| Year |
Citation |
Score |
| 2023 |
Heath SL, Horne WS, Lengyel GA. Effects of chirality and side chain length in C-dialkylated residues on β-hairpin peptide folded structure and stability. Organic & Biomolecular Chemistry. 21: 6320-6324. PMID 37503895 DOI: 10.1039/d3ob00963g |
0.804 |
|
| 2023 |
Harmon TW, Horne WS. Protein Backbone Alteration in Non-hairpin β-Turns: Impacts on Tertiary Folded Structure and Folded Stability. Chembiochem : a European Journal of Chemical Biology. e202300113. PMID 36920327 DOI: 10.1002/cbic.202300113 |
0.67 |
|
| 2022 |
Rao SR, Harmon TW, Heath SL, Wolfe JA, Santhouse JR, O'Brien GL, Distefano AN, Reinert ZE, Horne WS. Chemical Shifts of Artificial Monomers Used to Construct Heterogeneous-Backbone Protein Mimetics in Random Coil and Folded States. Peptide Science (Hoboken, N.J.). 115. PMID 37397503 DOI: 10.1002/pep2.24297 |
0.303 |
|
| 2022 |
Cabalteja CC, Lin Q, Harmon TW, Rao SR, Di YP, Horne WS. Heterogeneous-Backbone Proteomimetic Analogues of Lasiocepsin, a Disulfide-Rich Antimicrobial Peptide with a Compact Tertiary Fold. Acs Chemical Biology. PMID 35290019 DOI: 10.1021/acschembio.2c00138 |
0.362 |
|
| 2021 |
Matsubara T, Addison WN, Kokabu S, Neff L, Horne W, Gori F, Baron R. Characterization of unique functionalities in c-Src domains required for osteoclast podosome belt formation. The Journal of Biological Chemistry. 100790. PMID 34019873 DOI: 10.1016/j.jbc.2021.100790 |
0.574 |
|
| 2021 |
Camiolo MJ, Zhou X, Oriss TB, Yan Q, Gorry M, Horne W, Trudeau JB, Scholl K, Chen W, Kolls JK, Ray P, Weisel FJ, Weisel NM, Aghaeepour N, Nadeau K, et al. High-dimensional profiling clusters asthma severity by lymphoid and non-lymphoid status. Cell Reports. 35: 108974. PMID 33852838 DOI: 10.1016/j.celrep.2021.108974 |
0.556 |
|
| 2021 |
Priedigkeit N, Ding K, Horne W, Kolls JK, Du T, Lucas PC, Blohmer JU, Denkert C, Machleidt A, Ingold-Heppner B, Oesterreich S, Lee AV. Acquired mutations and transcriptional remodeling in long-term estrogen-deprived locoregional breast cancer recurrences. Breast Cancer Research : Bcr. 23: 1. PMID 33407744 DOI: 10.1186/s13058-020-01379-3 |
0.548 |
|
| 2020 |
Rao SR, Horne WS. Proteomimetic Zinc Finger Domains with Modified Metal-binding β-Turns. Peptide Science (Hoboken, N.J.). 112. PMID 33733039 DOI: 10.1002/Pep2.24177 |
0.394 |
|
| 2020 |
So J, Ningappa M, Glessner J, Min J, Ashokkumar C, Ranganathan S, Higgs BW, Li D, Sun Q, Schmitt L, Biery AC, Dobrowolski S, Trautz C, Fuhrman L, Schwartz MC, ... ... Horne W, et al. Biliary-Atresia-Associated Mannosidase-1-Alpha-2 Gene Regulates Biliary and Ciliary Morphogenesis and Laterality. Frontiers in Physiology. 11: 538701. PMID 33192543 DOI: 10.3389/fphys.2020.538701 |
0.561 |
|
| 2020 |
Zhang Y, Chandra V, Riquelme Sanchez E, Dutta P, Quesada PR, Rakoski A, Zoltan M, Arora N, Baydogan S, Horne W, Burks J, Xu H, Hussain P, Wang H, Gupta S, et al. Interleukin-17-induced neutrophil extracellular traps mediate resistance to checkpoint blockade in pancreatic cancer. The Journal of Experimental Medicine. 217. PMID 32860704 DOI: 10.1084/jem.20190354 |
0.561 |
|
| 2020 |
Bogetti AT, Piston HE, Leung JMG, Cabalteja CC, Yang DT, DeGrave AJ, Debiec KT, Cerutti DS, Case DA, Horne WS, Chong LT. A twist in the road less traveled: The AMBER ff15ipq-m force field for protein mimetics The Journal of Chemical Physics. 153: 064101. DOI: 10.1063/5.0019054 |
