Mounia Azzi - Related publications

Affiliations: 
Biochemistry and Molecular Medicine Université de Montréal, Montréal, Canada 
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Heyder NA, Kleinau G, Speck D, Schmidt A, Paisdzior S, Szczepek M, Bauer B, Koch A, Gallandi M, Kwiatkowski D, Bürger J, Mielke T, Beck-Sickinger AG, Hildebrand PW, Spahn CMT, et al. Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-α-MSH and setmelanotide. Cell Research. PMID 34561620 DOI: 10.1038/s41422-021-00569-8   
2021 van Aalst E, Wylie BJ. Cholesterol Is a Dose-Dependent Positive Allosteric Modulator of CCR3 Ligand Affinity and G Protein Coupling. Frontiers in Molecular Biosciences. 8: 724603. PMID 34490352 DOI: 10.3389/fmolb.2021.724603   
2021 Gonias SL. Plasminogen activator receptor assemblies in cell-signaling, innate immunity, and inflammation. American Journal of Physiology. Cell Physiology. PMID 34406905 DOI: 10.1152/ajpcell.00269.2021   
2021 Turu G, Soltész-Katona E, Tóth AD, Juhász C, Cserző M, Misák Á, Balla A, Caron MG, Hunyady L. Biased Coupling to β-Arrestin of Two Common Variants of the CB Cannabinoid Receptor. Frontiers in Endocrinology. 12: 714561. PMID 34484125 DOI: 10.3389/fendo.2021.714561   
2021 Nobrega JN, Raymond R, Rajji TK, Pollock BG. A calcium fluorescence assay for quantification of cholinergic receptor activity of clinical drugs in serum - comparison with radioactive methods. Journal of Pharmacological and Toxicological Methods. 107118. PMID 34481920 DOI: 10.1016/j.vascn.2021.107118   
2021 Leo LM, Abood ME. CB1 Cannabinoid Receptor Signaling and Biased Signaling. Molecules (Basel, Switzerland). 26. PMID 34500853 DOI: 10.3390/molecules26175413   
2021 Mitra A, Sarkar A, Borics A. Universal Properties and Specificities of the β-Adrenergic Receptor-G Protein Complex Activation Mechanism Revealed by All-Atom Molecular Dynamics Simulations. International Journal of Molecular Sciences. 22. PMID 34638767 DOI: 10.3390/ijms221910423   
2021 Sonavane PR, Willert K. Controlling Wnt Signaling Specificity and Implications for Targeting WNTs Pharmacologically. Handbook of Experimental Pharmacology. PMID 34463853 DOI: 10.1007/164_2021_529   
2021 Stahl EL, Bohn LM. Low Intrinsic Efficacy Alone Cannot Explain the Improved Side Effect Profiles of New Opioid Agonists. Biochemistry. PMID 34468132 DOI: 10.1021/acs.biochem.1c00466   
2021 Eguchi A, Ueki A, Hoshiyama J, Kuwata K, Chikaoka Y, Kawamura T, Nagatoishi S, Tsumoto K, Ueki R, Sando S. A DNA Aptamer That Inhibits the Aberrant Signaling of Fibroblast Growth Factor Receptor in Cancer Cells. Jacs Au. 1: 578-585. PMID 34467321 DOI: 10.1021/jacsau.0c00121   
2021 Lin JY, Yang Z, Yang C, Du JX, Yang F, Cheng J, Pan W, Zhang SJ, Yan X, Wang J, Wang J, Tie L, Yu X, Chen X, Sun JP. An ionic lock and a hydrophobic zipper mediate the coupling between an insect pheromone receptor BmOR3 and downstream effectors. The Journal of Biological Chemistry. 101160. PMID 34480896 DOI: 10.1016/j.jbc.2021.101160   
2021 Stepniewski TM, Mancini A, Ågren R, Torrens-Fontanals M, Semache M, Bouvier M, Sahlholm K, Breton B, Selent J. Mechanistic insights into dopaminergic and serotonergic neurotransmission - concerted interactions with helices 5 and 6 drive the functional outcome. Chemical Science. 12: 10990-11003. PMID 34522296 DOI: 10.1039/d1sc00749a   
