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Bruce Furie - Publications

Affiliations: 
Harvard - BIDMC 
Area:
hemostasis and thrombosis
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143 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Schulman S, El-Darzi E, Florido MH, Friesen M, Merrill-Skoloff G, Brake MA, Schuster CR, Lin L, Westrick RJ, Cowan CA, Flaumenhaft R, BioResource N, Ouwehand WH, Peerlinck K, Freson K, ... ... Furie B, et al. A coagulation defect arising from heterozygous premature termination of tissue factor. The Journal of Clinical Investigation. PMID 32663190 DOI: 10.1172/Jci133780  0.742
2019 Eriksson O, Stopa J, Furie B. Identification of PDI Substrates by Mechanism-Based Kinetic Trapping. Methods in Molecular Biology (Clifton, N.J.). 1967: 165-182. PMID 31069770 DOI: 10.1007/978-1-4939-9187-7_10  0.785
2019 Eriksson O, Chiu J, Hogg PJ, Atkinson JP, Liszewski MK, Flaumenhaft R, Furie B. Thiol isomerase ERp57 targets and modulates the lectin pathway of complement activation. The Journal of Biological Chemistry. PMID 30670593 DOI: 10.1074/Jbc.Ra118.006792  0.791
2019 Zwicker JI, Schlechter BL, Stopa JD, Liebman H, Aggarwal A, Puligandla M, Caughey T, Bauer KA, Kuemmerle N, Wong E, Wun T, McLaughlin M, Hidalgo M, Neuberg D, Furie B, et al. Targeting protein disulfide isomerase with the flavonoid isoquercetin to improve hypercoagulability in advanced cancer. Jci Insight. PMID 30652973 DOI: 10.1172/Jci.Insight.125851  0.809
2018 Bekendam RH, Iyu D, Passam F, Stopa JD, De Ceunynck K, Muse O, Bendapudi PK, Garnier CL, Gopal S, Crescence L, Chiu J, Furie B, Panicot-Dubois L, Hogg PJ, Dubois C, et al. Protein disulfide isomerase regulation by nitric oxide maintains vascular quiescence and controls thrombus formation. Journal of Thrombosis and Haemostasis : Jth. PMID 30207066 DOI: 10.1111/Jth.14291  0.796
2018 Sharda A, Furie B. Regulatory role of thiol isomerases in thrombus formation. Expert Review of Hematology. 11: 437-448. PMID 29542339 DOI: 10.1080/17474086.2018.1452612  0.478
2018 Zwicker JI, Schlechter BL, Stopa JD, Liebman HA, Aggarwal A, Caughey T, Bauer KA, Kuemmerle N, Wong EY, Wun T, Mclaughlin M, Puligandla M, Neuberg DS, Furie B, Flaumenhaft RC. Targeting Protein Disulfide Isomerase with the Oral Flavonoid Isoquercetin Prevents Venous Thromboembolism in Advanced Cancer: Results of a Multi-Dose, Multi-Center, Phase II Clinical Trial (CATIQ Study) Blood. 132: 985-985. DOI: 10.1182/Blood-2018-99-114946  0.776
2017 Peng S, Xue G, Gong L, Fang C, Chen J, Yuan C, Chen Z, Yao L, Furie B, Huang M. A long-acting PAI-1 inhibitor reduce thrombus formation. Thrombosis and Haemostasis. PMID 28405670 DOI: 10.1160/Th16-11-0891  0.547
2017 Stopa JD, Baker KM, Grover SP, Flaumenhaft R, Furie B. Kinetic-based Trapping by Intervening Sequence Variants of the Active Sites of Protein Disulfide Isomerase Identifies Platelet Protein Substrates. The Journal of Biological Chemistry. PMID 28364042 DOI: 10.1074/Jbc.M116.771832  0.794
2017 Bowley SR, Fang C, Merrill-Skoloff G, Furie BC, Furie B. Protein disulfide isomerase secretion following vascular injury initiates a regulatory pathway for thrombus formation. Nature Communications. 8: 14151. PMID 28218242 DOI: 10.1038/Ncomms14151  0.778
2017 Stopa JD, Neuberg D, Puligandla M, Furie B, Flaumenhaft R, Zwicker JI. Protein disulfide isomerase inhibition blocks thrombin generation in humans by interfering with platelet factor V activation. Jci Insight. 2: e89373. PMID 28097231 DOI: 10.1172/Jci.Insight.89373  0.816
2016 Bekendam RH, Bendapudi PK, Lin L, Nag PP, Pu J, Kennedy DR, Feldenzer A, Chiu J, Cook KM, Furie B, Huang M, Hogg PJ, Flaumenhaft R. A substrate-driven allosteric switch that enhances PDI catalytic activity. Nature Communications. 7: 12579. PMID 27573496 DOI: 10.1038/Ncomms12579  0.7
2016 Flaumenhaft R, Furie B. Vascular thiol isomerases. Blood. 128: 893-901. PMID 27357699 DOI: 10.1182/Blood-2016-04-636456  0.639
2016 Gong L, Proulle V, Fang C, Hong Z, Lin Z, Liu M, Xue G, Yuan C, Lin L, Furie B, Flaumenhaft R, Andreasen P, Furie B, Huang M. A specific plasminogen activator inhibitor-1 antagonist derived from inactivated urokinase. Journal of Cellular and Molecular Medicine. PMID 27197780 DOI: 10.1111/Jcmm.12875  0.719
2016 Simeoni I, Stephens JC, Hu F, Deevi SV, Megy K, Bariana TK, Lentaigne C, Schulman S, Sivapalaratnam S, Vries MJ, Westbury SK, Greene D, Papadia S, Alessi MC, Attwood AP, ... ... Furie B, et al. A comprehensive high-throughput sequencing test for the diagnosis of inherited bleeding, thrombotic and platelet disorders. Blood. PMID 27084890 DOI: 10.1182/Blood-2015-12-688267  0.585