0.353 |
|
| 2020 |
Horne WS, Grossmann TN. Proteomimetics as protein-inspired scaffolds with defined tertiary folding patterns Nature Chemistry. 12: 331-337. DOI: 10.1038/S41557-020-0420-9 |
0.371 |
|
| 2019 |
Henkel M, Partyka J, Gregory AD, Forno E, Cho MH, Eddens T, Tout AR, Salamacha N, Horne W, Rao KS, Wu Y, Alcorn JF, Kostka D, Hirsch R, Celedón JC, et al. Follistatin-like 1 Attenuation Causes Spontaneous Smoke-Resistant Pulmonary Emphysema. American Journal of Respiratory and Critical Care Medicine. PMID 31834999 DOI: 10.1164/Rccm.201905-0973Oc |
0.546 |
|
| 2019 |
Shaikh N, Martin JM, Hoberman A, Skae M, Milkovich L, McElheny C, Hickey RW, Gabriel LV, Kearney DH, Majd M, Shalaby-Rana E, Tseng G, Kolls J, Horne W, Huo Z, et al. Biomarkers that differentiate false positive urinalyses from true urinary tract infection. Pediatric Nephrology (Berlin, Germany). PMID 31758242 DOI: 10.1007/s00467-019-04403-7 |
0.552 |
|
| 2019 |
Castillo-Dela Cruz P, Wanek AG, Kumar P, An X, Elsegeiny W, Horne W, Fitch A, Burr AHP, Gopalakrishna KP, Chen K, Methé BA, Canna SW, Hand TW, Kolls JK. Intestinal IL-17R Signaling Constrains IL-18-Driven Liver Inflammation by the Regulation of Microbiome-Derived Products. Cell Reports. 29: 2270-2283.e7. PMID 31747600 DOI: 10.1016/J.Celrep.2019.10.042 |
0.558 |
|
| 2019 |
Werner HM, Estabrooks SK, Preston GM, Brodsky JL, Horne WS. Exploring the Functional Consequences of Protein Backbone Alteration in Ubiquitin through Native Chemical Ligation. Chembiochem : a European Journal of Chemical Biology. PMID 31059184 DOI: 10.1002/Cbic.201900225 |
0.357 |
|
| 2019 |
Shaikh N, Martin JM, Hoberman A, Skae M, Milkovich L, Nowalk A, McElheny C, Hickey RW, Kearney D, Majd M, Shalaby-Rana E, Tseng G, Alcorn JF, Kolls J, Kurs-Lasky M, ... ... Horne W, et al. Host and Bacterial Markers that Differ in Children with Cystitis and Pyelonephritis. The Journal of Pediatrics. PMID 30905425 DOI: 10.1016/j.jpeds.2019.01.012 |
0.545 |
|
| 2019 |
Cabalteja CC, Mihalko DS, Horne WS. Heterogeneous-Backbone Foldamer Mimics of a Computationally Designed, Disulfide-Rich Miniprotein. Chembiochem : a European Journal of Chemical Biology. 20: 103-110. PMID 30326175 DOI: 10.1002/Cbic.201800558 |
0.468 |
|
| 2018 |
Elsegeiny W, Zheng M, Eddens T, Gallo RL, Dai G, Trevejo-Nunez G, Castillo P, Kracinovsky K, Cleveland H, Horne W, Franks J, Pociask D, Pilarski M, Alcorn JF, Chen K, et al. Murine models of Pneumocystis infection recapitulate human primary immune disorders. Jci Insight. 3. PMID 29925696 DOI: 10.1172/Jci.Insight.91894 |
0.587 |
|
| 2018 |
George KL, Horne WS. Foldamer Tertiary Structure through Sequence-Guided Protein Backbone Alteration. Accounts of Chemical Research. PMID 29672021 DOI: 10.1021/Acs.Accounts.8B00048 |
0.426 |
|
| 2018 |
Zhang Y, Zoltan M, Riquelme E, Xu H, Sahin I, Castro-Pando S, Montiel MF, Chang K, Jiang Z, Ling J, Gupta S, Horne W, Pruski M, Wang H, Sun SC, et al. Immune Cell Production of Interleukin 17 Induces Stem Cell Features of Pancreatic Intraepithelial Neoplasia Cells. Gastroenterology. PMID 29604293 DOI: 10.1053/J.Gastro.2018.03.041 |
0.552 |
|
| 2017 |
Marvin CW, Grimm HM, Miller NC, Horne WS, Hutchison GR. Interplay Among Sequence, Folding Propensity, and Bio-Piezoelectric Response in Short Peptides and Peptoids. The Journal of Physical Chemistry. B. PMID 29035526 DOI: 10.1021/Acs.Jpcb.7B10085 |
