Year |
Citation |
Score |
2019 |
Wang J, Ren XR, Piao H, Zhao S, Osada T, Premont RT, Mook RA, Morse MA, Lyerly HK, Chen W. Niclosamide-induced Wnt signaling inhibition in colorectal cancer is mediated by autophagy. The Biochemical Journal. PMID 30635359 DOI: 10.1042/Bcj20180385 |
0.608 |
|
2018 |
Mook RA, Wang J, Ren XR, Piao H, Lyerly HK, Chen W. Identification of novel triazole inhibitors of Wnt/β-catenin signaling based on the Niclosamide chemotype. Bioorganic & Medicinal Chemistry Letters. PMID 30551901 DOI: 10.1016/j.bmcl.2018.11.022 |
0.322 |
|
2018 |
Wang J, Mook RA, Ren XR, Zhang Q, Jing G, Lu M, Spasojevic I, Lyerly HK, Hsu D, Chen W. Identification of DK419, a potent inhibitor of Wnt/β-catenin signaling and colorectal cancer growth. Bioorganic & Medicinal Chemistry. PMID 30274939 DOI: 10.1016/j.bmc.2018.09.016 |
0.318 |
|
2017 |
Bhattacharyya J, Ren XR, Mook RA, Wang J, Spasojevic I, Premont RT, Li X, Chilkoti A, Chen W. Niclosamide-conjugated polypeptide nanoparticles inhibit Wnt signaling and colon cancer growth. Nanoscale. PMID 28828438 DOI: 10.1039/C7Nr01973D |
0.531 |
|
2017 |
Mook RA, Ren XR, Wang J, Piao H, Barak LS, Kim Lyerly H, Chen W. Benzimidazole inhibitors from the Niclosamide chemotype inhibit Wnt/β-catenin signaling with selectivity over effects on ATP homeostasis. Bioorganic & Medicinal Chemistry. PMID 28233680 DOI: 10.1016/j.bmc.2017.01.046 |
0.34 |
|
2015 |
Mook RA, Wang J, Ren XR, Chen M, Spasojevic I, Barak LS, Lyerly HK, Chen W. Structure-activity studies of Wnt/β-catenin inhibition in the Niclosamide chemotype: Identification of derivatives with improved drug exposure. Bioorganic & Medicinal Chemistry. 23: 5829-38. PMID 26272032 DOI: 10.1016/J.Bmc.2015.07.001 |
0.504 |
|
2013 |
Lu J, Chen M, Ren XR, Wang J, Lyerly HK, Barak L, Chen W. Regulation of hedgehog signaling by Myc-interacting zinc finger protein 1, Miz1. Plos One. 8: e63353. PMID 23671675 DOI: 10.1371/Journal.Pone.0063353 |
0.564 |
|
2012 |
Ren XR, Wei J, Lei G, Wang J, Lu J, Xia W, Spector N, Barak LS, Clay TM, Osada T, Hamilton E, Blackwell K, Hobeika AC, Morse MA, Lyerly HK, et al. Polyclonal HER2-specific antibodies induced by vaccination mediate receptor internalization and degradation in tumor cells. Breast Cancer Research : Bcr. 14: R89. PMID 22676470 DOI: 10.1186/bcr3204 |
0.31 |
|
2010 |
Wang J, Lu J, Bond MC, Chen M, Ren XR, Lyerly HK, Barak LS, Chen W. Identification of select glucocorticoids as Smoothened agonists: potential utility for regenerative medicine. Proceedings of the National Academy of Sciences of the United States of America. 107: 9323-8. PMID 20439738 DOI: 10.1073/Pnas.0910712107 |
0.591 |
|
2009 |
Chen M, Wang J, Lu J, Bond MC, Ren XR, Lyerly HK, Barak LS, Chen W. The anti-helminthic niclosamide inhibits Wnt/Frizzled1 signaling. Biochemistry. 48: 10267-74. PMID 19772353 DOI: 10.1021/Bi9009677 |
0.673 |
|
2009 |
