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Dianne Figlewicz - Publications

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
The modulation and regulation of CNS function by metabolic hormones (insulin, leptin) and metabolic status.

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Year Citation  Score
2015 Figlewicz DP. Modulation of Food Reward by Endocrine and Environmental Factors: Update and Perspective. Psychosomatic Medicine. 77: 664-70. PMID 25738439 DOI: 10.1097/PSY.0000000000000146  0.529
2013 Stice E, Figlewicz DP, Gosnell BA, Levine AS, Pratt WE. The contribution of brain reward circuits to the obesity epidemic. Neuroscience and Biobehavioral Reviews. 37: 2047-58. PMID 23237885 DOI: 10.1016/J.Neubiorev.2012.12.001  0.436
2013 Figlewicz DP, Jay JL, Acheson MA, Magrisso IJ, West CH, Zavosh A, Benoit SC, Davis JF. Moderate high fat diet increases sucrose self-administration in young rats. Appetite. 61: 19-29. PMID 23023044 DOI: 10.1016/J.Appet.2012.09.021  0.322
2012 Overduin J, Figlewicz DP, Bennett-Jay J, Kittleson S, Cummings DE. Ghrelin increases the motivation to eat, but does not alter food palatability. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 303: R259-69. PMID 22673784 DOI: 10.1152/ajpregu.00488.2011  0.643
2011 Figlewicz DP, Bennett-Jay JL, Kittleson S, Sipols AJ, Zavosh A. Sucrose self-administration and CNS activation in the rat. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 300: R876-84. PMID 21307361 DOI: 10.1152/ajpregu.00655.2010  0.324
2011 Davis JF, Choi DL, Schurdak JD, Fitzgerald MF, Clegg DJ, Lipton JW, Figlewicz DP, Benoit SC. Leptin regulates energy balance and motivation through action at distinct neural circuits. Biological Psychiatry. 69: 668-74. PMID 21035790 DOI: 10.1016/J.Biopsych.2010.08.028  0.579
2010 Figlewicz DP, Sipols AJ. Energy regulatory signals and food reward. Pharmacology, Biochemistry, and Behavior. 97: 15-24. PMID 20230849 DOI: 10.1016/j.pbb.2010.03.002  0.516
2009 Morton GJ, Blevins JE, Kim F, Matsen M, Figlewicz DP. The action of leptin in the ventral tegmental area to decrease food intake is dependent on Jak-2 signaling. American Journal of Physiology. Endocrinology and Metabolism. 297: E202-10. PMID 19435852 DOI: 10.1152/ajpendo.90865.2008  0.433
2009 Figlewicz DP, Benoit SC. Insulin, leptin, and food reward: update 2008. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 296: R9-R19. PMID 18945945 DOI: 10.1152/Ajpregu.90725.2008  0.475
2008 Figlewicz DP, Bennett JL, Aliakbari S, Zavosh A, Sipols AJ. Insulin acts at different CNS sites to decrease acute sucrose intake and sucrose self-administration in rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R388-94. PMID 18525010 DOI: 10.1152/ajpregu.90334.2008  0.382
2008 Naleid AM, Grimm JW, Kessler DA, Sipols AJ, Aliakbari S, Bennett JL, Wells J, Figlewicz DP. Deconstructing the vanilla milkshake: the dominant effect of sucrose on self-administration of nutrient-flavor mixtures. Appetite. 50: 128-38. PMID 17707949 DOI: 10.1016/J.Appet.2007.06.011  0.311
2007 Figlewicz DP, MacDonald Naleid A, Sipols AJ. Modulation of food reward by adiposity signals. Physiology & Behavior. 91: 473-8. PMID 17137609 DOI: 10.1016/J.Physbeh.2006.10.008  0.555
2006 Figlewicz DP, Bennett JL, Naleid AM, Davis C, Grimm JW. Intraventricular insulin and leptin decrease sucrose self-administration in rats. Physiology & Behavior. 89: 611-6. PMID 17045623 DOI: 10.1016/J.Physbeh.2006.07.023  0.414
2006 Sanders NM, Figlewicz DP, Taborsky GJ, Wilkinson CW, Daumen W, Levin BE. Feeding and neuroendocrine responses after recurrent insulin-induced hypoglycemia. Physiology & Behavior. 87: 700-6. PMID 16492385 DOI: 10.1016/J.Physbeh.2006.01.007  0.551
2004 Figlewicz DP, Bennett J, Evans SB, Kaiyala K, Sipols AJ, Benoit SC. Intraventricular insulin and leptin reverse place preference conditioned with high-fat diet in rats. Behavioral Neuroscience. 118: 479-87. PMID 15174925 DOI: 10.1037/0735-7044.118.3.479  0.459
2003 Figlewicz DP. Adiposity signals and food reward: expanding the CNS roles of insulin and leptin. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 284: R882-92. PMID 12626355 DOI: 10.1152/ajpregu.00602.2002  0.322
2002 Sipols AJ, Bayer J, Bennett R, Figlewicz DP. Intraventricular insulin decreases kappa opioid-mediated sucrose intake in rats. Peptides. 23: 2181-7. PMID 12535697 DOI: 10.1016/S0196-9781(02)00246-2  0.424
2002 Stuber GD, Evans SB, Higgins MS, Pu Y, Figlewicz DP. Food restriction modulates amphetamine-conditioned place preference and nucleus accumbens dopamine release in the rat. Synapse (New York, N.Y.). 46: 83-90. PMID 12211086 DOI: 10.1002/syn.10120  0.608
1998 Woods SC, Figlewicz DP, Madden L, Porte D, Sipols AJ, Seeley RJ. NPY and food intake: discrepancies in the model. Regulatory Peptides. 75: 403-8. PMID 9802436 DOI: 10.1016/S0167-0115(98)00095-0  0.515
1998 Bell SM, Reynolds JG, Thiele TE, Gan J, Figlewicz DP, Woods SC. Effects of third intracerebroventricular injections of corticotropin-releasing factor (CRF) on ethanol drinking and food intake. Psychopharmacology. 139: 128-35. PMID 9768550 DOI: 10.1007/s002130050697  0.306
1998 Patterson TA, Brot MD, Zavosh A, Schenk JO, Szot P, Figlewicz DP. Food deprivation decreases mRNA and activity of the rat dopamine transporter. Neuroendocrinology. 68: 11-20. PMID 9695934 DOI: 10.1159/000054345  0.431
1996 Sipols AJ, Figlewicz DP, Seeley RJ, Chavez M, Woods SC, Porte D. Intraventricular neuropeptide Y does not stimulate food intake in the baboon. Physiology & Behavior. 60: 717-9. PMID 8873242 DOI: 10.1016/0031-9384(96)00105-9  0.507
1996 Figlewicz DP, Schwartz MW, Seeley RJ, Chavez M, Baskin DG, Woods SC, Porte D. Endocrine regulation of food intake and body weight. The Journal of Laboratory and Clinical Medicine. 127: 328-32. PMID 8656034 DOI: 10.1016/S0022-2143(96)90179-1  0.485
1996 Woods SC, Chavez M, Park CR, Riedy C, Kaiyala K, Richardson RD, Figlewicz DP, Schwartz MW, Porte D, Seeley RJ. The evaluation of insulin as a metabolic signal influencing behavior via the brain. Neuroscience and Biobehavioral Reviews. 20: 139-44. PMID 8622820 DOI: 10.1016/0149-7634(95)00044-F  0.399
1995 Riedy CA, Chavez M, Figlewicz DP, Woods SC. Central insulin enhances sensitivity to cholecystokinin. Physiology & Behavior. 58: 755-60. PMID 8559787 DOI: 10.1016/0031-9384(95)00108-U  0.347
1995 Figlewicz DP, Sipols AJ, Seeley RJ, Chavez M, Woods SC, Porte D. Intraventricular insulin enhances the meal-suppressive efficacy of intraventricular cholecystokinin octapeptide in the baboon. Behavioral Neuroscience. 109: 567-9. PMID 7662167 DOI: 10.1037//0735-7044.109.3.567  0.337
