| Year |
Citation |
Score |
| 2019 |
Skolnick P, Crystal R. Cannabinoid (CB-1) receptor antagonists: a molecular approach to treating acute cannabinoid overdose. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 31893308 DOI: 10.1007/S00702-019-02132-7 |
0.306 |
|
| 2019 |
Krieter PA, Chiang CN, Gyaw S, Skolnick P, Snyder R. Pharmacokinetic Interaction of Naloxone and Naltrexone Following Intranasal Administration to Healthy Subjects. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 30992306 DOI: 10.1124/Dmd.118.085977 |
0.326 |
|
| 2019 |
Krieter P, Gyaw S, Chiang CN, Crystal R, Skolnick P. Enhanced Intranasal Absorption of Naltrexone by Dodecyl Maltopyranoside: Implications for the Treatment of Opioid Overdose. Journal of Clinical Pharmacology. PMID 30698833 DOI: 10.1002/Jcph.1384 |
0.303 |
|
| 2015 |
Skolnick P, Kos T, Czekaj J, Popik P. Effect of NMDAR antagonists in the tetrabenazine test for antidepressants: comparison with the tail suspension test. Acta Neuropsychiatrica. 27: 228-34. PMID 25858023 DOI: 10.1017/Neu.2015.14 |
0.714 |
|
| 2015 |
Popik P, Holuj M, Nikiforuk A, Kos T, Trullas R, Skolnick P. 1-aminocyclopropanecarboxylic acid (ACPC) produces procognitive but not antipsychotic-like effects in rats. Psychopharmacology. 232: 1025-38. PMID 25260339 DOI: 10.1007/S00213-014-3738-4 |
0.794 |
|
| 2014 |
Kim SW, Fowler JS, Skolnick P, Muench L, Kang Y, Shea C, Logan J, Kim D, Carter P, King P, Alexoff D, Volkow ND. Therapeutic doses of buspirone block D3 receptors in the living primate brain – CORRIGENDUM The International Journal of Neuropsychopharmacology. 17: 1354. DOI: 10.1017/S1461145714000881 |
0.308 |
|
| 2013 |
Bergman J, Roof RA, Furman CA, Conroy JL, Mello NK, Sibley DR, Skolnick P. Modification of cocaine self-administration by buspirone (buspar®): potential involvement of D3 and D4 dopamine receptors. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 445-58. PMID 22827916 DOI: 10.1017/S1461145712000661 |
0.34 |
|
| 2012 |
Warnock KT, Yang AR, Yi HS, June HL, Kelly T, Basile AS, Skolnick P, June HL. Amitifadine, a triple monoamine uptake inhibitor, reduces binge drinking and negative affect in an animal model of co-occurring alcoholism and depression symptomatology. Pharmacology, Biochemistry, and Behavior. 103: 111-8. PMID 22884707 DOI: 10.1016/J.Pbb.2012.07.014 |
0.556 |
|
| 2012 |
Newman AH, Blaylock BL, Nader MA, Bergman J, Sibley DR, Skolnick P. Medication discovery for addiction: translating the dopamine D3 receptor hypothesis. Biochemical Pharmacology. 84: 882-90. PMID 22781742 DOI: 10.1016/J.Bcp.2012.06.023 |
0.305 |
|
| 2012 |
Yang AR, Yi HS, Warnock KT, Mamczarz J, June HL, Mallick N, Krieter PA, Tonelli L, Skolnick P, Basile AS, June HL. Effects of the triple monoamine uptake inhibitor DOV 102,677 on alcohol-motivated responding and antidepressant activity in alcohol-preferring (P) rats. Alcoholism, Clinical and Experimental Research. 36: 863-73. PMID 22150508 DOI: 10.1111/J.1530-0277.2011.01671.X |
0.554 |
|
| 2012 |
Tran P, Skolnick P, Czobor P, Huang NY, Bradshaw M, McKinney A, Fava M. Efficacy and tolerability of the novel triple reuptake inhibitor amitifadine in the treatment of patients with major depressive disorder: a randomized, double-blind, placebo-controlled trial. Journal of Psychiatric Research. 46: 64-71. PMID 21925682 DOI: 10.1016/J.Jpsychires.2011.09.003 |
0.511 |
|
| 2010 |
Skolnick P, Popik P, Trullas R. N-methyl-D-aspartate (NMDA) antagonists for the treatment of depression Milestones in Drug Therapy. 1-20. DOI: 10.1007/978-3-0346-0241-9_1 |
0.691 |
|
| 2010 |
FRYER RI, RIOS R, ZHANG P, GU Z, WONG G, BASILE AS, SKOLNICK P. ChemInform Abstract: Structure Activity Relationships of 2-Phenylpyrazolo(4,3-c)quinolin-3- ones and Their N- and O-Methyl Analogues at Benzodiazepine Receptors. Cheminform. 25: no-no. DOI: 10.1002/chin.199414190 |
0.535 |
|
| 2009 |
Skolnick P, Popik P, Trullas R. Glutamate-based antidepressants: 20 years on. Trends in Pharmacological Sciences. 30: 563-9. PMID 19837463 DOI: 10.1016/J.Tips.2009.09.002 |
0.703 |
|
| 2009 |
Nicholson KL, Balster RL, Golembiowska K, Kowalska M, Tizzano JP, Skolnick P, Basile AS. Preclinical evaluation of the abuse potential of the analgesic bicifadine. The Journal of Pharmacology and Experimental Therapeutics. 330: 236-48. PMID 19357320 DOI: 10.1124/Jpet.109.150540 |
0.538 |
|
| 2008 |
Berezhnoy D, Gravielle MC, Downing S, Kostakis E, Basile AS, Skolnick P, Gibbs TT, Farb DH. Pharmacological Properties of DOV 315,090, an ocinaplon metabolite. Bmc Pharmacology. 8: 11. PMID 18554397 DOI: 10.1186/1471-2210-8-11 |
0.596 |
|
| 2008 |
Tizzano JP, Stribling DS, Perez-Tilve D, Strack A, Frassetto A, Chen RZ, Fong TM, Shearman L, Krieter PA, Tschöp MH, Skolnick P, Basile AS. The triple uptake inhibitor (1R,5S)-(+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0] hexane hydrochloride (DOV 21947) reduces body weight and plasma triglycerides in rodent models of diet-induced obesity. The Journal of Pharmacology and Experimental Therapeutics. 324: 1111-26. PMID 18089843 DOI: 10.1124/Jpet.107.133132 |
0.558 |
|
| 2007 |
Skolnick P, Basile AS. Triple reuptake inhibitors ("broad spectrum" antidepressants). Cns & Neurological Disorders Drug Targets. 6: 141-9. PMID 17430151 DOI: 10.2174/187152707780363285 |
0.559 |
|
| 2007 |
Basile AS, Janowsky A, Golembiowska K, Kowalska M, Tam E, Benveniste M, Popik P, Nikiforuk A, Krawczyk M, Nowak G, Krieter PA, Lippa AS, Skolnick P, Koustova E. Characterization of the antinociceptive actions of bicifadine in models of acute, persistent, and chronic pain. The Journal of Pharmacology and Experimental Therapeutics. 321: 1208-25. PMID 17325229 DOI: 10.1124/Jpet.106.116483 |
0.752 |
|
| 2006 |
Popik P, Kostakis E, Krawczyk M, Nowak G, Szewczyk B, Krieter P, Chen Z, Russek SJ, Gibbs TT, Farb DH, Skolnick P, Lippa AS, Basile AS. The anxioselective agent 7-(2-chloropyridin-4-yl)pyrazolo-[1,5-a]-pyrimidin-3-yl](pyridin-2-yl)methanone (DOV 51892) is more efficacious than diazepam at enhancing GABA-gated currents at alpha1 subunit-containing GABAA receptors. The Journal of Pharmacology and Experimental Therapeutics. 319: 1244-52. PMID 16971504 DOI: 10.1124/Jpet.106.107201 |
0.701 |
|
| 2006 |
Skolnick P, Krieter P, Tizzano J, Basile A, Popik P, Czobor P, Lippa A. Preclinical and clinical pharmacology of DOV 216,303, a "triple" reuptake inhibitor. Cns Drug Reviews. 12: 123-34. PMID 16958986 DOI: 10.1111/J.1527-3458.2006.00123.X |
0.691 |
|
| 2006 |
Popik P, Krawczyk M, Golembiowska K, Nowak G, Janowsky A, Skolnick P, Lippa A, Basile AS. Pharmacological profile of the "triple" monoamine neurotransmitter uptake inhibitor, DOV 102,677. Cellular and Molecular Neurobiology. 26: 857-73. PMID 16636898 DOI: 10.1007/S10571-006-9012-5 |
0.711 |
|
| 2006 |
O'Neill MJ, Mackowiak M, Lakics V, Hicks CA, Bleakman D, Skolnick P. The AMPA Receptor Potentiator, LY404187 Modulates Expression of Neurotrophins: in vitro and in vivo Studies in Cortical and Hippocampal Brain Regions Cns Drug Reviews. 10: 193-193. DOI: 10.1111/J.1527-3458.2004.Tb00015.X |
0.339 |
|
| 2006 |
Basile A, Koustova E, Lippa A, Skolnick P. (667) The Journal of Pain. 7: S22. DOI: 10.1016/j.jpain.2006.01.069 |
0.507 |
|
| 2006 |
Koustova E, Basile A, Lippa A, Skolnick P. (666) The Journal of Pain. 7: S22. DOI: 10.1016/j.jpain.2006.01.068 |
0.507 |
|
| 2006 |
Skolnick P, Basile AS. Triple reuptake inhibitors as antidepressants Drug Discovery Today: Therapeutic Strategies. 3: 489-494. DOI: 10.1016/J.Ddstr.2006.10.010 |
0.552 |
|
| 2006 |
Basile AS, Lippa AS, Skolnick P. GABAA receptor modulators as anxioselective anxiolytics Drug Discovery Today: Therapeutic Strategies. 3: 475-481. DOI: 10.1016/J.Ddstr.2006.10.009 |
0.636 |
|
| 2005 |
Lippa A, Czobor P, Stark J, Beer B, Kostakis E, Gravielle M, Bandyopadhyay S, Russek SJ, Gibbs TT, Farb DH, Skolnick P. Selective anxiolysis produced by ocinaplon, a GABA(A) receptor modulator. Proceedings of the National Academy of Sciences of the United States of America. 102: 7380-5. PMID 15870187 DOI: 10.1073/Pnas.0502579102 |
0.333 |
|
| 2004 |
Basile AS, Lippa AS, Skolnick P. Anxioselective anxiolytics: can less be more? European Journal of Pharmacology. 500: 441-51. PMID 15464051 DOI: 10.1016/J.Ejphar.2004.07.043 |
0.614 |
|
| 2004 |
O'Neill MJ, Murray TK, Whalley K, Ward MA, Hicks CA, Woodhouse S, Osborne DJ, Skolnick P. Neurotrophic actions of the novel AMPA receptor potentiator, LY404187, in rodent models of Parkinson's disease. European Journal of Pharmacology. 486: 163-74. PMID 14975705 DOI: 10.1016/J.Ejphar.2003.12.023 |
0.416 |
|
| 2003 |
Paul IA, Skolnick P. Glutamate and depression: clinical and preclinical studies. Annals of the New York Academy of Sciences. 1003: 250-72. PMID 14684451 DOI: 10.1196/Annals.1300.016 |
0.657 |
|
| 2003 |
Skolnick P, Popik P, Janowsky A, Beer B, Lippa AS. "Broad spectrum" antidepressants: is more better for the treatment of depression? Life Sciences. 73: 3175-9. PMID 14561522 DOI: 10.1016/J.Lfs.2003.06.007 |
0.547 |
|
| 2003 |
June HL, Foster KL, McKay PF, Seyoum R, Woods JE, Harvey SC, Eiler WJ, Grey C, Carroll MR, McCane S, Jones CM, Yin W, Mason D, Cummings R, Garcia M, ... ... Skolnick P, et al. The reinforcing properties of alcohol are mediated by GABA(A1) receptors in the ventral pallidum. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 2124-37. PMID 12968126 DOI: 10.1038/Sj.Npp.1300239 |
0.349 |
|
| 2003 |
Li X, Witkin JM, Need AB, Skolnick P. Enhancement of antidepressant potency by a potentiator of AMPA receptors. Cellular and Molecular Neurobiology. 23: 419-30. PMID 12825836 DOI: 10.1023/A:1023648923447 |
0.364 |
|
| 2003 |
Murray TK, Whalley K, Robinson CS, Ward MA, Hicks CA, Lodge D, Vandergriff JL, Baumbarger P, Siuda E, Gates M, Ogden AM, Skolnick P, Zimmerman DM, Nisenbaum ES, Bleakman D, et al. LY503430, a novel alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor potentiator with functional, neuroprotective and neurotrophic effects in rodent models of Parkinson's disease. The Journal of Pharmacology and Experimental Therapeutics. 306: 752-62. PMID 12730350 DOI: 10.1124/Jpet.103.049445 |
0.402 |
|
| 2003 |
Skolnick P, Popik P, Janowsky A, Beer B, Lippa AS. Antidepressant-like actions of DOV 21,947: a "triple" reuptake inhibitor. European Journal of Pharmacology. 461: 99-104. PMID 12586204 DOI: 10.1016/S0014-2999(03)01310-4 |
0.587 |
|
| 2002 |
Quirk JC, Linden AM, Strakhova M, Yu H, Skolnick P, Nisenbaum ES. A single residue contributes sensitivity to allosteric modulation of AMPA receptors by LY395153. European Journal of Pharmacology. 454: 125-9. PMID 12421639 DOI: 10.1016/S0014-2999(02)02491-3 |
0.487 |
|
| 2001 |
Skolnick P. Ibogaine as a glutamate antagonist: relevance to its putative antiaddictive properties. The Alkaloids. Chemistry and Biology. 56: 55-62. PMID 11705116 DOI: 10.1016/S0099-9598(01)56007-1 |
0.404 |
|
| 2001 |
Bai F, Li X, Clay M, Lindstrom T, Skolnick P. Intra- and interstrain differences in models of "behavioral despair". Pharmacology, Biochemistry, and Behavior. 70: 187-92. PMID 11701187 DOI: 10.1016/S0091-3057(01)00599-8 |
0.31 |
|
| 2001 |
Harvey SC, Köster A, Yu H, Skolnick P, Baumbarger P, Nisenbaum ES. AMPA receptor function is altered in GLUR2-deficient mice. Journal of Molecular Neuroscience : Mn. 17: 35-43. PMID 11665861 DOI: 10.1385/Jmn:17:1:35 |
0.48 |
|
| 2001 |
Li X, Tizzano JP, Griffey K, Clay M, Lindstrom T, Skolnick P. Antidepressant-like actions of an AMPA receptor potentiator (LY392098). Neuropharmacology. 40: 1028-33. PMID 11406194 DOI: 10.1016/S0028-3908(00)00194-5 |
0.377 |
|
| 2001 |
