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Ryan A. Shenvi, Ph.D. - Publications

Affiliations: 
Chemistry Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Organic synthesis, Total synthesis, Natural products
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55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ting SI, Snelson DW, Huffman TR, Kuroo A, Sato R, Shenvi RA. Synthesis of (-)-Cotylenol, a 14-3-3 Molecular Glue Component. Journal of the American Chemical Society. 145: 20634-20645. PMID 37683289 DOI: 10.1021/jacs.3c07849  0.35
2021 Huffman BJ, Chu T, Hanaki Y, Wong J, Chen S, Houk K, Shenvi RA. Stereodivergent Attached-Ring Synthesis via Non-Covalent Interactions: A Short Formal Synthesis of Merrilactone A. Angewandte Chemie (International Ed. in English). PMID 34820990 DOI: 10.1002/anie.202114514  0.342
2020 Hill SJ, Brion AUCM, Shenvi RA. Chemical syntheses of the salvinorin chemotype of KOR agonist. Natural Product Reports. PMID 32808003 DOI: 10.1039/D0Np00028K  0.391
2020 Crossley SWM, Tong G, Lambrecht MJ, Burdge HE, Shenvi RA. Synthesis of (-)-Picrotoxinin by Late-Stage Strong Bond Activation. Journal of the American Chemical Society. 142: 11376-11381. PMID 32573211 DOI: 10.1021/Jacs.0C05042  0.341
2020 Matos J, Green S, Chun Y, Dang V, Dushin R, Richardson P, Chen J, Piotrowski D, Paegel B, Shenvi RA. Cycloisomerization of olefins in water. Angewandte Chemie (International Ed. in English). PMID 32285542 DOI: 10.1002/Ange.202003948  0.384
2020 Huffman BJ, Chen S, Schwarz JL, Plata RE, Chin EN, Lairson LL, Houk KN, Shenvi RA. Electronic complementarity permits hindered butenolide heterodimerization and discovery of novel cGAS/STING pathway antagonists. Nature Chemistry. PMID 32042135 DOI: 10.1038/S41557-019-0413-8  0.399
2019 Martinez RM, Burdge HE, Shenvi RA. Reanalysis of Lindenatriene, a Building Block for the Synthesis of Lindenane Oligomers. Tetrahedron. 75: 3140-3144. PMID 31896888 DOI: 10.1016/J.Tet.2019.03.011  0.4
2019 Baker MA, Demoret RM, Ohtawa M, Shenvi RA. Concise asymmetric synthesis of (-)-bilobalide. Nature. PMID 31618759 DOI: 10.1038/S41586-019-1690-5  0.393
2019 Flood DT, Asai S, Zhang X, Wang J, Yoon L, Adams ZC, Dillingham BC, Sanchez BB, Vantourout JC, Flanagan ME, Piotrowski DW, Richardson PF, Green SA, Shenvi RA, Chen JS, et al. Expanding Reactivity in DNA-Encoded Library Synthesis via Reversible Binding of DNA to an Inert Quaternary Ammonium Support. Journal of the American Chemical Society. PMID 31136164 DOI: 10.1021/Jacs.9B03774  0.668
2019 Green SA, Huffman TR, McCourt RO, van der Puyl V, Shenvi RA. Hydroalkylation of Olefins To Form Quaternary Carbons. Journal of the American Chemical Society. PMID 31030508 DOI: 10.1021/Jacs.9B02844  0.309
2019 Huffman T, Wu Y, Emmerich A, Shenvi RA. Intermolecular Heck Coupling with Hindered Alkenes Directed by Potassium Carboxylates. Angewandte Chemie (International Ed. in English). PMID 30602064 DOI: 10.1002/Anie.201813233  0.39