1993 Weatherford SC, Figlewicz DP, Park CR, Woods SC. Chronic alcohol consumption increases sensitivity to the anorexic effect of cholecystokinin. The American Journal of Physiology. 265: R211-5. PMID 8342689 DOI: 10.1152/Ajpregu.1993.265.1.R211  0.301
1993 Schwartz MW, Figlewicz DP, Woods SC, Porte D, Baskin DG. Insulin, neuropeptide Y, and food intake. Annals of the New York Academy of Sciences. 692: 60-71. PMID 8215045 DOI: 10.1111/J.1749-6632.1993.Tb26206.X  0.508
1990 Figlewicz D, Szot P, Greenwood MR. Insulin stimulates inositol incorporation in hippocampus of lean but not obese Zucker rats. Physiology & Behavior. 47: 325-30. PMID 2159162 DOI: 10.1016/0031-9384(90)90150-3  0.334
1988 Bohannon NJ, Corp ES, Wilcox BJ, Figlewicz DP, Dorsa DM, Baskin DG. Characterization of insulin-like growth factor I receptors in the median eminence of the brain and their modulation by food restriction. Endocrinology. 122: 1940-7. PMID 2966061 DOI: 10.1210/endo-122-5-1940  0.382
1987 Stein LJ, Dorsa DM, Baskin DG, Figlewicz DP, Porte D, Woods SC. Reduced effect of experimental peripheral hyperinsulinemia to elevate cerebrospinal fluid insulin concentrations of obese Zucker rats. Endocrinology. 121: 1611-5. PMID 3311715 DOI: 10.1210/endo-121-5-1611  0.309
1986 Ikeda H, West DB, Pustek JJ, Figlewicz DP, Greenwood MR, Porte D, Woods SC. Intraventricular insulin reduces food intake and body weight of lean but not obese Zucker rats. Appetite. 7: 381-6. PMID 3539015 DOI: 10.1016/S0195-6663(86)80006-X  0.4
1986 Figlewicz DP, Stein LJ, West D, Porte D, Woods SC. Intracisternal insulin alters sensitivity to CCK-induced meal suppression in baboons. The American Journal of Physiology. 250: R856-60. PMID 3518496 DOI: 10.1152/Ajpregu.1986.250.5.R856  0.311
1986 Stein LJ, Porte D, Figlewicz DP, Woods SC. Effect of fasting interval on CCK-8 suppression of food intake in the baboon. The American Journal of Physiology. 250: R851-5. PMID 3518495  0.492
1985 Figlewicz DP, Stein LJ, Woods SC, Porte D. Acute and chronic gastrin-releasing peptide decreases food intake in baboons. The American Journal of Physiology. 248: R578-83. PMID 3887950 DOI: 10.1152/Ajpregu.1985.248.5.R578  0.503
1983 Woods SC, Stein LJ, Figlewicz DP, Porte D. Bombesin stimulates insulin secretion and reduces food intake in the baboon. Peptides. 4: 687-91. PMID 6361710 DOI: 10.1016/0196-9781(83)90019-0  0.492
1983 Stein LJ, Dorsa DM, Baskin DG, Figlewicz DP, Ikeda H, Frankmann SP, Greenwood MR, Porte D, Woods SC. Immunoreactive insulin levels are elevated in the cerebrospinal fluid of genetically obese Zucker rats. Endocrinology. 113: 2299-301. PMID 6357768 DOI: 10.1210/endo-113-6-2299  0.308
Low-probability matches (unlikely to be authored by this person)
1992 Schwartz MW, Sipols AJ, Marks JL, Sanacora G, White JD, Scheurink A, Kahn SE, Baskin DG, Woods SC, Figlewicz DP. Inhibition of hypothalamic neuropeptide Y gene expression by insulin. Endocrinology. 130: 3608-16. PMID 1597158 DOI: 10.1210/Endo.130.6.1597158  0.299
2017 Figlewicz DP, Jay J, West CH, Zavosh A, Hampe CS, Radtke JR, Raskind MA, Peskind ER. Effect of dietary palmitic and stearic acids on sucrose motivation and hypothalamic and striatal cell signals in the rat. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00340.2017. PMID 29092861 DOI: 10.1152/ajpregu.00340.2017  0.288
1989 Figlewicz DP, Sipols AJ, Porte D, Woods SC, Liddle RA. Intraventricular CCK inhibits food intake and gastric emptying in baboons. The American Journal of Physiology. 256: R1313-7. PMID 2735457 DOI: 10.1152/Ajpregu.1989.256.6.R1313  0.287
2003 Figlewicz DP. Insulin, food intake, and reward. Seminars in Clinical Neuropsychiatry. 8: 82-93. PMID 12728408 DOI: 10.1053/scnp.2003.50012  0.277
1993 Israel PA, Park CR, Schwartz MW, Green PK, Sipols AJ, Woods SC, Porte D, Figlewicz DP. Effect of diet-induced obesity and experimental hyperinsulinemia on insulin uptake into CSF of the rat. Brain Research Bulletin. 30: 571-5. PMID 8457906 DOI: 10.1016/0361-9230(93)90084-O  0.273
2009 Figlewicz DP, Ioannou G, Bennett Jay J, Kittleson S, Savard C, Roth CL. Effect of moderate intake of sweeteners on metabolic health in the rat. Physiology & Behavior. 98: 618-24. PMID 19815021 DOI: 10.1016/j.physbeh.2009.09.016  0.273
1986 Figlewicz DP, Woods SC, Porte D, Taborsky GJ. Effect of CCK-8 on basal and meal-stimulated somatostatin in the baboon. Peptides. 7: 771-4. PMID 2879277 DOI: 10.1016/0196-9781(86)90094-X  0.27
1985 Figlewicz DP, Dorsa DM, Stein LJ, Baskin DG, Paquette T, Greenwood MR, Woods SC, Porte D. Brain and liver insulin binding is decreased in Zucker rats carrying the 'fa' gene. Endocrinology. 117: 1537-43. PMID 3896761 DOI: 10.1210/endo-117-4-1537  0.269
1986 Figlewicz DP, Ikeda H, Hunt TR, Stein LJ, Dorsa DM, Woods SC, Porte D. Brain insulin binding is decreased in Wistar Kyoto rats carrying the 'fa' gene. Peptides. 7: 61-5. PMID 3714533 DOI: 10.1016/0196-9781(86)90062-8  0.264
1994 Figlewicz DP, Szot P, Chavez M, Woods SC, Veith RC. Intraventricular insulin increases dopamine transporter mRNA in rat VTA/substantia nigra. Brain Research. 644: 331-4. PMID 8050044 DOI: 10.1016/0006-8993(94)91698-5  0.263
2004 Figlewicz DP, Zavosh A, Sexton T, Neumaier JF. Catabolic action of insulin in rat arcuate nucleus is not enhanced by exogenous "tub" expression. American Journal of Physiology. Endocrinology and Metabolism. 286: E1004-10. PMID 14749205 DOI: 10.1152/Ajpendo.00427.2003  0.259
1985 Baskin DG, Stein LJ, Ikeda H, Woods SC, Figlewicz DP, Porte D, Greenwood MR, Dorsa DM. Genetically obese Zucker rats have abnormally low brain insulin content. Life Sciences. 36: 627-33. PMID 3881641 DOI: 10.1016/0024-3205(85)90166-3  0.259
2015 Figlewicz DP. EXPRESSION OF RECEPTORS FOR INSULIN AND LEPTIN IN THE VENTRAL TEGMENTAL AREA/SUBSTANTIA NIGRA (VTA/SN) OF THE RAT:HISTORICAL PERSPECTIVE. Brain Research. PMID 26731335 DOI: 10.1016/j.brainres.2015.12.041  0.257
2000 Sipols AJ, Stuber GD, Klein SN, Higgins MS, Figlewicz DP. Insulin and raclopride combine to decrease short-term intake of sucrose solutions. Peptides. 21: 1361-7. PMID 11072123 DOI: 10.1016/S0196-9781(00)00279-5  0.253
2008 Sanders NM, Wilkinson CW, Taborsky GJ, Al-Noori S, Daumen W, Zavosh A, Figlewicz DP. The selective serotonin reuptake inhibitor sertraline enhances counterregulatory responses to hypoglycemia. American Journal of Physiology. Endocrinology and Metabolism. 294: E853-60. PMID 18334609 DOI: 10.1152/ajpendo.00772.2007  0.252