2016 Stopa JD, Neuberg DS, Puligandla M, Furie B, Flaumenhaft RC, Zwicker JI. PDI Inhibition Blocks Thrombin Generation in Humans By Interfering with Platelet Factor V Activation Blood. 128: 2628-2628. DOI: 10.1182/Blood.V128.22.2628.2628  0.818
2016 Fang C, Bowley SR, Furie BC, Furie B. Extracellular Protein Disulfide Isomerase Regulates Vitronectin during the Initiation of Thrombus Formation Blood. 128: 15-15. DOI: 10.1182/Blood.V128.22.15.15  0.532
2015 Schulman S, Bendapudi P, Sharda A, Chen V, Bellido-Martin L, Jasuja R, Furie BC, Flaumenhaft R, Furie B. EXTRACELLULAR THIOL ISOMERASES AND THEIR ROLE IN THROMBUS FORMATION. Antioxidants & Redox Signaling. PMID 26467859 DOI: 10.1089/Ars.2015.6530  0.692
2015 Lin L, Gopal S, Sharda A, Passam F, Bowley SR, Stopa J, Xue G, Yuan C, Furie BC, Flaumenhaft R, Huang M, Furie B. Quercetin-3-rutinoside Inhibits Protein Disulfide Isomerase by Binding to Its b'x Domain. The Journal of Biological Chemistry. 290: 23543-52. PMID 26240139 DOI: 10.1074/Jbc.M115.666180  0.774
2015 Westbury SK, Turro E, Greene D, Lentaigne C, Kelly AM, Bariana TK, Simeoni I, Pillois X, Attwood A, Austin S, Jansen SB, Bakchoul T, Crisp-Hihn A, Erber WN, Favier R, ... ... Furie B, et al. Human phenotype ontology annotation and cluster analysis to unravel genetic defects in 707 cases with unexplained bleeding and platelet disorders. Genome Medicine. 7: 36. PMID 25949529 DOI: 10.1186/S13073-015-0151-5  0.567
2015 Passam FH, Lin L, Gopal S, Stopa JD, Bellido-Martin L, Huang M, Furie BC, Furie B. Both platelet- and endothelial cell-derived ERp5 support thrombus formation in a laser-induced mouse model of thrombosis. Blood. 125: 2276-85. PMID 25624318 DOI: 10.1182/Blood-2013-12-547208  0.814
2015 Sharda A, Kim SH, Jasuja R, Gopal S, Flaumenhaft R, Furie BC, Furie B. Defective PDI release from platelets and endothelial cells impairs thrombus formation in Hermansky-Pudlak syndrome. Blood. 125: 1633-42. PMID 25593336 DOI: 10.1182/Blood-2014-08-597419  0.647
2015 Schulman S, Furie B. How I treat poisoning with vitamin K antagonists. Blood. 125: 438-42. PMID 25377783 DOI: 10.1182/Blood-2014-08-597781  0.563
2015 Flaumenhaft R, Furie B, Zwicker JI. Therapeutic implications of protein disulfide isomerase inhibition in thrombotic disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 16-23. PMID 25104801 DOI: 10.1161/Atvbaha.114.303410  0.65
2014 Proulle V, Furie RA, Merrill-Skoloff G, Furie BC, Furie B. Platelets are required for enhanced activation of the endothelium and fibrinogen in a mouse thrombosis model of APS. Blood. 124: 611-22. PMID 24825863 DOI: 10.1182/Blood-2014-02-554980  0.471
2014 Furie B, Flaumenhaft R. Thiol isomerases in thrombus formation. Circulation Research. 114: 1162-73. PMID 24677236 DOI: 10.1161/Circresaha.114.301808  0.674
2014 Furie B, Furie BC, Flaumenhaft R, Zwicker JI. Animal Models of Arterial and Venous Thrombosis Blood. 124. DOI: 10.1182/Blood.V124.21.Sci-2.Sci-2  0.69
2014 Bekendam RH, Srila G, Bendapudi PK, Dilks JR, Lin L, Bowley S, Stopa J, Huang M, Furie B, Croce K, Flaumenhaft R. Regulation of Protein Disulfide Isomerase By S-Nitrosylation Controls Its Function during Thrombus Formation Blood. 124: 93-93. DOI: 10.1182/Blood.V124.21.93.93  0.817
2014 Bendapudi PK, Bekendam RH, Lin L, Huang M, Furie B, Flaumenhaft R. ML359, a Small Molecule Inhibitor of Protein Disulfide Isomerase That Prevents Thrombus Formation and Inhibits Oxidoreductase but Not Transnitrosylase Activity Blood. 124: 2880-2880. DOI: 10.1182/Blood.V124.21.2880.2880  0.657
2012 Furie B, Furie BC. Formation of the clot. Thrombosis Research. 130: S44-6. PMID 23026660 DOI: 10.1016/J.Thromres.2012.08.272  0.449
2012 Fuster V, Bhatt DL, Califf RM, Michelson AD, Sabatine MS, Angiolillo DJ, Bates ER, Cohen DJ, Coller BS, Furie B, Hulot JS, Mann KG, Mega JL, Musunuru K, O'Donnell CJ, et al. Guided antithrombotic therapy: current status and future research direction: report on a National Heart, Lung and Blood Institute working group. Circulation. 126: 1645-62. PMID 23008471 DOI: 10.1161/Circulationaha.112.105908  0.324
2012 Cho J, Kennedy DR, Lin L, Huang M, Merrill-Skoloff G, Furie BC, Furie B. Protein disulfide isomerase capture during thrombus formation in vivo depends on the presence of β3 integrins. Blood. 120: 647-55. PMID 22653978 DOI: 10.1182/Blood-2011-08-372532  0.564
2012 Jasuja R, Passam FH, Kennedy DR, Kim SH, van Hessem L, Lin L, Bowley SR, Joshi SS, Dilks JR, Furie B, Furie BC, Flaumenhaft R. Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents. The Journal of Clinical Investigation. 122: 2104-13. PMID 22565308 DOI: 10.1172/Jci61228  0.809