Legutko B, Li X, Skolnick P. Regulation of BDNF expression in primary neuron culture by LY392098, a novel AMPA receptor potentiator. Neuropharmacology. 40: 1019-27. PMID 11406193 DOI: 10.1016/S0028-3908(01)00006-5 |
0.331 |
|
| 2001 |
Lindén AM, Yu H, Zarrinmayeh H, Wheeler WJ, Skolnick P. Binding of an AMPA receptor potentiator ([3H]LY395153) to native and recombinant AMPA receptors. Neuropharmacology. 40: 1010-8. PMID 11406192 DOI: 10.1016/S0028-3908(01)00013-2 |
0.475 |
|
| 2000 |
Strakhova MI, Harvey SC, Cook CM, Cook JM, Skolnick P. A single amino acid residue on the alpha(5) subunit (Ile215) is essential for ligand selectivity at alpha(5)beta(3)gamma(2) gamma-aminobutyric acid(A) receptors. Molecular Pharmacology. 58: 1434-40. PMID 11093783 DOI: 10.1124/Mol.58.6.1434 |
0.308 |
|
| 2000 |
Viu E, Zapata A, Capdevila J, Skolnick P, Trullas R. Glycine(B) receptor antagonists and partial agonists prevent memory deficits in inhibitory avoidance learning. Neurobiology of Learning and Memory. 74: 146-60. PMID 10933900 DOI: 10.1006/Nlme.1999.3947 |
0.79 |
|
| 2000 |
Harvey SC, Li X, Skolnick P, Kirst HA. The antibacterial and NMDA receptor activating properties of aminoglycosides are dissociable. European Journal of Pharmacology. 387: 1-7. PMID 10633153 DOI: 10.1016/S0014-2999(99)00798-0 |
0.437 |
|
| 1999 |
Hoo K, Legutko B, Rizkalla G, Deverill M, Hawes CR, Ellis GJ, Stensbol TB, Krogsgaard-Larsen P, Skolnick P, Bleakman D. [3H]ATPA: a high affinity ligand for GluR5 kainate receptors. Neuropharmacology. 38: 1811-7. PMID 10608276 DOI: 10.1016/S0028-3908(99)00133-1 |
0.436 |
|
| 1999 |
Nahum-Levy R, Fossom LH, Skolnick P, Benveniste M. Putative partial agonist 1-aminocyclopropanecarboxylic acid acts concurrently as a glycine-site agonist and a glutamate-site antagonist at N-methyl-D-aspartate receptors. Molecular Pharmacology. 56: 1207-18. PMID 10570048 DOI: 10.1124/Mol.56.6.1207 |
0.436 |
|
| 1999 |
Harvey SC, Skolnick P. Polyamine-like actions of aminoglycosides at recombinant N-methyl-D-aspartate receptors. The Journal of Pharmacology and Experimental Therapeutics. 291: 285-91. PMID 10490915 |
0.314 |
|
| 1999 |
Skolnick P. Antidepressants for the new millennium. European Journal of Pharmacology. 375: 31-40. PMID 10443562 DOI: 10.1016/S0014-2999(99)00330-1 |
0.433 |
|
| 1999 |
Basile AS, Brichta AM, Harris BD, Morse D, Coling D, Skolnick P. Dizocilpine attenuates streptomycin-induced vestibulotoxicity in rats. Neuroscience Letters. 265: 71-4. PMID 10327171 DOI: 10.1016/S0304-3940(99)00050-6 |
0.629 |
|
| 1999 |
Segal JA, Harris BD, Kustova Y, Basile A, Skolnick P. Aminoglycoside neurotoxicity involves NMDA receptor activation. Brain Research. 815: 270-7. PMID 9878779 DOI: 10.1016/S0006-8993(98)01123-8 |
0.637 |
|
| 1999 |
Harris BD, Segal JA, Kustova Y, Basile A, Skolnick P. Aminoglycoside neurotoxicity involves N-methyl-D-aspartate receptor activation Critical Care Medicine. 27: A104. DOI: 10.1097/00003246-199901001-00264 |
0.603 |
|
| 1998 |
Lin Y, Fossom LH, Skolnick P, Long JB. Sustained exposure to a glycine receptor partial agonist differentially alters NMDA receptor agonist and antagonist potencies in cultured spinal cord neurons. European Journal of Pharmacology. 356: 255-60. PMID 9774257 DOI: 10.1016/S0014-2999(98)00515-9 |
0.408 |
|
| 1998 |
Boyer PA, Skolnick P, Fossom LH. Chronic administration of imipramine and citalopram alters the expression of NMDA receptor subunit mRNAs in mouse brain. A quantitative in situ hybridization study. Journal of Molecular Neuroscience : Mn. 10: 219-33. PMID 9770644 DOI: 10.1007/Bf02761776 |
0.648 |
|
| 1998 |
Valeyev AY, Schaffner AE, Skolnick P, Dunlap VS, Wong G, Barker JL. Embryonic rat hippocampal neurons and GABAA receptor subunit-transfected non-neuronal cells release GABA tonically. The Journal of Membrane Biology. 164: 239-51. PMID 9691117 DOI: 10.1007/S002329900409 |
0.504 |
|
| 1998 |
Segal JA, Skolnick P. Polyamine-like actions of aminoglycosides and aminoglycoside derivatives at NMDA receptors. European Journal of Pharmacology. 347: 311-7. PMID 9653898 DOI: 10.1016/S0014-2999(98)00108-3 |
0.421 |
|
| 1998 |
Cox ED, Diaz-Arauzo H, Huang Q, Reddy MS, Ma C, Harris B, McKernan R, Skolnick P, Cook JM. Synthesis and evaluation of analogues of the partial agonist 6-(propyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (6-PBC) and the full agonist 6-(benzyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (Zk 93423) at wild type and recombinant GABAA receptors. Journal of Medicinal Chemistry. 41: 2537-52. PMID 9651158 DOI: 10.1021/Jm970460B |
0.391 |
|
| 1998 |
Sei Y, Kustova Y, Li Y, Morse HC, Skolnick P, Basile AS. The encephalopathy associated with murine acquired immunodeficiency syndrome. Annals of the New York Academy of Sciences. 840: 822-34. PMID 9629308 DOI: 10.1111/J.1749-6632.1998.Tb09620.X |
0.671 |
|
| 1998 |
Granja R, Strakhova M, Knauer CS, Skolnick P. Anomalous rectifying properties of 'diazepam-insensitive' GABA(A) receptors. European Journal of Pharmacology. 345: 315-21. PMID 9592032 DOI: 10.1016/S0014-2999(98)00025-9 |
0.325 |
|
| 1998 |
Viu E, Zapata A, Capdevila JL, Fossom LH, Skolnick P, Trullas R. Glycine site antagonists and partial agonists inhibit N-methyl-D-aspartate receptor-mediated [3H]arachidonic acid release in cerebellar granule cells. The Journal of Pharmacology and Experimental Therapeutics. 285: 527-32. PMID 9580593 |
0.801 |
|
| 1998 |
Nowak G, Legutko B, Skolnick P, Popik P. Adaptation of cortical NMDA receptors by chronic treatment with specific serotonin reuptake inhibitors. European Journal of Pharmacology. 342: 367-70. PMID 9548410 DOI: 10.1016/S0014-2999(97)01589-6 |
0.639 |
|
| 1998 |
Lewin AH, Sun G, Fudala L, Navarro H, Zhou LM, Popik P, Faynsteyn A, Skolnick P. Molecular features associated with polyamine modulation of NMDA receptors. Journal of Medicinal Chemistry. 41: 988-95. PMID 9526573 DOI: 10.1021/Jm9707129 |
0.627 |
|
| 1998 |
Sei Y, Fossom L, Goping G, Skolnick P, Basile AS. Quinolinic acid protects rat cerebellar granule cells from glutamate-induced apoptosis. Neuroscience Letters. 241: 180-4. PMID 9507950 DOI: 10.1016/S0304-3940(97)00980-4 |
0.71 |
|
| 1998 |
Popik P, Skolnick P. Chapter 3 Pharmacology of Ibogaine And Ibogaine-Related Alkaloids Alkaloids: Chemistry and Biology. 52: 197-231. DOI: 10.1016/S0099-9598(08)60027-9 |
0.499 |
|
| 1997 |
Granja R, Gunnersen D, Wong G, Valeyev A, Skolnick P. Diazepam enhancement of GABA-gated currents in binary and ternary GABAA receptors: relationship to benzodiazepine binding site density. Journal of Molecular Neuroscience : Mn. 9: 187-95. PMID 9481620 DOI: 10.1007/Bf02800501 |
0.534 |
|
| 1997 |
Huang NY, Strakhova M, Layer RT, Skolnick P. Chronic antidepressant treatments increase cytochrome b mRNA levels in mouse cerebral cortex. Journal of Molecular Neuroscience : Mn. 9: 167-76. PMID 9481618 DOI: 10.1007/Bf02800499 |
0.751 |
|
| 1997 |
Bovetto S, Boyer P, Skolnick P, Fossom LH. Chronic administration of a glycine partial agonist alters the expression of N-methyl-D-aspartate receptor subunit mRNAs. The Journal of Pharmacology and Experimental Therapeutics. 283: 1503-8. PMID 9400027 |
0.601 |
|
| 1997 |
Zhou LM, Gu ZQ, Costa AM, Yamada KA, Mansson PE, Giordano T, Skolnick P, Jones KA. (2S,4R)-4-methylglutamic acid (SYM 2081): a selective, high-affinity ligand for kainate receptors. The Journal of Pharmacology and Experimental Therapeutics. 280: 422-7. PMID 8996224 |
0.336 |
|
| 1997 |
Laszlo O, Bokonyi G, Szendrei GI, Varga I, Vasko M, Zhou LM, Skolnick P, Maccecchini ML. The flexible termini of conantokin G define its interactions with NMDA receptors International Journal of Peptide Research and Therapeutics. 4: 85-93. DOI: 10.1007/Bf02443519 |
0.695 |
|
| 1996 |
Gunnersen D, Kaufman CM, Skolnick P. Pharmacological properties of recombinant "diazepam-insensitive" GABAA receptors. Neuropharmacology. 35: 1307-14. PMID 9014146 DOI: 10.1016/S0028-3908(96)00054-8 |
0.324 |
|
| 1996 |
Basile AS, Huang JM, Xie C, Webster D, Berlin C, Skolnick P. N-methyl-D-aspartate antagonists limit aminoglycoside antibiotic-induced hearing loss. Nature Medicine. 2: 1338-43. PMID 8946832 DOI: 10.1038/Nm1296-1338 |
0.616 |
|
| 1996 |
Layer RT, Skolnick P, Bertha CM, Bandarage UK, Kuehne ME, Popik P. Structurally modified ibogaine analogs exhibit differing affinities for NMDA receptors. European Journal of Pharmacology. 309: 159-65. PMID 8874134 DOI: 10.1016/0014-2999(96)00304-4 |
0.785 |
|
| 1996 |
Maity R, Mukherjee R, Skolnick P. Stereoselective inhibition of natural killer activity by the sigma ligand (+)-pentazocine. Journal of Neuroimmunology. 70: 7-13. PMID 8862129 DOI: 10.1016/S0165-5728(96)00046-X |
0.387 |
|
| 1996 |
Skolnick P, Layer RT, Popik P, Nowak G, Paul IA, Trullas R. Adaptation of N-methyl-D-aspartate (NMDA) receptors following antidepressant treatment: implications for the pharmacotherapy of depression. Pharmacopsychiatry. 29: 23-6. PMID 8852530 DOI: 10.1055/S-2007-979537 |
0.815 |
|
| 1996 |
Popik P, Skolnick P. The NMDA antagonist memantine blocks the expression and maintenance of morphine dependence. Pharmacology, Biochemistry, and Behavior. 53: 791-7. PMID 8801580 DOI: 10.1016/0091-3057(95)02163-9 |
0.585 |
|
| 1996 |
Sei Y, Whitesell L, Kustova Y, Paul IA, Morse HC, Skolnick P, Basile AS. Altered brain fyn kinase in a murine acquired immunodeficiency syndrome. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 10: 339-44. PMID 8641568 DOI: 10.1096/Fasebj.10.2.8641568 |
0.729 |
|
| 1996 |
Liu R, Hu RJ, Zhang P, Skolnick P, Cook JM. Synthesis and pharmacological properties of novel 8-substituted imidazobenzodiazepines: high-affinity, selective probes for alpha 5-containing GABAA receptors. Journal of Medicinal Chemistry. 39: 1928-34. PMID 8627617 DOI: 10.1021/Jm950887N |
0.388 |
|
| 1996 |
Zhou LM, Szendrei GI, Fossom LH, Maccecchini ML, Skolnick P, Otvos L. Synthetic analogues of conantokin-G: NMDA antagonists acting through a novel polyamine-coupled site. Journal of Neurochemistry. 66: 620-8. PMID 8592132 DOI: 10.1046/J.1471-4159.1996.66020620.X |
0.393 |
|
| 1996 |
Nishida K, Markey SP, Kustova Y, Morse HC, Skolnick P, Basile AS, Sei Y. Increased brain levels of platelet-activating factor in a murine acquired immune deficiency syndrome are NMDA receptor-mediated. Journal of Neurochemistry. 66: 433-5. PMID 8522986 DOI: 10.1046/J.1471-4159.1996.66010433.X |
0.691 |
|
| 1996 |
Sei Y, Paul IA, Saito K, Layar R, Hartley JW, Morse HC, Skolnick P, Heyes MP. Quinolinic acid levels in a murine retrovirus-induced immunodeficiency syndrome. Journal of Neurochemistry. 66: 296-302. PMID 8522967 DOI: 10.1046/J.1471-4159.1996.66010296.X |
0.673 |
|
| 1995 |
Fossom LH, Basile AS, Skolnick P. Sustained exposure to 1-aminocyclopropanecarboxylic acid, a glycine partial agonist, alters N-methyl-D-aspartate receptor function and subunit composition. Molecular Pharmacology. 48: 981-7. PMID 8848014 |
0.599 |
|
| 1995 |
Popik P, Lewin A, Berrang B, Nowak G, Layer R, Skolnick P. [3H]1-aminocyclopropanecarboxylic acid, a novel probe for strychnine- insensitive glycine receptors. European Journal of Pharmacology. 291: 221-7. PMID 8719405 DOI: 10.1016/0922-4106(95)90061-6 |
0.789 |
|
| 1995 |
Layer RT, Popik P, Olds T, Skolnick P. Antidepressant-like actions of the polyamine site NMDA antagonist, eliprodil (SL-82.0715). Pharmacology, Biochemistry, and Behavior. 52: 621-7. PMID 8545484 DOI: 10.1016/0091-3057(95)00155-P |
0.809 |
|
| 1995 |
Harris BD, Wong G, Moody EJ, Skolnick P. Different subunit requirements for volatile and nonvolatile anesthetics at gamma-aminobutyric acid type A receptors. Molecular Pharmacology. 47: 363-7. PMID 7870045 |