2014 Figlewicz DP, Hill SR, Jay JL, West CH, Zavosh AS, Sipols AJ. Effect of recurrent yohimbine on immediate and post-hoc behaviors, stress hormones, and energy homeostatic parameters. Physiology & Behavior. 129: 186-93. PMID 24565792 DOI: 10.1016/j.physbeh.2014.02.019  0.248
2006 Pardini AW, Nguyen HT, Figlewicz DP, Baskin DG, Williams DL, Kim F, Schwartz MW. Distribution of insulin receptor substrate-2 in brain areas involved in energy homeostasis. Brain Research. 1112: 169-78. PMID 16925984 DOI: 10.1016/J.Brainres.2006.06.109  0.247
1993 Figlewicz DP, Szot P, Israel PA, Payne C, Dorsa DM. Insulin reduces norepinephrine transporter mRNA in vivo in rat locus coeruleus. Brain Research. 602: 161-4. PMID 8448653 DOI: 10.1016/0006-8993(93)90258-O  0.242
2003 Figlewicz DP, Evans SB, Murphy J, Hoen M, Baskin DG. Expression of receptors for insulin and leptin in the ventral tegmental area/substantia nigra (VTA/SN) of the rat. Brain Research. 964: 107-15. PMID 12573518 DOI: 10.1016/S0006-8993(02)04087-8  0.235
1996 Figlewicz DP, Brot MD, McCall AL, Szot P. Diabetes causes differential changes in CNS noradrenergic and dopaminergic neurons in the rat: a molecular study. Brain Research. 736: 54-60. PMID 8930308 DOI: 10.1016/0006-8993(96)00727-5  0.234
1989 Wilcox BJ, Corp ES, Dorsa DM, Figlewicz DP, Greenwood MR, Woods SC, Baskin DG. Insulin binding in the hypothalamus of lean and genetically obese Zucker rats. Peptides. 10: 1159-64. PMID 2622801 DOI: 10.1016/0196-9781(89)90008-9  0.23
1998 Figlewicz DP, Patterson TA, Johnson LB, Zavosh A, Israel PA, Szot P. Dopamine transporter mRNA is increased in the CNS of Zucker fatty (fa/fa) rats. Brain Research Bulletin. 46: 199-202. PMID 9667812  0.229
1992 Figlewicz DP, Nadzan AM, Sipols AJ, Green PK, Liddle RA, Porte D, Woods SC. Intraventricular CCK-8 reduces single meal size in the baboon by interaction with type-A CCK receptors. The American Journal of Physiology. 263: R863-7. PMID 1415799 DOI: 10.1152/Ajpregu.1992.263.4.R863  0.223
2001 Figlewicz DP, Higgins MS, Ng-Evans SB, Havel PJ. Leptin reverses sucrose-conditioned place preference in food-restricted rats. Physiology & Behavior. 73: 229-34. PMID 11399316 DOI: 10.1016/S0031-9384(01)00486-3  0.22
2000 Thompson SC, Woods SC, Hendricks S, Bell SM, Figlewicz DP. Intraventricular insulin suppresses the acoustic startle response in rats. Physiology & Behavior. 69: 433-7. PMID 10913781 DOI: 10.1016/S0031-9384(99)00260-7  0.219
1986 Corp ES, Woods SC, Porte D, Dorsa DM, Figlewicz DP, Baskin DG. Localization of 125I-insulin binding sites in the rat hypothalamus by quantitative autoradiography. Neuroscience Letters. 70: 17-22. PMID 3534636 DOI: 10.1016/0304-3940(86)90430-1  0.208
1987 Wallum BJ, Taborsky GJ, Porte D, Figlewicz DP, Jacobson L, Beard JC, Ward WK, Dorsa D. Cerebrospinal fluid insulin levels increase during intravenous insulin infusions in man. The Journal of Clinical Endocrinology and Metabolism. 64: 190-4. PMID 3536982 DOI: 10.1210/jcem-64-1-190  0.203
1980 Figlewicz DP, Formby B, Hodgson AT, Schmid FG, Grodsky GM. Kinetics of 65zinc uptake and distribution in fractions from cultured rat islets of langerhans. Diabetes. 29: 767-73. PMID 7002658  0.201
2002 Figlewicz DP, Van Dijk G, Wilkinson CW, Gronbeck P, Higgins M, Zavosh A. Effects of repetitive hypoglycemia on neuroendocrine response and brain tyrosine hydroxylase activity in the rat. Stress (Amsterdam, Netherlands). 5: 217-26. PMID 12186684 DOI: 10.1080/1025389021000010558  0.2
1989 Figlewicz DP, Sipols AJ, Green P, Porte D, Woods SC. IVT CCK-8 is more effective than IV CCK-8 at decreasing meal size in the baboon. Brain Research Bulletin. 22: 849-52. PMID 2765945 DOI: 10.1016/0361-9230(89)90029-4  0.199
1990 Schwartz MW, Figlewicz DF, Kahn SE, Baskin DG, Greenwood MR, Porte D. Insulin binding to brain capillaries is reduced in genetically obese, hyperinsulinemic Zucker rats. Peptides. 11: 467-72. PMID 2199946 DOI: 10.1016/0196-9781(90)90044-6  0.197
2010 Figlewicz D, Ioannou G, Bennett Jay J, Kittleson S, Savard C, Roth C. Corrigendum to “Effect of moderate intake of sweeteners on metabolic health in the rat” [Physiology & Behavior. 98/5 (2009) 618–624] Physiology & Behavior. 99: 691. DOI: 10.1016/j.physbeh.2009.11.011  0.193
1999 Roitman MF, Patterson TA, Sakai RR, Bernstein IL, Figlewicz DP. Sodium depletion and aldosterone decrease dopamine transporter activity in nucleus accumbens but not striatum. The American Journal of Physiology. 276: R1339-45. PMID 10233025 DOI: 10.1152/Ajpregu.1999.276.5.R1339  0.193
2001 Evans SB, Wilkinson CW, Bentson K, Gronbeck P, Zavosh A, Figlewicz DP. PVN activation is suppressed by repeated hypoglycemia but not antecedent corticosterone in the rat. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 281: R1426-36. PMID 11641112  0.19
1999 Roitman MF, Patterson TA, Sakai RR, Bernstein IL, Figlewicz DP. Sodium depletion and aldosterone decrease dopamine transporter activity in nucleus accumbens but not striatum. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 276: R1339-R1345. PMID 29592661 DOI: 10.1152/ajpregu.1999.276.5.R1339  0.176
2017 Hlavica M, Delparente A, Good A, Good N, Plattner PS, Seyedsadr MS, Schwab ME, Figlewicz DP, Ineichen BV. Intrathecal insulin-like growth factor 1 but not insulin enhances myelin repair in young and aged rats. Neuroscience Letters. PMID 28363754 DOI: 10.1016/j.neulet.2017.03.047  0.174
1993 Figlewicz DP, Bentson K, Ocrant I. The effect of insulin on norepinephrine uptake by PC12 cells. Brain Research Bulletin. 32: 425-31. PMID 8221132 DOI: 10.1016/0361-9230(93)90210-3  0.173
1991 Figlewicz DP, Szot P. Insulin stimulates membrane phospholipid metabolism by enhancing endogenous alpha 1-adrenergic activity in the rat hippocampus. Brain Research. 550: 101-7. PMID 1653632 DOI: 10.1016/0006-8993(91)90410-W  0.17
1986 Baskin DG, Brewitt B, Davidson DA, Corp E, Paquette T, Figlewicz DP, Lewellen TK, Graham MK, Woods SG, Dorsa DM. Quantitative autoradiographic evidence for insulin receptors in the choroid plexus of the rat brain. Diabetes. 35: 246-9. PMID 3510931 DOI: 10.2337/Diab.35.2.246  0.166
1978 Figlewicz DA, Hofteig JH, Druse MJ. Maternal deficiency of protein or protein and calories during lactation: effect upon CNS myelin subfraction formation in rat offspring. Life Sciences. 23: 2163-72. PMID 102890 DOI: 10.1016/0024-3205(78)90190-X  0.166
1984 Figlewicz DP, Forhan SE, Hodgson AT, Grodsky GM. 65Zinc and endogenous zinc content and distribution in islets in relationship to insulin content. Endocrinology. 115: 877-81. PMID 6378606 DOI: 10.1210/endo-115-3-877  0.165
