Michael Tymianski, M.D., Ph.D. - Publications

Affiliations: 
Neurosurgery Toronto Western Hospital, University of Toronto 
Area:
Stroke, NMDA receptors, TRP channels

82 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Hill MD, Goyal M, Menon BK, Nogueira RG, McTaggart RA, Demchuk AM, Poppe AY, Buck BH, Field TS, Dowlatshahi D, van Adel BA, Swartz RH, Shah RA, Sauvageau E, Zerna C, ... ... Tymianski M, et al. Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial. Lancet (London, England). PMID 32087818 DOI: 10.1016/S0140-6736(20)30258-0  0.362
2019 Gondard E, Teves L, Wang L, McKinnon C, Hamani C, Kalia SK, Carlen PL, Tymianski M, Lozano AM. Deep Brain Stimulation rescues memory and synaptic activity in a rat model of global ischemia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30696731 DOI: 10.1523/Jneurosci.1222-18.2019  0.347
2019 Sun X, Garman D, Tymianski M. Abstract 80: The Experimental Neuroprotective Drug Na1 Does Not Interfere With the Fibrinolytic Activities of Alteplase or Tenecteplase Stroke. 50. DOI: 10.1161/Str.50.Suppl_1.80  0.339
2019 Ballarin B, Cui H, Teves LM, Ji Z, Tymianski M. Abstract 25: Promoting Recovery After Stroke by Manipulating NMDA Receptor-Associated Signalling in the Early Post Stroke Phase Stroke. 50. DOI: 10.1161/Str.50.Suppl_1.25  0.411
2018 Bernhardt J, Zorowitz RD, Becker KJ, Keller E, Saposnik G, Strbian D, Dichgans M, Woo D, Reeves M, Thrift A, Kidwell CS, Olivot JM, Goyal M, Pierot L, Bennett DA, ... ... Tymianski M, et al. Advances in Stroke 2017. Stroke. PMID 29669874 DOI: 10.1161/Strokeaha.118.021380  0.326
2018 Ballarin B, Tymianski M. Discovery and development of NA-1 for the treatment of acute ischemic stroke. Acta Pharmacologica Sinica. 39: 661-668. PMID 29565039 DOI: 10.1038/Aps.2018.5  0.413
2018 Wu QJ, Tymianski M. Targeting NMDA receptors in stroke: new hope in neuroprotection. Molecular Brain. 11: 15. PMID 29534733 DOI: 10.1186/S13041-018-0357-8  0.497
2017 Mayor D, Tymianski M. Neurotransmitters in the mediation of cerebral ischemic injury. Neuropharmacology. 134: 178-188. PMID 29203179 DOI: 10.1016/J.Neuropharm.2017.11.050  0.441
2017 Bosetti F, Koenig JI, Ayata C, Back SA, Becker K, Broderick JP, Carmichael ST, Cho S, Cipolla MJ, Corbett D, Corriveau RA, Cramer SC, Ferguson AR, Finklestein SP, Ford BD, ... ... Tymianski M, et al. Translational Stroke Research: Vision and Opportunities. Stroke. PMID 28751554 DOI: 10.1161/Strokeaha.117.017112  0.395
2017 Tymianski M. Combining Neuroprotection With Endovascular Treatment of Acute Stroke: Is There Hope? Stroke. PMID 28487331 DOI: 10.1161/Strokeaha.117.017040  0.333
2017 Tymianski M. Animal Models: Nonhuman Primates Primer On Cerebrovascular Diseases. 320-323. DOI: 10.1016/B978-0-12-803058-5.00067-9  0.359
2015 Xu B, Xiao AJ, Chen W, Turlova E, Liu R, Barszczyk A, Sun CL, Liu L, Tymianski M, Feng ZP, Sun HS. Neuroprotective Effects of a PSD-95 Inhibitor in Neonatal Hypoxic-Ischemic Brain Injury. Molecular Neurobiology. PMID 26520452 DOI: 10.1007/S12035-015-9488-4  0.459
2015 Shabanzadeh AP, Tassew NG, Szydlowska K, Tymianski M, Banerjee P, Vigouroux RJ, Eubanks JH, Huang L, Geraerts M, Koeberle PD, Mueller BK, Monnier PP. Uncoupling Neogenin association with lipid rafts promotes neuronal survival and functional recovery after stroke. Cell Death & Disease. 6: e1744. PMID 25950474 DOI: 10.1038/Cddis.2015.109  0.472
