| Year |
Citation |
Score |
| 2023 |
Forde S, Vozza G, Brayden DJ, Byrne HJ, Frías JM, Ryan SM. Evaluation of Selenomethionine Entrapped in Nanoparticles for Oral Supplementation Using In Vitro, Ex Vivo and In Vivo Models. Molecules (Basel, Switzerland). 28. PMID 37049704 DOI: 10.3390/molecules28072941 |
0.304 |
|
| 2022 |
Khalid Danish M, Gleeson JP, Brayden DJ, Byrne HJ, Frías JM, Ryan SM. Formulation, Characterisation and Evaluation of the Antihypertensive Peptides, Isoleucine-Proline-Proline and Leucine-Lysine-Proline in Chitosan Nanoparticles Coated with Zein for Oral Drug Delivery. International Journal of Molecular Sciences. 23. PMID 36232463 DOI: 10.3390/ijms231911160 |
0.632 |
|
| 2022 |
Lundquist P, Khodus G, Niu Z, Thwala LN, McCartney F, Simoff I, Andersson E, Beloqui A, Mabondzo A, Robla S, Webb DL, Hellström PM, Keita ÅV, Sima E, Csaba N, ... ... Brayden DJ, et al. Barriers to the Intestinal Absorption of Four Insulin-Loaded Arginine-Rich Nanoparticles in Human and Rat. Acs Nano. PMID 35998570 DOI: 10.1021/acsnano.2c04330 |
0.777 |
|
| 2021 |
Shrestha N, Xu Y, Prévost JRC, McCartney F, Brayden D, Frédérick R, Beloqui A, Préat V. Impact of PEGylation on antibody-loaded nanoparticulate drug delivery system on treatment of inflammatory bowel disease. Acta Biomaterialia. PMID 34923097 DOI: 10.1016/j.actbio.2021.12.015 |
0.761 |
|
| 2021 |
Maher S, Brayden DJ. Formulation strategies to improve the efficacy of intestinal permeation enhancers. Advanced Drug Delivery Reviews. 177: 113925. PMID 34418495 DOI: 10.1016/j.addr.2021.113925 |
0.365 |
|
| 2021 |
Heade J, McCartney F, Chenlo M, Marro OM, Severic M, Kent R, Bleiel SB, Alvarez CV, Griffin BT, Brayden DJ. Synthesis and In Vivo Evaluation of Insulin-Loaded Whey Beads as an Oral Peptide Delivery System. Pharmaceutics. 13. PMID 34064415 DOI: 10.3390/pharmaceutics13050656 |
0.75 |
|
| 2021 |
McCartney F, Perinelli DR, Tiboni M, Cavanagh R, Lucarini S, Filippo Palmieri G, Casettari L, Brayden DJ. Permeability-enhancing effects of three laurate-disaccharide monoesters across isolated rat intestinal mucosae. International Journal of Pharmaceutics. 601: 120593. PMID 33857587 DOI: 10.1016/j.ijpharm.2021.120593 |
0.788 |
|
| 2021 |
Brayden DJ, Stuettgen V. Sodium glycodeoxycholate and sodium deoxycholate as epithelial permeation enhancers: in vitro and ex vivo intestinal and buccal bioassays. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 159: 105737. PMID 33524502 DOI: 10.1016/j.ejps.2021.105737 |
0.343 |
|
| 2020 |
Twarog C, McCartney F, Harrison SM, Illel B, Fattal E, Brayden DJ. Comparison of the effects of the intestinal permeation enhancers, SNAC and sodium caprate (C): Isolated rat intestinal mucosae and sacs. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 158: 105685. PMID 33359131 DOI: 10.1016/j.ejps.2020.105685 |
0.811 |
|
| 2020 |
Maher S, Geoghegan C, Brayden DJ. Intestinal permeation enhancers to improve oral bioavailability of macromolecules: reasons for low efficacy in humans. Expert Opinion On Drug Delivery. 18: 273-300. PMID 32937089 DOI: 10.1080/17425247.2021.1825375 |
0.44 |
|
| 2020 |
Brayden DJ. Per Artursson's Major Contributions to the Caco-2 Cell Literature in Pharmaceutical Sciences. Journal of Pharmaceutical Sciences. 110: 12-16. PMID 32860800 DOI: 10.1016/J.Xphs.2020.08.016 |
0.35 |
|
| 2020 |
Fattah S, Ismaiel M, Murphy B, Rulikowska A, Frias JM, Winter DC, Brayden DJ. Salcaprozate sodium (SNAC) enhances permeability of octreotide across isolated rat and human intestinal epithelial mucosae in Ussing chambers. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 105509. PMID 32777258 DOI: 10.1016/J.Ejps.2020.105509 |
0.475 |
|
| 2020 |
Brayden DJ, Hill TA, Fairlie DP, Maher S, Mrsny RJ. Systemic delivery of peptides by the oral route: Formulation and medicinal chemistry approaches. Advanced Drug Delivery Reviews. PMID 32479930 DOI: 10.1016/J.Addr.2020.05.007 |
0.397 |
|
| 2020 |
Brayden DJ. Evolving peptides for oral intake. Nature Biomedical Engineering. PMID 32393890 DOI: 10.1038/S41551-020-0559-0 |
0.321 |
|
| 2020 |
Twarog C, Liu K, O'Brien PJ, Dawson KA, Fattal E, Illel B, Brayden DJ. A head-to-head Caco-2 assay comparison of the mechanisms of action of the intestinal permeation enhancers: SNAC and sodium caprate (C). European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 32387703 DOI: 10.1016/J.Ejpb.2020.04.023 |