2004 Evans SB, Wilkinson CW, Gronbeck P, Bennett JL, Zavosh A, Taborsky GJ, Figlewicz DP. Inactivation of the DMH selectively inhibits the ACTH and corticosterone responses to hypoglycemia. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 286: R123-8. PMID 14660476 DOI: 10.1152/ajpregu.00328.2003  0.157
2012 Roth CL, Elfers CT, Figlewicz DP, Melhorn SJ, Morton GJ, Hoofnagle A, Yeh MM, Nelson JE, Kowdley KV. Vitamin D deficiency in obese rats exacerbates nonalcoholic fatty liver disease and increases hepatic resistin and Toll-like receptor activation. Hepatology (Baltimore, Md.). 55: 1103-11. PMID 21994008 DOI: 10.1002/hep.24737  0.156
2003 Mundinger TO, Mei Q, Figlewicz DP, Lernmark A, Taborsky GJ. Impaired glucagon response to sympathetic nerve stimulation in the BB diabetic rat: effect of early sympathetic islet neuropathy. American Journal of Physiology. Endocrinology and Metabolism. 285: E1047-54. PMID 12876072 DOI: 10.1152/Ajpendo.00136.2003  0.156
2003 Evans SB, Wilkinson CW, Gronbeck P, Bennett JL, Taborsky GJ, Figlewicz DP. Inactivation of the PVN during hypoglycemia partially simulates hypoglycemia-associated autonomic failure. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 284: R57-65. PMID 12388440 DOI: 10.1152/ajpregu.00439.2002  0.154
1987 Baskin DG, Figlewicz DP, Woods SC, Porte D, Dorsa DM. Insulin in the brain. Annual Review of Physiology. 49: 335-47. PMID 3551804 DOI: 10.1146/annurev.ph.49.030187.002003  0.154
2008 Al-Noori S, Sanders NM, Taborsky GJ, Wilkinson CW, Zavosh A, West C, Sanders CM, Figlewicz DP. Recurrent hypoglycemia alters hypothalamic expression of the regulatory proteins FosB and synaptophysin. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R1446-54. PMID 18753263 DOI: 10.1152/ajpregu.90511.2008  0.154
1981 Figlewicz DP, Heldt A, Forhan SE, Grodsky GM. Effect of exogenous zinc on insulin secretion in vitro. Endocrinology. 108: 730-2. PMID 7004863 DOI: 10.1210/endo-108-2-730  0.147
1986 Bohannon NJ, Figlewicz DP, Corp ES, Wilcox BJ, Porte D, Baskin DG. Identification of binding sites for an insulin-like growth factor (IGF-I) in the median eminence of the rat brain by quantitative autoradiography. Endocrinology. 119: 943-5. PMID 3015561 DOI: 10.1210/endo-119-2-943  0.144
1999 Figlewicz DP. Endocrine regulation of neurotransmitter transporters. Epilepsy Research. 37: 203-10. PMID 10584970 DOI: 10.1016/S0920-1211(99)00072-8  0.14
1988 Bohannon NJ, Corp ES, Wilcox BJ, Figlewicz DP, Dorsa DM, Baskin DG. Localization of binding sites for insulin-like growth factor-I (IGF-I) in the rat brain by quantitative autoradiography. Brain Research. 444: 205-13. PMID 3359292 DOI: 10.1016/0006-8993(88)90931-6  0.14
2007 Sanders NM, Taborsky GJ, Wilkinson CW, Daumen W, Figlewicz DP. Antecedent hindbrain glucoprivation does not impair the counterregulatory response to hypoglycemia. Diabetes. 56: 217-23. PMID 17192485 DOI: 10.2337/db06-1025  0.137
1983 Figlewicz DP, Best JD, Tager HS, Taborsky GJ. [LeuB24]insulin is an insulin agonist at the liver in vivo. The American Journal of Physiology. 245: E483-8. PMID 6356934  0.137
1986 Figlewicz DP, Sipols A, Porte D, Woods SC. Intraventricular bombesin can decrease single meal size in the baboon. Brain Research Bulletin. 17: 535-7. PMID 3779453 DOI: 10.1016/0361-9230(86)90222-4  0.135
1992 Schwartz MW, Figlewicz DP, Baskin DG, Woods SC, Porte D. Insulin in the brain: a hormonal regulator of energy balance. Endocrine Reviews. 13: 387-414. PMID 1425482 DOI: 10.1210/Edrv-13-3-387  0.135
1983 Quarles RH, Barbarash GR, Figlewicz DA, McIntyre LJ. Purification and partial characterization of the myelin-associated glycoprotein from adult rat brain. Biochimica Et Biophysica Acta. 757: 140-3. PMID 6188493 DOI: 10.1016/0304-4165(83)90162-9  0.129
2000 Figlewicz DP, Woods SC. Adiposity signals and brain reward mechanisms. Trends in Pharmacological Sciences. 21: 235-6. PMID 10871887 DOI: 10.1016/S0165-6147(00)01488-7  0.125
1988 Baskin DG, Wilcox BJ, Figlewicz DP, Dorsa DM. Insulin and insulin-like growth factors in the CNS. Trends in Neurosciences. 11: 107-11. PMID 2465607 DOI: 10.1016/0166-2236(88)90155-5  0.116
1981 Figlewicz DA, Quarles RH, Johnson D, Barbarash GR, Sternberger NH. Biochemical demonstration of the myelin-associated glycoprotein in the peripheral nervous system. Journal of Neurochemistry. 37: 749-58. PMID 6168745 DOI: 10.1111/j.1471-4159.1982.tb12551.x  0.115
2008 Al-Noori S, Sanders NM, Taborsky GJ, Wilkinson CW, Figlewicz DP. Acute THPVP inactivation decreases the glucagon and sympathoadrenal responses to recurrent hypoglycemia. Brain Research. 1194: 65-72. PMID 18191818 DOI: 10.1016/j.brainres.2007.11.040  0.112
1986 Heidenreich KA, Freidenberg GR, Figlewicz DP, Gilmore PR. Evidence for a subtype of insulin-like growth factor I receptor in brain. Regulatory Peptides. 15: 301-10. PMID 2948220 DOI: 10.1016/0167-0115(86)90160-6  0.104
1983 Figlewicz DP, Best JD, Tager HS, Taborsky GJ. [Leu(B24)]insulin is an insulin agonist at the liver in vivo American Journal of Physiology - Endocrinology and Metabolism. 8: E483-E488.  0.099
1999 Figlewicz DP, Patterson TA, Zavosh A, Brot MD, Roitman M, Szot P. Neurotransmitter transporters: target for endocrine regulation. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Mã©Tabolisme. 31: 335-9. PMID 10422731 DOI: 10.1055/s-2007-978749  0.099
2001 Manning P, Cookson MR, McNeil CJ, Figlewicz D, Shaw PJ. Superoxide-induced nitric oxide release from cultured glial cells. Brain Research. 911: 203-10. PMID 11511391 DOI: 10.1016/S0006-8993(01)02688-9  0.099
1993 Garofalo O, Figlewicz DA, Leigh PN, Powell JF, Meininger V, Dib M, Rouleau GA. Androgen receptor gene polymorphisms in amyotrophic lateral sclerosis. Neuromuscular Disorders : Nmd. 3: 195-9. PMID 8400860 DOI: 10.1016/0960-8966(93)90059-S  0.099
1999 Zavosh A, Schaefer J, Ferrel A, Figlewicz DP. Desipramine treatment decreases 3H-nisoxetine binding and norepinephrine transporter mRNA in SK-N-SHSY5Y cells. Brain Research Bulletin. 49: 291-5. PMID 10424850 DOI: 10.1016/S0361-9230(99)00063-5  0.095
1979 Filkins JP, Figlewicz DP. Increased insulin responsiveness in endotoxicosis. Circulatory Shock. 6: 1-6. PMID 378453  0.094
1993 Figlewicz DA, Delattre O, Guellaen G, Krizus A, Thomas G, Zucman J, Rouleau GA. Mapping of human gamma-glutamyl transpeptidase genes on chromosome 22 and other human autosomes. Genomics. 17: 299-305. PMID 8104871 DOI: 10.1006/Geno.1993.1325  0.092
1999 Mohajeri MH, Figlewicz DA, Bohn MC. Intramuscular grafts of myoblasts genetically modified to secrete glial cell line-derived neurotrophic factor prevent motoneuron loss and disease progression in a mouse model of familial amyotrophic lateral sclerosis. Human Gene Therapy. 10: 1853-66. PMID 10446925 DOI: 10.1089/10430349950017536  0.091