2018 Matos JLM, Vásquez Céspedes S, Gu J, Oguma T, Shenvi RA. Branch-Selective Addition of Unactivated Olefins into Imines and Aldehydes. Journal of the American Chemical Society. PMID 30463404 DOI: 10.1021/Jacs.8B11699  0.323
2018 Green SA, Crossley SWM, Matos JLM, Vásquez-Céspedes S, Shevick SL, Shenvi RA. The High Chemofidelity of Metal-Catalyzed Hydrogen Atom Transfer. Accounts of Chemical Research. PMID 30406655 DOI: 10.1021/Acs.Accounts.8B00337  0.388
2018 Shevick SL, Obradors C, Shenvi RA. Mechanistic Interrogation of Co/Ni-Dual Catalyzed Hydroarylation. Journal of the American Chemical Society. PMID 30153002 DOI: 10.1021/Jacs.8B06458  0.398
2018 Green SA, Vásquez-Céspedes S, Shenvi RA. Iron-Nickel Dual-Catalysis: A New Engine for Olefin Functionalization and the Formation of Quaternary Centers. Journal of the American Chemical Society. PMID 30048124 DOI: 10.1021/Jacs.8B05868  0.371
2018 Witkin JM, Shenvi RA, Li X, Gleason SD, Weiss J, Morrow D, Catow JT, Wakulchik M, Ohtawa M, Lu HH, Martinez MD, Schkeryantz JM, Carpenter TS, Lightstone FC, Cerne R. Pharmacological characterization of the neurotrophic sesquiterpene jiadifenolide reveals a non-convulsant signature and potential for progression in neurodegenerative disease studies. Biochemical Pharmacology. PMID 29940173 DOI: 10.1016/J.Bcp.2018.06.022  0.707
2018 Lambrecht MJ, Kelly JW, Shenvi RA. Mechanism of Action of the Cytotoxic Asmarine Alkaloids. Acs Chemical Biology. PMID 29653046 DOI: 10.1021/Acschembio.8B00096  0.321
2017 Roach JJ, Sasano Y, Schmid CL, Zaidi S, Katritch V, Stevens RC, Bohn LM, Shenvi RA. Dynamic Strategic Bond Analysis Yields a Ten-Step Synthesis of 20-nor-Salvinorin A, a Potent κ-OR Agonist. Acs Central Science. 3: 1329-1336. PMID 29296674 DOI: 10.1021/Acscentsci.7B00488  0.406
2017 Ohtawa M, Krambis MJ, Cerne R, Schkeryantz JM, Witkin J, Shenvi RA. Synthesis of (-)-11-O-Debenzoyltashironin: Neurotrophic Sesquiterpenes Cause Hyperexcitation. Journal of the American Chemical Society. PMID 28644021 DOI: 10.1021/Jacs.7B04206  0.309
2017 Reiher CA, Shenvi RA. Stereocontrolled Synthesis of Kalihinol C. Journal of the American Chemical Society. PMID 28252949 DOI: 10.1021/Jacs.7B01124  0.4
2016 Green SA, Melendez-Matos JL, Yagi A, Shenvi RA. Branch-Selective Hydroarylation: Iodoarene-Olefin Cross Coupling. Journal of the American Chemical Society. PMID 27623023 DOI: 10.1021/Jacs.6B08507  0.326
2016 Crossley SW, Obradors C, Martinez RM, Shenvi RA. Mn-, Fe-, and Co-Catalyzed Radical Hydrofunctionalizations of Olefins. Chemical Reviews. PMID 27461578 DOI: 10.1021/Acs.Chemrev.6B00334  0.358
2016 Tada N, Jansen DJ, Mower MP, Blewett MM, Umotoy JC, Cravatt BF, Wolan DW, Shenvi RA. Synthesis and Sulfur Electrophilicity of the Nuphar Thiaspirane Pharmacophore. Acs Central Science. 2: 401-8. PMID 27413784 DOI: 10.1021/Acscentsci.6B00113  0.355
