William J. Steinbach - Publications

Affiliations: 
Pediatrics Duke Medical School, Durham, NC, United States 

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Juvvadi PR, Bobay BG, Cole DC, Awwa M, Steinbach WJ. Calcineurin Inhibitor CN585 Exhibits Off-Target Effects in the Human Fungal Pathogen . Journal of Fungi (Basel, Switzerland). 8. PMID 36547614 DOI: 10.3390/jof8121281  0.302
2022 Shwab EK, Juvvadi PR, Shaheen SK, Allen J, Waitt G, Soderblom EJ, Asfaw YG, Moseley MA, Steinbach WJ. Protein Kinase A Regulates Autophagy-Associated Proteins Impacting Growth and Virulence of . Journal of Fungi (Basel, Switzerland). 8. PMID 35448585 DOI: 10.3390/jof8040354  0.399
2020 Shwab EK, Juvvadi PR, Waitt G, Shaheen S, Allen J, Soderblom EJ, Bobay BG, Asfaw YG, Moseley MA, Steinbach WJ. The Protein Kinase A-Dependent Phosphoproteome of the Human Pathogen Aspergillus fumigatus Reveals Diverse Virulence-Associated Kinase Targets. Mbio. 11. PMID 33323509 DOI: 10.1128/mBio.02880-20  0.365
2020 Renshaw H, Juvvadi PR, Cole DC, Steinbach WJ. The class V myosin interactome of the human pathogen Aspergillus fumigatus reveals novel interactions with COPII vesicle transport proteins. Biochemical and Biophysical Research Communications. 527: 232-237. PMID 32446373 DOI: 10.1016/j.bbrc.2020.04.111  0.333
2019 Juvvadi PR, Fox D, Bobay BG, Hoy MJ, Gobeil SMC, Venters RA, Chang Z, Lin JJ, Averette AF, Cole DC, Barrington BC, Wheaton JD, Ciofani M, Trzoss M, Li X, ... ... Steinbach WJ, et al. Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents. Nature Communications. 10: 4275. PMID 31537789 DOI: 10.1038/S41467-019-12199-1  0.304
2019 Shwab EK, Juvvadi PR, Waitt G, Soderblom EJ, Barrington BC, Asfaw YG, Moseley MA, Steinbach WJ. Calcineurin-dependent dephosphorylation of the transcription factor CrzA at specific sites controls conidiation, stress tolerance, and virulence of Aspergillus fumigatus. Molecular Microbiology. PMID 30927289 DOI: 10.1111/mmi.14254  0.309
2018 Juvvadi PR, Cole DC, Falloon K, Waitt G, Soderblom EJ, Moseley MA, Steinbach WJ. Kin1 kinase localizes at the hyphal septum and is dephosphorylated by calcineurin but is dispensable for septation and virulence in the human pathogen Aspergillus fumigatus. Biochemical and Biophysical Research Communications. 505: 740-746. PMID 30292408 DOI: 10.1016/j.bbrc.2018.09.186  0.457
2017 Renshaw H, Vargas-Muñiz JM, Juvvadi PR, Richards AD, Waitt G, Soderblom EJ, Moseley MA, Steinbach WJ. Tail domain of the Aspergillus fumigatus class V myosin orchestrates septal localization and hyphal growth. Journal of Cell Science. PMID 29222113 DOI: 10.1242/jcs.205955  0.726
2017 Shwab EK, Juvvadi PR, Waitt G, Soderblom EJ, Moseley MA, Nicely NI, Steinbach WJ. Phosphorylation of Aspergillus fumigatus PkaR Impacts Growth and Cell Wall Integrity Through Novel Mechanisms. Febs Letters. PMID 29067690 DOI: 10.1002/1873-3468.12886  0.354
2017 Vargas-Muñiz JM, Renshaw H, Waitt G, Soderblom EJ, Moseley MA, Palmer JM, Juvvadi PR, Keller NP, Steinbach WJ. Caspofungin exposure alters the core septin AspB interactome of Aspergillus fumigatus. Biochemical and Biophysical Research Communications. PMID 28238781 DOI: 10.1016/J.Bbrc.2017.02.116  0.707
