Yang Shi - Publications

Affiliations: 
Harvard Medical School - Boston Children's Hospital 
Area:
Epigenetics

178 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Karwacki-Neisius V, Jang A, Cukuroglu E, Tai A, Jiao A, Predes D, Yoon J, Brookes E, Chen J, Iberg A, Halbritter F, Õunap K, Gecz J, Schlaeger TM, Ho Sui S, ... ... Shi Y, et al. WNT signalling control by KDM5C during development affects cognition. Nature. PMID 38383780 DOI: 10.1038/s41586-024-07067-y  0.768
2023 Zhang G, Jiang P, Tang W, Wang Y, Qiu F, An J, Zheng Y, Wu D, Zhou J, Neculai D, Shi Y, Sheng W. CPT1A induction following epigenetic perturbation promotes MAVS palmitoylation and activation to potentiate antitumor immunity. Molecular Cell. PMID 38016475 DOI: 10.1016/j.molcel.2023.10.043  0.78
2023 Ng J, Marneth AE, Griffith A, Younger D, Ghanta S, Jiao A, Willis G, Han J, Imani J, Niu B, Keegan JW, Hancock B, Guo F, Shi Y, Perrella MA, et al. Mesenchymal Stromal Cells Facilitate Neutrophil Trained Immunity by Reprogramming Hematopoietic Stem Cells. Journal of Innate Immunity. PMID 37797588 DOI: 10.1159/000533732  0.768
2023 Mu M, Li X, Dong L, Wang J, Cai Q, Hu Y, Wang D, Zhao P, Zhang L, Zhang D, Cheng S, Tan L, Wu F, Shi YG, Xu W, ... Shi Y, et al. METTL14 regulates chromatin bivalent domains in mouse embryonic stem cells. Cell Reports. 42: 112650. PMID 37314930 DOI: 10.1016/j.celrep.2023.112650  0.309
2023 Li L, He Z, Shi Y, Sun H, Yuan B, Cai J, Chen J, Long M. Role of epigenetics in mycotoxin toxicity: a review. Environmental Toxicology and Pharmacology. 104154. PMID 37209890 DOI: 10.1016/j.etap.2023.104154  0.304
2023 Sendinc E, Shi Y. RNA m6A methylation across the transcriptome. Molecular Cell. 83: 428-441. PMID 36736310 DOI: 10.1016/j.molcel.2023.01.006  0.79
2022 Panditharatna E, G Marques J, Wang T, Trissal MC, Liu I, Jiang L, Beck A, Groves A, Dharia NV, Li D, Hoffman SE, Kugener G, Shaw ML, Mire HM, Hack OA, ... ... Shi Y, et al. BAF complex maintains glioma stem cells in pediatric H3K27M-glioma. Cancer Discovery. PMID 36305736 DOI: 10.1158/2159-8290.CD-21-1491  0.754
2022 Zhou C, Huang H, Wang Y, Sendinc E, Shi Y. Selective regulation of tuft cell-like small cell lung cancer by novel transcriptional co-activators C11orf53 and COLCA2. Cell Discovery. 8: 112. PMID 36253350 DOI: 10.1038/s41421-022-00470-7  0.767
2022 Chu Z, Gu L, Hu Y, Zhang X, Li M, Chen J, Teng D, Huang M, Shen CH, Cai L, Yoshida T, Qi Y, Niu Z, Feng A, Geng S, ... ... Shi Y, et al. STAG2 regulates interferon signaling in melanoma via enhancer loop reprogramming. Nature Communications. 13: 1859. PMID 35388001 DOI: 10.1038/s41467-022-29541-9  0.486
2022 Xu W, He C, Kaye EG, Li J, Mu M, Nelson GM, Dong L, Wang J, Wu F, Shi YG, Adelman K, Lan F, Shi Y, Shen H. Dynamic control of chromatin-associated mA methylation regulates nascent RNA synthesis. Molecular Cell. PMID 35219383 DOI: 10.1016/j.molcel.2022.02.006  0.318
2022 Liu Y, Debo B, Li M, Shi Z, Sheng W, Shi Y. Author Correction: LSD1 inhibition sustains T cell invigoration with a durable response to PD-1 blockade. Nature Communications. 13: 263. PMID 34987158 DOI: 10.1038/s41467-021-27814-3  0.752
2021 Liu Y, Debo B, Li M, Shi Z, Sheng W, Shi Y. LSD1 inhibition sustains T cell invigoration with a durable response to PD-1 blockade. Nature Communications. 12: 6831. PMID 34819502 DOI: 10.1038/s41467-021-27179-7  0.776
2021 Blanco MA, Sykes DB, Gu L, Wu M, Petroni R, Karnik R, Wawer M, Rico J, Li H, Jacobus WD, Jambhekar A, Cheloufi S, Meissner A, Hochedlinger K, Scadden DT, ... Shi Y, et al. Chromatin-state barriers enforce an irreversible mammalian cell fate decision. Cell Reports. 37: 109967. PMID 34758323 DOI: 10.1016/j.celrep.2021.109967  0.458
2021 Zee BM, Poels KE, Yao CH, Kawabata KC, Wu G, Duy C, Jacobus WD, Senior E, Endress JE, Jambhekar A, Lovitch SB, Ma J, Dhall A, Harris IS, Blanco MA, ... ... Shi Y, et al. Combined epigenetic and metabolic treatments overcome differentiation blockade in acute myeloid leukemia. Iscience. 24: 102651. PMID 34151238 DOI: 10.1016/j.isci.2021.102651  0.796
2021 Sheng W, Liu Y, Chakraborty D, Debo B, Shi Y. Simultaneous Inhibition of LSD1 and TGF-B Enables Eradication of Poorly Immunogenic Tumors with anti-PD-1 Treatment. Cancer Discovery. PMID 33687985 DOI: 10.1158/2159-8290.CD-20-0017  0.774
2021 Xu W, Li J, He C, Wen J, Ma H, Rong B, Diao J, Wang L, Wang J, Wu F, Tan L, Shi YG, Shi Y, Shen H. METTL3 regulates heterochromatin in mouse embryonic stem cells. Nature. PMID 33505026 DOI: 10.1038/s41586-021-03210-1  0.363
2021 Shi Y, Shi Q, Shen Q, Zhang Q, Cao X. Dicer-independent snRNA/snoRNA-derived nuclear RNA 3 regulates tumor-associated macrophage function by epigenetically repressing inducible nitric oxide synthase transcription. Cancer Communications (London, England). PMID 33455092 DOI: 10.1002/cac2.12131  0.323
2020 Sendinc E, Valle-Garcia D, Jiao A, Shi Y. Analysis of m6A RNA methylation in Caenorhabditis elegans. Cell Discovery. 6: 47. PMID 34257275 DOI: 10.1038/s41421-020-00186-6  0.784
2020 Gu L, Wang L, Chen H, Hong J, Shen Z, Dhall A, Lao T, Liu C, Wang Z, Xu Y, Tang HW, Chakraborty D, Chen J, Liu Z, Rogulja D, ... ... Shi Y, et al. CG14906 (mettl4) mediates mA methylation of U2 snRNA in Drosophila. Cell Discovery. 6: 44. PMID 34188020 DOI: 10.1038/s41421-020-0178-7  0.748
2020 Mikutis S, Gu M, Sendinc E, Hazemi ME, Kiely-Collins H, Aspris D, Vassiliou GS, Shi Y, Tzelepis K, Bernardes GJL. meCLICK-Seq, a Substrate-Hijacking and RNA Degradation Strategy for the Study of RNA Methylation. Acs Central Science. 6: 2196-2208. PMID 33376781 DOI: 10.1021/acscentsci.0c01094  0.775
2020 Cui J, Liu Q, Sendinc E, Shi Y, Gregory RI. Nucleotide resolution profiling of m3C RNA modification by HAC-seq. Nucleic Acids Research. PMID 33313824 DOI: 10.1093/nar/gkaa1186  0.774
