| Year |
Citation |
Score |
| 2023 |
Ragunathan P, Shuyi Ng P, Singh S, Poh WH, Litty D, Kalia NP, Larsson S, Harikishore A, Rice SA, Ingham PW, Müller V, Moraski G, Miller MJ, Dick T, Pethe K, et al. GaMF1.39's antibiotic efficacy and its enhanced antitubercular activity in combination with clofazimine, Telacebec, ND-011992, or TBAJ-876. Microbiology Spectrum. e0228223. PMID 37982630 DOI: 10.1128/spectrum.02282-23 |
0.372 |
|
| 2023 |
Harikishore A, Mathiyazakan V, Pethe K, Grüber G. Novel targets and inhibitors of the cytochrome oxidase to foster anti-tuberculosis drug discovery. Expert Opinion On Drug Discovery. 1-11. PMID 37332221 DOI: 10.1080/17460441.2023.2224553 |
0.377 |
|
| 2023 |
Lee BS, Singh S, Pethe K. Inhibiting respiration as a novel antibiotic strategy. Current Opinion in Microbiology. 74: 102327. PMID 37235914 DOI: 10.1016/j.mib.2023.102327 |
0.334 |
|
| 2023 |
Mathiyazakan V, Wong CF, Harikishore A, Pethe K, Grüber G. Cryo-Electron Microscopy Structure of the s Cytochrome : Supercomplex and a Novel Inhibitor Targeting Subunit Cytochrome I. Antimicrobial Agents and Chemotherapy. e0153122. PMID 37158740 DOI: 10.1128/aac.01531-22 |
0.31 |
|
| 2022 |
Lee BS, Pethe K. Telacebec: an investigational antibiotic for the treatment of tuberculosis (TB). Expert Opinion On Investigational Drugs. PMID 35034512 DOI: 10.1080/13543784.2022.2030309 |
0.349 |
|
| 2021 |
Sorayah R, Moraski GC, Barkan D, Pethe K. The QcrB Inhibitors TB47 and Telacebec Do Not Potentiate the Activity of Clofazimine in Mycobacterium abscessus. Antimicrobial Agents and Chemotherapy. 65: e0096421. PMID 34543090 DOI: 10.1128/AAC.00964-21 |
0.363 |
|
| 2021 |
Ngan JYG, Pasunooti S, Tse W, Meng W, Ngan SFC, Jia H, Lin JQ, Ng SW, Jaafa MT, Cho SLS, Lim J, Koh HQV, Abdul Ghani N, Pethe K, Sze SK, et al. HflX is a GTPase that controls hypoxia-induced replication arrest in slow-growing mycobacteria. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33723035 DOI: 10.1073/pnas.2006717118 |
0.301 |
|
| 2020 |
Lee BS, Hards K, Engelhart CA, Hasenoehrl EJ, Kalia NP, Mackenzie JS, Sviriaeva E, Chong SMS, Manimekalai MSS, Koh VH, Chan J, Xu J, Alonso S, Miller MJ, Steyn AJC, ... ... Pethe K, et al. Dual inhibition of the terminal oxidases eradicates antibiotic-tolerant Mycobacterium tuberculosis. Embo Molecular Medicine. e13207. PMID 33283973 DOI: 10.15252/emmm.202013207 |
0.367 |
|
| 2020 |
Chauffour A, Robert J, Veziris N, Aubry A, Pethe K, Jarlier V. Telacebec (Q203)-containing intermittent oral regimens sterilized mice infected with Mycobacterium ulcerans after only 16 doses. Plos Neglected Tropical Diseases. 14: e0007857. PMID 32866170 DOI: 10.1371/Journal.Pntd.0007857 |
0.319 |
|
| 2020 |
Sviriaeva E, Subramanian Manimekalai MS, Grüber G, Pethe K. Features and Functional Importance of Key Residues of the Cytochrome Oxidase. Acs Infectious Diseases. 6: 1697-1707. PMID 32379966 DOI: 10.1021/Acsinfecdis.9B00449 |
0.324 |
|
| 2020 |
Hotra A, Ragunathan P, Ng PS, Seankongsuk P, Harikishore A, Sarathy JP, Geok SW, Lakshmanan U, Sae-Lao P, Kalia NP, Shin J, Kalyanasundaram R, Anbarasu S, Parthasarathy K, Pradeep CN, ... ... Pethe K, et al. Discovery of a novel Mycobacterial F-ATP synthase inhibitor and its potency in combination with diarylquinolines. Angewandte Chemie (International Ed. in English). PMID 32337801 DOI: 10.1002/Anie.202002546 |
