Jinpeng Sun - Publications

2007-2011 Duke University, Durham, NC 
 2011- Shandong University, Jinan Shi, Shandong Sheng, China 
 2018- Beijing University, Beijing, Beijing Shi, China 

106 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Shen Q, Tang X, Wen X, Cheng S, Xiao P, Zang SK, Shen DD, Jiang L, Zheng Y, Zhang H, Xu H, Mao C, Zhang M, Hu W, Sun JP, et al. Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2310120. PMID 38647423 DOI: 10.1002/advs.202310120  0.491
2024 Wang KY, Gao MX, Qi HB, An WT, Lin JY, Ning SL, Yang F, Xiao P, Cheng J, Pan W, Cheng QX, Wang J, Fang L, Sun JP, Yu X. Differential contributions of G protein- or arrestin subtype-mediated signalling underlie urocortin 3-induced somatostatin secretion in pancreatic δ cells. British Journal of Pharmacology. PMID 38613153 DOI: 10.1111/bph.16351  0.808
2024 Li X, Zhang X, Wen X, Zhang D, Qu C, Miao X, Zhang W, Zhang R, Liu G, Xiao P, Sun JP, Gong W. Structural basis for ligand recognition and activation of the prostanoid receptors. Cell Reports. 43: 113893. PMID 38446662 DOI: 10.1016/j.celrep.2024.113893  0.769
2024 Zhou Z, Zhang W, Zhao F, Sun Y, Wang N, Cheng J, Zhan P, Yang F, Sun JP, Liu X, Kang D. Structure-Based Design of Novel G-Protein-Coupled Receptor TAAR1 Agonists as Potential Antipsychotic Drug Candidates. Journal of Medicinal Chemistry. PMID 38416116 DOI: 10.1021/acs.jmedchem.4c00195  0.323
2024 Mao C, Zhao RJ, Dong YJ, Gao M, Chen LN, Zhang C, Xiao P, Guo J, Qin J, Shen DD, Ji SY, Zang SK, Zhang H, Wang WW, Shen Q, ... Sun JP, et al. Conformational transitions and activation of the adhesion receptor CD97. Molecular Cell. PMID 38215752 DOI: 10.1016/j.molcel.2023.12.020  0.519
2023 Shang P, Rong N, Jiang JJ, Cheng J, Zhang MH, Kang D, Qi L, Guo L, Yang GM, Liu Q, Zhou Z, Li XB, Zhu KK, Meng QB, Han X, ... ... Sun JP, et al. Structural and signaling mechanisms of TAAR1 enabled preferential agonist design. Cell. PMID 37963465 DOI: 10.1016/j.cell.2023.10.014  0.378
2023 Yang Z, Wang JY, Yang F, Zhu KK, Wang GP, Guan Y, Ning SL, Lu Y, Li Y, Zhang C, Zheng Y, Zhou SH, Wang XW, Wang MW, Xiao P, ... ... Sun JP, et al. Structure of GPR101-Gs enables identification of ligands with rejuvenating potential. Nature Chemical Biology. PMID 37945893 DOI: 10.1038/s41589-023-01456-6  0.558
2023 Xu Z, Guo L, Yu J, Shen S, Wu C, Zhang W, Zhao C, Deng Y, Tian X, Feng Y, Hou H, Su L, Wang H, Guo S, Wang H, ... ... Sun JP, et al. Ligand recognition and G protein coupling of trace amine receptor TAAR1. Nature. PMID 37935376 DOI: 10.1038/s41586-023-06804-z  0.425
2023 Guo L, Zhang Y, Fang G, Tie L, Zhuang Y, Xue C, Liu Q, Zhang M, Zhu K, You C, Xu P, Yuan Q, Zhang C, Liu L, Rong N, ... ... Sun JP, et al. Ligand recognition and G protein coupling of the human itch receptor MRGPRX1. Nature Communications. 14: 5004. PMID 37591889 DOI: 10.1038/s41467-023-40705-z  0.428
2023 Huang SM, Xiong MY, Liu L, Mu J, Wang MW, Jia YL, Cai K, Tie L, Zhang C, Cao S, Wen X, Wang JL, Guo SC, Li Y, Qu CX, ... ... Sun JP, et al. Single hormone or synthetic agonist induces G/G coupling selectivity of EP receptors via distinct binding modes and propagating paths. Proceedings of the National Academy of Sciences of the United States of America. 120: e2216329120. PMID 37478163 DOI: 10.1073/pnas.2216329120  0.813
2023 Pei Y, Wen X, Guo SC, Yang ZS, Zhang R, Xiao P, Sun JP. Structural insight into the selective agonist ST1936 binding of serotonin receptor 5-HT6. Biochemical and Biophysical Research Communications. 671: 327-334. PMID 37327704 DOI: 10.1016/j.bbrc.2023.05.126  0.507
2023 Guo L, Cheng J, Lian S, Liu Q, Lu Y, Zheng Y, Zhu K, Zhang M, Kong Y, Zhang C, Rong N, Zhuang Y, Fang G, Jiang J, Zhang T, ... ... Sun JP, et al. Structural basis of amine odorant perception by a mammal olfactory receptor. Nature. PMID 37225986 DOI: 10.1038/s41586-023-06106-4  0.388