0.507 |
|
| 1995 |
Sei Y, Takemura M, Gusovsky F, Skolnick P, Basile A. Distinct mechanisms for Ca2+ entry induced by OKT3 and Ca2+ depletion in Jurkat T cells. Experimental Cell Research. 216: 222-31. PMID 7813624 DOI: 10.1006/Excr.1995.1028 |
0.66 |
|
| 1995 |
Maity R, Mukherjee R, Skolnick P. Morphine inhibits the development of allogeneic immune responses in mouse lymph node. Immunopharmacology. 29: 175-83. PMID 7775160 DOI: 10.1016/0162-3109(94)00058-N |
0.305 |
|
| 1995 |
Zhang P, Zhang W, Liu R, Harris B, Skolnick P, Cook JM. Synthesis of novel imidazobenzodiazepines as probes of the pharmacophore for "diazepam-insensitive" GABAA receptors. Journal of Medicinal Chemistry. 38: 1679-88. PMID 7752192 DOI: 10.1021/Jm00010A013 |
0.425 |
|
| 1995 |
Gu ZQ, Hesson DP, Pelletier JC, Maccecchini ML, Zhou LM, Skolnick P. Synthesis, resolution, and biological evaluation of the four stereoisomers of 4-methylglutamic acid: selective probes of kainate receptors. Journal of Medicinal Chemistry. 38: 2518-20. PMID 7629789 DOI: 10.1021/Jm00014A002 |
0.67 |
|
| 1995 |
Popik P, Layer RT, Skolnick P. 100 years of ibogaine: neurochemical and pharmacological actions of a putative anti-addictive drug. Pharmacological Reviews. 47: 235-53. PMID 7568327 |
0.722 |
|
| 1995 |
Harris BD, Moody EJ, Gu ZQ, Skolnick P. Contribution of "diazepam-insensitive" GABAA receptors to the alcohol antagonist properties of Ro 15-4513 and related imidazobenzodiazepines. Pharmacology, Biochemistry, and Behavior. 52: 113-8. PMID 7501652 DOI: 10.1016/0091-3057(95)00052-X |
0.351 |
|
| 1995 |
Fossom LH, Skolnick P. Sensitization and desensitization of the NMDA receptor complex. Implications for therapy. Annals of the New York Academy of Sciences. 765: 320-1. PMID 7486630 DOI: 10.1111/J.1749-6632.1995.Tb16601.X |
0.349 |
|
| 1995 |
Fossom LH, Von Lubitz DK, Lin RC, Skolnick P. Neuroprotective actions of 1-aminocyclopropanecarboxylic acid (ACPC): a partial agonist at strychnine-insensitive glycine sites. Neurological Research. 17: 265-9. PMID 7477740 DOI: 10.1080/01616412.1995.11740324 |
0.414 |
|
| 1995 |
Popik P, Layer RT, Fossom LH, Benveniste M, Geter-Douglass B, Witkin JM, Skolnick P. NMDA antagonist properties of the putative antiaddictive drug, ibogaine. The Journal of Pharmacology and Experimental Therapeutics. 275: 753-60. PMID 7473163 |
0.79 |
|
| 1995 |
Zhang W, Liu R, Huang Q, Zhang P, Koehler KF, Harris B, Skolnick P, Cook JM. Syntheses of 5-thienyl and 5-furyl-substituted benzodiazepines: probes of the pharmacophore for benzodiazepine receptor agonists European Journal of Medicinal Chemistry. 30: 483-496. DOI: 10.1016/0223-5234(96)88259-6 |
0.342 |
|
| 1994 |
Paul IA, Nowak G, Layer RT, Popik P, Skolnick P. Adaptation of the N-methyl-D-aspartate receptor complex following chronic antidepressant treatments. The Journal of Pharmacology and Experimental Therapeutics. 269: 95-102. PMID 8169857 |
0.813 |
|
| 1994 |
Zhang W, Koehler KF, Harris B, Skolnick P, Cook JM. Synthesis of benzo-fused benzodiazepines employed as probes of the agonist pharmacophore of benzodiazepine receptors. Journal of Medicinal Chemistry. 37: 745-57. PMID 8145224 DOI: 10.1021/Jm00032A007 |
0.333 |
|
| 1994 |
Harris BD, Moody EJ, Basile AS, Skolnick P. Volatile anesthetics bidirectionally and stereospecifically modulate ligand binding to GABA receptors. European Journal of Pharmacology. 267: 269-74. PMID 8088365 DOI: 10.1016/0922-4106(94)90150-3 |
0.655 |
|
| 1994 |
Sei Y, Von Lubitz KJ, Basile AS, Borner MM, Lin RC, Skolnick P, Fossom LH. Internucleosomal DNA fragmentation in gerbil hippocampus following forebrain ischemia. Neuroscience Letters. 171: 179-82. PMID 8084486 DOI: 10.1016/0304-3940(94)90634-3 |
0.648 |
|
| 1994 |
Faiman CP, Viu E, Skolnick P, Trullas R. Differential effects of compounds that act at strychnine-insensitive glycine receptors in a punishment procedure. The Journal of Pharmacology and Experimental Therapeutics. 270: 528-33. PMID 8071846 |
0.796 |
|
| 1994 |
Moody EJ, Harris B, Hoehner P, Skolnick P. Inhibition of [3H]isradipine binding to L-type calcium channels by the optical isomers of isoflurane. Lack of stereospecificity. Anesthesiology. 81: 124-8. PMID 8042780 DOI: 10.1097/00000542-199407000-00018 |
0.301 |
|
| 1994 |
Berger P, Farrel K, Sharp F, Skolnick P. Drugs acting at the strychnine-insensitive glycine receptor do not induce HSP-70 protein in the cingulate cortex. Neuroscience Letters. 168: 147-50. PMID 8028768 DOI: 10.1016/0304-3940(94)90437-5 |
0.361 |
|
| 1994 |
Long JB, Skolnick P. 1-Aminocyclopropanecarboxylic acid protects against dynorphin A-induced spinal injury. European Journal of Pharmacology. 261: 295-301. PMID 7813551 DOI: 10.1016/0014-2999(94)90120-1 |
0.418 |
|
| 1994 |
Wong G, Lyon T, Skolnick P. Chronic exposure to benzodiazepine receptor ligands uncouples the gamma-aminobutyric acid type A receptor in WSS-1 cells. Molecular Pharmacology. 46: 1056-62. PMID 7808424 |
0.531 |
|
| 1994 |
Popik P, Layer RT, Skolnick P. The putative anti-addictive drug ibogaine is a competitive inhibitor of [3H]MK-801 binding to the NMDA receptor complex. Psychopharmacology. 114: 672-4. PMID 7531855 DOI: 10.1007/Bf02245000 |
0.797 |
|
| 1994 |
Moody EJ, Harris BD, Wong G, Skolnick P. Effects Of Subunit Composition On Isoflurane Action At Cloned Gabaa Receptors Anesthesiology. 81. DOI: 10.1097/00000542-199409001-00470 |
0.368 |
|
| 1994 |
Lewin AH, Lamb PB, Popik P, Skolnick P. One-step preparation of [2,3-3H]-aminocyclo- propanecarboxylic acid: A useful ligand for strychnine-insensitive glycine receptors Journal of Labelled Compounds and Radiopharmaceuticals. 34: 1063-1068. DOI: 10.1002/Jlcr.2580341109 |
0.617 |
|
| 1994 |
He X, Matecka D, Lee KS, Gu ZQ, Rice KC, Wong G, Skolnick P, De Costa BR. Synthesis of [123I]tert-butyl 8-iodo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine 3-carboxylate, a potential SPECT imaging agent for diazepam-insensitive (DI) benzodiazepine receptors Journal of Labelled Compounds and Radiopharmaceuticals. 34: 27-32. DOI: 10.1002/Jlcr.2580340105 |
0.549 |
|
| 1994 |
Wong G, Lyon T, Skolnick P. Chronic exposure to benzodiazepine receptor ligands uncouples the γ- aminobutyric acid type A receptor in WSS-1 cells Molecular Pharmacology. 46: 1056-1062. |
0.505 |
|
| 1993 |
Moody EJ, Harris BD, Skolnick P. Stereospecific actions of the inhalation anesthetic isoflurane at the GABAA receptor complex. Brain Research. 615: 101-6. PMID 8395953 DOI: 10.1016/0006-8993(93)91119-D |
0.441 |
|
| 1993 |
Wong G, Skolnick P, Katz JL, Witkin JM. Transduction of a discriminative stimulus through a diazepam-insensitive gamma-aminobutyric acidA receptor. The Journal of Pharmacology and Experimental Therapeutics. 266: 570-6. PMID 8394910 |
0.538 |
|
| 1993 |
Wong G, Koehler KF, Skolnick P, Gu ZQ, Ananthan S, Schönholzer P, Hunkeler W, Zhang W, Cook JM. Synthetic and computer-assisted analysis of the structural requirements for selective, high-affinity ligand binding to diazepam-insensitive benzodiazepine receptors. Journal of Medicinal Chemistry. 36: 1820-30. PMID 8390574 DOI: 10.1021/Jm00065A004 |
0.543 |
|
| 1993 |
Harris B, Wong G, Skolnick P. Neurochemical actions of inhalational anesthetics at the GABAA receptor complex. The Journal of Pharmacology and Experimental Therapeutics. 265: 1392-8. PMID 8389865 |
0.561 |
|
| 1993 |
Fryer RI, Zhang P, Rios R, Gu ZQ, Basile AS, Skolnick P. Structure-activity relationship studies at the benzodiazepine receptor (BZR): a comparison of the substitutent effects of pyrazoloquinolinone analogs. Journal of Medicinal Chemistry. 36: 1669-73. PMID 8388472 DOI: 10.1021/Jm00063A017 |
0.626 |
|
| 1993 |
Gu ZQ, Wong G, Dominguez C, de Costa BR, Rice KC, Skolnick P. Synthesis and evaluation of imidazo[1,5-a][1,4]benzodiazepine esters with high affinities and selectivities at "diazepam-insensitive" benzodiazepine receptors. Journal of Medicinal Chemistry. 36: 1001-6. PMID 8386769 DOI: 10.1021/Jm00060A007 |
0.477 |
|
| 1993 |
Ananthan S, Clayton SD, Ealick SE, Wong G, Evoniuk GE, Skolnick P. Synthesis and structure-activity relationships of 3,5-disubstituted 4,5-dihydro-6H-imidazo[1,5-a][1,4]benzodiazepin-6-ones at diazepam-sensitive and diazepam-insensitive benzodiazepine receptors. Journal of Medicinal Chemistry. 36: 479-90. PMID 8386247 DOI: 10.1021/Jm00056A008 |
0.555 |
|
| 1993 |
Paul IA, Basile AS, Rojas E, Youdim MB, De Costa B, Skolnick P, Pollard HB, Kuijpers GA. Sigma receptors modulate nicotinic receptor function in adrenal chromaffin cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 7: 1171-8. PMID 8375616 DOI: 10.1096/Fasebj.7.12.8375616 |
0.742 |
|
| 1993 |
Wong G, Gu ZQ, de Costa B, Skolnick P. Labelling of diazepam-sensitive and -insensitive benzodiazepine receptors with [3H]tert-butyl-8-chloro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo [1,5-a][1,4]benzodiazepine 3-carboxylate (ZG-63). European Journal of Pharmacology. 247: 57-63. PMID 8258361 DOI: 10.1016/0922-4106(93)90137-X |
0.609 |
|
| 1993 |
Nowak G, Paul IA, Popik P, Young A, Skolnick P. Ca2+ antagonists effect an antidepressant-like adaptation of the NMDA receptor complex. European Journal of Pharmacology. 247: 101-2. PMID 8258355 DOI: 10.1016/0922-4106(93)90144-X |
0.754 |
|
| 1993 |
Lewin AH, Skolnick P, Marvizon JC, Paul IA, Bowen JP. Requirements for high affinity binding of glycine analogs to the glycine site of the NMDA receptor complex. European Journal of Pharmacology. 247: 1-10. PMID 8258354 DOI: 10.1016/0922-4106(93)90131-R |
0.614 |
|
| 1993 |
Layer RT, Bland LR, Skolnick P. MK-801, but not drugs acting at strychnine-insensitive glycine receptors, attenuate methamphetamine nigrostriatal toxicity. Brain Research. 625: 38-44. PMID 8242398 DOI: 10.1016/0006-8993(93)90135-A |
0.766 |
|
| 1993 |
Fride E, McIntyre T, Skolnick P, Arora PK. Immunocompetence in the long sleep and short sleep mouse lines: baseline versus primed responses. Brain, Behavior, and Immunity. 7: 231-42. PMID 8219412 DOI: 10.1006/Brbi.1993.1024 |
0.774 |
|
| 1993 |
Nowak G, Trullas R, Layer RT, Skolnick P, Paul IA. Adaptive changes in the N-methyl-D-aspartate receptor complex after chronic treatment with imipramine and 1-aminocyclopropanecarboxylic acid. The Journal of Pharmacology and Experimental Therapeutics. 265: 1380-6. PMID 8099620 |
0.83 |
|
| 1993 |
Boje KM, Wong G, Skolnick P. Desensitization of the NMDA receptor complex by glycinergic ligands in cerebellar granule cell cultures. Brain Research. 603: 207-14. PMID 8096423 DOI: 10.1016/0006-8993(93)91239-O |
0.592 |
|
| 1993 |
Paul IA, Layer RT, Skolnick P, Nowak G. Adaptation of the NMDA receptor in rat cortex following chronic electroconvulsive shock or imipramine. European Journal of Pharmacology. 247: 305-11. PMID 7905831 DOI: 10.1016/0922-4106(93)90199-J |
0.825 |
|
| 1993 |
Trullas R, Skolnick P. Differences in fear motivated behaviors among inbred mouse strains. Psychopharmacology. 111: 323-31. PMID 7870970 DOI: 10.1007/Bf02244948 |
0.586 |
|
| 1993 |
Gu ZQ, Wong G, Skolnick P, Rice KC. Synthesis and biological evaluation of novel GABA(A)/benzodiazepine receptor ligands selective for the diazepam insensitive (DI) subtype Nida Research Monograph Series. 385. |
0.484 |
|
| 1992 |
McCabe RT, Skolnick P, Jacobson KA. 2-[2-[4-[2-[2-[ 1,3-Dihydro- 1,1-bis (4-hydroxyphenyl)-3-oxo-5-isobenzofuranthioureidyl]ethylaminocarbonyl]ethyl]phenyl] ethylamino]-5'-N-ethylcarboxamidoadenosine (FITC-APEC): A Fluorescent Ligand For A2a-Adenosine Receptors. Journal of Fluorescence. 2: 217-223. PMID 23772170 DOI: 10.1007/Bf00865279 |
0.376 |
|
| 1992 |
