Year |
Citation |
Score |
2013 |
Robinson JD, Pitcher JA. G protein-coupled receptor kinase 2 (GRK2) is a Rho-activated scaffold protein for the ERK MAP kinase cascade. Cellular Signalling. 25: 2831-9. PMID 24018045 DOI: 10.1016/j.cellsig.2013.08.031 |
0.608 |
|
2013 |
Johnson LR, Robinson JD, Lester KN, Pitcher JA. Distinct structural features of G protein-coupled receptor kinase 5 (GRK5) regulate its nuclear localization and DNA-binding ability. Plos One. 8: e62508. PMID 23658733 DOI: 10.1371/journal.pone.0062508 |
0.452 |
|
2008 |
Martini JS, Raake P, Vinge LE, DeGeorge BR, DeGeorge B, Chuprun JK, Harris DM, Gao E, Eckhart AD, Pitcher JA, Koch WJ. Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes. Proceedings of the National Academy of Sciences of the United States of America. 105: 12457-62. PMID 18711143 DOI: 10.1073/pnas.0803153105 |
0.566 |
|
2008 |
Martini JS, Raake P, Vinge LE, DeGeorge BR, Chuprun JK, Harris DM, Gao E, Eckhart AD, Pitcher JA, Koch WJ. Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes (Proceedings of the National Academy of Sciences of the United States of America (2008) 105, (12457-12462) DOI: 10.1073/pnas.0803153105) Proceedings of the National Academy of Sciences of the United States of America. 105: 17206. DOI: 10.1073/pnas.0808974105 |
0.636 |
|
2007 |
Cotton M, Boulay PL, Houndolo T, Vitale N, Pitcher JA, Claing A. Endogenous ARF6 interacts with Rac1 upon angiotensin II stimulation to regulate membrane ruffling and cell migration. Molecular Biology of the Cell. 18: 501-11. PMID 17122362 DOI: 10.1091/Mbc.E06-06-0567 |
0.677 |
|
2007 |
Martini JS, Raake P, Vinge LE, DeGeorge BR, Chuprun JK, Harris DM, Eckhart AE, Pitcher JA, Koch WJ. A Novel Nuclear Function for GRK5 and Its Potential Role in the Hypertrophic Response Journal of Cardiac Failure. 13: S71. DOI: 10.1016/j.cardfail.2007.06.311 |
0.355 |
|
2006 |
Scott MG, Pierotti V, Storez H, Lindberg E, Thuret A, Muntaner O, Labbé-Jullié C, Pitcher JA, Marullo S. Cooperative regulation of extracellular signal-regulated kinase activation and cell shape change by filamin A and beta-arrestins. Molecular and Cellular Biology. 26: 3432-45. PMID 16611986 DOI: 10.1128/MCB.26.9.3432-3445.2006 |
0.551 |
|
2005 |
Cant SH, Pitcher JA. G protein-coupled receptor kinase 2-mediated phosphorylation of ezrin is required for G protein-coupled receptor-dependent reorganization of the actin cytoskeleton. Molecular Biology of the Cell. 16: 3088-99. PMID 15843435 DOI: 10.1091/mbc.e04-10-0877 |
0.669 |
|
2004 |
Johnson LR, Scott MG, Pitcher JA. G protein-coupled receptor kinase 5 contains a DNA-binding nuclear localization sequence. Molecular and Cellular Biology. 24: 10169-79. PMID 15542828 DOI: 10.1128/MCB.24.23.10169-10179.2004 |
0.505 |
|
2004 |
Fairfax BP, Pitcher JA, Scott MG, Calver AR, Pangalos MN, Moss SJ, Couve A. Phosphorylation and chronic agonist treatment atypically modulate GABAB receptor cell surface stability. The Journal of Biological Chemistry. 279: 12565-73. PMID 14707142 DOI: 10.1074/jbc.M311389200 |
