Stephen Tomlinson - Publications

Affiliations: 
Immunology Medical University of South Carolina, Charleston, SC, United States 

88 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Nguyen H, Alawieh A, Bastian D, Kuril S, Dai M, Daenthanasanmak A, Zhang M, Iamsawat S, Schutt SD, Wu Y, Sleiman MM, Shetty A, Atkinson C, Sun S, Varela JC, ... Tomlinson S, et al. Targeting the Complement Alternative Pathway Permits Graft Versus Leukemia Activity while Preventing Graft Versus Host Disease. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31919135 DOI: 10.1158/1078-0432.CCR-19-1717  0.68
2019 Zhong F, Hu Z, Jiang K, Lei B, Wu Z, Yuan G, Luo H, Dong C, Tang B, Zheng C, Yang S, Zeng Y, Guo Z, Yu S, Su H, ... ... Tomlinson S, et al. Complement C3 activation regulates the production of tRNA-derived fragments Gly-tRFs and promotes alcohol-induced liver injury and steatosis. Cell Research. PMID 31076642 DOI: 10.1038/s41422-019-0175-2  0.44
2019 Parsons N, Annamalai B, Obert E, Schnabolk G, Tomlinson S, Rohrer B. Inhibition of the alternative complement pathway accelerates repair processes in the murine model of choroidal neovascularization. Molecular Immunology. 108: 8-12. PMID 30763805 DOI: 10.1016/j.molimm.2019.02.001  0.8
2019 Tang B, Tian Y, Liao Y, Li Z, Yu S, Su H, Zhong F, Yuan G, Wang Y, Yu H, Tomlinson S, Qiu X, He S. CBX8 exhibits oncogenic properties and serves as a prognostic factor in hepatocellular carcinoma. Cell Death & Disease. 10: 52. PMID 30718464 DOI: 10.1038/s41419-018-1288-0  0.44
2018 Nguyen H, Kuril S, Bastian D, Kim J, Zhang M, Vaena SG, Dany M, Dai M, Heinrichs JL, Daenthanasanmak A, Iamsawat S, Schutt S, Fu J, Wu Y, Fairlie DP, ... ... Tomlinson S, et al. Complement C3a and C5a receptors promote GVHD by suppressing mitophagy in recipient dendritic cells. Jci Insight. 3. PMID 30568037 DOI: 10.1172/jci.insight.121697  0.68
2018 Scholpa NE, Williams H, Wang W, Corum D, Narang A, Tomlinson S, Sulllivan PG, Rabchevsky AG, Schnellmann RG. Pharmacological stimulation of mitochondrial biogenesis using the FDA-approved β2-adrenoreceptor agonist formoterol for the treatment of spinal cord injury. Journal of Neurotrauma. PMID 30280980 DOI: 10.1089/neu.2018.5669  0.32
2018 Tomlinson S, Thurman JM. Tissue-targeted complement therapeutics. Molecular Immunology. 102: 120-128. PMID 30220307 DOI: 10.1016/j.molimm.2018.06.005  0.56
2018 Mulligan JK, Patel K, Williamson T, Reaves N, Carroll W, Stephenson SE, Gao P, Drake RR, Neely BA, Tomlinson S, Schlosser RJ, Atkinson C. C3a receptor antagonism as a novel therapeutic target for chronic rhinosinusitis. Mucosal Immunology. PMID 29907871 DOI: 10.1038/s41385-018-0048-x  0.68
2018 Schnabolk G, Parsons N, Obert E, Annamalai B, Nasarre C, Tomlinson S, Lewin AS, Rohrer B. Delivery of CR2-fH Using AAV Vector Therapy as Treatment Strategy in the Mouse Model of Choroidal Neovascularization. Molecular Therapy. Methods & Clinical Development. 9: 1-11. PMID 29234687 DOI: 10.1016/j.omtm.2017.11.003  0.8
2017 Marshall K, Jin J, Atkinson C, Alawieh A, Qiao F, Lei B, Chavin KD, He S, Tomlinson S. Natural IgM initiates an inflammatory response important for both hepatic ischemia reperfusion injury and regeneration. Hepatology (Baltimore, Md.). PMID 28880403 DOI: 10.1002/hep.29512  0.68
