| Year |
Citation |
Score |
| 2024 |
Komine O, Ohnuma S, Hinohara K, Hara Y, Shimada M, Akashi T, Watanabe S, Sobue A, Kawade N, Ogi T, Yamanaka K. Genetic background variation impacts microglial heterogeneity and disease progression in amyotrophic lateral sclerosis model mice. Iscience. 27: 108872. PMID 38318390 DOI: 10.1016/j.isci.2024.108872 |
0.31 |
|
| 2023 |
Adachi K, Miyata K, Chida Y, Hirose M, Morisaki Y, Yamanaka K, Misawa H. Depletion of perivascular macrophages delays ALS disease progression by ameliorating blood-spinal cord barrier impairment in SOD1 mice. Frontiers in Cellular Neuroscience. 17: 1291673. PMID 38077951 DOI: 10.3389/fncel.2023.1291673 |
0.405 |
|
| 2023 |
Oiwa K, Watanabe S, Onodera K, Iguchi Y, Kinoshita Y, Komine O, Sobue A, Okada Y, Katsuno M, Yamanaka K. Monomerization of TDP-43 is a key determinant for inducing TDP-43 pathology in amyotrophic lateral sclerosis. Science Advances. 9: eadf6895. PMID 37540751 DOI: 10.1126/sciadv.adf6895 |
0.396 |
|
| 2023 |
Yamashita H, Komine O, Fujimori-Tonou N, Yamanaka K. Corrigendum: Comprehensive expression analysis with cell-type-specific transcriptome in ALS-linked mutant SOD1 mice: Revisiting the active role of glial cells in disease. Frontiers in Cellular Neuroscience. 17: 1160444. PMID 36937183 DOI: 10.3389/fncel.2023.1160444 |
0.311 |
|
| 2023 |
Yamashita H, Komine O, Fujimori-Tonou N, Yamanaka K. Comprehensive expression analysis with cell-type-specific transcriptome in ALS-linked mutant SOD1 mice: Revisiting the active role of glial cells in disease. Frontiers in Cellular Neuroscience. 16: 1045647. PMID 36687517 DOI: 10.3389/fncel.2022.1045647 |
0.357 |
|
| 2021 |
Sakai S, Watanabe S, Komine O, Sobue A, Yamanaka K. Novel reporters of mitochondria-associated membranes (MAM), MAMtrackers, demonstrate MAM disruption as a common pathological feature in amyotrophic lateral sclerosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21688. PMID 34143516 DOI: 10.1096/fj.202100137R |
0.308 |
|
| 2020 |
Konishi H, Okamoto T, Hara Y, Komine O, Tamada H, Maeda M, Osako F, Kobayashi M, Nishiyama A, Kataoka Y, Takai T, Udagawa N, Jung S, Ozato K, Tamura T, ... ... Yamanaka K, et al. Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction. The Embo Journal. e104464. PMID 32959911 DOI: 10.15252/Embj.2020104464 |
0.325 |
|
| 2020 |
Amporndanai K, Rogers M, Watanabe S, Yamanaka K, O'Neill PM, Hasnain SS. Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis. Ebiomedicine. 59: 102980. PMID 32862101 DOI: 10.1016/J.Ebiom.2020.102980 |
0.484 |
|
| 2020 |
Watanabe S, Oiwa K, Murata Y, Komine O, Sobue A, Endo F, Takahashi E, Yamanaka K. ALS-linked TDP-43 knock-in mice exhibit splicing deregulation without neurodegeneration. Molecular Brain. 13: 8. PMID 31959210 DOI: 10.1186/S13041-020-0550-4 |
0.455 |
|
| 2019 |
Nishino K, Watanabe S, Shijie J, Murata Y, Oiwa K, Komine O, Endo F, Tsuiji H, Abe M, Sakimura K, Mishra A, Yamanaka K. Mice deficient in the C-terminal domain of TAR DNA-binding protein 43 develop age-dependent motor dysfunction associated with impaired Notch1-Akt signaling pathway. Acta Neuropathologica Communications. 7: 118. PMID 31345270 DOI: 10.1186/S40478-019-0776-5 |
