WH. Selective blockade of glycoprotein VI clustering on collagen helices. The Journal of Biological Chemistry. 281: 33505-10. PMID 16956881 DOI: 10.1074/Jbc.M606480200 |
0.49 |
|
2006 |
Lisman T, Raynal N, Groeneveld D, Maddox B, Peachey AR, Huizinga EG, de Groot PG, Farndale RW. A single high-affinity binding site for von Willebrand factor in collagen III, identified using synthetic triple-helical peptides. Blood. 108: 3753-6. PMID 16912226 DOI: 10.1182/Blood-2006-03-011965 |
0.53 |
|
2006 |
Ricard-Blum S, Beraud M, Raynal N, Farndale RW, Ruggiero F. Structural requirements for heparin/heparan sulfate binding to type V collagen. The Journal of Biological Chemistry. 281: 25195-204. PMID 16815843 DOI: 10.1074/Jbc.M603096200 |
0.455 |
|
2006 |
Lebbink RJ, de Ruiter T, Adelmeijer J, Brenkman AB, van Helvoort JM, Koch M, Farndale RW, Lisman T, Sonnenberg A, Lenting PJ, Meyaard L. Collagens are functional, high affinity ligands for the inhibitory immune receptor LAIR-1. The Journal of Experimental Medicine. 203: 1419-25. PMID 16754721 DOI: 10.1084/Jem.20052554 |
0.393 |
|
2006 |
Slatter DA, Foley LA, Peachey AR, Nietlispach D, Farndale RW. Rapid synthesis of a register-specific heterotrimeric type I collagen helix encompassing the integrin alpha2beta1 binding site. Journal of Molecular Biology. 359: 289-98. PMID 16631195 DOI: 10.1016/J.Jmb.2006.02.071 |
0.399 |
|
2006 |
Sabri S, Foudi A, Boukour S, Franc B, Charrier S, Jandrot-Perrus M, Farndale RW, Jalil A, Blundell MP, Cramer EM, Louache F, Debili N, Thrasher AJ, Vainchenker W. Deficiency in the Wiskott-Aldrich protein induces premature proplatelet formation and platelet production in the bone marrow compartment. Blood. 108: 134-40. PMID 16522820 DOI: 10.1182/Blood-2005-03-1219 |
0.421 |
|
2006 |
Farndale RW. Collagen-induced platelet activation. Blood Cells, Molecules & Diseases. 36: 162-5. PMID 16464621 DOI: 10.1016/J.Bcmd.2005.12.016 |
0.481 |
|
2006 |
Raynal N, Hamaia SW, Siljander PR, Maddox B, Peachey AR, Fernandez R, Foley LJ, Slatter DA, Jarvis GE, Farndale RW. Use of synthetic peptides to locate novel integrin alpha2beta1-binding motifs in human collagen III. The Journal of Biological Chemistry. 281: 3821-31. PMID 16326707 DOI: 10.1074/Jbc.M509818200 |
0.432 |
|
2006 |
Smethurst PA, O'Connor MN, Jones CI, Watkins NA, Rankin A, Garner SF, Joutsi-Korhonen L, Farndale RW, Goodall AH, Ouwehand WH. Platelet biology: collagen activation mechanisms and their relevance to transfusion medicine Isbt Science Series. 1: 103-106. DOI: 10.1111/j.1751-2824.2006.00021.x |
0.332 |
|
2006 |
O'CONNOR MN, SMETHURST PA, FARNDALE RW, OUWEHAND WH. Gain- and loss-of-function mutants confirm the importance of apical residues to the primary interaction of human glycoprotein VI with collagen Journal of Thrombosis and Haemostasis. 4: 869-873. DOI: 10.1111/J.1538-7836.2005.01764.X |
0.444 |
|
2006 |
Smethurst PA, Gladigau EL, Garner SF, Davies LW, Rankin A, Campbell K, Yusuf R, Farndale RW, Tillyer L, Ouwehand WH. P49 First UK Report of a Case of Glycoprotein VI Deficiency in a 33-Year-Old Patient with Moderate Thrombocytopenia and Autoantibodies Against the Immunoglobulin-Like Domains of the Receptor Transfusion Medicine. 16: 45-46. DOI: 10.1111/J.1365-3148.2006.00694_49.X |
