Trudy Kohout - Publications

Affiliations: 
Duke University, Durham, NC 

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2007 Kohout TA, Xie Q, Reijmers S, Finn KJ, Guo Z, Zhu YF, Struthers RS. Trapping of a nonpeptide ligand by the extracellular domains of the gonadotropin-releasing hormone receptor results in insurmountable antagonism. Molecular Pharmacology. 72: 238-47. PMID 17409285 DOI: 10.1124/mol.107.035535  0.34
2005 Gesty-Palmer D, El Shewy H, Kohout TA, Luttrell LM. beta-Arrestin 2 expression determines the transcriptional response to lysophosphatidic acid stimulation in murine embryo fibroblasts. The Journal of Biological Chemistry. 280: 32157-67. PMID 16027114 DOI: 10.1074/jbc.M507460200  0.809
2005 Perry SJ, Junger S, Kohout TA, Hoare SRJ, Struthers RS, Grigoriadis DE, Maki RA. Distinct conformations of the corticotropin releasing factor type 1 receptor adopted following agonist and antagonist binding are differentially regulated Journal of Biological Chemistry. 280: 11560-11568. PMID 15653688 DOI: 10.1074/jbc.M412914200  0.397
2005 Naik S, Billington CK, Pascual RM, Deshpande DA, Stefano FP, Kohout TA, Eckman DM, Benovic JL, Penn RB. Regulation of cysteinyl leukotriene type 1 receptor internalization and signaling. The Journal of Biological Chemistry. 280: 8722-32. PMID 15590629 DOI: 10.1074/Jbc.M413014200  0.576
2004 Kohout TA, Nicholas SL, Perry SJ, Reinhart G, Junger S, Struthers RS. Differential desensitization, receptor phosphorylation, β-arrestin recruitment, and ERK1/2 activation by the two endogenous ligands for the CC chemokine receptor 7 Journal of Biological Chemistry. 279: 23214-23222. PMID 15054093 DOI: 10.1074/jbc.M402125200  0.397
2003 Povsic TJ, Kohout TA, Lefkowitz RJ. Beta-arrestin1 mediates insulin-like growth factor 1 (IGF-1) activation of phosphatidylinositol 3-kinase (PI3K) and anti-apoptosis. The Journal of Biological Chemistry. 278: 51334-9. PMID 14534298 DOI: 10.1074/jbc.M309968200  0.746
2003 Azzi M, Charest PG, Angers S, Rousseau G, Kohout T, Bouvier M, Piñeyro G. Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors. Proceedings of the National Academy of Sciences of the United States of America. 100: 11406-11. PMID 13679574 DOI: 10.1073/Pnas.1936664100  0.773
2003 Vines CM, Revankar CM, Maestas DC, LaRusch LL, Cimino DF, Kohout TA, Lefkowitz RJ, Prossnitz ER. N-formyl peptide receptors internalize but do not recycle in the absence of arrestins. The Journal of Biological Chemistry. 278: 41581-4. PMID 12947104 DOI: 10.1074/Jbc.C300291200  0.525
2003 Wu JH, Peppel K, Nelson CD, Lin FT, Kohout TA, Miller WE, Exum ST, Freedman NJ. The adaptor protein beta-arrestin2 enhances endocytosis of the low density lipoprotein receptor. The Journal of Biological Chemistry. 278: 44238-45. PMID 12944399 DOI: 10.1074/Jbc.M309450200  0.6
2003 Fraile-Ramos A, Kohout TA, Waldhoer M, Marsh M. Endocytosis of the viral chemokine receptor US28 does not require beta-arrestins but is dependent on the clathrin-mediated pathway. Traffic (Copenhagen, Denmark). 4: 243-53. PMID 12694563  0.709
2003 Joensen L, Borda E, Kohout T, Perry S, García G, Sterin-Borda L. Trypanosoma cruzi antigen that interacts with the beta1-adrenergic receptor and modifies myocardial contractile activity. Molecular and Biochemical Parasitology. 127: 169-77. PMID 12672526 DOI: 10.1016/S0166-6851(03)00003-3  0.619
2003 Kohout TA, Lefkowitz RJ. Regulation of G protein-coupled receptor kinases and arrestins during receptor desensitization. Molecular Pharmacology. 63: 9-18. PMID 12488531 DOI: 10.1124/mol.63.1.9  0.509
2002 Perry SJ, Baillie GS, Kohout TA, McPhee I, Magiera MM, Ang KL, Miller WE, McLean AJ, Conti M, Houslay MD, Lefkowitz RJ. Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins. Science (New York, N.Y.). 298: 834-6. PMID 12399592 DOI: 10.1126/Science.1074683  0.793
2002 Hanyaloglu AC, Seeber RM, Kohout TA, Lefkowitz RJ, Eidne KA. Homo- and hetero-oligomerization of thyrotropin-releasing hormone (TRH) receptor subtypes. Differential regulation of beta-arrestins 1 and 2. The Journal of Biological Chemistry. 277: 50422-30. PMID 12393857 DOI: 10.1074/jbc.M209340200  0.767
2002 Paing MM, Stutts AB, Kohout TA, Lefkowitz RJ, Trejo J. beta -Arrestins regulate protease-activated receptor-1 desensitization but not internalization or Down-regulation. The Journal of Biological Chemistry. 277: 1292-300. PMID 11694535 DOI: 10.1074/Jbc.M109160200  0.795
2001 Kohout TA, Takaoka H, McDonald PH, Perry SJ, Mao L, Lefkowitz RJ, Rockman HA. Augmentation of cardiac contractility mediated by the human beta(3)-adrenergic receptor overexpressed in the hearts of transgenic mice. Circulation. 104: 2485-91. PMID 11705829 DOI: 10.1161/Hc4501.098933  0.672
2001 Shenoy SK, McDonald PH, Kohout TA, Lefkowitz RJ. Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin. Science (New York, N.Y.). 294: 1307-13. PMID 11588219 DOI: 10.1126/Science.1063866  0.777
2001 Kohout TA, Lin FS, Perry SJ, Conner DA, Lefkowitz RJ. beta-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking. Proceedings of the National Academy of Sciences of the United States of America. 98: 1601-6. PMID 11171997 DOI: 10.1073/pnas.041608198  0.776
2000 Wei SK, Colecraft HM, DeMaria CD, Peterson BZ, Zhang R, Kohout TA, Rogers TB, Yue DT. Ca(2+) channel modulation by recombinant auxiliary beta subunits expressed in young adult heart cells. Circulation Research. 86: 175-84. PMID 10666413 DOI: 10.1161/01.Res.86.2.175  0.545
1991 Sidhu A, Sullivan M, Kohout T, Balen P, Fishman PH. D1 dopamine receptors can interact with both stimulatory and inhibitory guanine nucleotide binding proteins. Journal of Neurochemistry. 57: 1445-1451. PMID 1832710 DOI: 10.1111/J.1471-4159.1991.Tb08312.X  0.314
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