Florian Eichler, MD - Publications

Affiliations: 
Neurology Massachusetts General Hospital, Boston, MA 
Area:
ALD, HSAN1, Tay Sachs

22/145 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Zhu J, Eichler F, Biffi A, Duncan CN, Williams DA, Majzoub JA. The Changing Face of Adrenoleukodystrophy. Endocrine Reviews. PMID 32364223 DOI: 10.1210/Endrev/Bnaa013  0.325
2020 Orchard PJ, Eichler F, Duncan C, De Oliveira S, Thrasher AJ, Kühl J, Lund TC, Sevin C, Gissen P, Amartino H, Smith NJ, Shamir E, Chin W, McNeil E, Aubourg P, et al. Lenti-D Hematopoietic Stem Cell Gene Therapy Stabilizes Neurologic Function in Boys with Cerebral Adrenoleukodystrophy Biology of Blood and Marrow Transplantation. 26: S37-S38. DOI: 10.1016/J.Bbmt.2019.12.103  0.301
2019 Huffnagel IC, Laheji FK, Aziz-Bose R, Tritos NA, Marino R, Linthorst GE, Kemp S, Engelen M, Eichler F. The Natural History of Adrenal Insufficiency in X-Linked Adrenoleukodystrophy: An International Collaboration. The Journal of Clinical Endocrinology and Metabolism. 104: 118-126. PMID 30252065 DOI: 10.1210/Jc.2018-01307  0.3
2019 Duncan C, Eichler F, Thrasher AJ, Orchard PJ, De Oliveira SN, Lund TC, Amartino H, Smith NJ, McNeil E, Chin W, Aubourg P, Williams DA. Updated Safety and Efficacy Outcomes from an Ongoing Phase 2/3 Trial of Lenti-D Autologous Hematopoietic Stem Cell Gene Therapy for the Treatment of Cerebral Adrenoleukodystrophy Biology of Blood and Marrow Transplantation. 25: S89-S90. DOI: 10.1016/J.Bbmt.2018.12.169  0.307
2018 Rodan LH, Qi W, Ducker GS, Demirbas D, Laine R, Yang E, Walker MA, Eichler F, Rabinowitz JD, Anselm I, Berry GT. 5,10-methenyltetrahydrofolate synthetase deficiency causes a neurometabolic disorder associated with microcephaly, epilepsy, and cerebral hypomyelination. Molecular Genetics and Metabolism. PMID 30031689 DOI: 10.1016/J.Ymgme.2018.06.006  0.333
2017 Eichler F, Duncan C, Musolino PL, Orchard PJ, De Oliveira S, Thrasher AJ, Armant M, Dansereau C, Lund TC, Miller WP, Raymond GV, Sankar R, Shah AJ, Sevin C, Gaspar HB, et al. Hematopoietic Stem-Cell Gene Therapy for Cerebral Adrenoleukodystrophy. The New England Journal of Medicine. PMID 28976817 DOI: 10.1056/Nejmoa1700554  0.328
2017 Curiel J, Steinberg SJ, Bright S, Snowden A, Moser AB, Eichler F, Dubbs HA, Hacia JG, Ely JJ, Bezner J, Gean A, Vanderver A. X-linked adrenoleukodystrophy in a chimpanzee due to an ABCD1 mutation reported in multiple unrelated humans. Molecular Genetics and Metabolism. PMID 28919002 DOI: 10.1016/J.Ymgme.2017.08.012  0.321
2017 Adang LA, Sherbini O, Ball L, Bloom M, Darbari A, Amartino H, DiVito D, Eichler F, Escolar M, Evans SH, Fatemi A, Fraser J, Hollowell L, Jaffe N, Joseph C, et al. Revised consensus statement on the preventive and symptomatic care of patients with leukodystrophies. Molecular Genetics and Metabolism. PMID 28863857 DOI: 10.1016/J.Ymgme.2017.08.006  0.491