0.389 |
|
| 2020 |
Chong S, Manimekalai MSS, Sarathy JP, Williams ZC, Harold LK, Cook GM, Dick T, Pethe K, Bates RW, Grüber G. Anti-tuberculosis activity of the anti-malaria cytochrome bcc oxidase inhibitor SCR0911. Acs Infectious Diseases. PMID 32092260 DOI: 10.1021/Acsinfecdis.9B00408 |
0.494 |
|
| 2020 |
Lee BS, Sviriaeva E, Pethe K. Targeting the cytochrome oxidases for drug development in mycobacteria. Progress in Biophysics and Molecular Biology. PMID 32081616 DOI: 10.1016/J.Pbiomolbio.2020.02.001 |
0.437 |
|
| 2020 |
Si Z, Lim HW, Tay MYF, Du Y, Ruan L, Qiu H, Reghu S, Chen Y, Tiong WS, Marimuthu K, De PP, Ng OT, Zhu Y, Gan YH, Chi YR, ... ... Pethe K, et al. A glycosylated cationic block poly(beta-peptide) reverses intrinsic antibiotic resistance in all ESKAPE Gram-negative bacteria. Angewandte Chemie (International Ed. in English). PMID 32011781 DOI: 10.1002/Anie.201914304 |
0.307 |
|
| 2020 |
Lupien A, Foo CS, Savina S, Vocat A, Piton J, Monakhova N, Benjak A, Lamprecht DA, Steyn AJC, Pethe K, Makarov VA, Cole ST. New 2-Ethylthio-4-methylaminoquinazoline derivatives inhibiting two subunits of cytochrome bc1 in Mycobacterium tuberculosis. Plos Pathogens. 16: e1008270. PMID 31971990 DOI: 10.1371/Journal.Ppat.1008270 |
0.486 |
|
| 2020 |
Foo CS, Pethe K, Lupien A. Oxidative phosphorylation — an update on a new, essential target space for drug discovery in mycobacterium tuberculosis Applied Sciences. 10: 2339. DOI: 10.3390/App10072339 |
0.402 |
|
| 2019 |
Poh W, Ab Rahman N, Ostrovski Y, Sznitman J, Pethe K, Loo SCJ. Active pulmonary targeting against tuberculosis (TB) via triple-encapsulation of Q203, bedaquiline and superparamagnetic iron oxides (SPIOs) in nanoparticle aggregates. Drug Delivery. 26: 1039-1048. PMID 31691600 DOI: 10.1080/10717544.2019.1676841 |
0.385 |
|
| 2019 |
Zhang K, Du Y, Si Z, Liu Y, Turvey ME, Raju C, Keogh D, Ruan L, Jothy SL, Reghu S, Marimuthu K, De PP, Ng OT, Mediavilla JR, Kreiswirth BN, ... ... Pethe K, et al. Enantiomeric glycosylated cationic block co-beta-peptides eradicate Staphylococcus aureus biofilms and antibiotic-tolerant persisters. Nature Communications. 10: 4792. PMID 31636263 DOI: 10.1038/S41467-019-12702-8 |
0.345 |
|
| 2019 |
Sorayah R, Manimekalai MSS, Shin SJ, Koh WJ, Grüber G, Pethe K. Naturally-occurring polymorphisms in QcrB are responsible for resistance to Telacebec in Mycobacterium abscessus. Acs Infectious Diseases. PMID 31599569 DOI: 10.1021/Acsinfecdis.9B00322 |
0.413 |
|
| 2019 |
Kalia NP, Shi Lee B, Ab Rahman NB, Moraski GC, Miller MJ, Pethe K. Carbon metabolism modulates the efficacy of drugs targeting the cytochrome bc:aa in Mycobacterium tuberculosis. Scientific Reports. 9: 8608. PMID 31197236 DOI: 10.1038/S41598-019-44887-9 |
0.42 |
|
| 2018 |
Scherr N, Bieri R, Thomas SS, Chauffour A, Kalia NP, Schneide P, Ruf MT, Lamelas A, Manimekalai MSS, Grüber G, Ishii N, Suzuki K, Tanner M, Moraski GC, Miller MJ, ... ... Pethe K, et al. Targeting the Mycobacterium ulcerans cytochrome bc:aa for the treatment of Buruli ulcer. Nature Communications. 9: 5370. PMID 30560872 DOI: 10.1038/S41467-018-07804-8 |
