Louis J. Ignarro - Publications

Affiliations: 
Molecular and Medical Pharmacology University of California, Los Angeles, Los Angeles, CA 
Area:
regulation and modulation of nitric oxide (NO) production and cytotoxicity in macrophages, vascular cells, and tumor cells
Website:
http://www.nobelprize.org/nobel_prizes/medicine/laureates/1998/ignarro-bio.html

326 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Karlsson JOG, Jynge P, Ignarro LJ. Exacerbated Neuropathy in POLAR A and M Trials Due to Redox Interaction of PledOx-Associated Mn and Oxaliplatin-Associated Pt. Antioxidants (Basel, Switzerland). 12. PMID 36978857 DOI: 10.3390/antiox12030608  0.221
2021 Karlsson JOG, Jynge P, Ignarro LJ. The Damaging Outcome of the POLAR Phase III Trials Was Due to Avoidable Time-Dependent Redox Interaction between Oxaliplatin and PledOx. Antioxidants (Basel, Switzerland). 10. PMID 34943040 DOI: 10.3390/antiox10121937  0.228
2021 Ignarro LJ. Nitric Oxide: A Unique Endogenous Signaling Molecule in Vascular Biology (Nobel Lecture). Angewandte Chemie (International Ed. in English). 38: 1882-1892. PMID 34182699 DOI: 10.1002/(SICI)1521-3773(19990712)38:13/14<1882::AID-ANIE1882>3.0.CO;2-V  0.426
2021 Dóka É, Arnér ESJ, Schmidt EE, Dick TP, van der Vliet A, Yang J, Szatmári R, Ditrói T, Wallace JL, Cirino G, Olson K, Motohashi H, Fukuto JM, Pluth MD, Feelisch M, ... ... Ignarro LJ, et al. Comment on "Evidence that the ProPerDP method is inadequate for protein persulfidation detection due to lack of specificity". Science Advances. 7. PMID 33883133 DOI: 10.1126/sciadv.abe7006  0.22
2020 Karlsson JOG, Jynge P, Ignarro LJ. May Mangafodipir or Other SOD Mimetics Contribute to Better Care in COVID-19 Patients? Antioxidants (Basel, Switzerland). 9. PMID 33050459 DOI: 10.3390/antiox9100971  0.311
2020 Ignarro LJ. Inhaled Nitric Oxide and COVID-19. British Journal of Pharmacology. PMID 32346862 DOI: 10.1111/Bph.15085  0.475
2019 Karlsson JOG, Jynge P, Lundström I, Ignarro LJ. Letter in response to: "Randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with the 12-h regimen of N acetylcysteine for paracetamol overdose-the PP100-01 for Overdose of Paracetamol (POP) trial: study protocol for a randomised controlled trial". Trials. 20: 380. PMID 31234946 DOI: 10.1186/S13063-019-3476-3  0.314
2019 Ignarro LJ. Nitric oxide is not just blowing in the wind. British Journal of Pharmacology. 176: 131-134. PMID 30556130 DOI: 10.1111/Bph.14540  0.416
2018 Fukuto JM, Ignarro LJ, Nagy P, Wink DA, Kevil CG, Feelisch M, Cortese-Krott MM, Bianco CL, Kumagai Y, Hobbs AJ, Lin J, Ida T, Akaike T. Biological Hydropersulfides and Related Polysulfides: A New Concept and Perspective in Redox Biology. Febs Letters. PMID 29754415 DOI: 10.1002/1873-3468.13090  0.368
2015 Karlsson JO, Ignarro LJ, Lundström I, Jynge P, Almén T. Calmangafodipir [Ca4Mn(DPDP)5], mangafodipir (MnDPDP) and MnPLED with special reference to their SOD mimetic and therapeutic properties. Drug Discovery Today. 20: 411-21. PMID 25463039 DOI: 10.1016/J.Drudis.2014.11.008  0.373
2015 Karlsson JOG, Ignarro LJ, Lundström I, Jynge P, Almén T. Calmangafodipir [Ca4Mn(DPDP)5], mangafodipir (MnDPDP) and MnPLED with special reference to their SOD mimetic and therapeutic properties Drug Discovery Today. 20: 411-421. DOI: 10.1016/j.drudis.2014.11.008  0.204
2014 Meldrum DR, Burnett AL, Dorey G, Esposito K, Ignarro LJ. Erectile hydraulics: Maximizing inflow while minimizing outflow Journal of Sexual Medicine. 11: 1208-1220. PMID 24521101 DOI: 10.1111/Jsm.12457  0.332
2014 Hayashi T, Kotani H, Yamaguchi T, Taguchi K, Iida M, Ina K, Maeda M, Kuzuya M, Hattori Y, Ignarro LJ. Endothelial cellular senescence is inhibited by liver X receptor activation with an additional mechanism for its atheroprotection in diabetes Proceedings of the National Academy of Sciences of the United States of America. 111: 1168-1173. PMID 24398515 DOI: 10.1073/Pnas.1322153111  0.434
2013 Napoli C, Paolisso G, Casamassimi A, Al-Omran M, Barbieri M, Sommese L, Infante T, Ignarro LJ. Effects of nitric oxide on cell proliferation: novel insights. Journal of the American College of Cardiology. 62: 89-95. PMID 23665095 DOI: 10.1016/J.Jacc.2013.03.070  0.439
2013 Kwon KJ, Kim JN, Kim MK, Kim SY, Cho KS, Jeon SJ, Kim HY, Ryu JH, Han SY, Cheong JH, Ignarro LJ, Han SH, Shin CY. Neuroprotective effects of valproic acid against hemin toxicity: possible involvement of the down-regulation of heme oxygenase-1 by regulating ubiquitin-proteasomal pathway. Neurochemistry International. 62: 240-50. PMID 23298644 DOI: 10.1016/J.Neuint.2012.12.019  0.404
2012 Zheng M, Kim SK, Joe Y, Back SH, Cho HR, Kim HP, Ignarro LJ, Chung HT. Sensing endoplasmic reticulum stress by protein kinase RNA-like endoplasmic reticulum kinase promotes adaptive mitochondrial DNA biogenesis and cell survival via heme oxygenase-1/carbon monoxide activity Faseb Journal. 26: 2558-2568. PMID 22391129 DOI: 10.1096/Fj.11-199604  0.385
2012 de Nigris F, Rienzo M, Sessa M, Infante T, Cesario E, Ignarro LJ, Al-Omran M, Giordano A, Palinski W, Napoli C. Glycoxydation promotes vascular damage Via MAPK-ERK/JNK pathways Journal of Cellular Physiology. 227: 3639-3647. PMID 22331607 DOI: 10.1002/Jcp.24070  0.421
2012 Ma L, Yang Y, Sikka SC, Kadowitz PJ, Ignarro LJ, Abdel-Mageed AB, Hellstrom WJG. Adipose tissue-derived stem cell-seeded small intestinal submucosa for tunica albuginea grafting and reconstruction Proceedings of the National Academy of Sciences of the United States of America. 109: 2090-2095. PMID 22308363 DOI: 10.1073/Pnas.1113810109  0.341
2012 Fukuto JM, Carrington SJ, Tantillo DJ, Harrison JG, Ignarro LJ, Freeman BA, Chen A, Wink DA. Small molecule signaling agents: The integrated chemistry and biochemistry of nitrogen oxides, oxides of carbon, dioxygen, hydrogen sulfide, and their derived species Chemical Research in Toxicology. 25: 769-793. PMID 22263838 DOI: 10.1021/Tx2005234  0.376
2012 Zhang R, Jack GS, Rao N, Zuk P, Ignarro LJ, Wu B, Rodríguez LV. Nuclear fusion-independent smooth muscle differentiation of human adipose-derived stem cells induced by a smooth muscle environment Stem Cells. 30: 481-490. PMID 22213158 DOI: 10.1002/Stem.1023  0.367
2012 Meldrum DR, Gambone JC, Morris MA, Esposito K, Giugliano D, Ignarro LJ. Lifestyle and metabolic approaches to maximizing erectile and vascular health International Journal of Impotence Research. 24: 61-68. PMID 22072232 DOI: 10.1038/Ijir.2011.51  0.45
2012 Ma L, Serefoglu EC, Yang Y, Abdel-Mageed AB, Sikka SC, Kadowitz PJ, Ignarro LJ, Hellstrom WJ. 213 ADIPOSE-DERIVED STEM CELL-SEEDED SMALL INTESTINAL SUBMUCOSA IN RAT PEYRONIE'S DISEASE MODEL FOR TUNICA ALBUGINEA GRAFTING AND RECONSTRUCTION Journal of Urology. 187. DOI: 10.1016/J.Juro.2012.02.266  0.332
2012 Napoli C, Bruzzese G, Ignarro LJ, Crimi E, De Nigris F, Williams-Ignarro S, Libardi S, Sommese L, Fiorito C, Mancini FP, Cacciatore F, Liguori A. Long-term treatment with sulfhydryl angiotensin-converting enzyme inhibition reduces carotid intima-media thickening and improves the nitric oxide/oxidative stress pathways in newly diagnosed patients with mild to moderate primary hypertension Cardiovascular Therapy and Prevention (Russian Federation). 11: 93-101.  0.381
2011 Meldrum DR, Gambone JC, Morris MA, Meldrum DAN, Esposito K, Ignarro LJ. The link between erectile and cardiovascular health: The canary in the coal mine American Journal of Cardiology. 108: 599-606. PMID 21624550 DOI: 10.1016/J.Amjcard.2011.03.093  0.419
2011 Cacciatore F, Bruzzese G, Vitale DF, Liguori A, de Nigris F, Fiorito C, Infante T, Donatelli F, Minucci PB, Ignarro LJ, Napoli C. Effects of ACE inhibition on circulating endothelial progenitor cells, vascular damage, and oxidative stress in hypertensive patients. European Journal of Clinical Pharmacology. 67: 877-83. PMID 21445638 DOI: 10.1007/s00228-011-1029-0  0.366
2011 Kwon KJ, Cho KS, Lee SH, Kim JN, Joo SH, Ryu JH, Ignarro LJ, Han SH, Shin CY. Regulation of tissue plasminogen activator/plasminogen activator inhibitor-1 by hydrocortisone in rat primary astrocytes. Journal of Neuroscience Research. 89: 1059-69. PMID 21412817 DOI: 10.1002/Jnr.22619  0.411
2011 Matsui-Hirai H, Hayashi T, Yamamoto S, Ina K, Maeda M, Kotani H, Iguchi A, Ignarro LJ, Hattori Y. Dose-dependent modulatory effects of insulin on glucose-induced endothelial senescence in vitro and in vivo: A relationship between telomeres and nitric oxide Journal of Pharmacology and Experimental Therapeutics. 337: 591-599. PMID 21357660 DOI: 10.1124/Jpet.110.177584  0.378
2011 Napoli C, Giordano A, Casamassimi A, Pentimalli F, Ignarro LJ, De Nigris F. Directed in vivo angiogenesis assay and the study of systemic neoangiogenesis in cancer International Journal of Cancer. 128: 1505-1508. PMID 21280032 DOI: 10.1002/Ijc.25743  0.364
2011 Kim JW, Lee SH, Ko HM, Kwon KJ, Cho KS, Choi CS, Park JH, Kim HY, Lee J, Han SH, Ignarro LJ, Cheong JH, Kim WK, Shin CY. Biphasic regulation of tissue plasminogen activator activity in ischemic rat brain and in cultured neural cells: essential role of astrocyte-derived plasminogen activator inhibitor-1. Neurochemistry International. 58: 423-33. PMID 21193004 DOI: 10.1016/J.Neuint.2010.12.020  0.393
2011 Napoli C, Hayashi T, Cacciatore F, Casamassimi A, Casini C, Al-Omran M, Ignarro LJ. Endothelial progenitor cells as therapeutic agents in the microcirculation: An update Atherosclerosis. 215: 9-22. PMID 21126740 DOI: 10.1016/J.Atherosclerosis.2010.10.039  0.388
2011 Kwon KJ, Kim JN, Kim MK, Lee J, Ignarro LJ, Kim HJ, Shin CY, Han SH. Melatonin synergistically increases resveratrol-induced heme oxygenase-1 expression through the inhibition of ubiquitin-dependent proteasome pathway: A possible role in neuroprotection Journal of Pineal Research. 50: 110-123. PMID 21073519 DOI: 10.1111/J.1600-079X.2010.00820.X  0.449
2011 Ignarro LJ. IL1 Nitric oxide as a mediator of erectile function The Japanese Journal of Urology. 102: 63. DOI: 10.5980/Jpnjurol.102.63  0.424
2011 Napoli C, Ignarro LJ. Nitric Oxide in the Development of Vascular Diseases and Regenerative Angiogenesis Nutritional and Metabolic Bases of Cardiovascular Disease. 229-237. DOI: 10.1002/9781444318456.ch30  0.382
2010 De Nigris F, Crudele V, Giovane A, Casamassimi A, Giordano A, Garban HJ, Cacciatore F, Pentimalli F, Marquez-Garban DC, Petrillo A, Cito L, Sommese L, Fiore A, Petrillo M, Siani A, ... ... Ignarro LJ, et al. CXCR4/YY1 inhibition impairs VEGF network and angiogenesis during malignancy Proceedings of the National Academy of Sciences of the United States of America. 107: 14484-14489. PMID 20660740 DOI: 10.1073/Pnas.1008256107  0.4
2010 Meldrum DR, Gambone JC, Morris MA, Ignarro LJ. A multifaceted approach to maximize erectile function and vascular health Fertility and Sterility. 94: 2514-2520. PMID 20522326 DOI: 10.1016/J.Fertnstert.2010.04.026  0.422
2010 Balestrieri ML, Lu SJ, de Nigris F, Giovane A, Williams-Ignarro S, D'Armiento FP, Feng Q, Fiorito C, Testa G, Pastore L, Cacciatore F, Mancini FP, Servillo L, De Rosa G, Pagliarulo C, ... ... Ignarro LJ, et al. Therapeutic angiogenesis in diabetic apolipoprotein E-deficient mice using bone marrow cells, functional hemangioblasts and metabolic intervention. Atherosclerosis. 209: 403-14. PMID 19932479 DOI: 10.1016/J.Atherosclerosis.2009.10.022  0.396