0.579 |
|
| 2018 |
Trias E, Barbeito L, Yamanaka K. Phenotypic heterogeneity of astrocytes in motor neuron disease. Clinical & Experimental Neuroimmunology. 9: 225-234. PMID 30555538 DOI: 10.1111/Cen3.12476 |
0.406 |
|
| 2018 |
Komine O, Yamashita H, Fujimori-Tonou N, Koike M, Jin S, Moriwaki Y, Endo F, Watanabe S, Uematsu S, Akira S, Uchiyama Y, Takahashi R, Misawa H, Yamanaka K. Innate immune adaptor TRIF deficiency accelerates disease progression of ALS mice with accumulation of aberrantly activated astrocytes. Cell Death and Differentiation. PMID 29568058 DOI: 10.1038/S41418-018-0098-3 |
0.428 |
|
| 2018 |
Tokuda E, Nomura T, Ohara S, Watanabe S, Yamanaka K, Morisaki Y, Misawa H, Furukawa Y. A copper-deficient form of mutant cu/Zn-superoxide dismutase as an early pathological species in amyotrophic lateral sclerosis. Biochimica Et Biophysica Acta. PMID 29551730 DOI: 10.1016/J.Bbadis.2018.03.015 |
0.417 |
|
| 2018 |
Yamanaka K, Komine O. The multi-dimensional roles of astrocytes in ALS. Neuroscience Research. 126: 31-38. PMID 29054467 DOI: 10.1016/J.Neures.2017.09.011 |
0.476 |
|
| 2017 |
Watanabe S, Komine O, Endo F, Wakasugi K, Yamanaka K. Intracerebroventricular administration of Cystatin C ameliorates disease in SOD1-linked amyotrophic lateral sclerosis mice. Journal of Neurochemistry. PMID 29282717 DOI: 10.1111/Jnc.14285 |
0.521 |
|
| 2017 |
Watanabe-Matsumoto S, Moriwaki Y, Okuda T, Ohara S, Yamanaka K, Abe Y, Yasui M, Misawa H. Dissociation of blood-brain barrier disruption and disease manifestation in an aquaporin-4-deficient mouse model of amyotrophic lateral sclerosis. Neuroscience Research. PMID 29154923 DOI: 10.1016/J.Neures.2017.11.001 |
0.438 |
|
| 2017 |
Tsuiji H, Inoue I, Takeuchi M, Furuya A, Yamakage Y, Watanabe S, Koike M, Hattori M, Yamanaka K. TDP-43 accelerates age-dependent degeneration of interneurons. Scientific Reports. 7: 14972. PMID 29097807 DOI: 10.1038/S41598-017-14966-W |
0.393 |
|
| 2017 |
Yamanaka K. [Roles of Microglia in Neurodegenerative Diseases]. Brain and Nerve = Shinkei Kenkyu No Shinpo. 69: 999-1005. PMID 28900062 DOI: 10.11477/Mf.1416200859 |
0.454 |
|
| 2017 |
Yamasaki T, Deki-Arima N, Kaneko A, Miyamura N, Iwatsuki M, Matsuoka M, Fujimori-Tonou N, Okamoto-Uchida Y, Hirayama J, Marth JD, Yamanashi Y, Kawasaki H, Yamanaka K, Penninger JM, Shibata S, et al. Age-dependent motor dysfunction due to neuron-specific disruption of stress-activated protein kinase MKK7. Scientific Reports. 7: 7348. PMID 28779160 DOI: 10.1038/S41598-017-07845-X |
0.386 |
|
| 2017 |
Tokuda E, Anzai I, Nomura T, Toichi K, Watanabe M, Ohara S, Watanabe S, Yamanaka K, Morisaki Y, Misawa H, Furukawa Y. Immunochemical characterization on pathological oligomers of mutant Cu/Zn-superoxide dismutase in amyotrophic lateral sclerosis. Molecular Neurodegeneration. 12: 2. PMID 28057013 DOI: 10.1186/S13024-016-0145-9 |
0.464 |
|
| 2017 |
Endo F, Kurita T, Yamanaka K. Astrocyte-derived extracellular vesicles contribute to the propagation of pathogenic protein in ALS Journal of the Neurological Sciences. 381: 203-204. DOI: 10.1016/J.Jns.2017.08.582 |