0.422 |
|
| 2017 |
Domingo-Gonzalez R, Das S, Griffiths KL, Ahmed M, Bambouskova M, Gopal R, Gondi S, Muñoz-Torrico M, Salazar-Lezama MA, Cruz-Lagunas A, Jiménez-Álvarez L, Ramirez-Martinez G, Espinosa-Soto R, Sultana T, Lyons-Weiler J, ... ... Horne W, et al. Interleukin-17 limits hypoxia-inducible factor 1α and development of hypoxic granulomas during tuberculosis. Jci Insight. 2. PMID 28978810 DOI: 10.1172/Jci.Insight.92973 |
0.564 |
|
| 2017 |
Priedigkeit N, Watters RJ, Lucas PC, Basudan A, Bhargava R, Horne W, Kolls JK, Fang Z, Rosenzweig MQ, Brufsky AM, Weiss KR, Oesterreich S, Lee AV. Exome-capture RNA sequencing of decade-old breast cancers and matched decalcified bone metastases. Jci Insight. 2. PMID 28878133 DOI: 10.1172/Jci.Insight.95703 |
0.557 |
|
| 2017 |
Zhang Q, Chikina M, Szymczak-Workman AL, Horne W, Kolls JK, Vignali KM, Normolle D, Bettini M, Workman CJ, Vignali DAA. LAG3 limits regulatory T cell proliferation and function in autoimmune diabetes. Science Immunology. 2. PMID 28783703 DOI: 10.1126/Sciimmunol.Aah4569 |
0.557 |
|
| 2017 |
Walters CR, Szantai-Kis DM, Zhang Y, Reinert ZE, Horne WS, Chenoweth DM, Petersson EJ. The effects of thioamide backbone substitution on protein stability: a study in α-helical, β-sheet, and polyproline II helical contexts. Chemical Science. 8: 2868-2877. PMID 28553525 DOI: 10.1039/C6Sc05580J |
0.644 |
|
| 2017 |
Overacre-Delgoffe AE, Chikina M, Dadey RE, Yano H, Brunazzi EA, Shayan G, Horne W, Moskovitz JM, Kolls JK, Sander C, Shuai Y, Normolle DP, Kirkwood JM, Ferris RL, Delgoffe GM, et al. Interferon-γ Drives Treg Fragility to Promote Anti-tumor Immunity. Cell. PMID 28552348 DOI: 10.1016/J.Cell.2017.05.005 |
0.552 |
|
| 2017 |
George KL, Horne WS. Heterogeneous-Backbone Foldamer Mimics of Zinc Finger Tertiary Structure. Journal of the American Chemical Society. PMID 28509549 DOI: 10.1021/Jacs.7B03114 |
0.415 |
|
| 2017 |
Campfield BT, Eddens T, Henkel M, Majewski M, Horne W, Chaly Y, Gaffen SL, Hirsch R, Kolls JK. Follistatin-like protein 1 modulates IL-17 signaling via IL-17RC regulation in stromal cells. Immunology and Cell Biology. PMID 28377613 DOI: 10.1038/Icb.2017.26 |
0.57 |
|
| 2017 |
Matmor M, Lengyel GA, Horne WS, Ashkenasy N. Peptide-functionalized semiconductor surfaces: strong surface electronic effects from minor alterations to backbone composition. Physical Chemistry Chemical Physics : Pccp. 19: 5709-5714. PMID 28191555 DOI: 10.1039/C6Cp07198H |
0.798 |
|
| 2017 |
Tavenor NA, Murnin MJ, Horne WS. Supramolecular Metal-Coordination Polymers, Nets, and Frameworks from Synthetic Coiled-Coil Peptides. Journal of the American Chemical Society. 139: 2212-2215. PMID 28161945 DOI: 10.1021/Jacs.7B00651 |
0.393 |
|
| 2016 |
Griffiths KL, Ahmed M, Das S, Gopal R, Horne W, Connell TD, Moynihan KD, Kolls JK, Irvine DJ, Artyomov MN, Rangel-Moreno J, Khader SA. Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy. Nature Communications. 7: 13894. PMID 28004802 DOI: 10.1038/Ncomms13894 |
0.546 |
|
| 2016 |
Kar K, Baker MA, Lengyel GA, Hoop CL, Kodali R, Byeon IJ, Horne WS, van der Wel PC, Wetzel R. Backbone engineering within a latent β-hairpin structure to design inhibitors of polyglutamine amyloid formation. Journal of Molecular Biology. PMID 27986569 DOI: 10.1016/J.Jmb.2016.12.010 |
0.81 |
|
| 2016 |