Sei Y, Arora PK, Skolnick P, Paul IA. Spatial learning impairment in a murine model of AIDS. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 6: 3008-13. PMID 1644264 DOI: 10.1096/Fasebj.6.11.1644264 |
0.665 |
|
| 1992 |
Skolnick P, Miller R, Young A, Boje K, Trullas R. Chronic treatment with 1-aminocyclopropanecarboxylic acid desensitizes behavioral responses to compounds acting at the N-methyl-D-aspartate receptor complex. Psychopharmacology. 107: 489-96. PMID 1534910 DOI: 10.1007/Bf02245261 |
0.686 |
|
| 1992 |
Boje KM, Skolnick P. Ontogeny of glycine-enhanced [3H]MK-801 binding to N-methyl-D-aspartate receptor-coupled ion channels. Brain Research. Developmental Brain Research. 65: 51-6. PMID 1372541 DOI: 10.1016/0165-3806(92)90007-J |
0.426 |
|
| 1992 |
Sei Y, McIntyre T, Skolnick P, Arora PK. Ethanol inhibits mitogen-induced calcium mobilization in mouse splenocytes. Life Sciences. 50: 419-26. PMID 1346466 DOI: 10.1016/0024-3205(92)90376-Z |
0.771 |
|
| 1992 |
Sei Y, Skolnick P, Arora PK. Strain variation in immune response and behavior following the death of cage cohorts. The International Journal of Neuroscience. 65: 247-58. PMID 1341687 DOI: 10.3109/00207459209003298 |
0.52 |
|
| 1992 |
Boje KM, Skolnick P, Raber J, Fletcher RT, Chader G. Strychnine-insensitive glycine receptors in embryonic chick retina: characteristics and modulation of NMDA neurotoxicity. Neurochemistry International. 20: 473-86. PMID 1339019 DOI: 10.1016/0197-0186(92)90026-N |
0.316 |
|
| 1992 |
Wong G, Sei Y, Skolnick P. Stable expression of type I gamma-aminobutyric acidA/benzodiazepine receptors in a transfected cell line. Molecular Pharmacology. 42: 996-1003. PMID 1336119 |
0.654 |
|
| 1992 |
Skolnick P, Boje K, Miller R, Pennington M, Maccecchini ML. Noncompetitive inhibition of N-methyl-D-aspartate by conantokin-G: evidence for an allosteric interaction at polyamine sites. Journal of Neurochemistry. 59: 1516-21. PMID 1328523 DOI: 10.1111/J.1471-4159.1992.Tb08468.X |
0.395 |
|
| 1992 |
Von Lubitz DK, Lin RC, McKenzie RJ, Devlin TM, McCabe RT, Skolnick P. A novel treatment of global cerebral ischaemia with a glycine partial agonist. European Journal of Pharmacology. 219: 153-8. PMID 1327834 |
0.325 |
|
| 1992 |
Wong G, Skolnick P. Ro 15-4513 binding to GABAA receptors: subunit composition determines ligand efficacy. Pharmacology, Biochemistry, and Behavior. 42: 107-10. PMID 1326771 DOI: 10.1016/0091-3057(92)90454-N |
0.578 |
|
| 1992 |
Chang YJ, McCabe RT, Rennert H, Budarf ML, Sayegh R, Emanuel BS, Skolnick P, Strauss JF. The human "peripheral-type" benzodiazepine receptor: regional mapping of the gene and characterization of the receptor expressed from cDNA. Dna and Cell Biology. 11: 471-80. PMID 1326278 DOI: 10.1089/Dna.1992.11.471 |
0.313 |
|
| 1992 |
Fride E, Meng R, Skolnick P, Arora PK. Immunoenhancing effects of alprazolam, a benzodiazepine receptor agonist. Annals of the New York Academy of Sciences. 650: 132-9. PMID 1318653 DOI: 10.1111/J.1749-6632.1992.Tb49110.X |
0.794 |
|
| 1992 |
Paul IA, Trullas R, Skolnick P, Nowak G. Down-regulation of cortical beta-adrenoceptors by chronic treatment with functional NMDA antagonists. Psychopharmacology. 106: 285-7. PMID 1312732 DOI: 10.1007/Bf02801986 |
0.757 |
|
| 1992 |
Wong G, Skolnick P. High affinity ligands for 'diazepam-insensitive' benzodiazepine receptors. European Journal of Pharmacology. 225: 63-8. PMID 1311690 DOI: 10.1016/0922-4106(92)90040-3 |
0.59 |
|
| 1992 |
Allen MS, Skolnick P, Cook JM. Synthesis of novel 2-phenyl-2H-pyrazolo[4,3-c]isoquinolin-3-ols: topological comparisons with analogues of 2-phenyl-2,5-dihydropyrazolo[4,3-c]quinolin-3(3H)-ones at benzodiazepine receptors. Journal of Medicinal Chemistry. 35: 368-74. PMID 1310121 DOI: 10.1021/Jm00080A024 |
0.321 |
|
| 1992 |
Harris B, Wong G, Skolnick P. Volatile Anesthetics And Barbiturates Exhibit Neurochemical Similarities At Gabaa Receptors Anesthesiology. 77. DOI: 10.1097/00000542-199209001-00697 |
0.406 |
|
| 1992 |
Gu ZQ, De Costa BR, Wong G, Rice KC, Skolnick P. Synthesis of [3H]tert-butyl 8-chloro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4-benzodiazepi ne 3-carboxylate, a selective, high affinity ligand for the diazepam insensitive (DI) subtype of the benzodiazepine receptor Journal of Labelled Compounds and Radiopharmaceuticals. 31: 1049-1055. DOI: 10.1002/Jlcr.2580311213 |
0.552 |
|
| 1991 |
de Costa BR, Lewin AH, Rice KC, Skolnick P, Schoenheimer JA. Novel site-directed affinity ligands for GABA-gated chloride channels: synthesis, characterization, and molecular modeling of 1-(isothiocyanatophenyl)-4-tert-butyl-2,6,7-trioxabicyclo[2.2.2]octanes . Journal of Medicinal Chemistry. 34: 1531-8. PMID 2033577 DOI: 10.1021/Jm00109A002 |
0.332 |
|
| 1991 |
Sei Y, McIntyre T, Fride E, Yoshimoto K, Skolnick P, Arora PK. Inhibition of calcium mobilization is an early event in opiate-induced immunosuppression. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 5: 2194-9. PMID 2022315 DOI: 10.1096/Fasebj.5.8.2022315 |
0.77 |
|
| 1991 |
Sei Y, McIntyre T, Skolnick P, Arora PK. Stress modulates calcium mobilization in immune cells. Life Sciences. 49: 671-6. PMID 1865761 DOI: 10.1016/0024-3205(91)90114-Q |
0.764 |
|
| 1991 |
McIntyre T, Skolnick P. t-[35S]butylbicyclophosphorothionate binding under equilibrium and nonequilibrium conditions: differential effects of barbiturates and gamma-aminobutyric acid in the long-sleep and short-sleep selected mouse lines. Journal of Neurochemistry. 56: 287-93. PMID 1846173 DOI: 10.1111/J.1471-4159.1991.Tb02594.X |
0.748 |
|
| 1991 |
Nowak G, Skolnick P, Paul IA. Down-regulation of dopamine1 (D1) receptors by chronic imipramine is species-specific. Pharmacology, Biochemistry, and Behavior. 39: 769-71. PMID 1838413 DOI: 10.1016/0091-3057(91)90162-U |
0.64 |
|
| 1991 |
Sei Y, Yoshimoto K, McIntyre T, Skolnick P, Arora PK. Morphine-induced thymic hypoplasia is glucocorticoid-dependent. Journal of Immunology (Baltimore, Md. : 1950). 146: 194-8. PMID 1824589 |
0.751 |
|
| 1991 |
Moody EJ, Lewin AH, de Costa BR, Rice KC, Skolnick P. Site-specific acylation of GABA-gated Cl- channels: effects on 36Cl- uptake. European Journal of Pharmacology. 206: 113-8. PMID 1712308 DOI: 10.1016/0922-4106(91)90019-E |
0.351 |
|
| 1991 |
Trullas R, Folio T, Young A, Miller R, Boje K, Skolnick P. 1-aminocyclopropanecarboxylates exhibit antidepressant and anxiolytic actions in animal models. European Journal of Pharmacology. 203: 379-85. PMID 1685448 DOI: 10.1016/0014-2999(91)90894-V |
0.658 |
|
| 1991 |
Basile AS, Jones EA, Skolnick P. The pathogenesis and treatment of hepatic encephalopathy: evidence for the involvement of benzodiazepine receptor ligands. Pharmacological Reviews. 43: 27-71. PMID 1674609 |
0.556 |
|
| 1991 |
Diaz-Arauzo H, Evoniuk GE, Skolnick P, Cook JM. The agonist pharmacophore of the benzodiazepine receptor. Synthesis of a selective anticonvulsant/anxiolytic. Journal of Medicinal Chemistry. 34: 1754-6. PMID 1674542 DOI: 10.1021/Jm00109A035 |
0.342 |
|
| 1991 |
Evoniuk GE, Hertzman RP, Skolnick P. A rapid method for evaluating the behavioral effects of phencyclidine-like dissociative anesthetics in mice. Psychopharmacology. 105: 125-8. PMID 1660607 DOI: 10.1007/Bf02316874 |
0.437 |
|
| 1991 |
Arora PK, Hanna EE, Skolnick P. Suppression of cytotoxic T lymphocyte (CTL) activity by FG 7142, a benzodiazepine receptor 'inverse agonist'. Immunopharmacology. 21: 91-7. PMID 1652574 DOI: 10.1016/0162-3109(91)90012-N |
0.43 |
|
| 1991 |
Basile AS, Hughes RD, Harrison PM, Murata Y, Pannell L, Jones EA, Williams R, Skolnick P. Elevated brain concentrations of 1,4-benzodiazepines in fulminant hepatic failure. The New England Journal of Medicine. 325: 473-8. PMID 1649403 DOI: 10.1097/00132586-199202000-00006 |
0.605 |
|
| 1991 |
Trullas R, Skolnick P. Glycine antagonists and partial agonists as novel anxiolytic/antidepressant agents European Neuropsychopharmacology. 1: 205-207. DOI: 10.1016/0924-977X(91)90486-E |
0.617 |
|
| 1990 |
Petitto JM, McIntyre TD, McRae BL, Skolnick P, Arora PK. Differential immune responsiveness in mouse lines selectively bred for high and low sensitivity to ethanol. Brain, Behavior, and Immunity. 4: 39-49. PMID 2334815 DOI: 10.1016/0889-1591(90)90005-B |
0.722 |
|
| 1990 |
Fride E, Skolnick P, Arora PK. Immunoenhancing effects of alprazolam in mice. Life Sciences. 47: 2409-20. PMID 2175825 DOI: 10.1016/0024-3205(90)90485-A |
0.785 |
|
| 1990 |
Trullas R, Skolnick P. Functional antagonists at the NMDA receptor complex exhibit antidepressant actions. European Journal of Pharmacology. 185: 1-10. PMID 2171955 DOI: 10.1016/0014-2999(90)90204-J |
0.685 |
|
| 1990 |
Trudell ML, Lifer SL, Tan YC, Martin MJ, Deng L, Skolnick P, Cook JM. Synthesis of substituted 7,12-dihydropyrido[3,2-b:5,4-b']diindoles: rigid planar benzodiazepine receptor ligands with inverse agonist/antagonist properties. Journal of Medicinal Chemistry. 33: 2412-20. PMID 2167978 DOI: 10.1021/Jm00171A015 |
0.345 |
|
| 1990 |
Gammal SH, Basile AS, Geller D, Skolnick P, Jones EA. Reversal of the behavioral and electrophysiological abnormalities of an animal model of hepatic encephalopathy by benzodiazepine receptor ligands. Hepatology (Baltimore, Md.). 11: 371-8. PMID 2155865 DOI: 10.1002/Hep.1840110307 |
0.604 |
|
| 1990 |
Marvizón JC, Skolnick P. An endogenous modulator of N-methyl-D-aspartate receptor-coupled glycine receptors. European Journal of Pharmacology. 188: 23-32. PMID 2155119 DOI: 10.1016/0922-4106(90)90244-R |
0.438 |
|
| 1990 |
Basile AS, Ostrowski NL, Gammal SH, Jones EA, Skolnick P. The GABAA receptor complex in hepatic encephalopathy. Autoradiographic evidence for the presence of elevated levels of a benzodiazepine receptor ligand. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 3: 61-71. PMID 2154999 |
0.609 |
|
| 1990 |
Fride E, Collins RL, Skolnick P, Arora PK. Strain-dependent association between immune function and paw preference in mice. Brain Research. 522: 246-50. PMID 2146001 DOI: 10.1016/0006-8993(90)91468-V |
0.743 |
|
| 1990 |
Fride E, Collins RL, Skolnick P, Arora PK. Immune function in lines of mice selected for high or low degrees of behavioral asymmetry. Brain, Behavior, and Immunity. 4: 129-38. PMID 2144194 DOI: 10.1016/0889-1591(90)90015-I |
0.756 |
|
| 1990 |
Arora PK, Fride E, Petitto J, Waggie K, Skolnick P. Morphine-induced immune alterations in vivo. Cellular Immunology. 126: 343-53. PMID 2107031 DOI: 10.1016/0008-8749(90)90326-M |
0.746 |
|
| 1990 |
Paul IA, Kuypers G, Youdim M, Skolnick P. Polyamines non-competitively inhibit [3H]3-PPP binding to sigma receptors. European Journal of Pharmacology. 184: 203-4. PMID 1976528 DOI: 10.1016/0014-2999(90)90685-Y |
0.662 |
|
| 1990 |
Basile AS, Pannell L, Jaouni T, Gammal SH, Fales HM, Jones EA, Skolnick P. Brain concentrations of benzodiazepines are elevated in an animal model of hepatic encephalopathy. Proceedings of the National Academy of Sciences of the United States of America. 87: 5263-7. PMID 1973539 DOI: 10.1073/Pnas.87.14.5263 |
0.59 |
|
| 1990 |
Hollinshead SP, Trudell ML, Skolnick P, Cook JM. Structural requirements for agonist actions at the benzodiazepine receptor: studies with analogues of 6-(benzyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester. Journal of Medicinal Chemistry. 33: 1062-9. PMID 1968513 DOI: 10.1021/Jm00165A028 |
0.335 |
|
| 1990 |
Jones EA, Basile AS, Skolnick P. Hepatic encephalopathy, GABA-ergic neurotransmission and benzodiazepine receptor ligands. Advances in Experimental Medicine and Biology. 272: 121-34. PMID 1966504 DOI: 10.1007/978-1-4684-5826-8_7 |
0.634 |
|
| 1990 |