1982 Figlewicz DP, Tager H, Taborsky GJ. Leu-B24-insulin does not antagonize insulin action at the liver in vivo Diabetes. 31: No. 57.  0.089
1993 Mhatre AN, Trifiro MA, Kaufman M, Kazemi-Esfarjani P, Figlewicz D, Rouleau G, Pinsky L. Reduced transcriptional regulatory competence of the androgen receptor in X-linked spinal and bulbar muscular atrophy. Nature Genetics. 5: 184-8. PMID 8252045 DOI: 10.1038/Ng1093-184  0.087
2005 Slowik A, Borratynska A, Turaj W, Pera J, Dziedzic T, Figlewicz DA, Betlej M, Krzyszkowski T, Czepko R, Szczudlik A. Alpha1-antichymotrypsin gene (SERPINA3) A/T polymorphism as a risk factor for aneurysmal subarachnoid hemorrhage. Stroke; a Journal of Cerebral Circulation. 36: 737-40. PMID 15718509 DOI: 10.1161/01.STR.0000157598.02014.37  0.085
2014 Lunt PW, Figlewicz DA. Epigenetic hypomethylation in FSHD: it's not what you inherit, it's whether it shows. Neurology. 83: 674-5. PMID 25031285 DOI: 10.1212/Wnl.0000000000000726  0.082
1998 Mohajeri MH, Figlewicz DA, Bohn MC. Selective loss of alpha motoneurons innervating the medial gastrocnemius muscle in a mouse model of amyotrophic lateral sclerosis. Experimental Neurology. 150: 329-36. PMID 9527903 DOI: 10.1006/Exnr.1998.6758  0.082
2001 Orrell RW, Figlewicz DA. Clinical implications of the genetics of ALS and other motor neuron diseases. Neurology. 57: 9-17. PMID 11460829 DOI: 10.1212/Wnl.57.1.9  0.079
2020 Figlewicz DP, Witkamp RF. FATTY ACIDS AS CELL SIGNALS IN INGESTIVE BEHAVIORS. Physiology & Behavior. 112985. PMID 32473927 DOI: 10.1016/j.physbeh.2020.112985  0.074
1978 Figlewicz DP, Filkins JP. Dexamethasone antagonism of glucose dyshomeostasis in endotoxin shock. Circulatory Shock. 5: 317-23. PMID 280423  0.073
2002 Menzies FM, Cookson MR, Taylor RW, Turnbull DM, Chrzanowska-Lightowlers ZM, Dong L, Figlewicz DA, Shaw PJ. Mitochondrial dysfunction in a cell culture model of familial amyotrophic lateral sclerosis. Brain : a Journal of Neurology. 125: 1522-33. PMID 12077002 DOI: 10.1093/Brain/Awf167  0.072
1994 Figlewicz DA, McInnis MG, Goto J, Haines JL, Warren AC, Krizus A, Khodr N, Brown RH, McKenna-Yasek D, Antonarakis SE. Identification of flanking markers for the familial amyotrophic lateral sclerosis gene ALS1 on chromosome 21. Journal of the Neurological Sciences. 124: 90-5. PMID 7807155 DOI: 10.1016/0022-510X(94)90190-2  0.072
2000 Derby ML, Giuliano R, Figlewicz DA, Bohn MC. GDNF is trophic for mouse motoneurons that express a mutant superoxide dismutase (SOD-1) gene. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 1: 113-22. PMID 11467048 DOI: 10.1080/14660820050515412  0.072
1998 Porte D, Seeley RJ, Woods SC, Baskin DG, Figlewicz DP, Schwartz MW. Obesity, diabetes and the central nervous system. Diabetologia. 41: 863-81. PMID 9726588 DOI: 10.1007/S001250051002  0.07
1996 Tawil R, Forrester J, Griggs RC, Mendell J, Kissel J, McDermott M, King W, Weiffenbach B, Figlewicz D. Evidence for anticipation and association of deletion size with severity in facioscapulohumeral muscular dystrophy. The FSH-DY Group. Annals of Neurology. 39: 744-8. PMID 8651646 DOI: 10.1002/Ana.410390610  0.068
2008 Kabashi E, Agar JN, Hong Y, Taylor DM, Minotti S, Figlewicz DA, Durham HD. Proteasomes remain intact, but show early focal alteration in their composition in a mouse model of amyotrophic lateral sclerosis. Journal of Neurochemistry. 105: 2353-66. PMID 18315558 DOI: 10.1111/J.1471-4159.2008.05317.X  0.068
1995 Durham HD, O'Brien C, Nalbantoglu J, Figlewicz DA. Use of tissue culture models to study environmental-genetic interactions relevant to neurodegenerative diseases. Clinical and Experimental Pharmacology & Physiology. 22: 366-7. PMID 7554432 DOI: 10.1111/J.1440-1681.1995.Tb02019.X  0.068
1998 Tawil R, Figlewicz DA, Griggs RC, Weiffenbach B. Facioscapulohumeral dystrophy: a distinct regional myopathy with a novel molecular pathogenesis. FSH Consortium. Annals of Neurology. 43: 279-82. PMID 9506542 DOI: 10.1002/Ana.410430303  0.066
1998 Roy J, Minotti S, Dong L, Figlewicz DA, Durham HD. Glutamate potentiates the toxicity of mutant Cu/Zn-superoxide dismutase in motor neurons by postsynaptic calcium-dependent mechanisms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 9673-84. PMID 9822728 DOI: 10.1523/Jneurosci.18-23-09673.1998  0.065
1996 Rubio A, Steinberg K, Figlewicz DA, MacDonald ME, Greenamyre T, Hamill R, Shoulson I, Powers JM. Coexistence of Huntington's disease and familial amyotrophic lateral sclerosis: case presentation. Acta Neuropathologica. 92: 421-7. PMID 8891076 DOI: 10.1007/S004010050539  0.065
2008 Al-Noori S, Sanders NM, Taborsky GJ, Wilkinson CW, Figlewicz DP. Corrigendum to "Acute THPVP inactivation decreases the glucagon and sympathoadrenal responses to recurrent hypoglycemia" [Brain Res. 1194 (2008) 65-72] (DOI:10.1016/j.brainres.2007.11.040) Brain Research. 1243: 175. DOI: 10.1016/j.brainres.2008.08.035  0.064
2006 Slowik A, Tomik B, Wolkow PP, Partyka D, Turaj W, Malecki MT, Pera J, Dziedzic T, Szczudlik A, Figlewicz DA. Paraoxonase gene polymorphisms and sporadic ALS. Neurology. 67: 766-70. PMID 16822965 DOI: 10.1212/01.wnl.0000219565.32247.11  0.064
2001 Tsien F, Sun B, Hopkins NE, Vedanarayanan V, Figlewicz D, Winokur S, Ehrlich M. Methylation of the FSHD syndrome-linked subtelomeric repeat in normal and FSHD cell cultures and tissues. Molecular Genetics and Metabolism. 74: 322-31. PMID 11708861 DOI: 10.1006/Mgme.2001.3219  0.063
1980 Figlewicz DA, Druse MJ. Experimental hyperphenylalaninemia: effect on central nervous system myelin subfractions. Experimental Neurology. 67: 315-29. PMID 7349991 DOI: 10.1016/0014-4886(80)90232-0  0.062
2004 Devlin B, Bennett P, Dawson G, Figlewicz DA, Grigorenko EL, McMahon W, Minshew N, Pauls D, Smith M, Spence MA, Rodier PM, Stodgell C, Schellenberg GD. Alleles of a reelin CGG repeat do not convey liability to autism in a sample from the CPEA network. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 126: 46-50. PMID 15048647 DOI: 10.1002/Ajmg.B.20125  0.061
2003 Winokur ST, Barrett K, Martin JH, Forrester JR, Simon M, Tawil R, Chung SA, Masny PS, Figlewicz DA. Facioscapulohumeral muscular dystrophy (FSHD) myoblasts demonstrate increased susceptibility to oxidative stress. Neuromuscular Disorders : Nmd. 13: 322-33. PMID 12868502 DOI: 10.1016/S0960-8966(02)00284-5  0.06
2002 Cookson MR, Menzies FM, Manning P, Eggett CJ, Figlewicz DA, McNeil CJ, Shaw PJ. Cu/Zn superoxide dismutase (SOD1) mutations associated with familial amyotrophic lateral sclerosis (ALS) affect cellular free radical release in the presence of oxidative stress. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 3: 75-85. PMID 12215229 DOI: 10.1080/146608202760196048  0.06
