| Year |
Citation |
Score |
| 2014 |
Pakkanen SA, Raekallio MR, Mykkänen AK, Salla KM, de Vries A, Vuorilehto L, Scheinin M, Vainio OM. Detomidine and the combination of detomidine and MK-467, a peripheral alpha-2 adrenoceptor antagonist, as premedication in horses anaesthetized with isoflurane. Veterinary Anaesthesia and Analgesia. PMID 25529045 DOI: 10.1111/vaa.12238 |
0.403 |
|
| 2010 |
Young S, Vainio M, Scheinin M, Dukat M. Antinociceptive synergism of MD-354 and clonidine. Part II. The alpha-adrenoceptor component. Basic & Clinical Pharmacology & Toxicology. 107: 690-7. PMID 20353485 DOI: 10.1111/j.1742-7843.2010.00563.x |
0.454 |
|
| 2010 |
Rozwandowicz-Jansen A, Laurila J, Martikkala E, Frang H, Hemmilä I, Scheinin M, Hänninen P, Härmä H. Homogeneous GTP binding assay employing QRET technology. Journal of Biomolecular Screening. 15: 261-7. PMID 20103692 DOI: 10.1177/1087057109358921 |
0.32 |
|
| 2008 |
Gentili F, Cardinaletti C, Vesprini C, Carrieri A, Ghelfi F, Farande A, Giannella M, Piergentili A, Quaglia W, Laurila JM, Huhtinen A, Scheinin M, Pigini M. Alpha2-adrenoreceptors profile modulation. 4. From antagonist to agonist behavior. Journal of Medicinal Chemistry. 51: 4289-99. PMID 18578476 DOI: 10.1021/jm800250z |
0.438 |
|
| 2008 |
Fagerholm V, Scheinin M, Haaparanta M. alpha2A-adrenoceptor antagonism increases insulin secretion and synergistically augments the insulinotropic effect of glibenclamide in mice. British Journal of Pharmacology. 154: 1287-96. PMID 18493247 DOI: 10.1038/bjp.2008.186 |
0.316 |
|
| 2008 |
Huhtinen A, Scheinin M. Expression and characterization of the human alpha 2B-adrenoceptor in a vascular smooth muscle cell line. European Journal of Pharmacology. 587: 48-56. PMID 18456256 DOI: 10.1016/j.ejphar.2008.03.049 |
0.356 |
|
| 2007 |
Kurnik D, Muszkat M, Sofowora GG, Friedman EA, Dupont WD, Scheinin M, Wood AJ, Stein CM. Ethnic and genetic determinants of cardiovascular response to the selective alpha 2-adrenoceptor agonist dexmedetomidine. Hypertension (Dallas, Tex. : 1979). 51: 406-11. PMID 18071056 DOI: 10.1161/Hypertensionaha.107.098939 |
0.346 |
|
| 2007 |
Laurila JM, Xhaard H, Ruuskanen JO, Rantanen MJ, Karlsson HK, Johnson MS, Scheinin M. The second extracellular loop of alpha2A-adrenoceptors contributes to the binding of yohimbine analogues. British Journal of Pharmacology. 151: 1293-304. PMID 17558432 DOI: 10.1038/sj.bjp.0707330 |
0.369 |
|
| 2006 |
Snapir A, Posti J, Kentala E, Koskenvuo J, Sundell J, Tuunanen H, Hakala K, Scheinin H, Knuuti J, Scheinin M. Effects of low and high plasma concentrations of dexmedetomidine on myocardial perfusion and cardiac function in healthy male subjects. Anesthesiology. 105: 902-10; quiz 1069-70. PMID 17065883 DOI: 10.1097/00000542-200611000-00010 |
0.33 |
|
| 2006 |
Ozdoğan UK, Lähdesmäki J, Scheinin M. The analgesic efficacy of partial opioid agonists is increased in mice with targeted inactivation of the alpha2A-adrenoceptor gene. European Journal of Pharmacology. 529: 105-13. PMID 16325800 DOI: 10.1016/j.ejphar.2005.10.029 |
0.369 |
|
| 2005 |