0.424 |
|
| 2018 |
Lee BS, Kalia NP, Jin XEF, Hasenoehrl EJ, Berney M, Pethe K. Inhibitors of energy metabolism interfere with antibiotic-induced death in mycobacteria. The Journal of Biological Chemistry. PMID 30530783 DOI: 10.1074/Jbc.Ra118.005732 |
0.415 |
|
| 2018 |
Bouvier G, Simenel C, Jang J, Kalia NP, Choi I, Nilges M, Pethe K, Izadi-Pruneyre N. Target engagement and binding mode of an anti-tuberculosis drug to its bacterial target deciphered in whole living cells by NMR. Biochemistry. PMID 30521325 DOI: 10.1021/Acs.Biochem.8B00975 |
0.379 |
|
| 2018 |
Foo CS, Lupien A, Kienle M, Vocat A, Benjak A, Sommer R, Lamprecht DA, Steyn AJC, Pethe K, Piton J, Altmann KH, Cole ST. Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of Mycobacterium tuberculosis. Mbio. 9. PMID 30301850 DOI: 10.1128/Mbio.01276-18 |
0.472 |
|
| 2018 |
Lee BS, Pethe K. Therapeutic potential of promiscuous targets in Mycobacterium tuberculosis. Current Opinion in Pharmacology. 42: 22-26. PMID 30015177 DOI: 10.1016/J.Coph.2018.06.006 |
0.42 |
|
| 2017 |
Hou Z, Shankar YV, Liu Y, Ding F, Subramanion JL, Ravikumar V, Zamudio-Vázquez R, Keogh D, Lim H, Tay MYF, Bhattacharjya S, Rice SA, Shi J, Duan H, Liu XW, ... ... Pethe K, et al. Nanoparticles of Short Cationic Peptidopolysaccharide Self-Assembled by Hydrogen Bonding with Antibacterial Effect against Multi-Drug Resistant Bacteria. Acs Applied Materials & Interfaces. PMID 29028315 DOI: 10.1021/Acsami.7B12120 |
0.3 |
|
| 2017 |
Dupont C, Viljoen A, Thomas S, Roquet-Banères F, Herrmann JL, Pethe K, Kremer L. Bedaquiline inhibits the ATP synthase in Mycobacterium abscessus and is effective in infected zebrafish. Antimicrobial Agents and Chemotherapy. PMID 28807917 DOI: 10.1128/Aac.01225-17 |
0.45 |
|
| 2017 |
Kalia NP, Hasenoehrl EJ, Ab Rahman NB, Koh VH, Ang MLT, Sajorda DR, Hards K, Grüber G, Alonso S, Cook GM, Berney M, Pethe K. Exploiting the synthetic lethality between terminal respiratory oxidases to kill Mycobacterium tuberculosis and clear host infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 28652330 DOI: 10.1073/Pnas.1706139114 |
0.471 |
|
| 2017 |
Cook GM, Hards K, Dunn E, Heikal A, Nakatani Y, Greening C, Crick DC, Fontes FL, Pethe K, Hasenoehrl E, Berney M. Oxidative Phosphorylation as a Target Space for Tuberculosis: Success, Caution, and Future Directions. Microbiology Spectrum. 5. PMID 28597820 DOI: 10.1128/Microbiolspec.Tbtb2-0014-2016 |
0.477 |
|
| 2017 |
Ang MLT, Zainul Rahim SZ, de Sessions PF, Lin W, Koh V, Pethe K, Hibberd ML, Alonso S. EthA/R-Independent Killing of Mycobacterium tuberculosis by Ethionamide. Frontiers in Microbiology. 8: 710. PMID 28487681 DOI: 10.3389/Fmicb.2017.00710 |
0.359 |
|
| 2016 |
Murima P, Zimmermann M, Chopra T, Pojer F, Fonti G, Dal Peraro M, Alonso S, Sauer U, Pethe K, McKinney JD. A rheostat mechanism governs the bifurcation of carbon flux in mycobacteria. Nature Communications. 7: 12527. PMID 27555519 DOI: 10.1038/Ncomms12527 |
0.349 |
|
| 2016 |
Ang ML, Pethe K. Contribution of high-content imaging technologies to the development of anti-infective drugs. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 27272127 DOI: 10.1002/Cyto.A.22885 |