0.433 |
|
2006 |
Penz S, Reininger A, Brandl R, Farndale R, Siess W. We-W40:7 Glycoprotein VI inhibition is more potent than ADP-receptor antagonism or aspirin in reducing plaque-induced platelet thrombus formation Atherosclerosis Supplements. 7: 326. DOI: 10.1016/S1567-5688(06)81301-2 |
0.306 |
|
2005 |
Riba R, Sharifi M, Farndale RW, Naseem KM. Regulation of platelet guanylyl cyclase by collagen: evidence that Glycoprotein VI mediates platelet nitric oxide synthesis in response to collagen. Thrombosis and Haemostasis. 94: 395-403. PMID 16113831 DOI: 10.1160/Th05-01-0027 |
0.5 |
|
2005 |
Penz S, Reininger AJ, Brandl R, Goyal P, Rabie T, Bernlochner I, Rother E, Goetz C, Engelmann B, Smethurst PA, Ouwehand WH, Farndale R, Nieswandt B, Siess W. Human atheromatous plaques stimulate thrombus formation by activating platelet glycoprotein VI The Faseb Journal. 19: 898-909. PMID 15923400 DOI: 10.1096/Fj.04-2748Com |
0.436 |
|
2005 |
de Bono B, Pace N, Farndale R. Formation of Platelet plug Reactome - a Curated Knowledgebase of Biological Pathways. 13. DOI: 10.3180/React_20.1 |
0.409 |
|
2005 |
Freson K, Labarque V, Thys C, Wittevrongel C, De Vos R, Farndale R, Van Geet C. Increased Bleeding Tendency in a Patient with Caffey Disease Due to a COL1A1 Mutation and a Defect in Platelet Morphology and Function. Blood. 106: 736-736. DOI: 10.1182/Blood.V106.11.736.736 |
0.475 |
|
2005 |
Lisman T, Raynal N, Groeneveld D, Maddox B, Peachey T, Huizinga EG, de Groot PG, Farndale RW. Identification of the von Willebrand Factor Binding Site in Collagen Using Triple Helical Peptides. Blood. 106: 413-413. DOI: 10.1182/Blood.V106.11.413.413 |
0.497 |
|
2005 |
Hughes DL, Stafford P, Hamaia SW, Harmer IJ, Schoolmeester A, Deckmyn H, Farndale RW, Ouwehand WH, Watkins NA. Platelet integrin α2 I-domain specific antibodies produced via domain specific DNA vaccination combined with variable gene phage display Thrombosis and Haemostasis. 94: 1318-1326. DOI: 10.1160/Th05-06-0410 |
0.334 |
|
2005 |
Fung CYE, Brearley CA, Farndale RW, Mahaut-Smith MP. A major role for P2X1 receptors in the early collagen-evoked intracellular Ca2+ responses of human platelets Thrombosis and Haemostasis. 94: 37-40. DOI: 10.1160/Th04-11-0732 |
0.336 |
|
2005 |
LIER M, LEE F, FARNDALE RW, GORTER G, VERHOEF S, OHNO-IWASHITA Y, AKKERMAN JN, HEIJNEN HFG. Adhesive surface determines raft composition in platelets adhered under flow Journal of Thrombosis and Haemostasis. 3: 2514-2525. DOI: 10.1111/J.1538-7836.2005.01597.X |
0.477 |
|
2004 |
Käpylä J, Jäälinoja J, Tulla M, Ylöstalo J, Nissinen L, Viitasalo T, Vehviläinen P, Marjomäki V, Nykvist P, Säämänen AM, Farndale RW, Birk DE, Ala-Kokko L, Heino J. The fibril-associated collagen IX provides a novel mechanism for cell adhesion to cartilaginous matrix. The Journal of Biological Chemistry. 279: 51677-87. PMID 15383545 DOI: 10.1074/Jbc.M409412200 |
0.491 |
|
2004 |
Siljander PR, Hamaia S, Peachey AR, Slatter DA, Smethurst PA, Ouwehand WH, Knight CG, Farndale RW. Integrin activation state determines selectivity for novel recognition sites in fibrillar collagens. The Journal of Biological Chemistry. 279: 47763-72. PMID 15345717 DOI: 10.1074/Jbc.M404685200 |