2012 Weitz IC, Razavi P, Rochanda L, Zwicker J, Furie B, Manly D, Mackman N, Green R, Liebman HA. Eculizumab therapy results in rapid and sustained decreases in markers of thrombin generation and inflammation in patients with PNH independent of its effects on hemolysis and microparticle formation. Thrombosis Research. 130: 361-8. PMID 22542362 DOI: 10.1016/J.Thromres.2012.04.001  0.359
2012 Owens AP, Passam FH, Antoniak S, Marshall SM, McDaniel AL, Rudel L, Williams JC, Hubbard BK, Dutton JA, Wang J, Tobias PS, Curtiss LK, Daugherty A, Kirchhofer D, Luyendyk JP, ... ... Furie BC, ... ... Furie B, et al. Monocyte tissue factor-dependent activation of coagulation in hypercholesterolemic mice and monkeys is inhibited by simvastatin. The Journal of Clinical Investigation. 122: 558-68. PMID 22214850 DOI: 10.1172/Jci58969  0.361
2012 Zwicker JI, Lacroix R, Dignat-George F, Furie BC, Furie B. Measurement of platelet microparticles. Methods in Molecular Biology (Clifton, N.J.). 788: 127-39. PMID 22130705 DOI: 10.1007/978-1-61779-307-3_10  0.376
2011 Kroh HK, Panizzi P, Tchaikovski S, Baird TR, Wei N, Krishnaswamy S, Tans G, Rosing J, Furie B, Furie BC, Bock PE. Active site-labeled prothrombin inhibits prothrombinase in vitro and thrombosis in vivo. The Journal of Biological Chemistry. 286: 23345-56. PMID 21531712 DOI: 10.1074/Jbc.M111.230292  0.444
2011 Bellido-Martin L, Chen V, Jasuja R, Furie B, Furie BC. Imaging fibrin formation and platelet and endothelial cell activation in vivo Thrombosis and Haemostasis. 105: 776-782. PMID 21437353 DOI: 10.1160/Th10-12-0771  0.44
2011 Zwicker JI, Trenor CC, Furie BC, Furie B. Tissue factor-bearing microparticles and thrombus formation. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 728-33. PMID 21252066 DOI: 10.1161/Atvbaha.109.200964  0.364
2011 Lin Z, Jiang L, Yuan C, Jensen JK, Zhang X, Luo Z, Furie BC, Furie B, Andreasen PA, Huang M. Structural basis for recognition of urokinase-type plasminogen activator by plasminogen activator inhibitor-1. The Journal of Biological Chemistry. 286: 7027-32. PMID 21199867 DOI: 10.1074/Jbc.M110.204537  0.502
2011 Passam FH, Lin L, Huang M, Gibbins JM, Furie B, Furie BC. Role of Thiol Isomerase ERp5 in Thrombus Formation Blood. 118: 370-370. DOI: 10.1182/Blood.V118.21.370.370  0.385
2011 Jasuja R, Passam FH, Kennedy DR, Kim SH, Hessem Lv, Lin L, Joshi SS, Dilks JR, Furie B, Furie BC, Flaumenhaft RC. Protein Disulfide Isomerase Inhibitors: A New Class of Antithrombotic Agents Blood. 118: 369-369. DOI: 10.1182/Blood.V118.21.369.369  0.659
2010 Atkinson BT, Jasuja R, Chen VM, Nandivada P, Furie B, Furie BC. Laser-induced endothelial cell activation supports fibrin formation. Blood. 116: 4675-83. PMID 20675401 DOI: 10.1182/Blood-2010-05-283986  0.403
2010 Jasuja R, Furie B, Furie BC. Endothelium-derived but not platelet-derived protein disulfide isomerase is required for thrombus formation in vivo. Blood. 116: 4665-74. PMID 20668226 DOI: 10.1182/Blood-2010-04-278184  0.494
2010 Liu Z, Lin L, Yuan C, Nicolaes GA, Chen L, Meehan EJ, Furie B, Furie B, Huang M. Trp2313-His2315 of factor VIII C2 domain is involved in membrane binding: structure of a complex between the C2 domain and an inhibitor of membrane binding. The Journal of Biological Chemistry. 285: 8824-9. PMID 20089867 DOI: 10.1074/Jbc.M109.080168  0.554
2010 Martin LB, Furie B, Furie BC. Role of Protein Disulfide Isomerase In Thrombus Formation In a Collagen-Induced Pathway of Thrombus Formation Blood. 116: 345-345. DOI: 10.1182/Blood.V116.21.345.345  0.474
2010 Barthel SR, Wiese GK, Cho J, Opperman MJ, Hays DL, Siddiqui J, Pienta KJ, Furie B, Dimitroff CJ. Abstract 5178: Homing of circulating prostate cancer cells to bone is regulated by alpha 1,3 fucosyltransferase 7 Cancer Research. 70: 5178-5178. DOI: 10.1158/1538-7445.Am10-5178  0.313
2009 Furie B. Pathogenesis of thrombosis. Hematology. American Society of Hematology. Education Program. 255-8. PMID 20008207 DOI: 10.1182/Asheducation-2009.1.255  0.306
2009 Barthel SR, Wiese GK, Cho J, Opperman MJ, Hays DL, Siddiqui J, Pienta KJ, Furie B, Dimitroff CJ. Alpha 1,3 fucosyltransferases are master regulators of prostate cancer cell trafficking. Proceedings of the National Academy of Sciences of the United States of America. 106: 19491-6. PMID 19889975 DOI: 10.1073/Pnas.0906074106  0.316
2009 Chen V, Merrill-Skoloff G, Wang L, Chen S, Mackman N, Taubman M, Furie B, Furie B. Intravascular but Not Extravascular Tissue Factor Is Required for Fibrin Generation During Thrombus Formation in Cremaster Arterioles in Living Mice Subjected to Laser Injury. Blood. 114: 332-332. DOI: 10.1182/Blood.V114.22.332.332  0.41