0.435 |
|
| 2020 |
Skoulas D, Stuttgen V, Gaul R, Cryan SA, Brayden DJ, Heise A. Amphiphilic star polypept(o)ides as nanomeric vectors in mucosal drug delivery. Biomacromolecules. PMID 32343127 DOI: 10.1021/Acs.Biomac.0C00381 |
0.354 |
|
| 2020 |
Sladek S, McCartney F, Eskander M, Dunne DJ, Santos-Martinez MJ, Benetti F, Tajber L, Brayden DJ. An Enteric-Coated Polyelectrolyte Nanocomplex Delivers Insulin in Rat Intestinal Instillations when Combined with a Permeation Enhancer. Pharmaceutics. 12. PMID 32178442 DOI: 10.3390/Pharmaceutics12030259 |
0.778 |
|
| 2020 |
Stuettgen V, Brayden DJ. Investigations of Piperazine Derivatives as Intestinal Permeation Enhancers in Isolated Rat Intestinal Tissue Mucosae. The Aaps Journal. 22: 33. PMID 31989362 DOI: 10.1208/S12248-020-0416-9 |
0.489 |
|
| 2019 |
Hristov DR, McCartney F, Beirne J, Mahon E, Reid S, Bhattacharjee S, Penarier G, Werner U, Bazile DV, Brayden DJ. Silica-coated nanoparticles with a core of zinc, L-arginine and a peptide designed for oral delivery. Acs Applied Materials & Interfaces. PMID 31802658 DOI: 10.1021/Acsami.9B16104 |
0.788 |
|
| 2019 |
McCartney F, Rosa M, Brayden DJ. Evaluation of Sucrose Laurate as an Intestinal Permeation Enhancer for Macromolecules: Ex Vivo and In Vivo Studies. Pharmaceutics. 11. PMID 31683652 DOI: 10.3390/Pharmaceutics11110565 |
0.814 |
|
| 2019 |
McCartney F, Jannin V, Chevrier S, Boulghobra H, Hristov DR, Ritter N, Miolane C, Chavant Y, Demarne F, Brayden DJ. Labrasol® is an efficacious intestinal permeation enhancer across rat intestine: Ex vivo and in vivo rat studies. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 31401199 DOI: 10.1016/J.Jconrel.2019.08.008 |
0.81 |
|
| 2019 |
Brayden DJ, Baird AW. Stomaching Drug Delivery. The New England Journal of Medicine. 380: 1671-1673. PMID 31018074 DOI: 10.1056/Nejmcibr1901766 |
0.304 |
|
| 2019 |
Twarog C, Fattah S, Heade J, Maher S, Fattal E, Brayden DJ. Intestinal Permeation Enhancers for Oral Delivery of Macromolecules: A Comparison between Salcaprozate Sodium (SNAC) and Sodium Caprate (C). Pharmaceutics. 11. PMID 30781867 DOI: 10.3390/Pharmaceutics11020078 |
0.465 |
|
| 2019 |
Maher S, Brayden DJ, Casettari L, Illum L. Application of Permeation Enhancers in Oral Delivery of Macromolecules: An Update. Pharmaceutics. 11. PMID 30669434 DOI: 10.3390/Pharmaceutics11010041 |
0.392 |
|
| 2018 |
Bak A, Ashford M, Brayden DJ. Local delivery of macromolecules to treat diseases associated with the colon. Advanced Drug Delivery Reviews. PMID 30359631 DOI: 10.1016/J.Addr.2018.10.009 |
0.404 |
|
| 2018 |
Presas E, McCartney F, Sultan E, Hunger C, Nellen S, Alvarez CV, Werner U, Bazile D, Brayden DJ, O'Driscoll CM. Physicochemical, pharmacokinetic and pharmacodynamic analyses of amphiphilic cyclodextrin-based nanoparticles designed to enhance intestinal delivery of insulin. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30075208 DOI: 10.1016/J.Jconrel.2018.07.045 |
0.774 |
|
| 2018 |
Sladek S, Kearney C, Crean D, Brama PAJ, Tajber L, Fawcett K, Labberte MC, Leggett B, Brayden DJ. Intra-articular delivery of a nanocomplex comprising salmon calcitonin, hyaluronic acid, and chitosan using an equine model of joint inflammation. Drug Delivery and Translational Research. 8: 1421-1435. PMID 29947020 DOI: 10.1007/S13346-018-0557-X |
0.763 |
|
| 2018 |
Bhattacharjee S, Gaspar MM, Scholz D, Almeida AJ, Brayden DJ. Track analysis of the passage of rhodamine-labeled liposomes across porcine jejunal mucus in a microchannel device. Therapeutic Delivery. 9: 419-433. PMID 29722632 DOI: 10.4155/Tde-2017-0116 |
0.303 |
|
| 2018 |
Gleeson JP, Frías JM, Ryan SM, Brayden DJ. Sodium caprate enables the blood pressure-lowering effect of Ile-Pro-Pro and Leu-Lys-Pro in spontaneously hypertensive rats by indirectly overcoming PepT1 inhibition. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 29684535 DOI: 10.1016/J.Ejpb.2018.04.021 |
0.678 |
|
| 2018 |
Heade J, Maher S, Bleiel SB, Brayden DJ. Labrasol and Salts of Medium-Chain Fatty Acids Can Be Combined in Low Concentrations to Increase the Permeability of a Macromolecule Marker Across Isolated Rat Intestinal Mucosae. Journal of Pharmaceutical Sciences. 107: 1648-1655. PMID 29462634 DOI: 10.1016/J.Xphs.2018.02.012 |