Winslow JT, Insel TR, Trullas R, Skolnick P. Rat pup isolation calls are reduced by functional antagonists of the NMDA receptor complex. European Journal of Pharmacology. 190: 11-21. PMID 1963846 DOI: 10.1016/0014-2999(90)94107-9 |
0.675 |
|
| 1990 |
Basile AS, Ostrowski NL, Gammal SH, Jones EA, Skolnick P. The involvement of the benzodiazepine receptor in hepatic encephalopathy: evidence for the presence of a benzodiazepine receptor ligand. Advances in Biochemical Psychopharmacology. 46: 189-200. PMID 1963266 |
0.621 |
|
| 1990 |
Sei Y, McIntyre TD, Fride E, Yoshimoto K, Skolnick P, Arora PK. Opiate-induced inhibition of calcium flux in immune cells. Nida Research Monograph. 105: 524-9. PMID 1876108 |
0.774 |
|
| 1989 |
Skolnick P, Marvizón JCG, Jackson BW, Monn JA, Rice KC, Lewin AH. Blockade of N-methyl-D-aspartate induced convulsions by 1-aminocyclopropanecarboxylates Life Sciences. 45: 1647-1655. PMID 2685487 DOI: 10.1016/0024-3205(89)90274-9 |
0.382 |
|
| 1989 |
Trullas R, Jackson B, Skolnick P. Anxiolytic properties of 1-aminocyclopropanecarboxylic acid, a ligand at strychnine-insensitive glycine receptors. Pharmacology, Biochemistry, and Behavior. 34: 313-6. PMID 2576136 DOI: 10.1016/0091-3057(89)90317-1 |
0.685 |
|
| 1989 |
Basile AS, Gammal SH, Jones EA, Skolnick P. GABAA receptor complex in an experimental model of hepatic encephalopathy: evidence for elevated levels of an endogenous benzodiazepine receptor ligand. Journal of Neurochemistry. 53: 1057-63. PMID 2549194 DOI: 10.1111/J.1471-4159.1989.Tb07395.X |
0.65 |
|
| 1989 |
Petitto JM, Skolnick P, Arora PK. Suppression of natural killer cell activity by FG 7142, a benzodiazepine receptor "inverse agonist", Brain Behavior and Immunity. 3: 39-46. PMID 2548642 DOI: 10.1016/0889-1591(89)90004-4 |
0.43 |
|
| 1989 |
Moody EJ, Skolnick P. Chlormethiazole: neurochemical actions at the gamma-aminobutyric acid receptor complex. European Journal of Pharmacology. 164: 153-8. PMID 2546785 DOI: 10.1016/0014-2999(89)90242-2 |
0.443 |
|
| 1989 |
Schwartz RD, Seale TW, Skolnick P, Paul SM. Differential seizure sensitivities to picrotoxinin in two inbred strains of mice (DBA/2J and BALB/c ByJ): parallel changes in GABA receptor-mediated chloride flux and receptor binding Brain Research. 481: 169-174. PMID 2539878 DOI: 10.1016/0006-8993(89)90499-X |
0.34 |
|
| 1989 |
Jones EA, Skolnick P, Gammal SH, Basile AS, Mullen KD. NIH conference. The gamma-aminobutyric acid A (GABAA) receptor complex and hepatic encephalopathy. Some recent advances. Annals of Internal Medicine. 110: 532-46. PMID 2538099 DOI: 10.7326/0003-4819-110-7-532 |
0.631 |
|
| 1989 |
McCabe RT, Schoenheimer JA, Skolnick P, Newman AH, Rice KC, Reig JA, Klein DC. [3H]AHN 086 acylates peripheral benzodiazepine receptors in the rat pineal gland. Febs Letters. 244: 263-7. PMID 2537753 DOI: 10.1016/0014-5793(89)80541-1 |
0.393 |
|
| 1989 |
Basile AS, Bolger GT, Lueddens HW, Skolnick P. Electrophysiological actions of Ro5-4864 on cerebellar Purkinje neurons: evidence for "peripheral" benzodiazepine receptor-mediated depression. The Journal of Pharmacology and Experimental Therapeutics. 248: 463-9. PMID 2536432 |
0.594 |
|
| 1989 |
Trullas R, Jackson B, Skolnick P. Genetic differences in a tail suspension test for evaluating antidepressant activity. Psychopharmacology. 99: 287-8. PMID 2508168 DOI: 10.1007/Bf00442824 |
0.601 |
|
| 1989 |
Bolger GT, Newman AH, Rice KC, Lueddens HW, Basile AS, Skolnick P. Characterization of the effects of AHN 086, an irreversible ligand of "peripheral" benzodiazepine receptors, on contraction in guinea-pig atrial and ileal longitudinal smooth muscle. Canadian Journal of Physiology and Pharmacology. 67: 126-34. PMID 2469529 DOI: 10.1139/Y89-022 |
0.618 |
|
| 1989 |
Marvizón JC, Lewin AH, Skolnick P. 1-Aminocyclopropane carboxylic acid: a potent and selective ligand for the glycine modulatory site of the N-methyl-D-aspartate receptor complex. Journal of Neurochemistry. 52: 992-4. PMID 2465385 DOI: 10.1111/J.1471-4159.1989.Tb02554.X |
0.428 |
|
| 1988 |
Trullas R, Havoundjian H, Skolnick P. Is the benzodiazepine/GABA receptor chloride ionophore complex involved in physical and emotional stress? Advances in Experimental Medicine and Biology. 245: 183-200. PMID 2906519 DOI: 10.1007/978-1-4899-2064-5_14 |
0.612 |
|
| 1988 |
Basile AS, Gammal SH, Mullen KD, Jones EA, Skolnick P. Differential responsiveness of cerebellar Purkinje neurons to GABA and benzodiazepine receptor ligands in an animal model of hepatic encephalopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 2414-21. PMID 2854841 DOI: 10.1523/Jneurosci.08-07-02414.1988 |
0.605 |
|
| 1988 |
Drugan RC, Basile AS, Crawley JN, Paul SM, Skolnick P. Characterization of stress-induced alterations in [3H] Ro5-4864 binding to peripheral benzodiazepine receptors in rat heart and kidney. Pharmacology, Biochemistry, and Behavior. 30: 1015-20. PMID 2852369 DOI: 10.1016/0091-3057(88)90134-7 |
0.606 |
|
| 1988 |
Moody EJ, Skolnick P. The imidazobenzodiazepine Ro 15-4513 antagonizes methoxyflurane anesthesia. Life Sciences. 43: 1269-76. PMID 2845216 DOI: 10.1016/0024-3205(88)90581-4 |
0.382 |
|
| 1988 |
Trullas R, Ginter H, Jackson B, Skolnick P, Allen MS, Hagen TJ, Cook JM. 3-Ethoxy-beta-carboline: a high affinity benzodiazepine receptor ligand with partial inverse agonist properties. Life Sciences. 43: 1189-97. PMID 2845211 DOI: 10.1016/0024-3205(88)90208-1 |
0.67 |
|
| 1988 |
Allen MS, Hagen TJ, Trudell ML, Codding PW, Skolnick P, Cook JM. Synthesis of novel 3-substituted beta-carbolines as benzodiazepine receptor ligands: probing the benzodiazepine receptor pharmacophore. Journal of Medicinal Chemistry. 31: 1854-61. PMID 2842507 DOI: 10.1021/Jm00117A029 |
0.321 |
|
| 1988 |
Bolger GT, Skolnick P, Rice KC, Weissman BA. Differential regulation of mu-opiate receptors in heroin- and morphine-dependent rats. Febs Letters. 234: 22-6. PMID 2839362 DOI: 10.1016/0014-5793(88)81294-8 |
0.58 |
|
| 1988 |
Suzdak PD, Schwartz RD, Skolnick P, Paul SM. Alcohols stimulate gamma-aminobutyric acid receptor-mediated chloride uptake in brain vesicles: correlation with intoxication potency. Brain Research. 444: 340-5. PMID 2834024 DOI: 10.1016/0006-8993(88)90943-2 |
0.354 |
|
| 1988 |
Mantione CR, Goldman ME, Martin B, Bolger GT, Lueddens HW, Paul SM, Skolnick P. Purification and characterization of an endogenous protein modulator of radioligand binding to "peripheral-type" benzodiazepine receptors and dihydropyridine Ca2+-channel antagonist binding sites. Biochemical Pharmacology. 37: 339-47. PMID 2829915 DOI: 10.1016/0006-2952(88)90738-1 |
0.409 |
|
| 1988 |
Basile AS, Lueddens HW, Skolnick P. Regulation of renal peripheral benzodiazepine receptors by anion transport inhibitors. Life Sciences. 42: 715-26. PMID 2828800 DOI: 10.1016/0024-3205(88)90464-X |
0.609 |
|
| 1988 |
Basile AS, Skolnick P. Tissue specific regulation of "peripheral-type" benzodiazepine receptor density after chemical sympathectomy. Life Sciences. 42: 273-83. PMID 2826958 DOI: 10.1016/0024-3205(88)90636-4 |
0.624 |
|
| 1988 |
McIntyre TD, Trullas R, Skolnick P. Asymmetrical activation of GABA-gated chloride channels in cerebral cortex. Pharmacology, Biochemistry, and Behavior. 30: 911-6. PMID 2465553 DOI: 10.1016/0091-3057(88)90119-0 |
0.796 |
|
| 1988 |
Evoniuk G, Skolnick P. Anion regulation of agonist and inverse agonist binding to benzodiazepine receptors. Journal of Neurochemistry. 51: 1169-75. PMID 2458432 DOI: 10.1111/J.1471-4159.1988.Tb03083.X |
0.404 |
|
| 1988 |
Marvizón JC, Skolnick P. [3H]glycine binding is modulated by Mg2+ and other ligands of the NMDA receptor-cation channel complex. European Journal of Pharmacology. 151: 157-8. PMID 2458270 DOI: 10.1016/0014-2999(88)90709-1 |
0.4 |
|
| 1988 |
McIntyre TD, Trullas R, Skolnick P. Differences in the biophysical properties of the benzodiazepine/gamma-aminobutyric acid receptor chloride channel complex in the long-sleep and short-sleep mouse lines. Journal of Neurochemistry. 51: 642-7. PMID 2455777 DOI: 10.1111/J.1471-4159.1988.Tb01086.X |
0.795 |
|
| 1988 |
Marvizón JC, Skolnick P. Enhancement of t-[35S]butylbicyclophosphorothionate and [3H]strychnine binding by monovalent anions reveals similarities between gamma-aminobutyric acid- and glycine-gated chloride channels. Journal of Neurochemistry. 50: 1632-9. PMID 2452238 DOI: 10.1111/J.1471-4159.1988.Tb03053.X |
0.356 |
|
| 1988 |
Bolger GT, Lesieur P, Basile AS, Skolnick P. Modulation of neurotransmitter metabolism by dihydropyridine calcium channel ligands in mouse brain. Brain Research. 438: 101-7. PMID 2449929 DOI: 10.1016/0006-8993(88)91328-5 |
0.579 |
|
| 1988 |
Schwartz RD, Skolnick P, Paul SM. Regulation of γ-aminobutyric acid/barbiturate receptor-gated chloride ion flux in brain vesicles by phospholipase A2: Possible role of oxygen radicals Journal of Neurochemistry. 50: 565-571. PMID 2447244 DOI: 10.1111/J.1471-4159.1988.Tb02948.X |
0.349 |
|
| 1987 |
Janowsky A, Vocci F, Berger P, Angel I, Zelnik N, Kleinman JE, Skolnick P, Paul SM. [3H]GBR-12935 binding to the dopamine transporter is decreased in the caudate nucleus in Parkinson's disease. Journal of Neurochemistry. 49: 617-21. PMID 3598589 DOI: 10.1111/J.1471-4159.1987.Tb02908.X |
0.344 |
|
| 1987 |
Seale TW, Carney JM, Rennert OM, Flux M, Skolnick P. Coincidence of seizure susceptibility to caffeine and to the benzodiazepine inverse agonist, DMCM, in SWR and CBA inbred mice Pharmacology, Biochemistry and Behavior. 26: 381-387. PMID 3575358 DOI: 10.1016/0091-3057(87)90133-X |
0.341 |
|
| 1987 |
Trullas R, Ginter H, Skolnick P. A benzodiazepine receptor inverse agonist inhibits stress-induced ulcer formation. Pharmacology, Biochemistry, and Behavior. 27: 35-9. PMID 3039540 DOI: 10.1016/0091-3057(87)90473-4 |
0.64 |
|
| 1987 |
Das SK, Sikpi MO, Skolnick P. Characterization of [3H]Ro5-4864 binding to "peripheral" benzodiazepine receptors in guinea pig alveolar type II cells. Biochemical Pharmacology. 36: 2221-4. PMID 3038118 DOI: 10.1016/0006-2952(87)90154-7 |
0.374 |
|
| 1987 |
Bolger GT, Basile AS, Janowsky AJ, Paul SM, Skolnick P. Regulation of dihydropyridine calcium antagonist binding sites in the rat hippocampus following neurochemical lesions. Journal of Neuroscience Research. 17: 285-90. PMID 3037095 DOI: 10.1002/Jnr.490170313 |
0.579 |
|
| 1987 |
Basile AS, Skolnick P. Preservation of "peripheral" benzodiazepine receptors: differential effects of freezing on [3H]Ro 5-4864 and [3H]PK 11195 binding. Journal of Pharmacological Methods. 17: 149-56. PMID 3035290 DOI: 10.1016/0160-5402(87)90025-8 |
0.613 |
|
| 1987 |
Arora PK, Hanna EE, Paul SM, Skolnick P. Suppression of the immune response by benzodiazepine receptor inverse agonists. Journal of Neuroimmunology. 15: 1-9. PMID 3033018 DOI: 10.1016/0165-5728(87)90002-6 |
0.419 |
|
| 1987 |
Trullas R, Havoundjian H, Zamir N, Paul S, Skolnick P. Environmentally-induced modification of the benzodiazepine/GABA receptor coupled chloride ionophore. Psychopharmacology. 91: 384-90. PMID 3031719 DOI: 10.1007/Bf00518197 |
0.651 |
|
| 1987 |
Hagen TJ, Skolnick P, Cook JM. Synthesis of 6-substituted beta-carbolines that behave as benzodiazepine receptor antagonists or inverse agonists. Journal of Medicinal Chemistry. 30: 750-3. PMID 3031296 DOI: 10.1021/Jm00387A033 |
0.35 |
|
| 1987 |
Bolger GT, Marcus KA, Daly JW, Skolnick P. Local anesthetics differentiate dihydropyridine calcium antagonist binding sites in rat brain and cardiac membranes. The Journal of Pharmacology and Experimental Therapeutics. 240: 922-30. PMID 3031279 |
0.429 |
|
| 1987 |