2009 Jasuja R, Pauer H, Baird RT, Furie B, Furie B. Reduction of Phosphatidylserine Exposure through Copper Chelation Leads to Reduced Fibrin Deposition After Laser Induced Vascular Injury In Vivo. Blood. 114: 3049-3049. DOI: 10.1182/Blood.V114.22.3049.3049  0.428
2008 Furie B, Furie BC. Mechanisms of thrombus formation. The New England Journal of Medicine. 359: 938-49. PMID 18753650 DOI: 10.1056/Nejmra0801082  0.371
2008 Ngo JC, Huang M, Roth DA, Furie BC, Furie B. Crystal structure of human factor VIII: implications for the formation of the factor IXa-factor VIIIa complex. Structure (London, England : 1993). 16: 597-606. PMID 18400180 DOI: 10.1016/j.str.2008.03.001  0.403
2008 Huai Q, Zhou A, Lin L, Mazar AP, Parry GC, Callahan J, Shaw DE, Furie B, Furie BC, Huang M. Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes. Nature Structural & Molecular Biology. 15: 422-3. PMID 18376415 DOI: 10.1038/Nsmb.1404  0.485
2008 Cho J, Furie BC, Coughlin SR, Furie B. A critical role for extracellular protein disulfide isomerase during thrombus formation in mice. The Journal of Clinical Investigation. 118: 1123-31. PMID 18292814 DOI: 10.1172/Jci34134  0.476
2008 Jasuja R, Cho J, Furie B, Furie B. Endothelium but Not Platelet-Derived Protein Disulfide Isomerase Is Required for Fibrin Generation during Thrombus Formation in Vivo. Blood. 112: 691-691. DOI: 10.1182/Blood.V112.11.691.691  0.475
2007 Panicot-Dubois L, Thomas GM, Furie BC, Furie B, Lombardo D, Dubois C. Bile salt-dependent lipase interacts with platelet CXCR4 and modulates thrombus formation in mice and humans. The Journal of Clinical Investigation. 117: 3708-19. PMID 18037996 DOI: 10.1172/Jci32655  0.59
2007 Furie B, Furie BC. In vivo thrombus formation Journal of Thrombosis and Haemostasis. 5: 12-17. PMID 17635703 DOI: 10.1111/J.1538-7836.2007.02482.X  0.46
2007 Lin L, Huai Q, Huang M, Furie B, Furie BC. Crystal structure of the bovine lactadherin C2 domain, a membrane binding motif, shows similarity to the C2 domains of factor V and factor VIII. Journal of Molecular Biology. 371: 717-24. PMID 17583728 DOI: 10.1016/J.Jmb.2007.05.054  0.523
2007 Dubois C, Panicot-Dubois L, Gainor JF, Furie BC, Furie B. Thrombin-initiated platelet activation in vivo is vWF independent during thrombus formation in a laser injury model. The Journal of Clinical Investigation. 117: 953-60. PMID 17380206 DOI: 10.1172/Jci30537  0.576
2007 Zhu A, Sun H, Raymond RM, Furie BC, Furie B, Bronstein M, Kaufman RJ, Westrick R, Ginsburg D. Fatal hemorrhage in mice lacking gamma-glutamyl carboxylase. Blood. 109: 5270-5. PMID 17327402 DOI: 10.1182/Blood-2006-12-064188  0.339
2007 Zwicker JI, Furie BC, Furie B. Cancer-associated thrombosis. Critical Reviews in Oncology/Hematology. 62: 126-36. PMID 17293122 DOI: 10.1016/J.Critrevonc.2007.01.001  0.314
2007 Harakawa N, Shigeta A, Wato M, Merrill-Skoloff G, Furie BC, Furie B, Okazaki T, Domae N, Miyasaka M, Hirata T. P-selectin glycoprotein ligand-1 mediates L-selectin-independent leukocyte rolling in high endothelial venules of peripheral lymph nodes. International Immunology. 19: 321-9. PMID 17267415 DOI: 10.1093/Intimm/Dxl149  0.325
2007 Vandendries ER, Hamilton JR, Coughlin SR, Furie B, Furie BC. Par4 is required for platelet thrombus propagation but not fibrin generation in a mouse model of thrombosis. Proceedings of the National Academy of Sciences of the United States of America. 104: 288-92. PMID 17190826 DOI: 10.1073/Pnas.0610188104  0.457
2007 Jasuja R, Furie B, Furie BC. Endothelial Cell Thiol Isomerases: Potential Role in Thrombus Formation. Blood. 110: 3709-3709. DOI: 10.1182/Blood.V110.11.3709.3709  0.418
2007 Atkinson BT, Nandivada P, Furie B, Furie BC. Monitoring Endothelial Cell Activation In Vivo during Thrombus Formation. Blood. 110: 294-294. DOI: 10.1182/Blood.V110.11.294.294  0.341
2007 Cho J, Furie BC, Coughlin SR, Furie B. Protein Disulfide Isomerase Is Required for Fibrin Generation and Platelet Thrombus Formation In Vivo. Blood. 110: 292-292. DOI: 10.1182/Blood.V110.11.292.292  0.516
2007 Ngo JCK, Jacobs M, Furie BC, Furie B. Regulation of Tissue Factor Activity: Conformational Changes in Tissue Factor Associated with Cleavage of the Cysteine 186-Cysteine 209 Disulfide Bond. Blood. 110: 270-270. DOI: 10.1182/Blood.V110.11.270.270  0.323
2007 Furie B. Platelets: tetherballs in thrombus formation Blood. 109: 394-394. DOI: 10.1182/Blood-2006-10-053454  0.379
2006 Hansson K, Thämlitz AM, Furie B, Furie BC, Stenflo J. A single gamma-carboxyglutamic acid residue in a novel cysteine-rich secretory protein without propeptide. Biochemistry. 45: 12828-39. PMID 17042501 DOI: 10.1021/Bi061311A  0.321