2010 De Nigris F, Crudele V, Giovane A, Casamassimi A, Garban HJ, Marquez-Garban DC, Hayashi T, Ignarro LJ, Napoli C. Reply to Klar: Key role of YY1 in neoangiogenesis Proceedings of the National Academy of Sciences of the United States of America. 107: E191. DOI: 10.1073/Pnas.1011623108  0.375
2010 Napoli C, Crimi E, Williams-Ignarro S, Nigris Fd, Ignarro LJ. Nitric Oxide, Oxidative Stress, Immune Response and Critical Care Nitric Oxide. 755-772. DOI: 10.1016/B978-0-12-373866-0.00023-X  0.341
2010 Napoli C, Lerman LO, Balestrieri ML, Ignarro LJ. Nitric Oxide in Vascular Damage and Regeneration Nitric Oxide. 629-672. DOI: 10.1016/B978-0-12-373866-0.00020-4  0.388
2009 Napoli C, Ignarro LJ. Nitric oxide and pathogenic mechanisms involved in the development of vascular diseases Archives of Pharmacal Research. 32: 1103-1108. PMID 19727602 DOI: 10.1007/S12272-009-1801-1  0.462
2009 Ignarro LJ. Preface to this special journal issue on nitric oxide chemistry and biology Archives of Pharmacal Research. 32: 1099-1101. PMID 19727601 DOI: 10.1007/S12272-009-1800-2  0.46
2009 Strauch B, Herman C, Dabb R, Ignarro LJ, Pilla AA. Evidence-Based Use of Pulsed Electromagnetic Field Therapy in Clinical Plastic Surgery Aesthetic Surgery Journal. 29: 135-143. PMID 19371845 DOI: 10.1016/J.Asj.2009.02.001  0.314
2009 Crimi E, Ignarro LJ, Cacciatore F, Napoli C. Mechanisms by which exercise training benefits patients with heart failure Nature Reviews Cardiology. 6: 292-300. PMID 19352333 DOI: 10.1038/Nrcardio.2009.8  0.323
2009 Di Villa Bianca RDE, Sorrentino R, Maffia P, Mirone V, Imbimbo C, Fusco F, De Palma R, Ignarro LJ, Cirino G. Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation Proceedings of the National Academy of Sciences of the United States of America. 106: 4513-4518. PMID 19255435 DOI: 10.1073/Pnas.0807974105  0.409
2008 Napoli C, Bruzzese G, Ignarro LJ, Crimi E, de Nigris F, Williams-Ignarro S, Libardi S, Sommese L, Fiorito C, Mancini FP, Cacciatore F, Liguori A. Long-term treatment with sulfhydryl angiotensin-converting enzyme inhibition reduces carotid intima-media thickening and improves the nitric oxide/oxidative stress pathways in newly diagnosed patients with mild to moderate primary hypertension. American Heart Journal. 156: 1154.e1-8. PMID 19033012 DOI: 10.1016/J.Ahj.2008.09.006  0.456
2008 Salvatore P, Casamassimi A, Sommese L, Fiorito C, Ciccodicol A, Rossiello R, Avallone B, Grimaldi V, Costa V, Rienzo M, Colicchio R, Williams-Ignarro S, Pagliarulo C, Prudente ME, Abbondanza C, ... ... Ignarro LJ, et al. Detrimental effects of Bartonella henselae are counteracted by L-arginine and nitric oxide in human endothelial progenitor cells Proceedings of the National Academy of Sciences of the United States of America. 105: 9427-9432. PMID 18595894 DOI: 10.1073/Pnas.0803602105  0.452
2008 Ignarro L, Heber D, Henig YS, Bejar E. Herbalife nutritional products and liver injury revisited. Journal of Hepatology. 49: 291-293. PMID 18550201 DOI: 10.1016/J.Jhep.2008.05.005  0.313
2008 Ignarro LJ. Different pharmacological properties of two enantiomers in a unique β-blocker, nebivolol Cardiovascular Therapeutics. 26: 115-134. PMID 18485134 DOI: 10.1111/J.1527-3466.2008.00044.X  0.425
2008 de Nigris F, Mancini FP, Balestrieri ML, Byrns R, Fiorito C, Williams-Ignarro S, Palagiano A, Crimi E, Ignarro LJ, Napoli C. Therapeutic dose of nebivolol, a nitric oxide-releasing beta-blocker, reduces atherosclerosis in cholesterol-fed rabbits. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 19: 57-63. PMID 18435936 DOI: 10.1016/J.Niox.2008.03.004  0.439
2008 Napoli C, William-Ignarro S, Byrns R, Balestrieri ML, Crimi E, Farzati B, Mancini FP, de Nigris F, Matarazzo A, D'Amora M, Abbondanza C, Fiorito C, Giovane A, Florio A, Varricchio E, ... ... Ignarro LJ, et al. Therapeutic targeting of the stem cell niche in experimental hindlimb ischemia. Nature Clinical Practice. Cardiovascular Medicine. 5: 571-9. PMID 18414452 DOI: 10.1038/Ncpcardio1214  0.363
2008 Wei LH, Yang Y, Wu G, Ignarro LJ. IL-4 and IL-13 upregulate ornithine decarboxylase expression by PI3K and MAP kinase pathways in vascular smooth muscle cells American Journal of Physiology - Cell Physiology. 294: C1198-C1205. PMID 18367589 DOI: 10.1152/Ajpcell.00325.2007  0.368
2008 De Nigris F, Rossiello R, Schiano C, Arra C, Williams-Ignarro S, Barbieri A, Lanza A, Balestrieri A, Giuliano MT, Ignarro LJ, Napoli C. Deletion of Yin Yang 1 protein in osteosarcoma cells on cell invasion and CXCR4/angiogenesis and metastasis Cancer Research. 68: 1797-1808. PMID 18339860 DOI: 10.1158/0008-5472.Can-07-5582  0.383
2008 Bratasz A, Selvendiran K, Wasowicz T, Bobko A, Khramtsov VV, Ignarro LJ, Kuppusamy P. NCX-4040, a nitric oxide-releasing aspirin, sensitizes drug-resistant human ovarian xenograft tumors to cisplatin by depletion of cellular thiols. Journal of Translational Medicine. 6: 9. PMID 18302761 DOI: 10.1186/1479-5876-6-9  0.403
2008 Selvendiran K, Bratasz A, Tong L, Ignarro LJ, Kuppusamy P. NCX-4016, a nitro-derivative of aspirin, inhibits EGFR and STAT3 signaling and modulates Bcl-2 proteins in cisplatin-resistant human ovarian cancer cells and xenografts Cell Cycle. 7: 81-88. PMID 18196976 DOI: 10.4161/Cc.7.1.5103  0.389
2008 Liguori A, Fiorito C, Balestrieri ML, Crimi E, Bruzzese G, Williams-Ignarro S, D'Amora M, Sommese L, Grimaldi V, Minucci PB, Giovane A, Farzati B, Ignarro LJ, Napoli C. Functional impairment of hematopoietic progenitor cells in patients with coronary heart disease. European Journal of Haematology. 80: 258-64. PMID 18081701 DOI: 10.1111/J.1600-0609.2007.01007.X  0.37
2007 Crimi E, Ignarro LJ, Napoli C. Microcirculation and oxidative stress Free Radical Research. 41: 1364-1375. PMID 18075839 DOI: 10.1080/10715760701732830  0.449
2007 Nigris FD, Balestrieri ML, Williams-Ignarro S, D'Armiento FP, Lerman LO, Byrns R, Crimi E, Palagiano A, Fatigati G, Ignarro LJ, Napoli C. Therapeutic effects of autologous bone marrow cells and metabolic intervention in the ischemic hindlimb of spontaneously hypertensive rats involve reduced cell senescence and CXCR4/Akt/eNOS Pathways Journal of Cardiovascular Pharmacology. 50: 424-433. PMID 18049311 DOI: 10.1097/Fjc.0B013E31812564E4  0.456
2007 Napoli C, Balestrieri A, Ignarro LJ. Therapeutic approaches in vascular repair induced by adult bone marrow cells and circulating progenitor endothelial cells Current Pharmaceutical Design. 13: 3245-3251. PMID 18045174 DOI: 10.2174/138161207782341303  0.403
2007 Liguori A, D'Armiento FP, Palagiano A, Balestrieri ML, Williams-Ignarro S, de Nigris F, Lerman LO, D'Amora M, Rienzo M, Fiorito C, Ignarro LJ, Palinski W, Napoli C. Effect of gestational hypercholesterolaemia on omental vasoreactivity, placental enzyme activity and transplacental passage of normal and oxidised fatty acids. Bjog : An International Journal of Obstetrics and Gynaecology. 114: 1547-56. PMID 17903226 DOI: 10.1111/J.1471-0528.2007.01510.X  0.392
2007 Ignarro LJ. Heart mtNOS, a key mediator of oxidative injury in ischemia/reperfusion Journal of Molecular and Cellular Cardiology. 43: 409-410. PMID 17764688 DOI: 10.1016/J.Yjmcc.2007.07.053  0.41
2007 Parinandi NL, Sharma A, Eubank TD, Kaufman BF, Kutala VK, Marsh CB, Ignarro LJ, Kuppusamy P. Nitroaspirin (NCX-4016), an NO donor, is antiangiogenic through induction of loss of redox-dependent viability and cytoskeletal reorganization in endothelial cells Antioxidants and Redox Signaling. 9: 1837-1849. PMID 17760507 DOI: 10.1089/Ars.2007.1603  0.464
2007 Napoli C, Maione C, Schiano C, Fiorito C, Ignarro LJ. Bone marrow cell-mediated cardiovascular repair: potential of combined therapies Trends in Molecular Medicine. 13: 278-286. PMID 17574919 DOI: 10.1016/J.Molmed.2007.05.004  0.421
2007 de Nigris F, Balestrieri ML, Williams-Ignarro S, D'Armiento FP, Fiorito C, Ignarro LJ, Napoli C. The influence of pomegranate fruit extract in comparison to regular pomegranate juice and seed oil on nitric oxide and arterial function in obese Zucker rats Nitric Oxide - Biology and Chemistry. 17: 50-54. PMID 17553710 DOI: 10.1016/J.Niox.2007.04.005  0.422
2007 Bode-Böger SM, Scalera F, Ignarro LJ. The l-arginine paradox: Importance of the l-arginine/asymmetrical dimethylarginine ratio Pharmacology and Therapeutics. 114: 295-306. PMID 17482266 DOI: 10.1016/J.Pharmthera.2007.03.002  0.439
2007 Baker AH, Sica V, Work LM, Williams-Ignarro S, De Nigris F, Lerman LO, Casamassimi A, Lanza A, Schiano C, Rienzo M, Ignarro LJ, Napoli C. Brain protection using autologous bone marrow cell, metalloproteinase inhibitors, and metabolic treatment in cerebral ischemia Proceedings of the National Academy of Sciences of the United States of America. 104: 3597-3602. PMID 17360688 DOI: 10.1073/Pnas.0611112104  0.375
2007 Hayashi T, Juliet PAR, Miyazaki A, Ignarro LJ, Iguchi A. High glucose downregulates the number of caveolae in monocytes through oxidative stress from NADPH oxidase: Implications for atherosclerosis Biochimica Et Biophysica Acta - Molecular Basis of Disease. 1772: 364-372. PMID 17240121 DOI: 10.1016/J.Bbadis.2006.11.011  0.426
2007 Ohta F, Takagi T, Sato H, Ignarro LJ. Low-dose L-arginine administration increases microperfusion of hindlimb muscle without affecting blood pressure in rats Proceedings of the National Academy of Sciences of the United States of America. 104: 1407-1411. PMID 17229841 DOI: 10.1073/Pnas.0610207104  0.363
2007 Napoli C, Stanley WC, Ignarro LJ. Nutrition and cardiovascular disease: putting a pathogenic framework into focus. Cardiovascular Research. 73: 253-6. PMID 17161832 DOI: 10.1016/J.Cardiores.2006.11.032  0.355
2007 de Nigris F, Williams-Ignarro S, Sica V, Lerman LO, D'Armiento FP, Byrns RE, Casamassimi A, Carpentiero D, Schiano C, Sumi D, Fiorito C, Ignarro LJ, Napoli C. Effects of a Pomegranate Fruit Extract rich in punicalagin on oxidation-sensitive genes and eNOS activity at sites of perturbed shear stress and atherogenesis Cardiovascular Research. 73: 414-423. PMID 17014835 DOI: 10.1016/j.cardiores.2006.08.021  0.329
2007 Ignarro LJ, Balestrieri ML, Napoli C. Nutrition, physical activity, and cardiovascular disease: An update Cardiovascular Research. 73: 326-340. PMID 16945357 DOI: 10.1016/J.Cardiores.2006.06.030  0.409
2007 Osawa M, Hayashi T, Nomura H, Funami J, Miyazaki A, Ignarro LJ, Iguchi A. Nitric oxide (NO) is a new clinical biomarker of survival in the elderly patients and its efficacy might be nearly equal to albumin Nitric Oxide - Biology and Chemistry. 16: 157-163. PMID 16889997 DOI: 10.1016/J.Niox.2006.06.002  0.377
2007 de Nigris F, Williams-Ignarro S, Sica V, D'Armiento FP, Lerman LO, Byrns RE, Sica G, Fiorito C, Ignarro LJ, Napoli C. Therapeutic effects of concurrent autologous bone marrow cell infusion and metabolic intervention in ischemia-induced angiogenesis in the hypercholesterolemic mouse hindlimb International Journal of Cardiology. 117: 238-243. PMID 16875745 DOI: 10.1016/J.Ijcard.2006.05.020  0.445
2007 Napoli C, Ignarro LJ. Polymorphisms in endothelial nitric oxide synthase and carotid artery atherosclerosis Journal of Clinical Pathology. 60: 341-344. PMID 16837626 DOI: 10.1136/Jcp.2006.040550  0.505
2007 Olson SY, Marquez DC, Ignarro LJ, Economou JS, Garban HJ. B4. Nitric oxide suppresses the expression of the tolerogenic transcription factor FOXP3 in tumor cells Nitric Oxide. 17: 17. DOI: 10.1016/J.Niox.2007.09.037  0.423
