| Year |
Citation |
Score |
| 2024 |
Zhang X, Liu G, Zhong YN, Zhang R, Yang CC, Niu C, Pu X, Sun J, Zhang T, Yang L, Zhang C, Li X, Shen X, Xiao P, Sun JP, et al. Structural basis of ligand recognition and activation of the histamine receptor family. Nature Communications. 15: 8296. PMID 39333117 DOI: 10.1038/s41467-024-52585-y |
0.543 |
|
| 2024 |
Shen Q, Tang X, Wen X, Cheng S, Xiao P, Zang SK, Shen DD, Jiang L, Zheng Y, Zhang H, Xu H, Mao C, Zhang M, Hu W, Sun JP, et al. Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2310120. PMID 38647423 DOI: 10.1002/advs.202310120 |
0.501 |
|
| 2024 |
Wang KY, Gao MX, Qi HB, An WT, Lin JY, Ning SL, Yang F, Xiao P, Cheng J, Pan W, Cheng QX, Wang J, Fang L, Sun JP, Yu X. Differential contributions of G protein- or arrestin subtype-mediated signalling underlie urocortin 3-induced somatostatin secretion in pancreatic δ cells. British Journal of Pharmacology. PMID 38613153 DOI: 10.1111/bph.16351 |
0.471 |
|
| 2024 |
Li X, Zhang X, Wen X, Zhang D, Qu C, Miao X, Zhang W, Zhang R, Liu G, Xiao P, Sun JP, Gong W. Structural basis for ligand recognition and activation of the prostanoid receptors. Cell Reports. 43: 113893. PMID 38446662 DOI: 10.1016/j.celrep.2024.113893 |
0.541 |
|
| 2024 |
Mao C, Zhao RJ, Dong YJ, Gao M, Chen LN, Zhang C, Xiao P, Guo J, Qin J, Shen DD, Ji SY, Zang SK, Zhang H, Wang WW, Shen Q, et al. Conformational transitions and activation of the adhesion receptor CD97. Molecular Cell. PMID 38215752 DOI: 10.1016/j.molcel.2023.12.020 |
0.532 |
|
| 2023 |
Yang Z, Wang JY, Yang F, Zhu KK, Wang GP, Guan Y, Ning SL, Lu Y, Li Y, Zhang C, Zheng Y, Zhou SH, Wang XW, Wang MW, Xiao P, et al. Structure of GPR101-Gs enables identification of ligands with rejuvenating potential. Nature Chemical Biology. PMID 37945893 DOI: 10.1038/s41589-023-01456-6 |
0.538 |
|
| 2023 |
Huang SM, Xiong MY, Liu L, Mu J, Wang MW, Jia YL, Cai K, Tie L, Zhang C, Cao S, Wen X, Wang JL, Guo SC, Li Y, Qu CX, ... ... Xiao P, et al. Single hormone or synthetic agonist induces G/G coupling selectivity of EP receptors via distinct binding modes and propagating paths. Proceedings of the National Academy of Sciences of the United States of America. 120: e2216329120. PMID 37478163 DOI: 10.1073/pnas.2216329120 |
0.515 |
|
| 2023 |
Pei Y, Wen X, Guo SC, Yang ZS, Zhang R, Xiao P, Sun JP. Structural insight into the selective agonist ST1936 binding of serotonin receptor 5-HT6. Biochemical and Biophysical Research Communications. 671: 327-334. PMID 37327704 DOI: 10.1016/j.bbrc.2023.05.126 |
0.525 |
|
| 2023 |
Mao C, Xiao P, Tao XN, Qin J, He QT, Zhang C, Guo SC, Du YQ, Chen LN, Shen DD, Yang ZS, Zhang HQ, Huang SM, He YH, Cheng J, et al. Unsaturated bond recognition leads to biased signal in a fatty acid receptor. Science (New York, N.Y.). eadd6220. PMID 36862765 DOI: 10.1126/science.add6220 |
0.502 |
|
| 2022 |
Lin H, Xiao P, Bu RQ, Guo S, Yang Z, Yuan D, Zhu ZL, Zhang CX, He QT, Zhang C, Ping YQ, Zhao RJ, Ma CS, Liu CH, Zhang XN, et al. Structures of the ADGRG2-G complex in apo and ligand-bound forms. Nature Chemical Biology. PMID 35982227 DOI: 10.1038/s41589-022-01084-6 |
0.528 |
|
