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Billy Breton - Publications

Affiliations: 
Biochemistry and Molecular Medicine Université de Montréal, Montréal, Canada 
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Wright SC, Avet C, Gaitonde SA, Muneta-Arrate I, Le Gouill C, Hogue M, Breton B, Koutsilieri S, Diez-Alarcia R, Héroux M, Lauschke VM, Bouvier M. Conformation- and activation-based BRET sensors differentially report on GPCR-G protein coupling. Science Signaling. 17: eadi4747. PMID 38889226 DOI: 10.1126/scisignal.adi4747  0.794
2024 Gross F, Mancini A, Breton B, Kobayashi H, Pereira PHS, Le Gouill C, Bouvier M, Schann S, Leroy X, Sabbagh L. EGFR signaling and pharmacology in oncology revealed with innovative BRET-based biosensors. Communications Biology. 7: 250. PMID 38429428 DOI: 10.1038/s42003-024-05965-5  0.528
2022 Heydenreich FM, Plouffe B, Rizk A, Milic D, Zhou J, Breton B, Le Gouill C, Inoue A, Bouvier M, Veprintsev D. . Molecular Pharmacology. PMID 35779859 DOI: 10.1124/molpharm.122.000497  0.788
2022 Normand C, Breton B, Salze M, Barbeau E, Mancini A, Audet M. A systematic analysis of prostaglandin E type 3 receptor isoform signaling reveals isoform- and species-dependent L798106 Gα-biased agonist responses. European Journal of Pharmacology. 927: 175043. PMID 35598847 DOI: 10.1016/j.ejphar.2022.175043  0.682
2022 Avet C, Mancini A, Breton B, Le Gouill C, Hauser AS, Normand C, Kobayashi H, Gross F, Hogue M, Lukasheva V, St-Onge S, Carrier M, Héroux M, Morissette S, Fauman EB, et al. Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs. Elife. 11. PMID 35302493 DOI: 10.7554/eLife.74101  0.796
2021 Stepniewski TM, Mancini A, Ågren R, Torrens-Fontanals M, Semache M, Bouvier M, Sahlholm K, Breton B, Selent J. Mechanistic insights into dopaminergic and serotonergic neurotransmission - concerted interactions with helices 5 and 6 drive the functional outcome. Chemical Science. 12: 10990-11003. PMID 34522296 DOI: 10.1039/d1sc00749a  0.816
2021 Trauelsen M, Hiron TK, Lin D, Petersen JE, Breton B, Husted AS, Hjorth SA, Inoue A, Frimurer TM, Bouvier M, O'Callaghan CA, Schwartz TW. Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling. Cell Reports. 35: 109246. PMID 34133934 DOI: 10.1016/j.celrep.2021.109246  0.584
2021 Wright SC, Lukasheva V, Le Gouill C, Kobayashi H, Breton B, Mailhot-Larouche S, Blondel-Tepaz É, Antunes Vieira N, Costa-Neto C, Héroux M, Lambert NA, Parreiras-E-Silva LT, Bouvier M. BRET-based effector membrane translocation assay monitors GPCR-promoted and endocytosis-mediated G activation at early endosomes. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33990469 DOI: 10.1073/pnas.2025846118  0.792
2020 Lukasheva V, Devost D, Le Gouill C, Namkung Y, Martin RD, Longpré JM, Amraei M, Shinjo Y, Hogue M, Lagacé M, Breton B, Aoki J, Tanny JC, Laporte SA, Pineyro G, et al. Signal profiling of the βAR reveals coupling to novel signalling pathways and distinct phenotypic responses mediated by βAR and βAR. Scientific Reports. 10: 8779. PMID 32471984 DOI: 10.1038/S41598-020-65636-3  0.787
2020 Mancini A, Avet C, Breton B, Normand C, Gross F, Lukasheva V, Hogue M, Morissette S, Fauman E, Fortin J, Schann S, Gouill CL, Bouvier M. Profiling the Signaling Repertoire of One Hundred Therapeutically‐Relevant Human GPCRs The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05196  0.777
2018 Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, et al. Publisher Correction: Crystal structure of misoprostol bound to the labor inducer prostaglandin E receptor. Nature Chemical Biology. PMID 30573766 DOI: 10.1038/S41589-018-0214-1  0.512
2018 Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, et al. Crystal structure of misoprostol bound to the labor inducer prostaglandin E receptor. Nature Chemical Biology. PMID 30510194 DOI: 10.1038/S41589-018-0160-Y  0.582
2018 Rives ML, Rady B, Swanson N, Zhao S, Qi J, Arnoult E, Bakaj I, Mancini A, Breton B, Lee PS, Player MR, Pocai A. GPR40-mediated Gα12 activation by allosteric full agonists highly efficacious at potentiating glucose-stimulated insulin secretion in human islets. Molecular Pharmacology. PMID 29572336 DOI: 10.1124/Mol.117.111369  0.443