Ramani K, Garg AV, Jawale CV, Conti HR, Whibley N, Jackson EK, Shiva SS, Horne W, Kolls JK, Gaffen SL, Biswas PS. The Kallikrein-Kinin System: A Novel Mediator of IL-17-Driven Anti-Candida Immunity in the Kidney. Plos Pathogens. 12: e1005952. PMID 27814401 DOI: 10.1371/Journal.Ppat.1005952 |
0.558 |
|
| 2016 |
Karnes MA, Schettler SL, Werner HM, Kurz AF, Horne WS, Lengyel GA. Thermodynamic and Structural Impact of α,α-Dialkylated Residue Incorporation in a β-Hairpin Peptide. Organic Letters. PMID 27436716 DOI: 10.1021/Acs.Orglett.6B01936 |
0.804 |
|
| 2016 |
Eddens T, Campfield BT, Serody K, Manni ML, Horne W, Elsegeiny W, McHugh KJ, Pociask D, Chen K, Zheng M, Alcorn JF, Wenzel S, Kolls JK. A Novel CD4(+) T-cell Dependent Murine Model of Pneumocystis Driven Asthma-like Pathology. American Journal of Respiratory and Critical Care Medicine. PMID 27007260 DOI: 10.1164/Rccm.201511-2205Oc |
0.555 |
|
| 2016 |
Haney CM, Werner HM, McKay JJ, Horne WS. Thermodynamic origin of α-helix stabilization by side-chain cross-links in a small protein. Organic & Biomolecular Chemistry. PMID 27006192 DOI: 10.1039/C6Ob00475J |
0.814 |
|
| 2016 |
Kumar P, Monin L, Castillo P, Elsegeiny W, Horne W, Eddens T, Vikram A, Good M, Schoenborn AA, Bibby K, Montelaro RC, Metzger DW, Gulati AS, Kolls JK. Intestinal Interleukin-17 Receptor Signaling Mediates Reciprocal Control of the Gut Microbiota and Autoimmune Inflammation. Immunity. 44: 659-671. PMID 26982366 DOI: 10.1016/J.Immuni.2016.02.007 |
0.563 |
|
| 2016 |
Cunningham TF, Pornsuwan S, Horne WS, Saxena S. Rotameric preferences of a protein spin label at edge-strand β-sheet sites. Protein Science : a Publication of the Protein Society. PMID 26948069 DOI: 10.1002/Pro.2918 |
0.661 |
|
| 2016 |
Tavenor NA, Reinert ZE, Lengyel GA, Griffith BD, Horne WS. Comparison of design strategies for α-helix backbone modification in a protein tertiary fold. Chemical Communications (Cambridge, England). 52: 3789-92. PMID 26853882 DOI: 10.1039/C6Cc00273K |
0.81 |
|
| 2016 |
Zheng M, Horne W, McAleer JP, Pociask D, Eddens T, Good M, Gao B, Kolls JK. Therapeutic Role of Interleukin 22 in experimental intra-abdominal Klebsiella pneumoniae infection in mice. Infection and Immunity. PMID 26729763 DOI: 10.1128/IAI.01268-15 |
0.563 |
|
| 2016 |
Werner HM, Cabalteja CC, Horne WS. Inside Cover: Peptide Backbone Composition and Protease Susceptibility: Impact of Modification Type, Position, and Tandem Substitution (ChemBioChem 8/2016) Chembiochem. 17: 643-643. DOI: 10.1002/Cbic.201600145 |
0.4 |
|
| 2015 |
Horne WS. Foldamers: Biomimetic and built to order. Nature Chemistry. 7: 858-9. PMID 26492002 DOI: 10.1038/Nchem.2385 |
0.653 |
|
| 2015 |
Ray M, Horne W, McAleer JP, Ricks DM, Kreindler JL, Fitzsimons MS, Chan PP, Trevejo-Nunez G, Chen K, Fajt M, Chen W, Ray A, Wenzel S, Kolls JK. RNA-seq in Pulmonary Medicine: How Much Is Enough? American Journal of Respiratory and Critical Care Medicine. 192: 389-91. PMID 26230238 DOI: 10.1164/Rccm.201403-0475Le |
0.539 |
|
| 2015 |
Werner HM, Cabalteja CC, Horne WS. Peptide Backbone Composition and Protease Susceptibility: Impact of Modification Type, Position, and Tandem Substitution. Chembiochem : a European Journal of Chemical Biology. PMID 26205791 DOI: 10.1002/Cbic.201500312 |
0.73 |
|
| 2015 |
Werner HM, Horne WS. Folding and function in α/β-peptides: targets and therapeutic applications. Current Opinion in Chemical Biology. 28: 75-82. PMID 26136051 DOI: 10.1016/J.Cbpa.2015.06.013 |