Ruuskanen JO, Peitsaro N, Kaslin JV, Panula P, Scheinin M. Expression and function of alpha-adrenoceptors in zebrafish: drug effects, mRNA and receptor distributions. Journal of Neurochemistry. 94: 1559-69. PMID 16000146 DOI: 10.1111/j.1471-4159.2005.03305.x |
0.465 |
|
| 2005 |
Juhila J, Honkanen A, Sallinen J, Haapalinna A, Korpi ER, Scheinin M. alpha(2A)-Adrenoceptors regulate d-amphetamine-induced hyperactivity and behavioural sensitization in mice. European Journal of Pharmacology. 517: 74-83. PMID 15978573 DOI: 10.1016/J.EJPHAR.2005.05.022 |
0.363 |
|
| 2005 |
Talke P, Stapelfeldt C, Lobo E, Brown R, Scheinin M, Snapir A. Alpha-2B adrenoceptor polymorphism and peripheral vasoconstriction. Pharmacogenetics and Genomics. 15: 357-63. PMID 15864138 DOI: 10.1097/01213011-200505000-00012 |
0.421 |
|
| 2005 |
Talke P, Stapelfeldt C, Lobo E, Brown R, Scheinin M, Snapir A. Effect of alpha2B-adrenoceptor polymorphism on peripheral vasoconstriction in healthy volunteers. Anesthesiology. 102: 536-42. PMID 15731590 DOI: 10.1097/00000542-200503000-00010 |
0.362 |
|
| 2005 |
Ruuskanen JO, Laurila J, Xhaard H, Rantanen VV, Vuoriluoto K, Wurster S, Marjamäki A, Vainio M, Johnson MS, Scheinin M. Conserved structural, pharmacological and functional properties among the three human and five zebrafish alpha 2-adrenoceptors. British Journal of Pharmacology. 144: 165-77. PMID 15655522 DOI: 10.1038/sj.bjp.0706057 |
0.433 |
|
| 2005 |
Flordellis C, Manolis A, Scheinin M, Paris H. Clinical and pharmacological significance of alpha2-adrenoceptor polymorphisms in cardiovascular diseases. International Journal of Cardiology. 97: 367-72. PMID 15561320 DOI: 10.1016/J.IJCARD.2003.10.014 |
0.409 |
|
| 2005 |
Ozdogan UK, Lähdesmäki J, Hakala K, Scheinin M. The involvement of alpha 2A-adrenoceptors in morphine analgesia, tolerance and withdrawal in mice. European Journal of Pharmacology. 497: 161-71. PMID 15306201 DOI: 10.1016/J.EJPHAR.2004.06.051 |
0.339 |
|
| 2005 |
Stapelfeldt C, Talke P, Lobo E, Brown R, Scheinin M, Snapir A. Alpha-2B adrenoceptor polymorphism: effects on peripheral vasoconstriction in healthy volunteers European Journal of Anaesthesiology. 22: 54. DOI: 10.1097/00003643-200505001-00189 |
0.34 |
|
| 2004 |
Olli-Lähdesmäki T, Tiger M, Vainio M, Scheinin M, Kallio J. Ligand-induced alpha2-adrenoceptor endocytosis: relationship to Gi protein activation. Biochemical and Biophysical Research Communications. 321: 226-33. PMID 15358239 DOI: 10.1016/J.BBRC.2004.06.131 |
0.338 |
|
| 2004 |
Fagerholm V, Philipp M, Hein L, Scheinin M. [Ethyl-3H]RS-79948-197 alpha2-adrenoceptor autoradiography validation in alpha2-adrenoceptor knockout mice. European Journal of Pharmacology. 497: 301-9. PMID 15336948 DOI: 10.1016/J.Ejphar.2004.06.065 |
0.37 |
|
| 2004 |
Mansikka H, Lähdesmäki J, Scheinin M, Pertovaara A. Alpha(2A) adrenoceptors contribute to feedback inhibition of capsaicin-induced hyperalgesia. Anesthesiology. 101: 185-90. PMID 15220790 DOI: 10.1097/00000542-200407000-00029 |
0.406 |
|
| 2004 |
