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Robert A. Lamb - Publications

Affiliations: 
Molecular Biosciences Northwestern University, Evanston, IL 
Area:
virology
Website:
http://www.molbiosci.northwestern.edu/people/core-faculty/robert-lamb.html
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284 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Lehman CW, Kehn-Hall K, Aggarwal M, Bracci NR, Pan HC, Panny L, Lamb RA, Lin SC. Resveratrol Inhibits Venezuelan Equine Encephalitis Virus Infection by Interfering with the AKT/GSK Pathway. Plants (Basel, Switzerland). 10. PMID 33673026 DOI: 10.3390/plants10020346  0.333
2020 Abdella R, Aggarwal M, Okura T, Lamb RA, He Y. Structure of a paramyxovirus polymerase complex reveals a unique methyltransferase-CTD conformation. Proceedings of the National Academy of Sciences of the United States of America. PMID 32075920 DOI: 10.1073/Pnas.1919837117  0.334
2020 Lamb RA. The Structure, Function, and Pathobiology of the Influenza A and B Virus Ion Channels. Cold Spring Harbor Perspectives in Medicine. PMID 31988204 DOI: 10.1101/Cshperspect.A038505  0.503
2020 Aggarwal M, Leser GP, Lamb RA. Repurposing papaverine as an antiviral agent against influenza viruses and paramyxoviruses. Journal of Virology. PMID 31896588 DOI: 10.1128/Jvi.01888-19  0.518
2019 Rima B, Balkema-Buschmann A, Dundon WG, Duprex P, Easton A, Fouchier R, Kurath G, Lamb R, Lee B, Rota P, Wang L, Ictv Report Consortium. ICTV Virus Taxonomy Profile: . The Journal of General Virology. PMID 31609197 DOI: 10.1099/Jgv.0.001328  0.497
2017 Aggarwal M, Leser GP, Kors CA, Lamb RA. Structure of the paramyxovirus PIV5 nucleoprotein in complex with an amino-terminal peptide of the phosphoprotein. Journal of Virology. PMID 29237836 DOI: 10.1128/Jvi.01304-17  0.336
2017 Rima B, Collins P, Easton A, Fouchier R, Kurath G, Lamb RA, Lee B, Maisner A, Rota P, Wang L, Ictv Report Consortium. ICTV Virus Taxonomy Profile: Pneumoviridae. The Journal of General Virology. PMID 29087278 DOI: 10.1099/Jgv.0.000959  0.43
2017 Wong JJW, Young TA, Zhang J, Liu S, Leser GP, Komives EA, Lamb RA, Zhou ZH, Salafsky J, Jardetzky TS. Monomeric ephrinB2 binding induces allosteric changes in Nipah virus G that precede its full activation. Nature Communications. 8: 781. PMID 28974687 DOI: 10.1038/S41467-017-00863-3  0.469
2017 Jardetzky T, Kuhn R, Lamb R. Editorial overview: Virus structure and functions. Current Opinion in Virology. 24: ix. PMID 28743434 DOI: 10.1016/J.Coviro.2017.07.006  0.44
2017 Leser GP, Lamb RA. The lateral organization of influenza virus proteins in the budozone region of the plasma membrane. Journal of Virology. PMID 28202765 DOI: 10.1128/Jvi.02104-16  0.478
2017 Wen X, Mousa JJ, Bates JT, Lamb RA, Crowe JE, Jardetzky TS. Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus. Nature Microbiology. 2: 16272. PMID 28134915 DOI: 10.1038/Nmicrobiol.2016.272  0.416
2016 Postler TS, Clawson AN, Amarasinghe GK, Basler CF, Bavari S, Benkő M, Blasdell KR, Briese T, Buchmeier MJ, Bukreyev A, Calisher CH, Chandran K, Charrel R, Clegg CS, Collins PL, ... ... Lamb RA, et al. Possibility and Challenges of Conversion of Current Virus Species Names to Linnaean Binomials. Systematic Biology. PMID 27798405 DOI: 10.1093/Sysbio/Syw096  0.374
2016 Adu-Gyamfi E, Kim LS, Jardetzky TS, Lamb RA. Flexibility of the head-stalk linker domain of paramyxovirus HN glycoprotein is essential for triggering virus fusion. Journal of Virology. PMID 27489276 DOI: 10.1128/Jvi.01187-16  0.6
2016 Song AS, Poor TA, Abriata LA, Jardetzky TS, Dal Peraro M, Lamb RA. Immobilization of the N-terminal helix stabilizes prefusion paramyxovirus fusion proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 27335462 DOI: 10.1073/Pnas.1608349113  0.494
2016 Adu-Gyamfi E, Kim LS, Jardetzky TS, Lamb RA. Mutagenesis of Paramyxovirus Hemagglutinin-Neuraminidase Membrane Proximal Stalk Region Influences Stability, Receptor Binding and Neuraminidase Activity. Journal of Virology. PMID 27334593 DOI: 10.1128/Jvi.00896-16  0.538
2016 Wen X, Pickens J, Mousa JJ, Leser GP, Lamb RA, Crowe JE, Jardetzky TS. A Chimeric Pneumovirus Fusion Protein Carrying Neutralizing Epitopes of Both MPV and RSV. Plos One. 11: e0155917. PMID 27224013 DOI: 10.1371/Journal.Pone.0155917  0.423
2015 Wong JJ, Paterson RG, Lamb RA, Jardetzky TS. Structure and stabilization of the Hendra virus F glycoprotein in its prefusion form. Proceedings of the National Academy of Sciences of the United States of America. PMID 26712026 DOI: 10.1073/Pnas.1523303113  0.509
2015 Li Z, Hung C, Paterson RG, Michel F, Fuentes S, Place R, Lin Y, Hogan RJ, Lamb RA, He B. Type II integral membrane protein, TM of J paramyxovirus promotes cell-to-cell fusion. Proceedings of the National Academy of Sciences of the United States of America. PMID 26392524 DOI: 10.1073/Pnas.1509476112  0.46
2015 Alayyoubi M, Leser GP, Kors CA, Lamb RA. Structure of the paramyxovirus parainfluenza virus 5 nucleoprotein-RNA complex. Proceedings of the National Academy of Sciences of the United States of America. 112: E1792-9. PMID 25831513 DOI: 10.1073/Pnas.1503941112  0.36
2015 Bose S, Jardetzky TS, Lamb RA. Timing is everything: Fine-tuned molecular machines orchestrate paramyxovirus entry. Virology. 479: 518-31. PMID 25771804 DOI: 10.1016/J.Virol.2015.02.037  0.683
2015 Poor TA, Song AS, Welch BD, Kors CA, Jardetzky TS, Lamb RA. On the stability of parainfluenza virus 5 F proteins. Journal of Virology. 89: 3438-41. PMID 25589638 DOI: 10.1128/Jvi.03221-14  0.481
2015 Roberts KL, Manicassamy B, Lamb RA. Influenza A virus uses intercellular connections to spread to neighboring cells. Journal of Virology. 89: 1537-49. PMID 25428869 DOI: 10.1128/Jvi.03306-14  0.539
2014 Wu Y, Canturk B, Jo H, Ma C, Gianti E, Klein ML, Pinto LH, Lamb RA, Fiorin G, Wang J, DeGrado WF. Flipping in the pore: discovery of dual inhibitors that bind in different orientations to the wild-type versus the amantadine-resistant S31N mutant of the influenza A virus M2 proton channel. Journal of the American Chemical Society. 136: 17987-95. PMID 25470189 DOI: 10.1021/Ja508461M  0.455
2014 Bruns AM, Leser GP, Lamb RA, Horvath CM. The innate immune sensor LGP2 activates antiviral signaling by regulating MDA5-RNA interaction and filament assembly. Molecular Cell. 55: 771-81. PMID 25127512 DOI: 10.1016/J.Molcel.2014.07.003  0.318
2014 Welch BD, Paduch M, Leser GP, Bergman Z, Kors CA, Paterson RG, Jardetzky TS, Kossiakoff AA, Lamb RA. Probing the functions of the paramyxovirus glycoproteins F and HN with a panel of synthetic antibodies. Journal of Virology. 88: 11713-25. PMID 25122782 DOI: 10.1128/Jvi.01707-14  0.539
2014 Rey-Carrizo M, Barniol-Xicota M, Ma C, Frigolé-Vivas M, Torres E, Naesens L, Llabrés S, Juárez-Jiménez J, Luque FJ, DeGrado WF, Lamb RA, Pinto LH, Vázquez S. Easily accessible polycyclic amines that inhibit the wild-type and amantadine-resistant mutants of the M2 channel of influenza A virus. Journal of Medicinal Chemistry. 57: 5738-47. PMID 24941437 DOI: 10.1021/Jm5005804  0.374
2014 Poor TA, Jones LM, Sood A, Leser GP, Plasencia MD, Rempel DL, Jardetzky TS, Woods RJ, Gross ML, Lamb RA. Probing the paramyxovirus fusion (F) protein-refolding event from pre- to postfusion by oxidative footprinting. Proceedings of the National Academy of Sciences of the United States of America. 111: E2596-605. PMID 24927585 DOI: 10.1073/Pnas.1408983111  0.437
2014 Jardetzky TS, Lamb RA. Activation of paramyxovirus membrane fusion and virus entry. Current Opinion in Virology. 5: 24-33. PMID 24530984 DOI: 10.1016/J.Coviro.2014.01.005  0.554
2014 Bose S, Song AS, Jardetzky TS, Lamb RA. Fusion activation through attachment protein stalk domains indicates a conserved core mechanism of paramyxovirus entry into cells. Journal of Virology. 88: 3925-41. PMID 24453369 DOI: 10.1128/Jvi.03741-13  0.696
2013 Rey-Carrizo M, Torres E, Ma C, Barniol-Xicota M, Wang J, Wu Y, Naesens L, DeGrado WF, Lamb RA, Pinto LH, Vázquez S. 3-Azatetracyclo[5.2.1.1(5,8).0(1,5)]undecane derivatives: from wild-type inhibitors of the M2 ion channel of influenza A virus to derivatives with potent activity against the V27A mutant. Journal of Medicinal Chemistry. 56: 9265-74. PMID 24237039 DOI: 10.1021/Jm401340P  0.367
2013 Ma C, Fiorin G, Carnevale V, Wang J, Lamb RA, Klein ML, Wu Y, Pinto LH, DeGrado WF. Asp44 stabilizes the Trp41 gate of the M2 proton channel of influenza A virus. Structure (London, England : 1993). 21: 2033-41. PMID 24139991 DOI: 10.1016/J.Str.2013.08.029  0.399
2013 Rossman JS, Lamb RA. Viral membrane scission. Annual Review of Cell and Developmental Biology. 29: 551-69. PMID 24099087 DOI: 10.1146/Annurev-Cellbio-101011-155838  0.468
2013 Bose S, Heath CM, Shah PA, Alayyoubi M, Jardetzky TS, Lamb RA. Mutations in the parainfluenza virus 5 fusion protein reveal domains important for fusion triggering and metastability. Journal of Virology. 87: 13520-31. PMID 24089572 DOI: 10.1128/Jvi.02123-13  0.679