2020 Jiao F, Li Z, He C, Xu W, Yang G, Liu T, Shen H, Cai J, Anastas JN, Mao Y, Yu Y, Lan F, Shi YG, Jones C, Xu Y, ... ... Shi Y, et al. RACK7 recognizes H3.3G34R mutation to suppress expression of MHC class II complex components and their delivery pathway in pediatric glioblastoma. Science Advances. 6: eaba2113. PMID 32832624 DOI: 10.1126/Sciadv.Aba2113  0.746
2020 Sendinc E, Valle-Garcia D, Jiao A, Shi Y. Analysis of m6A RNA methylation in . Cell Discovery. 6: 47. PMID 32695436 DOI: 10.1038/S41421-020-00186-6  0.782
2020 Gu L, Wang L, Chen H, Hong J, Shen Z, Dhall A, Lao T, Liu C, Wang Z, Xu Y, Tang HW, Chakraborty D, Chen J, Liu Z, Rogulja D, ... ... Shi Y, et al. CG14906 (mettl4) mediates mA methylation of U2 snRNA in . Cell Discovery. 6: 44. PMID 32637152 DOI: 10.1038/S41421-020-0178-7  0.782
2020 Chen H, Shi Z, Guo J, Chang KJ, Chen Q, Yao CH, Haigis MC, Shi Y. The human mitochondrial 12S rRNA mC methyltransferase METTL15 is required for mitochondrial function. The Journal of Biological Chemistry. PMID 32371392 DOI: 10.1074/Jbc.Ra119.012127  0.769
2020 Li W, Karwacki-Neisius V, Ma C, Tan L, Shi Y, Wu F, Shi YG. Nono deficiency compromises TET1 chromatin association and impedes neuronal differentiation of mouse embryonic stem cells. Nucleic Acids Research. PMID 32286661 DOI: 10.1093/Nar/Gkaa213  0.793
2020 Chen H, Gu L, Orellana EA, Wang Y, Guo J, Liu Q, Wang L, Shen Z, Wu H, Gregory RI, Xing Y, Shi Y. METTL4 is an snRNA mAm methyltransferase that regulates RNA splicing. Cell Research. PMID 31913360 DOI: 10.1038/S41422-019-0270-4  0.527
2019 Jambhekar A, Dhall A, Shi Y. Author Correction: Roles and regulation of histone methylation in animal development. Nature Reviews. Molecular Cell Biology. PMID 31700131 DOI: 10.1038/S41580-019-0192-5  0.755
2019 Anastas JN, Zee BM, Kalin JH, Kim M, Guo R, Alexandrescu S, Blanco MA, Giera S, Gillespie SM, Das J, Wu M, Nocco S, Bonal DM, Nguyen QD, Suva ML, ... ... Shi Y, et al. Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG. Cancer Cell. PMID 31631026 DOI: 10.1016/J.Ccell.2019.09.005  0.802
2019 Sendinc E, Valle-Garcia D, Dhall A, Chen H, Henriques T, Navarrete-Perea J, Sheng W, Gygi SP, Adelman K, Shi Y. PCIF1 Catalyzes m6Am mRNA Methylation to Regulate Gene Expression. Molecular Cell. PMID 31279659 DOI: 10.1016/J.Molcel.2019.05.030  0.773
2019 Jambhekar A, Dhall A, Shi Y. Roles and regulation of histone methylation in animal development. Nature Reviews. Molecular Cell Biology. PMID 31267065 DOI: 10.1038/S41580-019-0151-1  0.778
2019 Zhang J, Lee YR, Dang F, Gan W, Menon AV, Katon JM, Hsu CH, Asara JM, Tibarewal P, Leslie NR, Shi Y, Pandolfi PP, Wei W. PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage. Cancer Discovery. PMID 31217297 DOI: 10.1158/2159-8290.Cd-18-0083  0.589
2019 O'Brown ZK, Boulias K, Wang J, Wang SY, O'Brown NM, Hao Z, Shibuya H, Fady PE, Shi Y, He C, Megason SG, Liu T, Greer EL. Sources of artifact in measurements of 6mA and 4mC abundance in eukaryotic genomic DNA. Bmc Genomics. 20: 445. PMID 31159718 DOI: 10.1186/S12864-019-5754-6  0.323
2019 Anastas JN, Shi Y. Histone Serotonylation: Can the Brain Have "Happy" Chromatin? Molecular Cell. 74: 418-420. PMID 31051139 DOI: 10.1016/J.Molcel.2019.04.017  0.752
2019 Guo J, Dai X, Laurent B, Zheng N, Gan W, Zhang J, Guo A, Yuan M, Liu P, Asara JM, Toker A, Shi Y, Pandolfi PP, Wei W. AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions. Nature Cell Biology. PMID 30692625 DOI: 10.1038/S41556-018-0261-6  0.355
2019 Byrum AK, Carvajal-Maldonado D, Mudge MC, Valle-Garcia D, Majid MC, Patel R, Sowa ME, Gygi SP, Harper JW, Shi Y, Vindigni A, Mosammaparast N. Mitotic regulators TPX2 and Aurora A protect DNA forks during replication stress by counteracting 53BP1 function. The Journal of Cell Biology. PMID 30602538 DOI: 10.1083/Jcb.201803003  0.317
2019 Ma H, Wang X, Cai J, Dai Q, Natchiar SK, Lv R, Chen K, Lu Z, Chen H, Shi YG, Lan F, Fan J, Klaholz BP, Pan T, Shi Y, et al. NMethyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation. Nature Chemical Biology. 15: 88-94. PMID 30531910 DOI: 10.1038/S41589-018-0184-3  0.385
2018 Sheng W, LaFleur MW, Nguyen TH, Chen S, Chakravarthy A, Conway JR, Li Y, Chen H, Yang H, Hsu PH, Van Allen EM, Freeman GJ, De Carvalho DD, He HH, Sharpe AH, ... Shi Y, et al. LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade. Cell. PMID 29937226 DOI: 10.1016/J.Cell.2018.05.052  0.788
2018 Wen J, Lv R, Ma H, Shen H, He C, Wang J, Jiao F, Liu H, Yang P, Tan L, Lan F, Shi YG, He C, Shi Y, Diao J. Zc3h13 Regulates Nuclear RNA mA Methylation and Mouse Embryonic Stem Cell Self-Renewal. Molecular Cell. 69: 1028-1038.e6. PMID 29547716 DOI: 10.1016/J.Molcel.2018.02.015  0.416
2018 Jha D, Daley GQ, Laurent B, Zhang C, Kubaczka C, Chapuy B, Sousa P, Missios P, Rowe RG, Huang Y, Tan Y, Barragan J, North T, Schlaeger T, Li H, ... Shi Y, et al. Novel Epigenetic Vulnerabilities for Diffuse Large B-Cell Lymphoma Blood. 132: 2600-2600. DOI: 10.1182/Blood-2018-99-115030  0.404
2018 Anastas J, Filbin M, Kim M, Kalin J, Zee B, Blanco A, Das J, Golub T, Cole P, Shi Y. Gene-22. Re-Programing Chromatin With A Bifunctional Lsd1/Hdac Inhibitor Induces Therapeutic Differentiation In Dipg Neuro-Oncology. 20. DOI: 10.1093/Neuonc/Noy148.448  0.331
2017 Xiang Y, Laurent B, Hsu CH, Nachtergaele S, Lu Z, Sheng W, Xu C, Chen H, Ouyang J, Wang S, Ling D, Hsu PH, Zou L, Jambhekar A, He C, ... Shi Y, et al. Corrigendum: RNA m6A methylation regulates the ultraviolet-induced DNA damage response. Nature. PMID 29186122 DOI: 10.1038/Nature24007  0.796