0.431 |
|
2004 |
Knight CG, Onley CM, Farndale RW. Peptide synthesis in the study of collagen-platelet interactions. Methods in Molecular Biology (Clifton, N.J.). 273: 349-64. PMID 15308811 DOI: 10.1385/1-59259-783-1:349 |
0.426 |
|
2004 |
Sabri S, Jandrot-Perrus M, Bertoglio J, Farndale RW, Mas VM, Debili N, Vainchenker W. Differential regulation of actin stress fiber assembly and proplatelet formation by alpha2beta1 integrin and GPVI in human megakaryocytes. Blood. 104: 3117-25. PMID 15265786 DOI: 10.1182/Blood-2003-12-4398 |
0.398 |
|
2004 |
Farndale RW, Hargreaves PG, Dietrich JL, Keogh RJ. Measurement of platelet arachidonic acid metabolism. Methods in Molecular Biology (Clifton, N.J.). 272: 121-33. PMID 15226540 DOI: 10.1385/1-59259-782-3:121 |
0.419 |
|
2004 |
Barrow AD, Astoul E, Floto A, Brooke G, Relou IAM, Jennings NS, Smith KGC, Ouwehand W, Farndale RW, Alexander DR, Trowsdale J. Cutting Edge: TREM-Like Transcript-1, a Platelet Immunoreceptor Tyrosine-Based Inhibition Motif Encoding Costimulatory Immunoreceptor that Enhances, Rather than Inhibits, Calcium Signaling via SHP-2 Journal of Immunology. 172: 5838-5842. PMID 15128762 DOI: 10.4049/Jimmunol.172.10.5838 |
0.432 |
|
2004 |
Farndale RW, Sixma JJ, Barnes MJ, De Groot PG. The role of collagen in thrombosis and hemostasis Journal of Thrombosis and Haemostasis. 2: 561-573. PMID 15102010 DOI: 10.1111/J.1538-7836.2004.00665.X |
0.393 |
|
2004 |
Joutsi-Korhonen L, Preston S, Smethurst PA, Ijsseldijk M, Schaffner-Reckinger E, Armour KL, Watkins NA, Clark MR, de Groot PG, Farndale RW, Ouwehand WH, Williamson LM. The effect of recombinant IgG antibodies against the leucine-33 form of the platelet beta3 integrin (HPA-1a) on platelet function. Thrombosis and Haemostasis. 91: 743-54. PMID 15045136 DOI: 10.1160/Th03-07-0484 |
0.427 |
|
2004 |
Emsley J, Knight CG, Farndale RW, Barnes MJ. Structure of the integrin alpha2beta1-binding collagen peptide. Journal of Molecular Biology. 335: 1019-28. PMID 14698296 DOI: 10.1016/J.Jmb.2003.11.030 |
0.434 |
|
2004 |
Siljander PR-, Munnix ICA, Smethurst PA, Deckmyn H, Lindhout T, Ouwehand WH, Farndale RW, Heemskerk JWM. Platelet receptor interplay regulates collagen-induced thrombus formation in flowing human blood Blood. 103: 1333-1341. PMID 14563646 DOI: 10.1182/Blood-2003-03-0889 |
0.469 |
|
2004 |
Smethurst PA, Joutsi-Korhonen L, O'Connor MN, Wilson E, Jennings NS, Garner SF, Zhang Y, Knight CG, Dafforn TR, Buckle A, IJsseldijk MJ, De Groot PG, Watkins NA, Farndale RW, Ouwehand WH. Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody. Blood. 103: 903-11. PMID 14504096 DOI: 10.1182/Blood-2003-01-0308 |
0.473 |
|
2004 |
Reininger AJ, Brandl R, Penz S, Goyal P, Rabie T, Rother E, Goetz C, Engelmann B, Farndale R, Nieswandt B, Siess W. Human Atheromatous Plaques Stimulate Thrombus Formation by Activating Platelet Glycoprotein VI. Blood. 104: 2623-2623. DOI: 10.1182/Blood.V104.11.2623.2623 |
0.445 |
|
2003 |
Farndale RW, Siljander PR, Onley DJ, Sundaresan P, Knight CG, Barnes MJ. Collagen-platelet interactions: recognition and signalling. Biochemical Society Symposium. 81-94. PMID 14587284 DOI: 10.1042/Bss0700081 |