2015 Stockler-Ipsiroglu S, Apatean D, Battini R, DeBrosse S, Dessoffy K, Edvardson S, Eichler F, Johnston K, Koeller DM, Nouioua S, Tazir M, Verma A, Dowling MD, Wierenga KJ, Wierenga AM, et al. Arginine:glycine amidinotransferase (AGAT) deficiency: Clinical features and long term outcomes in 16 patients diagnosed worldwide. Molecular Genetics and Metabolism. PMID 26490222 DOI: 10.1016/J.Ymgme.2015.10.003  0.329
2015 Jun BK, Chandra A, Kuljis D, Schmidt BP, Eichler FS. Substrate Availability of Mutant SPT Alters Neuronal Branching and Growth Cone Dynamics in Dorsal Root Ganglia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 13713-9. PMID 26446223 DOI: 10.1523/Jneurosci.1403-15.2015  0.677
2012 Horvath G, Eichler F, Poskitt K, Stockler-Ipsiroglu S. Failure of repeated cyclophosphamide pulse therapy in childhood cerebral X-linked adrenoleukodystrophy Neuropediatrics. 43: 48-52. PMID 22430161 DOI: 10.1055/S-0032-1307455  0.305
2012 David W, Oaklander AL, Pan J, Novak P, Brown R, Eichler F. Neurophysiology and Intraepidermal Nerve Fiber Density in Hereditary Sensory and Autonomic Neuropathy Type 1 (HSAN1) (P03.202) Neurology. 78. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P03.202  0.303
2011 Garofalo K, Penno A, Schmidt BP, Lee HJ, Frosch MP, von Eckardstein A, Brown RH, Hornemann T, Eichler FS. Oral L-serine supplementation reduces production of neurotoxic deoxysphingolipids in mice and humans with hereditary sensory autonomic neuropathy type 1. The Journal of Clinical Investigation. 121: 4735-45. PMID 22045570 DOI: 10.1172/Jci57549  0.492
2011 Kohlschütter A, Eichler F. Childhood leukodystrophies: a clinical perspective. Expert Review of Neurotherapeutics. 11: 1485-96. PMID 21955203 DOI: 10.1586/Ern.11.135  0.324
2010 Penno A, Reilly MM, Houlden H, Laurá M, Rentsch K, Niederkofler V, Stoeckli ET, Nicholson G, Eichler F, Brown RH, von Eckardstein A, Hornemann T. Hereditary sensory neuropathy type 1 is caused by the accumulation of two neurotoxic sphingolipids. The Journal of Biological Chemistry. 285: 11178-87. PMID 20097765 DOI: 10.1074/Jbc.M109.092973  0.321
2009 Eichler FS, Hornemann T, McCampbell A, Kuljis D, Penno A, Vardeh D, Tamrazian E, Garofalo K, Lee HJ, Kini L, Selig M, Frosch M, Gable K, von Eckardstein A, Woolf CJ, et al. Overexpression of the wild-type SPT1 subunit lowers desoxysphingolipid levels and rescues the phenotype of HSAN1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14646-51. PMID 19923297 DOI: 10.1523/Jneurosci.2536-09.2009  0.667
2008 Eichler F, Aubourg P. Therapeutics of X-linked adrenoleukodystrophy Drug Discovery Today: Therapeutic Strategies. 5: 237-242. DOI: 10.1016/J.Ddstr.2009.04.002  0.3
2007 Eichler F, Mahmood A, Loes D, Bezman L, Lin D, Moser HW, Raymond GV. Magnetic resonance imaging detection of lesion progression in adult patients with X-linked adrenoleukodystrophy. Archives of Neurology. 64: 659-64. PMID 17502464 DOI: 10.1001/Archneur.64.5.659  0.491
2002 Eichler FS, Itoh R, Barker PB, Mori S, Garrett ES, van Zijl PC, Moser HW, Raymond GV, Melhem ER. Proton MR spectroscopic and diffusion tensor brain MR imaging in X-linked adrenoleukodystrophy: initial experience. Radiology. 225: 245-52. PMID 12355012 DOI: 10.1148/Radiol.2251011040  0.42
