| Year |
Citation |
Score |
| 2024 |
Tummino TA, Iliopoulos-Tsoutsouvas C, Braz JM, O'Brien ES, Stein RM, Craik V, Tran NK, Ganapathy S, Liu F, Shiimura Y, Tong F, Ho TC, Radchenko DS, Moroz YS, Rosado SR, ... ... Semache M, et al. Large library docking for cannabinoid-1 receptor agonists with reduced side effects. Biorxiv : the Preprint Server For Biology. PMID 38328157 DOI: 10.1101/2023.02.27.530254 |
0.312 |
|
| 2021 |
Ehrlich AT, Semache M, Couvineau P, Wojcik S, Kobayashi H, Thelen M, Gross F, Hogue M, Le Gouill C, Darcq E, Bouvier M, Kieffer BL. Ackr3-Venus knock-in mouse lights up brain vasculature. Molecular Brain. 14: 151. PMID 34583741 DOI: 10.1186/s13041-021-00862-y |
0.648 |
|
| 2021 |
Stepniewski TM, Mancini A, Ågren R, Torrens-Fontanals M, Semache M, Bouvier M, Sahlholm K, Breton B, Selent J. Mechanistic insights into dopaminergic and serotonergic neurotransmission - concerted interactions with helices 5 and 6 drive the functional outcome. Chemical Science. 12: 10990-11003. PMID 34522296 DOI: 10.1039/d1sc00749a |
0.647 |
|
| 2020 |
Avet C, Sturino C, Grastilleur S, Gouill CL, Semache M, Gross F, Gendron L, Bennani Y, Mancini JA, Sayegh CE, Bouvier M. The PAR2 inhibitor I-287 selectively targets Gα and Gα signaling and has anti-inflammatory effects. Communications Biology. 3: 719. PMID 33247181 DOI: 10.1038/s42003-020-01453-8 |
0.586 |
|
| 2019 |
Ehrlich AT, Semache M, Gross F, Da Fonte DF, Runtz L, Colley C, Mezni A, Le Gouill C, Lukasheva V, Hogue M, Darcq E, Bouvier M, Kieffer BL. Biased Signaling of the Mu Opioid Receptor Revealed in Native Neurons. Iscience. 14: 47-57. PMID 30925410 DOI: 10.1016/J.Isci.2019.03.011 |
0.558 |
|
| 2017 |
Ehrlich AT, Semache M, Bailly J, Wojcik S, Arefin TM, Colley C, Le Gouill C, Gross F, Lukasheva V, Hogue M, Darcq E, Harsan LA, Bouvier M, Kieffer BL. Mapping GPR88-Venus illuminates a novel role for GPR88 in sensory processing. Brain Structure & Function. PMID 29110094 DOI: 10.1007/S00429-017-1547-3 |
0.522 |
|
| 2014 |
Semache M, Ghislain J, Zarrouki B, Tremblay C, Poitout V. Pancreatic and duodenal homeobox-1 nuclear localization is regulated by glucose in dispersed rat islets but not in insulin-secreting cell lines. Islets. 6: e982376. PMID 25437380 DOI: 10.4161/19382014.2014.982376 |
0.329 |
|
| 2013 |
Semache M, Zarrouki B, Fontés G, Fogarty S, Kikani C, Chawki MB, Rutter J, Poitout V. Per-Arnt-Sim kinase regulates pancreatic duodenal homeobox-1 protein stability via phosphorylation of glycogen synthase kinase 3β in pancreatic β-cells. The Journal of Biological Chemistry. 288: 24825-33. PMID 23853095 DOI: 10.1074/Jbc.M113.495945 |
0.322 |
|
| 2012 |
Amyot J, Semache M, Ferdaoussi M, Fontés G, Poitout V. Lipopolysaccharides impair insulin gene expression in isolated islets of Langerhans via Toll-Like Receptor-4 and NF-κB signalling. Plos One. 7: e36200. PMID 22558381 DOI: 10.1371/Journal.Pone.0036200 |
0.408 |
|
| 2011 |
Semplici F, Vaxillaire M, Fogarty S, Semache M, Bonnefond A, Fontés G, Philippe J, Meur G, Diraison F, Sessions RB, Rutter J, Poitout V, Froguel P, Rutter GA. Human mutation within Per-Arnt-Sim (PAS) domain-containing protein kinase (PASK) causes basal insulin hypersecretion. The Journal of Biological Chemistry. 286: 44005-14. PMID 22065581 DOI: 10.1074/Jbc.M111.254995 |
0.31 |
|
| 2010 |
Fontés G, Hagman DK, Latour MG, Semache M, Poitout V. Lack of preservation of insulin gene expression by a glucagon-like peptide 1 agonist or a dipeptidyl peptidase 4 inhibitor in an in vivo model of glucolipotoxicity. Diabetes Research and Clinical Practice. 87: 322-8. PMID 20092903 DOI: 10.1016/J.Diabres.2009.12.020 |
0.329 |
|
| 2010 |
Poitout V, Amyot J, Semache M, Zarrouki B, Hagman D, Fontés G. Glucolipotoxicity of the pancreatic beta cell. Biochimica Et Biophysica Acta. 1801: 289-98. PMID 19715772 DOI: 10.1016/S0003-4266(04)95628-4 |
0.34 |
|
| 2009 |
Fontés G, Semache M, Hagman DK, Tremblay C, Shah R, Rhodes CJ, Rutter J, Poitout V. Involvement of Per-Arnt-Sim Kinase and extracellular-regulated kinases-1/2 in palmitate inhibition of insulin gene expression in pancreatic beta-cells. Diabetes. 58: 2048-58. PMID 19502418 DOI: 10.2337/Db08-0579 |
0.356 |
|
| 2008 |
Wang S, Soni KG, Semache M, Casavant S, Fortier M, Pan L, Mitchell GA. Lipolysis and the integrated physiology of lipid energy metabolism. Molecular Genetics and Metabolism. 95: 117-26. PMID 18762440 DOI: 10.1016/J.Ymgme.2008.06.012 |
0.312 |
|
| 2008 |
Kebede M, Alquier T, Latour MG, Semache M, Tremblay C, Poitout V. The fatty acid receptor GPR40 plays a role in insulin secretion in vivo after high-fat feeding. Diabetes. 57: 2432-7. PMID 18559658 DOI: 10.1016/S1499-2671(08)24147-X |
0.357 |
|
| 2008 |
Hagman DK, Latour MG, Chakrabarti SK, Fontes G, Amyot J, Tremblay C, Semache M, Lausier JA, Roskens V, Mirmira RG, Jetton TL, Poitout V. Cyclical and alternating infusions of glucose and intralipid in rats inhibit insulin gene expression and Pdx-1 binding in islets. Diabetes. 57: 424-31. PMID 17991758 DOI: 10.2337/Db07-1285 |
0.31 |
|
| 2008 |
FontÉs G, Semache M, Hagman D, Rutter J, Poitout V. PAS Kinase Mediates Palmitate Inhibition of Insulin Gene Expression in Pancreatic Beta-Cells Canadian Journal of Diabetes. 32: 303. DOI: 10.1016/S1499-2671(08)24021-9 |
0.328 |
|
| 2004 |
Soni KG, Lehner R, Metalnikov P, O'Donnell P, Semache M, Gao W, Ashman K, Pshezhetsky AV, Mitchell GA. Carboxylesterase 3 (EC 3.1.1.1) is a major adipocyte lipase. The Journal of Biological Chemistry. 279: 40683-9. PMID 15220344 DOI: 10.1074/Jbc.M400541200 |
0.316 |
|
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