0.475 |
|
2003 |
Lahav J, Wijnen EM, Hess O, Hamaia SW, Griffiths D, Makris M, Knight CG, Essex DW, Farndale RW. Enzymatically catalyzed disulfide exchange is required for platelet adhesion to collagen via integrin alpha2beta1. Blood. 102: 2085-92. PMID 12791669 DOI: 10.1182/Blood-2002-06-1646 |
0.497 |
|
2003 |
Perret S, Eble JA, Siljander PRM, Merle C, Farndale RW, Theisen M, Ruggiero F. Prolyl hydroxylation of collagen type I is required for efficient binding to integrin α1β1 and platelet glycoprotein VI but not to α2β1 Journal of Biological Chemistry. 278: 29873-29879. PMID 12771137 DOI: 10.1074/Jbc.M304073200 |
0.542 |
|
2003 |
Joutsi-Korhonen L, Smethurst PA, Rankin A, Gray E, IJsseldijk M, Onley CM, Watkins NA, Williamson LM, Goodall AH, de Groot PG, Farndale RW, Ouwehand WH. The low-frequency allele of the platelet collagen signaling receptor glycoprotein VI is associated with reduced functional responses and expression. Blood. 101: 4372-9. PMID 12560230 DOI: 10.1182/Blood-2002-08-2591 |
0.451 |
|
2003 |
Elton CM, Smethurst PA, Eggleton P, Farndale RW. Physical and functional interaction between cell-surface calreticulin and the collagen receptors integrin alpha2beta1 and glycoprotein VI in human platelets. Thrombosis and Haemostasis. 88: 648-54. PMID 12362238 |
0.377 |
|
2002 |
Sundaresan P, Farndale RW. P38 mitogen-activated protein kinase dephosphorylation is regulated by protein phosphatase 2A in human platelets activated by collagen. Febs Letters. 528: 139-44. PMID 12297294 DOI: 10.1016/S0014-5793(02)03277-5 |
0.395 |
|
2002 |
Lahav J, Jurk K, Hess O, Barnes MJ, Farndale RW, Luboshitz J, Kehrel BE. Sustained integrin ligation involves extracellular free sulfhydryls and enzymatically catalyzed disulfide exchange. Blood. 100: 2472-8. PMID 12239158 DOI: 10.1182/Blood-2001-12-0339 |
0.432 |
|
2002 |
Ruehl M, Somasundaram R, Schoenfelder I, Farndale RW, Knight CG, Schmid M, Ackermann R, Riecken EO, Zeitz M, Schuppan D. The epithelial mitogen keratinocyte growth factor binds to collagens via the consensus sequence glycine-proline-hydroxyproline. The Journal of Biological Chemistry. 277: 26872-8. PMID 11973338 DOI: 10.1074/jbc.M202335200 |
0.368 |
|
2002 |
Aquilina A, Korda M, Bergelson JM, Humphries MJ, Farndale RW, Tuckwell D. A novel gain-of-function mutation of the integrin alpha2 VWFA domain. European Journal of Biochemistry / Febs. 269: 1136-44. PMID 11856343 DOI: 10.1046/J.0014-2956.2001.02740.X |
0.413 |
|
2002 |
KNIGHT C, MORTON L, ONLEY D, PEACHEY A, FARNDALE R, BARNES M. Identification of an α2β1-binding sequence in collagen I International Journal of Experimental Pathology. 79: A33-A34. DOI: 10.1046/J.1365-2613.1998.T01-25-750408.X |
0.374 |
|
2002 |
Somasundaram R, Ruehl M, Schoenfelder I, Farndale R, Knight G, Schmid M, Ackermann R, Zeitz M, Schuppan D. Liver/intestinal collagens type I, III and VI bind keratinocyte growth factor (KGF/FGF-7) via the collagenous binding motives (GPO) X and (GPP) X Journal of Hepatology. 36: 63. DOI: 10.1016/S0168-8278(02)80209-4 |
0.344 |
|
2002 |