2013 Welch BD, Yuan P, Bose S, Kors CA, Lamb RA, Jardetzky TS. Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) ectodomain. Plos Pathogens. 9: e1003534. PMID 23950713 DOI: 10.1371/Journal.Ppat.1003534  0.69
2013 Roberts KL, Leser GP, Ma C, Lamb RA. The amphipathic helix of influenza A virus M2 protein is required for filamentous bud formation and scission of filamentous and spherical particles. Journal of Virology. 87: 9973-82. PMID 23843641 DOI: 10.1128/Jvi.01363-13  0.522
2013 Lamb RA. Deadly H7N9 influenza virus: a pandemic in the making or a warning lesson? American Journal of Respiratory and Critical Care Medicine. 188: 1-2. PMID 23815712 DOI: 10.1164/Rccm.201305-0914Ed  0.554
2013 Wang J, Ma C, Wang J, Jo H, Canturk B, Fiorin G, Pinto LH, Lamb RA, Klein ML, DeGrado WF. Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virus. Journal of Medicinal Chemistry. 56: 2804-12. PMID 23437766 DOI: 10.1021/Jm301538E  0.417
2013 Balgi AD, Wang J, Cheng DY, Ma C, Pfeifer TA, Shimizu Y, Anderson HJ, Pinto LH, Lamb RA, DeGrado WF, Roberge M. Inhibitors of the influenza A virus M2 proton channel discovered using a high-throughput yeast growth restoration assay. Plos One. 8: e55271. PMID 23383318 DOI: 10.1371/Journal.Pone.0055271  0.335
2013 Wang J, Wu Y, Ma C, Fiorin G, Wang J, Pinto LH, Lamb RA, Klein ML, Degrado WF. Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus. Proceedings of the National Academy of Sciences of the United States of America. 110: 1315-20. PMID 23302696 DOI: 10.1073/Pnas.1216526110  0.37
2012 Welch BD, Liu Y, Kors CA, Leser GP, Jardetzky TS, Lamb RA. Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein. Proceedings of the National Academy of Sciences of the United States of America. 109: 16672-7. PMID 23012473 DOI: 10.1073/Pnas.1213802109  0.481
2012 Zokarkar A, Connolly SA, Jardetzky TS, Lamb RA. Reversible inhibition of fusion activity of a paramyxovirus fusion protein by an engineered disulfide bond in the membrane-proximal external region. Journal of Virology. 86: 12397-401. PMID 22951841 DOI: 10.1128/Jvi.02006-12  0.793
2012 Bose S, Zokarkar A, Welch BD, Leser GP, Jardetzky TS, Lamb RA. Fusion activation by a headless parainfluenza virus 5 hemagglutinin-neuraminidase stalk suggests a modular mechanism for triggering. Proceedings of the National Academy of Sciences of the United States of America. 109: E2625-34. PMID 22949640 DOI: 10.1073/Pnas.1213813109  0.821
2012 Yuan P, Paterson RG, Leser GP, Lamb RA, Jardetzky TS. Structure of the ulster strain newcastle disease virus hemagglutinin-neuraminidase reveals auto-inhibitory interactions associated with low virulence. Plos Pathogens. 8: e1002855. PMID 22912577 DOI: 10.1371/Journal.Ppat.1002855  0.513
2012 Rossman JS, Leser GP, Lamb RA. Filamentous influenza virus enters cells via macropinocytosis. Journal of Virology. 86: 10950-60. PMID 22875971 DOI: 10.1128/Jvi.05992-11  0.564
2012 Wen X, Krause JC, Leser GP, Cox RG, Lamb RA, Williams JV, Crowe JE, Jardetzky TS. Structure of the human metapneumovirus fusion protein with neutralizing antibody identifies a pneumovirus antigenic site. Nature Structural & Molecular Biology. 19: 461-3. PMID 22388735 DOI: 10.1038/Nsmb.2250  0.468
2012 Zokarkar A, Lamb RA. The paramyxovirus fusion protein C-terminal region: mutagenesis indicates an indivisible protein unit. Journal of Virology. 86: 2600-9. PMID 22171273 DOI: 10.1128/Jvi.06546-11  0.828
2012 Fiorin G, Carnevale V, Wang J, Ma C, Wang T, Hu F, Lamb R, Pinto L, Hong M, DeGrado W, Klein M. Mapping Water Density to Design New Blockers Against a Viral Proton Channel Biophysical Journal. 102: 682a. DOI: 10.1016/J.Bpj.2011.11.3708  0.442
2011 Kim YH, Donald JE, Grigoryan G, Leser GP, Fadeev AY, Lamb RA, DeGrado WF. Capture and imaging of a prehairpin fusion intermediate of the paramyxovirus PIV5. Proceedings of the National Academy of Sciences of the United States of America. 108: 20992-7. PMID 22178759 DOI: 10.1073/Pnas.1116034108  0.534
2011 Bose S, Welch BD, Kors CA, Yuan P, Jardetzky TS, Lamb RA. Structure and mutagenesis of the parainfluenza virus 5 hemagglutinin-neuraminidase stalk domain reveals a four-helix bundle and the role of the stalk in fusion promotion. Journal of Virology. 85: 12855-66. PMID 21994464 DOI: 10.1128/Jvi.06350-11  0.701
2011 Zhang L, Collins PL, Lamb RA, Pickles RJ. Comparison of differing cytopathic effects in human airway epithelium of parainfluenza virus 5 (W3A), parainfluenza virus type 3, and respiratory syncytial virus. Virology. 421: 67-77. PMID 21986028 DOI: 10.1016/J.Virol.2011.08.020  0.452
2011 Yuan P, Swanson KA, Leser GP, Paterson RG, Lamb RA, Jardetzky TS. Structure of the Newcastle disease virus hemagglutinin-neuraminidase (HN) ectodomain reveals a four-helix bundle stalk. Proceedings of the National Academy of Sciences of the United States of America. 108: 14920-5. PMID 21873198 DOI: 10.1073/Pnas.1111691108  0.534
2011 Wang J, Ma C, Wu Y, Lamb RA, Pinto LH, DeGrado WF. Exploring organosilane amines as potent inhibitors and structural probes of influenza a virus M2 proton channel. Journal of the American Chemical Society. 133: 13844-7. PMID 21819109 DOI: 10.1021/Ja2050666  0.427
2011 Wang J, Ma C, Fiorin G, Carnevale V, Wang T, Hu F, Lamb RA, Pinto LH, Hong M, Klein ML, DeGrado WF. Molecular dynamics simulation directed rational design of inhibitors targeting drug-resistant mutants of influenza A virus M2. Journal of the American Chemical Society. 133: 12834-41. PMID 21744829 DOI: 10.1021/Ja204969M  0.367
2011 Wang J, Ma C, Balannik V, Pinto LH, Lamb RA, Degrado WF. Exploring the Requirements for the Hydrophobic Scaffold and Polar Amine in inhibitors of M2 from Influenza A Virus. Acs Medicinal Chemistry Letters. 2: 307-312. PMID 21691418 DOI: 10.1021/Ml100297W  0.367
2011 Watanabe R, Leser GP, Lamb RA. Influenza virus is not restricted by tetherin whereas influenza VLP production is restricted by tetherin. Virology. 417: 50-6. PMID 21621240 DOI: 10.1016/J.Virol.2011.05.006  0.545
2011 Duque MD, Ma C, Torres E, Wang J, Naesens L, Juárez-Jiménez J, Camps P, Luque FJ, DeGrado WF, Lamb RA, Pinto LH, Vázquez S. Exploring the size limit of templates for inhibitors of the M2 ion channel of influenza A virus. Journal of Medicinal Chemistry. 54: 2646-57. PMID 21466220 DOI: 10.1021/Jm101334Y  0.428
2011 Rossman JS, Lamb RA. Influenza virus assembly and budding. Virology. 411: 229-36. PMID 21237476 DOI: 10.1016/J.Virol.2010.12.003  0.568
2011 Park M, Matsuura H, Lamb RA, Barron AE, Jardetzky TS. A fluorescence polarization assay using an engineered human respiratory syncytial virus F protein as a direct screening platform. Analytical Biochemistry. 409: 195-201. PMID 20971054 DOI: 10.1016/J.Ab.2010.10.020  0.476
2010 Polishchuk AL, Lear JD, Ma C, Lamb RA, Pinto LH, Degrado WF. A pH-dependent conformational ensemble mediates proton transport through the influenza A/M2 protein. Biochemistry. 49: 10061-71. PMID 20968306 DOI: 10.1021/Bi101229M  0.322
2010 Qi R, Hoose S, Schreiter J, Sawant KV, Lamb R, Ranjith-Kumar CT, Mills J, San Mateo L, Jordan JL, Kao CC. Secretion of the human Toll-like receptor 3 ectodomain is affected by single nucleotide polymorphisms and regulated by Unc93b1. The Journal of Biological Chemistry. 285: 36635-44. PMID 20855885 DOI: 10.1074/Jbc.M110.144402  0.342
2010 Rossman JS, Jing X, Leser GP, Lamb RA. Influenza virus M2 protein mediates ESCRT-independent membrane scission. Cell. 142: 902-13. PMID 20850012 DOI: 10.1016/J.Cell.2010.08.029  0.565
2010 Acharya R, Carnevale V, Fiorin G, Levine BG, Polishchuk AL, Balannik V, Samish I, Lamb RA, Pinto LH, DeGrado WF, Klein ML. Structure and mechanism of proton transport through the transmembrane tetrameric M2 protein bundle of the influenza A virus. Proceedings of the National Academy of Sciences of the United States of America. 107: 15075-80. PMID 20689043 DOI: 10.1073/Pnas.1007071107  0.398
2010 Robach JG, Lamb RA. Analysis of parainfluenza virus-5 hemagglutinin-neuraminidase protein mutants that are blocked in internalization and degradation. Virology. 406: 189-201. PMID 20684967 DOI: 10.1016/J.Virol.2010.06.049  0.826
2010 Ravid D, Leser GP, Lamb RA. A role for caveolin 1 in assembly and budding of the paramyxovirus parainfluenza virus 5. Journal of Virology. 84: 9749-59. PMID 20631121 DOI: 10.1128/Jvi.01079-10  0.574
2010 Watanabe R, Lamb RA. Influenza virus budding does not require a functional AAA+ ATPase, VPS4. Virus Research. 153: 58-63. PMID 20621136 DOI: 10.1016/J.Virusres.2010.07.006  0.526
2010 Swanson K, Wen X, Leser GP, Paterson RG, Lamb RA, Jardetzky TS. Structure of the Newcastle disease virus F protein in the post-fusion conformation. Virology. 402: 372-9. PMID 20439109 DOI: 10.1016/J.Virol.2010.03.050  0.501