0.328 |
|
| 2015 |
Ang ML, Murima P, Pethe K. Next-generation antimicrobials: from chemical biology to first-in-class drugs. Archives of Pharmacal Research. 38: 1702-17. PMID 26259630 DOI: 10.1007/S12272-015-0645-0 |
0.376 |
|
| 2015 |
Kim MS, Jang J, Ab Rahman NB, Pethe K, Berry EA, Huang LS. Isolation and Characterization of a Hybrid Respiratory Supercomplex Consisting of Mycobacterium tuberculosis Cytochrome bcc and Mycobacterium smegmatis Cytochrome aa3. The Journal of Biological Chemistry. 290: 14350-60. PMID 25861988 DOI: 10.1074/Jbc.M114.624312 |
0.521 |
|
| 2015 |
Silva-Miranda M, Ekaza E, Breiman A, Asehnoune K, Barros-Aguirre D, Pethe K, Ewann F, Brodin P, Ballell-Pages L, Altare F. High-content screening technology combined with a human granuloma model as a new approach to evaluate the activities of drugs against Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. 59: 693-7. PMID 25348525 DOI: 10.1128/Aac.03705-14 |
0.431 |
|
| 2014 |
Xia X, Pethe K, Kim R, Ballell L, Barros D, Cechetto J, Jeon H, Kim K, Garcia-Bennett AE. Encapsulation of Anti-Tuberculosis Drugs within Mesoporous Silica and Intracellular Antibacterial Activities. Nanomaterials (Basel, Switzerland). 4: 813-826. PMID 28344250 DOI: 10.3390/Nano4030813 |
0.446 |
|
| 2014 |
Murima P, McKinney JD, Pethe K. Targeting bacterial central metabolism for drug development Chemistry and Biology. 21: 1423-1432. PMID 25442374 DOI: 10.1016/J.Chembiol.2014.08.020 |
0.375 |
|
| 2014 |
Kang S, Kim RY, Seo MJ, Lee S, Kim YM, Seo M, Seo JJ, Ko Y, Choi I, Jang J, Nam J, Park S, Kang H, Kim HJ, Kim J, ... ... Pethe K, et al. Lead optimization of a novel series of imidazo[1,2-a]pyridine amides leading to a clinical candidate (Q203) as a multi- and extensively-drug-resistant anti-tuberculosis agent. Journal of Medicinal Chemistry. 57: 5293-305. PMID 24870926 DOI: 10.1021/Jm5003606 |
0.43 |
|
| 2014 |
Ang ML, Zainul Rahim SZ, Siti ZZ, Shui G, Dianiškova P, Madacki J, Lin W, Koh VH, Martinez Gomez JM, Sudarkodi S, Bendt A, Wenk M, Mikušová K, Korduláková J, Pethe K, et al. An ethA-ethR-deficient Mycobacterium bovis BCG mutant displays increased adherence to mammalian cells and greater persistence in vivo, which correlate with altered mycolic acid composition. Infection and Immunity. 82: 1850-9. PMID 24566628 DOI: 10.1128/Iai.01332-13 |
0.485 |
|
| 2014 |
MartÃnez Gómez JM, Koh VH, Yan B, Lin W, Ang ML, Rahim SZ, Pethe K, Schwarz H, Alonso S. Role of the CD137 ligand (CD137L) signaling pathway during Mycobacterium tuberculosis infection. Immunobiology. 219: 78-86. PMID 24091276 DOI: 10.1016/J.Imbio.2013.08.009 |
0.353 |
|
| 2013 |
Yokokawa F, Wang G, Chan WL, Ang SH, Wong J, Ma I, Rao SP, Manjunatha U, Lakshminarayana SB, Herve M, Kounde C, Tan BH, Thayalan P, Ng SH, Nanjundappa M, ... ... Pethe K, et al. Discovery of tetrahydropyrazolopyrimidine carboxamide derivatives as potent and orally active antitubercular agents. Acs Medicinal Chemistry Letters. 4: 451-5. PMID 24900693 DOI: 10.1021/Ml400071A |
0.402 |
|
| 2013 |