| 2022 |
Du YQ, Sha XY, Cheng J, Wang J, Lin JY, An WT, Pan W, Zhang LJ, Tao XN, Xu Y, Jia YL, Yang Z, Xiao P, Liu M, Sun JP, et al. Endogenous Lipid-GPR120 Signaling Modulates Pancreatic Islet Homeostasis to Different Extents. Diabetes. PMID 35472681 DOI: 10.2337/db21-0794 |
0.446 |
|
| 2022 |
Ping YQ, Xiao P, Yang F, Zhao RJ, Guo SC, Yan X, Wu X, Zhang C, Lu Y, Zhao F, Zhou F, Xi YT, Yin W, Liu FZ, He DF, et al. Structural basis for the tethered peptide activation of adhesion GPCRs. Nature. PMID 35418678 DOI: 10.1038/s41586-022-04619-y |
0.519 |
|
| 2022 |
Xiao P, Guo S, Wen X, He QT, Lin H, Huang SM, Gou L, Zhang C, Yang Z, Zhong YN, Yang CC, Li Y, Gong Z, Tao XN, Yang ZS, et al. Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4. Nature. PMID 35418677 DOI: 10.1038/s41586-022-04590-8 |
0.49 |
|
| 2022 |
An W, Lin H, Ma L, Zhang C, Zheng Y, Cheng Q, Ma C, Wu X, Zhang Z, Zhong Y, Wang M, He D, Yang Z, Du L, Feng S, ... ... Xiao P, et al. Progesterone activates GPR126 to promote breast cancer development via the Gi pathway. Proceedings of the National Academy of Sciences of the United States of America. 119: e2117004119. PMID 35394864 DOI: 10.1073/pnas.2117004119 |
0.461 |
|
| 2022 |
Lu R, Yan X, Fang G, Zhuang Y, Guo L, Zhang C, Wu X, Xiao P, Cao Y, Yang F, Yu X, Sun JP, Zhou JY. A molecular mechanism of UDCA engagement with GPBAR and subsequent G protein interaction revealed by scattered alanine scanning. Biochemical and Biophysical Research Communications. 600: 14-21. PMID 35182970 DOI: 10.1016/j.bbrc.2022.02.030 |
0.509 |
|
| 2021 |
Yang F, Guo L, Li Y, Wang G, Wang J, Zhang C, Fang GX, Chen X, Liu L, Yan X, Liu Q, Qu C, Xu Y, Xiao P, Zhu Z, et al. Structure, function and pharmacology of human itch receptor complexes. Nature. PMID 34789875 DOI: 10.1038/s41586-021-04077-y |
0.548 |
|
| 2021 |
He QT, Xiao P, Huang SM, Jia YL, Zhu ZL, Lin JY, Yang F, Tao XN, Zhao RJ, Gao FY, Niu XG, Xiao KH, Wang J, Jin C, Sun JP, et al. Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2. Nature Communications. 12: 2396. PMID 33888704 DOI: 10.1038/s41467-021-22731-x |
0.526 |
|
| 2021 |
Qu C, Mao C, Xiao P, Shen Q, Zhong YN, Yang F, Shen DD, Tao X, Zhang H, Yan X, Zhao RJ, He J, Guan Y, Zhang C, Hou G, et al. Ligand recognition, unconventional activation, and G protein coupling of the prostaglandin E receptor EP2 subtype. Science Advances. 7. PMID 33811074 DOI: 10.1126/sciadv.abf1268 |
0.55 |
|
| 2021 |
Xu YF, Chen X, Yang Z, Xiao P, Liu CH, Li KS, Yang XZ, Wang YJ, Zhu ZL, Xu ZG, Zhang S, Wang C, Song YC, Zhao WD, Wang CH, et al. PTP-MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates. Embo Reports. e52141. PMID 33764618 DOI: 10.15252/embr.202052141 |
0.494 |
|
| 2021 |
Xiao P, Yan W, Gou L, Zhong YN, Kong L, Wu C, Wen X, Yuan Y, Cao S, Qu C, Yang X, Yang CC, Xia A, Hu Z, Zhang Q, et al. Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes. Cell. PMID 33571432 DOI: 10.1016/j.cell.2021.01.028 |
0.514 |
|
| 2021 |
Ping YQ, Mao C, Xiao P, Zhao RJ, Jiang Y, Yang Z, An WT, Shen DD, Yang F, Zhang H, Qu C, Shen Q, Tian C, Li ZJ, Li S, et al. Structures of the glucocorticoid-bound adhesion receptor GPR97-G complex. Nature. PMID 33408414 DOI: 10.1038/s41586-020-03083-w |