2023 Guan Y, Du HB, Yang Z, Wang YZ, Ren R, Liu WW, Zhang C, Zhang JH, An WT, Li NN, Zeng XX, Li J, Sun YX, Wang YF, Yang F, ... ... Sun JP, et al. Deafness-Associated ADGRV1 Mutation Impairs USH2A Stability through Improper Phosphorylation of WHRN and WDSUB1 Recruitment. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2205993. PMID 37066759 DOI: 10.1002/advs.202205993  0.805
2023 Mao C, Xiao P, Tao XN, Qin J, He QT, Zhang C, Guo SC, Du YQ, Chen LN, Shen DD, Yang ZS, Zhang HQ, Huang SM, He YH, Cheng J, ... ... Sun JP, et al. Unsaturated bond recognition leads to biased signal in a fatty acid receptor. Science (New York, N.Y.). eadd6220. PMID 36862765 DOI: 10.1126/science.add6220  0.798
2022 Lin H, Xiao P, Bu RQ, Guo S, Yang Z, Yuan D, Zhu ZL, Zhang CX, He QT, Zhang C, Ping YQ, Zhao RJ, Ma CS, Liu CH, Zhang XN, ... ... Sun JP, et al. Structures of the ADGRG2-G complex in apo and ligand-bound forms. Nature Chemical Biology. PMID 35982227 DOI: 10.1038/s41589-022-01084-6  0.76
2022 Ma L, Yang F, Wu X, Mao C, Guo L, Miao T, Zang SK, Jiang X, Shen DD, Wei T, Zhou H, Wei Q, Li S, Shu Q, Feng S, ... ... Sun JP, et al. Structural basis and molecular mechanism of biased GPBAR signaling in regulating NSCLC cell growth via YAP activity. Proceedings of the National Academy of Sciences of the United States of America. 119: e2117054119. PMID 35858343 DOI: 10.1073/pnas.2117054119  0.405
2022 Du YQ, Sha XY, Cheng J, Wang J, Lin JY, An WT, Pan W, Zhang LJ, Tao XN, Xu Y, Jia YL, Yang Z, Xiao P, Liu M, Sun JP, et al. Endogenous Lipid-GPR120 Signaling Modulates Pancreatic Islet Homeostasis to Different Extents. Diabetes. PMID 35472681 DOI: 10.2337/db21-0794  0.788
2022 Ping YQ, Xiao P, Yang F, Zhao RJ, Guo SC, Yan X, Wu X, Zhang C, Lu Y, Zhao F, Zhou F, Xi YT, Yin W, Liu FZ, He DF, ... ... Sun JP, et al. Structural basis for the tethered peptide activation of adhesion GPCRs. Nature. PMID 35418678 DOI: 10.1038/s41586-022-04619-y  0.762
2022 Xiao P, Guo S, Wen X, He QT, Lin H, Huang SM, Gou L, Zhang C, Yang Z, Zhong YN, Yang CC, Li Y, Gong Z, Tao XN, Yang ZS, ... ... Sun JP, et al. Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4. Nature. PMID 35418677 DOI: 10.1038/s41586-022-04590-8  0.815
2022 An W, Lin H, Ma L, Zhang C, Zheng Y, Cheng Q, Ma C, Wu X, Zhang Z, Zhong Y, Wang M, He D, Yang Z, Du L, Feng S, ... ... Sun JP, et al. Progesterone activates GPR126 to promote breast cancer development via the Gi pathway. Proceedings of the National Academy of Sciences of the United States of America. 119: e2117004119. PMID 35394864 DOI: 10.1073/pnas.2117004119  0.791
2022 Lu R, Yan X, Fang G, Zhuang Y, Guo L, Zhang C, Wu X, Xiao P, Cao Y, Yang F, Yu X, Sun JP, Zhou JY. A molecular mechanism of UDCA engagement with GPBAR and subsequent G protein interaction revealed by scattered alanine scanning. Biochemical and Biophysical Research Communications. 600: 14-21. PMID 35182970 DOI: 10.1016/j.bbrc.2022.02.030  0.533
2022 Cheng J, Yang Z, Ge XY, Gao MX, Meng R, Xu X, Zhang YQ, Li RZ, Lin JY, Tian ZM, Wang J, Ning SL, Xu YF, Yang F, Gu JK, ... Sun JP, et al. Autonomous sensing of the insulin peptide by an olfactory G protein-coupled receptor modulates glucose metabolism. Cell Metabolism. 34: 240-255.e10. PMID 35108512 DOI: 10.1016/j.cmet.2021.12.022  0.649
2021 Yang F, Guo L, Li Y, Wang G, Wang J, Zhang C, Fang GX, Chen X, Liu L, Yan X, Liu Q, Qu C, Xu Y, Xiao P, Zhu Z, ... ... Sun JP, et al. Structure, function and pharmacology of human itch receptor complexes. Nature. PMID 34789875 DOI: 10.1038/s41586-021-04077-y  0.574
2021 Qu C, Park JY, Yun MW, He QT, Yang F, Kim K, Ham D, Li RR, Iverson TM, Gurevich VV, Sun JP, Chung KY. Scaffolding mechanism of arrestin-2 in the cRaf/MEK1/ERK signaling cascade. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34507982 DOI: 10.1073/pnas.2026491118  0.392