2016 Lu HH, Pronin SV, Antonova-Koch Y, Meister S, Winzeler EA, Shenvi RA. Synthesis of (+)-7,20-Diisocyanoadociane and Liver-Stage Antiplasmodial Activity of the Isocyanoterpene Class. Journal of the American Chemical Society. PMID 27244042 DOI: 10.1021/Jacs.6B03899  0.734
2016 Crossley SW, Martinez RM, Guevara-Zuluaga S, Shenvi RA. Synthesis of the Privileged 8-Arylmenthol Class by Radical Arylation of Isopulegol. Organic Letters. PMID 27175746 DOI: 10.1021/Acs.Orglett.6B01047  0.45
2016 Obradors C, Martinez RM, Shenvi RA. Ph(i-PrO)SiH2: An Exceptional Reductant for Metal-Catalyzed Hydrogen Atom Transfers. Discovery and Study. Journal of the American Chemical Society. PMID 26984323 DOI: 10.1021/Jacs.6B02032  0.357
2016 Shenvi RA. Cluster Preface: Reinventing Radical Reactions Synlett. 27: 678-679. DOI: 10.1055/S-0035-1561221  0.312
2016 Shenvi R. Reaction: And You, of Tender Years 1 Chem. 1: 334-335. DOI: 10.1016/J.Chempr.2016.08.015  0.308
2015 Tabor MG, Shenvi RA. Synthesis of Lepadiformine Using a Hydroamination Transform. Organic Letters. PMID 26584132 DOI: 10.1021/Acs.Orglett.5B02992  0.412
2015 Crossley SW, Barabé F, Shenvi RA. Correction to "Simple, Chemoselective, Catalytic Olefin Isomerization". Journal of the American Chemical Society. 137: 13209. PMID 26426732 DOI: 10.1021/Jacs.5B08593  0.321
2015 Crossley SW, Shenvi RA. A Longitudinal Study of Alkaloid Synthesis Reveals Functional Group Interconversions as Bad Actors. Chemical Reviews. 115: 9465-531. PMID 26158529 DOI: 10.1021/Acs.Chemrev.5B00154  0.365
2015 Lu HH, Martinez MD, Shenvi RA. An eight-step gram-scale synthesis of (-)-jiadifenolide. Nature Chemistry. 7: 604-7. PMID 26100810 DOI: 10.1038/Nchem.2283  0.766
2015 Roach JJ, Shenvi RA. Supramolecular catalysis: Terpenes in tight spaces. Nature Chemistry. 7: 187-9. PMID 25698322 DOI: 10.1038/Nchem.2191  0.363
2015 Wan KK, Iwasaki K, Umotoy JC, Wolan DW, Shenvi RA. Nitrosopurines en route to potently cytotoxic asmarines. Angewandte Chemie (International Ed. in English). 54: 2410-5. PMID 25580910 DOI: 10.1002/Anie.201411493  0.357
2015 Schnermann MJ, Shenvi RA. Syntheses and biological studies of marine terpenoids derived from inorganic cyanide. Natural Product Reports. 32: 543-77. PMID 25514696 DOI: 10.1039/C4Np00109E  0.417
2015 Wan KK, Shenvi RA. Conjuring a Supernatural Product – DelMarine Synlett. DOI: 10.1055/S-0035-1561329  0.426
2014 Crossley SW, Barabé F, Shenvi RA. Simple, chemoselective, catalytic olefin isomerization. Journal of the American Chemical Society. 136: 16788-91. PMID 25398144 DOI: 10.1021/Ja5105602  0.336
2014 Jansen DJ, Shenvi RA. Synthesis of medicinally relevant terpenes: reducing the cost and time of drug discovery. Future Medicinal Chemistry. 6: 1127-48. PMID 25078134 DOI: 10.4155/Fmc.14.71  0.366
2013 Pronin SV, Reiher CA, Shenvi RA. Stereoinversion of tertiary alcohols to tertiary-alkyl isonitriles and amines. Nature. 501: 195-9. PMID 24025839 DOI: 10.1038/Nature12472  0.645
2013 Jansen DJ, Shenvi RA. Synthesis of (-)-neothiobinupharidine. Journal of the American Chemical Society. 135: 1209-12. PMID 23298203 DOI: 10.1021/Ja310778T  0.428