0.374 |
|
| 2017 |
Nishino K, Watanabe S, Komine O, Endo F, Yamanaka K. Mice heterozygously lacking C-terminal domain of TDP-43 show age-dependent motor dysfunction Journal of the Neurological Sciences. 381: 570. DOI: 10.1016/J.Jns.2017.08.1604 |
0.322 |
|
| 2016 |
Anzai I, Tokuda E, Mukaiyama A, Akiyama S, Endo F, Yamanaka K, Misawa H, Furukawa Y. A misfolded dimer of Cu/Zn-superoxide dismutase leading to pathological oligomerization in amyotrophic lateral sclerosis. Protein Science : a Publication of the Protein Society. PMID 27977888 DOI: 10.1002/Pro.3094 |
0.407 |
|
| 2016 |
Watanabe S, Ilieva H, Tamada H, Nomura H, Komine O, Endo F, Jin S, Mancias P, Kiyama H, Yamanaka K. Mitochondria-associated membrane collapse is a common pathomechanism in SIGMAR1- and SOD1-linked ALS. Embo Molecular Medicine. PMID 27821430 DOI: 10.15252/Emmm.201606403 |
0.47 |
|
| 2016 |
Amanullah A, Upadhyay A, Chhangani D, Joshi V, Mishra R, Yamanaka K, Mishra A. Proteasomal Dysfunction Induced by Diclofenac Engenders Apoptosis through Mitochondrial Pathway. Journal of Cellular Biochemistry. PMID 27487200 DOI: 10.1002/Jcb.25666 |
0.487 |
|
| 2016 |
Morisaki Y, Niikura M, Watanabe M, Onishi K, Tanabe S, Moriwaki Y, Okuda T, Ohara S, Murayama S, Takao M, Uchida S, Yamanaka K, Misawa H. Selective Expression of Osteopontin in ALS-resistant Motor Neurons is a Critical Determinant of Late Phase Neurodegeneration Mediated by Matrix Metalloproteinase-9. Scientific Reports. 6: 27354. PMID 27264390 DOI: 10.1038/Srep27354 |
0.392 |
|
| 2016 |
Lasiene J, Komine O, Fujimori-Tonou N, Powers B, Endo F, Watanabe S, Shijie J, Ravits J, Horner P, Misawa H, Yamanaka K. Neuregulin 1 confers neuroprotection in SOD1-linked amyotrophic lateral sclerosis mice via restoration of C-boutons of spinal motor neurons. Acta Neuropathologica Communications. 4: 15. PMID 26891847 DOI: 10.1186/S40478-016-0286-7 |
0.455 |
|
| 2015 |
Komine O, Yamanaka K. Neuroinflammation in motor neuron disease. Nagoya Journal of Medical Science. 77: 537-549. PMID 26663933 DOI: 10.1111/Cen3.12309 |
0.485 |
|
| 2015 |
Chhangani D, Endo F, Amanullah A, Upadhyay A, Watanabe S, Mishra R, Yamanaka K, Mishra A. Mahogunin ring finger 1 confers cytoprotection against mutant SOD1 aggresomes and is defective in an ALS mouse model. Neurobiology of Disease. PMID 26607786 DOI: 10.1016/J.Nbd.2015.11.017 |
0.646 |
|
| 2015 |
Endo F, Yamanaka K. Astrocytic TGF-β1: detrimental factor in ALS. Oncotarget. 6: 15728-9. PMID 26164079 DOI: 10.18632/Oncotarget.4786 |
0.417 |
|
| 2015 |
Endo F, Komine O, Fujimori-Tonou N, Katsuno M, Jin S, Watanabe S, Sobue G, Dezawa M, Wyss-Coray T, Yamanaka K. Astrocyte-derived TGF-β1 accelerates disease progression in ALS mice by interfering with the neuroprotective functions of microglia and T cells. Cell Reports. 11: 592-604. PMID 25892237 DOI: 10.1016/J.Celrep.2015.03.053 |
0.363 |
|
| 2015 |
Heneka MT, Carson MJ, El Khoury J, Landreth GE, Brosseron F, Feinstein DL, Jacobs AH, Wyss-Coray T, Vitorica J, Ransohoff RM, Herrup K, Frautschy SA, Finsen B, Brown GC, Verkhratsky A, ... Yamanaka K, et al. Neuroinflammation in Alzheimer's disease. The Lancet. Neurology. 14: 388-405. PMID 25792098 DOI: 10.1016/S1474-4422(15)70016-5 |