2021 Lin JY, Yang Z, Yang C, Du JX, Yang F, Cheng J, Pan W, Zhang SJ, Yan X, Wang J, Wang J, Tie L, Yu X, Chen X, Sun JP. An ionic lock and a hydrophobic zipper mediate the coupling between an insect pheromone receptor BmOR3 and downstream effectors. The Journal of Biological Chemistry. 101160. PMID 34480896 DOI: 10.1016/j.jbc.2021.101160  0.434
2021 Zhang H, Chen LN, Yang D, Mao C, Shen Q, Feng W, Shen DD, Dai A, Xie S, Zhou Y, Qin J, Sun JP, Scharf DH, Hou T, Zhou T, et al. Structural insights into ligand recognition and activation of the melanocortin-4 receptor. Cell Research. PMID 34433901 DOI: 10.1038/s41422-021-00552-3  0.369
2021 Han MJ, He QT, Yang M, Chen C, Yao Y, Liu X, Wang Y, Zhu ZL, Zhu KK, Qu C, Yang F, Hu C, Guo X, Zhang D, Chen C, ... Sun JP, et al. Single-molecule FRET and conformational analysis of beta-arrestin-1 through genetic code expansion and a Se-click reaction. Chemical Science. 12: 9114-9123. PMID 34276941 DOI: 10.1039/d1sc02653d  0.357
2021 He QT, Xiao P, Huang SM, Jia YL, Zhu ZL, Lin JY, Yang F, Tao XN, Zhao RJ, Gao FY, Niu XG, Xiao KH, Wang J, Jin C, Sun JP, et al. Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2. Nature Communications. 12: 2396. PMID 33888704 DOI: 10.1038/s41467-021-22731-x  0.817
2021 Qu C, Mao C, Xiao P, Shen Q, Zhong YN, Yang F, Shen DD, Tao X, Zhang H, Yan X, Zhao RJ, He J, Guan Y, Zhang C, Hou G, ... ... Sun JP, et al. Ligand recognition, unconventional activation, and G protein coupling of the prostaglandin E receptor EP2 subtype. Science Advances. 7. PMID 33811074 DOI: 10.1126/sciadv.abf1268  0.587
2021 Xu YF, Chen X, Yang Z, Xiao P, Liu CH, Li KS, Yang XZ, Wang YJ, Zhu ZL, Xu ZG, Zhang S, Wang C, Song YC, Zhao WD, Wang CH, ... ... Sun JP, et al. PTP-MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates. Embo Reports. e52141. PMID 33764618 DOI: 10.15252/embr.202052141  0.775
2021 Xiao P, Yan W, Gou L, Zhong YN, Kong L, Wu C, Wen X, Yuan Y, Cao S, Qu C, Yang X, Yang CC, Xia A, Hu Z, Zhang Q, ... ... Sun JP, et al. Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes. Cell. PMID 33571432 DOI: 10.1016/j.cell.2021.01.028  0.753
2021 Ping YQ, Mao C, Xiao P, Zhao RJ, Jiang Y, Yang Z, An WT, Shen DD, Yang F, Zhang H, Qu C, Shen Q, Tian C, Li ZJ, Li S, ... ... Sun JP, et al. Structures of the glucocorticoid-bound adhesion receptor GPR97-G complex. Nature. PMID 33408414 DOI: 10.1038/s41586-020-03083-w  0.82
2020 Lin JY, Cheng J, Du YQ, Pan W, Zhang Z, Wang J, An J, Yang F, Xu YF, Lin H, An WT, Wang J, Yang Z, Chai RJ, Sha XY, ... ... Sun JP, et al. In vitro expansion of pancreatic islet clusters facilitated by hormones and chemicals. Cell Discovery. 6: 20. PMID 33824290 DOI: 10.1038/s41421-020-0159-x  0.614
2020 Sun Y, Zhang D, Ma ML, Lin H, Song Y, Wang J, Ma C, Yu K, An W, Guo S, He D, Yang Z, Xiao P, Hou G, Yu X, ... Sun JP, et al. Optimization of a peptide ligand for the adhesion GPCR ADGRG2 provides a potent tool to explore receptor biology. The Journal of Biological Chemistry. PMID 33303626 DOI: 10.1074/jbc.RA120.014726  0.78
2020 Liu Q, He QT, Lyu X, Yang F, Zhu ZL, Xiao P, Yang Z, Zhang F, Yang ZY, Wang XY, Sun P, Wang QW, Qu CX, Gong Z, Lin JY, ... ... Sun JP, et al. DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl H-NMR probe. Nature Communications. 11: 4857. PMID 32978402 DOI: 10.1038/s41467-020-18433-5  0.823
2020 Zhang D, Wang Y, Lin H, Sun Y, Wang M, Jia Y, Yu X, Jiang H, Xu W, Sun J, Xu Z. Function and therapeutic potential of GPCRs in epididymis. British Journal of Pharmacology. PMID 32901914 DOI: 10.1111/Bph.15252  0.706
2020 Yang F, Mao C, Guo L, Lin J, Ming Q, Xiao P, Wu X, Shen Q, Guo S, Shen DD, Lu R, Zhang L, Huang S, Ping Y, Zhang C, ... ... Sun JP, et al. Structural basis of GPBAR activation and bile acid recognition. Nature. PMID 32698187 DOI: 10.1038/S41586-020-2569-1  0.804
2020 Huang S, Xiao P, Sun J. Structural basis of signaling of cannabinoids receptors: paving a way for rational drug design in controling mutiple neurological and immune diseases. Signal Transduction and Targeted Therapy. 5: 127. PMID 32694501 DOI: 10.1038/S41392-020-00240-5  0.787