2006 Furie B, Furie BC. Thrombus formation in a living mouse. Pathophysiology of Haemostasis and Thrombosis. 35: 1-4. PMID 16855338 DOI: 10.1159/000093534  0.327
2006 Furie BC, Furie B. Tissue factor pathway vs. collagen pathway for in vivo platelet activation. Blood Cells, Molecules & Diseases. 36: 135-8. PMID 16513378 DOI: 10.1016/J.Bcmd.2005.12.010  0.44
2006 Huai Q, Mazar AP, Kuo A, Parry GC, Shaw DE, Callahan J, Li Y, Yuan C, Bian C, Chen L, Furie B, Furie BC, Cines DB, Huang M. Structure of human urokinase plasminogen activator in complex with its receptor. Science (New York, N.Y.). 311: 656-9. PMID 16456079 DOI: 10.1126/Science.1121143  0.452
2006 Dubois C, Panicot-Dubois L, Merrill-Skoloff G, Furie B, Furie BC. Glycoprotein VI-dependent and -independent pathways of thrombus formation in vivo. Blood. 107: 3902-6. PMID 16455953 DOI: 10.1182/Blood-2005-09-3687  0.533
2006 Falati S, Patil S, Gross PL, Stapleton M, Merrill-Skoloff G, Barrett NE, Pixton KL, Weiler H, Cooley B, Newman DK, Newman PJ, Furie BC, Furie B, Gibbins JM. Platelet PECAM-1 inhibits thrombus formation in vivo Blood. 107: 535-541. PMID 16166583 DOI: 10.1182/Blood-2005-04-1512  0.43
2006 Lin L, Huai Q, Huang M, Furie B, Furie BC. Crystal Structure of the Bovine Lactadherin C2 Domain, a Potential Anticoagulant, Shows Similarity to Factor V and Factor VIII. Blood. 108: 194-194. DOI: 10.1182/Blood.V108.11.194.194  0.34
2006 Atkinson BT, Kos CA, Furie BC, Furie B. Rapid Activation of Unstimulated Endothelial Cells Containing Tissue Factor Following Laser-Induced Injury as Monitored Via Calcium Mobilization. Blood. 108: 1786-1786. DOI: 10.1182/Blood.V108.11.1786.1786  0.386
2006 Dubois C, Panicot-Dubois L, Gainor JF, Furie BC, Furie B. Thrombin-Dependent Platelet Activation Is VWF-Independent during Thrombus Formation In Vivo. Blood. 108: 1510-1510. DOI: 10.1182/Blood.V108.11.1510.1510  0.412
2005 Furie B, Furie BC. Thrombus formation in vivo. The Journal of Clinical Investigation. 115: 3355-62. PMID 16322780 DOI: 10.1172/Jci26987  0.386
2005 Gross PL, Furie BC, Merrill-Skoloff G, Chou J, Furie B. Leukocyte-versus microparticle-mediated tissue factor transfer during arteriolar thrombus development. Journal of Leukocyte Biology. 78: 1318-26. PMID 16204641 DOI: 10.1189/Jlb.0405193  0.363
2005 Arias-Salgado EG, Haj F, Dubois C, Moran B, Kasirer-Friede A, Furie BC, Furie B, Neel BG, Shattil SJ. PTP-1B is an essential positive regulator of platelet integrin signaling Journal of Cell Biology. 170: 837-845. PMID 16115959 DOI: 10.1083/Jcb.200503125  0.516
2005 Engelhardt B, Kempe B, Merfeld-Clauss S, Laschinger M, Furie B, Wild MK, Vestweber D. P-selectin glycoprotein ligand 1 is not required for the development of experimental autoimmune encephalomyelitis in SJL and C57BL/6 mice. Journal of Immunology (Baltimore, Md. : 1950). 175: 1267-75. PMID 16002731 DOI: 10.4049/Jimmunol.175.2.1267  0.336
2005 Furie B. P-selectin and blood coagulation: it's not only about inflammation any more. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 877-8. PMID 15863716 DOI: 10.1161/01.Atv.0000161049.53535.5D  0.359
2005 Sim DS, Flaumenhaft R, Furie BC, Furie B. Interactions of platelets, blood-borne tissue factor, and fibrin during arteriolar thrombus formation in vivo Microcirculation. 12: 301-311. PMID 15814438 DOI: 10.1080/10739680590925682  0.639
2005 Huai Q, Mazar AP, Parry G, Kuo A, Cines DB, Li Y, Yuan C, Bian C, Chen L, Furie B, Furie BC, Huang M. Crystal Structure of the Interaction of Human Urokinase Plasminogen Activitor with Its Receptor. Blood. 106: 683-683. DOI: 10.1182/Blood.V106.11.683.683  0.329
2005 Dubois C, Panicot-Dubois L, Furie BC, Furie B. Dynamics of Calcium Mobilization in Platelets during Thrombus Formation in a Living Mouse. Blood. 106: 649-649. DOI: 10.1182/Blood.V106.11.649.649  0.408
2005 Baird TR, Jacobs M, Tinklepaugh A, Gross P, Furie BC, Furie B. A Novel Thrombin Fluorogenic Substrate of High Affinity, Catalytic Efficiency and Selectivity. Blood. 106: 1953-1953. DOI: 10.1182/Blood.V106.11.1953.1953  0.367
2004 Sathish JG, Falati S, Croce K, Crump C, Furie BC, Furie B, Poole AW. Antibody cross-linking of human platelet P-selectin induces calcium entry by a mechanism dependent upon Fcgamma receptor IIA. Thrombosis and Haemostasis. 92: 598-605. PMID 15351857 DOI: 10.1160/Th03-11-0689  0.361
2004 Vandendries ER, Furie BC, Furie B. Role of P-selectin and PSGL-1 in coagulation and thrombosis. Thrombosis and Haemostasis. 92: 459-66. PMID 15351841 DOI: 10.1160/Th04-05-0306  0.405
2004 Schenone M, Furie BC, Furie B. The blood coagulation cascade Current Opinion in Hematology. 11: 272-277. PMID 15314527 DOI: 10.1097/01.Moh.0000130308.37353.D4  0.356