2006 Sica V, Williams-Ignarro S, De Nigris F, D'Armiento FP, Lerman LO, Balestrieri ML, Maione C, Palagiano A, Rossiello L, Ignarro LJ, Napoli C. Autologous bone marrow cell therapy and metabolic intervention in ischemia-induced angiogenesis in the diabetic mouse hindlimb Cell Cycle. 5: 2903-2908. PMID 17172874 DOI: 10.4161/Cc.5.24.3568  0.425
2006 Hayashi T, Matsui-Hirai H, Miyazaki-Akita A, Fukatsu A, Funami J, Ding QF, Kamalanathan S, Nation Y, Ignarro LJ, Iguchi A. Endothelial cellular senescence is inhibited by nitric oxide: Implications in atherosclerosis associated with menopause and diabetes Proceedings of the National Academy of Sciences of the United States of America. 103: 17018-17023. PMID 17075048 DOI: 10.1073/Pnas.0607873103  0.477
2006 Crimi E, Sica V, Slutsky AS, Zhang H, Williams-Ignarro S, Ignarro LJ, Napoli C. Role of oxidative stress in experimental sepsis and multisystem organ dysfunction Free Radical Research. 40: 665-672. PMID 16983993 DOI: 10.1080/10715760600669612  0.424
2006 Rodríguez LV, Alfonso Z, Zhang R, Leung J, Wu B, Ignarro LJ. Clonogenic multipotent stem cells in human adipose tissue differentiate into functional smooth muscle cells Proceedings of the National Academy of Sciences of the United States of America. 103: 12167-12172. PMID 16880387 DOI: 10.1073/Pnas.0604850103  0.373
2006 Buga GM, Frank JS, Mottino GA, Hendizadeh M, Hakhamian A, Tillisch JH, Reddy ST, Navab M, Anantharamaiah GM, Ignarro LJ, Fogelman AM. D-4F decreases brain arteriole inflammation and improves cognitive performance in LDL receptor-null mice on a Western diet Journal of Lipid Research. 47: 2148-2160. PMID 16835442 DOI: 10.1194/Jlr.M600214-Jlr200  0.341
2006 Pantuck AJ, Leppert JT, Zomorodian N, Aronson W, Hong J, Barnard RJ, Seeram N, Liker H, Wang H, Elashoff R, Heber D, Aviram M, Ignarro L, Belldegrun A. Phase II study of pomegranate juice for men with rising prostate-specific antigen following surgery or radiation for prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 4018-26. PMID 16818701 DOI: 10.1158/1078-0432.Ccr-05-2290  0.312
2006 Napoli C, Williams-Ignarro S, De Nigris F, Lerman LO, D'Armiento FP, Crimi E, Byrns RE, Casamassimi A, Lanza A, Gombos F, Sica V, Ignarro LJ. Physical training and metabolic supplementation reduce spontaneous atherosclerotic plaque rupture and prolong survival in hypercholesterolemic mice Proceedings of the National Academy of Sciences of the United States of America. 103: 10479-10484. PMID 16801544 DOI: 10.1073/Pnas.0602774103  0.378
2006 Napoli C, de Nigris F, Williams-Ignarro S, Pignalosa O, Sica V, Ignarro LJ. Nitric oxide and atherosclerosis: An update Nitric Oxide - Biology and Chemistry. 15: 265-279. PMID 16684613 DOI: 10.1016/J.Niox.2006.03.011  0.515
2006 Pryor WA, Houk KN, Foote CS, Fukuto JM, Ignarro LJ, Squadrito GL, Davies KJ. Free radical biology and medicine: it's a gas, man! American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 291: R491-511. PMID 16627692 DOI: 10.1152/Ajpregu.00614.2005  0.426
2006 Ignarro LJ, Byrns RE, Sumi D, de Nigris F, Napoli C. Pomegranate juice protects nitric oxide against oxidative destruction and enhances the biological actions of nitric oxide Nitric Oxide - Biology and Chemistry. 15: 93-102. PMID 16626982 DOI: 10.1016/J.Niox.2006.03.001  0.537
2006 Bratasz A, Weir NM, Parinandi NL, Zweier JL, Sridhar R, Ignarro LJ, Kuppusamy P. Reversal to cisplatin sensitivity in recurrent human ovarian cancer cells by NCX-4016, a nitro derivative of aspirin Proceedings of the National Academy of Sciences of the United States of America. 103: 3914-3919. PMID 16497833 DOI: 10.1073/Pnas.0511250103  0.38
2006 Matteo M, Cicinelli E, Baldini D, Cho YS, Ignarro LJ, Vitarelli A, Boffoli D, Greco P. Influence of human menopausal gonadotrophin treatment on testicular blood flow and on seminal plasma nitric oxide levels in infertile males International Journal of Andrology. 29: 441-445. PMID 16487405 DOI: 10.1111/J.1365-2605.2005.00627.X  0.392
2006 Crimi E, Sica V, Williams-Ignarro S, Zhang H, Slutsky AS, Ignarro LJ, Napoli C. The role of oxidative stress in adult critical care Free Radical Biology and Medicine. 40: 398-406. PMID 16443154 DOI: 10.1016/J.Freeradbiomed.2005.10.054  0.433
2006 de Nigris F, Williams-Ignarro S, Botti C, Sica V, Ignarro LJ, Napoli C. Pomegranate juice reduces oxidized low-density lipoprotein downregulation of endothelial nitric oxide synthase in human coronary endothelial cells Nitric Oxide - Biology and Chemistry. 15: 259-263. PMID 16413211 DOI: 10.1016/J.Niox.2005.12.004  0.506
2006 Miller TW, Franco NE, Hobbs AJ, Ignarro LJ, Fukuto JM. P067. Effect of changing redox status on the activation of soluble guanylate cyclase by nitrogen oxides Nitric Oxide. 14: 38. DOI: 10.1016/J.Niox.2006.04.129  0.453
2006 Ignarro LJ, Napoli C. Overview of the role of nitric oxide as a signaling molecule in the cardiovascular system Medicina Dello Sport. 59: 425-426.  0.358
2005 Napoli C, Williams-Ignarro S, de Nigris F, de Rosa G, Lerman LO, Farzati B, Matarazzo A, Sica G, Botti C, Fiore A, Byrns RE, Sumi D, Sica V, Ignarro LJ. Beneficial effects of concurrent autologous bone marrow cell therapy and metabolic intervention in ischemia-induced angiogenesis in the mouse hindlimb. Proceedings of the National Academy of Sciences of the United States of America. 102: 17202-6. PMID 16286655 DOI: 10.1073/Pnas.0508534102  0.442
2005 Hayashi T, Juliet PAR, Matsui-Hirai H, Miyasaki A, Fukatsu A, Funami J, Iguchi A, Ignarro LJ. L-citrulline and L-arginine supplementation retards the progression of high-cholesterol-diet-induced atherosclerosis in rabbits Proceedings of the National Academy of Sciences of the United States of America. 102: 13681-13686. PMID 16157883 DOI: 10.1073/Pnas.0506595102  0.454
2005 Ignarro LJ. Nitric oxide. Current Topics in Medicinal Chemistry. 5: 595. PMID 16101421  0.39
2005 De Nigris F, Williams-Ignarro S, Lerman LO, Crimi E, Botti C, Mansueto G, D'Armiento FP, De Rosa G, Sica V, Ignarro LJ, Napoli C. Beneficial effects of pomegranate juice on oxidation-sensitive genes and endothelial nitric oxide synthase activity at sites of perturbed shear stress Proceedings of the National Academy of Sciences of the United States of America. 102: 4896-4901. PMID 15781875 DOI: 10.1073/pnas.0500998102  0.373
2005 Garbán HJ, Márquez-Garbán DC, Pietras RJ, Ignarro LJ. Rapid nitric oxide-mediated S-nitrosylation of estrogen receptor: Regulation of estrogen-dependent gene transcription Proceedings of the National Academy of Sciences of the United States of America. 102: 2632-2636. PMID 15699347 DOI: 10.1073/Pnas.0409854102  0.391
2005 Sumi D, Ignarro LJ. Sp1 transcription factor expression is regulated by estrogen-related receptor α1 Biochemical and Biophysical Research Communications. 328: 165-172. PMID 15670765 DOI: 10.1016/J.Bbrc.2004.12.165  0.355
2005 Ignarro LJ, Napoli C. Novel features of nitric oxide, endothelial nitric oxide synthase, and atherosclerosis Current Diabetes Reports. 5: 17-23. PMID 15663912 DOI: 10.1007/S11892-005-0062-8  0.518
2005 Bucci M, Roviezzo F, Posadas I, Yu J, Parente L, Sessa WC, Ignarro LJ, Cirino G. Endothelial nitric oxide synthase activation is critical for vascular leakage during acute inflammation in vivo Proceedings of the National Academy of Sciences of the United States of America. 102: 904-908. PMID 15640348 DOI: 10.1073/Pnas.0408906102  0.457
2005 Ignarro LJ. Editorial Current Topics in Medicinal Chemistry. 5: 595. DOI: 10.2174/1568026054679371  0.159
2005 Buret A, Cordeiro RSB, Ignarro LJ, Wallace JL. Memórias do Instituto Oswaldo Cruz: Foreword Memorias Do Instituto Oswaldo Cruz. 100: i.  0.172
2004 Ignarro LJ. Experimental evidences of nitric oxide-dependent vasodilatory activity of nebivolol, a third-generation β-blocker Blood Pressure, Supplement. 13: 2-16. PMID 15587107 DOI: 10.1080/08038020410016557  0.513
2004 Olcott AP, Tocco G, Tian J, Zekzer D, Fukuto J, Ignarro L, Kaufman DL. A salen-manganese catalytic free radical scavenger inhibits type 1 diabetes and islet allograft rejection. Diabetes. 53: 2574-80. PMID 15448086 DOI: 10.2337/Diabetes.53.10.2574  0.429
2004 Hayashi T, Rani P JA, Fukatsu A, Matsui-Hirai H, Osawa M, Miyazaki A, Tsunekawa T, Kano-Hayashi H, Iguchi A, Sumi D, Ignarro LJ. A new HMG-CoA reductase inhibitor, pitavastatin remarkably retards the progression of high cholesterol induced atherosclerosis in rabbits Atherosclerosis. 176: 255-263. PMID 15380447 DOI: 10.1016/J.Atherosclerosis.2003.12.034  0.391
2004 Juliet PAR, Hayashi T, Daigo S, Matsui-Hirai H, Miyazaki A, Fukatsu A, Funami J, Iguchi A, Ignarro LJ. Combined effect of testosterone and apocynin on nitric oxide and superoxide production in PMA-differentiated THP-1 cells Biochimica Et Biophysica Acta - Molecular Cell Research. 1693: 185-191. PMID 15363632 DOI: 10.1016/J.Bbamcr.2004.08.002  0.476
2004 Sumi D, Ignarro LJ. Regulation of inducible nitric oxide synthase expression in advanced glycation end product-stimulated RAW 264.7 cells: The role of heme oxygenase-1 and endogenous nitric oxide Diabetes. 53: 1841-1850. PMID 15220209 DOI: 10.2337/Diabetes.53.7.1841  0.461
2004 Napoli C, Sica V, de Nigris F, Pignalosa O, Condorelli M, Ignarro LJ, Liguori A. Sulfhydryl angiotensin-converting enzyme inhibition induces sustained reduction of systemic oxidative stress and improves the nitric oxide pathway in patients with essential hypertension. American Heart Journal. 148: e5. PMID 15215814 DOI: 10.1016/J.Ahj.2004.03.025  0.496
2004 Ignarro LJ, Napoli C. Novel features of nitric oxide, endothelial nitric oxide synthase, and atherosclerosis. Current Atherosclerosis Reports. 6: 281-7. PMID 15191702 DOI: 10.1007/S11883-004-0059-9  0.518
2004 Ongini E, Impagnatiello F, Bonazzi A, Guzzetta M, Govoni M, Monopoli A, Del Soldato P, Ignarro LJ. Nitric oxide (NO)-releasing statin derivatives, a class of drugs showing enhanced antiproliferative and antiinflammatory properties Proceedings of the National Academy of Sciences of the United States of America. 101: 8497-8502. PMID 15173604 DOI: 10.1073/Pnas.0401996101  0.48
2004 Napoli C, Williams-Ignarro S, De Nigris F, Lerman LO, Rossi L, Guarino C, Mansueto G, Di Tuoro F, Pignalosa O, De Rosa G, Sica V, Ignarro LJ. Long-term combined beneficial effects of physical training and metabolic treatment on atherosclerosis in hypercholesterolemic mice Proceedings of the National Academy of Sciences of the United States of America. 101: 8797-8802. PMID 15169957 DOI: 10.1073/Pnas.0402734101  0.406
2004 Garbán HJ, Buga GM, Ignarro LJ. Estrogen Receptor-Mediated Vascular Responsiveness to Nebivolol: A Novel Endothelium-Related Mechanism of Therapeutic Vasorelaxation Journal of Cardiovascular Pharmacology. 43: 638-644. PMID 15071350 DOI: 10.1097/00005344-200405000-00005  0.431
2004 Takeuchi K, Watanabe H, Tran QK, Ozeki M, Sumi D, Hayashi T, Iguchi A, Ignarro LJ, Ohashi K, Hayashi H. Nitric oxide: Inhibitory effects on endothelial cell calcium signaling, prostaglandin I2 production and nitric oxide synthase expression Cardiovascular Research. 62: 194-201. PMID 15023566 DOI: 10.1016/J.Cardiores.2003.12.028  0.515
2004 Hayashi T, Sumi D, Juliet PAR, Matsui-Hirai H, Asai-Tanaka Y, Kano H, Fukatsu A, Tsunekawa T, Miyazaki A, Iguchi A, Ignarro LJ. Gene transfer of endothelial NO synthase, but not eNOS plus inducible NOS, regressed atherosclerosis in rabbits Cardiovascular Research. 61: 339-351. PMID 14736551 DOI: 10.1016/J.Cardiores.2003.09.027  0.397