2017 Tan L, Ke Z, Tombline G, Macoretta N, Hayes K, Tian X, Lv R, Ablaeva J, Gilbert M, Bhanu NV, Yuan ZF, Garcia BA, Shi YG, Shi Y, Seluanov A, et al. Naked Mole Rat Cells Have a Stable Epigenome that Resists iPSC Reprogramming. Stem Cell Reports. PMID 29107597 DOI: 10.1016/J.Stemcr.2017.10.001  0.513
2017 Scandaglia M, Lopez-Atalaya JP, Medrano-Fernandez A, Lopez-Cascales MT, Del Blanco B, Lipinski M, Benito E, Olivares R, Iwase S, Shi Y, Barco A. Loss of Kdm5c Causes Spurious Transcription and Prevents the Fine-Tuning of Activity-Regulated Enhancers in Neurons. Cell Reports. 21: 47-59. PMID 28978483 DOI: 10.1016/J.Celrep.2017.09.014  0.355
2017 Li H, Liefke R, Jiang J, Kurland JV, Tian W, Deng P, Zhang W, He Q, Patel DJ, Bulyk ML, Shi Y, Wang Z. Polycomb-like proteins link the PRC2 complex to CpG islands. Nature. PMID 28869966 DOI: 10.1038/Nature23881  0.406
2017 Murn J, Shi Y. The winding path of protein methylation research: milestones and new frontiers. Nature Reviews. Molecular Cell Biology. PMID 28512349 DOI: 10.1038/Nrm.2017.35  0.352
2017 Xiang Y, Laurent B, Hsu CH, Nachtergaele S, Lu Z, Sheng W, Xu C, Chen H, Ouyang J, Wang S, Ling D, Hsu PH, Zou L, Jambhekar A, He C, ... Shi Y, et al. RNA m(6)A methylation regulates the ultraviolet-induced DNA damage response. Nature. PMID 28297716 DOI: 10.1038/Nature21671  0.78
2017 Liefke R, Karwacki-Neisius V, Shi Y. EPOP Interacts with Elongin BC and USP7 to Modulate the Chromatin Landscape. Molecular Cell. 65: 202. PMID 28061330 DOI: 10.1016/J.Molcel.2016.12.006  0.769
2017 Jambhekar A, Anastas JN, Shi Y. Histone Lysine Demethylase Inhibitors. Cold Spring Harbor Perspectives in Medicine. 7. PMID 28049654 DOI: 10.1101/Cshperspect.A026484  0.763
2016 Liefke R, Karwacki-Neisius V, Shi Y. EPOP Interacts with Elongin BC and USP7 to Modulate the Chromatin Landscape. Molecular Cell. 64: 659-672. PMID 27863226 DOI: 10.1016/J.Molcel.2016.10.019  0.8
2016 Ma C, Karwacki-Neisius V, Tang H, Li W, Shi Z, Hu H, Xu W, Wang Z, Kong L, Lv R, Fan Z, Zhou W, Yang P, Wu F, Diao J, ... Shi YG, ... Shi Y, et al. Nono, a Bivalent Domain Factor, Regulates Erk Signaling and Mouse Embryonic Stem Cell Pluripotency. Cell Reports. 17: 997-1007. PMID 27760330 DOI: 10.1016/J.Celrep.2016.09.078  0.791
2016 Aranda S, Shi Y, Di Croce L. Chromatin and epigenetics at the forefront: finding clues among peaks. Molecular and Cellular Biology. PMID 27402863 DOI: 10.1128/Mcb.00328-16  0.346
2016 Kong L, Tan L, Lv R, Shi Z, Xiong L, Wu F, Rabidou K, Smith M, He C, Zhang L, Qian Y, Ma D, Lan F, Shi Y, Shi YG. A primary role of TET proteins in establishment and maintenance of De Novo bivalency at CpG islands. Nucleic Acids Research. PMID 27288448 DOI: 10.1093/Nar/Gkw529  0.787
2016 Shen H, Xu W, Guo R, Rong B, Gu L, Wang Z, He C, Zheng L, Hu X, Hu Z, Shao ZM, Yang P, Wu F, Shi YG, Shi Y, et al. Suppression of Enhancer Overactivation by a RACK7-Histone Demethylase Complex. Cell. 165: 331-342. PMID 27058665 DOI: 10.1016/J.Cell.2016.02.064  0.513
2016 Iwase S, Brookes E, Agarwal S, Badeaux AI, Ito H, Vallianatos CN, Tomassy GS, Kasza T, Lin G, Thompson A, Gu L, Kwan KY, Chen C, Sartor MA, Egan B, ... Shi Y, et al. A Mouse Model of X-linked Intellectual Disability Associated with Impaired Removal of Histone Methylation. Cell Reports. PMID 26804915 DOI: 10.1016/J.Celrep.2015.12.091  0.55
2015 Liefke R, Shi Y. The PRC2-associated factor C17orf96 is a novel CpG island regulator in mouse ES cells. Cell Discovery. 1: 15008. PMID 27462409 DOI: 10.1038/Celldisc.2015.8  0.463
2015 Greer EL, Becker B, Latza C, Antebi A, Shi Y. Mutation of C. elegans demethylase spr-5 extends transgenerational longevity. Cell Research. PMID 26691751 DOI: 10.1038/Cr.2015.148  0.348
2015 Cheloufi S, Elling U, Hopfgartner B, Jung YL, Murn J, Ninova M, Hubmann M, Badeaux AI, Euong Ang C, Tenen D, Wesche DJ, Abazova N, Hogue M, Tasdemir N, Brumbaugh J, ... ... Shi Y, et al. The histone chaperone CAF-1 safeguards somatic cell identity. Nature. 528: 218-224. PMID 26659182 DOI: 10.1038/Nature15749  0.432
2015 Murn J, Teplova M, Zarnack K, Shi Y, Patel DJ. Recognition of distinct RNA motifs by the clustered CCCH zinc fingers of neuronal protein Unkempt. Nature Structural & Molecular Biology. PMID 26641712 DOI: 10.1038/Nsmb.3140  0.319
2015 Luo GZ, Blanco MA, Greer EL, He C, Shi Y. DNA N(6)-methyladenine: a new epigenetic mark in eukaryotes? Nature Reviews. Molecular Cell Biology. PMID 26507168 DOI: 10.1038/Nrm4076  0.373
2015 Chen M, Zhu N, Liu X, Laurent B, Tang Z, Eng R, Shi Y, Armstrong SA, Roeder RG. JMJD1C is required for the survival of acute myeloid leukemia by functioning as a coactivator for key transcription factors. Genes & Development. 29: 2123-39. PMID 26494788 DOI: 10.1101/Gad.267278.115  0.362
2015 van Oevelen C, Collombet S, Vicent G, Hoogenkamp M, Lepoivre C, Badeaux A, Bussmann L, Sardina JL, Thieffry D, Beato M, Shi Y, Bonifer C, Graf T. C/EBPα Activates Pre-existing and De Novo Macrophage Enhancers during Induced Pre-B Cell Transdifferentiation and Myelopoiesis. Stem Cell Reports. PMID 26235892 DOI: 10.1016/J.Stemcr.2015.06.007  0.309
2015 Sendinc E, Jambhekar A, Shi Y. Remodeling Your Way out of Cell Cycle. Cell. 162: 237-8. PMID 26186182 DOI: 10.1016/J.Cell.2015.06.050  0.781
2015 Greer EL, Blanco MA, Gu L, Sendinc E, Liu J, Aristizábal-Corrales D, Hsu CH, Aravind L, He C, Shi Y. DNA Methylation on N(6)-Adenine in C. elegans. Cell. 161: 868-78. PMID 25936839 DOI: 10.1016/J.Cell.2015.04.005  0.792
2015 Murn J, Zarnack K, Yang YJ, Durak O, Murphy EA, Cheloufi S, Gonzalez DM, Teplova M, Curk T, Zuber J, Patel DJ, Ule J, Luscombe NM, Tsai LH, Walsh CA, ... Shi Y, et al. Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt. Genes & Development. 29: 501-12. PMID 25737280 DOI: 10.1101/Gad.258483.115  0.331