2017 Narang A, Qiao F, Atkinson C, Zhu H, Yang X, Kulik L, Holers VM, Tomlinson S. Natural IgM antibodies that bind neoepitopes exposed as a result of spinal cord injury , drive secondary injury by activating complement. Journal of Neuroinflammation. 14: 120. PMID 28629465 DOI: 10.1186/s12974-017-0894-6  0.68
2017 Schnabolk G, Beon MK, Tomlinson S, Rohrer B. New Insights on Complement Inhibitor CD59 in Mouse Laser-Induced Choroidal Neovascularization: Mislocalization After Injury and Targeted Delivery for Protein Replacement. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. PMID 28333572 DOI: 10.1089/jop.2016.0101  0.8
2017 Long X, Cheng Q, Liang H, Zhao J, Wang J, Wang W, Tomlinson S, Chen L, Atkinson C, Zhang B, Chen X, Zhu P. Memory CD4(+) T cells are suppressed by CD8(+) regulatory T cells in vitro and in vivo. American Journal of Translational Research. 9: 63-78. PMID 28123634  0.68
2016 Zhu P, Bailey SR, Lei B, Paulos CM, Atkinson C, Tomlinson S. Targeted complement inhibition protects vascularized composite allografts from acute graft injury and prolongs graft survival when combined with subtherapeutic cyclosporine A therapy. Transplantation. PMID 28045880 DOI: 10.1097/TP.0000000000001625  0.68
2016 Tang B, Qi G, Tang F, Yuan S, Wang Z, Liang X, Li B, Yu S, Liu J, Huang Q, Wei Y, Zhai R, Lei B, Yu H, Tomlinson S, et al. Aberrant JMJD3 expression upregulates Slug to promote migration, invasion and stem cell-like behaviors in hepatocellular carcinoma. Cancer Research. PMID 27651311 DOI: 10.1158/0008-5472.CAN-15-3029  0.44
2016 Alawieh A, Wang W, Narang A, Tomlinson S. Thromboembolic Model of Cerebral Ischemia and Reperfusion in Mice. Methods in Molecular Biology (Clifton, N.J.). 1462: 357-72. PMID 27604728 DOI: 10.1007/978-1-4939-3816-2_20  0.32
2016 Holers VM, Tomlinson S, Kulik L, Atkinson C, Rohrer B, Banda N, Thurman JM. New therapeutic and diagnostic opportunities for injured tissue-specific targeting of complement inhibitors and imaging modalities. Seminars in Immunology. PMID 27282113 DOI: 10.1016/j.smim.2016.05.007  0.8
2016 Woodell A, Jones BW, Williamson T, Schnabolk G, Tomlinson S, Atkinson C, Rohrer B. A Targeted Inhibitor of the Alternative Complement Pathway Accelerates Recovery From Smoke-Induced Ocular Injury. Investigative Ophthalmology & Visual Science. 57: 1728-37. PMID 27064393 DOI: 10.1167/iovs.15-18471  0.8
2015 Alawieh A, Elvington A, Zhu H, Yu J, Kindy MS, Atkinson C, Tomlinson S. Modulation of post-stroke degenerative and regenerative processes and subacute protection by site-targeted inhibition of the alternative pathway of complement. Journal of Neuroinflammation. 12: 247. PMID 26714866 DOI: 10.1186/s12974-015-0464-8  0.64
2015 Alawieh A, Narang A, Tomlinson S. Complementing regeneration. Oncotarget. 6: 21769-70. PMID 26318041 DOI: 10.18632/oncotarget.4844  0.32
2015 Alawieh A, Sabra Z, Sabra M, Tomlinson S, Zaraket FA. A Rich-Club Organization in Brain Ischemia Protein Interaction Network. Scientific Reports. 5: 13513. PMID 26310627 DOI: 10.1038/srep13513  0.64