2004 Nigris FD, Lerman LO, Ignarro SW, Sica G, Lerman A, Palinski W, Ignarro LJ, Napoli C. Erratum: Beneficial effects of antioxidants and L-arginine on oxidation-sensitive gene expression and endothelial NO synthase activity at sites of disturbed shear stress (Proceedings of the National Academy of Sciences of the United States of America (February 4, 2003) 100, 3 (1420-1425)) Proceedings of the National Academy of Sciences of the United States of America. 101. DOI: 10.1073/Pnas.0409060101  0.449
2004 Napoli C, Williams-Ignarro S, Nigris FD, Lerman LO, Rossi L, Guarino C, Mansueto G, Tuoro FD, Pignalosa O, Rosa GD, Sica V, Ignarro LJ. Erratum: Long-term combined beneficial effects of physical training and metabolic treatment on atherosclerosis in hypercholesterolemic mice (Proceedings of the National Academy of Sciences of the United States of America (June 8, 2004) 101, 23 (8797-8802)) Proceedings of the National Academy of Sciences of the United States of America. 101. DOI: 10.1073/Pnas.0409058101  0.317
2004 Mirone V, Cirino G, Imbimbo C, Palmieri A, Longo N, Fusco F, Ignarro LJ. 10 Involvement of beta3-adrenergic receptor activation via cyclic GMP in human corpus cavernosum function European Urology Supplements. 3: 5. DOI: 10.1016/S1569-9056(04)90012-7  0.36
2003 Castellá M, Buckberg GD, Saleh S, Tan Z, Ignarro LJ. A new role for cardioplegic buffering: Should acidosis or calcium accumulation be counteracted to salvage jeopardized hearts? Journal of Thoracic and Cardiovascular Surgery. 126: 1442-1448. PMID 14666017 DOI: 10.1016/S0022-5223(03)00599-3  0.363
2003 Sumi D, Ignarro LJ. Estrogen-related receptor α1 up-regulates endothelial nitric oxide synthase expression Proceedings of the National Academy of Sciences of the United States of America. 100: 14451-14456. PMID 14610283 DOI: 10.1073/Pnas.2235590100  0.439
2003 Juliet PA, Hayashi T, Iguchi A, Ignarro LJ. Concomitant production of nitric oxide and superoxide in human macrophages. Biochemical and Biophysical Research Communications. 310: 367-70. PMID 14521919 DOI: 10.1016/J.Bbrc.2003.08.133  0.486
2003 de Nigris F, Lerman A, Ignarro LJ, Williams-Ignarro S, Sica V, Baker AH, Lerman LO, Geng YJ, Napoli C. Oxidation-sensitive mechanisms, vascular apoptosis and atherosclerosis. Trends in Molecular Medicine. 9: 351-9. PMID 12928037 DOI: 10.1016/S1471-4914(03)00139-4  0.486
2003 Jacobs AT, Ignarro LJ. Cell density-enhanced expression of inducible nitric oxide synthase in murine macrophages mediated by interferon-beta. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 8: 222-30. PMID 12895431 DOI: 10.1016/S1089-8603(03)00027-2  0.712
2003 Sumi D, Hayashi T, Matsui-Hirai H, Jacobs AT, Ignarro LJ, Iguchi A. 17beta-estradiol inhibits NADPH oxidase activity through the regulation of p47phox mRNA and protein expression in THP-1 cells. Biochimica Et Biophysica Acta. 1640: 113-8. PMID 12729920 DOI: 10.1016/S0167-4889(03)00026-0  0.705
2003 Cirino G, Sorrentino R, di Villa Bianca Rd, Popolo A, Palmieri A, Imbimbo C, Fusco F, Longo N, Tajana G, Ignarro LJ, Mirone V. Involvement of beta 3-adrenergic receptor activation via cyclic GMP- but not NO-dependent mechanisms in human corpus cavernosum function. Proceedings of the National Academy of Sciences of the United States of America. 100: 5531-6. PMID 12707413 DOI: 10.1073/Pnas.0931347100  0.368
2003 Allen BS, Veluz JS, Buckberg GD, Aeberhard E, Ignarro LJ. Deep hypothermic circulatory arrest and global reperfusion injury: avoidance by making a pump prime reperfusate--a new concept. The Journal of Thoracic and Cardiovascular Surgery. 125: 625-32. PMID 12658205 DOI: 10.1067/Mtc.2003.96  0.326
2003 Davis MR, Ortegon DP, Kerby JD, Ignarro LJ, Kashyap VS. Endothelial dysfunction after arterial thrombosis is ameliorated by L-arginine in combination with thrombolysis. Journal of Vascular and Interventional Radiology : Jvir. 14: 233-9. PMID 12582192 DOI: 10.1097/01.Rvi.0000058326.82956.B8  0.41
2003 Napoli C, Ignarro LJ. Nitric Oxide-Releasing Drugs Annual Review of Pharmacology and Toxicology. 43: 97-123. PMID 12540742 DOI: 10.1146/Annurev.Pharmtox.43.100901.140226  0.405
2003 Azizzadeh B, Buga GM, Berke GS, Larian B, Ignarro LJ, Blackwell KE. Inhibitors of nitric oxide promote microvascular thrombosis. Archives of Facial Plastic Surgery. 5: 31-5. PMID 12533135 DOI: 10.1001/Archfaci.5.1.31  0.43
2003 de Nigris F, Lerman LO, Ignarro SW, Sica G, Lerman A, Palinski W, Ignarro LJ, Napoli C. Beneficial effects of antioxidants and L-arginine on oxidation-sensitive gene expression and endothelial NO synthase activity at sites of disturbed shear stress. Proceedings of the National Academy of Sciences of the United States of America. 100: 1420-5. PMID 12525696 DOI: 10.1073/Pnas.0237367100  0.468
2003 Jacobs AT, Ignarro LJ. Nuclear factor-kappa B and mitogen-activated protein kinases mediate nitric oxide-enhanced transcriptional expression of interferon-beta. The Journal of Biological Chemistry. 278: 8018-27. PMID 12500976 DOI: 10.1074/Jbc.M211642200  0.696
2002 Ignarro LJ. Wei Lun Visiting Professorial Lecture: Nitric oxide in the regulation of vascular function: an historical overview. Journal of Cardiac Surgery. 17: 301-6. PMID 12546077 DOI: 10.1111/J.1540-8191.2001.Tb01148.X  0.486
2002 Ignarro LJ. Nitric oxide as a unique signaling molecule in the vascular system: a historical overview. Journal of Physiology and Pharmacology : An Official Journal of the Polish Physiological Society. 53: 503-14. PMID 12512688  0.343
2002 Castellá M, Buckberg GD, Tan Z, Ignarro LJ. Myocyte and endothelial effects of preconditioning the jeopardized heart by inhibiting Na/H exchange. The Journal of Thoracic and Cardiovascular Surgery. 124: 1113-21. PMID 12447176 DOI: 10.1067/Mtc.2002.125485  0.379
2002 Fiorucci S, Antonelli E, Distrutti E, Del Soldato P, Flower RJ, Clark MJ, Morelli A, Perretti M, Ignarro LJ. NCX-1015, a nitric-oxide derivative of prednisolone, enhances regulatory T cells in the lamina propria and protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis in mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 15770-5. PMID 12427966 DOI: 10.1073/Pnas.232583599  0.454
2002 Napoli C, Lerman LO, de Nigris F, Loscalzo J, Ignarro LJ. Glycoxidized low-density lipoprotein downregulates endothelial nitricoxide synthase in human coronary cells. Journal of the American College of Cardiology. 40: 1515-22. PMID 12392844 DOI: 10.1016/S0735-1097(02)02306-9  0.458
2002 Ribas A, Amarnani SN, Buga GM, Butterfield LH, Dissette VB, McBride WH, Glaspy JA, Ignarro LJ, Economou JS. Immunosuppressive effects of interleukin-12 coexpression in melanoma antigen gene-modified dendritic cell vaccines. Cancer Gene Therapy. 9: 875-83. PMID 12386826 DOI: 10.1038/Sj.Cgt.7700512  0.354
2002 Ignarro LJ, Sisodia M, Trinh K, Bedrood S, Wu G, Wei LH, Buga GM. Nebivolol inhibits vascular smooth muscle cell proliferation by mechanisms involving nitric oxide but not cyclic GMP. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 7: 83-90. PMID 12223177 DOI: 10.1016/S1089-8603(02)00113-1  0.478
2002 Ignarro LJ, Byrns RE, Trinh K, Sisodia M, Buga GM. Nebivolol: a selective beta(1)-adrenergic receptor antagonist that relaxes vascular smooth muscle by nitric oxide- and cyclic GMP-dependent mechanisms. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 7: 75-82. PMID 12223176 DOI: 10.1016/S1089-8603(02)00112-X  0.489
2002 Cicinelli E, Ignarro LJ, Galantino P, Pinto V, Barba B, Schonauer S. Effects of tibolone on plasma levels of nitric oxide in postmenopausal women. Fertility and Sterility. 78: 464-8. PMID 12215318 DOI: 10.1016/S0015-0282(02)03295-8  0.414
2002 Wallace JL, Ignarro LJ, Fiorucci S. Potential cardioprotective actions of no-releasing aspirin. Nature Reviews. Drug Discovery. 1: 375-82. PMID 12120413 DOI: 10.1038/Nrd794  0.398
2002 Ignarro LJ. After 130 years, the molecular mechanism of action of nitroglycerin is revealed. Proceedings of the National Academy of Sciences of the United States of America. 99: 7816-7. PMID 12060725 DOI: 10.1073/Pnas.132271799  0.431
2002 Napoli C, Aldini G, Wallace JL, de Nigris F, Maffei R, Abete P, Bonaduce D, Condorelli G, Rengo F, Sica V, D'Armiento FP, Mignogna C, de Rosa G, Condorelli M, Lerman LO, ... Ignarro LJ, et al. Efficacy and age-related effects of nitric oxide-releasing aspirin on experimental restenosis. Proceedings of the National Academy of Sciences of the United States of America. 99: 1689-94. PMID 11818533 DOI: 10.1073/Pnas.022639399  0.42
2002 Ignarro LJ, Napoli C, Loscalzo J. Nitric oxide donors and cardiovascular agents modulating the bioactivity of nitric oxide: An overview Circulation Research. 90: 21-28. PMID 11786514 DOI: 10.1161/Hh0102.102330  0.455
2001 Azizzadeh B, Yip HT, Blackwell KE, Horvath S, Calcaterra TC, Buga GM, Ignarro LJ, Wang MB. Nitric oxide improves cisplatin cytotoxicity in head and neck squamous cell carcinoma. The Laryngoscope. 111: 1896-900. PMID 11801965 DOI: 10.1097/00005537-200111000-00004  0.402
2001 Jacobs AT, Ignarro LJ. Lipopolysaccharide-induced expression of interferon-beta mediates the timing of inducible nitric-oxide synthase induction in RAW 264.7 macrophages. The Journal of Biological Chemistry. 276: 47950-7. PMID 11602590 DOI: 10.1074/Jbc.M106639200  0.701
2001 Bauer PM, Buga GM, Ignarro LJ. Role of p42/p44 mitogen-activated-protein kinase and p21waf1/cip1 in the regulation of vascular smooth muscle cell proliferation by nitric oxide. Proceedings of the National Academy of Sciences of the United States of America. 98: 12802-7. PMID 11592976 DOI: 10.1073/Pnas.211443198  0.695
2001 Kashyap MVS, Reil TD, Moore WS, Hoang TX, Gelabert HA, Byrns RE, Ignarro LJ, Freischlag JA. Acute arterial thrombosis causes endothelial dysfunction: A new paradigm for thrombolytic therapy Journal of Vascular Surgery. 34: 323-329. PMID 11496286 DOI: 10.1067/Mva.2001.115004  0.401
2001 Wei LH, Wu G, Morris SM, Ignarro LJ. Elevated arginase I expression in rat aortic smooth muscle cells increases cell proliferation Proceedings of the National Academy of Sciences of the United States of America. 98: 9260-9264. PMID 11470919 DOI: 10.1073/Pnas.161294898  0.448
2001 Bauer PM, Buga GM, Fukuto JM, Pegg AE, Ignarro LJ. Nitric oxide inhibits ornithine decarboxylase via S-nitrosylation of cysteine 360 in the active site of the enzyme. The Journal of Biological Chemistry. 276: 34458-64. PMID 11461922 DOI: 10.1074/Jbc.M105219200  0.72
2001 Ma L, Elliott SN, Cirino G, Buret A, Ignarro LJ, Wallace JL. Platelets modulate gastric ulcer healing: role of endostatin and vascular endothelial growth factor release. Proceedings of the National Academy of Sciences of the United States of America. 98: 6470-5. PMID 11353854 DOI: 10.1073/Pnas.111150798  0.375
2001 Napoli C, Ignarro LJ. Nitric Oxide and Atherosclerosis Nitric Oxide. 5: 88-97. PMID 11292358 DOI: 10.1006/Niox.2001.0337  0.508
2001 Ignarro LJ, Buga GM, Wei LH, Bauer PM, Wu G, del Soldato P. Role of the arginine-nitric oxide pathway in the regulation of vascular smooth muscle cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 98: 4202-8. PMID 11259671 DOI: 10.1073/Pnas.071054698  0.736
2001 Napoli C, Cirino G, Del Soldato P, Sorrentino R, Sica V, Condorelli M, Pinto A, Ignarro LJ. Effects of nitric oxide-releasing aspirin versus aspirin on restenosis in hypercholesterolemic mice Proceedings of the National Academy of Sciences of the United States of America. 98: 2860-2864. PMID 11226331 DOI: 10.1073/pnas.041602898  0.367