0.402 |
|
2003 |
Lodowski DT, Barnhill JF, Pitcher JA, Capel WD, Lefkowitz RJ, Tesmer JJ. Purification, crystallization and preliminary X-ray diffraction studies of a complex between G protein-coupled receptor kinase 2 and Gbeta1gamma2. Acta Crystallographica. Section D, Biological Crystallography. 59: 936-9. PMID 12777817 DOI: 10.1107/S0907444903002622 |
0.652 |
|
2003 |
Lodowski DT, Pitcher JA, Capel WD, Lefkowitz RJ, Tesmer JJ. Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gbetagamma. Science (New York, N.Y.). 300: 1256-62. PMID 12764189 DOI: 10.1126/Science.1082348 |
0.697 |
|
2002 |
Freeman JL, Gonzalo P, Pitcher JA, Claing A, Lavergne JP, Reboud JP, Lefkowitz RJ. Beta 2-adrenergic receptor stimulated, G protein-coupled receptor kinase 2 mediated, phosphorylation of ribosomal protein P2. Biochemistry. 41: 12850-7. PMID 12379128 DOI: 10.1021/Bi020145D |
0.808 |
|
2001 |
Cong M, Perry SJ, Lin FT, Fraser ID, Hu LA, Chen W, Pitcher JA, Scott JD, Lefkowitz RJ. Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by protein kinase A and its anchoring protein AKAP79. The Journal of Biological Chemistry. 276: 15192-9. PMID 11278469 DOI: 10.1074/jbc.M009130200 |
0.846 |
|
2000 |
Freeman JL, Pitcher JA, Li X, Bennett V, Lefkowitz RJ. alpha-Actinin is a potent regulator of G protein-coupled receptor kinase activity and substrate specificity in vitro. Febs Letters. 473: 280-4. PMID 10818226 DOI: 10.1016/S0014-5793(00)01543-X |
0.613 |
|
1999 |
Pitcher JA, Tesmer JJ, Freeman JL, Capel WD, Stone WC, Lefkowitz RJ. Feedback inhibition of G protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases. The Journal of Biological Chemistry. 274: 34531-4. PMID 10574913 DOI: 10.1074/Jbc.274.49.34531 |
0.75 |
|
1999 |
Tang Y, Hu LA, Miller WE, Ringstad N, Hall RA, Pitcher JA, DeCamilli P, Lefkowitz RJ. Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the beta1-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 96: 12559-64. PMID 10535961 DOI: 10.1073/Pnas.96.22.12559 |
0.824 |
|
1999 |
Hall RA, Spurney RF, Premont RT, Rahman N, Blitzer JT, Pitcher JA, Lefkowitz RJ. G protein-coupled receptor kinase 6A phosphorylates the Na(+)/H(+) exchanger regulatory factor via a PDZ domain-mediated interaction. The Journal of Biological Chemistry. 274: 24328-34. PMID 10446210 DOI: 10.1074/Jbc.274.34.24328 |
0.781 |
|
1999 |
McDonald PH, Cote NL, Lin FT, Premont RT, Pitcher JA, Lefkowitz RJ. Identification of NSF as a beta-arrestin1-binding protein. Implications for beta2-adrenergic receptor regulation. The Journal of Biological Chemistry. 274: 10677-80. PMID 10196135 DOI: 10.1074/Jbc.274.16.10677 |
0.82 |
|
1998 |
Premont RT, Claing A, Vitale N, Freeman JL, Pitcher JA, Patton WA, Moss J, Vaughan M, Lefkowitz RJ. beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein. Proceedings of the National Academy of Sciences of the United States of America. 95: 14082-7. PMID 9826657 DOI: 10.1073/Pnas.95.24.14082 |
0.865 |
|
1998 |