2015 Alawieh A, Sabra M, Sabra Z, Tomlinson S, Zaraket FA. Molecular Architecture of Spinal Cord Injury Protein Interaction Network. Plos One. 10: e0135024. PMID 26241741 DOI: 10.1371/journal.pone.0135024  0.64
2015 Gelber SE, Brent E, Redecha P, Perino G, Tomlinson S, Davisson RL, Salmon JE. Prevention of Defective Placentation and Pregnancy Loss by Blocking Innate Immune Pathways in a Syngeneic Model of Placental Insufficiency. Journal of Immunology (Baltimore, Md. : 1950). 195: 1129-38. PMID 26071558 DOI: 10.4049/jimmunol.1402220  0.64
2015 Varela JC, Tomlinson S. Complement: an overview for the clinician. Hematology/Oncology Clinics of North America. 29: 409-27. PMID 26043382 DOI: 10.1016/j.hoc.2015.02.001  0.64
2015 Cheng Q, He SQ, Gao D, Lei B, Long X, Liang HF, Zhu P, Jin JF, Tang B, Tomlinson S, Wu ZY, Chen XP. Early Application of Auxiliary Partial Orthotopic Liver Transplantation in Murine Model of Wilson Disease. Transplantation. PMID 26018347 DOI: 10.1097/TP.0000000000000787  0.4
2015 Tang B, Tang F, Li B, Yuan S, Xu Q, Tomlinson S, Jin J, Hu W, He S. High USP22 expression indicates poor prognosis in hepatocellular carcinoma. Oncotarget. 6: 12654-67. PMID 25909224  0.44
2015 Atkinson C, Qiao F, Yang X, Zhu P, Reaves N, Kulik L, Goddard M, Holers VM, Tomlinson S. Targeting pathogenic postischemic self-recognition by natural IgM to protect against posttransplantation cardiac reperfusion injury. Circulation. 131: 1171-80. PMID 25825397 DOI: 10.1161/CIRCULATIONAHA.114.010482  0.64
2015 Kulik L, Hewitt FB, Willis VC, Rodriguez R, Tomlinson S, Holers VM. A new mouse anti-mouse complement receptor type 2 and 1 (CR2/CR1) monoclonal antibody as a tool to study receptor involvement in chronic models of immune responses and disease. Molecular Immunology. 63: 479-88. PMID 25457881 DOI: 10.1016/j.molimm.2014.10.005  0.56
2014 Marshall KM, He S, Zhong Z, Atkinson C, Tomlinson S. Dissecting the complement pathway in hepatic injury and regeneration with a novel protective strategy. The Journal of Experimental Medicine. 211: 1793-805. PMID 25113972 DOI: 10.1084/jem.20131902  0.64
2014 Elvington M, Scheiber M, Yang X, Lyons K, Jacqmin D, Wadsworth C, Marshall D, Vanek K, Tomlinson S. Complement-dependent modulation of antitumor immunity following radiation therapy. Cell Reports. 8: 818-30. PMID 25066124 DOI: 10.1016/j.celrep.2014.06.051  0.64
2014 Schnabolk G, Tomlinson S, Rohrer B. The complement regulatory protein CD59: insights into attenuation of choroidal neovascularization. Advances in Experimental Medicine and Biology. 801: 435-40. PMID 24664728 DOI: 10.1007/978-1-4614-3209-8_55  0.8
2014 Di Paolo NC, Baldwin LK, Irons EE, Papayannopoulou T, Tomlinson S, Shayakhmetov DM. IL-1α and complement cooperate in triggering local neutrophilic inflammation in response to adenovirus and eliminating virus-containing cells. Plos Pathogens. 10: e1004035. PMID 24651866 DOI: 10.1371/journal.ppat.1004035  0.64
2013 Tang B, Li Y, Yuan S, Tomlinson S, He S. Upregulation of the δ opioid receptor in liver cancer promotes liver cancer progression both in vitro and in vivo. International Journal of Oncology. 43: 1281-90. PMID 23903826 DOI: 10.3892/ijo.2013.2046  0.44