2021 Smith C, Li A, Krishnamurthy N, Lemmon MA. Phosphatidylserine binding directly regulates TIM-3 function. The Biochemical Journal. PMID 34435619 DOI: 10.1042/BCJ20210425   
2021 Cao AM, Quast RB, Fatemi F, Rondard P, Pin JP, Margeat E. Allosteric modulators enhance agonist efficacy by increasing the residence time of a GPCR in the active state. Nature Communications. 12: 5426. PMID 34521824 DOI: 10.1038/s41467-021-25620-5   
2021 Buwaneka P, Ralko A, Gorai S, Pham H, Cho W. Phosphoinositide binding activity of Smad2 is essential for its function in TGF-β signaling. The Journal of Biological Chemistry. 101303. PMID 34655614 DOI: 10.1016/j.jbc.2021.101303   
2021 Lenglez S, Sablon A, Fénelon G, Boland A, Deleuze JF, Boutoleau-Bretonnière C, Nicolas G, Demoulin JB. Distinct functional classes of PDGFRB pathogenic variants in primary familial brain calcification. Human Molecular Genetics. PMID 34494111 DOI: 10.1093/hmg/ddab258   
2021 Dodat F, Mader S, Lévesque D. Minireview: what is known about SUMOylation among NR4A family members? Journal of Molecular Biology. 167212. PMID 34437889 DOI: 10.1016/j.jmb.2021.167212   
2021 Davidson G. LRPs in WNT Signalling. Handbook of Experimental Pharmacology. PMID 34490514 DOI: 10.1007/164_2021_526   
2021 Kilpatrick LE, Hill SJ. The use of fluorescence correlation spectroscopy to characterise the molecular mobility of G protein-coupled receptors in membrane microdomains: an update. Biochemical Society Transactions. 49: 1547-1554. PMID 34436556 DOI: 10.1042/BST20201001   
2021 Ishida A, Okabe Y, Matsushita T, Sekiguchi T, Nishio T, Komagata T, Iwaki M, Miyata H, Katagi J, Naganawa A, Maruyama T, Imagawa A. Design, synthesis, and biological evaluation of novel somatostatin receptor subtype-2 agonists: Optimization for potency and risk mitigation of hERG and phospholipidosis. Bioorganic & Medicinal Chemistry. 49: 116424. PMID 34626901 DOI: 10.1016/j.bmc.2021.116424   
2021 Berthier A, Staels B, Lefebvre P. An optimized protocol with a stepwise approach to identify specific nuclear receptor ligands from cultured mammalian cells. Star Protocols. 2: 100658. PMID 34286290 DOI: 10.1016/j.xpro.2021.100658   
2021 Deganutti G, Atanasio S, Rujan RM, Sexton PM, Wootten D, Reynolds CA. Exploring Ligand Binding to Calcitonin Gene-Related Peptide Receptors. Frontiers in Molecular Biosciences. 8: 720561. PMID 34513925 DOI: 10.3389/fmolb.2021.720561   
2021 Pandey S, Kumari P, Baidya M, Kise R, Cao Y, Dwivedi-Agnihotri H, Banerjee R, Li XX, Cui CS, Lee JD, Kawakami K, Maharana J, Ranjan A, Chaturvedi M, Jhingan GD, et al. Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors. Molecular Cell. PMID 34582793 DOI: 10.1016/j.molcel.2021.09.007   
2021 Kumar R, Grinberg AV, Li H, Kuo TH, Sako D, Krishnan L, Liharska K, Li J, Grenha R, Maguire MC, Briscoe SD, Pearsall RS, Herrin BR, Suragani RNVS, Castonguay R. Functionally diverse heteromeric traps for ligands of the transforming growth factor-β superfamily. Scientific Reports. 11: 18341. PMID 34526551 DOI: 10.1038/s41598-021-97203-9   
2021 Ma S, Chen Y, Dai A, Yin W, Guo J, Yang D, Zhou F, Jiang Y, Wang MW, Xu HE. Structural mechanism of calcium-mediated hormone recognition and Gβ interaction by the human melanocortin-1 receptor. Cell Research. PMID 34453129 DOI: 10.1038/s41422-021-00557-y   
2021 Cevheroğlu O, Murat M, Mingu-Akmete S, Son ÇD. Ste2p Under the Microscope: the Investigation of Oligomeric States of a Yeast G Protein-Coupled Receptor. The Journal of Physical Chemistry. B. 125: 9526-9536. PMID 34433281 DOI: 10.1021/acs.jpcb.1c05872   