0.724 |
|
| 2015 |
Eddens T, Elsegeiny W, Nelson MP, Horne W, Campfield BT, Steele C, Kolls JK. Eosinophils Contribute to Early Clearance of Pneumocystis murina Infection. Journal of Immunology (Baltimore, Md. : 1950). 195: 185-93. PMID 25994969 DOI: 10.4049/Jimmunol.1403162 |
0.564 |
|
| 2015 |
Cunningham TF, Putterman MR, Desai A, Horne WS, Saxena S. The double-histidine Cu²⁺-binding motif: a highly rigid, site-specific spin probe for electron spin resonance distance measurements. Angewandte Chemie (International Ed. in English). 54: 6330-4. PMID 25821033 DOI: 10.1002/Anie.201501968 |
0.632 |
|
| 2015 |
Haney CM, Horne WS. Receptor-templated stapling of intrinsically disordered peptide ligands. Organic & Biomolecular Chemistry. 13: 4183-9. PMID 25758597 DOI: 10.1039/C5Ob00269A |
0.795 |
|
| 2015 |
Werner HM, Horne WS. Folding and function in α/β-peptides: Targets and therapeutic applications Current Opinion in Chemical Biology. 28: 75-82. DOI: 10.1016/j.cbpa.2015.06.013 |
0.3 |
|
| 2014 |
Reinert ZE, Horne WS. Protein backbone engineering as a strategy to advance foldamers toward the frontier of protein-like tertiary structure. Organic & Biomolecular Chemistry. 12: 8796-802. PMID 25285575 DOI: 10.1039/C4Ob01769B |
0.676 |
|
| 2014 |
Reinert ZE, Horne WS. Folding Thermodynamics of Protein-Like Oligomers with Heterogeneous Backbones. Chemical Science (Royal Society of Chemistry : 2010). 5: 3325-3330. PMID 25071931 DOI: 10.1039/C4Sc01094A |
0.673 |
|
| 2014 |
Tavenor NA, Silva KI, Saxena S, Horne WS. Origins of structural flexibility in protein-based supramolecular polymers revealed by DEER spectroscopy. The Journal of Physical Chemistry. B. 118: 9881-9. PMID 25060334 DOI: 10.1021/Jp505643W |
0.657 |
|
| 2014 |
Lengyel GA, Reinert ZE, Griffith BD, Horne WS. Comparison of backbone modification in protein β-sheets by α→γ residue replacement and α-residue methylation. Organic & Biomolecular Chemistry. 12: 5375-81. PMID 24909436 DOI: 10.1039/C4Ob00886C |
0.821 |
|
| 2014 |
Oshaben KM, Horne WS. Tuning assembly size in Peptide-based supramolecular polymers by modulation of subunit association affinity. Biomacromolecules. 15: 1436-42. PMID 24598042 DOI: 10.1021/bm5000423 |
0.684 |
|
| 2014 |
Haney CM, Horne WS. Dynamic covalent side-chain cross-links via intermolecular oxime or hydrazone formation from bifunctional peptides and simple organic linkers. Journal of Peptide Science : An Official Publication of the European Peptide Society. 20: 108-14. PMID 24402694 DOI: 10.1002/Psc.2596 |
0.814 |
|
| 2014 |
Biosse Duplan M, Zalli D, Stephens S, Zenger S, Neff L, Oelkers JM, Lai FP, Horne W, Rottner K, Baron R. Microtubule dynamic instability controls podosome patterning in osteoclasts through EB1, cortactin, and Src. Molecular and Cellular Biology. 34: 16-29. PMID 24144981 DOI: 10.1128/Mcb.00578-13 |
0.565 |
|
| 2013 |
Reinert ZE, Lengyel GA, Horne WS. Protein-like tertiary folding behavior from heterogeneous backbones. Journal of the American Chemical Society. 135: 12528-31. PMID 23937097 DOI: 10.1021/Ja405422V |
0.81 |
|
| 2013 |
Haney CM, Horne WS. Oxime side-chain cross-links in an α-helical coiled-coil protein: structure, thermodynamics, and folding-templated synthesis of bicyclic species. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 11342-51. PMID 23843311 DOI: 10.1002/Chem.201300506 |