2010 Rossman JS, Jing X, Leser GP, Balannik V, Pinto LH, Lamb RA. Influenza virus m2 ion channel protein is necessary for filamentous virion formation. Journal of Virology. 84: 5078-88. PMID 20219914 DOI: 10.1128/Jvi.00119-10  0.548
2010 Rossman JS, Lamb RA. Swine-origin influenza virus and the 2009 pandemic. American Journal of Respiratory and Critical Care Medicine. 181: 295-6. PMID 20130142 DOI: 10.1164/Rccm.200912-1876Ed  0.504
2010 Balannik V, Carnevale V, Fiorin G, Levine BG, Lamb RA, Klein ML, Degrado WF, Pinto LH. Functional studies and modeling of pore-lining residue mutants of the influenza a virus M2 ion channel. Biochemistry. 49: 696-708. PMID 20028125 DOI: 10.1021/Bi901799K  0.407
2010 Ma C, Ohigashi Y, Jing X, Lamb RA, Pinto LH. Pharmacological Relevant Amantadine Binding Site is in the Pore of Influenza a Virus M2 Proton Channel Biophysical Journal. 98: 539a. DOI: 10.1016/J.Bpj.2009.12.2926  0.476
2009 Balannik V, Wang J, Ohigashi Y, Jing X, Magavern E, Lamb RA, Degrado WF, Pinto LH. Design and pharmacological characterization of inhibitors of amantadine-resistant mutants of the M2 ion channel of influenza A virus. Biochemistry. 48: 11872-82. PMID 19905033 DOI: 10.1021/Bi9014488  0.38
2009 Ohigashi Y, Ma C, Jing X, Balannick V, Pinto LH, Lamb RA. An amantadine-sensitive chimeric BM2 ion channel of influenza B virus has implications for the mechanism of drug inhibition. Proceedings of the National Academy of Sciences of the United States of America. 106: 18775-9. PMID 19841275 DOI: 10.1073/Pnas.0910584106  0.422
2009 Rossman JS, Lamb RA. Autophagy, apoptosis, and the influenza virus M2 protein. Cell Host & Microbe. 6: 299-300. PMID 19837369 DOI: 10.1016/J.Chom.2009.09.009  0.517
2009 Connolly SA, Leser GP, Jardetzky TS, Lamb RA. Bimolecular complementation of paramyxovirus fusion and hemagglutinin-neuraminidase proteins enhances fusion: implications for the mechanism of fusion triggering. Journal of Virology. 83: 10857-68. PMID 19710150 DOI: 10.1128/Jvi.01191-09  0.491
2009 Ma C, Polishchuk AL, Ohigashi Y, Stouffer AL, Schön A, Magavern E, Jing X, Lear JD, Freire E, Lamb RA, DeGrado WF, Pinto LH. Identification of the functional core of the influenza A virus A/M2 proton-selective ion channel. Proceedings of the National Academy of Sciences of the United States of America. 106: 12283-8. PMID 19590009 DOI: 10.1073/Pnas.0905726106  0.482
2009 Bissonnette ML, Donald JE, DeGrado WF, Jardetzky TS, Lamb RA. Functional analysis of the transmembrane domain in paramyxovirus F protein-mediated membrane fusion. Journal of Molecular Biology. 386: 14-36. PMID 19121325 DOI: 10.1016/J.Jmb.2008.12.029  0.533
2009 Ma C, Polishchuk A, Ohigashi Y, DeGrado WF, Lamb RA, Pinto LH. Determining the Functional Core for Proton Transport, Ion Selectivity and Amantadine Sensitivity of the A/M2 Protein from Influenza A Virus Biophysical Journal. 96: 668a. DOI: 10.1016/J.Bpj.2008.12.3529  0.47
2009 Bujny MV, Bates M, Rossman J, Lamb RA, Zhuang X. High resolution optical microscopy analysis of Influenza Virus A assembly Biophysical Journal. 96: 420a-421a. DOI: 10.1016/J.Bpj.2008.12.2151  0.478
2008 Jackson D, Lamb RA. The influenza A virus spliced messenger RNA M mRNA3 is not required for viral replication in tissue culture. The Journal of General Virology. 89: 3097-101. PMID 19008398 DOI: 10.1099/Vir.0.2008/004739-0  0.446
2008 Chen BJ, Leser GP, Jackson D, Lamb RA. The influenza virus M2 protein cytoplasmic tail interacts with the M1 protein and influences virus assembly at the site of virus budding. Journal of Virology. 82: 10059-70. PMID 18701586 DOI: 10.1128/Jvi.01184-08  0.655
2008 Jing X, Ma C, Ohigashi Y, Oliveira FA, Jardetzky TS, Pinto LH, Lamb RA. Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel. Proceedings of the National Academy of Sciences of the United States of America. 105: 10967-72. PMID 18669647 DOI: 10.1073/Pnas.0804958105  0.374
2008 Stouffer AL, Ma C, Cristian L, Ohigashi Y, Lamb RA, Lear JD, Pinto LH, DeGrado WF. The interplay of functional tuning, drug resistance, and thermodynamic stability in the evolution of the M2 proton channel from the influenza A virus. Structure (London, England : 1993). 16: 1067-76. PMID 18611380 DOI: 10.1016/J.Str.2008.04.011  0.413
2008 Yuan P, Leser GP, Demeler B, Lamb RA, Jardetzky TS. Domain architecture and oligomerization properties of the paramyxovirus PIV 5 hemagglutinin-neuraminidase (HN) protein. Virology. 378: 282-91. PMID 18597807 DOI: 10.1016/J.Virol.2008.05.023  0.506
2008 Ma C, Soto CS, Ohigashi Y, Taylor A, Bournas V, Glawe B, Udo MK, Degrado WF, Lamb RA, Pinto LH. Identification of the pore-lining residues of the BM2 ion channel protein of influenza B virus. The Journal of Biological Chemistry. 283: 15921-31. PMID 18408016 DOI: 10.1074/Jbc.M710302200  0.515
2008 Jackson D, Hossain MJ, Hickman D, Perez DR, Lamb RA. A new influenza virus virulence determinant: the NS1 protein four C-terminal residues modulate pathogenicity. Proceedings of the National Academy of Sciences of the United States of America. 105: 4381-6. PMID 18334632 DOI: 10.1073/Pnas.0800482105  0.553
2008 Balannik V, Lamb RA, Pinto LH. The oligomeric state of the active BM2 ion channel protein of influenza B virus. The Journal of Biological Chemistry. 283: 4895-904. PMID 18073201 DOI: 10.1074/Jbc.M709433200  0.399
2008 Chen BJ, Lamb RA. Mechanisms for enveloped virus budding: can some viruses do without an ESCRT? Virology. 372: 221-32. PMID 18063004 DOI: 10.1016/J.Virol.2007.11.008  0.712
2007 Lamb RA, Jardetzky TS. Structural basis of viral invasion: lessons from paramyxovirus F. Current Opinion in Structural Biology. 17: 427-36. PMID 17870467 DOI: 10.1016/J.Sbi.2007.08.016  0.518
2007 Vega RA, Shen CK, Maspoch D, Robach JG, Lamb RA, Mirkin CA. Monitoring single-cell infectivity from virus-particle nanoarrays fabricated by parallel dip-pen nanolithography. Small (Weinheim An Der Bergstrasse, Germany). 3: 1482-5. PMID 17694589 DOI: 10.1002/Smll.200700244  0.782
2007 Backovic M, Leser GP, Lamb RA, Longnecker R, Jardetzky TS. Characterization of EBV gB indicates properties of both class I and class II viral fusion proteins. Virology. 368: 102-13. PMID 17655906 DOI: 10.1016/J.Virol.2007.06.031  0.485
2007 Chen BJ, Leser GP, Morita E, Lamb RA. Influenza virus hemagglutinin and neuraminidase, but not the matrix protein, are required for assembly and budding of plasmid-derived virus-like particles. Journal of Virology. 81: 7111-23. PMID 17475660 DOI: 10.1128/Jvi.00361-07  0.703
2007 Tompkins SM, Lin Y, Leser GP, Kramer KA, Haas DL, Howerth EW, Xu J, Kennett MJ, Durbin RK, Durbin JE, Tripp R, Lamb RA, He B. Recombinant parainfluenza virus 5 (PIV5) expressing the influenza A virus hemagglutinin provides immunity in mice to influenza A virus challenge. Virology. 362: 139-50. PMID 17254623 DOI: 10.1016/J.Virol.2006.12.005  0.505
2007 Pinto LH, Lamb RA. Controlling influenza virus replication by inhibiting its proton channel. Molecular Biosystems. 3: 18-23. PMID 17216051 DOI: 10.1039/B611613M  0.399
2007 Ranjith-Kumar CT, Miller W, Xiong J, Russell WK, Lamb R, Santos J, Duffy KE, Cleveland L, Park M, Bhardwaj K, Wu Z, Russell DH, Sarisky RT, Mbow ML, Kao CC. Biochemical and functional analyses of the human Toll-like receptor 3 ectodomain. The Journal of Biological Chemistry. 282: 7668-78. PMID 17209042 DOI: 10.1074/Jbc.M610946200  0.323
2006 Connolly SA, Leser GP, Yin HS, Jardetzky TS, Lamb RA. Refolding of a paramyxovirus F protein from prefusion to postfusion conformations observed by liposome binding and electron microscopy. Proceedings of the National Academy of Sciences of the United States of America. 103: 17903-8. PMID 17093041 DOI: 10.1073/Pnas.0608678103  0.408
2006 Hale BG, Jackson D, Chen YH, Lamb RA, Randall RE. Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling. Proceedings of the National Academy of Sciences of the United States of America. 103: 14194-9. PMID 16963558 DOI: 10.1073/Pnas.0606109103  0.553
2006 Connolly SA, Lamb RA. Paramyxovirus fusion: real-time measurement of parainfluenza virus 5 virus-cell fusion. Virology. 355: 203-12. PMID 16916528 DOI: 10.1016/J.Virol.2006.07.021  0.547
2006 Vega RA, Maspoch D, Shen CK, Kakkassery JJ, Chen BJ, Lamb RA, Mirkin CA. Functional antibody arrays through metal ion-affinity templates. Chembiochem : a European Journal of Chemical Biology. 7: 1653-7. PMID 16897679 DOI: 10.1002/Cbic.200600271  0.478
2006 Pinto LH, Lamb RA. Influenza virus proton channels. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. 5: 629-32. PMID 16761092 DOI: 10.1039/B517734K  0.492
2006 Bissonnette ML, Connolly SA, Young DF, Randall RE, Paterson RG, Lamb RA. Analysis of the pH requirement for membrane fusion of different isolates of the paramyxovirus parainfluenza virus 5. Journal of Virology. 80: 3071-7. PMID 16501116 DOI: 10.1128/Jvi.80.6.3071-3077.2006  0.432
