Ole V Mortensen - Publications

Affiliations: 
Pharmacology & Physiology Drexel University, Philadelphia, PA, United States 

29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Bernstein DL, Lewandowski SI, Besada C, Place D, España RA, Mortensen OV. Inactivation of ERK1/2 Signaling in Dopaminergic Neurons by Map Kinase Phosphatase MKP3 Regulates Dopamine Signaling and Motivation for Cocaine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 44. PMID 38296649 DOI: 10.1523/JNEUROSCI.0727-23.2023  0.779
2023 Aggarwal S, Mortensen OV. Discovery and Development of Monoamine Transporter Ligands. Advances in Neurobiology. 30: 101-129. PMID 36928847 DOI: 10.1007/978-3-031-21054-9_4  0.444
2022 Camicia F, Vaca HR, Guarnaschelli I, Koziol U, Mortensen OV, Fontana ACK. Molecular characterization of the serotonergic transporter from the cestode Echinococcus granulosus: pharmacology and potential role in the nervous system. Parasitology Research. PMID 35169884 DOI: 10.1007/s00436-022-07466-y  0.55
2021 Refai O, Aggarwal S, Cheng MH, Gichi Z, Salvino JM, Bahar I, Blakely RD, Mortensen OV. Allosteric Modulator KM822 Attenuates Behavioral Actions of Amphetamine in C. elegans through Interactions with the Dopamine Transporter DAT-1. Molecular Pharmacology. PMID 34906999 DOI: 10.1124/molpharm.121.000400  0.698
2021 Aggarwal S, Cheng MH, Salvino JM, Bahar I, Mortensen OV. Functional Characterization of the Dopaminergic Psychostimulant Sydnocarb as an Allosteric Modulator of the Human Dopamine Transporter. Biomedicines. 9. PMID 34199621 DOI: 10.3390/biomedicines9060634  0.597
2021 Shaw JK, Pamela Alonso I, Lewandowski SI, Scott MO, O'Connor BM, Aggarwal S, De Biasi M, Mortensen OV, España RA. Individual differences in dopamine uptake in the dorsomedial striatum prior to cocaine exposure predict motivation for cocaine in male rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 33953341 DOI: 10.1038/s41386-021-01009-2  0.77
2020 Brodnik ZD, Xu W, Batra A, Lewandowski SI, Ruiz CM, Mortensen OV, Kortagere S, Mahler SV, España RA. Chemogenetic manipulation of dopamine neurons dictates cocaine potency at distal dopamine transporters. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33046544 DOI: 10.1523/JNEUROSCI.0894-20.2020  0.773
2020 Duffield M, Patel A, Mortensen OV, Schnur D, Gonzalez-Suarez AD, Torres-Salazar D, Fontana ACK. Transport rate of EAAT2 is regulated by amino acid located at the interface between the scaffolding and substrate transport domains. Neurochemistry International. 104792. PMID 32668264 DOI: 10.1016/J.Neuint.2020.104792  0.799
2019 Aggarwal S, Liu X, Rice C, Menell P, Clark P, Paparoidamis N, Xiao YC, Salvino JM, Fontana ACK, Espana RA, Kortagere S, Mortensen OV. IDENTIFICATION OF A NOVEL ALLOSTERIC MODULATOR OF THE HUMAN DOPAMINE TRANSPORTER. Acs Chemical Neuroscience. PMID 31184115 DOI: 10.1021/Acschemneuro.9B00262  0.668
2019 Marshall CA, Brodnik ZD, Mortensen OV, Reith MEA, Shumsky JS, Waterhouse BD, España RA, Kortagere S. Selective activation of Dopamine D3 receptors and norepinephrine transporter blockade enhances sustained attention. Neuropharmacology. 148: 178-188. PMID 30633928 DOI: 10.1016/J.Neuropharm.2019.01.003  0.519
2017 Aggarwal S, Mortensen OV. Overview of Monoamine Transporters. Current Protocols in Pharmacology. 79: 12.16.1-12.16.17. PMID 29261228 DOI: 10.1002/Cpph.32  0.617
2017 Aggarwal S, Mortensen OV. In Vitro Assays for the Functional Characterization of the Dopamine Transporter (DAT). Current Protocols in Pharmacology. 79: 12.17.1-12.17.21. PMID 29261226 DOI: 10.1002/Cpph.33  0.644
2017 Kortagere S, Mortensen OV, Xia J, Lester W, Fang Y, Srikanth YVV, Salvino JM, Fontana ACK. Identification of novel allosteric modulators of glutamate transporter EAAT2. Acs Chemical Neuroscience. PMID 29140675 DOI: 10.1021/Acschemneuro.7B00308  0.511
2017 Mortensen OV, Larsen MB, Amara SG. MAP Kinase Phosphatase 3 (MKP3) Preserves Norepinephrine Transporter Activity by Modulating ERK1/2 Kinase-Mediated Gene Expression. Frontiers in Cellular Neuroscience. 11: 253. PMID 28878626 DOI: 10.3389/Fncel.2017.00253  0.614