0.83 |
|
| 2013 |
Lengyel GA, Eddinger GA, Horne WS. Introduction of cyclically constrained γ-residues stabilizes an α-peptide hairpin in aqueous solution. Organic Letters. 15: 944-7. PMID 23390979 DOI: 10.1021/Ol4001125 |
0.825 |
|
| 2013 |
Kar K, Hoop CL, Drombosky KW, Baker MA, Kodali R, Arduini I, van der Wel PC, Horne WS, Wetzel R. β-hairpin-mediated nucleation of polyglutamine amyloid formation. Journal of Molecular Biology. 425: 1183-97. PMID 23353826 DOI: 10.1016/J.Jmb.2013.01.016 |
0.683 |
|
| 2012 |
Oshaben KM, Salari R, McCaslin DR, Chong LT, Horne WS. The native GCN4 leucine-zipper domain does not uniquely specify a dimeric oligomerization state. Biochemistry. 51: 9581-91. PMID 23116373 DOI: 10.1021/Bi301132K |
0.675 |
|
| 2012 |
Lengyel GA, Horne WS. Design strategies for the sequence-based mimicry of side-chain display in protein β-sheets by α/β-peptides. Journal of the American Chemical Society. 134: 15906-13. PMID 22946450 DOI: 10.1021/Ja306311R |
0.831 |
|
| 2012 |
Cunningham TF, McGoff MS, Sengupta I, Jaroniec CP, Horne WS, Saxena S. High-resolution structure of a protein spin-label in a solvent-exposed β-sheet and comparison with DEER spectroscopy. Biochemistry. 51: 6350-9. PMID 22809334 DOI: 10.1021/Bi300328W |
0.647 |
|
| 2012 |
Reinert ZE, Musselman ED, Elcock AH, Horne WS. A PEG-based oligomer as a backbone replacement for surface-exposed loops in a protein tertiary structure. Chembiochem : a European Journal of Chemical Biology. 13: 1107-11. PMID 22539233 DOI: 10.1002/Cbic.201200200 |
0.676 |
|
| 2012 |
Johnson LM, Mortenson DE, Yun HG, Horne WS, Ketas TJ, Lu M, Moore JP, Gellman SH. Enhancement of α-helix mimicry by an α/β-peptide foldamer via incorporation of a dense ionic side-chain array. Journal of the American Chemical Society. 134: 7317-20. PMID 22524614 DOI: 10.1021/Ja302428D |
0.825 |
|
| 2012 |
Boersma MD, Haase HS, Peterson-Kaufman KJ, Lee EF, Clarke OB, Colman PM, Smith BJ, Horne WS, Fairlie WD, Gellman SH. Evaluation of diverse α/β-backbone patterns for functional α-helix mimicry: analogues of the Bim BH3 domain. Journal of the American Chemical Society. 134: 315-23. PMID 22040025 DOI: 10.1021/Ja207148M |
0.806 |
|
| 2012 |
Johnson LM, Mortenson DE, Yun HG, Horne WS, Ketas TJ, Lu M, Moore JP, Gellman SH. Enhancement of alpha-helix mimicry by an alpha / beta-peptide foldamer via incorporation of a dense ionic side-chain array. Journal of the American Chemical Society. 134: 7317-7320. DOI: 10.2210/Pdb4Dzv/Pdb |
0.803 |
|
| 2012 |
Staples JK, Oshaben KM, Horne WS. A modular synthetic platform for the construction of protein-based supramolecular polymers via coiled-coil self-assembly Chemical Science. 3: 3387. DOI: 10.1039/C2Sc20729J |
0.382 |
|
| 2011 |
Horne WS. Peptide and peptoid foldamers in medicinal chemistry. Expert Opinion On Drug Discovery. 6: 1247-62. PMID 22647064 DOI: 10.1517/17460441.2011.632002 |
0.693 |
|
| 2011 |
Wan S, Wu F, Rech JC, Green ME, Balachandran R, Horne WS, Day BW, Floreancig PE. Total synthesis and biological evaluation of pederin, psymberin, and highly potent analogs. Journal of the American Chemical Society. 133: 16668-79. PMID 21902245 DOI: 10.1021/Ja207331M |
0.639 |
|
| 2011 |
Lee EF, Smith BJ, Horne WS, Mayer KN, Evangelista M, Colman PM, Gellman SH, Fairlie WD. Structural basis of Bcl-xL recognition by a BH3-mimetic α/β-peptide generated by sequence-based design. Chembiochem : a European Journal of Chemical Biology. 12: 2025-32. PMID 21744457 DOI: 10.1002/Cbic.201100314 |