2015 Laurent B, Ruitu L, Murn J, Hempel K, Ferrao R, Xiang Y, Liu S, Garcia BA, Wu H, Wu F, Steen H, Shi Y. A specific LSD1/KDM1A isoform regulates neuronal differentiation through H3K9 demethylation. Molecular Cell. 57: 957-70. PMID 25684206 DOI: 10.1016/J.Molcel.2015.01.010  0.485
2015 Brookes E, Laurent B, Õunap K, Carroll R, Moeschler JB, Field M, Schwartz CE, Gecz J, Shi Y. Mutations in the intellectual disability gene KDM5C reduce protein stability and demethylase activity. Human Molecular Genetics. 24: 2861-72. PMID 25666439 DOI: 10.1093/Hmg/Ddv046  0.31
2015 Lan F, Shi Y. Histone H3.3 and cancer: A potential reader connection. Proceedings of the National Academy of Sciences of the United States of America. 112: 6814-9. PMID 25453099 DOI: 10.1073/Pnas.1418996111  0.315
2014 Guo R, Zheng L, Park JW, Lv R, Chen H, Jiao F, Xu W, Mu S, Wen H, Qiu J, Wang Z, Yang P, Wu F, Hui J, Fu X, ... ... Shi YG, ... ... Shi Y, et al. BS69/ZMYND11 reads and connects histone H3.3 lysine 36 trimethylation-decorated chromatin to regulated pre-mRNA processing. Molecular Cell. 56: 298-310. PMID 25263594 DOI: 10.1016/J.Molcel.2014.08.022  0.409
2014 Brookes E, Shi Y. Diverse epigenetic mechanisms of human disease. Annual Review of Genetics. 48: 237-268. PMID 25195505 DOI: 10.1146/Annurev-Genet-120213-092518  0.321
2014 Tsai CL, Shi Y, Tainer JA. How substrate specificity is imposed on a histone demethylase--lessons from KDM2A. Genes & Development. 28: 1735-8. PMID 25128493 DOI: 10.1101/Gad.249755.114  0.401
2014 Alpatov R, Lesch BJ, Nakamoto-Kinoshita M, Blanco A, Chen S, Stützer A, Armache KJ, Simon MD, Xu C, Ali M, Murn J, Prisic S, Kutateladze TG, Vakoc CR, Min J, ... ... Shi Y, et al. A chromatin-dependent role of the fragile X mental retardation protein FMRP in the DNA damage response. Cell. 157: 869-81. PMID 24813610 DOI: 10.1016/J.Cell.2014.03.040  0.343
2014 Greer EL, Beese-Sims SE, Brookes E, Spadafora R, Zhu Y, Rothbart SB, Aristizábal-Corrales D, Chen S, Badeaux AI, Jin Q, Wang W, Strahl BD, Colaiácovo MP, Shi Y. A histone methylation network regulates transgenerational epigenetic memory in C. elegans. Cell Reports. 7: 113-26. PMID 24685137 DOI: 10.1016/J.Celrep.2014.02.044  0.397
2013 Mosammaparast N, Kim H, Laurent B, Zhao Y, Lim HJ, Majid MC, Dango S, Luo Y, Hempel K, Sowa ME, Gygi SP, Steen H, Harper JW, Yankner B, Shi Y. The histone demethylase LSD1/KDM1A promotes the DNA damage response. The Journal of Cell Biology. 203: 457-70. PMID 24217620 DOI: 10.1083/Jcb.201302092  0.364
2013 Lim HJ, Dimova NV, Tan MK, Sigoillot FD, King RW, Shi Y. The G2/M regulator histone demethylase PHF8 is targeted for degradation by the anaphase-promoting complex containing CDC20. Molecular and Cellular Biology. 33: 4166-80. PMID 23979597 DOI: 10.1128/Mcb.00689-13  0.355
2013 Pan X, Papasani M, Hao Y, Calamito M, Wei F, Quinn Iii WJ, Basu A, Wang J, Hodawadekar S, Zaprazna K, Liu H, Shi Y, Allman D, Cancro M, Atchison ML. YY1 controls Igκ repertoire and B-cell development, and localizes with condensin on the Igκ locus. The Embo Journal. 32: 1168-82. PMID 23531880 DOI: 10.1038/Emboj.2013.66  0.302
2013 Badeaux AI, Shi Y. Emerging roles for chromatin as a signal integration and storage platform. Nature Reviews. Molecular Cell Biology. 14: 211-24. PMID 23524488 DOI: 10.1038/Nrm3545  0.369
2013 Chen H, Ma H, Inuzuka H, Diao J, Lan F, Shi YG, Wei W, Shi Y. DNA damage regulates UHRF1 stability via the SCF(β-TrCP) E3 ligase. Molecular and Cellular Biology. 33: 1139-48. PMID 23297342 DOI: 10.1128/Mcb.01191-12  0.32
2012 Yang YJ, Baltus AE, Mathew RS, Murphy EA, Evrony GD, Gonzalez DM, Wang EP, Marshall-Walker CA, Barry BJ, Murn J, Tatarakis A, Mahajan MA, Samuels HH, Shi Y, Golden JA, et al. Microcephaly gene links trithorax and REST/NRSF to control neural stem cell proliferation and differentiation. Cell. 151: 1097-112. PMID 23178126 DOI: 10.1016/J.Cell.2012.10.043  0.381
2012 Ballaré C, Lange M, Lapinaite A, Martin GM, Morey L, Pascual G, Liefke R, Simon B, Shi Y, Gozani O, Carlomagno T, Benitah SA, Di Croce L. Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity. Nature Structural & Molecular Biology. 19: 1257-65. PMID 23104054 DOI: 10.1038/Nsmb.2434  0.426
2012 Chen S, Shi Y. A new horizon for epigenetic medicine? Cell Research. 23: 326-8. PMID 22986503 DOI: 10.1038/Cr.2012.136  0.39
2012 Kim HG, Kim HT, Leach NT, Lan F, Ullmann R, Silahtaroglu A, Kurth I, Nowka A, Seong IS, Shen Y, Talkowski ME, Ruderfer D, Lee JH, Glotzbach C, Ha K, ... ... Shi Y, et al. Translocations disrupting PHF21A in the Potocki-Shaffer-syndrome region are associated with intellectual disability and craniofacial anomalies. American Journal of Human Genetics. 91: 56-72. PMID 22770980 DOI: 10.1016/J.Ajhg.2012.05.005  0.36
2012 Chen S, Ma J, Wu F, Xiong LJ, Ma H, Xu W, Lv R, Li X, Villen J, Gygi SP, Liu XS, Shi Y. The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation. Genes & Development. 26: 1364-75. PMID 22713873 DOI: 10.1101/Gad.186056.111  0.418
2012 Greer EL, Shi Y. Histone methylation: a dynamic mark in health, disease and inheritance. Nature Reviews. Genetics. 13: 343-57. PMID 22473383 DOI: 10.1038/Nrg3173  0.412
2012 Ma H, Chen H, Guo X, Wang Z, Sowa ME, Zheng L, Hu S, Zeng P, Guo R, Diao J, Lan F, Harper JW, Shi YG, Xu Y, Shi Y. M phase phosphorylation of the epigenetic regulator UHRF1 regulates its physical association with the deubiquitylase USP7 and stability. Proceedings of the National Academy of Sciences of the United States of America. 109: 4828-33. PMID 22411829 DOI: 10.1073/Pnas.1116349109  0.352
2012 Wang Y, Kallgren SP, Reddy BD, Kuntz K, López-Maury L, Thompson J, Watt S, Ma C, Hou H, Shi Y, Yates JR, Bähler J, O'Connell MJ, Jia S. Histone H3 lysine 14 acetylation is required for activation of a DNA damage checkpoint in fission yeast. The Journal of Biological Chemistry. 287: 4386-93. PMID 22184112 DOI: 10.1074/Jbc.M111.329417  0.397