2015 Mortensen OV, Kortagere S. Designing modulators of monoamine transporters using virtual screening techniques. Frontiers in Pharmacology. 6: 223. PMID 26483692 DOI: 10.3389/Fphar.2015.00223  0.543
2015 Mortensen OV, Liberato JL, Coutinho-Netto J, Dos Santos WF, Fontana AC. Molecular determinants of transport stimulation of EAAT2 are located at interface between the trimerization and substrate transport domains. Journal of Neurochemistry. 133: 199-210. PMID 25626691 DOI: 10.1111/Jnc.13047  0.751
2013 Timple JM, Magalhães LG, Souza Rezende KC, Pereira AC, Cunha WR, Andrade e Silva ML, Mortensen OV, Fontana AC. The lignan (-)-hinokinin displays modulatory effects on human monoamine and GABA transporter activities. Journal of Natural Products. 76: 1889-95. PMID 24112084 DOI: 10.1021/Np400452N  0.764
2013 Kortagere S, Fontana ACK, Rose DR, Mortensen OV. Identification of an allosteric modulator of the serotonin transporter with novel mechanism of action Neuropharmacology. 72: 282-290. PMID 23632081 DOI: 10.1016/J.Neuropharm.2013.04.026  0.577
2013 Mortensen OV. MKP3 eliminates depolarization-dependent neurotransmitter release through downregulation of L-type calcium channel Cav1.2 expression. Cell Calcium. 53: 224-30. PMID 23337371 DOI: 10.1016/J.Ceca.2012.12.004  0.329
2011 Larsen MB, Sonders MS, Mortensen OV, Larson GA, Zahniser NR, Amara SG. Dopamine transport by the serotonin transporter: a mechanistically distinct mode of substrate translocation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6605-15. PMID 21525301 DOI: 10.1523/Jneurosci.0576-11.2011  0.736
2011 Larsen MB, Fontana AC, Magalhães LG, Rodrigues V, Mortensen OV. A catecholamine transporter from the human parasite Schistosoma mansoni with low affinity for psychostimulants. Molecular and Biochemical Parasitology. 177: 35-41. PMID 21251927 DOI: 10.1016/J.Molbiopara.2011.01.006  0.776
2009 Fontana AC, Sonders MS, Pereira-Junior OS, Knight M, Javitch JA, Rodrigues V, Amara SG, Mortensen OV. Two allelic isoforms of the serotonin transporter from Schistosoma mansoni display electrogenic transport and high selectivity for serotonin. European Journal of Pharmacology. 616: 48-57. PMID 19549517 DOI: 10.1016/J.Ejphar.2009.06.023  0.743
2008 Mortensen OV, Larsen MB, Prasad BM, Amara SG. Genetic complementation screen identifies a mitogen-activated protein kinase phosphatase, MKP3, as a regulator of dopamine transporter trafficking. Molecular Biology of the Cell. 19: 2818-29. PMID 18434601 DOI: 10.1091/Mbc.E07-09-0980  0.68
2006 Redman PT, Jefferson BS, Ziegler CB, Mortensen OV, Torres GE, Levitan ES, Aizenman E. A vital role for voltage-dependent potassium channels in dopamine transporter-mediated 6-hydroxydopamine neurotoxicity. Neuroscience. 143: 1-6. PMID 17027171 DOI: 10.1016/J.Neuroscience.2006.08.039  0.435
2006 Mortensen OV, Amara SG. Gain of function mutants reveal sites important for the interaction of the atypical inhibitors benztropine and bupropion with monoamine transporters. Journal of Neurochemistry. 98: 1531-40. PMID 16923164 DOI: 10.1111/J.1471-4159.2006.04060.X  0.727
2003 Mortensen OV, Amara SG. Dynamic regulation of the dopamine transporter. European Journal of Pharmacology. 479: 159-70. PMID 14612147 DOI: 10.1016/J.Ejphar.2003.08.066  0.738
2001 Mortensen OV, Kristensen AS, Wiborg O. Species-scanning mutagenesis of the serotonin transporter reveals residues essential in selective, high-affinity recognition of antidepressants. Journal of Neurochemistry. 79: 237-47. PMID 11677251 DOI: 10.1046/J.1471-4159.2001.00587.X  0.549
1999 Mortensen OV, Kristensen AS, Rudnick G, Wiborg O. Molecular cloning, expression and characterization of a bovine serotonin transporter. Brain Research. Molecular Brain Research. 71: 120-6. PMID 10407194 DOI: 10.1016/S0169-328X(99)00178-3  0.499
1999 Mortensen OV, Thomassen M, Larsen MB, Whittemore SR, Wiborg O. Functional analysis of a novel human serotonin transporter gene promoter in immortalized raphe cells. Brain Research. Molecular Brain Research. 68: 141-8. PMID 10320791 DOI: 10.1016/S0169-328X(99)00083-2  0.324
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