0.786 |
|
| 2011 |
Haney CM, Loch MT, Horne WS. Promoting peptide α-helix formation with dynamic covalent oxime side-chain cross-links. Chemical Communications (Cambridge, England). 47: 10915-7. PMID 21691623 DOI: 10.1039/C1Cc12010G |
0.822 |
|
| 2011 |
Johnson LM, Horne WS, Gellman SH. Broad distribution of energetically important contacts across an extended protein interface. Journal of the American Chemical Society. 133: 10038-41. PMID 21644542 DOI: 10.1021/Ja203358T |
0.773 |
|
| 2011 |
Lengyel GA, Frank RC, Horne WS. Hairpin folding behavior of mixed α/β-peptides in aqueous solution. Journal of the American Chemical Society. 133: 4246-9. PMID 21370877 DOI: 10.1021/Ja2002346 |
0.818 |
|
| 2011 |
Boersma MD, Haase HS, Peterson-Kaufman KJ, Lee EF, Clarke OB, Colman PM, Smith BJ, Horne WS, Fairlie WD, Gellman SH. Evaluation of Diverse Alpha/Beta-Backbone Patterns for Functional Alpha-Helix Mimicry: Analogues of the Bim Bh3 Domain. Journal of the American Chemical Society. 134: 315. DOI: 10.2210/Pdb4A1U/Pdb |
0.761 |
|
| 2011 |
Lee EF, Smith BJ, Horne WS, Mayer KN, Evangelista M, Colman PM, Gellman SH, Fairlie WD. Cover Picture: Structural Basis of Bcl-xL Recognition by a BH3-Mimetic α/β-Peptide Generated by Sequence-Based Design (ChemBioChem 13/2011) Chembiochem. 12: 1941-1941. DOI: 10.1002/Cbic.201190058 |
0.598 |
|
| 2010 |
Price JL, Horne WS, Gellman SH. Structural consequences of beta-amino acid preorganization in a self-assembling alpha/beta-peptide: fundamental studies of foldameric helix bundles. Journal of the American Chemical Society. 132: 12378-87. PMID 20718422 DOI: 10.1021/Ja103543S |
0.793 |
|
| 2009 |
Salazar V, Dewey CW, Schwark W, Badgley BL, Gleed RD, Horne W, Ludders JW. Pharmacokinetics of single-dose oral pregabalin administration in normal dogs Veterinary Anaesthesia and Analgesia. 36: 574-580. PMID 19845930 DOI: 10.1111/j.1467-2995.2009.00486.x |
0.54 |
|
| 2009 |
Horne WS, Johnson LM, Ketas TJ, Klasse PJ, Lu M, Moore JP, Gellman SH. Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers. Proceedings of the National Academy of Sciences of the United States of America. 106: 14751-6. PMID 19706443 DOI: 10.1073/Pnas.0902663106 |
0.791 |
|
| 2009 |
Giuliano MW, Horne WS, Gellman SH. An alpha/beta-peptide helix bundle with a pure beta3-amino acid core and a distinctive quaternary structure. Journal of the American Chemical Society. 131: 9860-1. PMID 19580264 DOI: 10.1021/Ja8099294 |
0.825 |
|
| 2009 |
Horne WS, Olsen CA, Beierle JM, Montero A, Ghadiri MR. Probing the bioactive conformation of an archetypal natural product HDAC inhibitor with conformationally homogeneous triazole-modified cyclic tetrapeptides. Angewandte Chemie (International Ed. in English). 48: 4718-24. PMID 19267380 DOI: 10.1002/Anie.200805900 |
0.78 |
|
| 2009 |
Beierle JM, Horne WS, van Maarseveen JH, Waser B, Reubi JC, Ghadiri MR. Conformationally homogeneous heterocyclic pseudotetrapeptides as three-dimensional scaffolds for rational drug design: receptor-selective somatostatin analogues. Angewandte Chemie (International Ed. in English). 48: 4725-9. PMID 19266506 DOI: 10.1002/Anie.200805901 |
0.721 |
|
| 2008 |
Horne WS, Gellman SH. Foldamers with heterogeneous backbones. Accounts of Chemical Research. 41: 1399-408. PMID 18590282 DOI: 10.1021/Ar800009N |