2006 Pinto LH, Lamb RA. The M2 proton channels of influenza A and B viruses. The Journal of Biological Chemistry. 281: 8997-9000. PMID 16407184 DOI: 10.1074/Jbc.R500020200  0.535
2006 Yin HS, Wen X, Paterson RG, Lamb RA, Jardetzky TS. Structure of the parainfluenza virus 5 F protein in its metastable, prefusion conformation. Nature. 439: 38-44. PMID 16397490 DOI: 10.1038/Nature04322  0.531
2006 Lamb RA, Paterson RG, Jardetzky TS. Paramyxovirus membrane fusion: lessons from the F and HN atomic structures. Virology. 344: 30-7. PMID 16364733 DOI: 10.1016/J.Virol.2005.09.007  0.555
2005 Lamb RA, Jackson D. Extinct 1918 virus comes alive. Nature Medicine. 11: 1154-6. PMID 16270067 DOI: 10.1038/Nm1105-1154  0.467
2005 Leser GP, Lamb RA. Influenza virus assembly and budding in raft-derived microdomains: a quantitative analysis of the surface distribution of HA, NA and M2 proteins. Virology. 342: 215-27. PMID 16249012 DOI: 10.1016/J.Virol.2005.09.049  0.537
2005 Chen BJ, Takeda M, Lamb RA. Influenza virus hemagglutinin (H3 subtype) requires palmitoylation of its cytoplasmic tail for assembly: M1 proteins of two subtypes differ in their ability to support assembly. Journal of Virology. 79: 13673-84. PMID 16227287 DOI: 10.1128/Jvi.79.21.13673-13684.2005  0.715
2005 Schmitt AP, Lamb RA. Influenza virus assembly and budding at the viral budozone. Advances in Virus Research. 64: 383-416. PMID 16139601 DOI: 10.1016/S0065-3527(05)64012-2  0.563
2005 Yin HS, Paterson RG, Wen X, Lamb RA, Jardetzky TS. Structure of the uncleaved ectodomain of the paramyxovirus (hPIV3) fusion protein. Proceedings of the National Academy of Sciences of the United States of America. 102: 9288-93. PMID 15964978 DOI: 10.1073/Pnas.0503989102  0.549
2005 Yuan P, Thompson TB, Wurzburg BA, Paterson RG, Lamb RA, Jardetzky TS. Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose. Structure (London, England : 1993). 13: 803-15. PMID 15893670 DOI: 10.1016/J.Str.2005.02.019  0.546
2005 Venkataraman P, Lamb RA, Pinto LH. Chemical rescue of histidine selectivity filter mutants of the M2 ion channel of influenza A virus. The Journal of Biological Chemistry. 280: 21463-72. PMID 15784624 DOI: 10.1074/Jbc.M412406200  0.365
2005 Schmitt AP, Leser GP, Morita E, Sundquist WI, Lamb RA. Evidence for a new viral late-domain core sequence, FPIV, necessary for budding of a paramyxovirus. Journal of Virology. 79: 2988-97. PMID 15709019 DOI: 10.1128/Jvi.79.5.2988-2997.2005  0.534
2004 Russell CJ, Jardetzky TS, Lamb RA. Conserved glycine residues in the fusion peptide of the paramyxovirus fusion protein regulate activation of the native state. Journal of Virology. 78: 13727-42. PMID 15564482 DOI: 10.1128/Jvi.78.24.13727-13742.2004  0.498
2004 Schmitt AP, Lamb RA. Escaping from the cell: assembly and budding of negative-strand RNA viruses. Current Topics in Microbiology and Immunology. 283: 145-96. PMID 15298170 DOI: 10.1007/978-3-662-06099-5_5  0.482
2004 Waning DL, Russell CJ, Jardetzky TS, Lamb RA. Activation of a paramyxovirus fusion protein is modulated by inside-out signaling from the cytoplasmic tail. Proceedings of the National Academy of Sciences of the United States of America. 101: 9217-22. PMID 15197264 DOI: 10.1073/Pnas.0403339101  0.748
2004 Sun M, Rothermel TA, Shuman L, Aligo JA, Xu S, Lin Y, Lamb RA, He B. Conserved cysteine-rich domain of paramyxovirus simian virus 5 V protein plays an important role in blocking apoptosis. Journal of Virology. 78: 5068-78. PMID 15113888 DOI: 10.1128/Jvi.78.10.5068-5078.2004  0.412
2004 Jardetzky TS, Lamb RA. Virology: a class act. Nature. 427: 307-8. PMID 14737155 DOI: 10.1038/427307A  0.418
2003 Russell CJ, Kantor KL, Jardetzky TS, Lamb RA. A dual-functional paramyxovirus F protein regulatory switch segment: activation and membrane fusion. The Journal of Cell Biology. 163: 363-74. PMID 14581458 DOI: 10.1083/Jcb.200305130  0.432
2003 Tian C, Gao PF, Pinto LH, Lamb RA, Cross TA. Initial structural and dynamic characterization of the M2 protein transmembrane and amphipathic helices in lipid bilayers. Protein Science : a Publication of the Protein Society. 12: 2597-605. PMID 14573870 DOI: 10.1110/Ps.03168503  0.408
2003 Takeda M, Leser GP, Russell CJ, Lamb RA. Influenza virus hemagglutinin concentrates in lipid raft microdomains for efficient viral fusion. Proceedings of the National Academy of Sciences of the United States of America. 100: 14610-7. PMID 14561897 DOI: 10.1073/Pnas.2235620100  0.549
2003 Mould JA, Paterson RG, Takeda M, Ohigashi Y, Venkataraman P, Lamb RA, Pinto LH. Influenza B virus BM2 protein has ion channel activity that conducts protons across membranes. Developmental Cell. 5: 175-84. PMID 12852861 DOI: 10.1016/S1534-5807(03)00190-4  0.535
2003 Paterson RG, Takeda M, Ohigashi Y, Pinto LH, Lamb RA. Influenza B virus BM2 protein is an oligomeric integral membrane protein expressed at the cell surface. Virology. 306: 7-17. PMID 12620792 DOI: 10.1016/S0042-6822(02)00083-1  0.561
2003 Young DF, Andrejeva L, Livingstone A, Goodbourn S, Lamb RA, Collins PL, Elliott RM, Randall RE. Virus replication in engineered human cells that do not respond to interferons. Journal of Virology. 77: 2174-81. PMID 12525652 DOI: 10.1128/Jvi.77.3.2174-2181.2003  0.507
2002 Poole E, He B, Lamb RA, Randall RE, Goodbourn S. The V proteins of simian virus 5 and other paramyxoviruses inhibit induction of interferon-beta. Virology. 303: 33-46. PMID 12482656 DOI: 10.1006/Viro.2002.1737  0.37
2002 He B, Paterson RG, Stock N, Durbin JE, Durbin RK, Goodbourn S, Randall RE, Lamb RA. Recovery of paramyxovirus simian virus 5 with a V protein lacking the conserved cysteine-rich domain: the multifunctional V protein blocks both interferon-beta induction and interferon signaling. Virology. 303: 15-32. PMID 12482655 DOI: 10.1006/Viro.2002.1738  0.45
2002 Tian C, Tobler K, Lamb RA, Pinto LH, Cross TA. Expression and initial structural insights from solid-state NMR of the M2 proton channel from influenza A virus. Biochemistry. 41: 11294-300. PMID 12220196 DOI: 10.1021/Bi025695Q  0.421
2002 Waning DL, Schmitt AP, Leser GP, Lamb RA. Roles for the cytoplasmic tails of the fusion and hemagglutinin-neuraminidase proteins in budding of the paramyxovirus simian virus 5. Journal of Virology. 76: 9284-97. PMID 12186912 DOI: 10.1128/Jvi.76.18.9284-9297.2002  0.812
2002 Tang Y, Zaitseva F, Lamb RA, Pinto LH. The gate of the influenza virus M2 proton channel is formed by a single tryptophan residue. The Journal of Biological Chemistry. 277: 39880-6. PMID 12183461 DOI: 10.1074/Jbc.M206582200  0.421
2002 Schmitt AP, Leser GP, Waning DL, Lamb RA. Requirements for budding of paramyxovirus simian virus 5 virus-like particles. Journal of Virology. 76: 3952-64. PMID 11907235 DOI: 10.1128/Jvi.76.8.3952-3964.2002  0.813
2002 Takeda M, Pekosz A, Shuck K, Pinto LH, Lamb RA. Influenza a virus M2 ion channel activity is essential for efficient replication in tissue culture. Journal of Virology. 76: 1391-9. PMID 11773413 DOI: 10.1128/Jvi.76.3.1391-1399.2002  0.542
2001 Lamb RA, Takeda M. Death by influenza virus protein. Nature Medicine. 7: 1286-8. PMID 11726965 DOI: 10.1038/Nm1201-1286  0.557
2001 Russell CJ, Jardetzky TS, Lamb RA. Membrane fusion machines of paramyxoviruses: capture of intermediates of fusion. The Embo Journal. 20: 4024-34. PMID 11483506 DOI: 10.1093/Emboj/20.15.4024  0.456
2001 Parisien JP, Lau JF, Rodriguez JJ, Sullivan BM, Moscona A, Parks GD, Lamb RA, Horvath CM. The V protein of human parainfluenza virus 2 antagonizes type I interferon responses by destabilizing signal transducer and activator of transcription 2. Virology. 283: 230-9. PMID 11336548 DOI: 10.1006/Viro.2001.0856  0.42
2001 Dutch RE, Lamb RA. Deletion of the cytoplasmic tail of the fusion protein of the paramyxovirus simian virus 5 affects fusion pore enlargement. Journal of Virology. 75: 5363-9. PMID 11333918 DOI: 10.1128/Jvi.75.11.5363-5369.2001  0.509
2001 He B, Lin GY, Durbin JE, Durbin RK, Lamb RA. The SH integral membrane protein of the paramyxovirus simian virus 5 is required to block apoptosis in MDBK cells. Journal of Virology. 75: 4068-79. PMID 11287556 DOI: 10.1128/Jvi.75.9.4068-4079.2001  0.59
2001 Young DF, Chatziandreou N, He B, Goodbourn S, Lamb RA, Randall RE. Single amino acid substitution in the V protein of simian virus 5 differentiates its ability to block interferon signaling in human and murine cells. Journal of Virology. 75: 3363-70. PMID 11238862 DOI: 10.1128/Jvi.75.7.3363-3370.2001  0.508
2001 Dutch RE, Hagglund RN, Nagel MA, Paterson RG, Lamb RA. Paramyxovirus fusion (F) protein: a conformational change on cleavage activation. Virology. 281: 138-50. PMID 11222104 DOI: 10.1006/Viro.2000.0817  0.448
