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Stefan Lutz - Publications

Affiliations: 
Chemistry Emory University, Atlanta, GA 
Area:
Protein Engineering
Website:
http://chemistry.emory.edu/home/people/faculty/lutz-stefan.html
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56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Jenkins MC, Lutz S. Encapsulin Nanocontainers as Versatile Scaffolds for the Development of Artificial Metabolons. Acs Synthetic Biology. PMID 33769792 DOI: 10.1021/acssynbio.0c00636  0.342
2018 Lee PG, Lee SH, Hong EY, Lutz S, Kim BG. Circular permutation of a bacterial tyrosinase enables efficient polyphenol-specific oxidation and quantitative preparation of orobol. Biotechnology and Bioengineering. PMID 30011063 DOI: 10.1002/Bit.26795  0.435
2018 Lutz S, Iamurri SM. Protein Engineering: Past, Present, and Future. Methods in Molecular Biology (Clifton, N.J.). 1685: 1-12. PMID 29086300 DOI: 10.1007/978-1-4939-7366-8_1  0.402
2017 Chen F, Zhang Y, Daugherty AB, Yang Z, Shaw R, Dong M, Lutz S, Benner SA. Biological phosphorylation of an Unnatural Base Pair (UBP) using a Drosophila melanogaster deoxynucleoside kinase (DmdNK) mutant. Plos One. 12: e0174163. PMID 28323896 DOI: 10.1371/Journal.Pone.0174163  0.778
2016 Matsuura MF, Winiger CB, Shaw RW, Kim MJ, Kim MS, Daugherty AB, Chen F, Moussatche P, Moses JD, Lutz S, Benner SA. A Single Deoxynucleoside Kinase Variant from Drosophila melanogaster Synthesizes Monophosphates of Nucleosides That Are Components of an Expanded Genetic System. Acs Synthetic Biology. PMID 27935283 DOI: 10.1021/Acssynbio.6B00228  0.772
2016 Lenz M, Meisner J, Quertinmont L, Lutz S, Kästner J, Nestl B. Asymmetric Ketone Reduction by Imine Reductases. Chembiochem : a European Journal of Chemical Biology. PMID 27911981 DOI: 10.1002/Cbic.201600647  0.329
2016 Muthu P, Lutz S. Quantitative Detection of Nucleoside Analogues by Multi-enzyme Biosensors using Time-Resolved Kinetic Measurements. Chemmedchem. PMID 26934468 DOI: 10.1002/Cmdc.201600096  0.334
2015 Daugherty AB, Horton JR, Cheng X, Lutz S. STRUCTURAL AND FUNCTIONAL CONSEQUENCES OF CIRCULAR PERMUTATION ON THE ACTIVE SITE OF OLD YELLOW ENZYME. Acs Catalysis. 5: 892-899. PMID 25692074 DOI: 10.1021/Cs501702K  0.795
2015 Quertinmont LT, Orru R, Lutz S. RApid Parallel Protein EvaluatoR (RAPPER), from gene to enzyme function in one day Chemical Communications. 51: 122-124. PMID 25384037 DOI: 10.1039/C4Cc08240K  0.436
2015 Quertinmont LT, Lutz S. Cell-free protein engineering of Old Yellow Enzyme 1 from Saccharomyces pastorianus Tetrahedron. DOI: 10.1016/J.Tet.2016.01.007  0.442
2014 Muthu P, Chen HX, Lutz S. Redesigning human 2'-deoxycytidine kinase enantioselectivity for L-nucleoside analogues as reporters in positron emission tomography. Acs Chemical Biology. 9: 2326-33. PMID 25079348 DOI: 10.1021/Cb500463F  0.39
2014 Lutz S, Daugherty AB, Yu Y, Qian Z. Generating random circular permutation libraries Methods in Molecular Biology. 1179: 245-258. PMID 25055783 DOI: 10.1007/978-1-4939-1053-3_17  0.765
2014 Fischereder E, Pressnitz D, Kroutil W, Lutz S. Engineering strictosidine synthase: Rational design of a small, focused circular permutation library of the β-propeller fold enzyme Bioorganic and Medicinal Chemistry. 22: 5633-5637. PMID 24996997 DOI: 10.1016/J.Bmc.2014.06.023  0.447