2013 Pronin SV, Reiher CA, Shenvi RA. Erratum: Corrigendum: Stereoinversion of tertiary alcohols to tertiary-alkyl isonitriles and amines Nature. 503: 300-300. DOI: 10.1038/Nature12795  0.573
2012 Pronin SV, Shenvi RA. Synthesis of a potent antimalarial amphilectene. Journal of the American Chemical Society. 134: 19604-6. PMID 23153381 DOI: 10.1021/Ja310129B  0.688
2012 Pronin SV, Shenvi RA. Synthesis of highly strained terpenes by non-stop tail-to-head polycyclization. Nature Chemistry. 4: 915-20. PMID 23089866 DOI: 10.1038/Nchem.1458  0.641
2012 Pronin SV, Tabor MG, Jansen DJ, Shenvi RA. A stereoselective hydroamination transform to access polysubstituted indolizidines. Journal of the American Chemical Society. 134: 2012-5. PMID 22263967 DOI: 10.1021/Ja211090N  0.662
2011 Shi J, Manolikakes G, Yeh CH, Guerrero CA, Shenvi RA, Shigehisa H, Baran PS. Scalable synthesis of cortistatin A and related structures. Journal of the American Chemical Society. 133: 8014-27. PMID 21539314 DOI: 10.1021/Ja202103E  0.748
2010 Shenvi RA, Corey EJ. Synthetic access to bent polycycles by cation-pi cyclization. Organic Letters. 12: 3548-51. PMID 20670018 DOI: 10.1021/Ol101410G  0.541
2009 Shi J, Shigehisa H, Guerrero CA, Shenvi RA, Li CC, Baran PS. Stereodivergent synthesis of 17-alpha and 17-beta-alpharyl steroids: application and biological evaluation of D-ring cortistatin analogues. Angewandte Chemie (International Ed. in English). 48: 4328-31. PMID 19434636 DOI: 10.1002/Anie.200901116  0.747
2009 Shenvi RA, Corey EJ. A short and efficient synthesis of (-)-7-methylomuralide, a potent proteasome inhibitor. Journal of the American Chemical Society. 131: 5746-7. PMID 19338298 DOI: 10.1021/Ja901400Q  0.597
2009 Shenvi RA, O'Malley DP, Baran PS. Chemoselectivity: the mother of invention in total synthesis. Accounts of Chemical Research. 42: 530-41. PMID 19182997 DOI: 10.1021/Ar800182R  0.672
2009 Shenvi RA, Corey EJ. Synthesis of (-)-7-Methylomuralide Synfacts. 2009: 1193-1193. DOI: 10.1055/S-0029-1218031  0.625
2008 Shenvi RA, Guerrero CA, Shi J, Li CC, Baran PS. Synthesis of (+)-cortistatin A. Journal of the American Chemical Society. 130: 7241-3. PMID 18479104 DOI: 10.1021/Ja8023466  0.779
2007 Baran P, Shenvi R. Synthesis of (±)-Chartelline C Synfacts. 2007: 0233-0233. DOI: 10.1055/S-2007-968198  0.596
2006 Baran PS, Shenvi RA. Total synthesis of (+/-)-chartelline C. Journal of the American Chemical Society. 128: 14028-9. PMID 17061876 DOI: 10.1021/Ja0659673  0.668
2006 Baran PS, Shenvi RA, Nguyen SA. One-step synthesis of 4,5-disubstituted pyrimidines using commercially available and inexpensive reagents Heterocycles. 70: 581-586. DOI: 10.3987/Com-06-S(W)27  0.653
2005 Baran PS, Shenvi RA, Mitsos CA. A remarkable ring contraction en route to the chartelline alkaloids. Angewandte Chemie (International Ed. in English). 44: 3714-7. PMID 15900528 DOI: 10.1002/Anie.200500522  0.596
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