2001 Mould JA, Shuck K, Drury JE, Frings SM, Kaupp U, Pekosz A, Lamb RA, Pinto LH. Structure–function relationship of the M2 ion channel of influenza A virus International Congress Series. 1219: 389-396. DOI: 10.1016/S0531-5131(01)00641-0  0.323
2000 Dutch RE, Jardetzky TS, Lamb RA. Virus membrane fusion proteins: biological machines that undergo a metamorphosis. Bioscience Reports. 20: 597-612. PMID 11426696 DOI: 10.1023/A:1010467106305  0.552
2000 Pekosz A, Lamb RA. Identification of a membrane targeting and degradation signal in the p42 protein of influenza C virus. Journal of Virology. 74: 10480-8. PMID 11044092 DOI: 10.1128/Jvi.74.22.10480-10488.2000  0.49
2000 Lin GY, Lamb RA. The paramyxovirus simian virus 5 V protein slows progression of the cell cycle. Journal of Virology. 74: 9152-66. PMID 10982362 DOI: 10.1128/Jvi.74.19.9152-9166.2000  0.597
2000 Shuck K, Lamb RA, Pinto LH. Analysis of the pore structure of the influenza A virus M(2) ion channel by the substituted-cysteine accessibility method. Journal of Virology. 74: 7755-61. PMID 10933681 DOI: 10.1128/Jvi.74.17.7755-7761.2000  0.427
2000 Mould JA, Drury JE, Frings SM, Kaupp UB, Pekosz A, Lamb RA, Pinto LH. Permeation and activation of the M2 ion channel of influenza A virus. The Journal of Biological Chemistry. 275: 31038-50. PMID 10913133 DOI: 10.1074/Jbc.M003663200  0.457
2000 Zhang J, Pekosz A, Lamb RA. Influenza virus assembly and lipid raft microdomains: a role for the cytoplasmic tails of the spike glycoproteins. Journal of Virology. 74: 4634-44. PMID 10775599 DOI: 10.1128/Jvi.74.10.4634-4644.2000  0.56
2000 Paterson RG, Russell CJ, Lamb RA. Fusion protein of the paramyxovirus SV5: destabilizing and stabilizing mutants of fusion activation. Virology. 270: 17-30. PMID 10772976 DOI: 10.1006/Viro.2000.0267  0.51
2000 Zhang J, Leser GP, Pekosz A, Lamb RA. The cytoplasmic tails of the influenza virus spike glycoproteins are required for normal genome packaging. Virology. 269: 325-34. PMID 10753711 DOI: 10.1006/Viro.2000.0228  0.539
2000 Mould JA, Li HC, Dudlak CS, Lear JD, Pekosz A, Lamb RA, Pinto LH. Mechanism for proton conduction of the M(2) ion channel of influenza A virus. The Journal of Biological Chemistry. 275: 8592-9. PMID 10722698 DOI: 10.1074/Jbc.275.12.8592  0.36
1999 Tobler K, Kelly ML, Pinto LH, Lamb RA. Effect of cytoplasmic tail truncations on the activity of the M(2) ion channel of influenza A virus. Journal of Virology. 73: 9695-701. PMID 10559278 DOI: 10.1128/Jvi.73.12.9695-9701.1999  0.431
1999 Leser GP, Ector KJ, Ng DT, Shaughnessy MA, Lamb RA. The signal for clathrin-mediated endocytosis of the paramyxovirus SV5 HN protein resides at the transmembrane domain-ectodomain boundary region. Virology. 262: 79-92. PMID 10489343 DOI: 10.1006/Viro.1999.9890  0.779
1999 Pekosz A, Lamb RA. Cell surface expression of biologically active influenza C virus HEF glycoprotein expressed from cDNA. Journal of Virology. 73: 8808-12. PMID 10482635 DOI: 10.1128/Jvi.73.10.8808-8812.1999  0.501
1999 Schmitt AP, He B, Lamb RA. Involvement of the cytoplasmic domain of the hemagglutinin-neuraminidase protein in assembly of the paramyxovirus simian virus 5. Journal of Virology. 73: 8703-12. PMID 10482624 DOI: 10.1128/Jvi.73.10.8703-8712.1999  0.582
1999 Pekosz A, He B, Lamb RA. Reverse genetics of negative-strand RNA viruses: closing the circle. Proceedings of the National Academy of Sciences of the United States of America. 96: 8804-6. PMID 10430844 DOI: 10.1073/Pnas.96.16.8804  0.455
1999 He B, Lamb RA. Effect of inserting paramyxovirus simian virus 5 gene junctions at the HN/L gene junction: analysis of accumulation of mRNAs transcribed from rescued viable viruses. Journal of Virology. 73: 6228-34. PMID 10400712 DOI: 10.1128/Jvi.73.8.6228-6234.1999  0.404
1999 Lamb RA, Joshi SB, Dutch RE. The paramyxovirus fusion protein forms an extremely stable core trimer: structural parallels to influenza virus haemagglutinin and HIV-1 gp41. Molecular Membrane Biology. 16: 11-9. PMID 10332733 DOI: 10.1080/096876899294715  0.469
1999 Baker KA, Dutch RE, Lamb RA, Jardetzky TS. Structural basis for paramyxovirus-mediated membrane fusion. Molecular Cell. 3: 309-19. PMID 10198633 DOI: 10.1016/S1097-2765(00)80458-X  0.493
1999 Gandhi CS, Shuck K, Lear JD, Dieckmann GR, DeGrado WF, Lamb RA, Pinto LH. Cu(II) inhibition of the proton translocation machinery of the influenza A virus M2 protein. The Journal of Biological Chemistry. 274: 5474-82. PMID 10026160 DOI: 10.1074/Jbc.274.9.5474  0.374
1999 Bauer CM, Pinto LH, Cross TA, Lamb RA. The influenza virus M2 ion channel protein: probing the structure of the transmembrane domain in intact cells by using engineered disulfide cross-linking. Virology. 254: 196-209. PMID 9927586 DOI: 10.1006/Viro.1998.9552  0.435
1998 Pekosz A, Lamb RA. Influenza C virus CM2 integral membrane glycoprotein is produced from a polypeptide precursor by cleavage of an internal signal sequence. Proceedings of the National Academy of Sciences of the United States of America. 95: 13233-8. PMID 9789071 DOI: 10.1073/Pnas.95.22.13233  0.461
1998 He B, Leser GP, Paterson RG, Lamb RA. The paramyxovirus SV5 small hydrophobic (SH) protein is not essential for virus growth in tissue culture cells. Virology. 250: 30-40. PMID 9770417 DOI: 10.1006/Viro.1998.9354  0.566
1998 Lin GY, Paterson RG, Richardson CD, Lamb RA. The V protein of the paramyxovirus SV5 interacts with damage-specific DNA binding protein. Virology. 249: 189-200. PMID 9740790 DOI: 10.1006/Viro.1998.9317  0.621
1998 Dutch RE, Joshi SB, Lamb RA. Membrane fusion promoted by increasing surface densities of the paramyxovirus F and HN proteins: comparison of fusion reactions mediated by simian virus 5 F, human parainfluenza virus type 3 F, and influenza virus HA. Journal of Virology. 72: 7745-53. PMID 9733810 DOI: 10.1128/Jvi.72.10.7745-7753.1998  0.555
1998 Joshi SB, Dutch RE, Lamb RA. A core trimer of the paramyxovirus fusion protein: parallels to influenza virus hemagglutinin and HIV-1 gp41. Virology. 248: 20-34. PMID 9705252 DOI: 10.1006/Viro.1998.9242  0.458
1998 Roberts PC, Lamb RA, Compans RW. The M1 and M2 proteins of influenza A virus are important determinants in filamentous particle formation. Virology. 240: 127-37. PMID 9448697 DOI: 10.1006/Viro.1997.8916  0.429
1997 Zhou J, Dutch RE, Lamb RA. Proper spacing between heptad repeat B and the transmembrane domain boundary of the paramyxovirus SV5 F protein is critical for biological activity. Virology. 239: 327-39. PMID 9434724 DOI: 10.1006/Viro.1997.8917  0.468
1997 Lin GY, Paterson RG, Lamb RA. The RNA binding region of the paramyxovirus SV5 V and P proteins. Virology. 238: 460-9. PMID 9400618 DOI: 10.1006/Viro.1997.8866  0.545
1997 Bagai S, Lamb RA. A glycine to alanine substitution in the paramyxovirus SV5 fusion peptide increases the initial rate of fusion. Virology. 238: 283-90. PMID 9400601 DOI: 10.1006/Viro.1997.8858  0.48
1997 Pekosz A, Lamb RA. The CM2 protein of influenza C virus is an oligomeric integral membrane glycoprotein structurally analogous to influenza A virus M2 and influenza B virus NB proteins. Virology. 237: 439-51. PMID 9356355 DOI: 10.1006/Viro.1997.8788  0.564
1997 He B, Paterson RG, Ward CD, Lamb RA. Recovery of infectious SV5 from cloned DNA and expression of a foreign gene. Virology. 237: 249-60. PMID 9356337 DOI: 10.1006/Viro.1997.8801  0.407
1997 Huang XF, Compans RW, Chen S, Lamb RA, Arvan P. Polarized apical targeting directed by the signal/anchor region of simian virus 5 hemagglutinin-neuraminidase. The Journal of Biological Chemistry. 272: 27598-604. PMID 9346896 DOI: 10.1074/Jbc.272.44.27598  0.468
1997 Paterson RG, Johnson ML, Lamb RA. Paramyxovirus fusion (F) protein and hemagglutinin-neuraminidase (HN) protein interactions: intracellular retention of F and HN does not affect transport of the homotypic HN or F protein. Virology. 237: 1-9. PMID 9344902 DOI: 10.1006/Viro.1997.8759  0.531
1997 Pinto LH, Dieckmann GR, Gandhi CS, Papworth CG, Braman J, Shaughnessy MA, Lear JD, Lamb RA, DeGrado WF. A functionally defined model for the M2 proton channel of influenza A virus suggests a mechanism for its ion selectivity. Proceedings of the National Academy of Sciences of the United States of America. 94: 11301-6. PMID 9326604 DOI: 10.1073/Pnas.94.21.11301  0.495
1997 Brassard DL, Lamb RA. Expression of influenza B virus hemagglutinin containing multibasic residue cleavage sites. Virology. 236: 234-48. PMID 9325231 DOI: 10.1006/Viro.1997.8749  0.504
1997 Melikyan GB, Jin H, Lamb RA, Cohen FS. The role of the cytoplasmic tail region of influenza virus hemagglutinin in formation and growth of fusion pores. Virology. 235: 118-28. PMID 9300043 DOI: 10.1006/Viro.1997.8686  0.452
1997 Sakaguchi T, Tu Q, Pinto LH, Lamb RA. The active oligomeric state of the minimalistic influenza virus M2 ion channel is a tetramer. Proceedings of the National Academy of Sciences of the United States of America. 94: 5000-5. PMID 9144179 DOI: 10.1073/Pnas.94.10.5000  0.535