2013 Iamurri SM, Daugherty AB, Edmondson DE, Lutz S. Truncated FAD synthetase for direct biocatalytic conversion of riboflavin and analogs to their corresponding flavin mononucleotides. Protein Engineering, Design & Selection : Peds. 26: 791-5. PMID 24170887 DOI: 10.1093/Protein/Gzt055  0.775
2013 Daugherty AB, Govindarajan S, Lutz S. Improved biocatalysts from a synthetic circular permutation library of the flavin-dependent oxidoreductase old yellow enzyme. Journal of the American Chemical Society. 135: 14425-32. PMID 23987134 DOI: 10.1021/Ja4074886  0.802
2012 Daugherty AB, Muthu P, Lutz S. Novel protease inhibitors via computational redesign of subtilisin BPN' propeptide. Biochemistry. 51: 8247-55. PMID 23009354 DOI: 10.1021/Bi300832V  0.769
2012 Bornscheuer UT, Huisman GW, Kazlauskas RJ, Lutz S, Moore JC, Robins K. Engineering the third wave of biocatalysis. Nature. 485: 185-94. PMID 22575958 DOI: 10.1038/Nature11117  0.383
2011 Yu Y, Lutz S. Circular permutation: a different way to engineer enzyme structure and function. Trends in Biotechnology. 29: 18-25. PMID 21087800 DOI: 10.1016/J.Tibtech.2010.10.004  0.534
2011 Laszlo JA, Yu Y, Lutz S, Compton DL. Glycerol acyl-transfer kinetics of a circular permutated Candida antarctica lipase B Journal of Molecular Catalysis B: Enzymatic. 72: 175-180. DOI: 10.1016/J.Molcatb.2011.06.002  0.459
2010 Liu L, Murphy P, Baker D, Lutz S. Computational design of orthogonal nucleoside kinases. Chemical Communications (Cambridge, England). 46: 8803-5. PMID 20959903 DOI: 10.1039/C0Cc02961K  0.718
2010 Lutz S. Beyond directed evolution--semi-rational protein engineering and design. Current Opinion in Biotechnology. 21: 734-43. PMID 20869867 DOI: 10.1016/J.Copbio.2010.08.011  0.361
2010 Lutz S. Biochemistry. Reengineering enzymes. Science (New York, N.Y.). 329: 285-7. PMID 20647454 DOI: 10.1126/Science.1192224  0.353
2010 Reitinger S, Yu Y, Wicki J, Ludwiczek M, D'Angelo I, Baturin S, Okon M, Strynadka NC, Lutz S, Withers SG, McIntosh LP. Circular permutation of Bacillus circulans xylanase: a kinetic and structural study. Biochemistry. 49: 2464-74. PMID 20163191 DOI: 10.1021/Bi100036F  0.506
2010 Li Y, Soni PB, Liu L, Zhang X, Liotta DC, Lutz S. Synthesis of fluorescent nucleoside analogs as probes for 2′-deoxyribonucleoside kinases Bioorganic and Medicinal Chemistry Letters. 20: 841-843. PMID 20060716 DOI: 10.1016/J.Bmcl.2009.12.097  0.685
2010 Yu Y, Lutz S. Improved triglyceride transesterification by circular permuted Candida antarctica lipase B. Biotechnology and Bioengineering. 105: 44-50. PMID 19609971 DOI: 10.1002/Bit.22471  0.499
2009 Lutz S, Liu L, Liu Y. Engineering Kinases to Phosphorylate Nucleoside Analogs for Antiviral and Cancer Therapy. Chimia. 63: 737-744. PMID 20305804 DOI: 10.2533/Chimia.2009.737  0.751
2009 Qian Z, Horton JR, Cheng X, Lutz S. Structural redesign of lipase B from Candida antarctica by circular permutation and incremental truncation. Journal of Molecular Biology. 393: 191-201. PMID 19683009 DOI: 10.1016/J.Jmb.2009.08.008  0.609
2009 Liu L, Li Y, Liotta D, Lutz S. Directed evolution of an orthogonal nucleoside analog kinase via fluorescence-activated cell sorting. Nucleic Acids Research. 37: 4472-81. PMID 19474348 DOI: 10.1093/Nar/Gkp400  0.712