0.544 |
|
| 2020 |
Sun Y, Zhang D, Ma ML, Lin H, Song Y, Wang J, Ma C, Yu K, An W, Guo S, He D, Yang Z, Xiao P, Hou G, Yu X, et al. Optimization of a peptide ligand for the adhesion GPCR ADGRG2 provides a potent tool to explore receptor biology. The Journal of Biological Chemistry. PMID 33303626 DOI: 10.1074/jbc.RA120.014726 |
0.468 |
|
| 2020 |
Liu Q, He QT, Lyu X, Yang F, Zhu ZL, Xiao P, Yang Z, Zhang F, Yang ZY, Wang XY, Sun P, Wang QW, Qu CX, Gong Z, Lin JY, et al. DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl H-NMR probe. Nature Communications. 11: 4857. PMID 32978402 DOI: 10.1038/s41467-020-18433-5 |
0.515 |
|
| 2020 |
Liang X, Fu H, Xiao P, Fang H, Hou X. Design, synthesis and biological evaluation of imidazolidine-2,4-dione and 2-thioxothiazolidin-4-one derivatives as lymphoid-specific tyrosine phosphatase inhibitors. Bioorganic Chemistry. 103: 104124. PMID 32768742 DOI: 10.1016/J.Bioorg.2020.104124 |
0.315 |
|
| 2020 |
Yang F, Mao C, Guo L, Lin J, Ming Q, Xiao P, Wu X, Shen Q, Guo S, Shen DD, Lu R, Zhang L, Huang S, Ping Y, Zhang C, et al. Structural basis of GPBAR activation and bile acid recognition. Nature. PMID 32698187 DOI: 10.1038/S41586-020-2569-1 |
0.562 |
|
| 2020 |
Huang S, Xiao P, Sun J. Structural basis of signaling of cannabinoids receptors: paving a way for rational drug design in controling mutiple neurological and immune diseases. Signal Transduction and Targeted Therapy. 5: 127. PMID 32694501 DOI: 10.1038/S41392-020-00240-5 |
0.451 |
|
| 2019 |
Gong Q, Qin W, Xiao P, Wu X, Li L, Zhang G, Zhang R, Sun J, Yao SQ, Huang W. Internal standard fluorogenic probe based on vibration-induced emission for visualizing PTP1B in living cells. Chemical Communications (Cambridge, England). PMID 31690925 DOI: 10.1039/C9Cc07680H |
0.466 |
|
| 2019 |
Li K, Hou X, Li R, Bi W, Yang F, Chen X, Xiao P, Liu T, Lu T, Zhou Y, Tian Z, Shen Y, Zhang Y, Wang J, Fang H, et al. Identification and structure-function analyses of an allosteric inhibitor of the tyrosine phosphatase PTPN22. The Journal of Biological Chemistry. PMID 30979725 DOI: 10.1074/Jbc.Ra118.007129 |
0.551 |
|
| 2018 |
Rostaminasab Dolatabad M, Guo LL, Xiao P, Zhu Z, He QT, Yang DX, Qu CX, Guo SC, Fu XL, Li RR, Ge L, Hu KJ, Hong-da L, Shen YM, Yu X, et al. Crystal structure and catalytic activity of the PPM1K N94K mutant. Journal of Neurochemistry. PMID 30451284 DOI: 10.1111/Jnc.14631 |
0.518 |
|
| 2018 |
Hou X, Rooklin DW, Yang D, Liang X, Li K, Lu J, Wang C, Xiao P, Zhang Y, Sun JP, Fang H. Computational strategy for bound state structure prediction in structure-based virtual screening: a case study of protein tyrosine phosphatase receptor type O inhibitors. Journal of Chemical Information and Modeling. PMID 30299094 DOI: 10.1021/Acs.Jcim.8B00548 |
0.55 |
|
| 2018 |
Yang D, Xiao P, Li Q, Fu X, Pan C, Lu D, Wen S, Xia W, He D, Li H, Fang H, Shen Y, Xu Z, Lin A, Yu X, et al. Allosteric modulation of the catalytic VYD loop in Slingshot by its N-terminal domain underlies both Slingshot autoinhibition and activation. The Journal of Biological Chemistry. PMID 30154244 DOI: 10.1074/Jbc.Ra118.004175 |