Lähdesmäki J, Sallinen J, MacDonald E, Scheinin M. Alpha2A-adrenoceptors are important modulators of the effects of D-amphetamine on startle reactivity and brain monoamines. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 1282-93. PMID 15039766 DOI: 10.1038/sj.npp.1300428 |
0.377 |
|
| 2004 |
Ozdoğan UK, Lähdesmäki J, Mansikka H, Scheinin M. Loss of amitriptyline analgesia in alpha 2A-adrenoceptor deficient mice. European Journal of Pharmacology. 485: 193-6. PMID 14757140 DOI: 10.1016/J.EJPHAR.2003.11.047 |
0.383 |
|
| 2004 |
Ruuskanen JO, Xhaard H, Marjamäki A, Salaneck E, Salminen T, Yan YL, Postlethwait JH, Johnson MS, Larhammar D, Scheinin M. Identification of duplicated fourth alpha2-adrenergic receptor subtype by cloning and mapping of five receptor genes in zebrafish. Molecular Biology and Evolution. 21: 14-28. PMID 12949138 DOI: 10.1093/molbev/msg224 |
0.413 |
|
| 2003 |
Sen S, Jaakola VP, Heimo H, Engström M, Larjomaa P, Scheinin M, Lundstrom K, Goldman A. Functional expression and direct visualization of the human alpha 2B -adrenergic receptor and alpha 2B -AR-green fluorescent fusion protein in mammalian cell using Semliki Forest virus vectors. Protein Expression and Purification. 32: 265-75. PMID 14965773 DOI: 10.1016/J.Pep.2003.08.006 |
0.393 |
|
| 2003 |
Ge H, Olli-Lähdesmäki T, Kallio J, Scheinin M. alpha 2B-Adrenoceptor levels govern agonist and inverse agonist responses in PC12 cells. Biochemical and Biophysical Research Communications. 308: 12-8. PMID 12890472 DOI: 10.1016/S0006-291X(03)01320-2 |
0.39 |
|
| 2003 |
Ge H, Scheinin M, Kallio J. Constitutive precoupling to G(i) and increased agonist potency in the alpha(2B)-adrenoceptor. Biochemical and Biophysical Research Communications. 306: 959-65. PMID 12821136 DOI: 10.1016/S0006-291X(03)01094-5 |
0.338 |
|
| 2003 |
Olli-Lähdesmäki T, Scheinin M, Pohjanoksa K, Kallio J. Agonist-dependent trafficking of alpha2-adrenoceptor subtypes: dependence on receptor subtype and employed agonist. European Journal of Cell Biology. 82: 231-9. PMID 12800978 DOI: 10.1078/0171-9335-00311 |
0.357 |
|
| 2003 |
Lähdesmäki J, Scheinin M, Pertovaara A, Mansikka H. The alpha2A-adrenoceptor subtype is not involved in inflammatory hyperalgesia or morphine-induced antinociception. European Journal of Pharmacology. 468: 183-9. PMID 12754056 DOI: 10.1016/S0014-2999(03)01677-7 |
0.31 |
|
| 2003 |
Lähdesmäki J, Sallinen J, MacDonald E, Sirviö J, Scheinin M. Alpha2-adrenergic drug effects on brain monoamines, locomotion, and body temperature are largely abolished in mice lacking the alpha2A-adrenoceptor subtype. Neuropharmacology. 44: 882-92. PMID 12726820 DOI: 10.1016/S0028-3908(03)00080-7 |
0.449 |
|
| 2003 |
Holmberg M, Fagerholm V, Scheinin M. Regional distribution of α2C-adrenoceptors in brain and spinal cord of control mice and transgenic mice overexpressing the α2C-subtype: An autoradiographic study with [3H]RX821002 and [3H]rauwolscine Neuroscience. 117: 875-898. PMID 12654340 DOI: 10.1016/S0306-4522(02)00966-1 |
0.45 |
|
| 2003 |
Juhila J, Haapalinna A, Sirviö J, Sallinen J, Honkanen A, Korpi ER, Scheinin M. The alpha2-adrenoceptor antagonist atipamezole reduces the development and expression of d-amphetamine-induced behavioural sensitization. Naunyn-Schmiedeberg's Archives of Pharmacology. 367: 274-80. PMID 12644900 DOI: 10.1007/s00210-003-0695-6 |