2002 Eichler FS, Barker PB, Cox C, Edwin D, Ulug AM, Moser HW, Raymond GV. Proton MR spectroscopic imaging predicts lesion progression on MRI in X-linked adrenoleukodystrophy. Neurology. 58: 901-7. PMID 11914405 DOI: 10.1212/Wnl.58.6.901  0.457
2001 Ito R, Melhem ER, Mori S, Eichler FS, Raymond GV, Moser HW. Diffusion tensor brain MR imaging in X-linked cerebral adrenoleukodystrophy. Neurology. 56: 544-7. PMID 11222805 DOI: 10.1212/Wnl.56.4.544  0.404
2001 Ingeholm ML, Levine BA, Eichler F, Tu H, Jimenez-Sanchez G, Moser H. A multi-center clinical trial using next generation internet technology Proceedings of Spie - the International Society For Optical Engineering. 4323: 151-158. DOI: 10.1117/12.435470  0.349
Low-probability matches (unlikely to be authored by this person)
2016 Gong Y, Kok R, Mu D, Gao G, Eichler F. 295. Intrathecal Delivery of rAAV9-ABCD1 by Osmotic Pump in a Mouse Model of Adrenomyeloneuropathy Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33104-5  0.296
2018 Ahrens-Nicklas R, Schlotawa L, Ballabio A, Brunetti-Pierri N, De Castro M, Dierks T, Eichler F, Ficicioglu C, Finglas A, Gaertner J, Kirmse B, Klepper J, Lee M, Olsen A, Parenti G, et al. Complex care of individuals with multiple sulfatase deficiency: Clinical cases and consensus statement. Molecular Genetics and Metabolism. PMID 29397290 DOI: 10.1016/J.Ymgme.2018.01.005  0.296
2006 Eichler F, Tan WH, Shih VE, Grant PE, Krishnamoorthy K. Proton magnetic resonance spectroscopy and diffusion-weighted imaging in isolated sulfite oxidase deficiency. Journal of Child Neurology. 21: 801-5. PMID 16970890 DOI: 10.1177/08830738060210090601  0.29
2008 Ratai E, Kok T, Wiggins C, Wiggins G, Grant E, Gagoski B, O'Neill G, Adalsteinsson E, Eichler F. Seven-Tesla proton magnetic resonance spectroscopic imaging in adult X-linked adrenoleukodystrophy. Archives of Neurology. 65: 1488-94. PMID 19001168 DOI: 10.1001/Archneur.65.11.1488  0.287
2016 Eichler F, Ratai E, Carroll JJ, Masdeu JC. Inherited or acquired metabolic disorders Handbook of Clinical Neurology. 135: 603-636. PMID 27432685 DOI: 10.1016/B978-0-444-53485-9.00029-5  0.285
2015 Helman G, Van Haren K, Bonkowsky JL, Bernard G, Pizzino A, Braverman N, Suhr D, Patterson MC, Ali Fatemi S, Leonard J, van der Knaap MS, Back SA, Damiani S, Goldman SA, Takanohashi A, ... ... Eichler F, et al. Disease specific therapies in leukodystrophies and leukoencephalopathies. Molecular Genetics and Metabolism. 114: 527-36. PMID 25684057 DOI: 10.1016/J.Ymgme.2015.01.014  0.282
2009 Penno A, Eichler F, Hornemann T. Accumulation of two atypical sphingolipids underlies the pathology in hereditary sensory neuropathy HSAN1 Chemistry and Physics of Lipids. 160: S11. DOI: 10.1016/J.Chemphyslip.2009.06.120  0.277
