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James Arthur Olzmann - Publications

Affiliations: 
University of California, Berkeley, Berkeley, CA, United States 
Area:
Cell biology, organelle biogenesis, proteomic dynamics, lipid homeostasis, lipid droplets, lipotoxicity
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25/73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Riepe C, Wąchalska M, Deol KK, Amaya AK, Porteus MH, Olzmann JA, Kopito RR. Small molecule correctors divert CFTR-F508del from ERAD by stabilizing sequential folding states. Molecular Biology of the Cell. mbcE23080336. PMID 38019608 DOI: 10.1091/mbc.E23-08-0336  0.589
2023 Riepe C, Wąchalska M, Deol KK, Amaya AK, Porteus MH, Olzmann JA, Kopito RR. Small molecule correctors divert CFTR-F508del from ERAD by stabilizing sequential folding states. Biorxiv : the Preprint Server For Biology. PMID 37745470 DOI: 10.1101/2023.09.15.556420  0.59
2023 Roberts MA, Deol KK, Mathiowetz AJ, Lange M, Leto DE, Stevenson J, Hashemi SH, Morgens DW, Easter E, Heydari K, Nalls MA, Bassik MC, Kampmann M, Kopito RR, Faghri F, ... Olzmann JA, et al. Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation. Developmental Cell. PMID 37494933 DOI: 10.1016/j.devcel.2023.07.001  0.561
2022 Chen S, Roberts MA, Chen CY, Markmiller S, Wei HG, Yeo GW, Granneman JG, Olzmann JA, Ferro-Novick S. VPS13A and VPS13C Influence Lipid Droplet Abundance. Contact (Thousand Oaks (Ventura County, Calif.)). 5. PMID 36147729 DOI: 10.1177/25152564221125613  0.345
2020 Roberts MA, Olzmann JA. Protein Quality Control and Lipid Droplet Metabolism. Annual Review of Cell and Developmental Biology. 36: 115-139. PMID 33021827 DOI: 10.1146/annurev-cellbio-031320-101827  0.349
2020 Liang JR, Lingeman E, Luong T, Ahmed S, Muhar M, Nguyen T, Olzmann JA, Corn JE. A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation. Cell. PMID 32160526 DOI: 10.1016/J.Cell.2020.02.017  0.354
2019 Morris SNS, Olzmann JA. A Tense Situation: Maintaining ER Homeostasis during Lipid Droplet Budding. Developmental Cell. 50: 1-2. PMID 31265808 DOI: 10.1016/j.devcel.2019.06.005  0.312
2018 Bersuker K, Olzmann JA. In Close Proximity: The Lipid Droplet Proteome and Crosstalk With the Endoplasmic Reticulum. Contact (Thousand Oaks (Ventura County, Calif.)). 1. PMID 30101213 DOI: 10.1177/2515256418768996  0.382
2018 Huang EY, To M, Tran E, Dionisio LTA, Cho HJ, Baney KLM, Pataki CI, Olzmann JA. A VCP inhibitor substrate trapping approach (VISTA) enables proteomic profiling of endogenous ERAD substrates. Molecular Biology of the Cell. PMID 29514927 DOI: 10.1091/mbc.E17-08-0514  0.416
2017 Bersuker K, Peterson CWH, To M, Sahl SJ, Savikhin V, Grossman EA, Nomura DK, Olzmann JA. A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes. Developmental Cell. PMID 29275994 DOI: 10.1016/J.Devcel.2017.11.020  0.337
2017 Bersuker K, Olzmann JA. Establishing the lipid droplet proteome: Mechanisms of lipid droplet protein targeting and degradation. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. 1862: 1166-1177. PMID 28627435 DOI: 10.1016/j.bbalip.2017.06.006  0.333