0.453 |
|
| 2018 |
Maher S, Heade J, McCartney F, Waters S, Bleiel SB, Brayden DJ. Effects of surfactant-based permeation enhancers on mannitol permeability, histology, and electrogenic ion transport responses in excised rat colonic mucosae. International Journal of Pharmaceutics. PMID 29341916 DOI: 10.1016/J.Ijpharm.2018.01.008 |
0.799 |
|
| 2017 |
Fattah S, Brayden DJ. Progress in the formulation and delivery of somatostatin analogs for acromegaly. Therapeutic Delivery. 8: 867-878. PMID 28944744 DOI: 10.4155/Tde-2017-0064 |
0.417 |
|
| 2017 |
Morales JO, Brayden DJ. Buccal delivery of small molecules and biologics: of mucoadhesive polymers, films, and nanoparticles. Current Opinion in Pharmacology. 36: 22-28. PMID 28800417 DOI: 10.1016/J.Coph.2017.07.011 |
0.32 |
|
| 2017 |
Ahmad T, Gogarty M, Walsh E, Brayden DJ. A comparison of three Peyer's patch "M-like" cell culture models: particle uptake, bacterial interaction, and epithelial histology. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 28754262 DOI: 10.1016/J.Ejpb.2017.07.013 |
0.773 |
|
| 2017 |
Beloqui A, Brayden DJ, Artursson P, Préat V, des Rieux A. A human intestinal M-cell-like model for investigating particle, antigen and microorganism translocation. Nature Protocols. 12: 1387-1399. PMID 28617450 DOI: 10.1038/Nprot.2017.041 |
0.355 |
|
| 2017 |
Gleeson JP, Brayden DJ, Ryan SM. Evaluation of PepT1 transport of food-derived antihypertensive peptides, Ile-Pro-Pro and Leu-Lys-Pro using in vitro, ex vivo and in vivo transport models. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 28315445 DOI: 10.1016/J.Ejpb.2017.03.007 |
0.675 |
|
| 2016 |
Bhattacharjee S, Mahon E, Harrison SM, McGetrick J, Muniyappa M, Carrington SD, Brayden DJ. Nanoparticle passage through porcine jejunal mucus: microfluidics and rheology. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 27965167 DOI: 10.1016/J.Nano.2016.11.017 |
0.315 |
|
| 2016 |
Brayden DJ, Alonso MJ. Oral delivery of peptides: opportunities and issues for translation. Advanced Drug Delivery Reviews. 106: 193-195. PMID 27865345 DOI: 10.1016/J.Addr.2016.10.005 |
0.349 |
|
| 2016 |
Maher S, Medani M, Carballeira NN, Winter DC, Baird AW, Brayden DJ. Development of a Non-Aqueous Dispersion to Improve Intestinal Epithelial Flux of Poorly Permeable Macromolecules. The Aaps Journal. PMID 27739012 DOI: 10.1208/S12248-016-9996-9 |
0.495 |
|
| 2016 |
Aguirre TA, Aversa V, Rosa M, Guterres SS, Pohlmann AR, Coulter I, Brayden DJ. Coated minispheres of salmon calcitonin target rat intestinal regions to achieve systemic bioavailability: Comparison between intestinal instillation and oral gavage. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 27480451 DOI: 10.1016/J.Jconrel.2016.07.047 |
0.819 |
|
| 2016 |
Bzik VA, Brayden DJ. An Assessment of the Permeation Enhancer, 1-phenyl-piperazine (PPZ), on Paracellular Flux Across Rat Intestinal Mucosae in Ussing Chambers. Pharmaceutical Research. 33: 2506-16. PMID 27387171 DOI: 10.1007/S11095-016-1975-4 |
0.805 |
|
| 2016 |
Mrsny RJ, Brayden DJ. Introduction for the special issue on recent advances in drug delivery across tissue barriers. Tissue Barriers. 4: e1187981. PMID 27358759 DOI: 10.1080/21688370.2016.1187981 |
0.421 |
|
| 2016 |
McCartney F, Gleeson JP, Brayden DJ. Safety concerns over the use of intestinal permeation enhancers: A mini-review. Tissue Barriers. 4: e1176822. PMID 27358756 DOI: 10.1080/21688370.2016.1176822 |
0.817 |
|
| 2016 |
Maher S, Mrsny RJ, Brayden DJ. Intestinal permeation enhancers for oral peptide delivery. Advanced Drug Delivery Reviews. 106: 277-319. PMID 27320643 DOI: 10.1016/J.Addr.2016.06.005 |
0.454 |
|
| 2016 |
Aguirre TA, Teijeiro-Osorio D, Rosa M, Coulter IS, Alonso MJ, Brayden DJ. Current status of selected oral peptide technologies in advanced preclinical development and in clinical trials. Advanced Drug Delivery Reviews. PMID 26921819 DOI: 10.1016/J.Addr.2016.02.004 |
0.798 |
|
| 2016 |
Gleeson JP, Ryan SM, Brayden DJ. Oral delivery strategies for nutraceuticals: Delivery vehicles and absorption enhancers Trends in Food Science and Technology. 53: 90-101. DOI: 10.1016/J.Tifs.2016.05.007 |
0.673 |
|
| 2015 |