Basile AS, Ostrowski NL, Skolnick P. Aldosterone-reversible decrease in the density of renal peripheral benzodiazepine receptors in the rat after adrenalectomy. The Journal of Pharmacology and Experimental Therapeutics. 240: 1006-13. PMID 3031271 |
0.568 |
|
| 1987 |
Drugan RC, Basile AS, Crawley JN, Paul SM, Skolnick P. "Peripheral" benzodiazepine binding sites in the Maudsley reactive rat: selective decrease confined to peripheral tissues. Brain Research Bulletin. 18: 143-5. PMID 3030509 DOI: 10.1016/0361-9230(87)90044-X |
0.54 |
|
| 1987 |
Das SK, Sikpi MO, Skolnick P. Heterogeneity of beta-adrenoreceptors in guinea pig alveolar type II cells. Biochemical and Biophysical Research Communications. 142: 898-903. PMID 3030305 DOI: 10.1016/0006-291X(87)91498-7 |
0.312 |
|
| 1987 |
Trudell ML, Basile AS, Shannon HE, Skolnick P, Cook JM. Synthesis of 7,12-dihydropyrido[3,4-b:5,4-b']diindoles. A novel class of rigid, planar benzodiazepine receptor ligands. Journal of Medicinal Chemistry. 30: 456-8. PMID 3029372 DOI: 10.1021/Jm00386A003 |
0.574 |
|
| 1987 |
Lueddens HWM, Skolnick P. ‘Peripheral-type’ benzodiazepine receptors in the kidney: regulation of radioligand binding by anions and DIDS European Journal of Pharmacology. 133: 205-214. PMID 3028841 DOI: 10.1016/0014-2999(87)90152-X |
0.4 |
|
| 1987 |
Bolger GT, Marcus KA, Thibou R, Skolnick P, Weissman BA. Enhancement of [3H]DAGO1 binding to rat brain by low concentrations of monovalent cations. Canadian Journal of Physiology and Pharmacology. 65: 2338-45. PMID 2835135 DOI: 10.1139/Y87-370 |
0.601 |
|
| 1987 |
Havoundjian H, Trullas R, Paul S, Skolnick P. A physiological role of the benzodiazepine/GABA receptor-chloride ionophore complex in stress. Advances in Experimental Medicine and Biology. 221: 459-75. PMID 2829587 DOI: 10.1007/978-1-4684-7618-7_33 |
0.677 |
|
| 1987 |
Newman AH, Lueddens HWM, Skolnick P, Rice KC. Novel irreversible ligands specific for "peripheral" type benzodiazepine receptors: (±)-, (+)-, and (-)-1-(2-chlorophenyl)-N-(1-methylpropyl)-N-(2-isothiocyanatoethyl)-3- isoquinolinecarboxamide and 1-(2-isothiocyanatoethyl)-7-chloro-1,3-dihydro-5-(4-chlorophenyl)-2H-1,4- benzodiazepin-2-one Journal of Medicinal Chemistry. 30: 1901-1905. PMID 2821259 DOI: 10.1021/Jm00393A036 |
0.379 |
|
| 1987 |
Bassett ML, Mullen KD, Skolnick P, Jones EA. Amelioration of hepatic encephalopathy by pharmacologic antagonism of the GABAA-benzodiazepine receptor complex in a rabbit model of fulminant hepatic failure Gastroenterology. 93: 1069-1077. PMID 2820828 DOI: 10.1016/0016-5085(87)90571-3 |
0.358 |
|
| 1987 |
Basile AS, Weissman BA, Skolnick P. Maximal electroshock increases the density of [3H]Ro 5-4864 binding to mouse cerebral cortex. Brain Research Bulletin. 19: 1-7. PMID 2820550 DOI: 10.1016/0361-9230(87)90158-4 |
0.696 |
|
| 1987 |
Trullas R, Havoundjian H, Skolnick P. Stress-induced changes in t-[35S]butylbicyclophosphorothionate binding to gamma-aminobutyric acid-gated chloride channels are mimicked by in vitro occupation of benzodiazepine receptors. Journal of Neurochemistry. 49: 968-74. PMID 2440992 DOI: 10.1111/J.1471-4159.1987.Tb00988.X |
0.632 |
|
| 1987 |
Schwartz RD, Wess MJ, Labarca R, Skolnick P, Paul SM. Acute stress enhances the activity of the GABA receptor-gated chloride ion channel in brain. Brain Research. 411: 151-5. PMID 2440512 DOI: 10.1016/0006-8993(87)90692-5 |
0.345 |
|
| 1986 |
Bolger GT, Rafferty MF, Crawley JN, Paul SM, Skolnick P. Effects of calcium antagonists on phencyclidine behaviors. Pharmacology, Biochemistry, and Behavior. 25: 45-9. PMID 3749237 DOI: 10.1016/0091-3057(86)90228-5 |
0.33 |
|
| 1986 |
Hauger RL, Hulihan-Giblin B, Skolnick P, Paul SM. Glucostatic regulation of hypothalamic and brainstem [3H](+)-amphetamine binding during food deprivation and refeeding. European Journal of Pharmacology. 124: 267-75. PMID 3732382 DOI: 10.1016/0014-2999(86)90227-X |
0.329 |
|
| 1986 |
Janowsky A, Berger P, Vocci F, Labarca R, Skolnick P, Paul SM. Characterization of sodium-dependent [3H]GBR-12935 binding in brain: a radioligand for selective labelling of the dopamine transport complex. Journal of Neurochemistry. 46: 1272-6. PMID 3081686 DOI: 10.1111/J.1471-4159.1986.Tb00649.X |
0.376 |
|
| 1986 |
Skolnick P, Trullas R, Havoundjian H, Paul S. The benzodiazepine/GABA receptor complex in anxiety. Clinical Neuropharmacology. 9: 43-5. PMID 3032433 |
0.598 |
|
| 1986 |
Havoundjian H, Skolnick P. A quantitative relationship between Cl− enhanced [3H]flunitrazepam and binding to the benzodiazepine/GABA receptor chloride ionophore complex Molecular Brain Research. 1: 281-287. PMID 3030489 DOI: 10.1016/0169-328X(86)90034-3 |
0.425 |
|
| 1986 |
Basile AS, Klein DC, Skolnick P. Characterization of benzodiazepine receptors in the bovine pineal gland: evidence for the presence of an atypical binding site. Brain Research. 387: 127-35. PMID 3024779 DOI: 10.1016/0169-328X(86)90004-5 |
0.641 |
|
| 1986 |
Suzdak PD, Glowa JR, Crawley JN, Schwartz RD, Skolnick P, Paul SM. A selective imidazobenzodiazepine antagonist of ethanol in the rat Science. 234: 1243-1247. PMID 3022383 DOI: 10.1126/Science.3022383 |
0.357 |
|
| 1986 |
Bolger GT, Skolnick P. Novel interactions of cations with dihydropyridine calcium antagonist binding sites in brain. British Journal of Pharmacology. 88: 857-66. PMID 3017494 DOI: 10.1111/J.1476-5381.1986.Tb16259.X |
0.346 |
|
| 1986 |
Drugan RC, Basile AS, Crawley JN, Paul SM, Skolnick P. Inescapable shock reduces [3H]Ro 5-4864 binding to "peripheral-type" benzodiazepine receptors in the rat. Pharmacology, Biochemistry, and Behavior. 24: 1673-7. PMID 3016760 DOI: 10.1016/0091-3057(86)90504-6 |
0.634 |
|
| 1986 |
Havoundjian H, Paul SM, Skolnick P. Rapid, stress-induced modification of the benzodiazepine receptor-coupled chloride ionophore Brain Research. 375: 401-406. PMID 3015336 DOI: 10.1016/0006-8993(86)90767-5 |
0.391 |
|
| 1986 |
Paul SM, Schwartz RD, Creveling CR, Hollingsworth EB, Daly JW, Skolnick P. GABA receptor-mediated chloride transport in a "cell-free" membrane preparation from brain. Science (New York, N.Y.). 233: 228-9. PMID 3014649 DOI: 10.1126/Science.3014649 |
0.485 |
|
| 1986 |
Bolger GT, Weissman BA, Lueddens H, Barrett JE, Witkin J, Paul SM, Skolnick P. Dihydropyridine calcium channel antagonists binding in non-mammalian vertebrates: characterization and relationship to 'peripheral-type' binding sites for benzodiazepines. Brain Research. 368: 351-6. PMID 3008928 DOI: 10.1016/0006-8993(86)90580-9 |
0.571 |
|
| 1986 |
Havoundjian H, Cohen RM, Paul SM, Skolnick P. Differential sensitivity of 'central' and 'peripheral' type benzodiazepine receptors to phospholipase A2 Journal of Neurochemistry. 46: 804-811. PMID 3005493 DOI: 10.1111/j.1471-4159.1986.tb13043.x |
0.302 |
|
| 1986 |
Basile AS, Skolnick P. Subcellular localization of "peripheral-type" binding sites for benzodiazepines in rat brain. Journal of Neurochemistry. 46: 305-8. PMID 2999338 DOI: 10.1111/J.1471-4159.1986.Tb12965.X |
0.622 |
|
| 1986 |
Bolger GT, Rafferty MF, Weissman BA, Rice KC, Skolnick P. Acylating phencyclidines irreversibly enhance brain calcium antagonist binding. Pharmacology, Biochemistry, and Behavior. 25: 51-7. PMID 2944131 DOI: 10.1016/0091-3057(86)90229-7 |
0.609 |
|
| 1986 |
Bolger GT, Rafferty MF, Skolnick P. Enhancement of brain calcium antagonist binding by phencyclidine and related compounds Pharmacology, Biochemistry and Behavior. 24: 417-423. PMID 2939463 DOI: 10.1016/0091-3057(86)90534-4 |
0.404 |
|
| 1986 |
Barrett JE, Witkin JM, Mansbach RS, Skolnick P, Weissman BA. Behavioral studies with anxiolytic drugs. III. Antipunishment actions of buspirone in the pigeon do not involve benzodiazepine receptor mechanisms. The Journal of Pharmacology and Experimental Therapeutics. 238: 1009-13. PMID 2875168 |
0.568 |
|
| 1985 |
Schweri MM, Skolnick P, Rafferty MF, Rice KC, Janowsky AJ, Paul SM. [3H]Threo-(+/-)-methylphenidate binding to 3,4-dihydroxyphenylethylamine uptake sites in corpus striatum: correlation with the stimulant properties of ritalinic acid esters. Journal of Neurochemistry. 45: 1062-70. PMID 4031878 DOI: 10.1111/J.1471-4159.1985.Tb05524.X |
0.361 |
|
| 1985 |
Janowsky A, Schweri MM, Berger P, Long R, Skolnick P, Paul SM. The effects of surgical and chemical lesions on striatal [3H]threo-(+/-)-methylphenidate binding: correlation with [3H]dopamine uptake. European Journal of Pharmacology. 108: 187-91. PMID 3920060 DOI: 10.1016/0014-2999(85)90724-1 |
0.318 |
|
| 1985 |
Weissman BA, Cott J, Weber KH, Skolnick P. Are "peripheral-type" binding sites for benzodiazepines in brain related to the convulsant actions of Ro 5-4864? Progress in Clinical and Biological Research. 192: 197-203. PMID 3001752 |
0.523 |
|
| 1985 |
Mantione CR, Goldman ME, Weissman BA, Paul SM, Skolnick P. Endogenous inhibitors of [3H] Ro 5-4864 binding to "peripheral-type" binding sites for benzodiazepines are present in peripheral tissues and brain. Progress in Clinical and Biological Research. 192: 167-73. PMID 3001748 |
0.546 |
|
| 1985 |
Drugan RC, Maier SF, Skolnick P, Paul SM, Crawley JN. An anxiogenic benzodiazepine receptor ligand induces learned helplessness. European Journal of Pharmacology. 113: 453-7. PMID 2995072 DOI: 10.1016/0014-2999(85)90096-2 |
0.351 |
|
| 1985 |
Skolnick P, Reed GF, Paul SM. Benzodiazepine-receptor mediated inhibition of isolation-induced aggression in mice Pharmacology, Biochemistry and Behavior. 23: 17-20. PMID 2994118 DOI: 10.1016/0091-3057(85)90123-6 |
0.367 |
|
| 1985 |
Angel I, Hauger RL, Luu MD, Giblin B, Skolnick P, Paul SM. Glucostatic regulation of (+)-[3H]amphetamine binding in the hypothalamus: correlation with Na+,K+-ATPase activity. Proceedings of the National Academy of Sciences of the United States of America. 82: 6320-4. PMID 2994071 DOI: 10.1073/Pnas.82.18.6320 |
0.318 |
|
| 1985 |
Bolger GT, Weissman BA, Lueddens H, Basile AS, Mantione CR, Barrett JE, Witkin JM, Paul SM, Skolnick P. Late evolutionary appearance of 'peripheral-type' binding sites for benzodiazepines. Brain Research. 338: 366-70. PMID 2992689 DOI: 10.1016/0006-8993(85)90170-2 |
0.684 |
|
| 1985 |
Basile AS, Paul SM, Skolnick P. Adrenalectomy reduces the density of 'peripheral-type' binding sites for benzodiazepines in the rat kidney. European Journal of Pharmacology. 110: 149-50. PMID 2988979 DOI: 10.1016/0014-2999(85)90044-5 |
0.573 |
|
| 1985 |
Schwartz RD, Thomas JW, Kempner ES, Skolnick P, Paul SM. Radiation inactivation studies of the benzodiazepine/gamma-aminobutyric acid/chloride ionophore receptor complex. Journal of Neurochemistry. 45: 108-15. PMID 2987406 DOI: 10.1111/J.1471-4159.1985.Tb05481.X |
0.359 |
|
| 1985 |
Weber KH, Kuhn FJ, Böke-Kuhn K, Lehr E, Danneberg PB, Hommer D, Paul SM, Skolnick P. Pharmacological and neurochemical properties of 1,4-diazepines with two annelated heterocycles ('hetrazepines'). European Journal of Pharmacology. 109: 19-31. PMID 2986988 DOI: 10.1016/0014-2999(85)90535-7 |
0.407 |
|
| 1985 |
Mendelson WB, Martin JV, Wagner R, Roseberry C, Skolnick P, Weissman BA, Squires R. Are the toxicities of pentobarbital and ethanol mediated by the GABA-benzodiazepine receptor-chloride ionophore complex? European Journal of Pharmacology. 108: 63-70. PMID 2984019 DOI: 10.1016/0014-2999(85)90283-3 |
0.586 |
|
| 1985 |
Skolnick P, Weissman BA, Youdim MB. Monoaminergic involvement in the pharmacological actions of buspirone. British Journal of Pharmacology. 86: 637-44. PMID 2933109 DOI: 10.1111/J.1476-5381.1985.Tb08940.X |
0.568 |
|
| 1985 |
Bolger GT, Rafferty MF, Skolnick P. Phencyclidine increases the affinity of dihydropyridine calcium channel antagonist binding in rat brain. Naunyn-Schmiedebergs Archives of Pharmacology. 330: 227-234. PMID 2932650 DOI: 10.1007/Bf00572438 |