2017 Hwang J, Walczak CP, Shaler TA, Olzmann JA, Zhang L, Elias JE, Kopito RR. Characterization of protein complexes of the endoplasmic reticulum associated degradation E3 ubiquitin ligase Hrd1. The Journal of Biological Chemistry. PMID 28411238 DOI: 10.1074/Jbc.M117.785055  0.656
2016 To M, Peterson CW, Roberts MA, Counihan JL, Wu TT, Forster MS, Nomura DK, Olzmann JA. Lipid disequilibrium disrupts ER proteostasis by impairing ERAD substrate glycan trimming and dislocation. Molecular Biology of the Cell. PMID 27881664 DOI: 10.1091/Mbc.E16-07-0483  0.395
2016 Stevenson J, Huang EY, Olzmann JA. Endoplasmic Reticulum-Associated Degradation and Lipid Homeostasis. Annual Review of Nutrition. PMID 27296502 DOI: 10.1146/annurev-nutr-071715-051030  0.382
2013 Olzmann JA, Richter CM, Kopito RR. Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover. Proceedings of the National Academy of Sciences of the United States of America. 110: 1345-50. PMID 23297223 DOI: 10.1073/Pnas.1213738110  0.681
2013 Olzmann JA, Kopito RR, Christianson JC. The mammalian endoplasmic reticulum-associated degradation system. Cold Spring Harbor Perspectives in Biology. 5. PMID 23232094 DOI: 10.1101/Cshperspect.A013185  0.784
2012 Tyler RE, Pearce MM, Shaler TA, Olzmann JA, Greenblatt EJ, Kopito RR. Unassembled CD147 is an endogenous endoplasmic reticulum-associated degradation substrate. Molecular Biology of the Cell. 23: 4668-78. PMID 23097496 DOI: 10.1091/Mbc.E12-06-0428  0.692
2012 Greenblatt EJ, Olzmann JA, Kopito RR. Making the cut: intramembrane cleavage by a rhomboid protease promotes ERAD. Nature Structural & Molecular Biology. 19: 979-81. PMID 23037595 DOI: 10.1038/Nsmb.2398  0.729
2012 Christianson JC, Olzmann JA, Shaler TA, Sowa ME, Bennett EJ, Richter CM, Tyler RE, Greenblatt EJ, Harper JW, Kopito RR. Defining human ERAD networks through an integrative mapping strategy. Nature Cell Biology. 14: 93-105. PMID 22119785 DOI: 10.1038/Ncb2383  0.682
2011 Greenblatt EJ, Olzmann JA, Kopito RR. Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant α-1 antitrypsin from the endoplasmic reticulum. Nature Structural & Molecular Biology. 18: 1147-52. PMID 21909096 DOI: 10.1038/Nsmb.2111  0.724
2011 Lee SM, Olzmann JA, Chin LS, Li L. Mutations associated with Charcot-Marie-Tooth disease cause SIMPLE protein mislocalization and degradation by the proteasome and aggresome-autophagy pathways. Journal of Cell Science. 124: 3319-31. PMID 21896645 DOI: 10.1242/Jcs.087114  0.35
2011 Olzmann JA, Kopito RR. Lipid droplet formation is dispensable for endoplasmic reticulum-associated degradation. The Journal of Biological Chemistry. 286: 27872-4. PMID 21693705 DOI: 10.1074/Jbc.C111.266452  0.698
2009 Wang Y, Pearce MM, Sliter DA, Olzmann JA, Christianson JC, Kopito RR, Boeckmann S, Gagen C, Leichner GS, Roitelman J, Wojcikiewicz RJ. SPFH1 and SPFH2 mediate the ubiquitination and degradation of inositol 1,4,5-trisphosphate receptors in muscarinic receptor-expressing HeLa cells. Biochimica Et Biophysica Acta. 1793: 1710-8. PMID 19751772 DOI: 10.1016/J.Bbamcr.2009.09.004  0.705