Rao SP, Lakshminarayana SB, Kondreddi RR, Herve M, Camacho LR, Bifani P, Kalapala SK, Jiricek J, Ma NL, Tan BH, Ng SH, Nanjundappa M, Ravindran S, Seah PG, Thayalan P, ... ... Pethe K, et al. Indolcarboxamide is a preclinical candidate for treating multidrug-resistant tuberculosis. Science Translational Medicine. 5: 214ra168. PMID 24307692 DOI: 10.1126/Scitranslmed.3007355 |
0.454 |
|
| 2013 |
Pethe K, Bifani P, Jang J, Kang S, Park S, Ahn S, Jiricek J, Jung J, Jeon HK, Cechetto J, Christophe T, Lee H, Kempf M, Jackson M, Lenaerts AJ, et al. Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis. Nature Medicine. 19: 1157-60. PMID 23913123 DOI: 10.1038/Nm.3262 |
0.451 |
|
| 2013 |
Zheng J, Rubin EJ, Bifani P, Mathys V, Lim V, Au M, Jang J, Nam J, Dick T, Walker JR, Pethe K, Camacho LR. para-Aminosalicylic acid is a prodrug targeting dihydrofolate reductase in Mycobacterium tuberculosis. The Journal of Biological Chemistry. 288: 23447-56. PMID 23779105 DOI: 10.1074/Jbc.M113.475798 |
0.394 |
|
| 2013 |
Phong WY, Lin W, Rao SP, Dick T, Alonso S, Pethe K. Characterization of phosphofructokinase activity in Mycobacterium tuberculosis reveals that a functional glycolytic carbon flow is necessary to limit the accumulation of toxic metabolic intermediates under hypoxia. Plos One. 8: e56037. PMID 23409118 DOI: 10.1371/Journal.Pone.0056037 |
0.391 |
|
| 2012 |
Lin W, Mathys V, Ang EL, Koh VH, MartÃnez Gómez JM, Ang ML, Zainul Rahim SZ, Tan MP, Pethe K, Alonso S. Urease activity represents an alternative pathway for Mycobacterium tuberculosis nitrogen metabolism. Infection and Immunity. 80: 2771-9. PMID 22645285 DOI: 10.1128/Iai.06195-11 |
0.441 |
|
| 2012 |
Mak PA, Rao SP, Ping Tan M, Lin X, Chyba J, Tay J, Ng SH, Tan BH, Cherian J, Duraiswamy J, Bifani P, Lim V, Lee BH, Ling Ma N, Beer D, ... ... Pethe K, et al. A high-throughput screen to identify inhibitors of ATP homeostasis in non-replicating Mycobacterium tuberculosis. Acs Chemical Biology. 7: 1190-7. PMID 22500615 DOI: 10.1021/Cb2004884 |
0.464 |
|
| 2011 |
Schmitt EK, Riwanto M, Sambandamurthy V, Roggo S, Miault C, Zwingelstein C, Krastel P, Noble C, Beer D, Rao SP, Au M, Niyomrattanakit P, Lim V, Zheng J, Jeffery D, ... Pethe K, et al. The natural product cyclomarin kills Mycobacterium tuberculosis by targeting the ClpC1 subunit of the caseinolytic protease. Angewandte Chemie (International Ed. in English). 50: 5889-91. PMID 21563281 DOI: 10.1002/Anie.201101740 |
0.403 |
|
| 2010 |
Tan MP, Sequeira P, Lin WW, Phong WY, Cliff P, Ng SH, Lee BH, Camacho L, Schnappinger D, Ehrt S, Dick T, Pethe K, Alonso S. Nitrate respiration protects hypoxic Mycobacterium tuberculosis against acid- and reactive nitrogen species stresses. Plos One. 5: e13356. PMID 21048946 DOI: 10.1371/Journal.Pone.0013356 |
0.415 |
|
| 2010 |
Pethe K, Sequeira PC, Agarwalla S, Rhee K, Kuhen K, Phong WY, Patel V, Beer D, Walker JR, Duraiswamy J, Jiricek J, Keller TH, Chatterjee A, Tan MP, Ujjini M, et al. A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy. Nature Communications. 1: 57. PMID 20975714 DOI: 10.1038/Ncomms1060 |
0.474 |
|
| 2010 |
Marrero J, Rhee KY, Schnappinger D, Pethe K, Ehrt S. Gluconeogenic carbon flow of tricarboxylic acid cycle intermediates is critical for Mycobacterium tuberculosis to establish and maintain infection. Proceedings of the National Academy of Sciences of the United States of America. 107: 9819-24. PMID 20439709 DOI: 10.1073/Pnas.1000715107 |