Aguirre TA, Rosa M, Coulter IS, Brayden DJ. In vitro and in vivo preclinical evaluation of a minisphere emulsion-based formulation (SmPill®) of salmon calcitonin. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 79: 102-11. PMID 26349051 DOI: 10.1016/J.Ejps.2015.09.001 |
0.811 |
|
| 2015 |
Gleeson JP, Heade J, Ryan SM, Brayden DJ. Stability, toxicity and intestinal permeation enhancement of two food-derived antihypertensive tripeptides, Ile-Pro-Pro and Leu-Lys-Pro. Peptides. 71: 1-7. PMID 26048090 DOI: 10.1016/J.Peptides.2015.05.009 |
0.709 |
|
| 2015 |
Brayden DJ, Maher S, Bahar B, Walsh E. Sodium caprate-induced increases in intestinal permeability and epithelial damage are prevented by misoprostol. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 94: 194-206. PMID 26026287 DOI: 10.1016/J.Ejpb.2015.05.013 |
0.813 |
|
| 2015 |
Brayden DJ, Cryan SA, Dawson KA, O'Brien PJ, Simpson JC. High-content analysis for drug delivery and nanoparticle applications. Drug Discovery Today. PMID 25908578 DOI: 10.1016/J.Drudis.2015.04.001 |
0.342 |
|
| 2014 |
Brayden DJ, Gleeson J, Walsh EG. A head-to-head multi-parametric high content analysis of a series of medium chain fatty acid intestinal permeation enhancers in Caco-2 cells. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 88: 830-39. PMID 25460147 DOI: 10.1016/J.Ejpb.2014.10.008 |
0.808 |
|
| 2014 |
Aguirre TA, Rosa M, Guterres SS, Pohlmann AR, Coulter I, Brayden DJ. Investigation of coco-glucoside as a novel intestinal permeation enhancer in rat models. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 88: 856-65. PMID 25445305 DOI: 10.1016/J.Ejpb.2014.10.013 |
0.831 |
|
| 2014 |
Maher S, Ryan B, Duffy A, Brayden DJ. Formulation strategies to improve oral peptide delivery Pharmaceutical Patent Analyst. 3: 313-336. PMID 24998290 DOI: 10.4155/Ppa.14.15 |
0.396 |
|
| 2014 |
Hubbard D, Ghandehari H, Brayden DJ. Transepithelial transport of PAMAM dendrimers across isolated rat jejunal mucosae in ussing chambers. Biomacromolecules. 15: 2889-95. PMID 24992090 DOI: 10.1021/Bm5004465 |
0.441 |
|
| 2014 |
Brayden DJ, Walsh E. Efficacious intestinal permeation enhancement induced by the sodium salt of 10-undecylenic acid, a medium chain fatty acid derivative. The Aaps Journal. 16: 1064-76. PMID 24961919 DOI: 10.1208/S12248-014-9634-3 |
0.819 |
|
| 2014 |
Welling SH, Hubálek F, Jacobsen J, Brayden DJ, Rahbek UL, Buckley ST. The role of citric acid in oral peptide and protein formulations: relationship between calcium chelation and proteolysis inhibition. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 86: 544-51. PMID 24384069 DOI: 10.1016/J.Ejpb.2013.12.017 |
0.357 |
|
| 2014 |
Finn R, Ahmad T, Coffey ET, Brayden DJ, Baird AW, Boyd A. Translocation of Vibrio parahaemolyticus across an in vitro M cell model. Fems Microbiology Letters. 350: 65-71. PMID 24188736 DOI: 10.1111/1574-6968.12323 |
0.305 |
|
| 2013 |
Petersen SB, Nielsen LG, Rahbek UL, Guldbrandt M, Brayden DJ. Colonic absorption of salmon calcitonin using tetradecyl maltoside (TDM) as a permeation enhancer. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 48: 726-34. PMID 23354154 DOI: 10.1016/J.Ejps.2013.01.009 |
0.488 |
|
| 2013 |
Coco R, Plapied L, Pourcelle V, Jérôme C, Brayden DJ, Schneider YJ, Préat V. Drug delivery to inflamed colon by nanoparticles: comparison of different strategies. International Journal of Pharmaceutics. 440: 3-12. PMID 22820482 DOI: 10.1016/J.Ijpharm.2012.07.017 |
0.335 |
|
| 2012 |
Maher S, Brayden DJ. Overcoming poor permeability: translating permeation enhancers for oral peptide delivery Drug Discovery Today: Technologies. 9. PMID 24064271 DOI: 10.1016/J.Ddtec.2011.11.006 |
0.434 |
|
| 2012 |
Medani M, Bzik VA, Rogers A, Collins D, Kennelly R, Winter DC, Brayden DJ, Baird AW. Zinc sulphate attenuates chloride secretion in human colonic mucosae in vitro. European Journal of Pharmacology. 696: 166-71. PMID 23022335 DOI: 10.1016/J.Ejphar.2012.09.017 |
0.795 |
|
| 2012 |
Petersen SB, Nolan G, Maher S, Rahbek UL, Guldbrandt M, Brayden DJ. Evaluation of alkylmaltosides as intestinal permeation enhancers: Comparison between rat intestinal mucosal sheets and Caco-2 monolayers European Journal of Pharmaceutical Sciences. 47: 701-712. PMID 22952065 DOI: 10.1016/J.Ejps.2012.08.010 |
0.501 |
|
| 2012 |