2015 da Costa L, Fisher J, Mikulis DJ, Tymianski M, Fierstra J. Early identification of brain tissue at risk for delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage. Acta Neurochirurgica. Supplement. 120: 105-9. PMID 25366608 DOI: 10.1007/978-3-319-04981-6_18  0.31
2014 Tymianski M. Stroke in 2013: Disappointments and advances in acute stroke intervention Nature Reviews Neurology. 10: 66-68. PMID 24394291 DOI: 10.1038/Nrneurol.2013.271  0.352
2014 Goyal M, Tymianski M. Bottlenecks in acute stroke care and research : Solutions and innovations Stroke. 45: 6-7. DOI: 10.1161/Strokeaha.113.003965  0.311
2013 Alim I, Teves L, Li R, Mori Y, Tymianski M. Modulation of NMDAR subunit expression by TRPM2 channels regulates neuronal vulnerability to ischemic cell death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 17264-77. PMID 24174660 DOI: 10.1523/Jneurosci.1729-13.2013  0.797
2013 Tymianski M. Novel approaches to neuroprotection trials in acute ischemic stroke Stroke. 44: 2942-2950. PMID 24021680 DOI: 10.1161/Strokeaha.113.000731  0.457
2013 Lanzino G, Burrows AM, Tymianski M. Advances in stroke: Vascular neurosurgery Stroke. 44: 316-317. PMID 23321447 DOI: 10.1161/Strokeaha.111.000385  0.336
2012 Hill MD, Martin RH, Mikulis D, Wong JH, Silver FL, Terbrugge KG, Milot G, Clark WM, Macdonald RL, Kelly ME, Boulton M, Fleetwood I, McDougall C, Gunnarsson T, Chow M, ... ... Tymianski M, et al. Safety and efficacy of NA-1 in patients with iatrogenic stroke after endovascular aneurysm repair (ENACT): a phase 2, randomised, double-blind, placebo-controlled trial. The Lancet. Neurology. 11: 942-50. PMID 23051991 DOI: 10.1016/S1474-4422(12)70225-9  0.331
2012 Cook DJ, Teves L, Tymianski M. A translational paradigm for the preclinical evaluation of the stroke neuroprotectant Tat-NR2B9c in gyrencephalic nonhuman primates Science Translational Medicine. 4. PMID 23035045 DOI: 10.1126/Scitranslmed.3003824  0.366
2012 Cook DJ, Tymianski M. Nonhuman Primate Models of Stroke for Translational Neuroprotection Research Neurotherapeutics. 9: 371-379. PMID 22437447 DOI: 10.1007/S13311-012-0115-Z  0.364
2012 Cook DJ, Teves L, Tymianski M. Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain Nature. 483: 213-217. PMID 22388811 DOI: 10.1038/Nature10841  0.401
2011 Xie YF, Belrose JC, Lei G, Tymianski M, Mori Y, Macdonald JF, Jackson MF. Dependence of NMDA/GSK-3β mediated metaplasticity on TRPM2 channels at hippocampal CA3-CA1 synapses. Molecular Brain. 4: 44. PMID 22188973 DOI: 10.1186/1756-6606-4-44  0.406
2011 Tymianski M. Emerging mechanisms of disrupted cellular signaling in brain ischemia Nature Neuroscience. 14: 1369-1373. PMID 22030547 DOI: 10.1038/Nn.2951  0.386
2011 Bråtane BT, Cui H, Cook DJ, Bouley J, Tymianski M, Fisher M. Neuroprotection by freezing ischemic penumbra evolution without cerebral blood flow augmentation with a postsynaptic density-95 protein inhibitor. Stroke; a Journal of Cerebral Circulation. 42: 3265-70. PMID 21903963 DOI: 10.1161/Strokeaha.111.618801  0.348
2011 Fierstra J, Spieth S, Tran L, Conklin J, Tymianski M, ter Brugge KG, Fisher JA, Mikulis DJ, Krings T. Severely impaired cerebrovascular reserve in patients with cerebral proliferative angiopathy. Journal of Neurosurgery. Pediatrics. 8: 310-5. PMID 21882924 DOI: 10.3171/2011.6.Peds1170  0.339