2000 Ingram JL, Stodgell CJ, Hyman SL, Figlewicz DA, Weitkamp LR, Rodier PM. Discovery of allelic variants of HOXA1 and HOXB1: genetic susceptibility to autism spectrum disorders. Teratology. 62: 393-405. PMID 11091361 DOI: 10.1002/1096-9926(200012)62:6<393::Aid-Tera6>3.0.Co;2-V  0.059
2009 Strong MJ, Grace GM, Freedman M, Lomen-Hoerth C, Woolley S, Goldstein LH, Murphy J, Shoesmith C, Rosenfeld J, Leigh PN, Bruijn L, Ince P, Figlewicz D. Consensus criteria for the diagnosis of frontotemporal cognitive and behavioural syndromes in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 10: 131-46. PMID 19462523 DOI: 10.1080/17482960802654364  0.059
2009 Wills AM, Cronin S, Slowik A, Kasperaviciute D, Van Es MA, Morahan JM, Valdmanis PN, Meininger V, Melki J, Shaw CE, Rouleau GA, Fisher EM, Shaw PJ, Morrison KE, Pamphlett R, ... ... Figlewicz DA, et al. A large-scale international meta-analysis of paraoxonase gene polymorphisms in sporadic ALS. Neurology. 73: 16-24. PMID 19321847 DOI: 10.1212/Wnl.0B013E3181A18674  0.059
2002 Menzies FM, Grierson AJ, Cookson MR, Heath PR, Tomkins J, Figlewicz DA, Ince PG, Shaw PJ. Selective loss of neurofilament expression in Cu/Zn superoxide dismutase (SOD1) linked amyotrophic lateral sclerosis. Journal of Neurochemistry. 82: 1118-28. PMID 12358759 DOI: 10.1046/J.1471-4159.2002.01045.X  0.058
1996 Rouleau GA, Clark AW, Rooke K, Pramatarova A, Krizus A, Suchowersky O, Julien JP, Figlewicz D. SOD1 mutation is associated with accumulation of neurofilaments in amyotrophic lateral sclerosis. Annals of Neurology. 39: 128-31. PMID 8572658 DOI: 10.1002/Ana.410390119  0.058
1999 Bruening W, Roy J, Giasson B, Figlewicz DA, Mushynski WE, Durham HD. Up-regulation of protein chaperones preserves viability of cells expressing toxic Cu/Zn-superoxide dismutase mutants associated with amyotrophic lateral sclerosis. Journal of Neurochemistry. 72: 693-9. PMID 9930742 DOI: 10.1046/J.1471-4159.1999.0720693.X  0.057
2001 Doroudchi MM, Minotti S, Figlewicz DA, Durham HD. Nitrotyrosination contributes minimally to toxicity of mutant SOD1 associated with ALS. Neuroreport. 12: 1239-43. PMID 11338199  0.057
2003 Figlewicz DA, Orrell RW. The genetics of motor neuron diseases. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 4: 225-31. PMID 14753656 DOI: 10.1080/14660820310011287  0.056
2001 Hadano S, Hand CK, Osuga H, Yanagisawa Y, Otomo A, Devon RS, Miyamoto N, Showguchi-Miyata J, Okada Y, Singaraja R, Figlewicz DA, Kwiatkowski T, Hosler BA, Sagie T, Skaug J, et al. A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2. Nature Genetics. 29: 166-73. PMID 11586298 DOI: 10.1038/Ng1001-166  0.056
2017 Li G, Shofer JB, Petrie EC, Yu CE, Wilkinson CW, Figlewicz DP, Shutes-David A, Zhang J, Montine TJ, Raskind MA, Quinn JF, Galasko DR, Peskind ER. Cerebrospinal fluid biomarkers for Alzheimer's and vascular disease vary by age, gender, and APOE genotype in cognitively normal adults. Alzheimer's Research & Therapy. 9: 48. PMID 28673336 DOI: 10.1186/S13195-017-0271-9  0.056
2001 Williams RE, Cookson MR, Fray AE, Manning PM, Menzies FM, Figlewicz DA, Shaw PJ. Cultured glial cells are resistant to the effects of motor neurone disease-associated SOD1 mutations. Neuroscience Letters. 302: 146-50. PMID 11290408 DOI: 10.1016/S0304-3940(01)01686-X  0.055
2006 Tomik B, Partyka D, SuÅ‚ek A, Kurek-Gryz EA, Banach M, Ostrowska M, Zaremba J, Figlewicz DA, Szczudlik A. A phenotypic-genetic study of a group of Polish patients with spinal and bulbar muscular atrophy. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 7: 72-9. PMID 16753970 DOI: 10.1080/17482960600664839  0.055
2012 Hardiman O, Figlewicz DA. The expansions of ALS. Neurology. 79: 842-3. PMID 22843260 DOI: 10.1212/Wnl.0B013E3182662031  0.055
2004 Slowik A, Borratynska A, Pera J, Betlej M, Dziedzic T, Krzyszkowski T, Czepko R, Figlewicz DA, Szczudlik A. II genotype of the angiotensin-converting enzyme gene increases the risk for subarachnoid hemorrhage from ruptured aneurysm. Stroke; a Journal of Cerebral Circulation. 35: 1594-7. PMID 15166392 DOI: 10.1161/01.STR.0000131655.45227.f7  0.055
1995 Garofalo O, Figlewicz DA, Thomas SM, Butler R, Lebuis L, Rouleau G, Meininger V, Leigh PN. Superoxide dismutase activity in lymphoblastoid cells from motor neurone disease/amyotrophic lateral sclerosis (MND/ALS) patients. Journal of the Neurological Sciences. 129: 90-2. PMID 7595631 DOI: 10.1016/0022-510X(95)00073-B  0.055
1992 Aubry M, Marineau C, Zhang FR, Zahed L, Figlewicz D, Delattre O, Thomas G, de Jong PJ, Julien JP, Rouleau GA. Cloning of six new genes with zinc finger motifs mapping to short and long arms of human acrocentric chromosome 22 (p and q11.2). Genomics. 13: 641-8. PMID 1639391 DOI: 10.1016/0888-7543(92)90135-F  0.054
2008 Meisler MH, Russ C, Montgomery KT, Greenway M, Ennis S, Hardiman O, Figlewicz DA, Quenneville NR, Conibear E, Brown RH. Evaluation of the Golgi trafficking protein VPS54 (wobbler) as a candidate for ALS. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 9: 141-8. PMID 18574757 DOI: 10.1080/17482960801934403  0.052
1997 Parboosingh JS, Figlewicz DA, Krizus A, Meininger V, Azad NA, Newman DS, Rouleau GA. Spinobulbar muscular atrophy can mimic ALS: the importance of genetic testing in male patients with atypical ALS. Neurology. 49: 568-72. PMID 9270598 DOI: 10.1212/Wnl.49.2.568  0.052
2010 Golenia A, Tomik B, Zawislak D, Wolkow P, Dziubek A, Sado M, Szczudlik A, Figlewicz DA, Slowik A. Lack of association between VEGF gene polymorphisms and plasma VEGF levels and sporadic AL. Neurology. 75: 2035-7. PMID 21115961 DOI: 10.1212/WNL.0b013e3181ff9658  0.052
1993 Goto J, Figlewicz DA, Haines JL, Brown RH, Khodr N, Rouleau GA. The glycinamide ribonucleotide transformylase (GART) gene is not responsible for familial amyotrophic lateral sclerosis. Neuromuscular Disorders : Nmd. 3: 157-60. PMID 8358240 DOI: 10.1016/0960-8966(93)90008-8  0.051
1994 Figlewicz DA, Krizus A, Martinoli MG, Meininger V, Dib M, Rouleau GA, Julien JP. Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis. Human Molecular Genetics. 3: 1757-61. PMID 7849698 DOI: 10.1093/Hmg/3.10.1757  0.051
2005 Slowik A, Dziedzic T, Pera J, Figlewicz DA, Szczudlik A. Coagulation factor XIII VaI34Leu polymorphism in patients with small vessel disease or primary intracerebral hemorrhage. Cerebrovascular Diseases (Basel, Switzerland). 19: 165-70. PMID 15644629 DOI: 10.1159/000083251  0.051