0.316 |
|
| 2002 |
Puoliväli J, Björklund M, Holmberg M, Ihalainen JA, Scheinin M, Tanila H. Alpha 2C-adrenoceptor mediated regulation of cortical EEG arousal. Neuropharmacology. 43: 1305-12. PMID 12527480 DOI: 10.1016/S0028-3908(02)00305-2 |
0.438 |
|
| 2002 |
Sen S, Jaakola VP, Heimo H, Kivelä P, Scheinin M, Lundstrom K, Goldman A. Development of a scintiplate assay for recombinant human alpha(2B)-adrenergic receptor. Analytical Biochemistry. 307: 280-6. PMID 12202245 DOI: 10.1016/S0003-2697(02)00041-6 |
0.339 |
|
| 2002 |
Lähdesmäki J, Sallinen J, MacDonald E, Kobilka BK, Fagerholm V, Scheinin M. Behavioral and neurochemical characterization of alpha(2A)-adrenergic receptor knockout mice. Neuroscience. 113: 289-99. PMID 12127086 DOI: 10.1016/S0306-4522(02)00185-9 |
0.587 |
|
| 2002 |
Taraviras S, Olli-Lähdesmäki T, Lymperopoulos A, Charitonidou D, Mavroidis M, Kallio J, Scheinin M, Flordellis C. Subtype-specific neuronal differentiation of PC12 cells transfected with alpha2-adrenergic receptors. European Journal of Cell Biology. 81: 363-74. PMID 12113477 DOI: 10.1078/0171-9335-00250 |
0.39 |
|
| 2001 |
Ihalainen JA, Tanila H, Scheinin M, Riekkinen P. alpha(2C)-Adrenoceptors modulate the effect of methylphenidate on response rate and discrimination accuracy in an operant test. Brain Research Bulletin. 54: 553-7. PMID 11397547 DOI: 10.1016/S0361-9230(01)00449-X |
0.348 |
|
| 2001 |
Frang H, Cockcroft V, Karskela T, Scheinin M, Marjamäki A. Phenoxybenzamine binding reveals the helical orientation of the third transmembrane domain of adrenergic receptors. The Journal of Biological Chemistry. 276: 31279-84. PMID 11395517 DOI: 10.1074/JBC.M104167200 |
0.414 |
|
| 2001 |
Liitti S, Matikainen MT, Scheinin M, Glumoff T, Goldman A. Immunoaffinity purification and reconstitution of human alpha(2)-adrenergic receptor subtype C2 into phospholipid vesicles. Protein Expression and Purification. 22: 1-10. PMID 11388793 DOI: 10.1006/Prep.2001.1410 |
0.353 |
|
| 2001 |
Scheinin M, Sallinen J, Haapalinna A. Evaluation of the alpha2C-adrenoceptor as a neuropsychiatric drug target studies in transgenic mouse models. Life Sciences. 68: 2277-85. PMID 11358337 DOI: 10.1016/S0024-3205(01)01016-5 |
0.344 |
|
| 2001 |
Nyrönen T, Pihlavisto M, Peltonen JM, Hoffrén AM, Varis M, Salminen T, Wurster S, Marjamäki A, Kanerva L, Katainen E, Laaksonen L, Savola JM, Scheinin M, Johnson MS. Molecular mechanism for agonist-promoted alpha(2A)-adrenoceptor activation by norepinephrine and epinephrine. Molecular Pharmacology. 59: 1343-54. PMID 11306720 DOI: 10.1124/MOL.59.5.1343 |
0.366 |
|
| 2000 |
Meyer H, Palchaudhuri M, Scheinin M, Flügge G. Regulation of alpha(2A)-adrenoceptor expression by chronic stress in neurons of the brain stem. Brain Research. 880: 147-58. PMID 11032999 DOI: 10.1016/S0006-8993(00)02787-6 |
0.327 |
|
| 2000 |