1997 Jin H, Leser GP, Zhang J, Lamb RA. Influenza virus hemagglutinin and neuraminidase cytoplasmic tails control particle shape. The Embo Journal. 16: 1236-47. PMID 9135140 DOI: 10.1093/Emboj/16.6.1236  0.528
1997 Lamb RA, Pinto LH. Do Vpu and Vpr of human immunodeficiency virus type 1 and NB of influenza B virus have ion channel activities in the viral life cycles? Virology. 229: 1-11. PMID 9123850 DOI: 10.1006/Viro.1997.8451  0.473
1996 Zhang J, Lamb RA. Characterization of the membrane association of the influenza virus matrix protein in living cells. Virology. 225: 255-66. PMID 8918911 DOI: 10.1006/Viro.1996.0599  0.506
1996 Bagai S, Lamb RA. Truncation of the COOH-terminal region of the paramyxovirus SV5 fusion protein leads to hemifusion but not complete fusion. The Journal of Cell Biology. 135: 73-84. PMID 8858164 DOI: 10.1083/Jcb.135.1.73  0.515
1996 Shimbo K, Brassard DL, Lamb RA, Pinto LH. Ion selectivity and activation of the M2 ion channel of influenza virus. Biophysical Journal. 70: 1335-46. PMID 8785289 DOI: 10.1016/S0006-3495(96)79690-X  0.393
1996 Leser GP, Ector KJ, Lamb RA. The paramyxovirus simian virus 5 hemagglutinin-neuraminidase glycoprotein, but not the fusion glycoprotein, is internalized via coated pits and enters the endocytic pathway. Molecular Biology of the Cell. 7: 155-72. PMID 8741847 DOI: 10.1091/Mbc.7.1.155  0.55
1996 Tu Q, Pinto LH, Luo G, Shaughnessy MA, Mullaney D, Kurtz S, Krystal M, Lamb RA. Characterization of inhibition of M2 ion channel activity by BL-1743, an inhibitor of influenza A virus. Journal of Virology. 70: 4246-52. PMID 8676445 DOI: 10.1128/Jvi.70.7.4246-4252.1996  0.452
1996 Sakaguchi T, Leser GP, Lamb RA. The ion channel activity of the influenza virus M2 protein affects transport through the Golgi apparatus. The Journal of Cell Biology. 133: 733-47. PMID 8666660 DOI: 10.1083/Jcb.133.4.733  0.444
1996 Brassard DL, Leser GP, Lamb RA. Influenza B virus NB glycoprotein is a component of the virion. Virology. 220: 350-60. PMID 8661386 DOI: 10.1006/Viro.1996.0323  0.537
1996 Jin H, Subbarao K, Bagai S, Leser GP, Murphy BR, Lamb RA. Palmitylation of the influenza virus hemagglutinin (H3) is not essential for virus assembly or infectivity. Journal of Virology. 70: 1406-14. PMID 8627657 DOI: 10.1128/Jvi.70.3.1406-1414.1996  0.54
1995 Paterson RG, Leser GP, Shaughnessy MA, Lamb RA. The paramyxovirus SV5 V protein binds two atoms of zinc and is a structural component of virions. Virology. 208: 121-31. PMID 11831692 DOI: 10.1006/Viro.1995.1135  0.459
1995 Shimbo K, Brassard DL, Lamb RA, Pinto LH. Viral and cellular small integral membrane proteins can modify ion channels endogenous to Xenopus oocytes. Biophysical Journal. 69: 1819-29. PMID 8580325 DOI: 10.1016/S0006-3495(95)80052-4  0.437
1995 Wang C, Lamb RA, Pinto LH. Activation of the M2 ion channel of influenza virus: a role for the transmembrane domain histidine residue. Biophysical Journal. 69: 1363-71. PMID 8534806 DOI: 10.1016/S0006-3495(95)80003-2  0.386
1995 Schneemann A, Schneider PA, Lamb RA, Lipkin WI. The remarkable coding strategy of borna disease virus: a new member of the nonsegmented negative strand RNA viruses. Virology. 210: 1-8. PMID 7793061 DOI: 10.1006/Viro.1995.1311  0.347
1995 Bagai S, Lamb RA. Individual roles of N-linked oligosaccharide chains in intracellular transport of the paramyxovirus SV5 fusion protein. Virology. 209: 250-6. PMID 7747477 DOI: 10.1006/Viro.1995.1251  0.453
1995 Ward CD, Paterson RG, Lamb RA. Mutants of the paramyxovirus SV5 fusion protein: regulated and extensive syncytium formation. Virology. 209: 242-9. PMID 7747476 DOI: 10.1006/Viro.1995.1250  0.516
1995 Hughey PG, Roberts PC, Holsinger LJ, Zebedee SL, Lamb RA, Compans RW. Effects of antibody to the influenza A virus M2 protein on M2 surface expression and virus assembly. Virology. 212: 411-21. PMID 7571410 DOI: 10.1006/Viro.1995.1498  0.498
1995 Pinto LH, Lamb RA. Understanding the mechanism of action of the anti-influenza virus drug amantadine. Trends in Microbiology. 3: 271. PMID 7551640 DOI: 10.1016/S0966-842X(00)88942-8  0.388
1995 Holsinger LJ, Shaughnessy MA, Micko A, Pinto LH, Lamb RA. Analysis of the posttranslational modifications of the influenza virus M2 protein. Journal of Virology. 69: 1219-25. PMID 7529332 DOI: 10.1128/Jvi.69.2.1219-1225.1995  0.477
1995 Bagai S, Lamb RA. Quantitative measurement of paramyxovirus fusion: differences in requirements of glycoproteins between simian virus 5 and human parainfluenza virus 3 or Newcastle disease virus. Journal of Virology. 69: 6712-9. PMID 7474081 DOI: 10.1128/Jvi.69.11.6712-6719.1995  0.597
1994 Russell R, Paterson RG, Lamb RA. Studies with cross-linking reagents on the oligomeric form of the paramyxovirus fusion protein. Virology. 199: 160-8. PMID 8116239 DOI: 10.1006/Viro.1994.1108  0.491
1994 Jin H, Leser GP, Lamb RA. The influenza virus hemagglutinin cytoplasmic tail is not essential for virus assembly or infectivity. The Embo Journal. 13: 5504-15. PMID 7957116 DOI: 10.1002/J.1460-2075.1994.Tb06885.X  0.566
1994 Tosteson MT, Pinto LH, Holsinger LJ, Lamb RA. Reconstitution of the influenza virus M2 ion channel in lipid bilayers. The Journal of Membrane Biology. 142: 117-26. PMID 7535851 DOI: 10.1007/Bf00233389  0.45
1994 Wang C, Lamb RA, Pinto LH. Direct measurement of the influenza A virus M2 protein ion channel activity in mammalian cells. Virology. 205: 133-40. PMID 7526533 DOI: 10.1006/Viro.1994.1628  0.523
1994 Takeuchi K, Shaughnessy MA, Lamb RA. Influenza virus M2 protein ion channel activity is not required to maintain the equine-1 hemagglutinin in its native form in infected cells. Virology. 202: 1007-11. PMID 7518161 DOI: 10.1006/Viro.1994.1428  0.517
1994 Holsinger LJ, Nichani D, Pinto LH, Lamb RA. Influenza A virus M2 ion channel protein: a structure-function analysis. Journal of Virology. 68: 1551-63. PMID 7508997 DOI: 10.1128/Jvi.68.3.1551-1563.1994  0.428
1994 Takeuchi K, Lamb RA. Influenza virus M2 protein ion channel activity stabilizes the native form of fowl plague virus hemagglutinin during intracellular transport. Journal of Virology. 68: 911-9. PMID 7507186 DOI: 10.1128/Jvi.68.2.911-919.1994  0.515
1994 Lamb RA, Holsinger LJ, Pinto LH. 16 The Influenza A Virus M2 Ion Channel Protein and Its Role in the Influenza Virus Life Cycle Cold Spring Harbor Monograph Archive. 28: 303-321. DOI: 10.1101/087969429.28.303  0.553
1993 Doms RW, Lamb RA, Rose JK, Helenius A. Folding and assembly of viral membrane proteins. Virology. 193: 545-62. PMID 8460475 DOI: 10.1006/Viro.1993.1164  0.375
1993 Parks GD, Lamb RA. Role of NH2-terminal positively charged residues in establishing membrane protein topology. The Journal of Biological Chemistry. 268: 19101-9. PMID 8103052  0.304
1993 Wang C, Takeuchi K, Pinto LH, Lamb RA. Ion channel activity of influenza A virus M2 protein: characterization of the amantadine block. Journal of Virology. 67: 5585-94. PMID 7688826 DOI: 10.1128/Jvi.67.9.5585-5594.1993  0.481
1992 Horvath CM, Paterson RG, Shaughnessy MA, Wood R, Lamb RA. Biological activity of paramyxovirus fusion proteins: factors influencing formation of syncytia. Journal of Virology. 66: 4564-9. PMID 1602561 DOI: 10.1128/Jvi.66.7.4564-4569.1992  0.569
1992 Ng DT, Watowich SS, Lamb RA. Analysis in vivo of GRP78-BiP/substrate interactions and their role in induction of the GRP78-BiP gene. Molecular Biology of the Cell. 3: 143-55. PMID 1550958 DOI: 10.1091/Mbc.3.2.143  0.765
1992 Horvath CM, Lamb RA. Studies on the fusion peptide of a paramyxovirus fusion glycoprotein: roles of conserved residues in cell fusion. Journal of Virology. 66: 2443-55. PMID 1548771 DOI: 10.1128/Jvi.66.4.2443-2455.1992  0.509
1992 Hughey PG, Compans RW, Zebedee SL, Lamb RA. Expression of the influenza A virus M2 protein is restricted to apical surfaces of polarized epithelial cells. Journal of Virology. 66: 5542-52. PMID 1501289 DOI: 10.1128/Jvi.66.9.5542-5552.1992  0.564
1992 Pinto LH, Holsinger LJ, Lamb RA. Influenza virus M2 protein has ion channel activity. Cell. 69: 517-28. PMID 1374685 DOI: 10.1016/0092-8674(92)90452-I  0.491
1992 Parks GD, Ward CD, Lamb RA. Molecular cloning of the NP and L genes of simian virus 5: identification of highly conserved domains in paramyxovirus NP and L proteins. Virus Research. 22: 259-79. PMID 1320792 DOI: 10.1016/0168-1702(92)90057-G  0.408
1992 Simpson DA, Lamb RA. Alterations to influenza virus hemagglutinin cytoplasmic tail modulate virus infectivity. Journal of Virology. 66: 790-803. PMID 1309913 DOI: 10.1128/Jvi.66.2.790-803.1992  0.545
1991 Holsinger LJ, Lamb RA. Influenza virus M2 integral membrane protein is a homotetramer stabilized by formation of disulfide bonds. Virology. 183: 32-43. PMID 2053285  0.424