2011 Monnier PP, D'Onofrio PM, Magharious M, Hollander AC, Tassew N, Szydlowska K, Tymianski M, Koeberle PD. Involvement of caspase-6 and caspase-8 in neuronal apoptosis and the regenerative failure of injured retinal ganglion cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 10494-505. PMID 21775595 DOI: 10.1523/Jneurosci.0148-11.2011  0.337
2011 Cook DJ, Tymianski M. Translating promising preclinical neuroprotective therapies to human stroke trials Expert Review of Cardiovascular Therapy. 9: 433-449. PMID 21517728 DOI: 10.1586/Erc.11.34  0.359
2011 Lanzino G, D'Urso PI, Tymianski M. Advances in vascular neurosurgery 2010 Stroke. 42: 288-290. PMID 21233465 DOI: 10.1161/Strokeaha.110.605105  0.361
2010 Lau A, Tymianski M. Glutamate receptors, neurotoxicity and neurodegeneration Pflugers Archiv European Journal of Physiology. 460: 525-542. PMID 20229265 DOI: 10.1007/S00424-010-0809-1  0.44
2010 Szydlowska K, Tymianski M. Calcium, ischemia and excitotoxicity Cell Calcium. 47: 122-129. PMID 20167368 DOI: 10.1016/J.Ceca.2010.01.003  0.399
2009 Sun HS, Jackson MF, Martin LJ, Jansen K, Teves L, Cui H, Kiyonaka S, Mori Y, Jones M, Forder JP, Golde TE, Orser BA, Macdonald JF, Tymianski M. Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia. Nature Neuroscience. 12: 1300-7. PMID 19734892 DOI: 10.1038/Nn.2395  0.482
2009 Olah ME, Jackson MF, Li H, Perez Y, Sun HS, Kiyonaka S, Mori Y, Tymianski M, MacDonald JF. Ca2+-dependent induction of TRPM2 currents in hippocampal neurons. The Journal of Physiology. 587: 965-79. PMID 19124544 DOI: 10.1113/Jphysiol.2008.162289  0.42
2009 Forder JP, Tymianski M. Postsynaptic mechanisms of excitotoxicity: Involvement of postsynaptic density proteins, radicals, and oxidant molecules. Neuroscience. 158: 293-300. PMID 19041375 DOI: 10.1016/J.Neuroscience.2008.10.021  0.44
2009 da Costa L, Wallace MC, Ter Brugge KG, O'Kelly C, Willinsky RA, Tymianski M. The natural history and predictive features of hemorrhage from brain arteriovenous malformations. Stroke; a Journal of Cerebral Circulation. 40: 100-5. PMID 19008469 DOI: 10.1161/Strokeaha.108.524678  0.339
2008 Soriano FX, Martel MA, Papadia S, Vaslin A, Baxter P, Rickman C, Forder J, Tymianski M, Duncan R, Aarts M, Clarke P, Wyllie DJ, Hardingham GE. Specific targeting of pro-death NMDA receptor signals with differing reliance on the NR2B PDZ ligand. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10696-710. PMID 18923045 DOI: 10.1523/Jneurosci.1207-08.2008  0.769
2008 Sun HS, Doucette TA, Liu Y, Fang Y, Teves L, Aarts M, Ryan CL, Bernard PB, Lau A, Forder JP, Salter MW, Wang YT, Tasker RA, Tymianski M. Effectiveness of PSD95 inhibitors in permanent and transient focal ischemia in the rat. Stroke; a Journal of Cerebral Circulation. 39: 2544-53. PMID 18617669 DOI: 10.1161/Strokeaha.107.506048  0.716
2008 Besancon E, Guo S, Lok J, Tymianski M, Lo EH. Beyond NMDA and AMPA glutamate receptors: emerging mechanisms for ionic imbalance and cell death in stroke Trends in Pharmacological Sciences. 29: 268-275. PMID 18384889 DOI: 10.1016/J.Tips.2008.02.003  0.465
2007 Lau AC, Cui H, Tymianski M. The use of propidium iodide to assess excitotoxic neuronal death in primary mixed cortical cultures. Methods in Molecular Biology (Clifton, N.J.). 399: 15-29. PMID 18309922 DOI: 10.1007/978-1-59745-504-6_2  0.441
2007 Wei WL, Sun HS, Olah ME, Sun X, Czerwinska E, Czerwinski W, Mori Y, Orser BA, Xiong ZG, Jackson MF, Tymianski M, MacDonald JF. TRPM7 channels in hippocampal neurons detect levels of extracellular divalent cations. Proceedings of the National Academy of Sciences of the United States of America. 104: 16323-8. PMID 17913893 DOI: 10.1073/Pnas.0701149104  0.445