0.345 |
|
| 2014 |
Endo F, Yamanaka K. [Neuroinflammation in amyotrophic lateral sclerosis]. Rinshō Shinkeigaku = Clinical Neurology. 54: 1128-31. PMID 25672727 DOI: 10.5692/Clinicalneurol.54.1128 |
0.375 |
|
| 2014 |
Yamanaka K. [Biochemical abnormality of mutant TDP-43 protein]. Rinshō Shinkeigaku = Clinical Neurology. 54: 1148-50. PMID 25519967 DOI: 10.5692/Clinicalneurol.54.1148 |
0.436 |
|
| 2014 |
Watanabe S, Hayakawa T, Wakasugi K, Yamanaka K. Cystatin C protects neuronal cells against mutant copper-zinc superoxide dismutase-mediated toxicity. Cell Death & Disease. 5: e1497. PMID 25356866 DOI: 10.1038/Cddis.2014.459 |
0.495 |
|
| 2014 |
Watanabe S, Ageta-Ishihara N, Nagatsu S, Takao K, Komine O, Endo F, Miyakawa T, Misawa H, Takahashi R, Kinoshita M, Yamanaka K. SIRT1 overexpression ameliorates a mouse model of SOD1-linked amyotrophic lateral sclerosis via HSF1/HSP70i chaperone system. Molecular Brain. 7: 62. PMID 25167838 DOI: 10.1186/S13041-014-0062-1 |
0.413 |
|
| 2014 |
Austin JA, Wright GS, Watanabe S, Grossmann JG, Antonyuk SV, Yamanaka K, Hasnain SS. Disease causing mutants of TDP-43 nucleic acid binding domains are resistant to aggregation and have increased stability and half-life. Proceedings of the National Academy of Sciences of the United States of America. 111: 4309-14. PMID 24591609 DOI: 10.1073/Pnas.1317317111 |
0.425 |
|
| 2014 |
Nomura T, Watanabe S, Kaneko K, Yamanaka K, Nukina N, Furukawa Y. Intranuclear aggregation of mutant FUS/TLS as a molecular pathomechanism of amyotrophic lateral sclerosis. The Journal of Biological Chemistry. 289: 1192-202. PMID 24280224 DOI: 10.1074/Jbc.M113.516492 |
0.401 |
|
| 2013 |
Furukawa Y, Kaneko K, Watanabe S, Yamanaka K, Nukina N. Intracellular seeded aggregation of mutant Cu,Zn-superoxide dismutase associated with amyotrophic lateral sclerosis. Febs Letters. 587: 2500-5. PMID 23831581 DOI: 10.1016/J.Febslet.2013.06.046 |
0.336 |
|
| 2013 |
Iguchi Y, Katsuno M, Niwa J, Takagi S, Ishigaki S, Ikenaka K, Kawai K, Watanabe H, Yamanaka K, Takahashi R, Misawa H, Sasaki S, Tanaka F, Sobue G. Loss of TDP-43 causes age-dependent progressive motor neuron degeneration. Brain : a Journal of Neurology. 136: 1371-82. PMID 23449777 DOI: 10.1093/Brain/Awt029 |
0.44 |
|
| 2013 |
Toichi K, Yamanaka K, Furukawa Y. Disulfide scrambling describes the oligomer formation of superoxide dismutase (SOD1) proteins in the familial form of amyotrophic lateral sclerosis. The Journal of Biological Chemistry. 288: 4970-80. PMID 23264618 DOI: 10.1074/Jbc.M112.414235 |
0.389 |
|
| 2013 |
Tsuiji H, Iguchi Y, Furuya A, Kataoka A, Hatsuta H, Atsuta N, Tanaka F, Hashizume Y, Akatsu H, Murayama S, Sobue G, Yamanaka K. Spliceosome integrity is defective in the motor neuron diseases ALS and SMA. Embo Molecular Medicine. 5: 221-34. PMID 23255347 DOI: 10.1002/Emmm.201202303 |
0.461 |
|
| 2013 |
Watanabe S, Kaneko K, Yamanaka K. Accelerated disease onset with stabilized familial amyotrophic lateral sclerosis (ALS)-linked mutant TDP-43 proteins. The Journal of Biological Chemistry. 288: 3641-54. PMID 23235148 DOI: 10.1074/Jbc.M112.433615 |