2013 Khan MA, Maasch C, Vater A, Klussmann S, Morser J, Leung LL, Atkinson C, Tomlinson S, Heeger PS, Nicolls MR. Targeting complement component 5a promotes vascular integrity and limits airway remodeling. Proceedings of the National Academy of Sciences of the United States of America. 110: 6061-6. PMID 23530212 DOI: 10.1073/pnas.1217991110  0.68
2013 Sun S, Zhao G, Liu C, Wu X, Guo Y, Yu H, Song H, Du L, Jiang S, Guo R, Tomlinson S, Zhou Y. Inhibition of complement activation alleviates acute lung injury induced by highly pathogenic avian influenza H5N1 virus infection. American Journal of Respiratory Cell and Molecular Biology. 49: 221-30. PMID 23526211 DOI: 10.1165/rcmb.2012-0428OC  0.4
2013 Atkinson C, Floerchinger B, Qiao F, Casey S, Williamson T, Moseley E, Stoica S, Goddard M, Ge X, Tullius SG, Tomlinson S. Donor brain death exacerbates complement-dependent ischemia/reperfusion injury in transplanted hearts. Circulation. 127: 1290-9. PMID 23443736 DOI: 10.1161/CIRCULATIONAHA.112.000784  0.68
2013 Holers VM, Rohrer B, Tomlinson S. CR2-mediated targeting of complement inhibitors: bench-to-bedside using a novel strategy for site-specific complement modulation. Advances in Experimental Medicine and Biology. 735: 137-54. PMID 23402024 DOI: 10.1007/978-1-4614-4118-2_9  0.64
2012 Qiu S, Liu N, Jia L, Yang G, Su W, Li J, Song L, Yang C, Wang J, Zhang C, Wang Z, Qiao F, Tomlinson S, Atkinson C, Sun Y, et al. A new treatment for neurogenic inflammation caused by EV71 with CR2-targeted complement inhibitor. Virology Journal. 9: 285. PMID 23173749 DOI: 10.1186/1743-422X-9-285  0.68
2012 Hu X, Tomlinson S, Barnum SR. Targeted inhibition of complement using complement receptor 2-conjugated inhibitors attenuates EAE. Neuroscience Letters. 531: 35-9. PMID 23079547 DOI: 10.1016/j.neulet.2012.10.012  0.64
2012 Elvington A, Atkinson C, Zhu H, Yu J, Takahashi K, Stahl GL, Kindy MS, Tomlinson S. The alternative complement pathway propagates inflammation and injury in murine ischemic stroke. Journal of Immunology (Baltimore, Md. : 1950). 189: 4640-7. PMID 23028050 DOI: 10.4049/jimmunol.1201904  0.64
2012 Zhu Q, Lin L, Cheng Q, Xu Q, Zhang J, Tomlinson S, Jin J, Chen X, He S. The role of acid sphingomyelinase and caspase 5 in hypoxia-induced HuR cleavage and subsequent apoptosis in hepatocytes. Biochimica Et Biophysica Acta. 1821: 1453-61. PMID 22906436 DOI: 10.1016/j.bbalip.2012.08.005  0.44
2012 Ramos TN, Darley MM, Weckbach S, Stahel PF, Tomlinson S, Barnum SR. The C5 convertase is not required for activation of the terminal complement pathway in murine experimental cerebral malaria. The Journal of Biological Chemistry. 287: 24734-8. PMID 22689574 DOI: 10.1074/jbc.C112.378364  0.64
2012 Schepp-Berglind J, Atkinson C, Elvington M, Qiao F, Mannon P, Tomlinson S. Complement-dependent injury and protection in a murine model of acute dextran sulfate sodium-induced colitis. Journal of Immunology (Baltimore, Md. : 1950). 188: 6309-18. PMID 22566568 DOI: 10.4049/jimmunol.1200553  0.64
2012 Elvington M, Huang Y, Morgan BP, Qiao F, van Rooijen N, Atkinson C, Tomlinson S. A targeted complement-dependent strategy to improve the outcome of mAb therapy, and characterization in a murine model of metastatic cancer. Blood. 119: 6043-51. PMID 22442351 DOI: 10.1182/blood-2011-10-383232  0.68