Pitcher JA, Freedman NJ, Lefkowitz RJ. G protein-coupled receptor kinases. Annual Review of Biochemistry. 67: 653-92. PMID 9759500 DOI: 10.1146/annurev.biochem.67.1.653 |
0.842 |
|
1998 |
Freeman JL, De La Cruz EM, Pollard TD, Lefkowitz RJ, Pitcher JA. Regulation of G protein-coupled receptor kinase 5 (GRK5) by actin. The Journal of Biological Chemistry. 273: 20653-7. PMID 9685424 DOI: 10.1074/Jbc.273.32.20653 |
0.671 |
|
1998 |
Pitcher JA, Hall RA, Daaka Y, Zhang J, Ferguson SS, Hester S, Miller S, Caron MG, Lefkowitz RJ, Barak LS. The G protein-coupled receptor kinase 2 is a microtubule-associated protein kinase that phosphorylates tubulin. The Journal of Biological Chemistry. 273: 12316-24. PMID 9575184 DOI: 10.1074/Jbc.273.20.12316 |
0.851 |
|
1998 |
Hall RA, Premont RT, Chow CW, Blitzer JT, Pitcher JA, Claing A, Stoffel RH, Barak LS, Shenolikar S, Weinman EJ, Grinstein S, Lefkowitz RJ. The beta2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange. Nature. 392: 626-30. PMID 9560162 DOI: 10.1038/33458 |
0.792 |
|
1998 |
Lefkowitz RJ, Pitcher J, Krueger K, Daaka Y. Mechanisms of beta-adrenergic receptor desensitization and resensitization. Advances in Pharmacology (San Diego, Calif.). 42: 416-20. PMID 9327928 DOI: 10.1016/S1054-3589(08)60777-2 |
0.854 |
|
1997 |
Lin FT, Krueger KM, Kendall HE, Daaka Y, Fredericks ZL, Pitcher JA, Lefkowitz RJ. Clathrin-mediated endocytosis of the beta-adrenergic receptor is regulated by phosphorylation/dephosphorylation of beta-arrestin1. The Journal of Biological Chemistry. 272: 31051-7. PMID 9388255 DOI: 10.1074/Jbc.272.49.31051 |
0.827 |
|
1997 |
Stoffel RH, Pitcher JA, Lefkowitz RJ. Targeting G protein-coupled receptor kinases to their receptor substrates. The Journal of Membrane Biology. 157: 1-8. PMID 9141353 DOI: 10.1007/S002329900210 |
0.643 |
|
1997 |
Daaka Y, Pitcher JA, Richardson M, Stoffel RH, Robishaw JD, Lefkowitz RJ. Receptor and G betagamma isoform-specific interactions with G protein-coupled receptor kinases. Proceedings of the National Academy of Sciences of the United States of America. 94: 2180-5. PMID 9122168 DOI: 10.1073/Pnas.94.6.2180 |
0.808 |
|
1997 |
Krueger KM, Daaka Y, Pitcher JA, Lefkowitz RJ. The role of sequestration in G protein-coupled receptor resensitization. Regulation of beta2-adrenergic receptor dephosphorylation by vesicular acidification. The Journal of Biological Chemistry. 272: 5-8. PMID 8995214 DOI: 10.1074/Jbc.272.1.5 |
0.811 |
|
1997 |
Lefkowitz RJ, Pitcher J, Krueger K, Daaka Y. Mechanisms of β-Adrenergic Receptor Desensitization and Resensitization Advances in Pharmacology. 42: 416-420. DOI: 10.1016/S1054-3589(08)60777-2 |
0.753 |
|
1996 |
Pitcher JA, Fredericks ZL, Stone WC, Premont RT, Stoffel RH, Koch WJ, Lefkowitz RJ. Phosphatidylinositol 4,5-bisphosphate (PIP2)-enhanced G protein-coupled receptor kinase (GRK) activity. Location, structure, and regulation of the PIP2 binding site distinguishes the GRK subfamilies. The Journal of Biological Chemistry. 271: 24907-13. PMID 8798768 DOI: 10.1074/Jbc.271.40.24907 |
0.841 |
|
1996 |