Ahn S, Kim J, Hara MR, Ren XR, Lefkowitz RJ. {beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation. The Journal of Biological Chemistry. 284: 8855-65. PMID 19171933 DOI: 10.1074/Jbc.M808463200 |
0.818 |
|
2008 |
Ren XR, Hong Y, Feng Z, Yang HM, Mei L, Xiong WC. Tyrosine phosphorylation of netrin receptors in netrin-1 signaling. Neuro-Signals. 16: 235-45. PMID 18253061 DOI: 10.1159/000111566 |
0.353 |
|
2006 |
Violin JD, Ren XR, Lefkowitz RJ. G-protein-coupled receptor kinase specificity for beta-arrestin recruitment to the beta2-adrenergic receptor revealed by fluorescence resonance energy transfer. The Journal of Biological Chemistry. 281: 20577-88. PMID 16687412 DOI: 10.1074/jbc.M513605200 |
0.797 |
|
2006 |
Xie Y, Hong Y, Ma XY, Ren XR, Ackerman S, Mei L, Xiong WC. DCC-dependent phospholipase C signaling in netrin-1-induced neurite elongation. The Journal of Biological Chemistry. 281: 2605-11. PMID 16321979 DOI: 10.1074/Jbc.M512767200 |
0.317 |
|
2005 |
Kim J, Ahn S, Ren XR, Whalen EJ, Reiter E, Wei H, Lefkowitz RJ. Functional antagonism of different G protein-coupled receptor kinases for beta-arrestin-mediated angiotensin II receptor signaling. Proceedings of the National Academy of Sciences of the United States of America. 102: 1442-7. PMID 15671181 DOI: 10.1073/Pnas.0409532102 |
0.766 |
|
2005 |
Ren XR, Reiter E, Ahn S, Kim J, Chen W, Lefkowitz RJ. Different G protein-coupled receptor kinases govern G protein and beta-arrestin-mediated signaling of V2 vasopressin receptor. Proceedings of the National Academy of Sciences of the United States of America. 102: 1448-53. PMID 15671180 DOI: 10.1073/Pnas.0409534102 |
0.813 |
|
2005 |
Hunton DL, Barnes WG, Kim J, Ren XR, Violin JD, Reiter E, Milligan G, Patel DD, Lefkowitz RJ. Beta-arrestin 2-dependent angiotensin II type 1A receptor-mediated pathway of chemotaxis. Molecular Pharmacology. 67: 1229-36. PMID 15635042 DOI: 10.1124/Mol.104.006270 |
0.738 |
|
2005 |
Barnes WG, Reiter E, Violin JD, Ren XR, Milligan G, Lefkowitz RJ. beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation. The Journal of Biological Chemistry. 280: 8041-50. PMID 15611106 DOI: 10.1074/Jbc.M412924200 |
0.745 |
|
2004 |
Chen W, Ren XR, Nelson CD, Barak LS, Chen JK, Beachy PA, de Sauvage F, Lefkowitz RJ. Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2. Science (New York, N.Y.). 306: 2257-60. PMID 15618519 DOI: 10.1126/Science.1104135 |
0.797 |
|
2004 |
Ren XR, Ming GL, Xie Y, Hong Y, Sun DM, Zhao ZQ, Feng Z, Wang Q, Shim S, Chen ZF, Song HJ, Mei L, Xiong WC. Focal adhesion kinase in netrin-1 signaling. Nature Neuroscience. 7: 1204-12. PMID 15494733 DOI: 10.1038/nn1330 |
0.38 |
|
2001 |
Wong K, Ren XR, Huang YZ, Xie Y, Liu G, Saito H, Tang H, Wen L, Brady-Kalnay SM, Mei L, Wu JY, Xiong WC, Rao Y. Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway. Cell. 107: 209-21. PMID 11672528 DOI: 10.1016/S0092-8674(01)00530-X |
0.338 |
|
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