2012 Elvington A, Atkinson C, Kulik L, Zhu H, Yu J, Kindy MS, Holers VM, Tomlinson S. Pathogenic natural antibodies propagate cerebral injury following ischemic stroke in mice. Journal of Immunology (Baltimore, Md. : 1950). 188: 1460-8. PMID 22198950 DOI: 10.4049/jimmunol.1102132  0.64
2012 Takeda K, Thurman JM, Tomlinson S, Okamoto M, Shiraishi Y, Ferreira VP, Cortes C, Pangburn MK, Holers VM, Gelfand EW. The critical role of complement alternative pathway regulator factor H in allergen-induced airway hyperresponsiveness and inflammation. Journal of Immunology (Baltimore, Md. : 1950). 188: 661-7. PMID 22174452 DOI: 10.4049/jimmunol.1101813  0.8
2011 Sun S, Guo Y, Zhao G, Zhou X, Li J, Hu J, Yu H, Chen Y, Song H, Qiao F, Xu G, Yang F, Wu Y, Tomlinson S, Duan Z, et al. Complement and the alternative pathway play an important role in LPS/D-GalN-induced fulminant hepatic failure. Plos One. 6: e26838. PMID 22069473 DOI: 10.1371/journal.pone.0026838  0.44
2011 Sekine H, Ruiz P, Gilkeson GS, Tomlinson S. The dual role of complement in the progression of renal disease in NZB/W F(1) mice and alternative pathway inhibition. Molecular Immunology. 49: 317-23. PMID 22000720 DOI: 10.1016/j.molimm.2011.09.015  0.4
2011 Khan MA, Jiang X, Dhillon G, Beilke J, Holers VM, Atkinson C, Tomlinson S, Nicolls MR. CD4+ T cells and complement independently mediate graft ischemia in the rejection of mouse orthotopic tracheal transplants. Circulation Research. 109: 1290-301. PMID 21998328 DOI: 10.1161/CIRCRESAHA.111.250167  0.64
2011 Renner B, Ferreira VP, Cortes C, Goldberg R, Ljubanovic D, Pangburn MK, Pickering MC, Tomlinson S, Holland-Neidermyer A, Strassheim D, Holers VM, Thurman JM. Binding of factor H to tubular epithelial cells limits interstitial complement activation in ischemic injury. Kidney International. 80: 165-73. PMID 21544060 DOI: 10.1038/ki.2011.115  0.8
2011 Zhang Z, Knoepp SM, Ku H, Sansbury HM, Xie Y, Chahal MS, Tomlinson S, Meier KE. Differential expression of FAK and Pyk2 in metastatic and non-metastatic EL4 lymphoma cell lines. Clinical & Experimental Metastasis. 28: 551-65. PMID 21533871 DOI: 10.1007/s10585-011-9391-y  0.64
2011 Wickham SE, Hotze EM, Farrand AJ, Polekhina G, Nero TL, Tomlinson S, Parker MW, Tweten RK. Mapping the intermedilysin-human CD59 receptor interface reveals a deep correspondence with the binding site on CD59 for complement binding proteins C8alpha and C9. The Journal of Biological Chemistry. 286: 20952-62. PMID 21507937 DOI: 10.1074/jbc.M111.237446  0.64
2011 Sekine H, Kinser TT, Qiao F, Martinez E, Paulling E, Ruiz P, Gilkeson GS, Tomlinson S. The benefit of targeted and selective inhibition of the alternative complement pathway for modulating autoimmunity and renal disease in MRL/lpr mice. Arthritis and Rheumatism. 63: 1076-85. PMID 21452327 DOI: 10.1002/art.30222  0.44
2011 Sun S, Wang H, Zhao G, An Y, Guo Y, Du L, Song H, Qiao F, Yu H, Wu X, Atkinson C, Jiang S, Tomlinson S, Zhou Y. Complement inhibition alleviates paraquat-induced acute lung injury. American Journal of Respiratory Cell and Molecular Biology. 45: 834-42. PMID 21421909 DOI: 10.1165/rcmb.2010-0444OC  0.68