2009 Kazlauskas R, Lutz S. Engineering enzymes by 'intelligent' design. Current Opinion in Chemical Biology. 13: 1-2. PMID 19272831 DOI: 10.1016/J.Cbpa.2009.02.022  0.377
2009 Boone MA, McDonald FE, Lichter J, Lutz S, Cao R, Hardcastle KI. 1,5-Alpha-D-mannoseptanosides, ring-size isomers that are impervious to alpha-mannosidase-catalyzed hydrolysis. Organic Letters. 11: 851-4. PMID 19154123 DOI: 10.1021/Ol8028065  0.565
2008 Iyidogan P, Lutz S. Systematic exploration of active site mutations on human deoxycytidine kinase substrate specificity. Biochemistry. 47: 4711-20. PMID 18361501 DOI: 10.1021/Bi800157E  0.807
2007 Segura-Peña D, Lichter J, Trani M, Konrad M, Lavie A, Lutz S. Quaternary structure change as a mechanism for the regulation of thymidine kinase 1-like enzymes. Structure (London, England : 1993). 15: 1555-66. PMID 18073106 DOI: 10.1016/J.Str.2007.09.025  0.68
2007 Qian Z, Fields CJ, Lutz S. Investigating the structural and functional consequences of circular permutation on lipase B from Candida antarctica. Chembiochem : a European Journal of Chemical Biology. 8: 1989-96. PMID 17876754 DOI: 10.1002/Cbic.200700373  0.588
2007 Lutz S, Lichter J, Liu L. Exploiting temperature-dependent substrate promiscuity for nucleoside analogue activation by thymidine kinase from Thermotoga maritima. Journal of the American Chemical Society. 129: 8714-5. PMID 17592850 DOI: 10.1021/Ja0734391  0.764
2007 Gerth ML, Lutz S. Non-homologous recombination of deoxyribonucleoside kinases from human and Drosophila melanogaster yields human-like enzymes with novel activities. Journal of Molecular Biology. 370: 742-51. PMID 17543337 DOI: 10.1016/J.Jmb.2007.05.021  0.756
2007 Segura-Peña D, Lutz S, Monnerjahn C, Konrad M, Lavie A. Binding of ATP to TK1-like enzymes is associated with a conformational change in the quaternary structure. Journal of Molecular Biology. 369: 129-41. PMID 17407781 DOI: 10.1016/J.Jmb.2007.02.104  0.411
2007 Gerth ML, Lutz S. Mutagenesis of non-conserved active site residues improves the activity and narrows the specificity of human thymidine kinase 2. Biochemical and Biophysical Research Communications. 354: 802-7. PMID 17266931 DOI: 10.1016/J.Bbrc.2007.01.070  0.745
2007 Qian Z, Fields CJ, Yu Y, Lutz S. Recent progress in engineering alpha/beta hydrolase-fold family members. Biotechnology Journal. 2: 192-200. PMID 17183507 DOI: 10.1002/Biot.200600186  0.565
2005 Qian Z, Lutz S. Improving the catalytic activity of Candida antarctica lipase B by circular permutation. Journal of the American Chemical Society. 127: 13466-7. PMID 16190688 DOI: 10.1021/Ja053932H  0.607
2004 Gerth ML, Patrick WM, Lutz S. A second-generation system for unbiased reading frame selection. Protein Engineering, Design & Selection : Peds. 17: 595-602. PMID 15331775 DOI: 10.1093/Protein/Gzh068  0.697
2004 Lutz S, Patrick WM. Novel methods for directed evolution of enzymes: quality, not quantity. Current Opinion in Biotechnology. 15: 291-7. PMID 15296927 DOI: 10.1016/J.Copbio.2004.05.004  0.33
2004 Sismour AM, Lutz S, Park JH, Lutz MJ, Boyer PL, Hughes SH, Benner SA. PCR amplification of DNA containing non-standard base pairs by variants of reverse transcriptase from Human Immunodeficiency Virus-1. Nucleic Acids Research. 32: 728-35. PMID 14757837 DOI: 10.1093/Nar/Gkh241  0.756