1991 Siddique T, Figlewicz DA, Pericak-Vance MA, Haines JL, Rouleau G, Jeffers AJ, Sapp P, Hung WY, Bebout J, McKenna-Yasek D. Linkage of a gene causing familial amyotrophic lateral sclerosis to chromosome 21 and evidence of genetic-locus heterogeneity. The New England Journal of Medicine. 324: 1381-4. PMID 2020294 DOI: 10.1056/Nejm199105163242001  0.051
1996 Rooke K, Figlewicz DA, Han FY, Rouleau GA. Analysis of the KSP repeat of the neurofilament heavy subunit in familiar amyotrophic lateral sclerosis. Neurology. 46: 789-90. PMID 8618684 DOI: 10.1212/Wnl.46.3.789  0.05
2007 Dixit M, Ansseau E, Tassin A, Winokur S, Shi R, Qian H, Sauvage S, Mattéotti C, van Acker AM, Leo O, Figlewicz D, Barro M, Laoudj-Chenivesse D, Belayew A, Coppée F, et al. DUX4, a candidate gene of facioscapulohumeral muscular dystrophy, encodes a transcriptional activator of PITX1. Proceedings of the National Academy of Sciences of the United States of America. 104: 18157-62. PMID 17984056 DOI: 10.1073/Pnas.0708659104  0.05
1993 Rosen DR, Siddique T, Patterson D, Figlewicz DA, Sapp P, Hentati A, Donaldson D, Goto J, O'Regan JP, Deng HX. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature. 362: 59-62. PMID 8446170 DOI: 10.1038/362059a0  0.05
2002 Kriscenski-Perry E, Durham HD, Sheu SS, Figlewicz DA. Synergistic effects of low level stressors in an oxidative damage model of spinal motor neuron degeneration. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 3: 151-7. PMID 12495577 DOI: 10.1080/146608202760834166  0.048
1999 Mithal NP, Radunović A, Figlewicz DA, McMillan TJ, Leigh PN. Cells from individuals with SOD-1 associated familial amyotrophic lateral sclerosis do not have an increased susceptibility to radiation-induced free radical production or DNA damage. Journal of the Neurological Sciences. 164: 89-92. PMID 10385054 DOI: 10.1016/S0022-510X(99)00053-2  0.047
1997 Durham HD, Roy J, Dong L, Figlewicz DA. Aggregation of mutant Cu/Zn superoxide dismutase proteins in a culture model of ALS. Journal of Neuropathology and Experimental Neurology. 56: 523-30. PMID 9143265  0.046
1997 Dubé MP, Mlodzienski MA, Kibar Z, Farlow MR, Ebers G, Harper P, Kolodny EH, Rouleau GA, Figlewicz DA. Hereditary spastic paraplegia: LOD-score considerations for confirmation of linkage in a heterogeneous trait. American Journal of Human Genetics. 60: 625-9. PMID 9042923  0.046
1995 Pramatarova A, Figlewicz DA, Krizus A, Han FY, Ceballos-Picot I, Nicole A, Dib M, Meininger V, Brown RH, Rouleau GA. Identification of new mutations in the Cu/Zn superoxide dismutase gene of patients with familial amyotrophic lateral sclerosis. American Journal of Human Genetics. 56: 592-6. PMID 7887412  0.045
2009 Chow CY, Landers JE, Bergren SK, Sapp PC, Grant AE, Jones JM, Everett L, Lenk GM, McKenna-Yasek DM, Weisman LS, Figlewicz D, Brown RH, Meisler MH. Deleterious variants of FIG4, a phosphoinositide phosphatase, in patients with ALS. American Journal of Human Genetics. 84: 85-8. PMID 19118816 DOI: 10.1016/J.Ajhg.2008.12.010  0.045
1993 Cochius JI, Figlewicz DA, Kälviäinen R, Nousiainen U, Farrell K, Patry G, Söderfeldt B, Frydman M, Lerman P, Andermann F. Unverricht-Lundborg disease: absence of nonallelic genetic heterogeneity. Annals of Neurology. 34: 739-41. PMID 8239570 DOI: 10.1002/Ana.410340519  0.045
2004 Rijkers T, Deidda G, van Koningsbruggen S, van Geel M, Lemmers RJ, van Deutekom JC, Figlewicz D, Hewitt JE, Padberg GW, Frants RR, van der Maarel SM. FRG2, an FSHD candidate gene, is transcriptionally upregulated in differentiating primary myoblast cultures of FSHD patients. Journal of Medical Genetics. 41: 826-36. PMID 15520407 DOI: 10.1136/Jmg.2004.019364  0.043
1995 Parboosingh JS, Rouleau GA, Meninger V, McKenna-Yasek D, Brown RH, Figlewicz DA. Absence of mutations in the Mn superoxide dismutase or catalase genes in familial amyotrophic lateral sclerosis. Neuromuscular Disorders : Nmd. 5: 7-10. PMID 7719145 DOI: 10.1016/0960-8966(94)E0022-Z  0.042
1988 Figlewicz DA, Gremo F, Innocenti GM. Differential expression of neurofilament subunits in the developing corpus callosum. Brain Research. 470: 181-9. PMID 3146406 DOI: 10.1016/0165-3806(88)90236-2  0.042
2009 Ostlund C, Guan T, Figlewicz DA, Hays AP, Worman HJ, Gerace L, Schirmer EC. Reduction of a 4q35-encoded nuclear envelope protein in muscle differentiation. Biochemical and Biophysical Research Communications. 389: 279-83. PMID 19716805 DOI: 10.1016/J.Bbrc.2009.08.133  0.04
2017 Szot P, Franklin A, Figlewicz DP, Beuca TP, Bullock K, Hansen K, Banks WA, Raskind MA, Peskind ER. Multiple lipopolysaccharide (LPS) injections alters interleukin 6 (IL-6), IL-7, IL-10 and IL-6 and IL-7 receptor mRNA in CNS and spleen. Neuroscience. PMID 28456715 DOI: 10.1016/j.neuroscience.2017.04.028  0.04
2013 Chad DA, Bidichandani S, Bruijn L, Capra JD, Dickie B, Ferguson J, Figlewicz D, Forsythe M, Kaufmann P, Kirshner A, Monti W. Funding agencies and disease organizations: resources and recommendations to facilitate ALS clinical research. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 62-6. PMID 23678881 DOI: 10.3109/21678421.2013.778588  0.04
2009 Taborsky GJ, Mei Q, Hackney DJ, Figlewicz DP, LeBoeuf R, Mundinger TO. Loss of islet sympathetic nerves and impairment of glucagon secretion in the NOD mouse: relationship to invasive insulitis. Diabetologia. 52: 2602-11. PMID 19798480 DOI: 10.1007/S00125-009-1494-5  0.038
1994 Hentati A, Bejaoui K, Pericak-Vance MA, Hentati F, Speer MC, Hung WY, Figlewicz DA, Haines J, Rimmler J, Ben Hamida C. Linkage of recessive familial amyotrophic lateral sclerosis to chromosome 2q33-q35. Nature Genetics. 7: 425-8. PMID 7920663 DOI: 10.1038/Ng0794-425  0.037
2000 Figlewicz DA, Dong L, Mlodzienski M, Turcotte JC. Culture models of neurodegenerative disease. Annals of the New York Academy of Sciences. 919: 106-18. PMID 11083103  0.037
2009 Ansseau E, Laoudj-Chenivesse D, Marcowycz A, Tassin A, Vanderplanck C, Sauvage S, Barro M, Mahieu I, Leroy A, Leclercq I, Mainfroid V, Figlewicz D, Mouly V, Butler-Browne G, Belayew A, et al. DUX4c is up-regulated in FSHD. It induces the MYF5 protein and human myoblast proliferation. Plos One. 4: e7482. PMID 19829708 DOI: 10.1371/journal.pone.0007482  0.037
2000 Porte D, Seeley RJ, Woods SC, Baskin DG, Figlewicz DP, Schwartz MW. Comments on the relation among GAD-65, IA-2 antibodies and body adiposity. Diabetologia. 43: 134. PMID 10672457  0.037
1994 Pramatarova A, Goto J, Nanba E, Nakashima K, Takahashi K, Takagi A, Kanazawa I, Figlewicz DA, Rouleau GA. A two basepair deletion in the SOD 1 gene causes familial amyotrophic lateral sclerosis. Human Molecular Genetics. 3: 2061-2. PMID 7874127  0.034