2011 Rohrer B, Coughlin B, Kunchithapautham K, Long Q, Tomlinson S, Takahashi K, Holers VM. The alternative pathway is required, but not alone sufficient, for retinal pathology in mouse laser-induced choroidal neovascularization. Molecular Immunology. 48: e1-8. PMID 21257205 DOI: 10.1016/j.molimm.2010.12.016  0.64
2011 Qing X, Redecha PB, Burmeister MA, Tomlinson S, D'Agati VD, Davisson RL, Salmon JE. Targeted inhibition of complement activation prevents features of preeclampsia in mice. Kidney International. 79: 331-9. PMID 20944547 DOI: 10.1038/ki.2010.393  0.64
2011 Hylton DJ, Hoffman SM, Van Rooijen N, Tomlinson S, Fleming SD. Macrophage-produced IL-12p70 mediates hemorrhage-induced damage in a complement-dependent manner. Shock (Augusta, Ga.). 35: 134-40. PMID 20577145 DOI: 10.1097/SHK.0b013e3181ed8ec9  0.64
2010 Atkinson C, He S, Morris K, Qiao F, Casey S, Goddard M, Tomlinson S. Targeted complement inhibitors protect against posttransplant cardiac ischemia and reperfusion injury and reveal an important role for the alternative pathway of complement activation. Journal of Immunology (Baltimore, Md. : 1950). 185: 7007-13. PMID 20962256 DOI: 10.4049/jimmunol.1001504  0.68
2010 Qiao F, Atkinson C, Kindy MS, Shunmugavel A, Morgan BP, Song H, Tomlinson S. The alternative and terminal pathways of complement mediate post-traumatic spinal cord inflammation and injury. The American Journal of Pathology. 177: 3061-70. PMID 20952585 DOI: 10.2353/ajpath.2010.100158  0.64
2010 Pope MR, Hoffman SM, Tomlinson S, Fleming SD. Complement regulates TLR4-mediated inflammatory responses during intestinal ischemia reperfusion. Molecular Immunology. 48: 356-64. PMID 20800895 DOI: 10.1016/j.molimm.2010.07.004  0.64
2010 Rohrer B, Long Q, Coughlin B, Renner B, Huang Y, Kunchithapautham K, Ferreira VP, Pangburn MK, Gilkeson GS, Thurman JM, Tomlinson S, Holers VM. A targeted inhibitor of the complement alternative pathway reduces RPE injury and angiogenesis in models of age-related macular degeneration. Advances in Experimental Medicine and Biology. 703: 137-49. PMID 20711712 DOI: 10.1007/978-1-4419-5635-4_10  0.8
2010 Jia L, Xu Y, Zhang C, Wang Y, Chong H, Qiu S, Wang L, Zhong Y, Liu W, Sun Y, Qiao F, Tomlinson S, Song H, Zhou Y, He Y. A novel trifunctional IgG-like bispecific antibody to inhibit HIV-1 infection and enhance lysis of HIV by targeting activation of complement. Virology Journal. 7: 142. PMID 20584336 DOI: 10.1186/1743-422X-7-142  0.44
2010 Zhang C, Xu Y, Jia L, Yang Y, Wang Y, Sun Y, Huang L, Qiao F, Tomlinson S, Liu X, Zhou Y, Song H. A new therapeutic strategy for lung tissue injury induced by influenza with CR2 targeting complement inhibitor. Virology Journal. 7: 30. PMID 20144216 DOI: 10.1186/1743-422X-7-30  0.44
2010 He S, Atkinson C, Qiao F, Chen X, Tomlinson S. Ketamine-xylazine-acepromazine compared with isoflurane for anesthesia during liver transplantation in rodents. Journal of the American Association For Laboratory Animal Science : Jaalas. 49: 45-51. PMID 20122316  0.68