2021 Yuan Y, Jia G, Wu C, Wang W, Cheng L, Li Q, Li Z, Luo K, Yang S, Yan W, Su Z, Shao Z. Structures of signaling complexes of lipid receptors S1PR1 and S1PR5 reveal mechanisms of activation and drug recognition. Cell Research. PMID 34526663 DOI: 10.1038/s41422-021-00566-x   
2021 Tasma Z, Siow A, Harris PWR, Brimble MA, Hay DL, Walker CS. Characterisation of agonist signalling profiles and agonist-dependent antagonism at PACAP-responsive receptors: implications for drug discovery. British Journal of Pharmacology. PMID 34612509 DOI: 10.1111/bph.15700   
2021 Harvey RD, Clancy CE. Mechanisms of cAMP compartmentation in cardiac myocytes: Experimental and computational approaches to understanding. The Journal of Physiology. PMID 34510451 DOI: 10.1113/JP280801   
2021 Mustafá ER, Cordisco González S, Damian M, Cantel S, Denoyelle S, Wagner R, Schiöth HB, Fehrentz JA, Banères JL, Perelló M, Raingo J. LEAP2 Impairs the Capability of the Growth Hormone Secretagogue Receptor to Regulate the Dopamine 2 Receptor Signaling. Frontiers in Pharmacology. 12: 712437. PMID 34447311 DOI: 10.3389/fphar.2021.712437   
2021 Kozielewicz P, Schihada H, Schulte G. Employing Genetically Encoded, Biophysical Sensors to Understand WNT/Frizzled Interaction and Receptor Complex Activation. Handbook of Experimental Pharmacology. PMID 34463848 DOI: 10.1007/164_2021_534   
2021 Castillo G, Kleene R, Schachner M, Loers G, Torda AE. Proteins Binding to the Carbohydrate HNK-1: Common Origins? International Journal of Molecular Sciences. 22. PMID 34360882 DOI: 10.3390/ijms22158116   
2021 Sánchez-Melgar A, Muñoz-López S, Albasanz JL, Martín M. Antitumoral Action of Resveratrol Through Adenosinergic Signaling in C6 Glioma Cells. Frontiers in Neuroscience. 15: 702817. PMID 34539333 DOI: 10.3389/fnins.2021.702817   
2021 Liu T, Yi TL, Yang DQ, Tao YX. Regulation of melanocortin-5 receptor pharmacology by two isoforms of MRAP2 in ricefield eel (Monopterus albus). General and Comparative Endocrinology. 113928. PMID 34653433 DOI: 10.1016/j.ygcen.2021.113928   
2021 McCullock TW, Kammermeier PJ. The evidence for and consequences of metabotropic glutamate receptor heterodimerization. Neuropharmacology. 108801. PMID 34547332 DOI: 10.1016/j.neuropharm.2021.108801   
2021 Pruitt RN, Locci F, Wanke F, Zhang L, Saile SC, Joe A, Karelina D, Hua C, Fröhlich K, Wan WL, Hu M, Rao S, Stolze SC, Harzen A, Gust AA, et al. The EDS1-PAD4-ADR1 node mediates Arabidopsis pattern-triggered immunity. Nature. PMID 34497423 DOI: 10.1038/s41586-021-03829-0   
2021 Faúndez-Parraguez M, Alarcón-Miranda C, Cho YH, Pessoa-Mahana H, Gallardo-Garrido C, Chung H, Faúndez M, Pessoa-Mahana D. New Pyridone-Based Derivatives as Cannabinoid Receptor Type 2 Agonists. International Journal of Molecular Sciences. 22. PMID 34681877 DOI: 10.3390/ijms222011212   
2021 Chen LY, You Q, Lv DZ, Li SH, Zhang SY. GPCR-mediated EGFR transactivation ameliorates skin toxicities induced by afatinib. Acta Pharmacologica Sinica. PMID 34552215 DOI: 10.1038/s41401-021-00774-6   
2021 Kong X, Li ZX, Gao YQ, Liu FH, Chen ZZ, Tian HG, Liu TX, Xu YY, Kang ZW. Genome-Wide Identification of Neuropeptides and Their Receptors in an Aphid Endoparasitoid Wasp, . Insects. 12. PMID 34442310 DOI: 10.3390/insects12080745   