Cockcroft V, Frang H, Pihlavisto M, Marjamäki A, Scheinin M. Ligand recognition of serine-cysteine amino acid exchanges in transmembrane domain 5 of alpha2-adrenergic receptors by UK 14,304. Journal of Neurochemistry. 74: 1705-10. PMID 10737629 DOI: 10.1046/j.1471-4159.2000.0741705.x |
0.371 |
|
| 2000 |
Pihlavisto M, Scheinin M. Functional assessment of recombinant human alpha(2)-adrenoceptor subtypes with cytosensor microphysiometry. European Journal of Pharmacology. 385: 247-53. PMID 10607883 DOI: 10.1016/S0014-2999(99)00715-3 |
0.434 |
|
| 2000 |
Scheinin M, Pihlavisto M. Molecular pharmacology of alpha2-adrenoceptor agonists Best Practice & Research Clinical Anaesthesiology. 14: 247-260. DOI: 10.1053/BEAN.2000.0080 |
0.412 |
|
| 1999 |
Sallinen J, Haapalinna A, MacDonald E, Viitamaa T, Lähdesmäki J, Rybnikova E, Pelto-Huikko M, Kobilka BK, Scheinin M. Genetic alteration of the alpha2-adrenoceptor subtype c in mice affects the development of behavioral despair and stress-induced increases in plasma corticosterone levels. Molecular Psychiatry. 4: 443-52. PMID 10523817 DOI: 10.1038/Sj.Mp.4000543 |
0.561 |
|
| 1999 |
Holmberg M, Scheinin M, Kurose H, Miettinen R. Adrenergic α(2C)-receptors reside in rat striatal GABAergic projection neurons: Comparison of radioligand binding and immunohistochemistry Neuroscience. 93: 1323-1333. PMID 10501456 DOI: 10.1016/S0306-4522(99)00260-2 |
0.494 |
|
| 1999 |
Salminen T, Varis M, Nyrönen T, Pihlavisto M, Hoffrén AM, Lönnberg T, Marjamäki A, Frang H, Savola JM, Scheinin M, Johnson MS. Three-dimensional models of alpha(2A)-adrenergic receptor complexes provide a structural explanation for ligand binding. The Journal of Biological Chemistry. 274: 23405-13. PMID 10438518 DOI: 10.1074/jbc.274.33.23405 |
0.363 |
|
| 1999 |
Jansson CC, Pohjanoksa K, Lang J, Wurster S, Savola JM, Scheinin M. Alpha2-adrenoceptor agonists stimulate high-affinity GTPase activity in a receptor subtype-selective manner. European Journal of Pharmacology. 374: 137-46. PMID 10422650 DOI: 10.1016/S0014-2999(99)00306-4 |
0.401 |
|
| 1999 |
Marjamäki A, Frang H, Pihlavisto M, Hoffrén AM, Salminen T, Johnson MS, Kallio J, Javitch JA, Scheinin M. Chloroethylclonidine and 2-aminoethyl methanethiosulfonate recognize two different conformations of the human alpha(2A)-adrenergic receptor. The Journal of Biological Chemistry. 274: 21867-72. PMID 10419505 DOI: 10.1074/Jbc.274.31.21867 |
0.355 |
|
| 1999 |
Björklund M, Sirviö J, Sallinen J, Scheinin M, Kobilka BK, Riekkinen P. Alpha2C-adrenoceptor overexpression disrupts execution of spatial and non-spatial search patterns. Neuroscience. 88: 1187-98. PMID 10336129 DOI: 10.1016/S0306-4522(98)00306-6 |
0.429 |
|
| 1999 |
Tanila H, Mustonen K, Sallinen J, Scheinin M, Riekkinen P. Role of alpha2C-adrenoceptor subtype in spatial working memory as revealed by mice with targeted disruption of the alpha2C-adrenoceptor gene. The European Journal of Neuroscience. 11: 599-603. PMID 10051760 DOI: 10.1046/j.1460-9568.1999.00464.x |
0.303 |
|
| 1999 |
Pihlavisto M, Sjöholm B, Scheinin M, Wurster S. Modulation of agonist binding to recombinant human alpha2-adrenoceptors by sodium ions. Biochimica Et Biophysica Acta. 1448: 135-46. PMID 9824686 DOI: 10.1016/S0167-4889(98)00118-9 |