Mohan HM, Collins D, Maher S, Walsh EG, Winter DC, O'Brien PJ, Brayden DJ, Baird AW. The mycotoxin patulin increases colonic epithelial permeability in vitro. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 50: 4097-102. PMID 22906760 DOI: 10.1016/J.Fct.2012.07.036 |
0.825 |
|
| 2012 |
Brayden DJ, Bzik VA, Lewis AL, Illum L. CriticalSorbâ„¢ promotes permeation of flux markers across isolated rat intestinal mucosae and Caco-2 monolayers. Pharmaceutical Research. 29: 2543-54. PMID 22638869 DOI: 10.1007/S11095-012-0785-6 |
0.812 |
|
| 2012 |
Jones MW, Mantovani G, Blindauer CA, Ryan SM, Wang X, Brayden DJ, Haddleton DM. Direct peptide bioconjugation/PEGylation at tyrosine with linear and branched polymeric diazonium salts. Journal of the American Chemical Society. 134: 7406-13. PMID 22494012 DOI: 10.1021/Ja211855Q |
0.341 |
|
| 2012 |
Bzik VA, Medani M, Baird AW, Winter DC, Brayden DJ. Mechanisms of action of zinc on rat intestinal epithelial electrogenic ion secretion: insights into its antidiarrhoeal actions. The Journal of Pharmacy and Pharmacology. 64: 644-53. PMID 22471360 DOI: 10.1111/J.2042-7158.2011.01441.X |
0.805 |
|
| 2011 |
Walsh EG, Adamczyk BE, Chalasani KB, Maher S, O'Toole EB, Fox JS, Leonard TW, Brayden DJ. Oral delivery of macromolecules: rationale underpinning Gastrointestinal Permeation Enhancement Technology (GIPET). Therapeutic Delivery. 2: 1595-610. PMID 22833984 DOI: 10.4155/Tde.11.132 |
0.805 |
|
| 2011 |
Brayden DJ, Mrsny RJ. Oral peptide delivery: prioritizing the leading technologies. Therapeutic Delivery. 2: 1567-73. PMID 22833982 DOI: 10.4155/Tde.11.114 |
0.334 |
|
| 2011 |
Keely S, Feighery L, Campion DP, O'Brien L, Brayden DJ, Baird AW. Chloride-led disruption of the intestinal mucous layer impedes Salmonella invasion: evidence for an 'enteric tear' mechanism. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 28: 743-52. PMID 22178886 DOI: 10.1159/000335768 |
0.802 |
|
| 2011 |
Walsh EG, Maher S, Devocelle M, O'Brien PJ, Baird AW, Brayden DJ. High content analysis to determine cytotoxicity of the antimicrobial peptide, melittin and selected structural analogs. Peptides. 32: 1764-73. PMID 21703316 DOI: 10.1016/J.Peptides.2011.06.006 |
0.785 |
|
| 2011 |
Rawlinson LA, O'Gara JP, Jones DS, Brayden DJ. Resistance of Staphylococcus aureus to the cationic antimicrobial agent poly(2-(dimethylamino ethyl)methacrylate) (pDMAEMA) is influenced by cell-surface charge and hydrophobicity. Journal of Medical Microbiology. 60: 968-76. PMID 21393458 DOI: 10.1099/Jmm.0.025619-0 |
0.708 |
|
| 2011 |
Ryan SM, FrÃas JM, Wang X, Sayers CT, Haddleton DM, Brayden DJ. PK/PD modelling of comb-shaped PEGylated salmon calcitonin conjugates of differing molecular weights. Journal of Controlled Release : Official Journal of the Controlled Release Society. 149: 126-32. PMID 20946924 DOI: 10.1016/J.Jconrel.2010.10.004 |
0.341 |
|
| 2011 |
Medani M, Kennelly R, Collins D, Brayden D, Baird A, Winter D. Inhibition Of Electrogenic Chloride Transport By Basolateral Zinc In Perfused Human Colon Journal of Surgical Research. 165: 287. DOI: 10.1016/J.Jss.2010.11.397 |
0.326 |
|
| 2010 |
Wang X, Maher S, Brayden DJ. Restoration of rat colonic epithelium after in situ intestinal instillation of the absorption promoter, sodium caprate. Therapeutic Delivery. 1: 75-82. PMID 22816121 DOI: 10.4155/Tde.10.5 |
0.484 |
|
| 2010 |
Brayden DJ, Maher S. Oral absorption enhancement: taking the next steps in therapeutic delivery. Therapeutic Delivery. 1: 5-9. PMID 22816114 DOI: 10.4155/Tde.10.14 |
0.38 |
|
| 2010 |
Cheng WP, Thompson C, Ryan SM, Aguirre T, Tetley L, Brayden DJ. In vitro and in vivo characterisation of a novel peptide delivery system: amphiphilic polyelectrolyte-salmon calcitonin nanocomplexes. Journal of Controlled Release : Official Journal of the Controlled Release Society. 147: 289-97. PMID 20705108 DOI: 10.1016/J.Jconrel.2010.07.128 |
0.781 |
|
| 2010 |
Rawlinson LA, O'Brien PJ, Brayden DJ. High content analysis of cytotoxic effects of pDMAEMA on human intestinal epithelial and monocyte cultures. Journal of Controlled Release : Official Journal of the Controlled Release Society. 146: 84-92. PMID 20457190 DOI: 10.1016/J.Jconrel.2010.05.002 |
0.765 |
|
| 2010 |