2007 Cui H, Hayashi A, Sun HS, Belmares MP, Cobey C, Phan T, Schweizer J, Salter MW, Wang YT, Tasker RA, Garman D, Rabinowitz J, Lu PS, Tymianski M. PDZ protein interactions underlying NMDA receptor-mediated excitotoxicity and neuroprotection by PSD-95 inhibitors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9901-15. PMID 17855605 DOI: 10.1523/Jneurosci.1464-07.2007  0.422
2007 Liu Y, Wong TP, Aarts M, Rooyakkers A, Liu L, Lai TW, Wu DC, Lu J, Tymianski M, Craig AM, Wang YT. NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2846-57. PMID 17360906 DOI: 10.1523/Jneurosci.0116-07.2007  0.786
2006 Da Costa LB, Tymianski M. Symptomatic non-atherosclerotic bilateral extracranial vertebral artery occlusion treated with extracranial to intracranial bypass: Case report Arquivos De Neuro-Psiquiatria. 64. PMID 17119815 DOI: 10.1590/S0004-282X2006000400028  0.322
2006 Lau A, Arundine M, Sun HS, Jones M, Tymianski M. Inhibition of caspase-mediated apoptosis by peroxynitrite in traumatic brain injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11540-53. PMID 17093075 DOI: 10.1523/Jneurosci.3507-06.2006  0.791
2005 Aarts MM, Tymianski M. TRPMs and neuronal cell death. Pflã¼Gers Archiv : European Journal of Physiology. 451: 243-9. PMID 16044308 DOI: 10.1007/S00424-005-1439-X  0.766
2005 Aarts MM, Tymianski M. TRPM7 and ischemic CNS injury. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 11: 116-23. PMID 15746380 DOI: 10.1177/1073858404272966  0.762
2005 Liu Y, Wong TP, Aarts M, Liu L, Wu D, Lu J, Tymianski M, Wang Y. Subunit-specific effects of NMDA receptor signaling: Implications for stroke Journal of Cerebral Blood Flow & Metabolism. 25: S431-S431. DOI: 10.1038/Sj.Jcbfm.9591524.0431  0.786
2004 Arundine M, Aarts M, Lau A, Tymianski M. Vulnerability of central neurons to secondary insults after in vitro mechanical stretch. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8106-23. PMID 15371512 DOI: 10.1523/Jneurosci.1362-04.2004  0.793
2004 Arundine M, Tymianski M. Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury. Cellular and Molecular Life Sciences : Cmls. 61: 657-68. PMID 15052409 DOI: 10.1007/S00018-003-3319-X  0.822
2004 Aarts MM, Tymianski M. Molecular mechanisms underlying specificity of excitotoxic signaling in neurons. Current Molecular Medicine. 4: 137-47. PMID 15032710 DOI: 10.2174/1566524043479202  0.755
2003 Aarts MM, Arundine M, Tymianski M. Novel concepts in excitotoxic neurodegeneration after stroke. Expert Reviews in Molecular Medicine. 5: 1-22. PMID 14987406 DOI: 10.1017/S1462399403007087  0.801
2003 Arundine M, Chopra GK, Wrong A, Lei S, Aarts MM, MacDonald JF, Tymianski M. Enhanced vulnerability to NMDA toxicity in sublethal traumatic neuronal injury in vitro. Journal of Neurotrauma. 20: 1377-95. PMID 14748985 DOI: 10.1089/089771503322686166  0.798
2003 Aarts M, Iihara K, Wei WL, Xiong ZG, Arundine M, Cerwinski W, MacDonald JF, Tymianski M. A key role for TRPM7 channels in anoxic neuronal death. Cell. 115: 863-77. PMID 14697204 DOI: 10.1016/S0092-8674(03)01017-1  0.787
2003 Aarts MM, Tymianski M. Peptide action in stroke therapy. Expert Opinion On Biological Therapy. 3: 1093-104. PMID 14519074 DOI: 10.1517/14712598.3.7.1093  0.771