2008 Olzmann JA, Chin LS. Parkin-mediated K63-linked polyubiquitination: a signal for targeting misfolded proteins to the aggresome-autophagy pathway. Autophagy. 4: 85-7. PMID 17957134 DOI: 10.4161/Auto.5172  0.323
2007 Kim BY, Olzmann JA, Barsh GS, Chin LS, Li L. Spongiform neurodegeneration-associated E3 ligase Mahogunin ubiquitylates TSG101 and regulates endosomal trafficking. Molecular Biology of the Cell. 18: 1129-42. PMID 17229889 DOI: 10.1091/Mbc.E06-09-0787  0.339
Low-probability matches (unlikely to be authored by this person)
2008 Olzmann JA, Li L, Chin LS. Aggresome formation and neurodegenerative diseases: therapeutic implications. Current Medicinal Chemistry. 15: 47-60. PMID 18220762 DOI: 10.2174/092986708783330692  0.291
2010 Chin LS, Olzmann JA, Li L. Parkin-mediated ubiquitin signalling in aggresome formation and autophagy. Biochemical Society Transactions. 38: 144-9. PMID 20074049 DOI: 10.1042/Bst0380144  0.291
2020 Roberts MA, Segura-Roman A, Olzmann JA. Organelle Biogenesis: ER Shape Influences Lipid Droplet Nucleation. Current Biology : Cb. 30: R770-R773. PMID 32634419 DOI: 10.1016/j.cub.2020.05.027  0.287
2024 Dixon SJ, Olzmann JA. The cell biology of ferroptosis. Nature Reviews. Molecular Cell Biology. PMID 38366038 DOI: 10.1038/s41580-024-00703-5  0.277
2022 Olzmann JA. End of the road: from the ER to the proteasome. Nature Reviews. Molecular Cell Biology. PMID 35672488 DOI: 10.1038/s41580-022-00504-8  0.276
2007 Olzmann JA, Li L, Chudaev MV, Chen J, Perez FA, Palmiter RD, Chin LS. Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6. The Journal of Cell Biology. 178: 1025-38. PMID 17846173 DOI: 10.1083/Jcb.200611128  0.271
2022 Morris SNS, Deol KK, Lange M, Olzmann JA. A genome-wide CRISPR screen implicates plasma membrane asymmetry in exogenous C6-ceramide toxicity. Biology Open. PMID 36409314 DOI: 10.1242/bio.059695  0.27
2019 Spradlin JN, Hu X, Ward CC, Brittain SM, Jones MD, Ou L, To M, Proudfoot A, Ornelas E, Woldegiorgis M, Olzmann JA, Bussiere DE, Thomas JR, Tallarico JA, McKenna JM, et al. Harnessing the anti-cancer natural product nimbolide for targeted protein degradation. Nature Chemical Biology. PMID 31209351 DOI: 10.1038/S41589-019-0304-8  0.27
2019 Bersuker K, Olzmann JA. Identification of Lipid Droplet Proteomes by Proximity Labeling Proteomics Using APEX2. Methods in Molecular Biology (Clifton, N.J.). 2008: 57-72. PMID 31124088 DOI: 10.1007/978-1-4939-9537-0_5  0.264
2017 Nguyen TB, Louie SM, Daniele JR, Tran Q, Dillin A, Zoncu R, Nomura DK, Olzmann JA. DGAT1-Dependent Lipid Droplet Biogenesis Protects Mitochondrial Function during Starvation-Induced Autophagy. Developmental Cell. 42: 9-21.e5. PMID 28697336 DOI: 10.1016/J.Devcel.2017.06.003  0.258