2001 Fiorucci S, Mencarelli A, Palazzetti B, Del Soldato P, Morelli A, Ignarro LJ. An NO derivative of ursodeoxycholic acid protects against Fas-mediated liver injury by inhibiting caspase activity Proceedings of the National Academy of Sciences of the United States of America. 98: 2652-2657. PMID 11226294 DOI: 10.1073/Pnas.041603898  0.403
2001 Jayachandran M, Hayashi T, Sumi D, Thakur NK, Kano H, Ignarro LJ, Iguchi A. Up-regulation of endothelial nitric oxide synthase through beta(2)-adrenergic receptor--the role of a beta-blocker with NO-releasing action. Biochemical and Biophysical Research Communications. 280: 589-94. PMID 11162560 DOI: 10.1006/Bbrc.2000.4177  0.4
2000 Shah S, Hobbs A, Singh R, Cuevas J, Ignarro LJ, Chaudhuri G. Gastrointestinal motility during pregnancy: Role of nitrergic component of NANC nerves American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 279: R1478-R1485. PMID 11004018 DOI: 10.1152/Ajpregu.2000.279.4.R1478  0.396
2000 Ignarro LJ. The unique role of nitric oxide as a signaling molecule in the cardiovascular system Italian Heart Journal : Official Journal of the Italian Federation of Cardiology. 1: S28-29. PMID 11003016  0.358
2000 Bivalacqua TJ, Champion HC, Mehta YS, Abdel-Mageed AB, Sikka SC, Ignarro LJ, Kadowitz PJ, Hellstrom WJ. Adenoviral gene transfer of endothelial nitric oxide synthase (eNOS) to the penis improves age-related erectile dysfunction in the rat. International Journal of Impotence Research. 12: S8-17. PMID 11002394 DOI: 10.1038/Sj.Ijir.3900556  0.41
2000 Wei LH, Jacobs AT, Morris SM, Ignarro LJ. IL-4 and IL-13 upregulate arginase I expression by cAMP and JAK/STAT6 pathways in vascular smooth muscle cells. American Journal of Physiology. Cell Physiology. 279: C248-56. PMID 10898736 DOI: 10.1152/Ajpcell.2000.279.1.C248  0.678
2000 Napoli C, Cicala C, Wallace JL, de Nigris F, Santagada V, Caliendo G, Franconi F, Ignarro LJ, Cirino G. Protease-activated receptor-2 modulates myocardial ischemia-reperfusion injury in the rat heart. Proceedings of the National Academy of Sciences of the United States of America. 97: 3678-83. PMID 10737808 DOI: 10.1073/Pnas.97.7.3678  0.424
2000 Honold J, Pusser NL, Nathan L, Chaudhuri G, Ignarro LJ, Sherman MP. Production and excretion of nitrate by human newborn infants: Neonates are not little adults Nitric Oxide - Biology and Chemistry. 4: 35-46. PMID 10733871 DOI: 10.1006/Niox.1999.0267  0.386
2000 Wei LH, Morris SM, Cederbaum SD, Mori M, Ignarro LJ. Induction of arginase II in human Caco-2 tumor cells by cyclic AMP Archives of Biochemistry and Biophysics. 374: 255-260. PMID 10666305 DOI: 10.1006/Abbi.1999.1563  0.419
2000 Ignarro LJ, Jacobs A. Chapter 1 Nitric oxide synthase and the production of nitric oxide Handbook of Chemical Neuroanatomy. 17: 1-17. DOI: 10.1016/S0924-8196(00)80055-X  0.71
1999 Ignarro LJ. Nitric oxide: A unique endogenous signaling molecule in vascular biology Bioscience Reports. 19: 51-71. PMID 10888468 DOI: 10.1023/A:1020150124721  0.468
1999 Ignarro LJ, Cirino G, Casini A, Napoli C. Nitric oxide as a signaling molecule in the vascular system: An overview Journal of Cardiovascular Pharmacology. 34: 879-886. PMID 10598133 DOI: 10.1097/00005344-199912000-00016  0.458
1999 Cicinelli E, Ignarro LJ, Schonauer LM, Matteo MG, Galantino P, Falco N. Different plasma levels of nitric oxide in arterial and venous blood Clinical Physiology. 19: 440-442. PMID 10516896 DOI: 10.1046/J.1365-2281.1999.00200.X  0.447
1999 Champion HC, Bivalacqua TJ, Hyman AL, Ignarro LJ, Hellstrom WJ, Kadowitz PJ. Gene transfer of endothelial nitric oxide synthase to the penis augments erectile responses in the aged rat. Proceedings of the National Academy of Sciences of the United States of America. 96: 11648-52. PMID 10500231 DOI: 10.1073/Pnas.96.20.11648  0.479
1999 Bauer PM, Fukuto JM, Buga GM, Pegg AE, Ignarro LJ. Nitric oxide inhibits ornithine decarboxylase by S-nitrosylation. Biochemical and Biophysical Research Communications. 262: 355-8. PMID 10462479 DOI: 10.1006/Bbrc.1999.1210  0.722
1999 Ma SX, Ignarro LJ, Byrns R, Li XY. Increased nitric oxide concentrations in posterior hypothalamus and central sympathetic function on nitrate tolerance following subcutaneous nitroglycerin Nitric Oxide - Biology and Chemistry. 3: 153-161. PMID 10369185 DOI: 10.1006/Niox.1999.0218  0.418
1999 Cicinelli E, Ignarro LJ, Matteo MG, Galantino P, Schonauer LM, Falco N. Effects of estrogen replacement therapy on plasma levels of nitric oxide in postmenopausal women American Journal of Obstetrics and Gynecology. 180: 334-339. PMID 9988796 DOI: 10.1016/S0002-9378(99)70209-7  0.403
1999 Ignarro LJ. Nitric oxide: A unique endogenous signaling molecule in vascular biology (Nobel lecture) Angewandte Chemie - International Edition. 38: 1882-1892. DOI: 10.1002/(Sici)1521-3773(19990712)38:13/14<1882::Aid-Anie1882>3.0.Co;2-V  0.505
1999 Ignarro LJ. Stickstoffmonoxid: ein einzigartiges endogenes Signalmolekül in der Gefäßbiologie (Nobel‐Vortrag) Angewandte Chemie. 111: 2002-2013. DOI: 10.1002/(Sici)1521-3757(19990712)111:13/14<2002::Aid-Ange2002>3.0.Co;2-Q  0.312
1999 Gonzalez-Cadavid NF, Ignarro LJ, Rajfer J. Nitric oxide and the cyclic GMP system in the penis Molecular Urology. 3: 51-59.  0.399
1998 Gaston B, Fry E, Sears S, Heroman WM, Ignarro L, Stamler JS. Umbilical arterial S-nitrosothiols in stressed newborns: Role in perinatal circulatory transition Biochemical and Biophysical Research Communications. 253: 899-901. PMID 9918827 DOI: 10.1006/Bbrc.1998.9865  0.37
1998 Buga GM, Wei LH, Bauer PM, Fukuto JM, Ignarro LJ. NG-hydroxy-L-arginine and nitric oxide inhibit Caco-2 tumor cell proliferation by distinct mechanisms. The American Journal of Physiology. 275: R1256-64. PMID 9756558 DOI: 10.1152/Ajpregu.1998.275.4.R1256  0.726
1998 Wei LH, Arabolos N, Ignarro LJ. Certain S-substituted isothioureas not only inhibit NO synthase catalytic activity but also decrease translation and stability of inducible NO synthase protein Nitric Oxide - Biology and Chemistry. 2: 155-164. PMID 9731633 DOI: 10.1006/Niox.1998.0171  0.434
1998 Ding M, Zhang M, Wong JL, Rogers NE, Ignarro LJ, Voskuhl RR. Antisense knockdown of inducible nitric oxide synthase inhibits induction of experimental autoimmune encephalomyelitis in SJL/J mice. Journal of Immunology (Baltimore, Md. : 1950). 160: 2560-4. PMID 9510151  0.394
1998 Cicinelli E, Ignarro LJ, Schönauer LM, Matteo MG, Galantino P, Balzano G. Effects of short-term transdermal estradiol administration on plasma levels of nitric oxide postmenopausal women Fertility and Sterility. 69: 58-61. PMID 9457933 DOI: 10.1016/S0015-0282(97)00424-X  0.405
1998 Lancaster JR, Ignarro LJ. Free Radical Biology and Medicine: Introduction Free Radical Biology and Medicine. 25: 384. DOI: 10.1016/S0891-5849(98)00122-1  0.22
1998 Ignarro L, Forstermann U, Lancaster JR. Third International Conference on the Biochemistry and Molecular Biology of Nitric Oxide Nitric Oxide. 2. DOI: 10.1006/Niox.1998.0174  0.469
1998 Furchgott RF, Ignarro LJ, Murrad F. The nobel assembly at the Karolinska Institute has decided to award the 1998 Nobel Prize in Physiology or Medicine jointly to Robert F. Furchgott, Louis J. Ignarro and Ferid Murad for their discoveries concerning nitric oxide as a signalling molecule in the cardiovascular system Review of Clinical Pharmacology and Pharmacokinetics, International Edition. 12: 105-107.  0.313
1997 Nene S, Gelabert H, Moore W, Quinones-Baldrich W, Santibanez-Gallerani A, Ignarro L. Cigarette Smoking Increases Endothelial-Derived Vasorelaxation in the Rat Carotid Artery in a Dose-Dependent Manner Journal of Surgical Research. 71: 101-106. PMID 9299276 DOI: 10.1006/Jsre.1997.5147  0.387
1997 Ding M, Wong JL, Rogers NE, Ignarro LJ, Voskuhl RR. Gender differences of inducible nitric oxide production in SJL/J mice with experimental autoimmune encephalomyelitis. Journal of Neuroimmunology. 77: 99-106. PMID 9209274 DOI: 10.1016/S0165-5728(97)00065-9  0.397
1997 Glasgow RE, Buga GM, Ignarro LJ, Chaudhuri G, Heymann MA. Endothelium-derived relaxing factor as a mediator of bradykinin-induced perinatal pulmonary vasodilatation in fetal sheep Reproduction, Fertility and Development. 9: 213-216. PMID 9208431 DOI: 10.1071/R96084  0.4
1997 Merrill JE, Murphy SP, Mitrovic B, Mackenzie-Graham A, Dopp JC, Ding M, Griscavage J, Ignarro LJ, Lowenstein CJ. Inducible nitric oxide synthase and nitric oxide production by oligodendrocytes Journal of Neuroscience Research. 48: 372-384. PMID 9169863 DOI: 10.1002/(Sici)1097-4547(19970515)48:4<372::Aid-Jnr9>3.0.Co;2-8  0.499
1997 Singh R, Pervin S, Rogers NE, Ignarro LJ, Chaudhuri G. Evidence for the presence of an unusual nitric oxide and citrulline-producing enzyme in rat kidney Biochemical and Biophysical Research Communications. 232: 672-677. PMID 9126334 DOI: 10.1006/Bbrc.1997.6354  0.505
1997 Ding M, St Pierre BA, Parkinson JF, Medberry P, Wong JL, Rogers NE, Ignarro LJ, Merrill JE. Inducible nitric-oxide synthase and nitric oxide production in human fetal astrocytes and microglia. A kinetic analysis. The Journal of Biological Chemistry. 272: 11327-35. PMID 9111039 DOI: 10.1074/Jbc.272.17.11327  0.483
1997 Ihnken K, Morita K, Buckberg GD, Winkelmann B, Schmitt M, Ignarro LJ, Sherman MP. Nitric-oxide-induced reoxygenation injury in the cyanotic immature heart is prevented by controlling oxygen content during initial reoxygenation Angiology. 48: 189-202. PMID 9071194 DOI: 10.1177/000331979704800301  0.444
1997 Mizuno A, Baretti R, Buckberg GD, Young HH, Vinten-Johansen J, Ma X.- L, Ignarro LJ, Yacoub MH, Sellke FW, Guyton RA. Endothelial stunning and myocyte recovery after reperfusion of jeopardized muscle: A role of L-arginine blood cardioplegia Journal of Thoracic and Cardiovascular Surgery. 113: 379-389. PMID 9040633 DOI: 10.1016/S0022-5223(97)70336-2  0.424
1997 Cicinelli E, Ignarro LJ, Lograno M, Matteo G, Falco N, Schonauer LM. Acute effects of transdermal estradiol administration on plasma levels of nitric oxide in postmenopausal women Fertility and Sterility. 67: 63-66. PMID 8986685 DOI: 10.1016/S0015-0282(97)81857-2  0.312
1997 Fukuto JM, Ignarro LJ. In VivoAspects of Nitric Oxide (NO) Chemistry:  Does Peroxynitrite (-OONO) Play a Major Role in Cytotoxicity? Accounts of Chemical Research. 30: 149-152. DOI: 10.1021/Ar960010Y  0.473
1996 Buga GM, Singh R, Pervin S, Rogers NE, Schmitz DA, Jenkinson CP, Cederbaum SD, Ignarro LJ. Arginase activity in endothelial cells: inhibition by NG-hydroxy-L-arginine during high-output NO production. The American Journal of Physiology. 271: H1988-98. PMID 8945918 DOI: 10.1152/Ajpheart.1996.271.5.H1988  0.47
1996 Cicinelli E, Ignarro LJ, Lograno M, Galantino P, Balzano G, Schonauer LM. Circulating levels of nitric oxide in fertile women in relation to the menstrual cycle Fertility and Sterility. 66: 1036-1038. PMID 8941078 DOI: 10.1016/S0015-0282(16)58706-8  0.442
1996 Morita K, Ihnken K, Buckberg GD, Ignarro LJ. Oxidative insult associated with hyperoxic cardiopulmonary bypass in the infantile heart and lung Japanese Circulation Journal. 60: 355-363. PMID 8844302 DOI: 10.1253/Jcj.60.355  0.459
1996 Sheng H, Ignarro LJ. Biochemical and immunohistochemical characterization of nitric oxide synthase in the rat retina Pharmacological Research. 33: 29-34. PMID 8817643 DOI: 10.1006/Phrs.1996.0005  0.468