Ruehl M, Somasundaram R, Farndale R, Knight G, Schmid M, Ackermann R, Zeitz M, Schuppan D. The inactive form of matrix metalloproteinase-9 is stored by liver collagens via the collagenous motive (GLY-PRO-HYP) X Journal of Hepatology. 36: 59. DOI: 10.1016/S0168-8278(02)80192-1 |
0.349 |
|
2001 |
Jones KL, Hughan SC, Dopheide SM, Farndale RW, Jackson SP, Jackson DE. Platelet endothelial cell adhesion molecule-1 is a negative regulator of platelet-collagen interactions. Blood. 98: 1456-63. PMID 11520795 DOI: 10.1182/Blood.V98.5.1456 |
0.503 |
|
2001 |
Siljander P, Farndale RW, Feijge MA, Comfurius P, Kos S, Bevers EM, Heemskerk JW. Platelet adhesion enhances the glycoprotein VI-dependent procoagulant response: Involvement of p38 MAP kinase and calpain. Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 618-27. PMID 11304481 DOI: 10.1161/01.Atv.21.4.618 |
0.46 |
|
2001 |
Achison M, Elton CM, Hargreaves PG, Knight CG, Barnes MJ, Farndale RW. Integrin-independent tyrosine phosphorylation of p125(fak) in human platelets stimulated by collagen. The Journal of Biological Chemistry. 276: 3167-74. PMID 11110790 DOI: 10.1074/Jbc.M007186200 |
0.437 |
|
2001 |
Ruehl M, Somasundaram R, Farndale R, Knight G, Schmid M, Ackermann R, Riecken E, Schuppan D. Synthetic collagen-oligopeptides inhibit binding of platelet derived growth factor BB to the hepatic extracellular matrix Journal of Hepatology. 34: 51. DOI: 10.1016/S0168-8278(01)81044-8 |
0.45 |
|
2001 |
Ruehl M, Schoenfelder I, Farndale R, Knight G, Somasundaram R, Schuppan D. Keratinocyte growth factor binds to collagens of the gastrointestinal tract: Identification of the collagen binding structure Gastroenterology. 120: A695. DOI: 10.1016/S0016-5085(08)83459-2 |
0.39 |
|
2000 |
Tuckwell DS, Smith L, Korda M, Askari JA, Santoso S, Barnes MJ, Farndale RW, Humphries MJ. Monoclonal antibodies identify residues 199-216 of the integrin alpha2 vWFA domain as a functionally important region within alpha2beta1. The Biochemical Journal. 350: 485-93. PMID 10947963 DOI: 10.1042/0264-6021:3500485 |
0.418 |
|
2000 |
Niedergang F, Alcover A, Knight CG, Farndale RW, Barnes MJ, Francischetti IM, Bon C, Leduc M. Convulxin binding to platelet receptor GPVI: competition with collagen related peptides. Biochemical and Biophysical Research Communications. 273: 246-50. PMID 10873594 DOI: 10.1006/Bbrc.2000.2940 |
0.483 |
|
2000 |
Emsley J, Knight CG, Farndale RW, Barnes MJ, Liddington RC. Structural basis of collagen recognition by integrin alpha2beta1. Cell. 101: 47-56. PMID 10778855 DOI: 10.1016/S0092-8674(00)80622-4 |
0.366 |
|
2000 |
Emsley J, Knight C, Farndale R, Barnes M, Liddington R. STRUCTURE OF THE INTEGRIN α2β1 INSERTED DOMAIN IN COMPLEX WITH A HOMOTRIMERIC COLLAGEN PEPTIDE Biochemical Society Transactions. 28: A86-A86. DOI: 10.1042/Bst028A086B |
0.351 |
|
2000 |
Onley DJ, Knight CG, Barnes MJ, Farndale RW. Micromolar Ca2+ Concentrations are Essential for Mg2+-dependent Binding of Collagen by the Integrin α2β1 in Human Platelets Biochemical Society Transactions. 28: A85-A85. DOI: 10.1042/Bst028A085C |
0.407 |
|
2000 |