2004 Chou J, Mackman N, Merrill-Skoloff G, Pedersen B, Furie BC, Furie B. Hematopoietic cell-derived microparticle tissue factor contributes to fibrin formation during thrombus propagation. Blood. 104: 3190-7. PMID 15280200 DOI: 10.1182/Blood-2004-03-0935  0.365
2004 Falati S, Gross PL, Merrill-Skoloff G, Sim D, Flaumenhaft R, Celi A, Furie BC, Furie B. In vivo models of platelet function and thrombosis: study of real-time thrombus formation. Methods in Molecular Biology (Clifton, N.J.). 272: 187-97. PMID 15226545 DOI: 10.1385/1-59259-782-3:187  0.613
2004 Furie B, Furie BC. Role of platelet P-selectin and microparticle PSGL-1 in thrombus formation. Trends in Molecular Medicine. 10: 171-8. PMID 15059608 DOI: 10.1016/J.Molmed.2004.02.008  0.441
2004 Huang M, Furie BC, Furie B. Crystal structure of the calcium-stabilized human factor IX Gla domain bound to a conformation-specific anti-factor IX antibody. The Journal of Biological Chemistry. 279: 14338-46. PMID 14722079 DOI: 10.1074/Jbc.M314011200  0.497
2004 Sim DS, Merrill-Skoloff G, Furie BC, Furie B, Flaumenhaft R. Initial accumulation of platelets during arterial thrombus formation in vivo is inhibited by elevation of basal cAMP levels. Blood. 103: 2127-34. PMID 14645013 DOI: 10.1182/Blood-2003-04-1133  0.65
2004 Dubois C, Panicot-Dubois L, Furie B, Furie BC. Importance of GPVI in Platelet Activation and Thrombus Formation In Vivo. Blood. 104: 842-842. DOI: 10.1182/Blood.V104.11.842.842  0.46
2004 Panicot-Dubois L, Dubois C, Furie BC, Furie B, Lombardo D. A Role for Bile Salt-Dependent Lipase in Platelet Activation and in Thrombus Formation in Vivo. Blood. 104: 3526-3526. DOI: 10.1182/Blood.V104.11.3526.3526  0.48
2004 Arias-Salgado EG, Haj F, Dubois C, Furie BC, Furie B, Neel BG, Shattil SJ. PTP-1B Is the Protein Tyrosine Phosphatase That Initiates Integrin αIIbβ3 Outside-In Signaling in Platelets. Blood. 104: 330-330. DOI: 10.1182/Blood.V104.11.330.330  0.423
2004 Dubois C, Panicot-Dubois L, Furie BC, Furie B. Direct Real Time Visualization of Platelet Calclium Signaling In Vivo: Role of Platelet Activation and Thrombus Formation in a Living Mouse. Blood. 104: 325-325. DOI: 10.1182/Blood.V104.11.325.325  0.408
2004 Regan Baird T, Gailani D, Furie B, Furie BC. Factor XI Deficient Mice Have Reduced Platelet Accumulation and Fibrin Deposition after Laser Injury. Blood. 104: 218-218. DOI: 10.1182/Blood.V104.11.218.218  0.389
2003 Huang M, Rigby AC, Morelli X, Grant MA, Huang G, Furie B, Seaton B, Furie BC. Structural basis of membrane binding by Gla domains of vitamin K-dependent proteins. Nature Structural Biology. 10: 751-6. PMID 12923575 DOI: 10.1038/Nsb971  0.51
2003 Celi A, Merrill-Skoloff G, Gross P, Falati S, Sim DS, Flaumenhaft R, Furie BC, Furie B. Thrombus formation: Direct real-time observation and digital analysis of thrombus assembly in a living mouse by confocal and widefield intravital microscopy Journal of Thrombosis and Haemostasis. 1: 60-68. PMID 12871540 DOI: 10.1046/J.1538-7836.2003.T01-1-00033.X  0.591
2003 Falati S, Liu Q, Gross P, Merrill-Skoloff G, Chou J, Vandendries E, Celi A, Croce K, Furie BC, Furie B. Accumulation of tissue factor into developing thrombi in vivo is dependent upon microparticle P-selectin glycoprotein ligand 1 and platelet P-selectin. The Journal of Experimental Medicine. 197: 1585-98. PMID 12782720 DOI: 10.1084/Jem.20021868  0.439
2003 Blostein MD, Furie BC, Rajotte I, Furie B. The Gla domain of factor IXa binds to factor VIIIa in the tenase complex. The Journal of Biological Chemistry. 278: 31297-302. PMID 12782629 DOI: 10.1074/Jbc.M302840200  0.332
2002 Falati S, Gross P, Merrill-Skoloff G, Furie BC, Furie B. Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse. Nature Medicine. 8: 1175-81. PMID 12244306 DOI: 10.1038/Nm782  0.377
2001 Furie B, Furie BC, Flaumenhaft R. A journey with platelet P-selectin: the molecular basis of granule secretion, signalling and cell adhesion. Thrombosis and Haemostasis. 86: 214-221. DOI: 10.1055/S-0037-1616219  0.624
2000 Falls LA, Furie B, Furie BC. Role of phosphatidylethanolamine in assembly and function of the factor IXa - Factor VIIIa complex on membrane surfaces Biochemistry. 39: 13216-13222. PMID 11052674 DOI: 10.1021/Bi0009789  0.307
2000 Blostein MD, Rigby AC, Furie BC, Furie B, Gilbert GE. Amphipathic helices support function of blood coagulation factor IXa. Biochemistry. 39: 12000-6. PMID 11009614 DOI: 10.1021/Bi000655C  0.318
2000 Blostein MD, Rigby AC, Jacobs M, Furie B, Furie BC. The Gla domain of human prothrombin has a binding site for factor Va. The Journal of Biological Chemistry. 275: 38120-6. PMID 10973980 DOI: 10.1074/Jbc.M007174200  0.337