2020 Lin JY, Cheng J, Du YQ, Pan W, Zhang Z, Wang J, An J, Yang F, Xu YF, Lin H, An WT, Wang J, Yang Z, Chai RJ, Sha XY, ... ... Sun JP, et al. In vitro expansion of pancreatic islet clusters facilitated by hormones and chemicals. Cell Discovery. 6: 20. PMID 32284878 DOI: 10.1038/S41421-020-0159-X  0.758
2020 Zhao S, Guo S, Yang C, Gong Z, Wang Y, Jia Y, Jiang X, Xu L, Shi L, Yu X, Sun J, Zhang Y, Chen X. Cell active and functionally-relevant small-molecule agonists of calcitonin receptor. Bioorganic Chemistry. 96: 103596. PMID 32004895 DOI: 10.1016/J.Bioorg.2020.103596  0.421
2019 Gong Q, Qin W, Xiao P, Wu X, Li L, Zhang G, Zhang R, Sun J, Yao SQ, Huang W. Internal standard fluorogenic probe based on vibration-induced emission for visualizing PTP1B in living cells. Chemical Communications (Cambridge, England). PMID 31690925 DOI: 10.1039/C9Cc07680H  0.432
2019 Huang SM, Yang F, Cai BY, He QT, Liu Q, Qu CX, Han MJ, Kong W, Jia YL, Li F, Yu X, Sun JP, Wang J. A Genetically Encoded Fluorescent Amino Acid for Monitoring Protein Interactions through FRET. Analytical Chemistry. PMID 31670502 DOI: 10.1021/Acs.Analchem.9B03305  0.797
2019 Park JY, Qu CX, Li RR, Yang F, Yu X, Tian ZM, Shen YM, Cai BY, Yun Y, Sun JP, Chung KY. Structural Mechanism of the Arrestin-3/JNK3 Interaction. Structure (London, England : 1993). PMID 31080119 DOI: 10.1016/J.Str.2019.04.002  0.503
2019 Li K, Hou X, Li R, Bi W, Yang F, Chen X, Xiao P, Liu T, Lu T, Zhou Y, Tian Z, Shen Y, Zhang Y, Wang J, Fang H, ... Sun J, et al. Identification and structure-function analyses of an allosteric inhibitor of the tyrosine phosphatase PTPN22. The Journal of Biological Chemistry. PMID 30979725 DOI: 10.1074/Jbc.Ra118.007129  0.552
2018 Rostaminasab Dolatabad M, Guo LL, Xiao P, Zhu Z, He QT, Yang DX, Qu CX, Guo SC, Fu XL, Li RR, Ge L, Hu KJ, Hong-da L, Shen YM, Yu X, ... Sun JP, et al. Crystal structure and catalytic activity of the PPM1K N94K mutant. Journal of Neurochemistry. PMID 30451284 DOI: 10.1111/Jnc.14631  0.485
2018 Hou X, Rooklin DW, Yang D, Liang X, Li K, Lu J, Wang C, Xiao P, Zhang Y, Sun JP, Fang H. Computational strategy for bound state structure prediction in structure-based virtual screening: a case study of protein tyrosine phosphatase receptor type O inhibitors. Journal of Chemical Information and Modeling. PMID 30299094 DOI: 10.1021/Acs.Jcim.8B00548  0.463
2018 Yang D, Xiao P, Li Q, Fu X, Pan C, Lu D, Wen S, Xia W, He D, Li H, Fang H, Shen Y, Xu Z, Lin A, Yu X, ... ... Sun J, et al. Allosteric modulation of the catalytic VYD loop in Slingshot by its N-terminal domain underlies both Slingshot autoinhibition and activation. The Journal of Biological Chemistry. PMID 30154244 DOI: 10.1074/Jbc.Ra118.004175  0.511
2018 Yang F, Xiao P, Qu CX, Liu Q, Wang LY, Liu ZX, He QT, Liu C, Xu JY, Li RR, Li MJ, Li Q, Guo XZ, Yang ZY, He DF, ... ... Sun JP, et al. Allosteric mechanisms underlie GPCR signaling to SH3-domain proteins through arrestin. Nat Chem Biol. 14: 876-886. PMID 30120361 DOI: 10.1038/s41589-018-0115-3  0.422
2018 Yang F, Xiao P, Qu CX, Liu Q, Wang LY, Liu ZX, He QT, Liu C, Xu JY, Li RR, Li MJ, Li Q, Guo XZ, Yang ZY, He DF, ... ... Sun JP, et al. Allosteric mechanisms underlie GPCR signaling to SH3-domain proteins through arrestin. Nature Chemical Biology. PMID 30120361 DOI: 10.1038/S41589-018-0115-3  0.654
2018 Li N, Yang Z, Li Q, Yu Z, Chen X, Li JC, Li B, Ning SL, Cui M, Sun JP, Yu X. Ablation of somatostatin cells leads to impaired pancreatic islet function and neonatal death in rodents. Cell Death & Disease. 9: 682. PMID 29880854 DOI: 10.1038/S41419-018-0741-4  0.307
2018 Nair A, Chung HC, Sun T, Tyagi S, Dobrolecki LE, Dominguez-Vidana R, Kurley SJ, Orellana M, Renwick A, Henke DM, Katsonis P, Schmitt E, Chan DW, Li H, Mao S, ... ... Sun J, et al. Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer. Nature Medicine. PMID 29578538 DOI: 10.1038/Nm.4507  0.406