Tuckwell DS, Smith L, Korda M, Askari JA, Santoso S, Barnes MJ, Farndale RW, Humphries MJ. Monoclonal antibodies identify residues 199–216 of the integrin α2 vWFA domain as a functionally important region within α2β1 Biochemical Journal. 350: 485-493. DOI: 10.1042/Bj3500485 |
0.414 |
|
1999 |
Barnes MJ, Farndale RW. Collagens and atherosclerosis Experimental Gerontology. 34: 513-525. PMID 10817807 DOI: 10.1016/S0531-5565(99)00038-8 |
0.442 |
|
1999 |
Knight CG, Morton LF, Onley DJ, Peachey AR, Ichinohe T, Okuma M, Farndale RW, Barnes MJ. Collagen-platelet interaction: Gly-Pro-Hyp is uniquely specific for platelet Gp VI and mediates platelet activation by collagen. Cardiovascular Research. 41: 450-7. PMID 10341844 DOI: 10.1016/S0008-6363(98)00306-X |
0.483 |
|
1999 |
Siljander P, Vuist W, Breikers G, Reutelingsperger C, Barnes M, Graham Knight C, Lassila R, Farndale R, Heemskerk J. Function of Glycoprotein VI and Integrin α2β1 in the Procoagulant Response of Single, Collagen-Adherent Platelets Thrombosis and Haemostasis. 81: 782-792. DOI: 10.1055/S-0037-1614571 |
0.503 |
|
1999 |
Knight C, Morton L, Peachey A, Tuckwell D, Farndale R, Barnes M. THE COLLAGEN SEQUENCE, GFOGER, IS A BINDING SITE FOR INTEGRIN α1 AND α2 A-DOMAINS AND FULLY MEDIATES α2β1-DEPENDENT CELL-RECOGNITION BY COLLAGEN Biochemical Society Transactions. 27: A144-A144. DOI: 10.1042/Bst027A144B |
0.376 |
|
1999 |
JUŠKA A, FARNDALE RW. Inhibition of human platelet adenylate cyclase activity by adrenaline, thrombin and collagen: analysis and reinterpretation of experimental data Biochemical Journal. 340: 245. DOI: 10.1042/Bj3400245 |
0.417 |
|
1999 |
JUšKA A, FARNDALE RW. Inhibition of human platelet adenylate cyclase activity by adrenaline, thrombin and collagen: analysis and reinterpretation of experimental data Biochemical Journal. 340: 245-253. DOI: 10.1042/BJ3400245 |
0.306 |
|
1999 |
ASSELIN J, KNIGHT CG, FARNDALE RW, BARNES MJ, WATSON SP. Monomeric (glycine-proline-hydroxyproline)10 repeat sequence is a partial agonist of the platelet collagen receptor glycoprotein VI Biochemical Journal. 339: 413-418. DOI: 10.1042/Bj3390413 |
0.468 |
|
1998 |
Barnes MJ, Knight CG, Farndale RW. The collagen-platelet interaction. Current Opinion in Hematology. 5: 314-20. PMID 9776209 DOI: 10.1097/00062752-199809000-00002 |
0.492 |
|
1998 |
Kehrel B, Wierwille S, Clemetson KJ, Anders O, Steiner M, Graham Knight C, Farndale RW, Okuma M, Barnes MJ. Glycoprotein VI Is a Major Collagen Receptor for Platelet Activation: It Recognizes the Platelet-Activating Quaternary Structure of Collagen, Whereas CD36, Glycoprotein IIb/IIIa, and von Willebrand Factor Do Not Blood. 91: 491-499. DOI: 10.1182/Blood.V91.2.491 |
0.476 |
|
1997 |
Gibbins JM, Okuma M, Farndale R, Barnes M, Watson SP. Glycoprotein VI is the collagen receptor in platelets which underlies tyrosine phosphorylation of the Fc receptor γ-chain Febs Letters. 413: 255-259. PMID 9280292 DOI: 10.1016/S0014-5793(97)00926-5 |
0.384 |
|
1997 |
Heemskerk JWM, Feijge MAH, Sage SO, Farndale RW. Human platelet activation is inhibited upstream of the activation of phospholipase A2 by U73343 Biochemical Pharmacology. 53: 1257-1262. PMID 9214686 DOI: 10.1016/S0006-2952(96)00888-X |
0.394 |
|
1997 |