1991 Watowich SS, Morimoto RI, Lamb RA. Flux of the paramyxovirus hemagglutinin-neuraminidase glycoprotein through the endoplasmic reticulum activates transcription of the GRP78-BiP gene. Journal of Virology. 65: 3590-7. PMID 2041085 DOI: 10.1128/Jvi.65.7.3590-3597.1991  0.529
1991 Parks GD, Lamb RA. Topology of eukaryotic type II membrane proteins: importance of N-terminal positively charged residues flanking the hydrophobic domain. Cell. 64: 777-87. PMID 1997206 DOI: 10.1016/0092-8674(91)90507-U  0.368
1991 Simpson DA, Lamb RA. Influenza virus ts61S hemagglutinin is significantly defective in polypeptide folding and intracellular transport at the permissive temperature. Virology. 185: 477-83. PMID 1926789 DOI: 10.1016/0042-6822(91)90803-J  0.426
1991 Sheshberadaran H, Lamb RA. Simian virus 5 membrane protein maturation: expression in virus-infected cells and from a eukaryotic vector. Virology. 183: 803-9. PMID 1853577 DOI: 10.1016/0042-6822(91)91015-9  0.511
1991 Lamb RA, Horvath CM. Diversity of coding strategies in influenza viruses. Trends in Genetics : Tig. 7: 261-6. PMID 1771674 DOI: 10.1016/0168-9525(91)90326-L  0.403
1990 Sheshberadaran H, Lamb RA. Sequence characterization of the membrane protein gene of paramyxovirus simian virus 5. Virology. 176: 234-43. PMID 2330672 DOI: 10.1016/0042-6822(90)90248-P  0.408
1990 Paterson RG, Lamb RA. Conversion of a class II integral membrane protein into a soluble and efficiently secreted protein: multiple intracellular and extracellular oligomeric and conformational forms. The Journal of Cell Biology. 110: 999-1011. PMID 2324203 DOI: 10.1083/Jcb.110.4.999  0.433
1990 Treanor JJ, Tierney EL, Zebedee SL, Lamb RA, Murphy BR. Passively transferred monoclonal antibody to the M2 protein inhibits influenza A virus replication in mice. Journal of Virology. 64: 1375-7. PMID 2304147 DOI: 10.1128/Jvi.64.3.1375-1377.1990  0.541
1990 Parks GD, Lamb RA. Folding and oligomerization properties of a soluble and secreted form of the paramyxovirus hemagglutinin-neuraminidase glycoprotein. Virology. 178: 498-508. PMID 2219705 DOI: 10.1016/0042-6822(90)90347-T  0.489
1990 Ng DT, Hiebert SW, Lamb RA. Different roles of individual N-linked oligosaccharide chains in folding, assembly, and transport of the simian virus 5 hemagglutinin-neuraminidase. Molecular and Cellular Biology. 10: 1989-2001. PMID 2183015 DOI: 10.1128/Mcb.10.5.1989  0.812
1990 Paterson RG, Lamb RA. RNA editing by G-nucleotide insertion in mumps virus P-gene mRNA transcripts. Journal of Virology. 64: 4137-45. PMID 2166809 DOI: 10.1128/Jvi.64.9.4137-4145.1990  0.395
1990 Parks GD, Lamb RA. Defective assembly and intracellular transport of mutant paramyxovirus hemagglutinin-neuraminidase proteins containing altered cytoplasmic domains. Journal of Virology. 64: 3605-16. PMID 2164588 DOI: 10.1128/Jvi.64.8.3605-3616.1990  0.481
1990 Horvath CM, Williams MA, Lamb RA. Eukaryotic coupled translation of tandem cistrons: identification of the influenza B virus BM2 polypeptide. The Embo Journal. 9: 2639-47. PMID 2114979 DOI: 10.1002/J.1460-2075.1990.Tb07446.X  0.551
1989 Zebedee SL, Lamb RA. Growth restriction of influenza A virus by M2 protein antibody is genetically linked to the M1 protein. Proceedings of the National Academy of Sciences of the United States of America. 86: 1061-5. PMID 2915973 DOI: 10.1073/Pnas.86.3.1061  0.482
1989 Williams MA, Lamb RA. Effect of mutations and deletions in a bicistronic mRNA on the synthesis of influenza B virus NB and NA glycoproteins. Journal of Virology. 63: 28-35. PMID 2908923 DOI: 10.1128/Jvi.63.1.28-35.1989  0.443
1989 Zebedee SL, Lamb RA. Nucleotide sequences of influenza A virus RNA segment 7: a comparison of five isolates. Nucleic Acids Research. 17: 2870. PMID 2701939 DOI: 10.1093/Nar/17.7.2870  0.446
1989 Paterson RG, Shaughnessy MA, Lamb RA. Analysis of the relationship between cleavability of a paramyxovirus fusion protein and length of the connecting peptide. Journal of Virology. 63: 1293-301. PMID 2644448 DOI: 10.1128/Jvi.63.3.1293-1301.1989  0.453
1989 Ng DT, Randall RE, Lamb RA. Intracellular maturation and transport of the SV5 type II glycoprotein hemagglutinin-neuraminidase: specific and transient association with GRP78-BiP in the endoplasmic reticulum and extensive internalization from the cell surface. The Journal of Cell Biology. 109: 3273-89. PMID 2557352 DOI: 10.1083/Jcb.109.6.3273  0.77
1989 Parks GD, Hull JD, Lamb RA. Transposition of domains between the M2 and HN viral membrane proteins results in polypeptides which can adopt more than one membrane orientation. The Journal of Cell Biology. 109: 2023-32. PMID 2553741 DOI: 10.1083/Jcb.109.5.2023  0.449
1988 Williams MA, Lamb RA. Polylactosaminoglycan modification of a small integral membrane glycoprotein, influenza B virus NB. Molecular and Cellular Biology. 8: 1186-96. PMID 3367907 DOI: 10.1128/Mcb.8.3.1186  0.517
1988 Hiebert SW, Lamb RA. Cell surface expression of glycosylated, nonglycosylated, and truncated forms of a cytoplasmic protein pyruvate kinase. The Journal of Cell Biology. 107: 865-76. PMID 3047152 DOI: 10.1083/Jcb.107.3.865  0.602
1988 Thomas SM, Lamb RA, Paterson RG. Two mRNAs that differ by two nontemplated nucleotides encode the amino coterminal proteins P and V of the paramyxovirus SV5. Cell. 54: 891-902. PMID 3044614 DOI: 10.1016/S0092-8674(88)91285-8  0.346
1988 Hiebert SW, Richardson CD, Lamb RA. Cell surface expression and orientation in membranes of the 44-amino-acid SH protein of simian virus 5. Journal of Virology. 62: 2347-57. PMID 2836617 DOI: 10.1128/Jvi.62.7.2347-2357.1988  0.649
1988 Hull JD, Gilmore R, Lamb RA. Integration of a small integral membrane protein, M2, of influenza virus into the endoplasmic reticulum: analysis of the internal signal-anchor domain of a protein with an ectoplasmic NH2 terminus. The Journal of Cell Biology. 106: 1489-98. PMID 2836432 DOI: 10.1083/Jcb.106.5.1489  0.474
1988 Zebedee SL, Lamb RA. Influenza A virus M2 protein: monoclonal antibody restriction of virus growth and detection of M2 in virions. Journal of Virology. 62: 2762-72. PMID 2455818 DOI: 10.1128/Jvi.62.8.2762-2772.1988  0.487
1988 Lamb RA, Hiebert SW, Hull J, Ng D, Williams MA, Zebedee SL. Structure, modification, intracellular transport and function of influenza and paramyxovirus integral membrane proteins Virus Research. 11: 10. DOI: 10.1016/0168-1702(88)90116-5  0.779
1988 Paterson RG, Lamb RA. Studies on the structure and function of the SV5 fusion protein Virus Research. 11: 5. DOI: 10.1016/0168-1702(88)90107-4  0.372
1987 Paterson RG, Lamb RA, Moss B, Murphy BR. Comparison of the relative roles of the F and HN surface glycoproteins of the paramyxovirus simian virus 5 in inducing protective immunity. Journal of Virology. 61: 1972-7. PMID 3573154 DOI: 10.1128/Jvi.61.6.1972-1977.1987  0.512
1987 Paterson RG, Lamb RA. Ability of the hydrophobic fusion-related external domain of a paramyxovirus F protein to act as a membrane anchor. Cell. 48: 441-52. PMID 3026647 DOI: 10.1016/0092-8674(87)90195-4  0.465
1986 Hiebert SW, Williams MA, Lamb RA. Nucleotide sequence of RNA segment 7 of influenza B/Singapore/222/79: maintenance of a second large open reading frame. Virology. 155: 747-51. PMID 3788064 DOI: 10.1016/0042-6822(86)90237-0  0.608
1986 Nicholson AW, Frankfort HM, Davis NG, Ferrari S, Lamb RA, Robertson HD. Direct characterization of influenza viral NS1 mRNA and related sequences from infected HeLa cells and a cell-free transcription system. Biochimica Et Biophysica Acta. 868: 153-63. PMID 3094582 DOI: 10.1016/0167-4781(86)90018-7  0.452
1986 Williams MA, Lamb RA. Determination of the orientation of an integral membrane protein and sites of glycosylation by oligonucleotide-directed mutagenesis: influenza B virus NB glycoprotein lacks a cleavable signal sequence and has an extracellular NH2-terminal region. Molecular and Cellular Biology. 6: 4317-28. PMID 3025652 DOI: 10.1128/Mcb.6.12.4317  0.527
1985 Hiebert SW, Paterson RG, Lamb RA. Identification and predicted sequence of a previously unrecognized small hydrophobic protein, SH, of the paramyxovirus simian virus 5. Journal of Virology. 55: 744-51. PMID 4020965 DOI: 10.1128/Jvi.55.3.744-751.1985  0.66
1985 Hiebert SW, Paterson RG, Lamb RA. Hemagglutinin-neuraminidase protein of the paramyxovirus simian virus 5: nucleotide sequence of the mRNA predicts an N-terminal membrane anchor. Journal of Virology. 54: 1-6. PMID 3973974 DOI: 10.1128/Jvi.54.1.1-6.1985  0.661
1985 Lamb RA, Zebedee SL, Richardson CD. Influenza virus M2 protein is an integral membrane protein expressed on the infected-cell surface. Cell. 40: 627-33. PMID 3882238 DOI: 10.1016/0092-8674(85)90211-9  0.561
1985 Paterson RG, Hiebert SW, Lamb RA. Expression at the cell surface of biologically active fusion and hemagglutinin/neuraminidase proteins of the paramyxovirus simian virus 5 from cloned cDNA. Proceedings of the National Academy of Sciences of the United States of America. 82: 7520-4. PMID 3865176 DOI: 10.1073/Pnas.82.22.7520  0.742