0.462 |
|
| 2013 |
Mishra A, Maheshwari M, Chhangani D, Fujimori-Tonou N, Endo F, Joshi AP, Jana NR, Yamanaka K. E6-AP association promotes SOD1 aggresomes degradation and suppresses toxicity. Neurobiology of Aging. 34: 1310.e11-23. PMID 23040663 DOI: 10.1016/J.Neurobiolaging.2012.08.016 |
0.608 |
|
| 2013 |
Nomura T, Watanabe S, Kaneko K, Yamanaka K, Nukina N, Furukawa Y. 1P065 A new pathomechanism of amyotrophic lateral sclerosis regulated by aggregation of FUS/TLS protein(01C. Protein:Property,Poster) Seibutsu Butsuri. 53: S116. DOI: 10.2142/Biophys.53.S116_5 |
0.326 |
|
| 2012 |
Yamanaka K. [Is "non-cell autonomous" neuron death common to neurodegenerative diseases?]. Rinsho Shinkeigaku = Clinical Neurology. 52: 1329-31. PMID 23196608 DOI: 10.5692/Clinicalneurol.52.1329 |
0.387 |
|
| 2012 |
Yamashita H, Fujimori N, Ito H, Iguchi Y, Atsuta N, Tanaka F, Sobue G, Takahashi R, Yamanaka K. Microarray Analysis in Spinal Cords of Sporadic ALS Patients with Cell-Type Specific Transcriptome (P05.168) Neurology. 78. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P05.168 |
0.409 |
|
| 2011 |
Yamanaka K. [Glial pathology in amyotrophic lateral sclerosis]. Rinsho Shinkeigaku = Clinical Neurology. 51: 1192-4. PMID 22277531 DOI: 10.5692/Clinicalneurol.51.1192 |
0.516 |
|
| 2011 |
Lasiene J, Yamanaka K. Glial cells in amyotrophic lateral sclerosis. Neurology Research International. 2011: 718987. PMID 21766027 DOI: 10.1155/2011/718987 |
0.513 |
|
| 2011 |
Takeuchi H, Mizoguchi H, Doi Y, Jin S, Noda M, Liang J, Li H, Zhou Y, Mori R, Yasuoka S, Li E, Parajuli B, Kawanokuchi J, Sonobe Y, Sato J, ... Yamanaka K, et al. Blockade of gap junction hemichannel suppresses disease progression in mouse models of amyotrophic lateral sclerosis and Alzheimer's disease Plos One. 6. PMID 21712989 DOI: 10.1371/Journal.Pone.0021108 |
0.441 |
|
| 2011 |
Furukawa Y, Kaneko K, Watanabe S, Yamanaka K, Nukina N. A seeding reaction recapitulates intracellular formation of Sarkosyl-insoluble transactivation response element (TAR) DNA-binding protein-43 inclusions. The Journal of Biological Chemistry. 286: 18664-72. PMID 21454603 DOI: 10.1074/Jbc.M111.231209 |
0.392 |
|
| 2011 |
Tsuiji H, Kataoka A, Yamanaka K. Regulation of spliceosome by ALS-causative gene TDP-43 Neuroscience Research. 71: e102. DOI: 10.1016/J.Neures.2011.07.436 |
0.349 |
|
| 2011 |
Yamashita H, Fujimori N, Kataoka A, Iguchi Y, Atsuta N, Tanaka F, Sobue G, Ito H, Takahashi R, Yamanaka K. Microarray analysis in spinal cords of sporadic ALS patients with cell-type specific transcriptome Neuroscience Research. 71. DOI: 10.1016/J.Neures.2011.07.1276 |
0.329 |
|
| 2011 |
Yamanaka K. Active roles of glial cells in non-cell autonomous neurodegeneration in ALS Neuroscience Research. 71: e8. DOI: 10.1016/J.Neures.2011.07.027 |
0.367 |
|
| 2010 |
Israelson A, Arbel N, Da Cruz S, Ilieva H, Yamanaka K, Shoshan-Barmatz V, Cleveland DW. Misfolded mutant SOD1 directly inhibits VDAC1 conductance in a mouse model of inherited ALS. Neuron. 67: 575-87. PMID 20797535 DOI: 10.1016/J.Neuron.2010.07.019 |
0.464 |
|
| 2010 |