1996 Hobbs AJ, Ignarro LJ. Nitric oxide-cyclic GMP signal transduction system Methods in Enzymology. 269: 134-148. PMID 8791644 DOI: 10.1016/S0076-6879(96)69016-8  0.47
1996 Cohen GA, Hobbs AJ, Fitch RM, Zinner MJ, Chaudhuri G, Ignarro LJ. Nitric oxide regulates endothelium-dependent vasodilator responses in rabbit hindquarters vascular bed in vivo. The American Journal of Physiology. 271: H133-9. PMID 8760168 DOI: 10.1152/Ajpheart.1996.271.1.H133  0.483
1996 Ignarro LJ. Physiology and pathophysiology of nitric oxide Kidney International, Supplement. S-2-S-5. PMID 8743501  0.452
1996 Lee J, Drinkwater D.C. J, Laks H, Chong A, Blitz A, Chen MA, Ignarro LJ, Chang P. Preservation of endothelium-dependent vasodilation with low-potassium University of Wisconsin solution Journal of Thoracic and Cardiovascular Surgery. 112: 103-110. PMID 8691853 DOI: 10.1016/S0022-5223(96)70183-6  0.424
1996 Morita K, Ihnken K, Buckberg GD, Sherman MP, Ignarro LJ. Pulmonary vasoconstriction due to impaired nitric oxide production after cardiopulmonary bypass Annals of Thoracic Surgery. 61: 1775-1780. PMID 8651783 DOI: 10.1016/0003-4975(96)00146-4  0.451
1996 Griscavage JM, Wilk S, Ignarro LJ. Inhibitors of the proteasome pathway interfere with induction of nitric oxide synthase in macrophages by blocking activation of transcription factor NF-κB Proceedings of the National Academy of Sciences of the United States of America. 93: 3308-3312. PMID 8622934 DOI: 10.1073/Pnas.93.8.3308  0.467
1996 Sherman MP, Wong VZ, Aeberhard EE, Fukuto JM, Ignarro LJ. Amplified nitric oxide production by pulmonary alveolar macrophages of newborn rats Redox Report. 2: 309-316.  0.346
1995 Hayashi T, Fukuto JM, Ignarro LJ, Chaudhuri G. Gender differences in atherosclerosis: Possible role of nitric oxide Journal of Cardiovascular Pharmacology. 26: 792-802. PMID 8637195 DOI: 10.1097/00005344-199511000-00017  0.377
1995 Radziszewski W, Chopra M, Zembowicz A, Gryglewski R, Ignarro LJ, Chaudhuri G. Nitric oxide donors induce extrusion of cyclic GMP from isolated human blood platelets by a mechanism which may be modulated by prostaglandins International Journal of Cardiology. 51: 211-220. PMID 8586470 DOI: 10.1016/0167-5273(95)02427-X  0.444
1995 Griscavage JM, Hobbs AJ, Ignarro LJ. Negative modulation of nitric oxide synthase by nitric oxide and nitroso compounds Advances in Pharmacology (San Diego, Calif.). 34: 215-234. PMID 8562436 DOI: 10.1016/S1054-3589(08)61088-1  0.523
1995 Mitrovic B, Ignarro LJ, Vinters HV, Akers MA, Schmid I, Uittenbogaart C, Merrill JE. Nitric oxide induces necrotic but not apoptotic cell death in oligodendrocytes Neuroscience. 65: 531-539. PMID 7777166 DOI: 10.1016/0306-4522(94)00491-M  0.472
1995 Abu-Soud HM, Wang J, Rousseau DL, Fukuto JM, Ignarro LJ, Stuehr DJ. Neuronal nitric oxide synthase self-inactivates by forming a ferrous-nitrosyl complex during aerobic catalysis Journal of Biological Chemistry. 270: 22997-23006. PMID 7559438 DOI: 10.1074/Jbc.270.39.22997  0.586
1995 Wang WW, Jenkinson CP, Griscavage JM, Kern RM, Arabolos NS, Byrns RE, Cederbaum SD, Ignarro LJ. Co-induction of Arginase and Nitric Oxide Synthase in Murine Macrophages Activated by Lipopolysaccharide Biochemical and Biophysical Research Communications. 210: 1009-1016. PMID 7539253 DOI: 10.1006/Bbrc.1995.1757  0.484
1995 Aeberhard EE, Henderson SA, Arabolos NS, Griscavage JM, Castro FE, Barrett CT, Ignarro LJ. Nonsteroidal anti-inflammatory drugs inhibit expression of the inducible nitric oxide synthase gene Biochemical and Biophysical Research Communications. 208: 1053-1059. PMID 7535524 DOI: 10.1006/Bbrc.1995.1441  0.479
1995 Patel AG, Toyama MT, Nguyen TN, Cohen GA, Ignarro LJ, Reber HA, Ashley SW. Role of nitric oxide in the relationship of pancreatic blood flow and exocrine secretion in cats. Gastroenterology. 108: 1215-20. PMID 7535273 DOI: 10.1016/0016-5085(95)90222-8  0.416
1995 Hyun J, Komori Y, Chaudhuri G, Ignarro LJ, Fukuto JM. The protective effect of tetrahydrobiopterin on the nitric oxide-mediated inhibition of purified nitric oxide synthase Biochemical and Biophysical Research Communications. 206: 380-386. PMID 7529500 DOI: 10.1006/Bbrc.1995.1052  0.522
1995 Ihnken K, Morita K, Buckberg GD, Ignarro LJ, Beyersdorf F. Reduction of reoxygenation injury and nitric oxide production in the cyanotic immature heart by controlling pO2 European Journal of Cardio-Thoracic Surgery. 9: 410-418. PMID 7495584 DOI: 10.1016/S1010-7940(05)80075-2  0.304
1995 Griscavage JM, Wilk S, Ignarro LJ. Serine and cysteine proteinase inhibitors prevent nitric oxide production by activated macrophages by interfering with transcription of the inducible NO synthase gene Biochemical and Biophysical Research Communications. 215: 721-729. PMID 7488014 DOI: 10.1006/bbrc.1995.2523  0.37
1995 Ihnken K, Morita K, Buckberg GD, Sherman MP, Ignarro LJ, Young HH. Studies of hypoxemic/reoxygenation injury: With aortic clamping. XIII. Interaction between oxygen tension and cardioplegiccomposition in limiting nitric oxide production and oxidant damage The Journal of Thoracic and Cardiovascular Surgery. 110: 1274-1286. PMID 7475179 DOI: 10.1016/S0022-5223(95)70014-5  0.457
1995 Morita K, Sherman MP, Buckberg GD, Ihnken K, Matheis G, Young HH, Ignarro LJ. Studies of hypoxemic/reoxygenation injury: Without aortic clamping:. V. Role of the l-arginine-nitric oxide pathway: The nitric oxide paradox The Journal of Thoracic and Cardiovascular Surgery. 110: 1200-1211. PMID 7475171 DOI: 10.1016/S0022-5223(95)70006-4  0.478
1995 Ding M, Pierre BS, Mitrovic B, Ignarro LJ, Merrill JE. Iglial cell production of no: possible role in multiple sclerosis Journal of Neuroimmunology. 63: 96. DOI: 10.1016/0165-5728(96)80964-7  0.356
1995 Shah S, Cuevas J, Hobbs A, Whang E, Ignarro L, Ashley S, Chaudhuri G. Enhanced actions of nitric oxide in modulating gastrointestinal smooth muscle function during pregnancy Gastroenterology. 108: A1246. DOI: 10.1016/0016-5085(95)29278-0  0.426
1995 Shah S, Cuevas J, Hobbs A, Whang E, Ashley S, Ignarro L, Chaudhuri G. Changes in gastrointestinal smooth muscle reactivity during pregnancy may be induced by nitric oxide Gastroenterology. 108: A688. DOI: 10.1016/0016-5085(95)27063-9  0.433
1995 Ihnken K, Morita K, Buckberg G, Beyersdorf F, Sherman M, Ignarro L, Goethe JW. Normoxic management of cyanotic immature hearts on CPB to reduce reoxygenation injury The Annals of Thoracic Surgery. 60: 864. DOI: 10.1016/0003-4975(95)92711-T  0.323
1994 Morita K, Ihnken K, Buckberg GD, Sherman MP, Young HH, Ignarro LJ. Role of controlled cardiac reoxygenation in reducing nitric oxide production and cardiac oxidant damage in cyanotic infantile hearts Journal of Clinical Investigation. 93: 2658-2666. PMID 8201004 DOI: 10.1172/Jci117279  0.394
1994 Mitrovic B, Ignarro LJ, Montestruque S, Smoll A, Merrill JE. Nitric oxide as a potential pathological mechanism in demyelination: its differential effects on primary glial cells in vitro. Neuroscience. 61: 575-85. PMID 7969931 DOI: 10.1016/0306-4522(94)90435-9  0.485
1994 Chang GJ, Woo P, Honda HM, Ignarro LJ, Young L, Berliner JA, Demer LL. Oxidation of LDL to a biologically active form by derivatives of nitric oxide and nitrite in the absence of superoxide: Dependence on pH and oxygen Arteriosclerosis, Thrombosis, and Vascular Biology. 14: 1808-1814. PMID 7947607 DOI: 10.1161/01.Atv.14.11.1808  0.497
1994 Ignarro LJ. Regulation of Cytosolic Guanylyl Cyclase by Porphyrins and Metalloporphyrins Advances in Pharmacology. 26: 35-65. PMID 7913618 DOI: 10.1016/S1054-3589(08)60050-2  0.445
1994 Mitrovic B, Martin FC, Charles AC, Ignarro LJ, Anton PA, Shanahan F, Merrill JE. Neurotransmitters and cytokines in CNS pathology. Progress in Brain Research. 103: 319-30. PMID 7533912 DOI: 10.1016/S0079-6123(08)61146-2  0.361
1994 Hobbs AJ, Fukuto JM, Ignarro LJ. Formation of free nitric oxide from L-arginine by nitric oxide synthase: Direct enhancement of generation by superoxide dismutase Proceedings of the National Academy of Sciences of the United States of America. 91: 10992-10996. PMID 7526387 DOI: 10.1073/Pnas.91.23.10992  0.506
1994 Henderson SA, Leet PH, Aeberhard EE, Adamst JW, Ignarro LJ, Murphy WJ, Sherman MP. Nitric oxide reduces early growth response-1 gene expression in rat lung macrophages treated with interferon-γ and lipopolysaccharide Journal of Biological Chemistry. 269: 25239-25242. PMID 7523382  0.373
1994 Slusher BS, Zacco AE, Maslanski JA, Norris TE, McLane MW, Moore WC, Rogers NE, Ignarro LJ. The cloned neurotensin receptor mediates cyclic GMP formation when coexpressed with nitric oxide synthase cDNA Molecular Pharmacology. 46: 115-121. PMID 7520123  0.399
1994 Sherman MP, Ignarro LJ. Nitric Oxide (No) Production By Pulmonary Alveolar Macrophages (Am) From Neonatal, Infant And Adult Rats Pediatric Research. 35: 269-269. DOI: 10.1203/00006450-199402000-00087  0.358
1994 Sherman MP, Buckberg GD, Monta K, Ihnken K, Ignarro LJ. Controlled Cardiac Reoxygenation Reduces Nitric Oxide (No) Production And Oxidant Injury Op Hypoxemic Infant Hearts Pediatric Research. 35: 260-260. DOI: 10.1203/00006450-199402000-00033  0.392
1994 Pearl JM, Laks H, Drinkwater DC, Sorensen TJ, Chang P, Aharon AS, Byrns RE, Ignarro LJ. Loss of endothelium-dependent vasodilatation and nitric oxide release after myocardial protection with University of Wisconsin solution. The Journal of Thoracic and Cardiovascular Surgery. 107: 257-264. DOI: 10.1016/S0022-5223(94)70479-1  0.465
1993 McNamara DB, Bedi B, Aurora H, Tena L, Ignarro LJ, Kadowitz PJ, Akers DL. L-arginine inhibits balloon catheter-induced intimal hyperplasia. Biochemical and Biophysical Research Communications. 193: 291-6. PMID 8503919 DOI: 10.1006/Bbrc.1993.1622  0.487
1993 McMahon TJ, Ignarro LJ, Kadowitz PJ. Influence of Zaprinast on vascular tone and vasodilator responses in the cat pulmonary vascular bed. Journal of Applied Physiology (Bethesda, Md. : 1985). 74: 1704-11. PMID 8390441 DOI: 10.1152/jappl.1993.74.4.1704  0.333
1993 Chaudhuri G, Cuevas J, Buga GM, Ignarro LJ. NO is more important than PGI2 in maintaining low vascular tone in feto- placental vessels American Journal of Physiology - Heart and Circulatory Physiology. 265. PMID 8285242 DOI: 10.1152/Ajpheart.1993.265.6.H2036  0.437
1993 Fukuto JM, Hobbs AJ, Ignarro LJ. Conversion of Nitroxyl (HNO) to Nitric Oxide (NO) in Biological Systems: The Role of Physiological Oxidants and Relevance to the Biological Activity of HNO Biochemical and Biophysical Research Communications. 196: 707-713. PMID 8240347 DOI: 10.1006/Bbrc.1993.2307  0.497
1993 Moriel EZ, Gonzalez-Cadavid N, Ignarro LJ, Byrns R, Rajfer J. Levels of nitric oxide metabolites do not increase during penile erection Urology. 42: 551-553. PMID 8236600 DOI: 10.1016/0090-4295(93)90271-B  0.449
1993 Gilliam MB, Sherman MP, Griscavage JM, Ignarro LJ. A spectrophotometric assay for nitrate using NADPH oxidation by Aspergillus nitrate reductase Analytical Biochemistry. 212: 359-365. PMID 8214577 DOI: 10.1006/Abio.1993.1341  0.445
1993 Buga GM, Griscavage JM, Rogers NE, Ignarro LJ. Negative feedback regulation of endothelial cell function by nitric oxide Circulation Research. 73: 808-812. PMID 7691429 DOI: 10.1161/01.Res.73.5.808  0.498