Fredericks ZL, Pitcher JA, Lefkowitz RJ. Identification of the G protein-coupled receptor kinase phosphorylation sites in the human beta2-adrenergic receptor. The Journal of Biological Chemistry. 271: 13796-803. PMID 8662852 DOI: 10.1074/Jbc.271.23.13796 |
0.694 |
|
1996 |
Premont RT, Macrae AD, Stoffel RH, Chung N, Pitcher JA, Ambrose C, Inglese J, MacDonald ME, Lefkowitz RJ. Characterization of the G protein-coupled receptor kinase GRK4. Identification of four splice variants. The Journal of Biological Chemistry. 271: 6403-10. PMID 8626439 DOI: 10.1074/Jbc.271.11.6403 |
0.731 |
|
1995 |
Pitcher JA, Touhara K, Payne ES, Lefkowitz RJ. Pleckstrin homology domain-mediated membrane association and activation of the beta-adrenergic receptor kinase requires coordinate interaction with G beta gamma subunits and lipid. The Journal of Biological Chemistry. 270: 11707-10. PMID 7744811 DOI: 10.1074/JBC.270.20.11707 |
0.747 |
|
1995 |
Pitcher JA, Payne ES, Csortos C, DePaoli-Roach AA, Lefkowitz RJ. The G-protein-coupled receptor phosphatase: a protein phosphatase type 2A with a distinct subcellular distribution and substrate specificity. Proceedings of the National Academy of Sciences of the United States of America. 92: 8343-7. PMID 7667292 DOI: 10.1073/Pnas.92.18.8343 |
0.63 |
|
1993 |
Lefkowitz RJ, Inglese J, Koch WJ, Pitcher J, Attramadal H, Caron MG. G-protein-coupled receptors: regulatory role of receptor kinases and arrestin proteins. Cold Spring Harbor Symposia On Quantitative Biology. 57: 127-33. PMID 1339651 DOI: 10.1101/Sqb.1992.057.01.016 |
0.845 |
|
1992 |
Hausdorff WP, Pitcher JA, Luttrell DK, Linder ME, Kurose H, Parsons SJ, Caron MG, Lefkowitz RJ. Tyrosine phosphorylation of G protein α subunits by pp60c-src Proceedings of the National Academy of Sciences of the United States of America. 89: 5720-5724. PMID 1378615 DOI: 10.1073/Pnas.89.13.5720 |
0.788 |
|
1992 |
Lohse MJ, Andexinger S, Pitcher J, Trukawinski S, Codina J, Faure JP, Caron MG, Lefkowitz RJ. Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems. The Journal of Biological Chemistry. 267: 8558-64. PMID 1349018 |
0.718 |
|
1992 |
Pitcher J, Lohse MJ, Codina J, Caron MG, Lefkowitz RJ. Desensitization of the isolated beta 2-adrenergic receptor by beta-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanisms. Biochemistry. 31: 3193-7. PMID 1348186 DOI: 10.1021/Bi00127A021 |
0.781 |
|
1992 |
Pitcher JA, Inglese J, Higgins JB, Arriza JL, Casey PJ, Kim C, Benovic JL, Kwatra MM, Caron MG, Lefkowitz RJ. Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors. Science (New York, N.Y.). 257: 1264-7. PMID 1325672 DOI: 10.1126/Science.1325672 |
0.772 |
|
1988 |
Poulter L, Ang SG, Gibson BW, Williams DH, Holmes CF, Caudwell FB, Pitcher J, Cohen P. Analysis of the in vivo phosphorylation state of rabbit skeletal muscle glycogen synthase by fast-atom-bombardment mass spectrometry. European Journal of Biochemistry. 175: 497-510. PMID 2842154 DOI: 10.1111/J.1432-1033.1988.Tb14222.X |
0.312 |
|
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