2018 Zhang DL, Sun YJ, Ma ML, Wang YJ, Lin H, Li RR, Liang ZL, Gao Y, Yang Z, He DF, Lin A, Mo H, Lu YJ, Li MJ, Kong W, ... ... Sun JP, et al. Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility. Elife. 7. PMID 29393851 DOI: 10.7554/Elife.33432  0.814
2018 Li T, Yu B, Liu Z, Li J, Ma M, Wang Y, Zhu M, Yin H, Wang X, Fu Y, Yu F, Wang X, Fang X, Sun J, Kong W. Homocysteine directly interacts and activates the angiotensin II type I receptor to aggravate vascular injury. Nature Communications. 9: 11. PMID 29296021 DOI: 10.1038/S41467-017-02401-7  0.383
2018 Zhang D, Sun Y, Ma M, Wang Y, Lin H, Li R, Liang Z, Gao Y, Yang Z, He D, Lin A, Mo H, Lu Y, Li M, Kong W, ... ... Sun J, et al. Author response: Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility Elife. DOI: 10.7554/Elife.33432.051  0.782
2017 Xu H, Li Q, Liu J, Zhu J, Li L, Wang Z, Zhang Y, Sun Y, Sun J, Wang R, Yi F. β-Arrestin-1 deficiency ameliorates renal interstitial fibrosis by blocking Wnt1/β-catenin signaling in mice. Journal of Molecular Medicine (Berlin, Germany). PMID 29116339 DOI: 10.1007/S00109-017-1606-5  0.343
2017 Xiao K, Sun J. Elucidating structural and molecular mechanisms of β-arrestin-biased agonism at GPCRs via MS-based proteomics. Cellular Signalling. PMID 28939107 DOI: 10.1016/J.Cellsig.2017.09.013  0.469
2017 Li H, Yang D, Ning S, Xu Y, Yang F, Yin R, Feng T, Han S, Guo L, Zhang P, Qu W, Guo R, Song C, Xiao P, Zhou C, ... ... Sun JP, et al. Switching of the substrate specificity of protein tyrosine phosphatase N12 by cyclin-dependent kinase 2 phosphorylation orchestrating 2 oncogenic pathways. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28842430 DOI: 10.1096/Fj.201700418R  0.547
2017 Zhang H, Xiao P, Wong YT, Shen W, Chhabra M, Peltier R, Jiang Y, He Y, He J, Tan Y, Xie Y, Ho D, Lam YW, Sun J, Sun H. Construction of an alkaline phosphatase-specific two-photon probe and its imaging application in living cells and tissues. Biomaterials. 140: 220-229. PMID 28662402 DOI: 10.1016/J.Biomaterials.2017.06.032  0.442
2017 Li Q, Cui M, Yang F, Li N, Jiang B, Yu Z, Zhang D, Wang Y, Zhu X, Hu H, Li PS, Ning SL, Wang S, Qi H, Song H, ... ... Sun JP, et al. A cullin 4B-RING E3 ligase complex fine-tunes pancreatic δ cell paracrine interactions. The Journal of Clinical Investigation. PMID 28604389 DOI: 10.1172/Jci91348  0.674
2017 Yang Z, Yang F, Zhang D, Liu Z, Lin A, Liu C, Xiao P, Yu X, Sun JP. Phosphorylation of G protein-coupled receptors: from the barcode hypothesis to the flute model. Molecular Pharmacology. PMID 28246190 DOI: 10.1124/Mol.116.107839  0.797
2017 Cahill TJ, Thomsen AR, Tarrasch JT, Plouffe B, Nguyen AH, Yang F, Huang LY, Kahsai AW, Bassoni DL, Gavino BJ, Lamerdin JE, Triest S, Shukla AK, Berger B, Little J, ... ... Sun JP, et al. Distinct conformations of GPCR-β-arrestin complexes mediate desensitization, signaling, and endocytosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28223524 DOI: 10.1073/Pnas.1701529114  0.818
2017 Liu CH, Gong Z, Liang ZL, Liu ZX, Yang F, Sun YJ, Ma ML, Wang YJ, Ji CR, Wang YH, Wang MJ, Cui FA, Lin A, Zheng WS, He DF, ... ... Sun JP, et al. Arrestin-biased AT1R agonism induces acute catecholamine secretion through TRPC3 coupling. Nature Communications. 8: 14335. PMID 28181498 DOI: 10.1038/Ncomms14335  0.823
2016 Dong JH, Wang YJ, Cui M, Wang XJ, Zheng WS, Ma ML, Yang F, He DF, Hu QX, Zhang DL, Ning SL, Liu CH, Wang C, Wang Y, Li XY, ... ... Sun JP, et al. Adaptive Activation of a Stress Response Pathway Improves Learning and Memory Through Gs and β-Arrestin-1-Regulated Lactate Metabolism. Biological Psychiatry. PMID 27916196 DOI: 10.1016/J.Biopsych.2016.09.025  0.716