0.381 |
|
| 2010 |
Gengenbacher M, Rao SP, Pethe K, Dick T. Nutrient-starved, non-replicating Mycobacterium tuberculosis requires respiration, ATP synthase and isocitrate lyase for maintenance of ATP homeostasis and viability. Microbiology (Reading, England). 156: 81-7. PMID 19797356 DOI: 10.1099/Mic.0.033084-0 |
0.421 |
|
| 2009 |
Low KL, Rao PS, Shui G, Bendt AK, Pethe K, Dick T, Wenk MR. Triacylglycerol utilization is required for regrowth of in vitro hypoxic nonreplicating Mycobacterium bovis bacillus Calmette-Guerin. Journal of Bacteriology. 191: 5037-43. PMID 19525349 DOI: 10.1128/Jb.00530-09 |
0.337 |
|
| 2008 |
Rao SP, Alonso S, Rand L, Dick T, Pethe K. The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 11945-50. PMID 18697942 DOI: 10.1073/Pnas.0711697105 |
0.421 |
|
| 2008 |
Rao SP, Camacho L, Huat Tan B, Boon C, Russel DG, Dick T, Pethe K. Recombinase-based reporter system and antisense technology to study gene expression and essentiality in hypoxic nonreplicating mycobacteria. Fems Microbiology Letters. 284: 68-75. PMID 18544099 DOI: 10.1111/J.1574-6968.2008.01193.X |
0.353 |
|
| 2008 |
Boshoff HI, Xu X, Tahlan K, Dowd CS, Pethe K, Camacho LR, Park TH, Yun CS, Schnappinger D, Ehrt S, Williams KJ, Barry CE. Biosynthesis and recycling of nicotinamide cofactors in mycobacterium tuberculosis. An essential role for NAD in nonreplicating bacilli. The Journal of Biological Chemistry. 283: 19329-41. PMID 18490451 DOI: 10.1074/Jbc.M800694200 |
0.478 |
|
| 2007 |
Shui G, Bendt AK, Pethe K, Dick T, Wenk MR. Sensitive profiling of chemically diverse bioactive lipids. Journal of Lipid Research. 48: 1976-84. PMID 17565170 DOI: 10.1194/Jlr.M700060-Jlr200 |
0.314 |
|
| 2007 |
Alonso S, Pethe K, Russell DG, Purdy GE. Lysosomal killing of Mycobacterium mediated by ubiquitin-derived peptides is enhanced by autophagy. Proceedings of the National Academy of Sciences of the United States of America. 104: 6031-6. PMID 17389386 DOI: 10.1073/Pnas.0700036104 |
0.542 |
|
| 2006 |
Owens RM, Hsu FF, VanderVen BC, Purdy GE, Hesteande E, Giannakas P, Sacchettini JC, McKinney JD, Hill PJ, Belisle JT, Butcher BA, Pethe K, Russell DG. M. tuberculosis Rv2252 encodes a diacylglycerol kinase involved in the biosynthesis of phosphatidylinositol mannosides (PIMs). Molecular Microbiology. 60: 1152-63. PMID 16689792 DOI: 10.1111/J.1365-2958.2006.05174.X |
0.678 |
|
| 2005 |
Peirs P, Lefèvre P, Boarbi S, Wang XM, Denis O, Braibant M, Pethe K, Locht C, Huygen K, Content J. Mycobacterium tuberculosis with disruption in genes encoding the phosphate binding proteins PstS1 and PstS2 is deficient in phosphate uptake and demonstrates reduced in vivo virulence. Infection and Immunity. 73: 1898-902. PMID 15731097 DOI: 10.1128/Iai.73.3.1898-1902.2005 |
0.422 |
|
| 2004 |
Pethe K, Swenson DL, Alonso S, Anderson J, Wang C, Russell DG. Isolation of Mycobacterium tuberculosis mutants defective in the arrest of phagosome maturation. Proceedings of the National Academy of Sciences of the United States of America. 101: 13642-7. PMID 15340136 DOI: 10.1073/Pnas.0401657101 |