1999 Yang J, Hirata T, Croce K, Merrill-Skoloff G, Tchernychev B, Williams E, Flaumenhaft R, Furie BC, Furie B. Targeted Gene Disruption Demonstrates That P-Selectin Glycoprotein Ligand 1 (Psgl-1) Is Required for P-Selectin–Mediated but Not E-Selectin–Mediated Neutrophil Rolling and Migration Journal of Experimental Medicine. 190: 1769-1782. PMID 10601352 DOI: 10.1084/Jem.190.12.1769  0.53
1999 Croce K, Flaumenhaft R, Rivers M, Furie B, Furie BC, Herman IM, Potter DA. Inhibition of calpain blocks platelet secretion, aggregation, and spreading. The Journal of Biological Chemistry. 274: 36321-7. PMID 10593923 DOI: 10.1074/Jbc.274.51.36321  0.649
1999 Flaumenhaft R, Furie B, Furie BC. Alpha-granule secretion from alpha-toxin permeabilized, MgATP-exposed platelets is induced independently by H+ and Ca2+. Journal of Cellular Physiology. 179: 1-10. PMID 10082126 DOI: 10.1002/(Sici)1097-4652(199904)179:1<1::Aid-Jcp1>3.0.Co;2-E  0.559
1999 Flaumenhaft R, Croce K, Chen E, Furie B, Furie BC. Proteins of the exocytotic core complex mediate platelet alpha-granule secretion. Roles of vesicle-associated membrane protein, SNAP-23, and syntaxin 4. Journal of Biological Chemistry. 274: 2492-2501. PMID 9891020 DOI: 10.1074/Jbc.274.4.2492  0.614
1999 Yang J, Furie BC, Furie B. The biology of P-selectin glycoprotein ligand-1: its role as a selectin counterreceptor in leukocyte-endothelial and leukocyte-platelet interaction. Thrombosis and Haemostasis. 81: 1-7. DOI: 10.1055/S-0037-1614407  0.357
1998 Pellegrini G, Malandra R, Celi A, Furie BC, Furie B, Lorenzet R. 12-Hydroxyeicosatetraenoic acid upregulates P-selectin-induced tissue factor activity on monocytes Febs Letters. 441: 463-466. PMID 9891991 DOI: 10.1016/S0014-5793(98)01610-X  0.335
1998 Croce K, Freedman SJ, Furie BC, Furie B. Interaction between soluble P-selectin and soluble P-selectin glycoprotein ligand 1: equilibrium binding analysis. Biochemistry. 37: 16472-80. PMID 9843413 DOI: 10.1021/Bi981341G  0.345
1997 Li S, Furie BC, Furie B, Walsh CT. The propeptide of the vitamin K-dependent carboxylase substrate accelerates formation of the gamma-glutamyl carbanion intermediate. Biochemistry. 36: 6384-90. PMID 9174354 DOI: 10.1021/Bi962816B  0.323
1996 Freedman SJ, Sanford DG, Bachovchin WW, Furie BC, Baleja JD, Furie B. Structure and function of the epidermal growth factor domain of P-selectin. Biochemistry. 35: 13733-44. PMID 8901515 DOI: 10.1021/Bi9610257  0.343
1995 Yamada M, Kuliopulos A, Nelson NP, Roth DA, Furie B, Furie BC, Walsh CT. Localization of the factor IX propeptide binding site on recombinant vitamin K dependent carboxylase using benzoylphenylalanine photoaffinity peptide inactivators. Biochemistry. 34: 481-9. PMID 7819240 DOI: 10.1021/Bi00002A012  0.306
1994 Kansas GS, Saunders KB, Ley K, Zakrzewicz A, Gibson RM, Furie BC, Furie B, Tedder TF. A role for the epidermal growth factor-like domain of P-selectin in ligand recognition and cell adhesion. The Journal of Cell Biology. 124: 609-18. PMID 7508943 DOI: 10.1083/Jcb.124.4.609  0.33
1993 Rehemtulla A, Roth DA, Wasley LC, Kuliopulos A, Walsh CT, Furie B, Furie BC, Kaufman RJ. In vitro and in vivo functional characterization of bovine vitamin K-dependent gamma-carboxylase expressed in Chinese hamster ovary cells. Proceedings of the National Academy of Sciences of the United States of America. 90: 4611-5. PMID 8506307 DOI: 10.1073/Pnas.90.10.4611  0.307
1993 Limentani SA, Roth DA, Furie BC, Furie B. Recombinant blood clotting proteins for hemophilia therapy Seminars in Thrombosis and Hemostasis. 19: 62-72. PMID 8456325 DOI: 10.1055/S-2007-994007  0.316
1993 Kotkow KJ, Roth DA, Porter TJ, Furie BC, Furie B. Role of propeptide in vitamin K-dependent gamma-carboxylation. Methods in Enzymology. 222: 435-49. PMID 8412809 DOI: 10.1016/0076-6879(93)22028-E  0.315
1993 Roth DA, Rehemtulla A, Kaufman RJ, Walsh CT, Furie B, Furie BC. Expression of bovine vitamin K-dependent carboxylase activity in baculovirus-infected insect cells. Proceedings of the National Academy of Sciences of the United States of America. 90: 8372-6. PMID 8378308 DOI: 10.1073/Pnas.90.18.8372  0.301
1992 Kuliopulos A, Cieurzo CE, Furie B, Furie BC, Walsh CT. N-bromoacetyl-peptide substrate affinity labeling of vitamin K dependent carboxylaset Biochemistry. 31: 9436-9444. PMID 1390725 DOI: 10.1021/Bi00154A016  0.333
1992 Koedam JA, Cramer EM, Briend E, Furie B, Furie BC, Wagner DD. P-selectin, a granule membrane protein of platelets and endothelial cells, follows the regulated secretory pathway in AtT-20 cells. The Journal of Cell Biology. 116: 617-25. PMID 1370497 DOI: 10.1083/Jcb.116.3.617  0.36