2003 Aarts MM, Tymianski M. Novel treatment of excitotoxicity: targeted disruption of intracellular signalling from glutamate receptors. Biochemical Pharmacology. 66: 877-86. PMID 12963474 DOI: 10.1016/S0006-2952(03)00297-1  0.746
2003 Arundine M, Tymianski M. Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity. Cell Calcium. 34: 325-37. PMID 12909079 DOI: 10.1016/S0143-4160(03)00141-6  0.786
2003 Aarts MM, Arundine M, Tymianski M. Novel concepts in excitotoxic neurodegeneration after stroke Expert Reviews in Molecular Medicine. 5. DOI: 10.1017/S1462399403007087  0.765
2002 Aarts M, Liu Y, Liu L, Besshoh S, Arundine M, Gurd JW, Wang YT, Salter MW, Tymianski M. Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions. Science (New York, N.Y.). 298: 846-50. PMID 12399596 DOI: 10.1126/Science.1072873  0.807
2001 Sattler R, Tymianski M. Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell death. Molecular Neurobiology. 24: 107-29. PMID 11831548 DOI: 10.1385/Mn:24:1-3:107  0.492
2001 Iihara K, Joo DT, Henderson J, Sattler R, Taverna FA, Lourensen S, Orser BA, Roder JC, Tymianski M. The influence of glutamate receptor 2 expression on excitotoxicity in Glur2 null mutant mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 2224-39. PMID 11264298 DOI: 10.1523/Jneurosci.21-07-02224.2001  0.462
2000 Sattler R, Tymianski M. Molecular mechanisms of calcium-dependent excitotoxicity. Journal of Molecular Medicine (Berlin, Germany). 78: 3-13. PMID 10759025 DOI: 10.1007/S001090000077  0.434
2000 Sattler R, Xiong Z, Lu WY, MacDonald JF, Tymianski M. Distinct roles of synaptic and extrasynaptic NMDA receptors in excitotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 22-33. PMID 10627577 DOI: 10.1523/Jneurosci.20-01-00022.2000  0.415
1999 Sattler R, Xiong Z, Lu WY, Hafner M, MacDonald JF, Tymianski M. Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein. Science (New York, N.Y.). 284: 1845-8. PMID 10364559 DOI: 10.1126/Science.284.5421.1845  0.45
1998 Sattler R, Charlton MP, Hafner M, Tymianski M. Distinct influx pathways, not calcium load, determine neuronal vulnerability to calcium neurotoxicity. Journal of Neurochemistry. 71: 2349-64. PMID 9832133 DOI: 10.1046/J.1471-4159.1998.71062349.X  0.342
1998 Tymianski M, Sattler R, Zabramski JM, Spetzler RF. Characterization of neuroprotection from excitotoxicity by moderate and profound hypothermia in cultured cortical neurons unmasks a temperature-insensitive component of glutamate neurotoxicity. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 18: 848-67. PMID 9701346 DOI: 10.1097/00004647-199808000-00005  0.443
1997 Sattler R, Charlton MP, Hafner M, Tymianski M. Determination of the time course and extent of neurotoxicity at defined temperatures in cultured neurons using a modified multiwell plate fluorescence scanner. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 17: 455-63. PMID 9143228 DOI: 10.1097/00004647-199704000-00011  0.38
1997 Abdel-Hamid KM, Tymianski M. Mechanisms and effects of intracellular calcium buffering on neuronal survival in organotypic hippocampal cultures exposed to anoxia/aglycemia or to excitotoxins Journal of Neuroscience. 17: 3538-3553. PMID 9133378 DOI: 10.1523/Jneurosci.17-10-03538.1997  0.431
1997 Tymianski M, Bernstein GM, Abdel-Hamid KM, Sattler R, Velumian A, Carlen PL, Razavi H, Jones OT. A novel use for a carbodiimide compound for the fixation of fluorescent and non-fluorescent calcium indicators in situ following physiological experiments. Cell Calcium. 21: 175-83. PMID 9105727 DOI: 10.1016/S0143-4160(97)90042-7  0.307