Maher S, Devocelle M, Ryan S, McClean S, Brayden DJ. Impact of amino acid replacements on in vitro permeation enhancement and cytotoxicity of the intestinal absorption promoter, melittin. International Journal of Pharmaceutics. 387: 154-60. PMID 20025949 DOI: 10.1016/J.Ijpharm.2009.12.022 |
0.43 |
|
| 2010 |
Rawlinson LA, Ryan SM, Mantovani G, Syrett JA, Haddleton DM, Brayden DJ. Antibacterial effects of poly(2-(dimethylamino ethyl)methacrylate) against selected gram-positive and gram-negative bacteria. Biomacromolecules. 11: 443-53. PMID 20025269 DOI: 10.1021/Bm901166Y |
0.725 |
|
| 2009 |
Maher S, Leonard TW, Jacobsen J, Brayden DJ. Safety and efficacy of sodium caprate in promoting oral drug absorption: from in vitro to the clinic. Advanced Drug Delivery Reviews. 61: 1427-49. PMID 19800376 DOI: 10.1016/J.Addr.2009.09.006 |
0.45 |
|
| 2009 |
Maher S, Kennelly R, Bzik VA, Baird AW, Wang X, Winter D, Brayden DJ. Evaluation of intestinal absorption enhancement and local mucosal toxicity of two promoters. I. Studies in isolated rat and human colonic mucosae. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 38: 291-300. PMID 19737613 DOI: 10.1016/J.Ejps.2009.09.001 |
0.825 |
|
| 2009 |
Maher S, Wang X, Bzik V, McClean S, Brayden DJ. Evaluation of intestinal absorption and mucosal toxicity using two promoters. II. Rat instillation and perfusion studies. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 38: 301-11. PMID 19664704 DOI: 10.1016/J.Ejps.2009.07.011 |
0.816 |
|
| 2009 |
Ryan SM, Wang X, Mantovani G, Sayers CT, Haddleton DM, Brayden DJ. Conjugation of salmon calcitonin to a combed-shaped end functionalized poly(poly(ethylene glycol) methyl ether methacrylate) yields a bioactive stable conjugate. Journal of Controlled Release : Official Journal of the Controlled Release Society. 135: 51-9. PMID 19168100 DOI: 10.1016/J.Jconrel.2008.12.014 |
0.332 |
|
| 2009 |
Keely S, Ryan SM, Haddleton DM, Limer A, Mantovani G, Murphy EP, Colgan SP, Brayden DJ. Dexamethasone-pDMAEMA polymeric conjugates reduce inflammatory biomarkers in human intestinal epithelial monolayers. Journal of Controlled Release : Official Journal of the Controlled Release Society. 135: 35-43. PMID 19110018 DOI: 10.1016/J.Jconrel.2008.12.001 |
0.602 |
|
| 2008 |
Maher S, Brayden DJ, Feighery L, McClean S. Cracking the junction: update on the progress of gastrointestinal absorption enhancement in the delivery of poorly absorbed drugs. Critical Reviews in Therapeutic Drug Carrier Systems. 25: 117-68. PMID 18540837 DOI: 10.1615/Critrevtherdrugcarriersyst.V25.I2.10 |
0.804 |
|
| 2008 |
Ryan SM, Mantovani G, Wang X, Haddleton DM, Brayden DJ. Advances in PEGylation of important biotech molecules: delivery aspects. Expert Opinion On Drug Delivery. 5: 371-83. PMID 18426380 DOI: 10.1517/17425247.5.4.371 |
0.306 |
|
| 2008 |
Feighery L, Smyth A, Keely S, Baird AW, O'Connor WT, Callanan JJ, Brayden DJ. Increased intestinal permeability in rats subjected to traumatic frontal lobe percussion brain injury. The Journal of Trauma. 64: 131-7; discussion 13. PMID 18188111 DOI: 10.1097/Ta.0B013E3181568D9F |
0.778 |
|
| 2008 |
Feighery LM, Cochrane SW, Quinn T, Baird AW, O'Toole D, Owens SE, O'Donoghue D, Mrsny RJ, Brayden DJ. Myosin light chain kinase inhibition: correction of increased intestinal epithelial permeability in vitro. Pharmaceutical Research. 25: 1377-86. PMID 18163202 DOI: 10.1007/S11095-007-9527-6 |
0.778 |
|
| 2008 |
Feighery LM, Smith P, O'Mahony L, Fallon PG, Brayden DJ. Effects of Lactobacillus salivarius 433118 on intestinal inflammation, immunity status and in vitro colon function in two mouse models of inflammatory bowel disease. Digestive Diseases and Sciences. 53: 2495-506. PMID 18157694 DOI: 10.1007/S10620-007-0157-Y |
0.786 |
|
| 2008 |
Keely S, Rawlinson LA, Haddleton DM, Brayden DJ. A tertiary amino-containing polymethacrylate polymer protects mucus-covered intestinal epithelial monolayers against pathogenic challenge. Pharmaceutical Research. 25: 1193-201. PMID 18046631 DOI: 10.1007/S11095-007-9501-3 |
0.794 |
|
| 2008 |
Cox AB, Rawlinson LA, Baird AW, Bzik V, Brayden DJ. In vitro interactions between the oral absorption promoter, sodium caprate (C(10)) and S. typhimurium in rat intestinal ileal mucosae. Pharmaceutical Research. 25: 114-22. PMID 17546408 DOI: 10.1007/S11095-007-9354-9 |