2016 Ge L, Li KS, Li MM, Xiao P, Hou XB, Chen X, Liu HD, Lin A, Yu X, Ren GJ, Fang H, Sun JP. Identification of a benzo imidazole thiazole derivative as the specific irreversible inhibitor of protein tyrosine phosphatase. Bioorganic & Medicinal Chemistry Letters. PMID 27554446 DOI: 10.1016/J.Bmcl.2016.08.024  0.503
2016 Li H, Yang F, Liu C, Xiao P, Xu Y, Liang Z, Liu C, Wang H, Wang W, Zheng W, Zhang W, Ma X, He D, Song X, Cui F, ... ... Sun JP, et al. Crystal Structure and Substrate Specificity of PTPN12. Cell Reports. PMID 27134172 DOI: 10.1016/J.Celrep.2016.04.016  0.755
2016 Sun JP, Meng F, Yang XS, Lee AP, Chen M, Zhang B, Yu CM. Prevalence of atrial septal pouch and risk of ischemic stroke. International Journal of Cardiology. 214: 37-40. PMID 27057971 DOI: 10.1016/J.Ijcard.2016.03.119  0.319
2016 Sun J, Zhang D, Wang Y, Lin H, Yu X, Xu Z. The Role of G Protein-coupled Receptors in Cochlear Planar Cell Polarity. The International Journal of Biochemistry & Cell Biology. PMID 26921719 DOI: 10.1016/J.Biocel.2016.02.011  0.725
2016 Yu X, Ning S, Sun J. Biased Signaling of GPCR Regulates Pancreatic Beta Cell Secretion and Survival Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.547  0.412
2015 Li A, Yang D, Zhu M, Tsai KC, Xiao KH, Yu X, Sun J, Du L. Discovery of novel FFA4 (GPR120) receptor agonists with β-arrestin2-biased characteristics. Future Medicinal Chemistry. PMID 26653412 DOI: 10.4155/Fmc.15.160  0.444
2015 Liu Y, Xu M, Fan H, Chen M, Wang J, Zhang L, Meng F, Dong Y, Yu CM, Zhang B, Sun JP. Primary cardiac lymphoma: Two rare cases. International Journal of Cardiology. 203: 763-765. PMID 26590890 DOI: 10.1016/J.Ijcard.2015.11.043  0.331
2015 Li KS, Xiao P, Zhang DL, Hou XB, Ge L, Yang DX, Liu HD, He DF, Chen X, Han KR, Song XY, Yu X, Fang H, Sun JP. Identification of para-Substituted Benzoic Acid Derivatives as Potent Inhibitors of the Protein Phosphatase Slingshot. Chemmedchem. PMID 26553423 DOI: 10.1002/Cmdc.201500454  0.711
2015 Hou X, Li K, Yu X, Sun JP, Fang H. Protein Flexibility in Docking-Based Virtual Screening: Discovery of Novel Lymphoid-Specific Tyrosine Phosphatase Inhibitors Using Multiple Crystal Structures. Journal of Chemical Information and Modeling. PMID 26360643 DOI: 10.1021/Acs.Jcim.5B00344  0.361
2015 Yang F, Yu X, Liu C, Qu CX, Gong Z, Liu HD, Li FH, Wang HM, He DF, Yi F, Song C, Tian CL, Xiao KH, Wang JY, Sun JP. Phospho-selective mechanisms of arrestin conformations and functions revealed by unnatural amino acid incorporation and (19)F-NMR. Nature Communications. 6: 8202. PMID 26347956 DOI: 10.1038/Ncomms9202  0.534
2015 Ning SL, Zheng WS, Su J, Liang N, Li H, Zhang D, Dong JH, Zhang ZK, Cui M, Hu QX, Chen CC, Liu CH, Wang C, Pang Q, Chen Y, ... ... Sun JP, et al. Different downstream signaling of CCKAR regulates distinct functions of CCK in pancreatic β cells. British Journal of Pharmacology. PMID 26248680 DOI: 10.1111/Bph.13271  0.761
2015 Liua HD, Wang WB, Xu ZG, Liu CH, He DF, Du LP, Li MY, Yu X, Sun JP. FFA4 receptor (GPR120):A hot target for the development of anti-diabetic therapies. European Journal of Pharmacology. PMID 26123847 DOI: 10.1016/J.Ejphar.2015.06.028  0.331
2015 Pan C, Tang JY, Xu YF, Xiao P, Liu HD, Wang HA, Wang WB, Meng FG, Yu X, Sun JP. The catalytic role of the M2 metal ion in PP2Cα. Scientific Reports. 5: 8560. PMID 25708299 DOI: 10.1038/Srep08560  0.668
2014 Xiao P, Wang X, Wang HM, Fu XL, Cui FA, Yu X, Wen SS, Bi WX, Sun JP. The second-sphere residue T263 is important for the function and catalytic activity of PTP1B via interaction with the WPD-loop. The International Journal of Biochemistry & Cell Biology. 57: 84-95. PMID 25450460 DOI: 10.1016/J.Biocel.2014.10.004  0.554
2014 Hou X, Li R, Li K, Yu X, Sun JP, Fang H. Fast identification of novel lymphoid tyrosine phosphatase inhibitors using target-ligand interaction-based virtual screening. Journal of Medicinal Chemistry. 57: 9309-22. PMID 25372368 DOI: 10.1021/Jm500692U  0.32