2011 Dango S, Mosammaparast N, Sowa ME, Xiong LJ, Wu F, Park K, Rubin M, Gygi S, Harper JW, Shi Y. DNA unwinding by ASCC3 helicase is coupled to ALKBH3-dependent DNA alkylation repair and cancer cell proliferation. Molecular Cell. 44: 373-84. PMID 22055184 DOI: 10.1016/J.Molcel.2011.08.039  0.326
2011 Greer EL, Maures TJ, Ucar D, Hauswirth AG, Mancini E, Lim JP, Benayoun BA, Shi Y, Brunet A. Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans. Nature. 479: 365-71. PMID 22012258 DOI: 10.1038/Nature10572  0.38
2011 Rajakumara E, Wang Z, Ma H, Hu L, Chen H, Lin Y, Guo R, Wu F, Li H, Lan F, Shi YG, Xu Y, Patel DJ, Shi Y. PHD finger recognition of unmodified histone H3R2 links UHRF1 to regulation of euchromatic gene expression. Molecular Cell. 43: 275-84. PMID 21777816 DOI: 10.1016/J.Molcel.2011.07.006  0.422
2011 Nottke AC, Beese-Sims SE, Pantalena LF, Reinke V, Shi Y, Colaiácovo MP. SPR-5 is a histone H3K4 demethylase with a role in meiotic double-strand break repair. Proceedings of the National Academy of Sciences of the United States of America. 108: 12805-10. PMID 21768382 DOI: 10.1073/Pnas.1102298108  0.429
2011 Iwase S, Xiang B, Ghosh S, Ren T, Lewis PW, Cochrane JC, Allis CD, Picketts DJ, Patel DJ, Li H, Shi Y. ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome. Nature Structural & Molecular Biology. 18: 769-76. PMID 21666679 DOI: 10.1038/Nsmb.2062  0.321
2011 Rahman S, Sowa ME, Ottinger M, Smith JA, Shi Y, Harper JW, Howley PM. The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3. Molecular and Cellular Biology. 31: 2641-52. PMID 21555454 DOI: 10.1128/Mcb.01341-10  0.378
2011 Iwase S, Shi Y. Histone and DNA modifications in mental retardation. Progress in Drug Research. Fortschritte Der Arzneimittelforschung. Progres Des Recherches Pharmaceutiques. 67: 147-73. PMID 21141729 DOI: 10.1007/978-3-7643-8989-5_8  0.356
2010 Yu H, Mashtalir N, Daou S, Hammond-Martel I, Ross J, Sui G, Hart GW, Rauscher FJ, Drobetsky E, Milot E, Shi Y, Affar el B. The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression. Molecular and Cellular Biology. 30: 5071-85. PMID 20805357 DOI: 10.1128/Mcb.00396-10  0.391
2010 Fang R, Barbera AJ, Xu Y, Rutenberg M, Leonor T, Bi Q, Lan F, Mei P, Yuan GC, Lian C, Peng J, Cheng D, Sui G, Kaiser UB, Shi Y, ... Shi YG, et al. Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation. Molecular Cell. 39: 222-33. PMID 20670891 DOI: 10.1016/J.Molcel.2010.07.008  0.436
2010 Qi HH, Sarkissian M, Hu GQ, Wang Z, Bhattacharjee A, Gordon DB, Gonzales M, Lan F, Ongusaha PP, Huarte M, Yaghi NK, Lim H, Garcia BA, Brizuela L, Zhao K, ... ... Shi Y, et al. Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development. Nature. 466: 503-7. PMID 20622853 DOI: 10.1038/Nature09261  0.569
2010 Tsai MC, Manor O, Wan Y, Mosammaparast N, Wang JK, Lan F, Shi Y, Segal E, Chang HY. Long noncoding RNA as modular scaffold of histone modification complexes. Science (New York, N.Y.). 329: 689-93. PMID 20616235 DOI: 10.1126/Science.1192002  0.406
2010 Mosammaparast N, Shi Y. Reversal of histone methylation: biochemical and molecular mechanisms of histone demethylases. Annual Review of Biochemistry. 79: 155-79. PMID 20373914 DOI: 10.1146/Annurev.Biochem.78.070907.103946  0.395
2010 Honda S, Lewis ZA, Huarte M, Cho LY, David LL, Shi Y, Selker EU. The DMM complex prevents spreading of DNA methylation from transposons to nearby genes in Neurospora crassa. Genes & Development. 24: 443-54. PMID 20139222 DOI: 10.1101/Gad.1893210  0.373
2010 Wang JK, Tsai MC, Poulin G, Adler AS, Chen S, Liu H, Shi Y, Chang HY. The histone demethylase UTX enables RB-dependent cell fate control. Genes & Development. 24: 327-32. PMID 20123895 DOI: 10.1101/Gad.1882610  0.423
2010 Horton JR, Upadhyay AK, Qi HH, Zhang X, Shi Y, Cheng X. Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases. Nature Structural & Molecular Biology. 17: 38-43. PMID 20023638 DOI: 10.1038/Nsmb.1753  0.361
2009 Wang B, Li S, Qi HH, Chowdhury D, Shi Y, Novina CD. Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins. Nature Structural & Molecular Biology. 16: 1259-66. PMID 19946268 DOI: 10.1038/Nsmb.1712  0.323
2009 Falbo KB, Alabert C, Katou Y, Wu S, Han J, Wehr T, Xiao J, He X, Zhang Z, Shi Y, Shirahige K, Pasero P, Shen X. Involvement of a chromatin remodeling complex in damage tolerance during DNA replication. Nature Structural & Molecular Biology. 16: 1167-72. PMID 19855395 DOI: 10.1038/Nsmb.1686  0.335
2009 Wu S, Hu YC, Liu H, Shi Y. Loss of YY1 impacts the heterochromatic state and meiotic double-strand breaks during mouse spermatogenesis. Molecular and Cellular Biology. 29: 6245-56. PMID 19786570 DOI: 10.1128/Mcb.00679-09  0.383
2009 Lan F, Shi Y. Epigenetic regulation: methylation of histone and non-histone proteins. Science in China. Series C, Life Sciences. 52: 311-22. PMID 19381457 DOI: 10.1007/S11427-009-0054-Z  0.408
2009 Nottke A, Colaiácovo MP, Shi Y. Developmental roles of the histone lysine demethylases. Development (Cambridge, England). 136: 879-89. PMID 19234061 DOI: 10.1242/Dev.020966  0.386
2009 Chen S, Whetstine JR, Ghosh S, Hanover JA, Gali RR, Grosu P, Shi Y. The conserved NAD(H)-dependent corepressor CTBP-1 regulates Caenorhabditis elegans life span. Proceedings of the National Academy of Sciences of the United States of America. 106: 1496-501. PMID 19164523 DOI: 10.1073/Pnas.0802674106  0.362
2008 Mulligan P, Westbrook TF, Ottinger M, Pavlova N, Chang B, Macia E, Shi YJ, Barretina J, Liu J, Howley PM, Elledge SJ, Shi Y. CDYL Bridges REST and Histone Methyltransferases for Gene Repression and Suppression of Cellular Transformation Molecular Cell. 32: 718-726. PMID 19061646 DOI: 10.1016/J.Molcel.2008.10.025  0.371