1985 Zebedee SL, Richardson CD, Lamb RA. Characterization of the influenza virus M2 integral membrane protein and expression at the infected-cell surface from cloned cDNA. Journal of Virology. 56: 502-11. PMID 3840537 DOI: 10.1128/Jvi.56.2.502-511.1985  0.543
1985 Paterson RG, Hiebert SW, Lamb RA. Expression of biologically active F and HN proteins of the paramyxovirus SV5 from cloned cDNA Virus Research. 3: 6. DOI: 10.1016/0168-1702(85)90265-5  0.658
1984 Paterson RG, Harris TJ, Lamb RA. Analysis and gene assignment of mRNAs of a paramyxovirus, simian virus 5. Virology. 138: 310-23. PMID 6548594 DOI: 10.1016/0042-6822(84)90354-4  0.416
1984 Shaw MW, Lamb RA. A specific sub-set of host-cell mRNAs prime influenza virus mRNA synthesis. Virus Research. 1: 455-67. PMID 6532008 DOI: 10.1016/0168-1702(84)90003-0  0.477
1984 Lamb RA, Lai CJ. Expression of unspliced NS1 mRNA, spliced NS2 mRNA, and a spliced chimera mRNA from cloned influenza virus NS DNA in an SV40 vector. Virology. 135: 139-47. PMID 6328745 DOI: 10.1016/0042-6822(84)90124-7  0.437
1984 Paterson RG, Harris TJ, Lamb RA. Fusion protein of the paramyxovirus simian virus 5: nucleotide sequence of mRNA predicts a highly hydrophobic glycoprotein. Proceedings of the National Academy of Sciences of the United States of America. 81: 6706-10. PMID 6093114 DOI: 10.1073/Pnas.81.21.6706  0.473
1983 Strickland S, Lamb RA. Infection of mouse teratocarcinoma stem cells with influenza virus: normal expression of proteins derived from spliced messenger RNAs. Developmental Biology. 97: 506-9. PMID 6852378 DOI: 10.1016/0012-1606(83)90108-2  0.494
1983 Lamb RA, Choppin PW. The gene structure and replication of influenza virus. Annual Review of Biochemistry. 52: 467-506. PMID 6351727 DOI: 10.1146/Annurev.Bi.52.070183.002343  0.671
1983 Shaw MW, Choppin PW, Lamb RA. A previously unrecognized influenza B virus glycoprotein from a bicistronic mRNA that also encodes the viral neuraminidase. Proceedings of the National Academy of Sciences of the United States of America. 80: 4879-83. PMID 6308656 DOI: 10.1073/Pnas.80.16.4879  0.706
1982 Shaw MW, Lamb RA, Erickson BW, Briedis DJ, Choppin PW. Complete nucleotide sequence of the neuraminidase gene of influenza B virus. Proceedings of the National Academy of Sciences of the United States of America. 79: 6817-21. PMID 6294654 DOI: 10.1073/Pnas.79.22.6817  0.716
1982 Briedis DJ, Lamb RA. Influenza B virus genome: sequences and structural organization of RNA segment 8 and the mRNAs coding for the NS1 and NS2 proteins. Journal of Virology. 42: 186-93. PMID 6283137 DOI: 10.1128/Jvi.42.1.186-193.1982  0.459
1982 Briedis DJ, Lamb RA, Choppin PW. Sequence of RNA segment 7 of the influenza B virus genome: partial amino acid homology between the membrane proteins (M1) of influenza A and B viruses and conservation of a second open reading frame. Virology. 116: 581-8. PMID 6278729 DOI: 10.1016/0042-6822(82)90150-7  0.715
1982 Lamb RA, Lai CJ. Spliced and unspliced messenger RNAs synthesized from cloned influenza virus M DNA in an SV40 vector: expression of the influenza virus membrane protein (M1). Virology. 123: 237-56. PMID 6184879 DOI: 10.1016/0042-6822(82)90258-6  0.522
1981 Lamb RA, Lai CJ. Conservation of the influenza virus membrane protein (M1) amino acid sequence and an open reading frame of RNA segment 7 encoding a second protein (M2) in H1N1 and H3N2 strains. Virology. 112: 746-51. PMID 7257189 DOI: 10.1016/0042-6822(81)90319-6  0.449
1981 Lamb RA, Choppin PW. Identification of a second protein (M2) encoded by RNA segment 7 of influenza virus. Virology. 112: 729-37. PMID 7257188 DOI: 10.1016/0042-6822(81)90317-2  0.679
1981 Briedis DJ, Lamb RA, Choppin PW. Influenza B virus RNA segment 8 codes for two nonstructural proteins. Virology. 112: 417-25. PMID 7257181 DOI: 10.1016/0042-6822(81)90289-0  0.67
1981 Lamb RA, Lai CJ, Choppin PW. Sequences of mRNAs derived from genome RNA segment 7 of influenza virus: colinear and interrupted mRNAs code for overlapping proteins. Proceedings of the National Academy of Sciences of the United States of America. 78: 4170-4. PMID 6945577 DOI: 10.1073/Pnas.78.7.4170  0.622
1980 Lamb RA, Lai CJ. Sequence of interrupted and uninterrupted mRNAs and cloned DNA coding for the two overlapping nonstructural proteins of influenza virus. Cell. 21: 475-85. PMID 7407920 DOI: 10.1016/0092-8674(80)90484-5  0.377
1980 Hall WW, Lamb RA, Choppin PW. The polypeptides of canine distemper virus: synthesis in infected cells and relatedness to the polypeptides of other morbilliviruses. Virology. 100: 433-49. PMID 7352374 DOI: 10.1016/0042-6822(80)90534-6  0.693
1980 Lai CJ, Markoff LJ, Sveda MM, Lamb RA, Dhar R, Chanock RM. Genetic variation of influenza A viruses as studied by recombinant DNA techniques. Annals of the New York Academy of Sciences. 354: 162-71. PMID 6261643 DOI: 10.1111/J.1749-6632.1980.Tb27965.X  0.361
1980 Lamb RA, Choppin PW, Chanock RM, Lai CJ. Mapping of the two overlapping genes for polypeptides NS1 and NS2 on RNA segment 8 of influenza virus genome. Proceedings of the National Academy of Sciences of the United States of America. 77: 1857-61. PMID 6246509 DOI: 10.1073/Pnas.77.4.1857  0.611
1980 Etkind PR, Cross RK, Lamb RA, Merz DC, Choppin PW. In vitro synthesis of structural and nonstructural proteins of Sendai and SV5 viruses. Virology. 100: 22-33. PMID 6243200 DOI: 10.1016/0042-6822(80)90548-6  0.695
1980 Lamb RA, Choppin PW. A ninth unique influenza virus-coded polypeptide. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 288: 327-33. PMID 6103549 DOI: 10.1098/Rstb.1980.0008  0.694
1979 Lamb RA, Choppin PW. Segment 8 of the influenza virus genome is unique in coding for two polypeptides. Proceedings of the National Academy of Sciences of the United States of America. 76: 4908-12. PMID 291907 DOI: 10.1073/Pnas.76.10.4908  0.702
1979 Hall WW, Lamb RA, Choppin PW. Measles and subacute sclerosing panencephalitis virus proteins: lack of antibodies to the M protein in patients with subacute sclerosing panencephalitis. Proceedings of the National Academy of Sciences of the United States of America. 76: 2047-51. PMID 287042 DOI: 10.1073/Pnas.76.4.2047  0.672
1978 Lamb RA, Etkind PR, Choppin PW. Evidence for a ninth influenza viral polypeptide. Virology. 91: 60-78. PMID 726267 DOI: 10.1016/0042-6822(78)90355-0  0.688
1978 Peluso RW, Lamb RA, Choppin PW. Infection with paramyxoviruses stimulates synthesis of cellular polypeptides that are also stimulated in cells transformed by Rous sarcoma virus or deprived of glucose. Proceedings of the National Academy of Sciences of the United States of America. 75: 6120-4. PMID 216013 DOI: 10.1073/Pnas.75.12.6120  0.629
1978 Lamb RA, Choppin PW. Determination by peptide mapping of the unique polypeptides in Sendai virions and infected cells. Virology. 84: 469-78. PMID 203096 DOI: 10.1016/0042-6822(78)90263-5  0.651
1977 Lamb RA, Choppin PW. Synthesis of influenza virus polypeptides in cells resistant to alpha-amanitin: evidence for the involvement of cellular RNA polymerase II in virus replication. Journal of Virology. 23: 816-9. PMID 561196 DOI: 10.1128/Jvi.23.3.816-819.1977  0.688
1977 Lamb RA, Choppin PW. The synthesis of Sendai virus polypeptides in infected cells. III. Phosphorylation of polypeptides. Virology. 81: 382-97. PMID 197698 DOI: 10.1016/0042-6822(77)90154-4  0.654
1977 Lamb RA, Choppin PW. The synthesis of Sendai virus polypeptides in infected cells. II. Intracellular distribution of polypeptides. Virology. 81: 371-81. PMID 197697 DOI: 10.1016/0042-6822(77)90153-2  0.676
1977 Peluso RW, Lamb RA, Choppin PW. Polypeptide synthesis in simian virus 5-infected cells. Journal of Virology. 23: 177-87. PMID 196101 DOI: 10.1128/Jvi.23.1.177-187.1977  0.696
1976 Lamb RA, Choppin PW. Synthesis of influenza virus proteins in infected cells: translation of viral polypeptides, including three P polypeptides, from RNA produced by primary transcription. Virology. 74: 504-19. PMID 982840 DOI: 10.1016/0042-6822(76)90356-1  0.698
1976 Inglis SC, Carroll AR, Lamb RA, Mahy BW. Polypeptides specified by the influenza virus genome I. Evidence for eight distinct gene products specified by fowl plague virus. Virology. 74: 489-503. PMID 982839 DOI: 10.1016/0042-6822(76)90355-X  0.726
1976 Lamb RA, Mahy BW, Choppin PW. The synthesis of sendai virus polypeptides in infected cells. Virology. 69: 116-31. PMID 174287 DOI: 10.1016/0042-6822(76)90199-9  0.793
1975 Lamb RA. The phosphorylation of sendai virus proteins by a virus particle-associated protein kinase. The Journal of General Virology. 26: 249-63. PMID 235597 DOI: 10.1099/0022-1317-26-3-249  0.467
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