2009 Banda NK, Levitt B, Glogowska MJ, Thurman JM, Takahashi K, Stahl GL, Tomlinson S, Arend WP, Holers VM. Targeted inhibition of the complement alternative pathway with complement receptor 2 and factor H attenuates collagen antibody-induced arthritis in mice. Journal of Immunology (Baltimore, Md. : 1950). 183: 5928-37. PMID 19828624 DOI: 10.4049/jimmunol.0901826  0.8
2009 Atkinson C, Varela JC, Tomlinson S. Complement-dependent inflammation and injury in a murine model of brain dead donor hearts. Circulation Research. 105: 1094-101. PMID 19815824 DOI: 10.1161/CIRCRESAHA.109.194977  0.68
2009 He S, Atkinson C, Evans Z, Ellett JD, Southwood M, Elvington A, Chavin KD, Tomlinson S. A role for complement in the enhanced susceptibility of steatotic livers to ischemia and reperfusion injury. Journal of Immunology (Baltimore, Md. : 1950). 183: 4764-72. PMID 19752222 DOI: 10.4049/jimmunol.0900550  0.68
2009 He S, Atkinson C, Qiao F, Cianflone K, Chen X, Tomlinson S. A complement-dependent balance between hepatic ischemia/reperfusion injury and liver regeneration in mice. The Journal of Clinical Investigation. 119: 2304-16. PMID 19620784 DOI: 10.1172/JCI38289  0.68
2009 Thurman JM, Renner B, Kunchithapautham K, Ferreira VP, Pangburn MK, Ablonczy Z, Tomlinson S, Holers VM, Rohrer B. Oxidative stress renders retinal pigment epithelial cells susceptible to complement-mediated injury. The Journal of Biological Chemistry. 284: 16939-47. PMID 19386604 DOI: 10.1074/jbc.M808166200  0.64
2009 Rohrer B, Long Q, Coughlin B, Wilson RB, Huang Y, Qiao F, Tang PH, Kunchithapautham K, Gilkeson GS, Tomlinson S. A targeted inhibitor of the alternative complement pathway reduces angiogenesis in a mouse model of age-related macular degeneration. Investigative Ophthalmology & Visual Science. 50: 3056-64. PMID 19264882 DOI: 10.1167/iovs.08-2222  0.8
2009 Stano P, Williams V, Villani M, Cymbalyuk ES, Qureshi A, Huang Y, Morace G, Luberto C, Tomlinson S, Del Poeta M. App1: an antiphagocytic protein that binds to complement receptors 3 and 2. Journal of Immunology (Baltimore, Md. : 1950). 182: 84-91. PMID 19109138  0.32
2008 Huang Y, Qiao F, Atkinson C, Holers VM, Tomlinson S. A novel targeted inhibitor of the alternative pathway of complement and its therapeutic application in ischemia/reperfusion injury. Journal of Immunology (Baltimore, Md. : 1950). 181: 8068-76. PMID 19017999  0.64
2008 Varela JC, Imai M, Atkinson C, Ohta R, Rapisardo M, Tomlinson S. Modulation of protective T cell immunity by complement inhibitor expression on tumor cells. Cancer Research. 68: 6734-42. PMID 18701498 DOI: 10.1158/0008-5472.CAN-08-0502  0.68
2008 Varela JC, Atkinson C, Woolson R, Keane TE, Tomlinson S. Upregulated expression of complement inhibitory proteins on bladder cancer cells and anti-MUC1 antibody immune selection. International Journal of Cancer. 123: 1357-63. PMID 18561323 DOI: 10.1002/ijc.23676  0.68
2008 Knoepp SM, Chahal MS, Xie Y, Zhang Z, Brauner DJ, Hallman MA, Robinson SA, Han S, Imai M, Tomlinson S, Meier KE. Effects of active and inactive phospholipase D2 on signal transduction, adhesion, migration, invasion, and metastasis in EL4 lymphoma cells. Molecular Pharmacology. 74: 574-84. PMID 18523140 DOI: 10.1124/mol.107.040105  0.64