Furukawa Y, Kaneko K, Yamanaka K, Nukina N. Mutation-dependent polymorphism of Cu,Zn-superoxide dismutase aggregates in the familial form of amyotrophic lateral sclerosis. The Journal of Biological Chemistry. 285: 22221-31. PMID 20404329 DOI: 10.1074/Jbc.M110.113597 |
0.362 |
|
| 2010 |
Yamanaka K. The role of glial cells in ALS Neuroscience Research. 68: e29. DOI: 10.1016/J.Neures.2010.07.369 |
0.381 |
|
| 2009 |
Lobsiger CS, Boillee S, McAlonis-Downes M, Khan AM, Feltri ML, Yamanaka K, Cleveland DW. Schwann cells expressing dismutase active mutant SOD1 unexpectedly slow disease progression in ALS mice. Proceedings of the National Academy of Sciences of the United States of America. 106: 4465-70. PMID 19251638 DOI: 10.1073/Pnas.0813339106 |
0.503 |
|
| 2009 |
Cleveland DW, Yamanaka K, Bomont P. Gigaxonin controls vimentin organization through a tubulin chaperone-independent pathway. Human Molecular Genetics. 18: 1384-94. PMID 19168853 DOI: 10.1093/Hmg/Ddp044 |
0.389 |
|
| 2009 |
Yamanaka K. Controlling neuroinflammation through glial cells as viable target for the therapy to slow neurodegeneration in ALS Neuroscience Research. 65: S29. DOI: 10.1016/J.Neures.2009.09.1662 |
0.334 |
|
| 2008 |
Ilieva HS, Yamanaka K, Malkmus S, Kakinohana O, Yaksh T, Marsala M, Cleveland DW. Mutant dynein (Loa) triggers proprioceptive axon loss that extends survival only in the SOD1 ALS model with highest motor neuron death. Proceedings of the National Academy of Sciences of the United States of America. 105: 12599-604. PMID 18719118 DOI: 10.1073/Pnas.0805422105 |
0.441 |
|
| 2008 |
Furukawa Y, Kaneko K, Yamanaka K, O'Halloran TV, Nukina N. Complete loss of post-translational modifications triggers fibrillar aggregation of SOD1 in the familial form of amyotrophic lateral sclerosis. The Journal of Biological Chemistry. 283: 24167-76. PMID 18552350 DOI: 10.1074/Jbc.M802083200 |
0.393 |
|
| 2008 |
Yamanaka K, Boillee S, Roberts EA, Garcia ML, McAlonis-Downes M, Mikse OR, Cleveland DW, Goldstein LS. Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 7594-9. PMID 18492803 DOI: 10.1073/Pnas.0802556105 |
0.438 |
|
| 2008 |
Yamanaka K, Chun SJ, Boillee S, Fujimori-Tonou N, Yamashita H, Gutmann DH, Takahashi R, Misawa H, Cleveland DW. Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis. Nature Neuroscience. 11: 251-3. PMID 18246065 DOI: 10.1038/Nn2047 |
0.507 |
|
| 2007 |
Yamanaka K. [Animal models of amyotrophic lateral sclerosis]. Rinsho Shinkeigaku = Clinical Neurology. 47: 934-7. PMID 18210840 |
0.398 |
|
| 2007 |
Yamanaka K, Yamashita H. [ALS and microglia--a player for non-cell-autonomous neuron death]. Brain and Nerve = Shinkei Kenkyu No Shinpo. 59: 1163-70. PMID 17969357 |
0.429 |
|
| 2007 |
Yamashita H, Kawamata J, Okawa K, Kanki R, Nakamizo T, Hatayama T, Yamanaka K, Takahashi R, Shimohama S. Heat-shock protein 105 interacts with and suppresses aggregation of mutant Cu/Zn superoxide dismutase: clues to a possible strategy for treating ALS. Journal of Neurochemistry. 102: 1497-505. PMID 17403032 DOI: 10.1111/J.1471-4159.2007.04534.X |
0.43 |
|
| 2007 |