1997 Tymianski M, Sattler RG. Is Calcium Involved in Excitotoxic or Ischemic Neuronal Damage Primer On Cerebrovascular Diseases. 190-192. DOI: 10.1016/B978-012743170-3.50053-4  0.442
1996 Spigelman I, Tymianski M, Wallace CM, Carlen PL, Velumian AA. Modulation of hippocampal synaptic transmission by low concentrations of cell-permeant Ca2+ chelators: effects of Ca2+ affinity, chelator structure and binding kinetics. Neuroscience. 75: 559-72. PMID 8931019 DOI: 10.1016/0306-4522(96)00283-7  0.31
1996 Ouanounou A, Zhang L, Tymianski M, Charlton MP, Wallace MC, Carlen PL. Accumulation and extrusion of permeant Ca2+ chelators in attenuation of synaptic transmission at hippocampal CA1 neurons. Neuroscience. 75: 99-109. PMID 8923526 DOI: 10.1016/0306-4522(96)00319-3  0.325
1996 Sattler R, Tymianski M, Feyaz I, Hafner M, Tator CH. Voltage-sensitive calcium channels mediate calcium entry into cultured mammalian sympathetic neurons following neurite transection. Brain Research. 719: 239-46. PMID 8782889 DOI: 10.1016/0006-8993(96)00125-4  0.362
1996 Tymianski M, Tator CH. Normal and abnormal calcium homeostasis in neurons: A basis for the pathophysiology of traumatic and ischemic central nervous system injury Neurosurgery. 38: 1176-1195. PMID 8727150 DOI: 10.1097/00006123-199606000-00028  0.385
1995 Zhang L, Pennefather P, Velumian A, Tymianski M, Charlton M, Carlen PL. Potentiation of a slow Ca(2+)-dependent K+ current by intracellular Ca2+ chelators in hippocampal CA1 neurons of rat brain slices. Journal of Neurophysiology. 74: 2225-41. PMID 8747186 DOI: 10.1152/Jn.1995.74.6.2225  0.345
1995 Tymianski M. Neuroprotection in vitro and in vivo by cell membrane-permeant Ca2+ chelators Clinical and Experimental Pharmacology and Physiology. 22: 299-300. PMID 7671447 DOI: 10.1111/J.1440-1681.1995.Tb02002.X  0.342
1994 Tymianski M, Spigelman I, Zhang L, Carlen PL, Tator CH, Charlton MP, Wallace MC. Mechanism of action and persistence of neuroprotection by cell-permeant Ca2+ chelators. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 14: 911-23. PMID 7929656 DOI: 10.1038/Jcbfm.1994.122  0.383
1994 Tymianski M, Wang LY, MacDonald JF. Alteration of neuronal calcium homeostasis and excitotoxic vulnerability by chronic depolarization. Brain Research. 648: 291-5. PMID 7922543 DOI: 10.1016/0006-8993(94)91129-0  0.4
1994 Tymianski M, Charlton MP, Carlen PL, Tator CH. Properties of neuroprotective cell-permeant Ca2+ chelators: effects on [Ca2+]i and glutamate neurotoxicity in vitro. Journal of Neurophysiology. 72: 1973-92. PMID 7823112 DOI: 10.1152/Jn.1994.72.4.1973  0.386
1993 Tymianski M, Wallace MC, Spigelman I, Uno M, Carlen PL, Tator CH, Charlton MP. Cell-permeant Ca2+ chelators reduce early excitotoxic and ischemic neuronal injury in vitro and in vivo. Neuron. 11: 221-35. PMID 8102532 DOI: 10.1016/0896-6273(93)90180-Y  0.442
1993 Tymianski M, Charlton MP, Carlen PL, Tator CH. Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 2085-104. PMID 8097530 DOI: 10.1523/Jneurosci.13-05-02085.1993  0.379
1993 Tymianski M, Charlton MP, Carlen PL, Tator CH. Secondary Ca2+ overload indicates early neuronal injury which precedes staining with viability indicators. Brain Research. 607: 319-23. PMID 7683241 DOI: 10.1016/0006-8993(93)91523-U  0.36
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