2017 Shwab EK, Juvvadi PR, Waitt G, Soderblom EJ, Moseley MA, Nicely NI, Asfaw YG, Steinbach WJ. A Novel Phosphoregulatory Switch Controls the Activity and Function of the Major Catalytic Subunit of Protein Kinase A in Aspergillus fumigatus. Mbio. 8. PMID 28174315 DOI: 10.1128/mBio.02319-16  0.359
2016 Vargas-Muñiz JM, Juvvadi PR, Steinbach WJ. Forging the ring: from fungal septins' divergent roles in morphology, septation and virulence to factors contributing to their assembly into higher order structures. Microbiology (Reading, England). 162: 1527-1534. PMID 27559018 DOI: 10.1099/mic.0.000359  0.719
2016 Vargas-Muñiz JM, Renshaw H, Richards AD, Waitt G, Soderblom EJ, Moseley MA, Asfaw Y, Juvvadi PR, Steinbach WJ. Dephosphorylation of the Core Septin, AspB, in a Protein Phosphatase 2A-Dependent Manner Impacts Its Localization and Function in the Fungal Pathogen Aspergillus fumigatus. Frontiers in Microbiology. 7: 997. PMID 27446037 DOI: 10.3389/fmicb.2016.00997  0.735
2016 Renshaw H, Vargas-Muñiz JM, Richards AD, Asfaw YG, Juvvadi PR, Steinbach WJ. Distinct Roles of Myosins in Aspergillus fumigatus Hyphal Growth and Pathogenesis. Infection and Immunity. 84: 1556-64. PMID 26953327 DOI: 10.1128/IAI.01190-15  0.742
2015 Juvvadi PR, Steinbach WJ. Calcineurin Orchestrates Hyphal Growth, Septation, Drug Resistance and Pathogenesis of Aspergillus fumigatus: Where Do We Go from Here? Pathogens (Basel, Switzerland). 4: 883-93. PMID 26694470 DOI: 10.3390/pathogens4040883  0.309
2015 Falloon K, Juvvadi PR, Richards AD, Vargas-Muñiz JM, Renshaw H, Steinbach WJ. Characterization of the FKBP12-Encoding Genes in Aspergillus fumigatus. Plos One. 10: e0137869. PMID 26366742 DOI: 10.1371/journal.pone.0137869  0.74
2015 Vargas-Muñiz JM, Renshaw H, Richards AD, Lamoth F, Soderblom EJ, Moseley MA, Juvvadi PR, Steinbach WJ. The Aspergillus fumigatus septins play pleiotropic roles in septation, conidiation, and cell wall stress, but are dispensable for virulence. Fungal Genetics and Biology : Fg & B. 81: 41-51. PMID 26051489 DOI: 10.1016/j.fgb.2015.05.014  0.743
2015 Juvvadi PR, Ma Y, Richards AD, Soderblom EJ, Moseley MA, Lamoth F, Steinbach WJ. Identification and mutational analyses of phosphorylation sites of the calcineurin-binding protein CbpA and the identification of domains required for calcineurin binding in Aspergillus fumigatus. Frontiers in Microbiology. 6: 175. PMID 25821446 DOI: 10.3389/fmicb.2015.00175  0.309
2014 Juvvadi PR, Lamoth F, Steinbach WJ. Calcineurin as a Multifunctional Regulator: Unraveling Novel Functions in Fungal Stress Responses, Hyphal Growth, Drug Resistance, and Pathogenesis. Fungal Biology Reviews. 28: 56-69. PMID 25383089 DOI: 10.1016/j.fbr.2014.02.004  0.31
2014 Juvvadi PR, Lamoth F, Steinbach WJ. Calcineurin-mediated regulation of hyphal growth, septation, and virulence in Aspergillus fumigatus. Mycopathologia. 178: 341-8. PMID 25118871 DOI: 10.1007/s11046-014-9794-9  0.458
2013 Juvvadi PR, Gehrke C, Fortwendel JR, Lamoth F, Soderblom EJ, Cook EC, Hast MA, Asfaw YG, Moseley MA, Creamer TP, Steinbach WJ. Phosphorylation of Calcineurin at a novel serine-proline rich region orchestrates hyphal growth and virulence in Aspergillus fumigatus. Plos Pathogens. 9: e1003564. PMID 23990785 DOI: 10.1371/Journal.Ppat.1003564  0.417