1989 Palabrica TM, Furie BC, Konstam MA, Aronovitz MJ, Connolly R, Brockway BA, Ramberg KL, Furie B. Thrombus imaging in a primate model with antibodies specific for an external membrane protein of activated platelets Proceedings of the National Academy of Sciences of the United States of America. 86: 1036-1040. PMID 2521733 DOI: 10.1073/Pnas.86.3.1036  0.441
1989 Larsen E, Celi A, Gilbert GE, Furie BC, Erban JK, Bonfanti R, Wagner DD, Furie B. PADGEM protein: a receptor that mediates the interaction of activated platelets with neutrophils and monocytes. Cell. 59: 305-12. PMID 2478294 DOI: 10.1016/0092-8674(89)90292-4  0.466
1989 Berman CL, Yeo EL, Furie BC, Furie B. [27] PADGEM protein Methods in Enzymology. 169: 311-326. PMID 2469941 DOI: 10.1016/0076-6879(89)69071-4  0.389
1986 Diuguid DL, Rabiet MJ, Furie BC, Liebman HA, Furie B. Molecular basis of hemophilia B: a defective enzyme due to an unprocessed propeptide is caused by a point mutation in the factor IX precursor Proceedings of the National Academy of Sciences of the United States of America. 83: 5803-5807. PMID 3461460 DOI: 10.1073/Pnas.83.16.5803  0.31
1986 Berman CL, Yeo EL, Wencel-Drake JD, Furie BC, Ginsberg MH, Furie B. A platelet alpha granule membrane protein that is associated with the plasma membrane after activation. Characterization and subcellular localization of platelet activation-dependent granule-external membrane protein. The Journal of Clinical Investigation. 78: 130-7. PMID 2941452 DOI: 10.1172/Jci112542  0.441
1985 Liebman HA, Limentani SA, Furie BC, Furie B. Immunoaffinity purification of factor IX (Christmas factor) by using conformation-specific antibodies directed against the factor IX-metal complex Proceedings of the National Academy of Sciences of the United States of America. 82: 3879-3883. PMID 2408269 DOI: 10.1073/Pnas.82.11.3879  0.333
1985 Asano T, Furie B, Furie B. Platelet binding properties of monoclonal lupus autoantibodies produced by human hybridomas Blood. 66: 1254-1260. DOI: 10.1182/blood.v66.6.1254.bloodjournal6661254  0.316
1985 Asano T, Furie B, Furie B. Platelet binding properties of monoclonal lupus autoantibodies produced by human hybridomas Blood. 66: 1254-1260. DOI: 10.1182/BLOOD.V66.6.1254.1254  0.317
1984 Hsu-Lin S, Berman CL, Furie BC, August D, Furie B. A platelet membrane protein expressed during platelet activation and secretion. Studies using a monoclonal antibody specific for thrombin-activated platelets. Journal of Biological Chemistry. 259: 9121-9126. DOI: 10.1016/s0021-9258(17)47274-7  0.323
1982 Furie B, Blanchard RA, Robison DJ, Tai MM, Furie BC. [5] Conformation-specific antibodies: approach to the study of the vitamin K-dependent blood coagulation proteins Methods in Enzymology. 84: 60-83. PMID 7098972 DOI: 10.1016/0076-6879(82)84007-X  0.309
1982 Shoenfeld Y, Hsu-Lin SC, Gabriels JE, Silberstein LE, Furie BC, Furie B, Stollar BD, Schwartz RS. Production of autoantibodies by human-human hybridomas. Journal of Clinical Investigation. 70: 205-208. PMID 7085884 DOI: 10.1172/Jci110595  0.301
1978 Feldmann RJ, Bing DH, Furie BC, Furie B. Interactive computer surface graphics approach to study of the active site of bovine trypsin Proceedings of the National Academy of Sciences of the United States of America. 75: 5409-5412. PMID 281690 DOI: 10.1073/Pnas.75.11.5409  0.347
1976 Furie BC, Furie B. [16] Coagulant protein of Russell's viper venom Methods in Enzymology. 45: 191-205. PMID 1011991 DOI: 10.1016/S0076-6879(76)45019-X  0.411
1975 Young NS, Curd JG, Eastlake A, Furie B, Schechter AN. Isolation of antibodies specific to sickle hemoglobin by affinity chromatography using a synthetic peptide Proceedings of the National Academy of Sciences of the United States of America. 72: 4759-4763. PMID 813215 DOI: 10.1073/Pnas.72.12.4759  0.497
1974 Furie B, Griffin JH, Feldmann RJ, Sokoloski EA, Schechter AN. The active site of staphylococcal nuclease: paramagnetic relaxation of bound nucleotide inhibitor nuclei by lanthanide ions. Proceedings of the National Academy of Sciences of the United States of America. 71: 2833-7. PMID 4528015 DOI: 10.1073/Pnas.71.7.2833  0.482
1974 Furie BC, Furie B. [75] Purification of proteins involved in Ca(II)-dependent protein-protein interactions (coagulant protein of Russell's viper venom) Methods in Enzymology. 34: 592-594. PMID 4449476 DOI: 10.1016/S0076-6879(74)34078-5  0.359
1974 Furie B, Schechter AN, Sachs DH, Anfinsen CB. Antibodies to the unfolded form of a helix-rich region in staphylococcal nuclease. Biochemistry. 13: 1561-6. PMID 4364704 DOI: 10.1021/Bi00705A001  0.618
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