0.592 |
|
| 2004 |
Temmerman S, Pethe K, Parra M, Alonso S, Rouanet C, Pickett T, Drowart A, Debrie AS, Delogu G, Menozzi FD, Sergheraert C, Brennan MJ, Mascart F, Locht C. Methylation-dependent T cell immunity to Mycobacterium tuberculosis heparin-binding hemagglutinin. Nature Medicine. 10: 935-41. PMID 15300244 DOI: 10.1038/Nm1090 |
0.369 |
|
| 2002 |
Pethe K, Bifani P, Drobecq H, Sergheraert C, Debrie AS, Locht C, Menozzi FD. Mycobacterial heparin-binding hemagglutinin and laminin-binding protein share antigenic methyllysines that confer resistance to proteolysis. Proceedings of the National Academy of Sciences of the United States of America. 99: 10759-64. PMID 12149464 DOI: 10.1073/Pnas.162246899 |
0.353 |
|
| 2002 |
Alonso S, Reveneau N, Pethe K, Locht C. Eighty-kilodalton N-terminal moiety of Bordetella pertussis filamentous hemagglutinin: adherence, immunogenicity, and protective role. Infection and Immunity. 70: 4142-7. PMID 12117922 DOI: 10.1128/Iai.70.8.4142-4147.2002 |
0.307 |
|
| 2002 |
Menozzi FD, Pethe K, Bifani P, Soncin F, Brennan MJ, Locht C. Enhanced bacterial virulence through exploitation of host glycosaminoglycans. Molecular Microbiology. 43: 1379-86. PMID 11971262 DOI: 10.1046/J.1365-2958.2002.02841.X |
0.373 |
|
| 2002 |
Ewann F, Jackson M, Pethe K, Cooper A, Mielcarek N, Ensergueix D, Gicquel B, Locht C, Supply P. Transient requirement of the PrrA-PrrB two-component system for early intracellular multiplication of Mycobacterium tuberculosis. Infection and Immunity. 70: 2256-63. PMID 11953357 DOI: 10.1128/Iai.70.5.2256-2263.2002 |
0.42 |
|
| 2002 |
Menozzi FD, Debrie AS, Tissier JP, Locht C, Pethe K, Raze D. Interaction of human Tamm-Horsfall glycoprotein with Bordetella pertussis toxin. Microbiology (Reading, England). 148: 1193-1201. PMID 11932463 DOI: 10.1099/00221287-148-4-1193 |
0.321 |
|
| 2002 |
Masungi C, Temmerman S, Van Vooren JP, Drowart A, Pethe K, Menozzi FD, Locht C, Mascart F. Differential T and B cell responses against Mycobacterium tuberculosis heparin-binding hemagglutinin adhesin in infected healthy individuals and patients with tuberculosis. The Journal of Infectious Diseases. 185: 513-20. PMID 11865404 DOI: 10.1086/338833 |
0.393 |
|
| 2001 |
Alonso S, Pethe K, Mielcarek N, Raze D, Locht C. Role of ADP-Ribosyltransferase Activity of Pertussis Toxin in Toxin- Adhesin Redundancy with Filamentous Hemagglutinin during Bordetella pertussis Infection Infection and Immunity. 69: 6038-6043. PMID 11553541 DOI: 10.1128/Iai.69.10.6038-6043.2001 |
0.301 |
|
| 2001 |
Pethe K, Alonso S, Biet F, Delogu G, Brennan MJ, Locht C, Menozzi FD. The heparin-binding haemagglutinin of M. tuberculosis is required for extrapulmonary dissemination Nature. 412: 190-194. PMID 11449276 DOI: 10.1038/35084083 |
0.471 |
|
| 2001 |
Pethe K, Puech V, Daffé M, Josenhans C, Drobecq H, Locht C, Menozzi FD. Mycobacterium smegmatis laminin-binding glycoprotein shares epitopes with Mycobacterium tuberculosis heparin-binding haemagglutinin Molecular Microbiology. 39: 89-99. PMID 11123691 DOI: 10.1046/J.1365-2958.2001.02206.X |
0.402 |
|
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