0.543 |
|
| 2018 |
Yang F, Xiao P, Qu CX, Liu Q, Wang LY, Liu ZX, He QT, Liu C, Xu JY, Li RR, Li MJ, Li Q, Guo XZ, Yang ZY, He DF, et al. Allosteric mechanisms underlie GPCR signaling to SH3-domain proteins through arrestin. Nature Chemical Biology. PMID 30120361 DOI: 10.1038/S41589-018-0115-3 |
0.583 |
|
| 2017 |
Li H, Yang D, Ning S, Xu Y, Yang F, Yin R, Feng T, Han S, Guo L, Zhang P, Qu W, Guo R, Song C, Xiao P, Zhou C, et al. Switching of the substrate specificity of protein tyrosine phosphatase N12 by cyclin-dependent kinase 2 phosphorylation orchestrating 2 oncogenic pathways. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28842430 DOI: 10.1096/Fj.201700418R |
0.525 |
|
| 2017 |
Zhang H, Xiao P, Wong YT, Shen W, Chhabra M, Peltier R, Jiang Y, He Y, He J, Tan Y, Xie Y, Ho D, Lam YW, Sun J, Sun H. Construction of an alkaline phosphatase-specific two-photon probe and its imaging application in living cells and tissues. Biomaterials. 140: 220-229. PMID 28662402 DOI: 10.1016/J.Biomaterials.2017.06.032 |
0.488 |
|
| 2017 |
Yang Z, Yang F, Zhang D, Liu Z, Lin A, Liu C, Xiao P, Yu X, Sun JP. Phosphorylation of G protein-coupled receptors: from the barcode hypothesis to the flute model. Molecular Pharmacology. PMID 28246190 DOI: 10.1124/Mol.116.107839 |
0.584 |
|
| 2017 |
Liu CH, Gong Z, Liang ZL, Liu ZX, Yang F, Sun YJ, Ma ML, Wang YJ, Ji CR, Wang YH, Wang MJ, Cui FA, Lin A, Zheng WS, He DF, ... ... Xiao P, et al. Arrestin-biased AT1R agonism induces acute catecholamine secretion through TRPC3 coupling. Nature Communications. 8: 14335. PMID 28181498 DOI: 10.1038/Ncomms14335 |
0.539 |
|
| 2016 |
Ge L, Li KS, Li MM, Xiao P, Hou XB, Chen X, Liu HD, Lin A, Yu X, Ren GJ, Fang H, Sun JP. Identification of a benzo imidazole thiazole derivative as the specific irreversible inhibitor of protein tyrosine phosphatase. Bioorganic & Medicinal Chemistry Letters. PMID 27554446 DOI: 10.1016/J.Bmcl.2016.08.024 |
0.533 |
|
| 2016 |
Li H, Yang F, Liu C, Xiao P, Xu Y, Liang Z, Liu C, Wang H, Wang W, Zheng W, Zhang W, Ma X, He D, Song X, Cui F, et al. Crystal Structure and Substrate Specificity of PTPN12. Cell Reports. PMID 27134172 DOI: 10.1016/J.Celrep.2016.04.016 |
0.533 |
|
| 2015 |
Li KS, Xiao P, Zhang DL, Hou XB, Ge L, Yang DX, Liu HD, He DF, Chen X, Han KR, Song XY, Yu X, Fang H, Sun JP. Identification of para-Substituted Benzoic Acid Derivatives as Potent Inhibitors of the Protein Phosphatase Slingshot. Chemmedchem. PMID 26553423 DOI: 10.1002/Cmdc.201500454 |
0.496 |
|
| 2015 |
Pan C, Tang JY, Xu YF, Xiao P, Liu HD, Wang HA, Wang WB, Meng FG, Yu X, Sun JP. The catalytic role of the M2 metal ion in PP2Cα. Scientific Reports. 5: 8560. PMID 25708299 DOI: 10.1038/Srep08560 |
0.48 |
|
| 2014 |
Xiao P, Wang X, Wang HM, Fu XL, Cui FA, Yu X, Wen SS, Bi WX, Sun JP. The second-sphere residue T263 is important for the function and catalytic activity of PTP1B via interaction with the WPD-loop. The International Journal of Biochemistry & Cell Biology. 57: 84-95. PMID 25450460 DOI: 10.1016/J.Biocel.2014.10.004 |
0.51 |
|
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