1993 Ignarro LJ, Fukuto JM, Griscavage JM, Rogers NE, Byrns RE. Oxidation of nitric oxide in aqueous solution to nitrite but not nitrate: Comparison with enzymatically formed nitric oxide from L-arginine Proceedings of the National Academy of Sciences of the United States of America. 90: 8103-8107. PMID 7690141 DOI: 10.1073/Pnas.90.17.8103  0.494
1993 Sherman MP, Aeberhard EE, Wong VZ, Griscavage JM, Ignarro LJ. Pyrrolidine dithiocarbamate inhibits induction of nitric oxide synthase activity in rat alveolar macrophages Biochemical and Biophysical Research Communications. 191: 1301-1308. PMID 7682068 DOI: 10.1006/Bbrc.1993.1359  0.472
1993 Ignarro LJ. Nitric oxide-mediated vasorelaxation. Thrombosis and Haemostasis. 70: 148-151. DOI: 10.1055/S-0038-1646177  0.491
1992 Matheis G, Sherman MP, Buckberg GD, Haybron DM, Young HH, Ignarro LJ. Role of L-arginine-nitric oxide pathway in myocardial reoxygenation injury. The American Journal of Physiology. 262: H616-20. PMID 1539723 DOI: 10.1152/Ajpheart.1992.262.2.H616  0.447
1992 Varela AF, Runge A, Ignarro LJ, Chaudhuri G. Nitric oxide and prostacyclin inhibit fetal platelet aggregation: A response similar to that observed in adults American Journal of Obstetrics and Gynecology. 167: 1599-1604. PMID 1471673 DOI: 10.1016/0002-9378(92)91748-Y  0.378
1992 Sherman MP, Griscavage JM, Ignarro LJ. Nitric oxide-mediated neuronal injury in multiple sclerosis Medical Hypotheses. 39: 143-146. PMID 1461176 DOI: 10.1016/0306-9877(92)90175-C  0.491
1992 Hayashi T, Fukuto JM, Ignarro LJ, Chaudhuri G. Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits: Implications for atherosclerosis Proceedings of the National Academy of Sciences of the United States of America. 89: 11259-11263. PMID 1454805 DOI: 10.1073/Pnas.89.23.11259  0.439
1992 Bush PA, Gonzalez NE, Ignarro LJ. Biosynthesis of nitric oxide and citrulline from l-arginine by constitutive nitric oxide synthase present in rabbit corpus cavernosum Biochemical and Biophysical Research Communications. 186: 308-314. PMID 1378725 DOI: 10.1016/S0006-291X(05)80808-3  0.488
1992 Bush PA, Gonzalez NE, Griscavage JM, Ignarro LJ. Nitric oxide synthase from cerebellum catalyzes the formation of equimolar quantities of nitric oxide and citrulline from L-arginine Biochemical and Biophysical Research Communications. 185: 960-966. PMID 1378272 DOI: 10.1016/0006-291X(92)91720-B  0.45
1992 Ignarro LJ. Haem-dependent activation of cytosolic guanylate cyclase by nitric oxide: a widespread signal transduction mechanism. Biochemical Society Transactions. 20: 465-469. PMID 1356858 DOI: 10.1042/Bst0200465  0.478
1992 Bush PA, Aronson WJ, Buga GM, Rajfer J, Ignarro LJ. Nitric oxide is a potent relaxant of human and rabbit corpus cavernosum. The Journal of Urology. 147: 1650-1655. PMID 1317469 DOI: 10.1016/S0022-5347(17)37671-1  0.45
1992 Buga GM, Ignarro LJ. Electrical field stimulation causes endothelium-dependent and nitric oxide-mediated relaxation of pulmonary artery American Journal of Physiology-Heart and Circulatory Physiology. 262. PMID 1314513 DOI: 10.1152/Ajpheart.1992.262.4.H973  0.485
1992 Rajfer J, Aronson WJ, Bush PA, Dorey FJ, Ignarro LJ. Nitric Oxide as a Mediator of Relaxation of the Corpus Cavernosum in Response to Nonadrenergic, Noncholinergic Neurotransmission The New England Journal of Medicine. 326: 90-94. PMID 1309211 DOI: 10.1056/Nejm199201093260203  0.483
1992 Rogers NE, Ignarro LJ. Constitutive nitric oxide synthase from cerebellum is reversibly inhibited by nitric oxide formed from L-arginine Biochemical and Biophysical Research Communications. 189: 242-249. PMID 1280418 DOI: 10.1016/0006-291X(92)91550-A  0.486
1992 Rajfer J, Aronson WJ, Bush PA, Dorey FJ, Ignarro LJ. Nitric Oxide as a Mediator of Relaxation of the Corpus Cavernosum in Response to Nonadrenergic, Noncholinergic Neurotransmission Obstetrical & Gynecological Survey. 47: 350-351. DOI: 10.1097/00006254-199205000-00026  0.48
1992 Ignarro LJ, Sherman MP, Buckberg GD. Physiological and pathophysiological roles of endothelium-derived nitric oxide (NO) in the heart Journal of Molecular and Cellular Cardiology. 24: 43. DOI: 10.1016/0022-2828(92)90159-W  0.477
1991 Buga GM, Gold ME, Fukuto JM, Ignarro LJ. Shear stress-induced release of nitric oxide from endothelial cells grown on beads Hypertension. 17: 187-193. PMID 1991651 DOI: 10.1161/01.Hyp.17.2.187  0.472
1991 Ross G, Chaudhuri G, Ignarro LJ, Chyu KY. Acetylcholine vasodilation of resistance vessels in vivo may not entirely depend on newly synthesized nitric oxide European Journal of Pharmacology. 195: 291-293. PMID 1874277 DOI: 10.1016/0014-2999(91)90549-6  0.479
1991 Chaudhuri G, Buga GM, Gold ME, Wood KS, Ignarro LJ. Characterization and actions of human umbilical endothelium derived relaxing factor British Journal of Pharmacology. 102: 331-336. PMID 1849765 DOI: 10.1111/J.1476-5381.1991.Tb12174.X  0.392
1991 Ignarro LJ. Signal transduction mechanisms involving nitric oxide Biochemical Pharmacology. 41: 485-490. PMID 1847633 DOI: 10.1016/0006-2952(91)90618-F  0.374
1991 Ignarro LJ. Heme-dependent activation of guanylate cyclase by nitric oxide: a novel signal transduction mechanism. Journal of Vascular Research. 28: 67-73. PMID 1672101 DOI: 10.1159/000158845  0.474
1991 Ignarro LJ. Physiological significance of endogenous nitric oxide. Seminars in Perinatology. 15: 20-26. DOI: 10.5555/Uri:Pii:0146000591900707  0.488
1991 Ignarro LJ, Wood KS, Fukuto JM. Continuous basal formation of endothelium-derived relaxing factor and muscle-derived relaxing factor, both of which are nitric oxide Journal of Cardiovascular Pharmacology. 17. DOI: 10.1097/00005344-199100001-00040  0.482
1990 Vargas HM, Ignarro LJ, Chaudhuri G. Physiological release of nitric oxide is dependent on the level of vascular tone European Journal of Pharmacology. 190: 393-397. PMID 2272376 DOI: 10.1016/0014-2999(90)94204-B  0.482
1990 Ignarro LJ. Biosynthesis and Metabolism of Endothelium-Derived Nitric Oxide Annual Review of Pharmacology and Toxicology. 30: 535-560. PMID 2188578 DOI: 10.1146/Annurev.Pa.30.040190.002535  0.458
1990 Gold ME, Wood KS, Byrns RE, Buga GM, Ignarro LJ. L-arginine-dependent vascular smooth muscle relaxation and cGMP formation. American Journal of Physiology-Heart and Circulatory Physiology. 259. PMID 2175566 DOI: 10.1152/Ajpheart.1990.259.6.H1813  0.429
1990 Ignarro LJ, Bush PA, Buga GM, Wood KS, Fukuto JM, Rajfer J. Nitric oxide and cyclic GMP formation upon electrical field stimulation cause relaxation of corpus cavernosum smooth muscle Biochemical and Biophysical Research Communications. 170: 843-850. PMID 2166511 DOI: 10.1016/0006-291X(90)92168-Y  0.437
1990 Wood KS, Buga GM, Byrns RE, Ignarro LJ. Vascular smooth muscle-derived relaxing factor (MDRF) and its close similarity to nitric oxide Biochemical and Biophysical Research Communications. 170: 80-88. PMID 2164813 DOI: 10.1016/0006-291X(90)91243-L  0.467
1990 Gold ME, Wood KS, Byrns RE, Fukuto J, Ignarro LJ. NG-methyl-L-arginine causes endothelium-dependent contraction and inhibition of cyclic GMP formation in artery and vein Proceedings of the National Academy of Sciences of the United States of America. 87: 4430-4434. PMID 2162040 DOI: 10.1073/Pnas.87.12.4430  0.477
1990 Fukuto JM, Wood KS, Byrns RE, Ignarro LJ. NG-Amino-L-arginine: A new potent antagonist of L-arginine-mediated endothelium-dependent relaxation Biochemical and Biophysical Research Communications. 168: 458-465. PMID 2159292 DOI: 10.1016/0006-291X(90)92343-X  0.431
1990 Gold ME, Buga GM, Wood KS, Byrns RE, Chaudhuri G, Ignarro LJ. Antagonistic modulatory roles of magnesium and calcium on release of endothelium-derived relaxing factor and smooth muscle tone. Circulation Research. 66: 355-66. PMID 2153470 DOI: 10.1161/01.Res.66.2.355  0.409
1990 Ignarro LJ. Haem‐Dependent Activation of Guanylate Cyclase and Cyclic GMP Formation by Endogenous Nitric Oxide: A Unique Transduction Mechanism for Transcellular Signaling Pharmacology & Toxicology. 67: 1-7. PMID 1975691 DOI: 10.1111/J.1600-0773.1990.Tb00772.X  0.47
1990 Ignarro LJ, Bush PA, Buga GM, Rajfer J. Neurotransmitter identity doubt. Nature. 347: 131-132. PMID 1975643 DOI: 10.1038/347131B0  0.309
1990 Gold ME, Fukuto JM, Ignarro LJ. Structural analogs of L-arginine cause endothelium-dependent and endothelium-independent, nitric oxide-mediated cyclic GMP formation and vasodilation, and cause vasoconstriction associated with decreased cyclic GMP formation European Journal of Pharmacology. 183: 1610-1611. DOI: 10.1016/0014-2999(90)94779-W  0.493
1989 Ignarro LJ. Endothelium-derived nitric oxide: actions and properties. The Faseb Journal. 3: 31-36. PMID 2642868 DOI: 10.1096/Fasebj.3.1.2642868  0.5
1989 Ignarro LJ. Biological actions and properties of endothelium-derived nitric oxide formed and released from artery and vein. Circulation Research. 65: 1-21. PMID 2544316 DOI: 10.1161/01.Res.65.1.1  0.377
1989 Buga GM, Gold ME, Wood KS, Chaudhuri G, Ignarro LJ. Endothelium-derived nitric oxide relaxes nonvascular smooth muscle European Journal of Pharmacology. 161: 61-72. PMID 2542037 DOI: 10.1016/0014-2999(89)90180-5  0.44
1989 Gold ME, Bush PA, Ignarro LJ. Depletion of arterial L-arginine causes reversible tolerance to endothelium-dependent relaxation. Biochemical and Biophysical Research Communications. 164: 714-721. PMID 2510722 DOI: 10.1016/0006-291X(89)91518-0  0.431
1989 Ignarro LJ. Endothelium-derived nitric oxide: pharmacology and relationship to the actions of organic nitrate esters. Pharmaceutical Research. 6: 651-659. PMID 2510139 DOI: 10.1023/A:1015926119947  0.487
1989 Gold ME, Wood KS, Buga GM, Byrns RE, Ignarro LJ. L-arginine causes whereas L-argininosuccinic acid inhibits endothelium-dependent vascular smooth muscle relaxation. Biochemical and Biophysical Research Communications. 161: 536-543. PMID 2500120 DOI: 10.1016/0006-291X(89)92632-6  0.466
1989 Ignarro LJ, Gold ME, Buga GM, Byrns RE, Wood KS, Chaudhuri G, Frank G. Basic polyamino acids rich in arginine, lysine, or ornithine cause both enhancement of and refractoriness to formation of endothelium-derived nitric oxide in pulmonary artery and vein. Circulation Research. 64: 315-29. PMID 2492213 DOI: 10.1161/01.Res.64.2.315  0.459
1988 Ignarro LJ, Buga GM, Chaudhuri G. EDRF generation and release from perfused bovine pulmonary artery and vein European Journal of Pharmacology. 149: 79-88. PMID 3135198 DOI: 10.1016/0014-2999(88)90045-3  0.396
1987 Ignarro LJ. Contributions to a quest. Nature. 330: 526-526. PMID 3500415 DOI: 10.1038/330526C0  0.32
1987 Ignarro LJ, Byrns RE, Wood KS. Endothelium-dependent modulation of cGMP levels and intrinsic smooth muscle tone in isolated bovine intrapulmonary artery and vein. Circulation Research. 60: 82-92. PMID 3032474 DOI: 10.1161/01.Res.60.1.82  0.418
1987 Ignarro LJ, Byrns RE, Buga GM, Wood KS. Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical. Circulation Research. 61: 866-879. PMID 2890446 DOI: 10.1161/01.Res.61.6.866  0.468
1987 Ignarro LJ, Wood KS. Activation of purified soluble guanylate cyclase by arachidonic acid requires absence of enzyme-bound heme. Biochimica Et Biophysica Acta. 928: 160-170. PMID 2882783 DOI: 10.1016/0167-4889(87)90117-0  0.408
1987 Ignarro LJ, Buga GM, Wood KS, Byrns RE, Chaudhuri G. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide Proceedings of the National Academy of Sciences of the United States of America. 84: 9265-9269. PMID 2827174 DOI: 10.1073/Pnas.84.24.9265  0.469