2022 Magtanong L, Mueller GD, Williams KJ, Billmann M, Chan K, Armenta DA, Moffat J, Boone C, Myers CL, Olzmann JA, Bensinger SJ, Dixon SJ. Context-dependent regulation of ferroptosis sensitivity. Cell Chemical Biology. PMID 35809566 DOI: 10.1016/j.chembiol.2022.06.004  0.248
2019 Nguyen TB, Olzmann JA. Getting a handle on lipid droplets: Insights into ER-lipid droplet tethering. The Journal of Cell Biology. PMID 30886057 DOI: 10.1083/jcb.201902160  0.245
2019 Chung CY, Shin HR, Berdan CA, Ford B, Ward CC, Olzmann JA, Zoncu R, Nomura DK. Covalent targeting of the vacuolar H-ATPase activates autophagy via mTORC1 inhibition. Nature Chemical Biology. PMID 31285595 DOI: 10.1038/S41589-019-0308-4  0.229
2004 Olzmann JA, Brown K, Wilkinson KD, Rees HD, Huai Q, Ke H, Levey AI, Li L, Chin LS. Familial Parkinson's disease-associated L166P mutation disrupts DJ-1 protein folding and function. The Journal of Biological Chemistry. 279: 8506-15. PMID 14665635 DOI: 10.1074/Jbc.M311017200  0.228
2018 Olzmann JA, Carvalho P. Dynamics and functions of lipid droplets. Nature Reviews. Molecular Cell Biology. PMID 30523332 DOI: 10.1038/S41580-018-0085-Z  0.205
2017 Nguyen TB, Olzmann JA. Lipid droplets and lipotoxicity during autophagy. Autophagy. 0. PMID 28806138 DOI: 10.1080/15548627.2017.1359451  0.202
2023 Li Z, Lange M, Dixon SJ, Olzmann JA. Lipid Quality Control and Ferroptosis: From Concept to Mechanism. Annual Review of Biochemistry. PMID 37963395 DOI: 10.1146/annurev-biochem-052521-033527  0.197
2023 Rodencal J, Kim N, He A, Li VL, Lange M, He J, Tarangelo A, Schafer ZT, Olzmann JA, Long JZ, Sage J, Dixon SJ. Sensitization of cancer cells to ferroptosis coincident with cell cycle arrest. Cell Chemical Biology. PMID 37963466 DOI: 10.1016/j.chembiol.2023.10.011  0.196
2022 Mejhert N, Gabriel KR, Frendo-Cumbo S, Krahmer N, Song J, Kuruvilla L, Chitraju C, Boland S, Jang DK, von Grotthuss M, Costanzo MC, Rydén M, Olzmann JA, Flannick J, Burtt NP, et al. The Lipid Droplet Knowledge Portal: A resource for systematic analyses of lipid droplet biology. Developmental Cell. 57: 387-397.e4. PMID 35134345 DOI: 10.1016/j.devcel.2022.01.003  0.193
2021 Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... Olzmann JA, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280  0.19
2021 Peterson CWH, Deol KK, To M, Olzmann JA. Optimized protocol for the identification of lipid droplet proteomes using proximity labeling proteomics in cultured human cells. Star Protocols. 2: 100579. PMID 34151299 DOI: 10.1016/j.xpro.2021.100579  0.19
2019 Bersuker K, Hendricks J, Li Z, Magtanong L, Ford B, Tang PH, Roberts MA, Tong B, Maimone TJ, Zoncu R, Bassik MC, Nomura DK, Dixon SJ, Olzmann JA. The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis. Nature. PMID 31634900 DOI: 10.1038/S41586-019-1705-2  0.188
2007 Pridgeon JW, Olzmann JA, Chin LS, Li L. PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1. Plos Biology. 5: e172. PMID 17579517 DOI: 10.1371/Journal.Pbio.0050172  0.173