2021 Wang Y, Adegawa S, Miyamoto K, Takasu Y, Iizuka T, Wada S, Mang D, Li X, Kim S, Sato R, Watanabe K. ATP-binding cassette transporter subfamily C members 2, 3 and cadherin protein are susceptibility-determining factors in Bombyx mori for multiple Bacillus thuringiensis Cry1 toxins. Insect Biochemistry and Molecular Biology. 103649. PMID 34560243 DOI: 10.1016/j.ibmb.2021.103649   
2021 Ben David A, Barnea A, Diamant E, Dor E, Schwartz A, Torgeman A, Zichel R. Small Molecule Receptor Binding Inhibitors with In Vivo Efficacy against Botulinum Neurotoxin Serotypes A and E. International Journal of Molecular Sciences. 22. PMID 34445283 DOI: 10.3390/ijms22168577   
2021 Hegron A, Huh E, Deupi X, Sokrat B, Gao W, Le Gouill C, Canouil M, Boissel M, Charpentier G, Roussel R, Balkau B, Froguel P, Plouffe B, Bonnefond A, Lichtarge O, et al. Identification of Key Regions Mediating Human Melatonin Type 1 Receptor Functional Selectivity Revealed by Natural Variants. Acs Pharmacology & Translational Science. 4: 1614-1627. PMID 34661078 DOI: 10.1021/acsptsci.1c00157   
2021 Li Y, Lee H, Heo WD, Zi Z. Revisiting the Role of TGFβ Receptor Internalization for Smad Signaling: It is Not Required in Optogenetic TGFβ Signaling Systems. Advanced Biology. e2101008. PMID 34463435 DOI: 10.1002/adbi.202101008   
2021 Budzinski J, Maschauer S, Kobayashi H, Couvineau P, Vogt H, Gmeiner P, Roggenhofer A, Prante O, Bouvier M, Weikert D. Bivalent ligands promote endosomal trafficking of the dopamine D3 receptor-neurotensin receptor 1 heterodimer. Communications Biology. 4: 1062. PMID 34508168 DOI: 10.1038/s42003-021-02574-4   
2021 Bachurin SO, Makhaeva GF, Shevtsova EF, Aksinenko AY, Grigoriev VV, Shevtsov PN, Goreva TV, Epishina TA, Kovaleva NV, Pushkareva EA, Boltneva NP, Lushchekina SV, Gabrelyan AV, Zamoyski VL, Dubova LG, et al. Conjugation of Aminoadamantane and γ-Carboline Pharmacophores Gives Rise to Unexpected Properties of Multifunctional Ligands. Molecules (Basel, Switzerland). 26. PMID 34576998 DOI: 10.3390/molecules26185527   
2021 Busch L, Vieten S, Brödel S, Endres K, Bufe B. Emerging contributions of formyl peptide receptors to neurodegenerative diseases. Biological Chemistry. PMID 34505459 DOI: 10.1515/hsz-2021-0258   
2021 Xie S, Jiang X, Doycheva DM, Shi H, Jin P, Gao L, Liu R, Xiao J, Hu X, Tang J, Zhang L, Zhang JH. Activation of GPR39 with TC-G 1008 attenuates neuroinflammation via SIRT1/PGC-1α/Nrf2 pathway post-neonatal hypoxic-ischemic injury in rats. Journal of Neuroinflammation. 18: 226. PMID 34645465 DOI: 10.1186/s12974-021-02289-7   
2021 Yang S, Gong Z, Liu Z, Wei M, Xue L, Vlantis AC, Zhang Y, Chan JY, van Hasselt CA, Zeng X, Qiu S, Tang N, Du J, Wei W, Tong MC, et al. Differential Effects of Estrogen Receptor Alpha and Beta on Endogenous Ligands of Peroxisome Proliferator-Activated Receptor Gamma in Papillary Thyroid Cancer. Frontiers in Endocrinology. 12: 708248. PMID 34557159 DOI: 10.3389/fendo.2021.708248   
2021 Ren X, Gelinas AD, Linehan M, Iwasaki A, Wang W, Janjic N, Marie Pyle A. Title: Evolving a RIG-I antagonist: a modified DNA aptamer mimics viral RNA. Journal of Molecular Biology. 167227. PMID 34487794 DOI: 10.1016/j.jmb.2021.167227   
2021 Boritzki V, Hübner H, Allikalt A, Gmeiner P, Wöhrl BM. Optimizing the Expression of Human Dopamine Receptors in . International Journal of Molecular Sciences. 22. PMID 34445358 DOI: 10.3390/ijms22168647