2008 Atkinson C, Qiao F, Song H, Gilkeson GS, Tomlinson S. Low-dose targeted complement inhibition protects against renal disease and other manifestations of autoimmune disease in MRL/lpr mice. Journal of Immunology (Baltimore, Md. : 1950). 180: 1231-8. PMID 18178863  0.68
2007 Song H, Qiao F, Atkinson C, Holers VM, Tomlinson S. A complement C3 inhibitor specifically targeted to sites of complement activation effectively ameliorates collagen-induced arthritis in DBA/1J mice. Journal of Immunology (Baltimore, Md. : 1950). 179: 7860-7. PMID 18025232  0.64
2007 Imai M, Ohta R, Varela JC, Song H, Tomlinson S. Enhancement of antibody-dependent mechanisms of tumor cell lysis by a targeted activator of complement. Cancer Research. 67: 9535-41. PMID 17909064 DOI: 10.1158/0008-5472.CAN-07-1690  0.68
2007 Huang Y, Fedarovich A, Tomlinson S, Davies C. Crystal structure of CD59: implications for molecular recognition of the complement proteins C8 and C9 in the membrane-attack complex. Acta Crystallographica. Section D, Biological Crystallography. 63: 714-21. PMID 17505110 DOI: 10.1107/S0907444907015557  0.32
2006 Atkinson C, Zhu H, Qiao F, Varela JC, Yu J, Song H, Kindy MS, Tomlinson S. Complement-dependent P-selectin expression and injury following ischemic stroke. Journal of Immunology (Baltimore, Md. : 1950). 177: 7266-74. PMID 17082645  0.64
2006 Qiao F, Atkinson C, Song H, Pannu R, Singh I, Tomlinson S. Complement plays an important role in spinal cord injury and represents a therapeutic target for improving recovery following trauma. The American Journal of Pathology. 169: 1039-47. PMID 16936276 DOI: 10.2353/ajpath.2006.060248  0.68
2006 Huang Y, Qiao F, Abagyan R, Hazard S, Tomlinson S. Defining the CD59-C9 binding interaction. The Journal of Biological Chemistry. 281: 27398-404. PMID 16844690 DOI: 10.1074/jbc.M603690200  0.44
2005 Imai M, Landen C, Ohta R, Cheung NK, Tomlinson S. Complement-mediated mechanisms in anti-GD2 monoclonal antibody therapy of murine metastatic cancer. Cancer Research. 65: 10562-8. PMID 16288049 DOI: 10.1158/0008-5472.CAN-05-1894  0.44
2005 Atkinson C, Song H, Lu B, Qiao F, Burns TA, Holers VM, Tsokos GC, Tomlinson S. Targeted complement inhibition by C3d recognition ameliorates tissue injury without apparent increase in susceptibility to infection. The Journal of Clinical Investigation. 115: 2444-53. PMID 16127466 DOI: 10.1172/JCI25208  0.68
2005 Huang Y, Smith CA, Song H, Morgan BP, Abagyan R, Tomlinson S. Insights into the human CD59 complement binding interface toward engineering new therapeutics. The Journal of Biological Chemistry. 280: 34073-9. PMID 16079145 DOI: 10.1074/jbc.M504922200  0.4
2005 He C, Imai M, Song H, Quigg RJ, Tomlinson S. Complement inhibitors targeted to the proximal tubule prevent injury in experimental nephrotic syndrome and demonstrate a key role for C5b-9. Journal of Immunology (Baltimore, Md. : 1950). 174: 5750-7. PMID 15843577  0.44
2004 Ohta R, Kondor N, Dohi N, Tomlinson S, Imai M, Holers VM, Okada H, Okada N. Mouse complement receptor-related gene y/p65-neutralized tumor vaccine induces antitumor activity in vivo. Journal of Immunology (Baltimore, Md. : 1950). 173: 205-13. PMID 15210776  0.64
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