2019 Gantner ML, Eade K, Wallace M, Handzlik MK, Fallon R, Trombley J, Bonelli R, Giles S, Harkins-Perry S, Heeren TFC, Sauer L, Ideguchi Y, Baldini M, Scheppke L, Dorrell MI, ... ... Eichler F, et al. Serine and Lipid Metabolism in Macular Disease and Peripheral Neuropathy. The New England Journal of Medicine. PMID 31509666 DOI: 10.1056/Nejmoa1815111  0.276
2019 Fridman V, Suriyanarayanan S, Novak P, David W, Macklin EA, McKenna-Yasek D, Walsh K, Aziz-Bose R, Oaklander AL, Brown R, Hornemann T, Eichler F. Randomized trial of l-serine in patients with hereditary sensory and autonomic neuropathy type 1. Neurology. PMID 30626650 DOI: 10.1212/Wnl.0000000000006811  0.275
2009 Eichler F, Grodd W, Grant E, Sessa M, Biffi A, Bley A, Kohlschuetter A, Loes DJ, Kraegeloh-Mann I. Metachromatic leukodystrophy: a scoring system for brain MR imaging observations. Ajnr. American Journal of Neuroradiology. 30: 1893-7. PMID 19797797 DOI: 10.3174/Ajnr.A1739  0.275
2012 Yerramilli-Rao P, Giannikopoulos O, Kublis K, Pan J, Eichler F. The Natural History of Late Onset Tay-Sachs Disease (P01.243) Neurology. 78: P01.243-P01.243. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P01.243  0.274
2016 Cox G, Eichler F, Sathe S, Kissell J, Hamed A, Kahn S. Functional performance in patients with late-onset Tay-Sachs and Sandhoff diseases Molecular Genetics and Metabolism. 117: S37. DOI: 10.1016/J.Ymgme.2015.12.228  0.273
2018 Gong Y, Berenson A, Laheji F, Gao G, Wang D, Ng C, Volak A, Kok R, Kreouzis V, Dijkstra I, Kemp S, Maguire CA, Eichler F. Intrathecal Adeno-Associated Virus Vector-mediated Gene Delivery for Adrenomyeloneuropathy. Human Gene Therapy. PMID 30358470 DOI: 10.1089/Hum.2018.079  0.272
2017 Gong Y, Sasidharan N, Laheji F, Frosch M, Musolino P, Tanzi R, Kim DY, Biffi A, El Khoury J, Eichler F. Microglial dysfunction as a key pathologic change in adrenomyeloneuropathy. Annals of Neurology. PMID 29059709 DOI: 10.1002/Ana.25085  0.267
2006 Eichler F, D'Arceuil H, Selig M, Frosch M, Powers J, de Crespigny A. AXONAL ABNORMALITIES IN THE BRAIN OF THE ABCD1 KNOCKOUT MOUSE, AN ANIMAL MODEL OF X-LINKED ADRENOLEUKODYSTROPHY Neuropediatrics. 37. DOI: 10.1055/S-2006-943679  0.266
2009 Han G, Gupta SD, Gable K, Niranjanakumari S, Moitra P, Eichler F, Brown RH, Harmon JM, Dunn TM. Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities. Proceedings of the National Academy of Sciences of the United States of America. 106: 8186-91. PMID 19416851 DOI: 10.1073/Pnas.0811269106  0.265
1999 Ipsiroglu OS, Eichler F, Stöckler-Ipsiroglu S, Trattnig S. Cerebral blood flow velocities in an infant with moyamoya disease Pediatric Neurology. 21: 739-741. PMID 10580888 DOI: 10.1016/S0887-8994(99)00070-3  0.263
2007 Eichler F, Krishnamoorthy K, Grant PE. Magnetic resonance imaging evaluation of possible neonatal sinovenous thrombosis. Pediatric Neurology. 37: 317-23. PMID 17950416 DOI: 10.1016/J.Pediatrneurol.2007.06.018  0.263
2016 Shapiro E, Bernstein J, Adams HR, Barbier AJ, Buracchio T, Como P, Delaney KA, Eichler F, Goldsmith JC, Hogan M, Kovacs S, Mink JW, Odenkirchen J, Parisi MA, Skrinar A, et al. Neurocognitive clinical outcome assessments for inborn errors of metabolism and other rare conditions. Molecular Genetics and Metabolism. PMID 27132782 DOI: 10.1016/J.Ymgme.2016.04.006  0.262