2014 Wang XJ, Zhang DL, Xu ZG, Ma ML, Wang WB, Li LL, Han XL, Huo Y, Yu X, Sun JP. Understanding cadherin EGF LAG seven-pass G-type receptors. Journal of Neurochemistry. 131: 699-711. PMID 25280249 DOI: 10.1111/jnc.12955  0.737
2014 Wang HM, Xu YF, Ning SL, Yang DX, Li Y, Du YJ, Yang F, Zhang Y, Liang N, Yao W, Zhang LL, Gu LC, Gao CJ, Pang Q, Chen YX, ... ... Sun JP, et al. The catalytic region and PEST domain of PTPN18 distinctly regulate the HER2 phosphorylation and ubiquitination barcodes. Cell Research. 24: 1067-90. PMID 25081058 DOI: 10.1038/Cr.2014.99  0.683
2014 Hu QX, Dong JH, Du HB, Zhang DL, Ren HZ, Ma ML, Cai Y, Zhao TC, Yin XL, Yu X, Xue T, Xu ZG, Sun JP. Constitutive Gαi coupling activity of very large G protein-coupled receptor 1 (VLGR1) and its regulation by PDZD7 protein. The Journal of Biological Chemistry. 289: 24215-25. PMID 24962568 DOI: 10.1074/Jbc.M114.549816  0.733
2014 Wang HM, Dong JH, Li Q, Hu Q, Ning SL, Zheng W, Cui M, Chen TS, Xie X, Sun JP, Yu X. A stress response pathway in mice upregulates somatostatin level and transcription in pancreatic delta cells through Gs and β-arrestin 1. Diabetologia. 57: 1899-910. PMID 24947582 DOI: 10.1007/S00125-014-3290-0  0.342
2014 Kahsai AW, Rajagopal S, Sun J, Xiao K. Monitoring protein conformational changes and dynamics using stable-isotope labeling and mass spectrometry. Nature Protocols. 9: 1301-19. PMID 24810039 DOI: 10.1038/Nprot.2014.075  0.721
2014 Strachan RT, Sun JP, Rominger DH, Violin JD, Ahn S, Rojas Bie Thomsen A, Zhu X, Kleist A, Costa T, Lefkowitz RJ. Divergent transducer-specific molecular efficacies generate biased agonism at a G protein-coupled receptor (GPCR). The Journal of Biological Chemistry. 289: 14211-24. PMID 24668815 DOI: 10.1074/Jbc.M114.548131  0.798
2014 Li R, Xie DD, Dong JH, Li H, Li KS, Su J, Chen LZ, Xu YF, Wang HM, Gong Z, Cui GY, Yu X, Wang K, Yao W, Xin T, ... ... Sun JP, et al. Molecular mechanism of ERK dephosphorylation by striatal-enriched protein tyrosine phosphatase. Journal of Neurochemistry. 128: 315-29. PMID 24117863 DOI: 10.1111/Jnc.12463  0.64
2013 Jiang H, Sun J, Xu Q, Liu Y, Wei J, Young CY, Yuan H, Lou H. Marchantin M: a novel inhibitor of proteasome induces autophagic cell death in prostate cancer cells. Cell Death & Disease. 4: e761. PMID 23928700 DOI: 10.1038/Cddis.2013.285  0.364
2013 Pan C, Liu HD, Gong Z, Yu X, Hou XB, Xie DD, Zhu XB, Li HW, Tang JY, Xu YF, Yu JQ, Zhang LY, Fang H, Xiao KH, Chen YG, ... ... Sun JP, et al. Cadmium is a potent inhibitor of PPM phosphatases and targets the M1 binding site. Scientific Reports. 3: 2333. PMID 23903585 DOI: 10.1038/Srep02333  0.647
2013 Li R, Gong Z, Pan C, Xie DD, Tang JY, Cui M, Xu YF, Yao W, Pang Q, Xu ZG, Li MY, Yu X, Sun JP. Metal-dependent protein phosphatase 1A functions as an extracellular signal-regulated kinase phosphatase. The Febs Journal. 280: 2700-11. PMID 23560844 DOI: 10.1111/Febs.12275  0.675
2013 Li F, Shi P, Li J, Yang F, Wang T, Zhang W, Gao F, Ding W, Li D, Li J, Xiong Y, Sun J, Gong W, Tian C, Wang J. A genetically encoded 19F NMR probe for tyrosine phosphorylation. Angewandte Chemie (International Ed. in English). 52: 3958-62. PMID 23450644 DOI: 10.1002/Anie.201300463  0.413
2013 Sun J, Li R, Ren H, Xu A, Yu X, Xu Z. The very large G protein coupled receptor (Vlgr1) in hair cells. Journal of Molecular Neuroscience. 50: 204-214. PMID 23180093 DOI: 10.1007/S12031-012-9911-5  0.427
2012 Liu J, Chen M, Li R, Yang F, Shi X, Zhu L, Wang HM, Yao W, Liu Q, Meng FG, Sun JP, Pang Q, Yu X. Biochemical and functional studies of Lymphoid-specific tyrosine phosphatase (Lyp) variants S201F and R266W Plos One. 7. PMID 22952725 DOI: 10.1371/Journal.Pone.0043631  0.368
2012 Dong JH, Chen X, Cui M, Yu X, Pang Q, Sun JP. β2-adrenergic receptor and astrocyte glucose metabolism. Journal of Molecular Neuroscience : Mn. 48: 456-63. PMID 22399228 DOI: 10.1007/S12031-012-9742-4  0.35