0.332 |
|
| 1998 |
Peltonen JM, Pihlavisto M, Scheinin M. Subtype-specific stimulation of [35S]GTPgammaS binding by recombinant alpha2-adrenoceptors. European Journal of Pharmacology. 355: 275-9. PMID 9760042 DOI: 10.1016/S0014-2999(98)00518-4 |
0.347 |
|
| 1998 |
Björklund M, Sirviö J, Puoliväli J, Sallinen J, Jäkälä P, Scheinin M, Kobilka BK, Riekkinen P. Alpha2C-adrenoceptor-overexpressing mice are impaired in executing nonspatial and spatial escape strategies. Molecular Pharmacology. 54: 569-76. PMID 9730916 DOI: 10.1124/Mol.54.3.569 |
0.586 |
|
| 1998 |
Sallinen J, Haapalinna A, Viitamaa T, Kobilka BK, Scheinin M. D-amphetamine and L-5-hydroxytryptophan-induced behaviours in mice with genetically-altered expression of the alpha2C-adrenergic receptor subtype. Neuroscience. 86: 959-65. PMID 9692731 DOI: 10.1016/S0306-4522(98)00100-6 |
0.535 |
|
| 1998 |
Heinonen P, Koskua K, Pihlavisto M, Marjamäki A, Cockcroft V, Savola JM, Scheinin M, Lönnberg H. A series of 6-(omega-methanesulfonylthioalkoxy)-2-N-methyl- 1,2,3, 4-tetrahydroisoquinolines: cysteine-reactive molecular yardsticks for probing alpha2-adrenergic receptors. Bioconjugate Chemistry. 9: 358-64. PMID 9576810 DOI: 10.1021/BC970193O |
0.363 |
|
| 1998 |
Sallinen J, Haapalinna A, Viitamaa T, Kobilka BK, Scheinin M. Adrenergic alpha2C-receptors modulate the acoustic startle reflex, prepulse inhibition, and aggression in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 3035-42. PMID 9526020 |
0.552 |
|
| 1998 |
Marjamaki A, Pihlavisto M, Cockcroft V, Heinonen P, Savola JM, Scheinin M. Chloroethylclonidine binds irreversibly to exposed cysteines in the fifth membrane-spanning domain of the human alpha2A-adrenergic receptor. Molecular Pharmacology. 53: 370-6. PMID 9495800 DOI: 10.1124/MOL.53.3.370 |
0.362 |
|
| 1998 |
Virolainen S, Jansson CC, Scheinin M. Assessment of alpha2-adrenoceptor antagonist potency with GTPase assay. European Journal of Pharmacology. 338: 293-6. PMID 9424024 DOI: 10.1016/S0014-2999(97)81933-4 |
0.401 |
|
| 1997 |
MacDonald E, Kobilka BK, Scheinin M. Gene targeting--homing in on alpha 2-adrenoceptor-subtype function. Trends in Pharmacological Sciences. 18: 211-9. PMID 9227000 DOI: 10.1016/S0165-6147(97)01063-8 |
0.607 |
|
| 1997 |
Sallinen J, Link RE, Haapalinna A, Viitamaa T, Kulatunga M, Sjöholm B, Macdonald E, Pelto-Huikko M, Leino T, Barsh GS, Kobilka BK, Scheinin M. Genetic alteration of alpha 2C-adrenoceptor expression in mice: influence on locomotor, hypothermic, and neurochemical effects of dexmedetomidine, a subtype-nonselective alpha 2-adrenoceptor agonist. Molecular Pharmacology. 51: 36-46. PMID 9016344 DOI: 10.1124/Mol.51.1.36 |
0.618 |
|
| 1996 |
Aantaa R, Marjamäki A, Scheinin M. Molecular pharmacology of alpha 2-adrenoceptor subtypes. Annals of Medicine. 27: 439-49. PMID 8519505 DOI: 10.3109/07853899709002452 |
0.467 |
|
| 1995 |
Halme M, Sjöholm B, Savola JM, Scheinin M. Recombinant human alpha 2-adrenoceptor subtypes: comparison of [3H]rauwolscine, [3H]atipamezole and [3H]RX821002 as radioligands. Biochimica Et Biophysica Acta. 1266: 207-14. PMID 7742388 DOI: 10.1016/0167-4889(95)90410-I |