2004 Lutz S. Engineering lipase B from Candida antarctica Tetrahedron Asymmetry. 15: 2743-2748. DOI: 10.1016/J.Tetasy.2004.06.031  0.328
2003 Lee SG, Lutz S, Benkovic SJ. On the structural and functional modularity of glycinamide ribonucleotide formyltransferases. Protein Science : a Publication of the Protein Society. 12: 2206-14. PMID 14500878 DOI: 10.1110/Ps.03139603  0.561
2003 Lutz S, Ostermeier M. Preparation of SCRATCHY hybrid protein libraries: size- and in-frame selection of nucleic acid sequences. Methods in Molecular Biology (Clifton, N.J.). 231: 143-51. PMID 12824611 DOI: 10.1385/1-59259-395-X:143  0.304
2002 Lutz S, Fast W, Benkovic SJ. A universal, vector-based system for nucleic acid reading-frame selection. Protein Engineering. 15: 1025-30. PMID 12601143 DOI: 10.1093/Protein/15.12.1025  0.69
2002 Rajagopalan PT, Lutz S, Benkovic SJ. Coupling interactions of distal residues enhance dihydrofolate reductase catalysis: mutational effects on hydride transfer rates. Biochemistry. 41: 12618-28. PMID 12379104 DOI: 10.1021/Bi026369D  0.48
2001 Lutz S, Ostermeier M, Moore GL, Maranas CD, Benkovic SJ. Creating multiple-crossover DNA libraries independent of sequence identity. Proceedings of the National Academy of Sciences of the United States of America. 98: 11248-53. PMID 11562494 DOI: 10.1073/Pnas.201413698  0.519
2001 Stevenson JD, Lutz S, Benkovic SJ. Retracing Enzyme Evolution in the (betaalpha)(8)-Barrel Scaffold. Angewandte Chemie (International Ed. in English). 40: 1854-1856. PMID 11385654 DOI: 10.1002/1521-3773(20010518)40:10<1854::Aid-Anie1854>3.0.Co;2-F  0.519
2001 Moore GL, Maranas CD, Lutz S, Benkovic SJ. Predicting crossover generation in DNA shuffling. Proceedings of the National Academy of Sciences of the United States of America. 98: 3226-31. PMID 11248060 DOI: 10.1073/Pnas.051631498  0.461
2001 Lutz S, Ostermeier M, Benkovic SJ. Rapid generation of incremental truncation libraries for protein engineering using alpha-phosphothioate nucleotides. Nucleic Acids Research. 29: E16. PMID 11160936 DOI: 10.1093/Nar/29.4.E16  0.541
2001 Stevenson JD, Lutz S, Benkovic SJ. Auf der Spur der Evolution von einem als Gerüst in Enzymen dienenden (βα)8-Fass Angewandte Chemie. 113: 1906-1908. DOI: 10.1002/1521-3757(20010518)113:10<1906::Aid-Ange1906>3.0.Co;2-9  0.381
2000 Lutz S, Benkovic SJ. Homology-independent protein engineering. Current Opinion in Biotechnology. 11: 319-24. PMID 10975450 DOI: 10.1016/S0958-1669(00)00106-3  0.505
1999 Lutz S, Burgstaller P, Benner SA. An in vitro screening technique for DNA polymerases that can incorporate modified nucleotides. Pseudo-thymidine as a substrate for thermostable polymerases. Nucleic Acids Research. 27: 2792-8. PMID 10373598 DOI: 10.1093/Nar/27.13.2792  0.536
1999 Lutz S, Benner SA. Simple one-pot synthesis of a 2'-tritium labeled C-deoxynucleoside. Bioorganic & Medicinal Chemistry Letters. 9: 723-6. PMID 10201836 DOI: 10.1016/S0960-894X(99)00068-2  0.47
1998 Benner SA, Battersby TR, Eschgfaller B, Hutter D, Kodra JT, Lutz S, Arslan T, Baschlin DK, Blattler M, Egli M, Hammer C, Held HA, Horlacher J, Huang Z, Hyrup B, et al. Redesigning nucleic acids. Pure and Applied Chemistry. Chimie Pure Et Appliquã©E. 70: 263-6. PMID 11542721 DOI: 10.1351/Pac199870020263  0.732
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