2012 Dou HQ, Xu YF, Sun JP, Shang S, Guo S, Zheng LH, Chen CC, Bruce IC, Yu X, Zhou Z. Thiopental-induced insulin secretion via activation of IP3-sensitive calcium stores in rat pancreatic β-cells. American Journal of Physiology. Cell Physiology. 302: C796-803. PMID 22135216 DOI: 10.1152/Ajpcell.00081.2011  0.612
2012 Xiao K, Sun J, Kim J, Rajagopal S, Zhai B, Villén J, Haas W, Kovacs JJ, Shukla AK, Hara MR, Hernandez M, Lachmann A, Zhao S, Lin Y, Cheng Y, et al. Global phosphorylation analysis of β-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR) (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, 34 (15299-15304) doi:10.1073/pnas.1008461107) Proceedings of the National Academy of Sciences of the United States of America. 109: 13464. DOI: 10.1073/Pnas.1211889109  0.78
2011 Kahsai AW, Xiao K, Rajagopal S, Ahn S, Shukla AK, Sun J, Oas TG, Lefkowitz RJ. Multiple ligand-specific conformations of the β2-adrenergic receptor. Nature Chemical Biology. 7: 692-700. PMID 21857662 DOI: 10.1038/Nchembio.634  0.832
2011 Yu X, Chen M, Zhang S, Yu ZH, Sun JP, Wang L, Liu S, Imasaki T, Takagi Y, Zhang ZY. Substrate specificity of lymphoid-specific tyrosine phosphatase (Lyp) and identification of Src kinase-associated protein of 55 kDa homolog (SKAP-HOM) as a Lyp substrate. The Journal of Biological Chemistry. 286: 30526-34. PMID 21719704 DOI: 10.1074/jbc.M111.254722  0.487
2008 Lefkowitz RJ, Sun JP, Shukla AK. A crystal clear view of the beta2-adrenergic receptor. Nature Biotechnology. 26: 189-91. PMID 18259173 DOI: 10.1038/Nbt0208-189  0.607
2008 Shukla AK, Sun JP, Lefkowitz RJ. Crystallizing thinking about the beta2-adrenergic receptor. Molecular Pharmacology. 73: 1333-8. PMID 18239031 DOI: 10.1124/Mol.108.045849  0.588
2007 Yu X, Sun JP, He Y, Guo X, Liu S, Zhou B, Hudmon A, Zhang ZY. Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases. Proceedings of the National Academy of Sciences of the United States of America. 104: 19767-72. PMID 18056643 DOI: 10.1073/Pnas.0706233104  0.498
2007 Sun JP, Luo Y, Yu X, Wang WQ, Zhou B, Liang F, Zhang ZY. Phosphatase activity, trimerization, and the C-terminal polybasic region are all required for PRL1-mediated cell growth and migration. The Journal of Biological Chemistry. 282: 29043-51. PMID 17656357 DOI: 10.1074/jbc.M703537200  0.469
2007 Liang F, Liang J, Wang WQ, Sun JP, Udho E, Zhang ZY. PRL3 promotes cell invasion and proliferation by down-regulation of Csk leading to Src activation. The Journal of Biological Chemistry. 282: 5413-9. PMID 17192274 DOI: 10.1074/jbc.M608940200  0.454
2006 Liu S, Sun JP, Zhou B, Zhang ZY. Structural basis of docking interactions between ERK2 and MAP kinase phosphatase 3. Proceedings of the National Academy of Sciences of the United States of America. 103: 5326-31. PMID 16567630 DOI: 10.1073/pnas.0510506103  0.472
2005 Sun JP, Wang WQ, Yang H, Liu S, Liang F, Fedorov AA, Almo SC, Zhang ZY. Structure and biochemical properties of PRL-1, a phosphatase implicated in cell growth, differentiation, and tumor invasion. Biochemistry. 44: 12009-21. PMID 16142898 DOI: 10.1021/Bi0509191  0.457
2003 Sun JP, Wu L, Fedorov AA, Almo SC, Zhang ZY. Crystal structure of the Yersinia protein-tyrosine phosphatase YopH complexed with a specific small molecule inhibitor Journal of Biological Chemistry. 278: 33392-33399. PMID 12810712 DOI: 10.1074/Jbc.M304693200  0.468
2003 Wang WQ, Sun JP, Zhang ZY. An overview of the protein tyrosine phosphatase superfamily. Current Topics in Medicinal Chemistry. 3: 739-48. PMID 12678841 DOI: 10.2174/1568026033452302  0.492
2003 Sun JP, Fedorov AA, Lee SY, Guo XL, Shen K, Lawrence DS, Almo SC, Zhang ZY. Crystal structure of PTP1B complexed with a potent and selective bidentate inhibitor. The Journal of Biological Chemistry. 278: 12406-14. PMID 12547827 DOI: 10.1074/Jbc.M212491200  0.48
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