0.779 |
|
| 2008 |
Horne WS, Price JL, Gellman SH. Interplay among side chain sequence, backbone composition, and residue rigidification in polypeptide folding and assembly. Proceedings of the National Academy of Sciences of the United States of America. 105: 9151-6. PMID 18587049 DOI: 10.1073/Pnas.0801135105 |
0.805 |
|
| 2008 |
Horne WS, Boersma MD, Windsor MA, Gellman SH. Sequence-based design of alpha/beta-peptide foldamers that mimic BH3 domains. Angewandte Chemie (International Ed. in English). 47: 2853-6. PMID 18330876 DOI: 10.1002/Anie.200705315 |
0.784 |
|
| 2007 |
Price JL, Horne WS, Gellman SH. Discrete heterogeneous quaternary structure formed by alpha/beta-peptide foldamers and alpha-peptides. Journal of the American Chemical Society. 129: 6376-7. PMID 17465552 DOI: 10.1021/Ja071203R |
0.821 |
|
| 2007 |
Chi Y, English EP, Pomerantz WC, Horne WS, Joyce LA, Alexander LR, Fleming WS, Hopkins EA, Gellman SH. Practical synthesis of enantiomerically pure beta2-amino acids via proline-catalyzed diastereoselective aminomethylation of aldehydes. Journal of the American Chemical Society. 129: 6050-5. PMID 17439122 DOI: 10.1021/Ja070063I |
0.769 |
|
| 2007 |
Horne WS, Price JL, Keck JL, Gellman SH. Helix bundle quaternary structure from alpha/beta-peptide foldamers. Journal of the American Chemical Society. 129: 4178-80. PMID 17362016 DOI: 10.1021/Ja070396F |
0.822 |
|
| 2006 |
Ashkenasy N, Horne WS, Ghadiri MR. Design of self-assembling peptide nanotubes with delocalized electronic states. Small (Weinheim An Der Bergstrasse, Germany). 2: 99-102. PMID 17193563 DOI: 10.1002/Smll.200500252 |
0.745 |
|
| 2006 |
Ashkenasy N, Horne WS, Ghadiri M. Cover Picture: Design of Self-Assembling Peptide Nanotubes with Delocalized Electronic States (Small 1/2006) Small. 2: 1-1. DOI: 10.1002/Smll.200690000 |
0.561 |
|
| 2005 |
van Maarseveen JH, Horne WS, Ghadiri MR. Efficient route to C2 symmetric heterocyclic backbone modified cyclic peptides. Organic Letters. 7: 4503-6. PMID 16178569 DOI: 10.1021/ol0518028 |
0.726 |
|
| 2005 |
Horne WS, Wiethoff CM, Cui C, Wilcoxen KM, Amorin M, Ghadiri MR, Nemerow GR. Antiviral cyclic D,L-alpha-peptides: targeting a general biochemical pathway in virus infections. Bioorganic & Medicinal Chemistry. 13: 5145-53. PMID 15993611 DOI: 10.1016/J.Bmc.2005.05.051 |
0.794 |
|
| 2005 |
Horne WS, Ashkenasy N, Ghadiri MR. Modulating charge transfer through cyclic D,L-alpha-peptide self-assembly. Chemistry (Weinheim An Der Bergstrasse, Germany). 11: 1137-44. PMID 15624124 DOI: 10.1002/Chem.200400923 |
0.754 |
|
| 2004 |
Horne WS, Yadav MK, Stout CD, Ghadiri MR. Heterocyclic peptide backbone modifications in an alpha-helical coiled coil. Journal of the American Chemical Society. 126: 15366-7. PMID 15563148 DOI: 10.1021/Ja0450408 |
0.782 |
|
| 2004 |
Whittier CA, Horne W, Slenning B, Loomis M, Stoskopf MK. Comparison of storage methods for reverse-transcriptase PCR amplification of rotavirus RNA from gorilla (Gorilla g. gorilla) fecal samples. Journal of Virological Methods. 116: 11-7. PMID 14715302 DOI: 10.1016/J.Jviromet.2003.10.003 |
0.563 |
|
| 2003 |
Horne WS, Stout CD, Ghadiri MR. A heterocyclic peptide nanotube. Journal of the American Chemical Society. 125: 9372-6. PMID 12889966 DOI: 10.1021/Ja034358H |
0.775 |
|
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