2013 Juvvadi PR, Belina D, Soderblom EJ, Moseley MA, Steinbach WJ. Filamentous fungal-specific septin AspE is phosphorylated in vivo and interacts with actin, tubulin and other septins in the human pathogen Aspergillus fumigatus. Biochemical and Biophysical Research Communications. 431: 547-53. PMID 23321313 DOI: 10.1016/j.bbrc.2013.01.020  0.375
2011 Juvvadi PR, Fortwendel JR, Rogg LE, Burns KA, Randell SH, Steinbach WJ. Localization and activity of the calcineurin catalytic and regulatory subunit complex at the septum is essential for hyphal elongation and proper septation in Aspergillus fumigatus. Molecular Microbiology. 82: 1235-59. PMID 22066998 DOI: 10.1111/j.1365-2958.2011.07886.x  0.437
2011 Rogg LE, Fortwendel JR, Juvvadi PR, Lilley A, Steinbach WJ. The chitin synthase genes chsA and chsC are not required for cell wall stress responses in the human pathogen Aspergillus fumigatus Biochemical and Biophysical Research Communications. 411: 549-554. PMID 21763289 DOI: 10.1016/j.bbrc.2011.06.180  0.366
2011 Juvvadi PR, Fortwendel JR, Rogg LE, Steinbach WJ. Differential localization patterns of septins during growth of the human fungal pathogen Aspergillus fumigatus reveal novel functions. Biochemical and Biophysical Research Communications. 405: 238-43. PMID 21219860 DOI: 10.1016/j.bbrc.2011.01.017  0.363
2010 Fortwendel JR, Juvvadi PR, Perfect BZ, Rogg LE, Perfect JR, Steinbach WJ. Transcriptional regulation of chitin synthases by calcineurin controls paradoxical growth of Aspergillus fumigatus in response to caspofungin. Antimicrobial Agents and Chemotherapy. 54: 1555-63. PMID 20124000 DOI: 10.1128/AAC.00854-09  0.384
2009 Pinchai N, Perfect BZ, Juvvadi PR, Fortwendel JR, Cramer RA, Asfaw YG, Heitman J, Perfect JR, Steinbach WJ. Aspergillus fumigatus calcipressin CbpA is involved in hyphal growth and calcium homeostasis. Eukaryotic Cell. 8: 511-9. PMID 19252123 DOI: 10.1128/Ec.00336-08  0.354
2009 Fortwendel JR, Juvvadi PR, Pinchai N, Perfect BZ, Alspaugh JA, Perfect JR, Steinbach WJ. Differential effects of inhibiting chitin and 1,3-{beta}-D-glucan synthesis in ras and calcineurin mutants of Aspergillus fumigatus. Antimicrobial Agents and Chemotherapy. 53: 476-82. PMID 19015336 DOI: 10.1128/AAC.01154-08  0.326
2008 Cramer RA, Perfect BZ, Pinchai N, Park S, Perlin DS, Asfaw YG, Heitman J, Perfect JR, Steinbach WJ. Calcineurin target CrzA regulates conidial germination, hyphal growth, and pathogenesis of Aspergillus fumigatus. Eukaryotic Cell. 7: 1085-97. PMID 18456861 DOI: 10.1128/Ec.00086-08  0.425
2006 Steinbach WJ, Cramer RA, Perfect BZ, Asfaw YG, Sauer TC, Najvar LK, Kirkpatrick WR, Patterson TF, Benjamin DK, Heitman J, Perfect JR. Calcineurin controls growth, morphology, and pathogenicity in Aspergillus fumigatus. Eukaryotic Cell. 5: 1091-103. PMID 16835453 DOI: 10.1128/Ec.00139-06  0.401
2006 Cramer RA, Gamcsik MP, Brooking RM, Najvar LK, Kirkpatrick WR, Patterson TF, Balibar CJ, Graybill JR, Perfect JR, Abraham SN, Steinbach WJ. Disruption of a nonribosomal peptide synthetase in Aspergillus fumigatus eliminates gliotoxin production. Eukaryotic Cell. 5: 972-80. PMID 16757745 DOI: 10.1128/Ec.00049-06  0.324
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