0.424 |
|
| 1994 |
Scheinin M, Lomasney JW, Hayden-Hixson DM, Schambra UB, Caron MG, Lefkowitz RJ, Fremeau RT. Distribution of alpha 2-adrenergic receptor subtype gene expression in rat brain. Brain Research. Molecular Brain Research. 21: 133-49. PMID 8164514 DOI: 10.1016/0169-328X(94)90386-7 |
0.683 |
|
| 1994 |
Marjamäki A, Pohjanoksa K, Ala-Uotila S, Sizmann D, Oker-Blom C, Kurose H, Scheinin M. Similar ligand binding in recombinant human α2C2-adrenoceptors produced in mammalian, insect and yeast cells European Journal of Pharmacology. 267: 117-121. PMID 7911432 DOI: 10.1016/0922-4106(94)90232-1 |
0.488 |
|
| 1994 |
Jansson CC, Marjamäki A, Luomala K, Savola JM, Scheinin M, Akerman KE. Coupling of human alpha 2-adrenoceptor subtypes to regulation of cAMP production in transfected S115 cells. European Journal of Pharmacology. 266: 165-74. PMID 7908883 DOI: 10.1016/0922-4106(94)90106-6 |
0.446 |
|
| 1993 |
Aantaa R, Scheinin M. Alpha 2-adrenergic agents in anaesthesia. Acta Anaesthesiologica Scandinavica. 37: 433-48. PMID 8395129 DOI: 10.1111/j.1399-6576.1993.tb03743.x |
0.373 |
|
| 1993 |
Koulu M, Pesonen U, Koskinen S, Scheinin H, Virtanen R, Scheinin M. Reduced turnover of dopamine and 5-hydroxytryptamine in discrete dopaminergic, noradrenergic and serotonergic rat brain areas after acutely administered medetomidine, a selective alpha 2-adrenoceptor agonist. Pharmacology & Toxicology. 72: 182-7. PMID 8100065 DOI: 10.1111/J.1600-0773.1993.TB00313.X |
0.315 |
|
| 1993 |
Marjamäki A, Luomala K, Ala-Uotila S, Scheinin M. Use of recombinant human alpha 2-adrenoceptors to characterize subtype selectively of antagonist binding. European Journal of Pharmacology. 246: 219-26. PMID 7901041 DOI: 10.1016/0922-4106(93)90034-7 |
0.477 |
|
| 1993 |
Svensson SPS, Bailey TJ, Pepperl DJ, Grundstrom N, Ala-Uotila S, Scheinin M, Karlsson JOG, Regan JW. Cloning and expression of a fish α2-adrenoceptor British Journal of Pharmacology. 110: 54-60. PMID 7693288 DOI: 10.1111/J.1476-5381.1993.Tb13771.X |
0.497 |
|
| 1993 |
Scheinin M. Alpha2-adrenergic agents in anaesthesia: Mechanisms of action Acta Anaesthesiologica Scandinavica. 37: 165-169. DOI: 10.1111/j.1399-6576.1993.tb03668.x |
0.349 |
|
| 1992 |
Sjöholm B, Voutilainen R, Luomala K, Savola JM, Scheinin M. Characterization of [3H]atipamezole as a radioligand for alpha 2-adrenoceptors. European Journal of Pharmacology. 215: 109-17. PMID 1355439 DOI: 10.1016/0014-2999(92)90615-B |
0.352 |
|
| 1992 |
Scheinin M, Schwinn DA. The locus coeruleus. Site of hypnotic actions of alpha 2-adrenoceptor agonists? Anesthesiology. 76: 873-5. PMID 1350888 DOI: 10.1097/00000542-199206000-00001 |
0.594 |
|
| 1992 |
Perälä M, Hirvonen H, Kalimo H, Ala-Uotila S, Regan JW, Akerman KE, Scheinin M. Differential expression of two alpha 2-adrenergic receptor subtype mRNAs in human tissues. Brain Research. Molecular Brain Research. 16: 57-63. PMID 1334200 DOI: 10.1016/0169-328X(92)90193-F |
0.631 |
|
| 1992 |