2008 Li F, Huarte M, Zaratiegui M, Vaughn MW, Shi Y, Martienssen R, Cande WZ. Lid2 is required for coordinating H3K4 and H3K9 methylation of heterochromatin and euchromatin. Cell. 135: 272-83. PMID 18957202 DOI: 10.1016/J.Cell.2008.08.036  0.428
2008 Qi HH, Ongusaha PP, Myllyharju J, Cheng D, Pakkanen O, Shi Y, Lee SW, Peng J, Shi Y. Prolyl 4-hydroxylation regulates Argonaute 2 stability. Nature. 455: 421-4. PMID 18690212 DOI: 10.1038/Nature07186  0.338
2008 Tsai WW, Nguyen TT, Shi Y, Barton MC. p53-targeted LSD1 functions in repression of chromatin structure and transcription in vivo. Molecular and Cellular Biology. 28: 5139-46. PMID 18573881 DOI: 10.1128/Mcb.00287-08  0.342
2008 Lan F, Nottke AC, Shi Y. Mechanisms involved in the regulation of histone lysine demethylases. Current Opinion in Cell Biology. 20: 316-25. PMID 18440794 DOI: 10.1016/J.Ceb.2008.03.004  0.394
2007 Matthews AG, Kuo AJ, Ramón-Maiques S, Han S, Champagne KS, Ivanov D, Gallardo M, Carney D, Cheung P, Ciccone DN, Walter KL, Utz PJ, Shi Y, Kutateladze TG, Yang W, et al. RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination. Nature. 450: 1106-10. PMID 18033247 DOI: 10.1038/Nature06431  0.395
2007 Wu S, Shi Y, Mulligan P, Gay F, Landry J, Liu H, Lu J, Qi HH, Wang W, Nickoloff JA, Wu C, Shi Y. A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair. Nature Structural & Molecular Biology. 14: 1165-72. PMID 18026119 DOI: 10.1038/Nsmb1332  0.344
2007 Shi Y. Histone lysine demethylases: Emerging roles in development, physiology and disease Nature Reviews Genetics. 8: 829-833. PMID 17909537 DOI: 10.1038/Nrg2218  0.397
2007 Lan F, Bayliss PE, Rinn JL, Whetstine JR, Wang JK, Chen S, Iwase S, Alpatov R, Issaeva I, Canaani E, Roberts TM, Chang HY, Shi Y. A histone H3 lysine 27 demethylase regulates animal posterior development. Nature. 449: 689-94. PMID 17851529 DOI: 10.1038/Nature06192  0.445
2007 Cai Y, Jin J, Yao T, Gottschalk AJ, Swanson SK, Wu S, Shi Y, Washburn MP, Florens L, Conaway RC, Conaway JW. YY1 functions with INO80 to activate transcription. Nature Structural & Molecular Biology. 14: 872-4. PMID 17721549 DOI: 10.1038/Nsmb1276  0.368
2007 Lan F, Collins RE, De Cegli R, Alpatov R, Horton JR, Shi X, Gozani O, Cheng X, Shi Y. Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression. Nature. 448: 718-22. PMID 17687328 DOI: 10.1038/Nature06034  0.433
2007 Chen Z, Zang J, Kappler J, Hong X, Crawford F, Wang Q, Lan F, Jiang C, Whetstine J, Dai S, Hansen K, Shi Y, Zhang G. Structural basis of the recognition of a methylated histone tail by JMJD2A. Proceedings of the National Academy of Sciences of the United States of America. 104: 10818-23. PMID 17567753 DOI: 10.1073/Pnas.0704525104  0.349
2007 Huarte M, Lan F, Kim T, Vaughn MW, Zaratiegui M, Martienssen RA, Buratowski S, Shi Y. The fission yeast Jmj2 reverses histone H3 Lysine 4 trimethylation. The Journal of Biological Chemistry. 282: 21662-70. PMID 17550896 DOI: 10.1074/Jbc.M703897200  0.401
2007 Lan F, Zaratiegui M, Villén J, Vaughn MW, Verdel A, Huarte M, Shi Y, Gygi SP, Moazed D, Martienssen RA, Shi Y. S. pombe LSD1 homologs regulate heterochromatin propagation and euchromatic gene transcription. Molecular Cell. 26: 89-101. PMID 17434129 DOI: 10.1016/J.Molcel.2007.02.023  0.426
2007 Horwitz AA, Affar el B, Heine GF, Shi Y, Parvin JD. A mechanism for transcriptional repression dependent on the BRCA1 E3 ubiquitin ligase. Proceedings of the National Academy of Sciences of the United States of America. 104: 6614-9. PMID 17420471 DOI: 10.1073/Pnas.0610481104  0.375
2007 Iwase S, Lan F, Bayliss P, de la Torre-Ubieta L, Huarte M, Qi HH, Whetstine JR, Bonni A, Roberts TM, Shi Y. The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases. Cell. 128: 1077-88. PMID 17320160 DOI: 10.1016/J.Cell.2007.02.017  0.398
2007 Shi Y, Whetstine JR. Dynamic regulation of histone lysine methylation by demethylases. Molecular Cell. 25: 1-14. PMID 17218267 DOI: 10.1016/J.Molcel.2006.12.010  0.399
2007 Shi Y. Taking Epigenetics Center Stage Cell. 128: 639-640. DOI: 10.1016/J.Cell.2007.02.011  0.419
2006 Luke MP, Sui G, Liu H, Shi Y. Yin Yang 1 physically interacts with Hoxa11 and represses Hoxa11-dependent transcription. The Journal of Biological Chemistry. 281: 33226-32. PMID 16963455 DOI: 10.1074/Jbc.M606584200  0.366
2006 Shi X, Hong T, Walter KL, Ewalt M, Michishita E, Hung T, Carney D, Peña P, Lan F, Kaadige MR, Lacoste N, Cayrou C, Davrazou F, Saha A, Cairns BR, ... ... Shi Y, et al. ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression. Nature. 442: 96-9. PMID 16728974 DOI: 10.1038/Nature04835  0.432
2006 Chen Z, Zang J, Whetstine J, Hong X, Davrazou F, Kutateladze TG, Simpson M, Mao Q, Pan CH, Dai S, Hagman J, Hansen K, Shi Y, Zhang G. Structural insights into histone demethylation by JMJD2 family members. Cell. 125: 691-702. PMID 16677698 DOI: 10.1016/J.Cell.2006.04.024  0.361
2006 Affar el B, Gay F, Shi Y, Liu H, Huarte M, Wu S, Collins T, Li E, Shi Y. Essential dosage-dependent functions of the transcription factor yin yang 1 in late embryonic development and cell cycle progression. Molecular and Cellular Biology. 26: 3565-81. PMID 16611997 DOI: 10.1128/Mcb.26.9.3565-3581.2006  0.385
2006 Whetstine JR, Nottke A, Lan F, Huarte M, Smolikov S, Chen Z, Spooner E, Li E, Zhang G, Colaiacovo M, Shi Y. Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases. Cell. 125: 467-81. PMID 16603238 DOI: 10.1016/J.Cell.2006.03.028  0.382
2006 Affar el B, Luke MP, Gay F, Calvo D, Sui G, Weiss RS, Li E, Shi Y. Targeted ablation of Par-4 reveals a cell type-specific susceptibility to apoptosis-inducing agents. Cancer Research. 66: 3456-62. PMID 16585168 DOI: 10.1158/0008-5472.Can-05-0964  0.317