1987 Ignarro LJ, Byrns RE, Buga GM, Wood KS. Mechanisms of endothelium-dependent vascular smooth muscle relaxation elicited by bradykinin and VIP. American Journal of Physiology-Heart and Circulatory Physiology. 253. PMID 2825543 DOI: 10.1152/Ajpheart.1987.253.5.H1074  0.404
1985 Pretus HA, Ignarro LJ, Ensley HE, Feigen LP. Inhibition of soybean lipoxygenase by SKF 525-A and metyrapone. Prostaglandins. 30: 591-8. PMID 3936118 DOI: 10.1016/0090-6980(85)90023-1  0.403
1985 Lippton HL, Horwitz PM, McNamara DB, Ignarro LJ, Landry AZ, Hyman AL, Kadowitz PJ. The effects of amrinone on human platelet aggregation: evidence that amrinone does not act through a cyclic nucleotide mechanism in platelet rich plasma. Prostaglandins, Leukotrienes, and Medicine. 18: 193-204. PMID 3925461 DOI: 10.1016/0262-1746(85)90019-8  0.371
1985 Ignarro LJ, Harbison RG, Wood KS, Wolin MS, McNamara DB, Hyman AL, Kadowitz PJ. Differences in responsiveness of intrapulmonary artery and vein to arachidonic acid: Mechanism of arterial relaxation involves cyclic guanosine 3':5'-monophosphate and cyclic adenosine 3':5'-monophosphate Journal of Pharmacology and Experimental Therapeutics. 233: 560-569. PMID 2989487  0.552
1984 Ignarro LJ, Burke TM, Wood KS, Wolin MS, Kadowitz PJ. Association between cyclic GMP accumulation and acetylcholine-elicited relaxation of bovine intrapulmonary artery Journal of Pharmacology and Experimental Therapeutics. 228: 682-690. PMID 6323677  0.57
1984 Ignarro LJ, Wood KS, Wolin MS. Regulation of purified soluble guanylate cyclase by porphyrins and metalloporphyrins: a unifying concept Advances in Cyclic Nucleotide and Protein Phosphorylation Research. 17: 267-274. PMID 6145323  0.506
1984 Ignarro LJ, Wood KS, Ballot B, Wolin MS. Guanylate cyclase from bovine lung. Evidence that enzyme activation by phenylhydrazine is mediated by iron-phenyl hemoprotein complexes Journal of Biological Chemistry. 259: 5923-5931. PMID 6143758  0.549
1984 Feigen LP, Pretus H, Ignarro LJ. Inhibition of lipoxygenase enzyme in vitro by the cytochrome P-450 inhibitors metyrapone and SKF-525-A Prostaglandins. 28: 656-657. DOI: 10.1016/0090-6980(84)90158-8  0.399
1982 Ohlstein EH, Wood KS, Ignarro LJ. Purification and properties of heme-deficient hepatic soluble guanylate cyclase: Effects of heme and other factors on enzyme activation by NO, NO-heme, and protoporphyrin IX Archives of Biochemistry and Biophysics. 218: 187-198. PMID 6128958 DOI: 10.1016/0003-9861(82)90335-6  0.406
1982 Wolin MS, Wood KS, Ignarro LJ. Guanylate cyclase from bovine lung. A kinetic analysis of the regulation of the purified soluble enzyme by protoporphyrin IX, heme, and nitrosyl-heme Journal of Biological Chemistry. 257: 13312-13320. PMID 6128335  0.506
1982 Ignarro LJ, Degnan JN, Baricos WH, Kadowitz PJ, Wolin MS. Activation of purified guanylate cyclase by nitric oxide requires heme comparison of heme-deficient, heme-reconstituted and heme-containing forms of soluble enzyme from bovine lung Bba - General Subjects. 718: 49-59. PMID 6128034 DOI: 10.1016/0304-4165(82)90008-3  0.592
1982 Ignarro LJ, Wood KS, Wolin MS. Activation of purified soluble guanylate cyclase by protoporphyrin IX Proceedings of the National Academy of Sciences of the United States of America. 79: 2870-2873. PMID 6123998 DOI: 10.1073/Pnas.79.9.2870  0.618
1982 Lippton HL, Gruetter CA, Ignarro LJ, Meyer RL, Kadowitz PJ. Vasodilator actions of several N-nitroso compounds. Canadian Journal of Physiology and Pharmacology. 60: 68-75. PMID 6121616 DOI: 10.1139/Y82-009  0.417
1981 Gruetter CA, Ignarro LJ, Hyman AL, Kadowitz PJ. Contractile effects of 5-hydroxytryptamine in isolated intrapulmonary arteries and veins. Canadian Journal of Physiology and Pharmacology. 59: 157-62. PMID 7225942 DOI: 10.1139/Y81-026  0.365
1981 Kadowitz PJ, Nandiwada P, Gruetter CA, Ignarro LJ, Hyman AL. Pulmonary vasodilator responses to nitroprusside and nitroglycerin in the dog. The Journal of Clinical Investigation. 67: 893-902. PMID 6782123 DOI: 10.1172/Jci110107  0.391
1981 Edwards JC, Barry BK, Gruetter DY, Ohlstein EH, Baricos WH, Ignarro LJ. Activation of hepatic guanylate cyclase by nitrosyl-heme complexes. Comparison of unpurified and partially purified enzyme. Biochemical Pharmacology. 30: 2531-8. PMID 6118153 DOI: 10.1016/0006-2952(81)90579-7  0.428
1981 Ignarro LJ, Kadowitz PJ, Baricos WH. Evidence that regulation of hepatic guanylate cyclase activity involves interactions between catalytic site -SH groups and both substrate and activator. Archives of Biochemistry and Biophysics. 208: 75-86. PMID 6114709 DOI: 10.1016/0003-9861(81)90125-9  0.472
1981 McNamara DB, Kadowitz PJ, Hyman AL, Ignarro LJ. Adenosine 3',5'-monophosphate formation by preparations of rat liver soluble guanylate cyclase activated with nitric oxide, nitrosyl ferroheme, S-nitrosothiols, and other nitroso compounds. Canadian Journal of Physiology and Pharmacology. 58: 1446-56. PMID 6113040 DOI: 10.1139/Y80-219  0.443
1981 Gruetter CA, Kadowitz PJ, Ignarro LJ. Methylene blue inhibits coronary arterial relaxation and guanylate cyclase activation by nitroglycerin, sodium nitrite, and amyl nitrite. Canadian Journal of Physiology and Pharmacology. 59: 150-6. PMID 6112057 DOI: 10.1139/Y81-025  0.489
1981 Ignarro LJ, Barry BK, Gruetter DY, Ohlstein EH, Gruetter CA, Kadowitz PJ, Baricos WH. Selective alterations in responsiveness of guanylate cyclase to activation by nitroso compounds during enzyme purification. Biochimica Et Biophysica Acta. 673: 394-407. PMID 6112020 DOI: 10.1016/0304-4165(81)90471-2  0.411
1981 Mellion B, Ignarro L, Ohlstein E, Pontecorvo E, Hyman A, Kadowitz P. Evidence for the inhibitory role of guanosine 3', 5'-monophosphate in ADP-induced human platelet aggregation in the presence of nitric oxide and related vasodilators Blood. 57: 946-955. DOI: 10.1182/Blood.V57.5.946.Bloodjournal575946  0.395
1980 Gruetter DY, Gruetter CA, Barry BK, Baricos WH, Hyman AL, Kadowitz PJ, Ignarro LJ. Activation of coronary arterial guanylate cyclase by nitric oxide, nitroprusside, and nitrosoguanidine--inhibition by calcium, lanthanum, and other cations, enhancement by thiols. Biochemical Pharmacology. 29: 2943-50. PMID 6109533 DOI: 10.1016/0006-2952(80)90042-8  0.462
1980 Ignarro LJ, Gruetter CS. Requirement of thiols for activation of coronary arterial guanylate cyclase by glyceryl trinitrate and sodium nitrite: possible involvement of S-nitrosothiols. Biochimica Et Biophysica Acta. 631: 221-231. PMID 6105889 DOI: 10.1016/0304-4165(80)90297-4  0.507
1980 Ignarro LJ, Edwards JC, Gruetter DY, Barry BK, Gruetter CA. Possible involvement of S-nitrosothiols in the activation of guanylate cyclase by nitroso compounds. Febs Letters. 110: 275-8. PMID 6102928 DOI: 10.1016/0014-5793(80)80091-3  0.448
1979 Gruetter DY, Ignarro LJ. Arachidonic acid activation of guinea pig lung guanylate cyclase by two independent mechanisms Prostaglandins. 18: 541-556. PMID 43557 DOI: 10.1016/0090-6980(79)90022-4  0.401
1979 Ohlstein EH, Barry BK, Gruetter DY, Ignarro LJ. Methemoglobin blockade of coronary arterial soluble guanylate cyclase activation by nitroso compounds and its reversal with dithiothreitol. Febs Letters. 102: 316-20. PMID 37124 DOI: 10.1016/0014-5793(79)80026-5  0.364
1978 Ignarro LJ, Gross RA. Stimulation of mammalian adenylate cyclase activity with guanosine 5'-tetraphosphate and other guanine nucleotides. Biochimica Et Biophysica Acta. 541: 170-80. PMID 667124 DOI: 10.1016/0304-4165(78)90390-2  0.395
1978 Cech SY, Ignarro LJ. Cytidine 3',5'-monophosphate (cyclic CMP) formation by homogenates of mouse liver. Biochemical and Biophysical Research Communications. 80: 119-125. PMID 23778 DOI: 10.1016/0006-291X(78)91112-9  0.368
1977 Ignarro LJ. Glucocorticosteroid inhibition of nonphagocytic discharge of lysosomal enzymes from human neutrophils Arthritis & Rheumatism. 20: 73-83. PMID 836339 DOI: 10.1002/Art.1780200114  0.403
1977 Cech SY, Ignarro LJ. Cytidine 3',5'-monophosphate (cyclic CMP) formation in mammalian tissues. Science. 198: 1063-1065. PMID 22127 DOI: 10.1126/Science.22127  0.353
1976 Ignarro LJ, Cech SY. Bidirectional regulation of lysosomal enzyme secretion and phagocytosis in human neutrophils by guanosine 3',5'-monophosphate and adenosine 3',5'-monophosphate. Experimental Biology and Medicine. 151: 448-452. PMID 176668 DOI: 10.3181/00379727-151-39232  0.412
1975 Smith RJ, Ignarro LJ. Bioregulation of lysosomal enzyme secretion from human neutrophils: roles of guanosine 3':5'-monophosphate and calcium in stimulus-secretion coupling. Proceedings of the National Academy of Sciences of the United States of America. 72: 108-112. PMID 164009 DOI: 10.1073/Pnas.72.1.108  0.371
1974 Smith RJ, Ignarro LJ, Fisher JW. Lysosomal enzyme release: a possible mechanism of action of cobalt as an erythropoietic stimulant. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 146: 781-5. PMID 4841199 DOI: 10.3181/00379727-146-38192  0.382
1974 Ignarro LJ. Regulation of lysosomal enzyme secretion: role in inflammation. Inflammation Research. 4: 241-258. PMID 4374885 DOI: 10.1007/Bf01965227  0.414
1974 Ignarro LJ, Paddock RJ, George WJ. Hormonal Control of Neutrophil Lysosomal Enzyme Release: Effect of Epinephrine on Adenosine 3',5'-Monophosphate Science. 183: 855-857. PMID 4359340 DOI: 10.1126/Science.183.4127.855  0.386
1974 Ignarro LJ, George WJ. Hormonal Control of Lysosomal Enzyme Release from Human Neutrophils: Elevation of Cyclic Nucleotide Levels by Autonomic Neurohormones Proceedings of the National Academy of Sciences of the United States of America. 71: 2027-2031. PMID 4151956 DOI: 10.1073/Pnas.71.5.2027  0.388
1974 Ignarro LJ. Nonphagocytic release of neutral protease and β-glucuronidase from human neutrophils regulation by autonomic neurohormones and cyclic neucleotides Arthritis & Rheumatism. 17: 25-36. PMID 4149329 DOI: 10.1002/Art.1780170106  0.379
1973 Ignarro LJ. Neutral protease release from human leukocytes regulated by neurohormones and cyclic nucleotides. Nature. 245: 151-154. PMID 4147587 DOI: 10.1038/Newbio245151A0  0.384
1968 Ignarro LJ, Shideman FE. Norepinephrine and epinephrine in the embryo and embryonic heart of the chick: uptake and subcellular distribution. The Journal of Pharmacology and Experimental Therapeutics. 159: 49-58. PMID 5689403  0.677
1968 Ignarro LJ, Shideman FE. The requriement of sympathetic innervation for the active transport of norepinephrine by the heart. The Journal of Pharmacology and Experimental Therapeutics. 159: 59-65. PMID 5643950  0.685
1968 Ignarro LJ, Shideman FE. Appearance and concentrations of catecholamines and their biosynthesis in the embryonic and developing chick. The Journal of Pharmacology and Experimental Therapeutics. 159: 38-48. PMID 5643949  0.683
1968 Ignarro LJ, Shideman FE. Catechol-O-methyl transferase and monoamine oxidase activities in the heart and liver of the embryonic and developing chick. The Journal of Pharmacology and Experimental Therapeutics. 159: 29-37. PMID 5643948  0.688
1968 Ignarro LJ, Titus E. The presence of antagonistically acting alpha and beta adrenergic receptors in the mouse spleen Journal of Pharmacology and Experimental Therapeutics. 160: 72-80. PMID 5639112  0.231
1967 Shideman FE, Ignarro LJ. New species may create new problems: norepinephrine in the heart of the avian embryo. Federation Proceedings. 26: 1137-8. PMID 6028776  0.673
Show low-probability matches.