Pesonen U, Miettinen T, Scheinin M, Koulu M. Alpha 2-adrenoceptor density in forebrain areas of Zucker rats: no effect of genetic obesity or antiglucocorticoid treatment. Brain Research. 574: 353-6. PMID 1322226 DOI: 10.1016/0006-8993(92)90841-V |
0.325 |
|
| 1992 |
Marjamäki A, Ala-Uotila S, Luomala K, Perälä M, Jansson C, Jalkanen M, Regan JW, Scheinin M. Stable expression of recombinant human α2-adrenoceptor subtypes in two mammalian cell lines: characterization with [3H]rauwolscine binding, inhibition of adenylate cyclase and RNase protection assay Bba - Molecular Cell Research. 1134: 169-177. PMID 1313304 DOI: 10.1016/0167-4889(92)90041-9 |
0.536 |
|
| 1991 |
Karhuvaara S, Kallio A, Salonen M, Tuominen J, Scheinin M. Rapid reversal of alpha 2-adrenoceptor agonist effects by atipamezole in human volunteers. British Journal of Clinical Pharmacology. 31: 160-5. PMID 1675577 DOI: 10.1111/J.1365-2125.1991.TB05505.X |
0.311 |
|
| 1990 |
Karhuvaara S, Kallio A, Koulu M, Scheinin H, Scheinin M. No involvement of alpha 2-adrenoceptors in the regulation of basal prolactin secretion in healthy men. Psychoneuroendocrinology. 15: 125-9. PMID 1972797 DOI: 10.1016/0306-4530(90)90020-A |
0.392 |
|
| 1989 |
MacDonald E, Scheinin H, Scheinin M. Behavioural and neurochemical effects of medetomidine, a novel veterinary sedative. European Journal of Pharmacology. 158: 119-27. PMID 2906007 DOI: 10.1016/0014-2999(88)90260-9 |
0.302 |
|
| 1989 |
Scheinin H, Virtanen R, MacDonald E, Lammintausta R, Scheinin M. Medetomidine--a novel alpha 2-adrenoceptor agonist: a review of its pharmacodynamic effects. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 13: 635-51. PMID 2571177 DOI: 10.1016/0278-5846(89)90051-1 |
0.438 |
|
| 1988 |
Scheinin H, MacDonald E, Scheinin M. Behavioural and neurochemical effects of antipamezole, a novel alpha 2-adrenoceptor antagonist. European Journal of Pharmacology. 151: 35-42. PMID 2901363 DOI: 10.1016/0014-2999(88)90689-9 |
0.395 |
|
| 1988 |
Kallio A, Koulu M, Scheinin H, Viikari J, Scheinin M. Acute effects of medetomidine, a selective alpha 2-adrenoceptor agonist, on anterior pituitary hormone and cortisol secretion in man. Acta Endocrinologica. 119: 11-5. PMID 2901180 DOI: 10.1530/ACTA.0.1190011 |
0.359 |
|
| 1988 |
Scheinin M, Kallio A, Koulu M, Viikari J, Scheinin H. Sedative and cardiovascular effects of medetomidine, a novel selective alpha 2-adrenoceptor agonist, in healthy volunteers. British Journal of Clinical Pharmacology. 24: 443-51. PMID 2891369 DOI: 10.1111/J.1365-2125.1987.TB03196.X |
0.378 |
|
| 1988 |
Hauger RL, Scheinin M, Siever LJ, Linnoila M, Potter WZ. Dissociation of norepinephrine turnover from alpha-2 responses after clorgiline. Clinical Pharmacology and Therapeutics. 43: 32-8. PMID 2826065 DOI: 10.1038/clpt.1988.8 |
0.338 |
|
| 1986 |
Scheinin H, Virtanen R, Scheinin M. alpha 2-Adrenoceptor agonists decrease free 3-methoxy-4-hydroxyphenylglycol in rat cerebrospinal fluid. European Journal of Pharmacology. 123: 115-21. PMID 2872072 DOI: 10.1016/0014-2999(86)90695-3 |
0.301 |
|
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