2006 Rosendorff A, Sakakibara S, Lu S, Kieff E, Xuan Y, DiBacco A, Shi Y, Shi Y, Gill G. NXP-2 association with SUMO-2 depends on lysines required for transcriptional repression. Proceedings of the National Academy of Sciences of the United States of America. 103: 5308-13. PMID 16567619 DOI: 10.1073/Pnas.0601066103  0.398
2006 Bates EA, Victor M, Jones AK, Shi Y, Hart AC. Differential contributions of Caenorhabditis elegans histone deacetylases to huntingtin polyglutamine toxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2830-8. PMID 16525063 DOI: 10.1523/Jneurosci.3344-05.2006  0.355
2005 Shi YJ, Matson C, Lan F, Iwase S, Baba T, Shi Y. Regulation of LSD1 histone demethylase activity by its associated factors. Molecular Cell. 19: 857-64. PMID 16140033 DOI: 10.1016/J.Molcel.2005.08.027  0.417
2005 Baumeister P, Luo S, Skarnes WC, Sui G, Seto E, Shi Y, Lee AS. Endoplasmic reticulum stress induction of the Grp78/BiP promoter: activating mechanisms mediated by YY1 and its interactive chromatin modifiers. Molecular and Cellular Biology. 25: 4529-40. PMID 15899857 DOI: 10.1128/Mcb.25.11.4529-4540.2005  0.346
2005 Whetstine JR, Ceron J, Ladd B, Dufourcq P, Reinke V, Shi Y. Regulation of tissue-specific and extracellular matrix-related genes by a class I histone deacetylase. Molecular Cell. 18: 483-90. PMID 15893731 DOI: 10.1016/J.Molcel.2005.04.006  0.392
2004 Shi Y, Lan F, Matson C, Mulligan P, Whetstine JR, Cole PA, Casero RA, Shi Y. Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell. 119: 941-53. PMID 15620353 DOI: 10.1016/j.cell.2004.12.012  0.302
2004 Alpatov R, Munguba GC, Caton P, Joo JH, Shi Y, Shi Y, Hunt ME, Sugrue SP. Nuclear speckle-associated protein Pnn/DRS binds to the transcriptional corepressor CtBP and relieves CtBP-mediated repression of the E-cadherin gene. Molecular and Cellular Biology. 24: 10223-35. PMID 15542832 DOI: 10.1128/Mcb.24.23.10223-10235.2004  0.389
2004 Chen J, Wall NR, Kocher K, Duclos N, Fabbro D, Neuberg D, Griffin JD, Shi Y, Gilliland DG. Stable expression of small interfering RNA sensitizes TEL-PDGFβR to inhibition with imatinib or rapamycin Journal of Clinical Investigation. 113: 1784-1791. PMID 15199413 DOI: 10.1172/Jci20673  0.338
2004 Lo MC, Gay F, Odom R, Shi Y, Lin R. Phosphorylation by the beta-catenin/MAPK complex promotes 14-3-3-mediated nuclear export of TCF/POP-1 in signal-responsive cells in C. elegans. Cell. 117: 95-106. PMID 15066285 DOI: 10.1016/S0092-8674(04)00203-X  0.305
2004 Walker AK, Shi Y, Blackwell TK. An extensive requirement for transcription factor IID-specific TAF-1 in Caenorhabditis elegans embryonic transcription. The Journal of Biological Chemistry. 279: 15339-47. PMID 14726532 DOI: 10.1074/Jbc.M310731200  0.365
2003 Lin X, Liang YY, Sun B, Liang M, Shi Y, Brunicardi FC, Shi Y, Feng XH. Smad6 recruits transcription corepressor CtBP to repress bone morphogenetic protein-induced transcription. Molecular and Cellular Biology. 23: 9081-93. PMID 14645520 DOI: 10.1128/Mcb.23.24.9081-9093.2003  0.33
2003 Shi Y, Blackwell TK. A Two-Tiered Transcription Regulation Mechanism that Protects Germ Cell Identity Molecular Cell. 12: 1062-1064. PMID 14636565 DOI: 10.1016/S1097-2765(03)00447-7  0.405
2003 Wall NR, Shi Y. Small RNA: Can RNA interference be exploited for therapy? Lancet. 362: 1401-1403. PMID 14585643 DOI: 10.1016/S0140-6736(03)14637-5  0.353
2003 Ding H, Schwarz DS, Keene A, Affar el B, Fenton L, Xia X, Shi Y, Zamore PD, Xu Z. Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis. Aging Cell. 2: 209-17. PMID 12934714 DOI: 10.1046/J.1474-9728.2003.00054.X  0.328
2003 Xia XG, Zhou H, Ding H, Affar el B, Shi Y, Xu Z. An enhanced U6 promoter for synthesis of short hairpin RNA. Nucleic Acids Research. 31: e100. PMID 12930974 DOI: 10.1093/Nar/Gng098  0.349
2003 Shi Y, Sawada J, Sui G, Affar el B, Whetstine JR, Lan F, Ogawa H, Luke MP, Nakatani Y, Shi Y. Coordinated histone modifications mediated by a CtBP co-repressor complex. Nature. 422: 735-8. PMID 12700765 DOI: 10.1038/Nature01550  0.438
2003 Gay F, Calvo D, Lo MC, Ceron J, Maduro M, Lin R, Shi Y. Acetylation regulates subcellular localization of the Wnt signaling nuclear effector POP-1. Genes & Development. 17: 717-22. PMID 12651889 DOI: 10.1101/Gad.1042403  0.355
2003 Shi Y. Mammalian RNAi for the masses Trends in Genetics. 19: 9-12. PMID 12493242 DOI: 10.1016/S0168-9525(02)00005-7  0.358
2002 Gaudilliere B, Shi Y, Bonni A. RNA interference reveals a requirement for myocyte enhancer factor 2A in activity-dependent neuronal survival. The Journal of Biological Chemistry. 277: 46442-6. PMID 12235147 DOI: 10.1074/Jbc.M206653200  0.337
2002 Shim EY, Walker AK, Shi Y, Blackwell TK. CDK-9/cyclin T (P-TEFb) is required in two postinitiation pathways for transcription in the C. elegans embryo. Genes & Development. 16: 2135-46. PMID 12183367 DOI: 10.1101/Gad.999002  0.343
2002 Sui G, Soohoo C, Affar el B, Gay F, Shi Y, Forrester WC, Shi Y. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 99: 5515-20. PMID 11960009 DOI: 10.1073/Pnas.082117599  0.365
2002 Dufourcq P, Victor M, Gay F, Calvo D, Hodgkin J, Shi Y. Functional requirement for histone deacetylase 1 in Caenorhabditis elegans gonadogenesis. Molecular and Cellular Biology. 22: 3024-34. PMID 11940660 DOI: 10.1128/Mcb.22.9.3024-3034.2002  0.396
2002 Victor M, Bei Y, Gay F, Calvo D, Mello C, Shi Y. HAT activity is essential for CBP-1-dependent transcription and differentiation in Caenorhabditis elegans. Embo Reports. 3: 50-5. PMID 11751575 DOI: 10.1093/Embo-Reports/Kvf006  0.386
2001 Calvo D, Victor M, Gay F, Sui G, Luke MP, Dufourcq P, Wen G, Maduro M, Rothman J, Shi Y. A POP-1 repressor complex restricts inappropriate cell type-specific gene transcription during Caenorhabditis elegans embryogenesis. The Embo Journal. 20: 7197-208. PMID 11742996 DOI: 10.1093/Emboj/20.24.7197  0.419