1980 Figlewicz D, Formby B, Hodgeson A. Uptake and distribution of 65zinc in cultured islets Clinical Research. 28: 80A.  0.034
2013 Korngut L, Genge A, Johnston M, Benstead T, Bourque P, Briemberg H, Casey A, D'Amour M, Dupré N, Figlewicz D, Hader W, Johnston W, Kalra S, Melanson M, O'Connell C, et al. Establishing a Canadian registry of patients with amyotrophic lateral sclerosis. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 40: 29-35. PMID 23250124 DOI: 10.1017/S0317167100012919  0.034
2004 Slowik A, Turaj W, Dziedzic T, Haefele A, Pera J, Malecki MT, Glodzik-Sobanska L, Szermer P, Figlewicz DA, Szczudlik A. DD genotype of ACE gene is a risk factor for intracerebral hemorrhage. Neurology. 63: 359-61. PMID 15277638  0.033
2007 Slowik A, Wloch D, Szermer P, Wolkow P, Malecki M, Pera J, Turaj W, Dziedzic T, Klimkowicz-Mrowiec A, Kopec G, Figlewicz DA, Szczudlik A. Paraoxonase 2 gene C311S polymorphism is associated with a risk of large vessel disease stroke in a Polish population. Cerebrovascular Diseases (Basel, Switzerland). 23: 395-400. PMID 17406108 DOI: 10.1159/000101462  0.033
1996 Fink JK, Heiman-Patterson T, Bird T, Cambi F, Dubé MP, Figlewicz DA, Fink JK, Haines JL, Heiman-Patterson T, Hentati A, Pericak-Vance MA, Raskind W, Rouleau GA, Siddique T. Hereditary spastic paraplegia: advances in genetic research. Hereditary Spastic Paraplegia Working group. Neurology. 46: 1507-14. PMID 8649538 DOI: 10.1212/Wnl.46.6.1507  0.032
1994 Figlewicz DA, Garruto RM, Krizus A, Yanagihara R, Rouleau GA. The Cu/Zn superoxide dismutase gene in ALS and parkinsonism-dementia of Guam. Neuroreport. 5: 557-60. PMID 8025243 DOI: 10.1097/00001756-199401000-00006  0.031
1992 Goto J, Figlewicz DA, Marineau C, Khodr N, Rouleau GA. Dinucleotide repeat polymorphism at the IGF2R locus. Nucleic Acids Research. 20: 923. PMID 1311836 DOI: 10.1093/Nar/20.4.923  0.03
1999 Figlewicz DA, Bird TD. "Pure" hereditary spastic paraplegias: the story becomes complicated. Neurology. 53: 5-7. PMID 10408527 DOI: 10.1212/Wnl.53.1.5  0.03
1993 Goto J, Gnirke A, Khodr N, Kaufer E, Krizus A, Figlewicz DA, Rouleau GA. Dinucleotide repeat polymorphism at the D21S370 locus which flanks the PRGS (GARS)-PAIS (AIRS)-PGFT (GART) gene. Human Molecular Genetics. 2: 616. PMID 8518815 DOI: 10.1093/hmg/2.5.616  0.029
1987 Figlewicz DP, Lacour F, Sipols A, Porte D, Woods SC. Gastroenteropancreatic peptides and the central nervous system. Annual Review of Physiology. 49: 383-95. PMID 3551807 DOI: 10.1146/annurev.ph.49.030187.002123  0.029
2004 Saeed M, Slowik A, Borratynska A, Pera J, Dziedzic T, Szczudlik A, Kieltyka A, Figlewicz DA. ACE and subarachnoid hemorrhage: Strategies for genetics of stroke [1] (multiple letters) Stroke. 35: 2752-2753. PMID 15564565  0.028
1991 Brown RH, Horvitz HR, Rouleau GA, McKenna-Yasek D, Beard C, Sapp P, Haines JL, Gusella JF, Figlewicz DA. Gene linkage in familial amyotrophic lateral sclerosis: a progress report. Advances in Neurology. 56: 215-26. PMID 1853758  0.027
1992 Goto J, Figlewicz DA, Gnirke A, Khodr N, Krizus A, Rouleau GA. Dinucleotide repeat polymorphism at the D21S219 locus which flanks the GARS-AIRS-GART gene. Human Molecular Genetics. 1: 782. PMID 1339477 DOI: 10.1093/Hmg/1.9.782  0.027
1995 Griggs RC, Tawil R, McDermott M, Forrester J, Figlewicz D, Weiffenbach B. Monozygotic twins with facioscapulohumeral dystrophy (FSHD): implications for genotype/phenotype correlation. FSH-DY Group. Muscle & Nerve. Supplement. 2: S50-5. PMID 7739626  0.025
1992 Goto J, Tassone F, Demczuk S, Gardiner K, Figlewicz DA, Khodr N, Rouleau GA. Dinucleotide repeat polymorphism at the D21S65 locus. Human Molecular Genetics. 1: 350. PMID 1303216 DOI: 10.1093/Hmg/1.5.350  0.025
1993 Figlewicz DA, Rouleau GA, Krizus A, Julien JP. Polymorphism in the multi-phosphorylation domain of the human neurofilament heavy-subunit-encoding gene. Gene. 132: 297-300. PMID 8224877 DOI: 10.1016/0378-1119(93)90211-K  0.024
2002 Meijer IA, Hand CK, Cossette P, Figlewicz DA, Rouleau GA. Spectrum of SPG4 mutations in a large collection of North American families with hereditary spastic paraplegia. Archives of Neurology. 59: 281-6. PMID 11843700 DOI: 10.1001/Archneur.59.2.281  0.022
2004 Slowik A, Dziedzic T, Turaj W, Pera J, Glodzik-Sobanska L, Szermer P, Malecki MT, Figlewicz DA, Szczudlik A. A2 alelle of GpIIIa gene is a risk factor for stroke caused by large-vessel disease in males. Stroke; a Journal of Cerebral Circulation. 35: 1589-93. PMID 15178823 DOI: 10.1161/01.STR.0000132194.24663.3d  0.022
1985 Figlewicz DA, Nolan CE, Singh IN, Jungalwala FB. Pre-packed reverse phase columns for isolation of complex lipids synthesized from radioactive precursors. Journal of Lipid Research. 26: 140-4. PMID 3973510  0.02
1991 Goto J, Figlewicz DA, Lutchman M, Ruddle F, Rouleau GA. A PvuII RFLP at the HOX 1.4 homeobox locus (HOX1D). Nucleic Acids Research. 19: 3755. PMID 1677186 DOI: 10.1093/Nar/19.13.3755-A  0.02
2001 Figlewicz DA. Neural transplantation therapy: trying the tougher experiment. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 2: 173-4. PMID 11958727 DOI: 10.1080/14660820152882160  0.017
2006 Slowik A, Tomik B, Partyka D, Turaj W, Pera J, Dziedzic T, Szermer P, Figlewicz DA, Szczudlik A. Paraoxonase-1 Q192R polymorphism and risk of sporadic amyotrophic lateral sclerosis. Clinical Genetics. 69: 358-9. PMID 16630171 DOI: 10.1111/j.1399-0004.2006.00590.x  0.017
1995 Griggs RC, Tawil R, McDermott M, Forrester J, Figlewicz D, Weiffenbach B. Monozygotic twins with facioscapulohumeral dystrophy (FSHD): implications for genotype/phenotype correlation. Muscle & Nerve. Supplement. S50-5. PMID 23573587  0.017
2007 Kowaljow V, Marcowycz A, Ansseau E, Conde CB, Sauvage S, Mattéotti C, Arias C, Corona ED, Nuñez NG, Leo O, Wattiez R, Figlewicz D, Laoudj-Chenivesse D, Belayew A, Coppée F, et al. The DUX4 gene at the FSHD1A locus encodes a pro-apoptotic protein. Neuromuscular Disorders : Nmd. 17: 611-23. PMID 17588759 DOI: 10.1016/j.nmd.2007.04.002  0.016
1999 Orrell RW, Tawil R, Forrester J, Kissel JT, Mendell JR, Figlewicz DA. Definitive molecular diagnosis of facioscapulohumeral dystrophy. Neurology. 52: 1822-6. PMID 10371529  0.015
1976 Figlewicz DA, Druce MJ. Incorporation of (3H)leucine into three subfractions of myelin in murine myelin dysgenesis: the quaking mutant. Journal of Neurochemistry. 26: 625-7. PMID 1262883 DOI: 10.1111/J.1471-4159.1976.Tb01523.X  0.014
2008 Figlewicz DA. Comments on Fornai et al. (PNAS/ Feb 2008). Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 9: 125-6. PMID 18428007 DOI: 10.1080/17482960802066643  0.01
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