2023 Rodencal J, Kim N, Li VL, He A, Lange M, He J, Tarangelo A, Schafer ZT, Olzmann JA, Sage J, Long JZ, Dixon SJ. A Cell Cycle-Dependent Ferroptosis Sensitivity Switch Governed by EMP2. Biorxiv : the Preprint Server For Biology. PMID 37502927 DOI: 10.1101/2023.07.19.549715  0.171
2018 Magtanong L, Ko PJ, To M, Cao JY, Forcina GC, Tarangelo A, Ward CC, Cho K, Patti GJ, Nomura DK, Olzmann JA, Dixon SJ. Exogenous Monounsaturated Fatty Acids Promote a Ferroptosis-Resistant Cell State. Cell Chemical Biology. PMID 30686757 DOI: 10.1016/J.Chembiol.2018.11.016  0.171
2009 Kim BY, Olzmann JA, Choi SI, Ahn SY, Kim TI, Cho HS, Suh H, Kim EK. Corneal dystrophy-associated R124H mutation disrupts TGFBI interaction with Periostin and causes mislocalization to the lysosome. The Journal of Biological Chemistry. 284: 19580-91. PMID 19478074 DOI: 10.1074/jbc.M109.013607  0.171
2020 Li Z, Morris SNS, Olzmann JA. Going through a phase. Nature Chemical Biology. 16: 111-112. PMID 31932722 DOI: 10.1038/S41589-019-0448-6  0.169
2017 Anderson KE, To M, Olzmann JA, Nomura DK. Chemoproteomics-Enabled Covalent Ligand Screening Reveals a Thioredoxin-Caspase 3 Interaction Disruptor that Impairs Breast Cancer Pathogenicity. Acs Chemical Biology. PMID 28892616 DOI: 10.1021/Acschembio.7B00711  0.167
2024 Lee N, Park SJ, Lange M, Tseyang T, Doshi MB, Kim TY, Song Y, Kim DI, Greer PL, Olzmann JA, Spinelli JB, Kim D. Selenium reduction of ubiquinone via SQOR suppresses ferroptosis. Nature Metabolism. PMID 38351124 DOI: 10.1038/s42255-024-00974-4  0.163
2023 Hendricks JM, Doubravsky CE, Wehri E, Li Z, Roberts MA, Deol KK, Lange M, Lasheras-Otero I, Momper JD, Dixon SJ, Bersuker K, Schaletzky J, Olzmann JA. Identification of structurally diverse FSP1 inhibitors that sensitize cancer cells to ferroptosis. Cell Chemical Biology. PMID 37178691 DOI: 10.1016/j.chembiol.2023.04.007  0.16
2007 Pridgeon JW, Olzmann JA, Chin L, Li L. PINK1 and TRAP1 Colocalize in the Mitochondrial Inner Membrane and the Intermembrane Space Plos Biology. DOI: 10.1371/Journal.Pbio.0050172.G002  0.154
2015 Riley BE, Olzmann JA. A polyubiquitin chain reaction: parkin recruitment to damaged mitochondria. Plos Genetics. 11: e1004952. PMID 25612006 DOI: 10.1371/Journal.Pgen.1004952  0.151
2022 Li Z, Ferguson L, Deol KK, Roberts MA, Magtanong L, Hendricks JM, Mousa GA, Kilinc S, Schaefer K, Wells JA, Bassik MC, Goga A, Dixon SJ, Ingolia NT, Olzmann JA. Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability. Nature Chemical Biology. PMID 35637349 DOI: 10.1038/s41589-022-01033-3  0.143
2019 Berdan CA, Ho R, Lehtola HS, To M, Hu X, Huffman TR, Petri Y, Altobelli CR, Demeulenaere SG, Olzmann JA, Maimone TJ, Nomura DK. Parthenolide Covalently Targets and Inhibits Focal Adhesion Kinase in Breast Cancer Cells. Cell Chemical Biology. PMID 31080076 DOI: 10.1016/J.Chembiol.2019.03.016  0.137
2017 Bateman LA, Nguyen TB, Roberts AM, Miyamoto DK, Ku WM, Huffman TR, Petri Y, Heslin MJ, Contreras CM, Skibola CF, Olzmann JA, Nomura DK. Chemoproteomics-enabled covalent ligand screen reveals a cysteine hotspot in reticulon 4 that impairs ER morphology and cancer pathogenicity. Chemical Communications (Cambridge, England). PMID 28352901 DOI: 10.1039/C7Cc01480E  0.135