2001 Walker AK, Rothman JH, Shi Y, Blackwell TK. Distinct requirements for C.elegans TAF(II)s in early embryonic transcription. The Embo Journal. 20: 5269-79. PMID 11566890 DOI: 10.1093/Emboj/20.18.5269  0.311
2001 Oei SL, Shi Y. Poly(ADP-ribosyl)ation of transcription factor Yin Yang 1 under conditions of DNA damage Biochemical and Biophysical Research Communications. 285: 27-31. PMID 11437367 DOI: 10.1006/Bbrc.2001.5115  0.346
2001 Oei SL, Shi Y. Transcription factor Yin Yang 1 stimulates poly(ADP-ribosyl)ation and DNA repair. Biochemical and Biophysical Research Communications. 284: 450-454. PMID 11394900 DOI: 10.1006/Bbrc.2001.4985  0.367
2001 See RH, Calvo D, Shi Y, Kawa H, Luke MP, Yuan Z, Shi Y. Stimulation of p300-mediated transcription by the kinase MEKK1. The Journal of Biological Chemistry. 276: 16310-7. PMID 11278389 DOI: 10.1074/Jbc.M008113200  0.31
2000 Coull JJ, Romerio F, Sun JM, Volker JL, Galvin KM, Davie JR, Shi Y, Hansen U, Margolis DM. The human factors YY1 and LSF repress the human immunodeficiency virus type 1 long terminal repeat via recruitment of histone deacetylase 1. Journal of Virology. 74: 6790-9. PMID 10888618 DOI: 10.1128/Jvi.74.15.6790-6799.2000  0.33
2000 Walker AK, See R, Batchelder C, Kophengnavong T, Gronniger JT, Shi Y, Blackwell TK. A conserved transcription motif suggesting functional parallels between Caenorhabditis elegans SKN-1 and Cap'n'Collar-related basic leucine zipper proteins. The Journal of Biological Chemistry. 275: 22166-71. PMID 10764775 DOI: 10.1074/Jbc.M001746200  0.33
1999 Yuan ZM, Huang Y, Ishiko T, Nakada S, Utsugisawa T, Shioya H, Utsugisawa Y, Shi Y, Weichselbaum R, Kufe D. Function for p300 and not CBP in the apoptotic response to DNA damage. Oncogene. 18: 5714-7. PMID 10523850 DOI: 10.1038/Sj.Onc.1202930  0.307
1999 Donohoe ME, Zhang X, McGinnis L, Biggers J, Li E, Shi Y. Targeted disruption of mouse Yin Yang 1 transcription factor results in peri-implantation lethality. Molecular and Cellular Biology. 19: 7237-7244. PMID 10490658 DOI: 10.1128/Mcb.19.10.7237  0.302
1998 See RH, Shi Y. Adenovirus E1B 19,000-molecular-weight protein activates c-Jun N-terminal kinase and c-Jun-mediated transcription. Molecular and Cellular Biology. 18: 4012-4022. PMID 9632786 DOI: 10.1128/Mcb.18.7.4012  0.317
1998 Johnstone RW, Wang J, Tommerup N, Vissing H, Roberts T, Shi Y. Ciao 1 is a novel WD40 protein that interacts with the tumor suppressor protein WT1. Journal of Biological Chemistry. 273: 10880-10887. PMID 9556563 DOI: 10.1074/Jbc.273.18.10880  0.348
1998 Shi Y, Mello C. A CBP/p300 homolog specifies multiple differentiation pathways in Caenorhabditis elegans Genes and Development. 12: 943-955. PMID 9531533 DOI: 10.1101/Gad.12.7.943  0.391
1998 Kawasaki H, Song J, Eckner R, Ugai H, Chiu R, Taira K, Shi Y, Jones N, Yokoyama KK. p300 and ATF-2 are components of the DRF complex, which regulates retinoic acid- and E1A-mediated transcription of the c-jun gene in F9 cells. Genes & Development. 12: 233-45. PMID 9436983 DOI: 10.1101/Gad.12.2.233  0.341
1997 Galvin KM, Shi Y. Multiple mechanisms of transcriptional repression by YY1 Molecular and Cellular Biology. 17: 3723-3732. PMID 9199306 DOI: 10.1128/Mcb.17.7.3723  0.373
1996 Johnstone RW, See RH, Sells SF, Wang J, Muthukkumar S, Englert C, Haber DA, Licht JD, Sugrue SP, Roberts T, Rangnekar VM, Shi Y. A novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1. Molecular and Cellular Biology. 16: 6945-56. PMID 8943350 DOI: 10.1128/Mcb.16.12.6945  0.353
1996 Lee JS, See RH, Deng T, Shi Y. Adenovirus E1A Downregulates Cjun- And Junb-Mediated Transcription By Targeting Their Coactivator P300 Molecular and Cellular Biology. 16: 4312-4326. PMID 8754832 DOI: 10.1128/Mcb.16.8.4312  0.34
1996 Lee J, Zhang X, Shi Y. Differential Interactions of the CREB/ATF Family of Transcription Factors with p300 and Adenovirus E1A Journal of Biological Chemistry. 271: 17666-17674. DOI: 10.1074/Jbc.271.30.17666  0.321
1995 Lee JS, Galvin KM, See RH, Eckner R, Livingston D, Moran E, Shi Y. Relief of YY1 transcriptional repression by adenovirus E1A is mediated by E1A-associated protein p300. Genes & Development. 9: 1188-98. PMID 7758944 DOI: 10.1101/Gad.9.10.1188  0.3
1995 Reddy JC, Morris JC, Wang J, English MA, Haber DA, Shi Y, Licht JD. WT1-mediated transcriptional activation is inhibited by dominant negative mutant proteins Journal of Biological Chemistry. 270: 10878-10884. PMID 7738027 DOI: 10.1074/Jbc.270.18.10878  0.335
1995 Lee J, See RH, Galvin KM, Wang J, Shi Y. Functional interactions between YY1 and adenovirus E1A. Nucleic Acids Research. 23: 925-931. PMID 7731805 DOI: 10.1093/Nar/23.6.925  0.306
1993 Riggs KJ, Saleque S, Wong KK, Merrell KT, Lee JS, Shi Y, Calame K. Yin-yang 1 activates the c-myc promoter Molecular and Cellular Biology. 13: 7487-7495. PMID 8246966 DOI: 10.1128/Mcb.13.12.7487  0.303
1992 Lee T, Shi Y, Schwartz RJ. Displacement of BrdUrd-induced YY1 by serum response factor activates skeletal alpha-actin transcription in embryonic myoblasts. Proceedings of the National Academy of Sciences of the United States of America. 89: 9814-9818. PMID 1409704 DOI: 10.1073/Pnas.89.20.9814  0.313
1991 Seto E, Shi Y, Shenk T. YY1 is an initiator sequence-binding protein that directs and activates transcription in vitro Nature. 354: 241-245. PMID 1720509 DOI: 10.1038/354241A0  0.344
1991 Shi Y, Seto E, Chang LS, Shenk T. Transcriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A protein Cell. 67: 377-388. PMID 1655281 DOI: 10.1016/0092-8674(91)90189-6  0.321
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