Furukawa Y, Kaneko K, Yamanaka K, Nukina N. 3P059 Elimination of post-translational modifications in SOD1 leads to form pathological amyloid-like aggregates in familial ALS(Proteins-stability, folding, and other physicochemical properties,Oral Presentations) Seibutsu Butsuri. 47: S217. DOI: 10.2142/Biophys.47.S217_4 |
0.363 |
|
| 2006 |
Miller TM, Kim SH, Yamanaka K, Hester M, Umapathi P, Arnson H, Rizo L, Mendell JR, Gage FH, Cleveland DW, Kaspar BK. Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 103: 19546-51. PMID 17164329 DOI: 10.1073/Pnas.0609411103 |
0.397 |
|
| 2006 |
Smith RA, Miller TM, Yamanaka K, Monia BP, Condon TP, Hung G, Lobsiger CS, Ward CM, McAlonis-Downes M, Wei H, Wancewicz EV, Bennett CF, Cleveland DW. Antisense oligonucleotide therapy for neurodegenerative disease. The Journal of Clinical Investigation. 116: 2290-6. PMID 16878173 DOI: 10.1172/Jci25424 |
0.447 |
|
| 2006 |
Yamanaka K, Miller TM, McAlonis-Downes M, Chun SJ, Cleveland DW. Progressive spinal axonal degeneration and slowness in ALS2-deficient mice. Annals of Neurology. 60: 95-104. PMID 16802286 DOI: 10.1002/Ana.20888 |
0.448 |
|
| 2006 |
Boillée S, Yamanaka K, Lobsiger CS, Copeland NG, Jenkins NA, Kassiotis G, Kollias G, Cleveland DW. Onset and progression in inherited ALS determined by motor neurons and microglia. Science (New York, N.Y.). 312: 1389-92. PMID 16741123 DOI: 10.1126/Science.1123511 |
0.472 |
|
| 2006 |
Eymard-Pierre E, Yamanaka K, Haeussler M, Kress W, Gauthier-Barichard F, Combes P, Cleveland DW, Boespflug-Tanguy O. Novel missense mutation in ALS2 gene results in infantile ascending hereditary spastic paralysis. Annals of Neurology. 59: 976-80. PMID 16718699 DOI: 10.1002/Ana.20879 |
0.394 |
|
| 2005 |
Yamanaka K, Cleveland DW. Determinants of rapid disease progression in ALS. Neurology. 65: 1859-60. PMID 16380607 DOI: 10.1212/01.Wnl.0000192717.25980.B5 |
0.488 |
|
| 2005 |
Miller TM, Kaspar BK, Kops GJ, Yamanaka K, Christian LJ, Gage FH, Cleveland DW. Virus-delivered small RNA silencing sustains strength in amyotrophic lateral sclerosis. Annals of Neurology. 57: 773-6. PMID 15852369 DOI: 10.1002/Ana.20453 |
0.366 |
|
| 2003 |
Yamanaka K, Vande Velde C, Eymard-Pierre E, Bertini E, Boespflug-Tanguy O, Cleveland DW. Unstable mutants in the peripheral endosomal membrane component ALS2 cause early-onset motor neuron disease. Proceedings of the National Academy of Sciences of the United States of America. 100: 16041-6. PMID 14668431 DOI: 10.1073/Pnas.2635267100 |
0.459 |
|
| 1999 |
Iwai K, Yamanaka K, Kamura T, Minato N, Conaway RC, Conaway JW, Klausner RD, Pause A. Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex. Proceedings of the National Academy of Sciences of the United States of America. 96: 12436-41. PMID 10535940 DOI: 10.1073/Pnas.96.22.12436 |
0.331 |
|
| 1999 |
Gonen H, Bercovich B, Orian A, Carrano A, Takizawa C, Yamanaka K, Pagano M, Iwai K, Ciechanover A. Identification of the ubiquitin carrier proteins, E2s, involved in signal-induced conjugation and subsequent degradation of IκBα Journal of Biological Chemistry. 274: 14823-14830. PMID 10329681 DOI: 10.1074/Jbc.274.21.14823 |
0.321 |
|
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