2018 Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, et al. Crystal structure of EP3 receptor bound to misoprostol-FA Nature Chemical Biology. DOI: 10.2210/Pdb6M9T/Pdb  0.578
2016 Thomsen AR, Plouffe B, Cahill TJ, Shukla AK, Tarrasch JT, Dosey AM, Kahsai AW, Strachan RT, Pani B, Mahoney JP, Huang L, Breton B, Heydenreich FM, Sunahara RK, Skiniotis G, et al. GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling. Cell. PMID 27499021 DOI: 10.1016/J.Cell.2016.07.004  0.83
2014 van der Westhuizen ET, Breton B, Christopoulos A, Bouvier M. Quantification of ligand bias for clinically relevant β2-adrenergic receptor ligands: implications for drug taxonomy. Molecular Pharmacology. 85: 492-509. PMID 24366668 DOI: 10.1124/Mol.113.088880  0.795
2012 Schelshorn D, Joly F, Mutel S, Hampe C, Breton B, Mutel V, Lütjens R. Lateral allosterism in the glucagon receptor family: glucagon-like peptide 1 induces G-protein-coupled receptor heteromer formation. Molecular Pharmacology. 81: 309-18. PMID 22108912 DOI: 10.1124/Mol.111.074757  0.548
2011 Stefan E, Malleshaiah MK, Breton B, Ear PH, Bachmann V, Beyermann M, Bouvier M, Michnick SW. PKA regulatory subunits mediate synergy among conserved G-protein-coupled receptor cascades. Nature Communications. 2: 598. PMID 22186894 DOI: 10.1038/Ncomms1605  0.73
2010 Breton B, Sauvageau É, Zhou J, Bonin H, Le Gouill C, Bouvier M. Multiplexing of multicolor bioluminescence resonance energy transfer. Biophysical Journal. 99: 4037-46. PMID 21156147 DOI: 10.1016/J.Bpj.2010.10.025  0.803
2010 Oner SS, An N, Vural A, Breton B, Bouvier M, Blumer JB, Lanier SM. Regulation of the AGS3·G{alpha}i signaling complex by a seven-transmembrane span receptor. The Journal of Biological Chemistry. 285: 33949-58. PMID 20716524 DOI: 10.1074/Jbc.M110.138073  0.727
2010 Breton B, Lagacé M, Bouvier M. Combining resonance energy transfer methods reveals a complex between the alpha2A-adrenergic receptor, Galphai1beta1gamma2, and GRK2. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 4733-43. PMID 20696855 DOI: 10.1096/fj.10.164061  0.706
2010 Oner SS, Maher EM, Breton B, Bouvier M, Blumer JB. Receptor-regulated interaction of activator of G-protein signaling-4 and Galphai. The Journal of Biological Chemistry. 285: 20588-94. PMID 20452976 DOI: 10.1074/Jbc.C109.088070  0.749
2010 Martel C, Dugré-Brisson S, Boulay K, Breton B, Lapointe G, Armando S, Trépanier V, Duchaîne T, Bouvier M, Desgroseillers L. Multimerization of Staufen1 in live cells. Rna (New York, N.Y.). 16: 585-97. PMID 20075165 DOI: 10.1261/Rna.1664210  0.765
2010 Bockenhauer D, Carpentier E, Rochdi D, van't Hoff W, Breton B, Bernier V, Bouvier M, Bichet DG. Vasopressin type 2 receptor V88M mutation: molecular basis of partial and complete nephrogenic diabetes insipidus. Nephron. Physiology. 114: p1-10. PMID 19816050 DOI: 10.1159/000245059  0.729
2009 Leduc M, Breton B, Galés C, Le Gouill C, Bouvier M, Chemtob S, Heveker N. Functional selectivity of natural and synthetic prostaglandin EP4 receptor ligands. The Journal of Pharmacology and Experimental Therapeutics. 331: 297-307. PMID 19584306 DOI: 10.1124/Jpet.109.156398  0.634
2007 Hamdan FF, Rochdi MD, Breton B, Fessart D, Michaud DE, Charest PG, Laporte SA, Bouvier M. Unraveling G protein-coupled receptor endocytosis pathways using real-time monitoring of agonist-promoted interaction between beta-arrestins and AP-2. The Journal of Biological Chemistry. 282: 29089-100. PMID 17675294 DOI: 10.1074/Jbc.M700577200  0.773
2007 Héroux M, Breton B, Hogue M, Bouvier M. Assembly and signaling of CRLR and RAMP1 complexes assessed by BRET. Biochemistry. 46: 7022-33. PMID 17503773 DOI: 10.1021/Bi0622470  0.694
2006 Hamdan FF, Percherancier Y, Breton B, Bouvier M. Monitoring protein-protein interactions in living cells by bioluminescence resonance energy transfer (BRET). Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 5.23. PMID 18428639 DOI: 10.1002/0471142301.Ns0523S34  0.81
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