0.378 |
|
| 1985 |
Bolger GT, Weissman BA, Skolnick P. The behavioral effects of the calcium agonist Bay K 8644 in the mouse: antagonism by the calcium antagonist nifedipine. Naunyn-Schmiedeberg's Archives of Pharmacology. 328: 373-7. PMID 2581145 DOI: 10.1007/Bf00692903 |
0.571 |
|
| 1985 |
Weissman BA, Cott J, Jackson JA, Bolger GT, Weber KH, Horst WD, Paul SM, Skolnick P. "Peripheral-type" binding sites for benzodiazepines in brain: relationship to the convulsant actions of Ro 5-4864. Journal of Neurochemistry. 44: 1494-9. PMID 2580949 DOI: 10.1111/J.1471-4159.1985.Tb08787.X |
0.544 |
|
| 1985 |
Schwartz R, Jackson J, Weigert D, Skolnick P, Paul S. Characterization of barbiturate-stimulated chloride efflux from rat brain synaptoneurosomes The Journal of Neuroscience. 5: 2963-2970. DOI: 10.1523/Jneurosci.05-11-02963.1985 |
0.352 |
|
| 1985 |
Crawley J, Ninan P, Pickar D, Chrousos G, Linnoila M, Skolnick P, Paul S. Neuropharmacological antagonism of the beta-carboline-induced "anxiety" response in rhesus monkeys The Journal of Neuroscience. 5: 477-485. DOI: 10.1523/Jneurosci.05-02-00477.1985 |
0.301 |
|
| 1984 |
Hauger RL, Hulihan-Giblin B, Skolnick P, Paul SM. Characteristics of [3H](+)-amphetamine binding sites in the rat central nervous system. Life Sciences. 34: 771-82. PMID 6700378 DOI: 10.1016/0024-3205(84)90385-0 |
0.359 |
|
| 1984 |
Skolnick P, Crawley JN, Glowa JR, Paul SM. β-Carboline-induced anxiety states Psychopathology. 17: 52-60. PMID 6505120 DOI: 10.1159/000284131 |
0.325 |
|
| 1984 |
Weissman BA, Burke TR, Rice KC, Skolnick P. Alkyl-substituted gamma-butyrolactones inhibit [35S]TBPS binding to a GABA linked chloride ionophore. European Journal of Pharmacology. 105: 195-6. PMID 6489449 DOI: 10.1016/0014-2999(84)90669-1 |
0.504 |
|
| 1984 |
Schwartz RD, Skolnick P, Hollingsworth EB, Paul SM. Barbiturate and picrotoxin-sensitive chloride efflux in rat cerebral cortical synaptoneurosomes. Febs Letters. 175: 193-6. PMID 6479335 DOI: 10.1016/0014-5793(84)80597-9 |
0.307 |
|
| 1984 |
Insel TR, Ninan PT, Aloi J, Jimerson DC, Skolnick P, Paul SM. A benzodiazepine receptor-mediated model of anxiety. Studies in nonhuman primates and clinical implications. Archives of General Psychiatry. 41: 741-50. PMID 6331336 DOI: 10.1001/Archpsyc.1984.01790190015002 |
0.34 |
|
| 1984 |
Guzman F, Cain M, Larscheid P, Hagen T, Cook JM, Schweri M, Skolnick P, Paul SM. Biomimetic approach to potential benzodiazepine receptor agonists and antagonists. Journal of Medicinal Chemistry. 27: 564-70. PMID 6325688 DOI: 10.1002/Chin.198443191 |
0.386 |
|
| 1984 |
Weissman BA, Cott J, Hommer D, Paul S, Skolnick P. Electrophysiological and pharmacological actions of the convulsant benzodiazepine Ro 5-4864. European Journal of Pharmacology. 97: 257-63. PMID 6323193 DOI: 10.1016/0014-2999(84)90457-6 |
0.623 |
|
| 1984 |
Weissman BA, Bolger GT, Isaac L, Paul SM, Skolnick P. Characterization of the binding of [3H]Ro 5-4864, a convulsant benzodiazepine, to guinea pig brain. Journal of Neurochemistry. 42: 969-75. PMID 6321666 DOI: 10.1111/J.1471-4159.1984.Tb12698.X |
0.582 |
|
| 1984 |
Skolnick P, Paul SM, Weissman BA. Preclinical pharmacology of buspirone hydrochloride. Pharmacotherapy. 4: 308-14. PMID 6151169 DOI: 10.1002/J.1875-9114.1984.Tb03384.X |
0.568 |
|
| 1984 |
Skolnick P, Ninan P, Insel T, Crawley J, Paul S. A novel chemically induced animal model of human anxiety. Psychopathology. 25-36. PMID 6143342 DOI: 10.1159/000284074 |
0.342 |
|
| 1984 |
Weissman BA, Skolnick P, Klein DC. Regulation of "peripheral-type" binding sites for benzodiazepines in the pineal gland. Pharmacology, Biochemistry, and Behavior. 21: 821-4. PMID 6097917 DOI: 10.1016/S0091-3057(84)80059-3 |
0.576 |
|
| 1984 |
Mantione CR, Weissman BA, Goldman ME, Paul SM, Skolnick P. Endogenous inhibitors of 4'-[3H]chlorodiazepam (Ro 5-4864) binding to 'peripheral' sites for benzodiazepines. Febs Letters. 176: 69-74. PMID 6092140 DOI: 10.1016/0014-5793(84)80913-8 |
0.594 |
|
| 1984 |
Bolger GT, Mezey E, Cott J, Weissman BA, Paul SM, Skolnick P. Differential regulation of 'central' and 'peripheral' benzodiazepine binding sites in the rat olfactory bulb. European Journal of Pharmacology. 105: 143-8. PMID 6092112 DOI: 10.1016/0014-2999(84)90658-7 |
0.574 |
|
| 1984 |
Squires RF, Saederup E, Crawley JN, Skolnick P, Paul SM. Convulsant potencies of tetrazoles are highly correlated with actions on GABA/benzodiazepine/picrotoxin receptor complexes in brain. Life Sciences. 35: 1439-44. PMID 6090836 DOI: 10.1016/0024-3205(84)90159-0 |
0.404 |
|
| 1983 |
Weissman BA, Cott J, Paul SM, Skolnick P. Ro 5-4864: a potent benzodiazepine convulsant. European Journal of Pharmacology. 90: 149-50. PMID 6873175 DOI: 10.1016/0014-2999(83)90229-7 |
0.503 |
|
| 1983 |
Rehavi M, Skolnick P, Paul SM. Subcellular distribution of high affinity [3H]imipramine binding and [3H]serotonin uptake in rat brain European Journal of Pharmacology. 87: 335-339. PMID 6840193 DOI: 10.1016/0014-2999(83)90349-7 |
0.347 |
|
| 1983 |
Rehavi M, Tracer H, Rice K, Skolnick P, Paul SM. [3H]2-nitroimipramine: A selective "slowly-dissociating" probe of the imipramine binding site ("serotonin transporter") in platelets and brain Life Sciences. 32: 645-653. PMID 6835029 DOI: 10.1016/0024-3205(83)90210-2 |
0.341 |
|
| 1983 |
Skolnick P, Paul S, Crawley J, Lewin E, Lippa A, Clody D, Irmscher K, Saiko O, Minck KO. Antagonism of the anxiolytic action of diazepam and chlordiazepoxide by the novel imidazopyridines, EMD 39593 and EMD 41717. European Journal of Pharmacology. 88: 319-27. PMID 6688050 DOI: 10.1016/0014-2999(83)90582-4 |
0.354 |
|
| 1983 |
Weissman BA, Cott J, Hommer D, Quirion R, Paul S, Skolnick P. Pharmacological, electrophysiological, and neurochemical actions of the convulsant benzodiazepine Ro 5-4864 (4'-chlordiazepam). Advances in Biochemical Psychopharmacology. 38: 139-51. PMID 6670623 |
0.504 |
|
| 1983 |
Schweri MM, Paul SM, Skolnick P. Strain differences in susceptibility to the convulsant actions of 3-carbomethoxy-β-carboline Pharmacology, Biochemistry and Behavior. 19: 951-955. PMID 6657728 DOI: 10.1016/0091-3057(83)90397-0 |
0.329 |
|
| 1983 |
Mendelson WB, Davis T, Paul SM, Skolnick P. Do benzodiazepine receptors mediate the anticonflict action of pentobarbital? Life Sciences. 32: 2241-6. PMID 6302426 DOI: 10.1016/0024-3205(83)90422-8 |
0.381 |
|
| 1983 |
Mendelson WB, Cain M, Cook JM, Paul SM, Skolnick P. A benzodiazepine receptor antagonist decreases sleep and reverses the hypnotic actions of flurazepam. Science (New York, N.Y.). 219: 414-6. PMID 6294835 DOI: 10.1126/Science.6294835 |
0.312 |
|
| 1983 |
Ninan PT, Insel TM, Cohen RM, Cook JM, Skolnick P, Paul SM. Benzodiazepine receptor-mediated experimental "anxiety" in primates. Science (New York, N.Y.). 218: 1332-4. PMID 6293059 DOI: 10.1126/Science.6293059 |
0.406 |
|
| 1983 |
CAIN M, WEBER RW, GUZMAN F, COOK JM, BARKER SA, RICE KC, CRAWLEY JN, PAUL SM, SKOLNICK P. ChemInform Abstract: β-CARBOLINES: SYNTHESIS AND NEUROCHEMICAL AND PHARMACOLOGICAL ACTIONS ON BRAIN BENZODIAZEPINE RECEPTORS Chemischer Informationsdienst. 14. DOI: 10.1002/Chin.198305238 |
0.321 |
|
| 1982 |
Hauger RL, Skolnick P, Paul SM. Specific [3H]β-phenylethylamine binding sites in rat brain European Journal of Pharmacology. 83: 147-148. PMID 7128696 DOI: 10.1016/0014-2999(82)90301-6 |
0.302 |
|
| 1982 |
Paul SM, Hulihan-Giblin B, Skolnick P. (+)-Amphetamine binding to rat hypothalamus: Relation to anorexic potency of phenylethylamines Science. 218: 487-490. PMID 7123250 DOI: 10.1126/Science.7123250 |
0.39 |
|
| 1982 |
Rehavi M, Ittah Y, Skolnick P, Rice KC, Paul SM. Nitroimipramines - Synthesis and pharmacological effects of potent long-acting inhibitors of [3H] serotonin uptake and [3H] imipramine binding Naunyn-Schmiedeberg's Archives of Pharmacology. 320: 45-49. PMID 7121610 DOI: 10.1007/Bf00499070 |
0.345 |
|
| 1982 |
Paul SM, Hulihan B, Hauger R, Skolnick P. High affinity and stereospecific binding of [3H]d-amphetamine to rat brain European Journal of Pharmacology. 78: 145-147. PMID 7075663 DOI: 10.1016/0014-2999(82)90386-7 |
0.324 |
|
| 1982 |
Rehavi M, Skolnick P, Paul SM. Solubilization and partial purification of the high affinity [3H] imipramine binding site from human platelets Febs Letters. 150: 514-518. PMID 6297983 DOI: 10.1016/0014-5793(82)80802-8 |
0.342 |
|
| 1982 |
Skolnick P, Schweri M, Kutter E, Williams E, Paul S. Inhibition of [3H]diazepam and [3H]3-carboethoxy-beta-carboline binding by irazepine: evidence for multiple "domains" of the benzodiazepine receptor. Journal of Neurochemistry. 39: 1142-6. PMID 6288861 DOI: 10.1111/J.1471-4159.1982.Tb11507.X |
0.372 |
|
| 1982 |
Rehavi M, Skolnick P, Paul SM. Effects of tetrazole derivatives on [3H]diazepam binding in vitro: Correlation with convulsant potency European Journal of Pharmacology. 78: 353-356. PMID 6279412 DOI: 10.1016/0014-2999(82)90037-1 |
0.426 |
|
| 1982 |
Skolnick P, Rice KC, Barker JL, Paul SM. Interaction of barbiturates with benzodiazepine receptors in the central nervous system. Brain Research. 233: 143-56. PMID 6277423 DOI: 10.1016/0006-8993(82)90936-2 |
0.448 |
|
| 1982 |
Paul SM, Skolnick P. Comparative neuropharmacology of antianxiety drugs Pharmacology, Biochemistry and Behavior. 17: 37-41. PMID 6135226 DOI: 10.1016/0091-3057(82)90508-1 |
0.41 |
|
| 1982 |
Skolnick P, Schweri MM, Williams EF, Moncada VY, Paul SM. An in vitro binding assay which differentiates benzodiazepine 'agonists' and 'antagonists'. European Journal of Pharmacology. 78: 133-6. PMID 6122583 DOI: 10.1016/0014-2999(82)90383-1 |
0.406 |
|
| 1982 |
M. Cook J, Cain M, Guzman F, C. Rice K, Skolnick P. Biomimetic Approach to Potential Benzodiazepine Agonists and Antagonists Heterocycles. 19: 1003. DOI: 10.3987/R-1982-06-1003 |
0.331 |
|
| 1981 |
Paul SM, Rehavi M, Skolnick P, Ballenger JC, Goodwin FK. Depressed patients have decreased binding of tritiated imipramine to platelet serotonin "transporter". Archives of General Psychiatry. 38: 1315-7. PMID 7316676 DOI: 10.1001/Archpsyc.1981.01780370017001 |
0.318 |
|
| 1981 |
Paul SM, Rehavi M, Rice KC, Ittah Y, Skolnick P. Does high affinity [3H] imipramine binding label serotonin reuptake sites in brain and platelet? Life Sciences. 28: 2753-2760. PMID 7266248 DOI: 10.1016/0024-3205(81)90177-6 |
0.359 |
|
| 1981 |
Rehavi M, Ittah Y, Rice KC, Skolnick P, Goodwin FK, Paul SM. 2-nitroimipramine: a selective irreversible inhibitor of [3H] serotonin uptake and [3H] imipramine binding in platelets. Biochemical and Biophysical Research Communications. 99: 954-9. PMID 7247951 DOI: 10.1016/0006-291X(81)91255-9 |
0.342 |
|
| 1981 |
Rehavi M, Skolnick P, Hulihan B, Paul SM. 'High affinity' binding of [3H] desipramine to rat cerebral cortex: Relationship to tricyclic antidepressant-induced inhibition of norepinephrine uptake European Journal of Pharmacology. 70: 597-599. PMID 7238579 DOI: 10.1016/0014-2999(81)90376-9 |
0.361 |
|
| 1981 |
Williams EF, Rice KC, Mattson M, Paul SM, Skolnick P. In vivo effects of two novel alkylating benzodiazepines, irazepine and kenazepine. Pharmacology, Biochemistry, and Behavior. 14: 487-91. PMID 7232472 DOI: 10.1016/0091-3057(81)90307-5 |
0.389 |
|
| 1981 |
Quirion R, Rice KC, Skolnick P, Paul S, Pert CB. Stereospecific displacement of [3H]phencyclidine (PCP) receptor binding by an enantiomeric pair of PCP analogs. European Journal of Pharmacology. 74: 107-8. PMID 6459238 DOI: 10.1016/0014-2999(81)90330-7 |
0.41 |
|
| 1981 |