Morton LF, Peachey AR, Knight CG, Farndale RW, Barnes MJ. The platelet reactivity of synthetic peptides based on the collagen III fragment alpha1(III)CB4. Evidence for an integrin alpha2beta1 recognition site involving residues 522-528 of the alpha1(III) collagen chain. The Journal of Biological Chemistry. 272: 11044-8. PMID 9110997 DOI: 10.1074/jbc.272.17.11044 |
0.336 |
|
1997 |
Heemskerk JWM, Farndale RW, Sage SO. Effects of U73122 and U73343 on human platelet calcium signalling and protein tyrosine phosphorylation Biochimica Et Biophysica Acta - Molecular Cell Research. 1355: 81-88. PMID 9030204 DOI: 10.1016/S0167-4889(96)00113-9 |
0.379 |
|
1997 |
Asselin J, Gibbins JM, Achison M, Lee YH, Morton LF, Farndale RW, Barnes MJ, Watson SP. A Collagen-Like Peptide Stimulates Tyrosine Phosphorylation of syk and Phospholipase Cγ2 in Platelets Independent of the Integrin α2β1 Blood. 89: 1235-1242. DOI: 10.1182/Blood.V89.4.1235 |
0.488 |
|
1997 |
Heath MF, Farndale RW, Napthine CS, Hayes LJ, Evans RJ. Molecular mechanism of resistance of equine (Equus caballus) platelets to α2-adrenergic regulation Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology. 118: 889-893. DOI: 10.1016/S0305-0491(97)00305-2 |
0.445 |
|
1997 |
Barnes M, Knight C, Farndale R. 1.W01.1 Collagens and atherosclerosis: Collagen-cell interaction Atherosclerosis. 134: 8. DOI: 10.1016/S0021-9150(97)88142-7 |
0.37 |
|
1996 |
Barnes MJ, Knight CG, Farndale RW. The use of collagen-based model peptides to investigate platelet-reactive sequences in collagen. Biopolymers. 40: 383-97. PMID 8765609 DOI: 10.1002/(Sici)1097-0282(1996)40:4<383::Aid-Bip4>3.0.Co;2-S |
0.472 |
|
1996 |
Achison M, Joel C, Hargreaves PG, Sage SO, Barnes MJ, Farndale RW, Sageis SO. Signals elicited from human platelets by synthetic, triple helical, collagen-like peptides Blood Coagulation and Fibrinolysis. 7: 149-152. PMID 8735805 DOI: 10.1097/00001721-199603000-00009 |
0.377 |
|
1996 |
Gibbins J, Asselin J, Farndale R, Barnes M, Law CL, Watson SP. Tyrosine phosphorylation of the Fc receptor γ-chain in collagen- stimulated platelets Journal of Biological Chemistry. 271: 18095-18099. PMID 8663460 DOI: 10.1074/Jbc.271.30.18095 |
0.454 |
|
1996 |
Saklatvala J, Rawlinson L, Waller RJ, Sarsfield S, Lee JC, Morton LF, Barnes MJ, Farndale RW. Role for p38 mitogen-activated protein kinase in platelet aggregation caused by collagen or a thromboxane analogue. The Journal of Biological Chemistry. 271: 6586-9. PMID 8636072 DOI: 10.1074/Jbc.271.12.6586 |
0.439 |
|
1996 |
Jenner S, Farndale RW, Sage SO. Wortmannin inhibits store-mediated calcium entry and protein tyrosine phosphorylation in human platelets Febs Letters. 381: 249-251. PMID 8601465 DOI: 10.1016/0014-5793(96)00130-5 |
0.323 |
|
1996 |
Farndale RW, Napthine CS, Evans RJ, Hayes LJ, Heath MF. The inhibition of adenylate cyclase in equine platelets by collagen and by platelet-activating factor Platelets. 7: 43-46. DOI: 10.3109/09537109609079508 |
0.441 |
|
1996 |
Hargreaves PG, Jenner S, Merritt JE, Sage SO, Farndale RW. lonomycin-stimulated Arachidonic Acid Release in Human Platelets: a Role for Protein Kinase C and Tyrosine Phosphorylation Thrombosis and Haemostasis. 76: 248-252. DOI: 10.1055/S-0038-1650563 |