2018 Li Z, Olzmann JA. A Proteomic Map to Navigate Subcellular Reorganization in Fatty Liver Disease. Developmental Cell. 47: 139-141. PMID 30352174 DOI: 10.1016/J.Devcel.2018.10.006  0.132
2004 Vincent AM, Olzmann JA, Brownlee M, Sivitz WI, Russell JW. Uncoupling proteins prevent glucose-induced neuronal oxidative stress and programmed cell death. Diabetes. 53: 726-34. PMID 14988258 DOI: 10.2337/diabetes.53.3.726  0.122
2002 Russell JW, Golovoy D, Vincent AM, Mahendru P, Olzmann JA, Mentzer A, Feldman EL. High glucose-induced oxidative stress and mitochondrial dysfunction in neurons. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 1738-48. PMID 12409316 DOI: 10.1096/Fj.01-1027Com  0.12
2024 Mathiowetz AJ, Olzmann JA. Lipid droplets and cellular lipid flux. Nature Cell Biology. 26: 331-345. PMID 38454048 DOI: 10.1038/s41556-024-01364-4  0.12
2022 Magtanong L, Mueller GD, Williams KJ, Billmann M, Chan K, Armenta DA, Pope LE, Moffat J, Boone C, Myers CL, Olzmann JA, Bensinger SJ, Dixon SJ. Context-dependent regulation of ferroptosis sensitivity. Cell Chemical Biology. 29: 1568. PMID 36270234 DOI: 10.1016/j.chembiol.2022.08.008  0.119
2020 Olzmann J. Lipid Droplet Proteome Dynamics and Lipotoxicity The Faseb Journal. 34: 1-1. DOI: 10.1096/fasebj.2020.34.s1.00200  0.11
2022 Lange M, Olzmann JA. Hydropersulfides are endogenous antioxidants that inhibit ferroptosis. Cell Chemical Biology. 29: 1661-1663. PMID 36525952 DOI: 10.1016/j.chembiol.2022.11.011  0.095
2023 Mathiowetz AJ, Roberts MA, Morgens DW, Olzmann JA, Li Z. Protocol for performing pooled CRISPR-Cas9 loss-of-function screens. Star Protocols. 4: 102201. PMID 37000620 DOI: 10.1016/j.xpro.2023.102201  0.087
2020 Olzmann JA. Diversity through equity and inclusion: The responsibility belongs to all of us. Molecular Biology of the Cell. 31: 2757-2760. PMID 33253074 DOI: 10.1091/mbc.E20-09-0575  0.085
2021 Lange M, Olzmann JA. Ending on a sour note: Lipids orchestrate ferroptosis in cancer. Cell Metabolism. 33: 1507-1509. PMID 34348094 DOI: 10.1016/j.cmet.2021.07.011  0.083
2007 Olzmann JA, Bordelon JR, Muly EC, Rees HD, Levey AI, Li L, Chin LS. Selective enrichment of DJ-1 protein in primate striatal neuronal processes: implications for Parkinson's disease. The Journal of Comparative Neurology. 500: 585-99. PMID 17120294 DOI: 10.1002/Cne.21191  0.083
2021 Olzmann JA, Fendt SM, Shah Y, Vousden K, Chandel N, Horng T, Danial N, Tu B, Christofk H, Vander Heiden MG, Wellen K. More Metabolism! Molecular Cell. 81: 3659-3664. PMID 34547228 DOI: 10.1016/j.molcel.2021.08.040  0.066
2006 Choi J, Sullards MC, Olzmann JA, Rees HD, Weintraub ST, Bostwick DE, Gearing M, Levey AI, Chin LS, Li L. Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases. The Journal of Biological Chemistry. 281: 10816-24. PMID 16517609 DOI: 10.1074/Jbc.M509079200  0.06
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