0.823 |
|
| 2007 |
Maher S, Feighery L, Brayden DJ, McClean S. Melittin as a permeability enhancer II: in vitro investigations in human mucus secreting intestinal monolayers and rat colonic mucosae. Pharmaceutical Research. 24: 1346-56. PMID 17380268 DOI: 10.1007/S11095-007-9246-Z |
0.823 |
|
| 2007 |
Maher S, Feighery L, Brayden DJ, McClean S. Melittin as an epithelial permeability enhancer I: investigation of its mechanism of action in Caco-2 monolayers. Pharmaceutical Research. 24: 1336-45. PMID 17373574 DOI: 10.1007/S11095-007-9288-2 |
0.79 |
|
| 2006 |
Leonard TW, Lynch J, McKenna MJ, Brayden DJ. Promoting absorption of drugs in humans using medium-chain fatty acid-based solid dosage forms: GIPET. Expert Opinion On Drug Delivery. 3: 685-92. PMID 16948563 DOI: 10.1517/17425247.3.5.685 |
0.397 |
|
| 2006 |
Soni J, Baird AW, O'Brien LM, McElroy M, Callanan JJ, Bassett HF, Campion D, Brayden DJ. Rat, ovine and bovine Peyer's patches mounted in horizontal diffusion chambers display sampling function. Journal of Controlled Release : Official Journal of the Controlled Release Society. 115: 68-77. PMID 16884804 DOI: 10.1016/J.Jconrel.2006.06.021 |
0.76 |
|
| 2006 |
Limer AJ, Rullay AK, Miguel VS, Peinado C, Keely S, Fitzpatrick E, Carrington SD, Brayden D, Haddleton DM. Fluorescently tagged star polymers by living radical polymerisation for mucoadhesion and bioadhesion Reactive and Functional Polymers. 66: 51-64. DOI: 10.1016/J.Reactfunctpolym.2005.07.024 |
0.543 |
|
| 2005 |
Brayden DJ, Jepson MA, Baird AW. Keynote review: intestinal Peyer's patch M cells and oral vaccine targeting. Drug Discovery Today. 10: 1145-57. PMID 16182207 DOI: 10.1016/S1359-6446(05)03536-1 |
0.326 |
|
| 2005 |
Roth-Walter F, Bohle B, Schöll I, Untersmayr E, Scheiner O, Boltz-Nitulescu G, Gabor F, Brayden DJ, Jensen-Jarolim E. Targeting antigens to murine and human M-cells with Aleuria aurantia lectin-functionalized microparticles. Immunology Letters. 100: 182-8. PMID 15913790 DOI: 10.1016/J.Imlet.2005.03.020 |
0.311 |
|
| 2005 |
Keely S, Rullay A, Wilson C, Carmichael A, Carrington S, Corfield A, Haddleton DM, Brayden DJ. In vitro and ex vivo intestinal tissue models to measure mucoadhesion of poly (methacrylate) and N-trimethylated chitosan polymers. Pharmaceutical Research. 22: 38-49. PMID 15771228 DOI: 10.1007/S11095-004-9007-1 |
0.598 |
|
| 2004 |
Baird AW, Campion DP, O'Brien L, Brayden DJ. Oral delivery of pathogens from the intestine to the nervous system Journal of Drug Targeting. 12: 71-78. PMID 15203900 DOI: 10.1080/10611860410001693715 |
0.384 |
|
| 2004 |
Brayden DJ, Baird AW. Apical membrane receptors on intestinal M cells: potential targets for vaccine delivery. Advanced Drug Delivery Reviews. 56: 721-6. PMID 15063586 DOI: 10.1016/J.Addr.2003.10.036 |
0.334 |
|
| 2004 |
Brayden D. Pathogen invasion across intestine: mechanisms and potential exploitation Advanced Drug Delivery Reviews. 56: 717-719. DOI: 10.1016/J.Addr.2003.09.004 |
0.359 |
|
| 2003 |
Cochrane SW, O'Donoghue DP, Brayden DJ, Baird AW. In vitro inhibition of cytochalasin induced tight junction opening in human colon Gastroenterology. 124: A316. DOI: 10.1016/S0016-5085(03)81593-7 |
0.312 |
|
| 2002 |
Lo D, Hilbush B, Mah S, Brayden D, Byrne D, Higgins L, O'Mahony DJ. Catching target receptors for drug and vaccine delivery using TOGA gene expression profiling. Advanced Drug Delivery Reviews. 54: 1213-23. PMID 12393302 DOI: 10.1016/S0169-409X(02)00091-1 |
0.327 |
|
| 2002 |
Clark MA, Blair H, Liang L, Brey RN, Brayden D, Hirst BH. Targeting polymerised liposome vaccine carriers to intestinal M cells. Vaccine. 20: 208-17. PMID 11567766 DOI: 10.1016/S0264-410X(01)00258-4 |
0.308 |
|
| 2001 |
Le Ferrec E, Chesne C, Artusson P, Brayden D, Fabre G, Gires P, Guillou F, Rousset M, Rubas W, Scarino ML. In vitro models of the intestinal barrier. The report and recommendations of ECVAM Workshop 46. European Centre for the Validation of Alternative methods. Alternatives to Laboratory Animals : Atla. 29: 649-68. PMID 11709041 DOI: 10.1177/026119290102900604 |
0.335 |
|
| 2000 |
Gullberg E, Leonard M, Karlsson J, Hopkins AM, Brayden D, Baird AW, Artursson P. Expression of specific markers and particle transport in a new human intestinal M-cell model. Biochemical and Biophysical Research Communications. 279: 808-13. PMID 11162433 DOI: 10.1006/Bbrc.2000.4038 |