Williams EF, Paul SM, Rice KC, Cain M, Skolnick P. Binding of [3H]ethyl-beta-carboline-3-carboxylate to brain benzodiazepine receptors: effect of drugs and anions. Febs Letters. 132: 269-72. PMID 6271593 DOI: 10.1016/0014-5793(81)81176-3 |
0.434 |
|
| 1981 |
Nimit Y, Skolnick P, Daly JW. Adenosine and cyclic AMP in rat cerebral cortical slices: effects of adenosine uptake inhibitors and adenosine deaminase inhibitors. Journal of Neurochemistry. 36: 908-12. PMID 6259294 DOI: 10.1111/J.1471-4159.1981.Tb01680.X |
0.489 |
|
| 1981 |
Skolnick P, Moncada V, Barker JL, Paul SM. Pentobarbital: dual actions to increase brain benzodiazepine receptor affinity. Science (New York, N.Y.). 211: 1448-50. PMID 6258230 DOI: 10.1126/Science.6258230 |
0.462 |
|
| 1981 |
Skolnick P, Lock KL, Paul SM, Marangos PJ, Jones R, Irmscher K. Increased benzodiazepine receptor number elicited in vitro by a novel purine, EMD 28422. European Journal of Pharmacology. 67: 179-86. PMID 6257526 DOI: 10.1016/0014-2999(80)90496-3 |
0.453 |
|
| 1981 |
Crawley JN, Marangos PJ, Paul SM, Skolnick P, Goodwin FK. Interaction between purine and benzodiazepine: Inosine reverses diazepam-induced stimulation of mouse exploratory behavior. Science (New York, N.Y.). 211: 725-7. PMID 6256859 DOI: 10.1126/Science.6256859 |
0.325 |
|
| 1980 |
Rehavi M, Paul SM, Skolnick P, Goodwin FK. Demonstration of specific high affinity binding sites for [3H] imipramine in human brain. Life Sciences. 26: 2273-9. PMID 7401921 DOI: 10.1016/0024-3205(80)90213-1 |
0.385 |
|
| 1980 |
Huang A, Barker JL, Paul SM, Moncada V, Skolnick P. Characterization of benzodiazepine receptors in primary cultures of fetal mouse brain and spinal cord neurons. Brain Research. 190: 485-91. PMID 7370801 DOI: 10.1016/0006-8993(80)90290-5 |
0.313 |
|
| 1980 |
Paul SM, Zatz M, Skolnick P. Demonstration of brain-specific benzodiazepine receptors in rat retina Brain Research. 187: 243-246. PMID 7357471 DOI: 10.1016/0006-8993(80)90513-2 |
0.345 |
|
| 1980 |
Williams EF, Rice KC, Paul SM, Skolnick P. Heterogeneity of benzodiazepine receptors in the central nervous system demonstrated with kenazepine, an alkylating benzodiazepine. Journal of Neurochemistry. 35: 591-7. PMID 6256492 DOI: 10.1111/J.1471-4159.1980.Tb03695.X |
0.422 |
|
| 1980 |
Paul SM, Skolnick P, Zatz M. Avermectin B(1a): An irreversible activator of the γ-aminobutyric acid-benzodiazepine-chloride-ionophore receptor complex Biochemical and Biophysical Research Communications. 96: 632-638. PMID 6252889 DOI: 10.1016/0006-291X(80)91402-3 |
0.437 |
|
| 1980 |
Brossi A, Rice KC, Mak CP, Reden J, Jacobson AE, Nimitkitpaisan Y, Skolnick P, Daly J. Mammalian alkaloids. 8. Synthesis and biological effects of tetrahydropapaveroline related 1-benzyltetrahydroisoquinolines. Journal of Medicinal Chemistry. 23: 648-52. PMID 6248642 DOI: 10.1002/Chin.198043308 |
0.402 |
|
| 1980 |
Tallman JF, Paul SM, Skolnick P, Gallager DW. Receptors for the age of anxiety: pharmacology of the benzodiazepines. Science (New York, N.Y.). 207: 274-81. PMID 6101294 DOI: 10.1126/Science.6101294 |
0.427 |
|
| 1980 |
Paul SM, Syapin PJ, Paugh BA, Moncada V, Skolnick P. Correlation between benzodiazepine receptor occupation and anticonvulsant effects of diazepam. Nature. 281: 688-9. PMID 233132 DOI: 10.1038/281688A0 |
0.414 |
|
| 1980 |
Marangos PJ, Clark R, Martino AM, Paul SM, Skolnick P. Demonstration of two new endogenous "benzodiazepine-like" compounds from brain. Psychiatry Research. 1: 121-30. PMID 45129 DOI: 10.1016/0165-1781(79)90052-0 |
0.334 |
|
| 1979 |
Skolnick P, Paul SM, Marangos PJ. Brain benzodiazepine levels following intravenous administration of [3H]diazepam: relationship to the potentiation of purinergic depression of central nervous system neurons Canadian Journal of Physiology and Pharmacology. 57: 1040-1042. PMID 519536 DOI: 10.1139/Y79-157 |
0.385 |
|
| 1979 |
Rice KC, Brossi A, Tallman J, Paul SM, Skolnick P. Irazepine, and noncompetitive, irreversible inhibitor of 3H-diazepam binding to benzodiazepine receptors. Nature. 278: 854-5. PMID 440412 DOI: 10.1038/278854A0 |
0.419 |
|
| 1979 |
Syapin PJ, Skolnick P. Characterization of benzodiazepine binding sites in cultured cells of neural origin. Journal of Neurochemistry. 32: 1047-51. PMID 430037 DOI: 10.1111/J.1471-4159.1979.Tb04592.X |
0.353 |
|
| 1979 |
Marangos PJ, Paul SM, Goodwin FK, Skolnick P. Putative endogenous ligands for the benzodiazepine receptor. Life Sciences. 25: 1093-102. PMID 390284 DOI: 10.1016/0024-3205(79)90130-9 |
0.345 |
|
| 1979 |
Skolnick P, Syapin PJ, Paugh BA, Moncada V, Marangos PJ, Paul SM. Inosine, an endogenous ligand of the brain benzodiazepine receptor, antagonizes pentylenetetrazole-evoked seizures. Proceedings of the National Academy of Sciences of the United States of America. 76: 1515-8. PMID 286337 DOI: 10.1073/Pnas.76.3.1515 |
0.39 |
|
| 1979 |
Skolnick P, Syapin PJ, Paugh BA, Paul SM. Reduction in benzodiazepine receptors associated with Purkinje cell degeneration in ‘nervous’ mutant mice Nature. 277: 397-399. PMID 233119 DOI: 10.1038/277397A0 |
0.429 |
|
| 1979 |
Skolnick P, Marangos PJ, Syapin P, Goodwin FK, Paul SM. CNS benzodiazepine receptors: physiological studies and putative endogenous ligands. Pharmacology, Biochemistry, and Behavior. 10: 815-23. PMID 40256 DOI: 10.1016/0091-3057(79)90340-X |
0.413 |
|
| 1979 |
MacDonald JF, Barker JL, Paul SM, Marangos PJ, Skolnick P. Inosine may be an endogenous ligand for benzodiazepine receptors on cultured spinal neurons. Science (New York, N.Y.). 205: 715-7. PMID 37602 DOI: 10.1126/Science.37602 |
0.323 |
|
| 1979 |
RICE KC, BROSSI A, TALLMAN J, PAUL SM, SKOLNICK P. ChemInform Abstract: IRAZEPINE, A NONCOMPETITIVE, IRREVERSIBLE INHIBITOR OF 3H-DIAZEPAM BINDING TO BENZODIAZEPINE RECEPTORS Chemischer Informationsdienst. 10. DOI: 10.1002/Chin.197930382 |
0.416 |
|
| 1978 |
Williamson MJ, Paul SM, Skolnick P. Labelling of benzodiazepine receptors in vivo. Nature. 275: 551-3. PMID 692734 DOI: 10.1038/275551A0 |
0.441 |
|
| 1978 |
Skolnick P, Nimitkitpaisan Y, Stalvey L, Daly JW. Inhibition of brain adenosine deaminase by 2'-deoxycoformycin and erythro-9-(2-hydroxy-3-nonyl) adenine. Journal of Neurochemistry. 30: 1479-82. PMID 670988 DOI: 10.1111/J.1471-4159.1978.Tb10496.X |
0.429 |
|
| 1978 |
Skolnick P, Daly JW, Segal DS. Neurochemical and behavioral effects of clonidine and related imidazolines: interaction with alpha-adrenoceptors. European Journal of Pharmacology. 47: 451-5. PMID 204500 DOI: 10.1016/0014-2999(78)90126-7 |
0.469 |
|
| 1978 |
Davis JN, Arnett CD, Hoyler E, Stalvey LP, Daly JW, Skolnick P. Brain alpha-adrenergic receptors: comparison of [3H]WB 4101 binding with norepinephrine-stimulated cyclic AMP accumulation in rat cerebral cortex. Brain Research. 159: 125-35. PMID 31963 DOI: 10.1016/0006-8993(78)90114-2 |
0.531 |
|
| 1978 |
Williamson MJ, Paul SM, Skolnick P. Demonstration of [3H] diazepam binding to benzodiazepine receptors in vivo. Life Sciences. 23: 1935-40. PMID 31535 DOI: 10.1016/0024-3205(78)90560-X |
0.307 |
|
| 1978 |
Nimitkitpaisan Y, Skolnick P. Catecholamine receptors and cyclic and formation in the central nervous system: Effects of tetrahydroisoquinoline derivatives Life Sciences. 23: 375-382. PMID 29182 DOI: 10.1016/0024-3205(78)90023-1 |
0.424 |
|
| 1978 |
Skolnick P, Stalvey LP, Daly JW, Hoyler E, Davis JN. Binding of alpha-and beta-adrenergic ligands to cerebral cortical membranes: effect of 6-hydroxydopamine treatment and relationship to the responsiveness of cyclic amp-generating systems in two rat strains. European Journal of Pharmacology. 47: 201-10. PMID 23299 DOI: 10.1016/0014-2999(78)90391-6 |
0.494 |
|
| 1977 |
Paul SM, Skolnick P. Catechol oestrogens inhibit oestrogen elicited accumulation of hypothalamic cyclic AMP suggesting role as endogenous anti-oestrogens [34] Nature. 266: 559-561. PMID 193036 DOI: 10.1038/266559A0 |
0.306 |
|
| 1977 |
Skolnick P, Daly JW. Strain differences in responsiveness of norepinephrine-sensitive adenosine 3',5'-monophosphate-generating systems in rat brain slices after intraventricular administration of 6-hydroxydopamine. European Journal of Pharmacology. 41: 145-52. PMID 188662 DOI: 10.1016/0014-2999(77)90203-5 |
0.453 |
|
| 1977 |
Skolnick P, Stalvey LP, Daly JW. Blockade of central beta-adrenergic receptors by tazolol (1-isopropylamino-3-(2-thiazoloxy)-2-propanol). Life Sciences. 21: 1655-63. PMID 23478 DOI: 10.1016/0024-3205(77)90245-4 |
0.498 |
|
| 1976 |
Skolnick P, Daly JW. Interaction of clonidine with pre- and post-synaptic adrenergic receptors of rat brain: effects on cyclic AMP-generating systems. European Journal of Pharmacology. 39: 11-21. PMID 183964 DOI: 10.1016/0014-2999(76)90108-4 |
0.482 |
|
| 1976 |
Skolnick P, Daly JW. Antagonism of alpha- and beta-adrenergic-mediated accumulations of cyclic AMP in rat cerebral cortical slices by the beta-antagonist (-)alprenolol. Life Sciences. 19: 497-503. PMID 8683 DOI: 10.1016/0024-3205(76)90228-9 |
0.507 |
|
| 1976 |
Skolnick P, Daly JW, Freedman R, Hoffer BJ. Interrelationship between catecholamine-stimulated formation of adenosine 3',5'-monophosphate in cerebellar slices and inhibitory effects on cerebellar Purkinje cells: antagonism by neuroleptic compounds. The Journal of Pharmacology and Experimental Therapeutics. 197: 280-92. PMID 5595 |
0.367 |
|
| 1975 |
Skolnick P, Daly JW. Stimulation of adenosine 3',5'-monophosphate formation by alpha and beta adrenergic agonists in rat cerebral cortical slices: effects of clonidine. Molecular Pharmacology. 11: 545-51. PMID 241008 |
0.378 |
|
| 1975 |
Skolnick P, Daly JW. Stimulation of adenosine 3',5'-monophosphate formation in rat cerebral cortical slices by methoxamine: interaction with an alpha adrenergic receptor. The Journal of Pharmacology and Experimental Therapeutics. 193: 549-58. PMID 238025 |
0.43 |
|
| 1975 |
Weissman BA, Skolnick P. Stimulation of Adenosine 3',5'-monophosphate formation in incubated rat hypothalamus by estrogenic compounds: relationship to biologic potency and blockade by anti-estrogens. Neuroendocrinology. 18: 27-34. PMID 233937 |
0.508 |
|
| 1975 |
Weissman BA, Daly JW, Skolnick P. Diethylstilbestrol-elicited accumulation of cyclic AMP in incubated rat hypothalamus. Endocrinology. 97: 1559-66. PMID 173528 DOI: 10.1210/Endo-97-6-1559 |
0.652 |
|
| 1975 |
Skolnick P, Schultz J, Daly JW. Repetitive stimulation of cyclic adenosine 3',5'-monophosphate formation by adrenergic agonists in incubated slices from rat cerebral cortex. Journal of Neurochemistry. 24: 1263-5. PMID 165265 DOI: 10.1111/J.1471-4159.1975.Tb03909.X |
0.392 |
|
| 1975 |
Skolnick P, Daly JW. Functional compartments of adenine nucleotides serving as precursors of adenosine 3',5'-monophosphate in mouse cerebral cortex. Journal of Neurochemistry. 24: 451-6. PMID 163293 DOI: 10.1111/J.1471-4159.1975.Tb07661.X |
0.47 |
|
| 1974 |
Skolnick P, Daly JW. The accumulation of adenosine 3',5'-monophosphate in cerebral cortical slices of the quaking mouse, a neurologic mutant. Brain Research. 73: 513-25. PMID 4366158 DOI: 10.1016/0006-8993(74)90674-X |
0.469 |
|
| 1974 |
Skolnick P, Daly JW. Norepinephrine-sensitive adenylate cyclases in rat brain: relation to behavior and tyrosine hydroxylase. Science (New York, N.Y.). 184: 175-7. PMID 4150105 DOI: 10.1126/Science.184.4133.175 |
0.436 |
|
| 1973 |
Skolnick P, Huang M, Daly J, Hoffer B. Accumulation of adenosine 3', 5'-monophosphate in incubated slices from discrete regions of squirrel monkey cerebral cortex: effect of norepinephrine, serotonin and adenosine. Journal of Neurochemistry. 21: 237-40. PMID 4352758 DOI: 10.1111/J.1471-4159.1973.Tb04243.X |
0.464 |
|
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