0.315 |
|
1995 |
Farndale RW, Barnes MJ. Transmembrane signalling: protein tyrosine phosphorylation and platelet activation Equine Veterinary Journal. 27: 407-410. PMID 8565936 DOI: 10.1111/J.2042-3306.1995.Tb04419.X |
0.365 |
|
1995 |
Grainger DJ, Wakefield L, Bethell HW, Farndale RW, Metcalfe JC. Release and activation of platelet latent TGF-beta in blood clots during dissolution with plasmin. Nature Medicine. 1: 932-7. PMID 7585220 DOI: 10.1038/Nm0995-932 |
0.403 |
|
1995 |
Morton LF, Hargreaves PG, Farndale RW, Young RD, Barnes MJ. Integrin alpha 2 beta 1-independent activation of platelets by simple collagen-like peptides: collagen tertiary (triple-helical) and quaternary (polymeric) structures are sufficient alone for alpha 2 beta 1-independent platelet reactivity. The Biochemical Journal. 306: 337-44. PMID 7534064 DOI: 10.1042/Bj3060337 |
0.458 |
|
1995 |
Morton LF, Hargreaves PG, Farndale RW, Young RD, Barnes MJ. Integrin α2β1-independent activation of platelets by simple collagen-like peptides: collagen tertiary (triple-helical) and quaternary (polymeric) structures are sufficient alone for α2β1-independent platelet reactivity Biochemical Journal. 306: 337-344. DOI: 10.1042/BJ3060337 |
0.377 |
|
1994 |
Sargeant P, Farndale RW, Sage SO. The imidazole antimycotics econazole and miconazole reduce agonist-evoked protein-tyrosine phosphorylation and evoke membrane depolarisation in human platelets: cautions for their use in studying Ca2+ signalling pathways Cell Calcium. 16: 413-418. PMID 7532106 DOI: 10.1016/0143-4160(94)90034-5 |
0.343 |
|
1994 |
Hargreaves PG, Licking EF, Sargeant P, Sage SO, Barnes MJ, Farndale RW. The Tyrosine Kinase Inhibitors, Genistein and Methyl 2,5-Dihydroxycinnamate, Inhibit the Release of (3H)Arachidonate from Human Platelets Stimulated by Thrombin or Collagen Thrombosis and Haemostasis. 72: 634-642. DOI: 10.1055/S-0038-1648927 |
0.35 |
|
1993 |
Sandy JR, Farndale RW, Meikle MC. Recent advances in understanding mechanically induced bone remodeling and their relevance to orthodontic theory and practice American Journal of Orthodontics and Dentofacial Orthopedics. 103: 212-222. PMID 8456777 DOI: 10.1016/0889-5406(93)70002-6 |
0.308 |
|
1993 |
Sargeant P, Farndale RW, Sage SO. The tyrosine kinase inhibitors methyl 2,5-dihydroxycinnamate and genistein reduce thrombin-evoked tyrosine phosphorylation and Ca2+ entry in human platelets Febs Letters. 315: 242-246. PMID 8422913 DOI: 10.1016/0014-5793(93)81172-V |
0.344 |
|
1992 |
Farndale RW, Winkler AB, Martin BR, Barnes MJ. Inhibition of human platelet adenylate cyclase by collagen fibres. Effect of collagen is additive with that of adrenaline, but interactive with that of thrombin Biochemical Journal. 282: 25-32. PMID 1311555 DOI: 10.1042/Bj2820025 |
0.473 |
|
1991 |
Wadman IA, Farndale RW, Martin BR. Evidence for regulation of human platelet adenylate cyclase by phosphorylation. Inhibition by ATP and guanosine 5'-[beta-thio]diphosphate occur by distinct mechanisms. The Biochemical Journal. 621-30. PMID 1905923 DOI: 10.1042/Bj2760621 |
0.349 |
|
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