0.32 |
|
| 2000 |
Leonard M, Creed E, Brayden D, Baird AW. Iontophoresis-enhanced absorptive flux of polar molecules across intestinal tissue in vitro. Pharmaceutical Research. 17: 476-8. PMID 10870994 DOI: 10.1023/A:1007541423500 |
0.333 |
|
| 1998 |
McClean S, Prosser E, Meehan E, O'Malley D, Clarke N, Ramtoola Z, Brayden D. Binding and uptake of biodegradable poly-DL-lactide micro- and nanoparticles in intestinal epithelia. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 6: 153-63. PMID 9795038 DOI: 10.1016/S0928-0987(97)10007-0 |
0.381 |
|
| 1998 |
Brayden D, Creed E, O'Connell A, Leipold H, Agarwal R, Leone-Bay A. Heparin absorption across the intestine: effects of sodium N-[8-(2-hydroxybenzoyl)amino]caprylate in rat in situ intestinal instillations and in Caco-2 monolayers. Pharmaceutical Research. 14: 1772-9. PMID 9453067 DOI: 10.1023/A:1012192115828 |
0.427 |
|
| 1998 |
Brayden DJ, O'Mahony DJ. Novel oral drug delivery gateways for biotechnology products: polypeptides and vaccines Pharmaceutical Science & Technology Today. 1: 291-299. DOI: 10.1016/S1461-5347(98)00075-3 |
0.382 |
|
| 1997 |
Raoof A, Moriarty D, Brayden D, Corrigan OI, Cumming I, Butler J, Devane J. Comparison of methodologies for evaluating regional intestinal permeability. Advances in Experimental Medicine and Biology. 423: 181-9. PMID 9269494 DOI: 10.1007/978-1-4684-6036-0_16 |
0.33 |
|
| 1997 |
Baird AW, Taylor CT, Brayden DJ. Non-antibiotic anti-diarrhoeal drugs: factors affecting oral bioavailability of berberine and loperamide in intestinal tissue Advanced Drug Delivery Reviews. 23: 111-120. DOI: 10.1016/S0169-409X(96)00429-2 |
0.421 |
|
| 1996 |
Brayden D, Creed E, Meehan E, O'Malley K. Passive transepithelial diltiazem absorption across intestinal tissue leading to tight junction openings Journal of Controlled Release. 38: 193-203. DOI: 10.1016/0168-3659(95)00120-4 |
0.387 |
|
| 1995 |
Brayden DJ, Baird AW. A distinctive electrophysiological signature from the Peyer's patches of rabbit intestine. British Journal of Pharmacology. 113: 593-9. PMID 7530575 DOI: 10.1111/J.1476-5381.1994.Tb17031.X |
0.397 |
|
| 1993 |
Brayden DJ, Krouse ME, Law T, Wine JJ. Stilbenes stimulate T84 Cl- secretion by elevating Ca2+. The American Journal of Physiology. 264: G325-33. PMID 8447416 DOI: 10.1152/Ajpgi.1993.264.2.G325 |
0.538 |
|
| 1991 |
Wine JJ, Brayden DJ, Hagiwara G, Krouse ME, Law TC, Müller UJ, Solc CK, Ward CL, Widdicombe JH, Xia Y. Cystic fibrosis, the CFTR, and rectifying Cl- channels. Advances in Experimental Medicine and Biology. 290: 253-69; discussion 2. PMID 1719763 DOI: 10.1007/978-1-4684-5934-0_25 |
0.554 |
|
| 1991 |
Pickles RJ, Brayden DJ, Cuthbert AW. Synchronous transporting activity in epithelial cells in relation to intracellular calcium concentration. Proceedings. Biological Sciences. 245: 53-8. PMID 1682929 DOI: 10.1098/Rspb.1991.0087 |
0.566 |
|
| 1991 |
Brayden DJ, Pickles RJ, Cuthbert AW. Ion transport in cultured epithelia from human sweat glands: comparison of normal and cystic fibrosis tissues. British Journal of Pharmacology. 102: 57-64. PMID 1646063 DOI: 10.1111/J.1476-5381.1991.Tb12132.X |
0.587 |
|
| 1990 |
Brayden DJ, Cuthbert AW. A novel method for culturing sweat gland epithelia: comparison of normal and cystic fibrosis tissues. British Journal of Clinical Pharmacology. 29: 235-8. PMID 2306416 DOI: 10.1111/J.1365-2125.1990.Tb03625.X |
0.573 |
|
| 1990 |
Cuthbert AW, Brayden DJ, Dunne A, Smyth RL, Wallwork J. Altered sensitivity to amiloride in cystic fibrosis. Observations using cultured sweat glands British Journal of Clinical Pharmacology. 29: 227-234. PMID 2306415 DOI: 10.1111/J.1365-2125.1990.Tb03624.X |
0.553 |
|
| 1989 |
Brayden DJ, Cuthbert AW, Lee CM. Human eccrine sweat gland epithelial cultures express ductal characteristics. The Journal of Physiology. 405: 657-75. PMID 3255802 DOI: 10.1113/Jphysiol.1988.Sp017354 |
0.58 |
|
| 1989 |
Brayden DJ, Hanley MR, Thastrup O, Cuthbert AW. Thapsigargin, a new calcium-dependent epithelial anion secretagogue. British Journal of Pharmacology. 98: 809-16. PMID 2511993 DOI: 10.1111/J.1476-5381.1989.Tb14609.X |
0.567 |
|
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