2013 Pan J, Caruso P, Loes D, Kubilus K, Hayden D, Eichler F. Brain MRI abnormalities in GM2-gangliosidosis Molecular Genetics and Metabolism. 108: S71-S72. DOI: 10.1016/J.Ymgme.2012.11.187  0.262
2018 Puga AC, Hamed A, Kissell J, Minini P, Pabla AK, Kahn S, Eichler F, Stephen CD, Tifft CJ, Toro C, Johnston J, Lau HA, Haxton E, Gray-Edwards H, Fischer T. Functional performance in late-onset GM2 gangliosidosis (Tay-Sachs and Sandhoff diseases), longitudinal data over 3 consecutive years Molecular Genetics and Metabolism. 123: S122. DOI: 10.1016/J.Ymgme.2017.12.330  0.262
2016 Amel Karaa A, Haxton E, Yerramilli-Rao P, Giannikopoulos O, Pollak L, Morgan A, Sharma N, Kubilus K, Khan S, Sathe S, Tifft C, Pan J, Eichler F. Retrospective survey of late onset Tay-Sachs disease Molecular Genetics and Metabolism. 117: S64-S65. DOI: 10.1016/J.Ymgme.2015.12.312  0.257
1969 Cherest H, Eichler F, Robichon-Szulmajster H. Genetic and regulatory aspects of methionine biosynthesis in Saccharomyces cerevisiae Journal of Bacteriology. 97: 328-336. PMID 5764336 DOI: 10.1128/Jb.97.1.328-336.1969  0.256
2012 Yerramilli-Rao P, Giannikopoulos O, Kublis K, Pan J, Eichler F. The Natural History of Late Onset Tay-Sachs Disease Molecular Genetics and Metabolism. 105: S67. DOI: 10.1016/J.Ymgme.2011.11.181  0.256
2006 Smith EE, Eichler F. Cerebral amyloid angiopathy and lobar intracerebral hemorrhage. Archives of Neurology. 63: 148-51. PMID 16401753 DOI: 10.1001/Archneur.63.1.148  0.255
2019 Sadjadi R, Sullivan S, Grant N, Thomas SE, Doyle M, Hammond C, Duong R, Corre C, David W, Eichler F. Clinical Myopathy in Patients with Nephropathic Cystinosis. Muscle & Nerve. PMID 31588568 DOI: 10.1002/Mus.26726  0.254
2015 Vanderver A, Prust M, Tonduti D, Mochel F, Hussey HM, Helman G, Garbern J, Eichler F, Labauge P, Aubourg P, Rodriguez D, Patterson MC, Van Hove JL, Schmidt J, Wolf NI, et al. Case definition and classification of leukodystrophies and leukoencephalopathies. Molecular Genetics and Metabolism. 114: 494-500. PMID 25649058 DOI: 10.1016/J.Ymgme.2015.01.006  0.248
2020 Sadjadi R, Sullivan S, Grant N, Thomas SE, Doyle M, Hammond C, Corre C, Mello N, David WS, Eichler F. Clinical Trial Readiness Study of Distal Myopathy and Dysphagia in Nephropathic Cystinosis. Muscle & Nerve. PMID 32737993 DOI: 10.1002/Mus.27039  0.247
1999 Ipsiroglu OS, Eichler F, Stoeckler-Ipsiroglu S. Cerebral Doppler sonography of the neonate. A résumé after 20 years and future aspects. Clinics in Perinatology. 26: 905-946. DOI: 10.1016/S0095-5108(18)30027-7  0.243
2007 Liu CH, Kim YR, Ren JQ, Eichler F, Rosen BR, Liu PK. Imaging cerebral gene transcripts in live animals Journal of Neuroscience. 27: 713-722. PMID 17234603 DOI: 10.1523/Jneurosci.4660-06.2007  0.243
2018 Duncan C, Eichler F, Musolino PL, Orchard PJ, De Oliveira S, Thrasher AJ, Armant MA, Dansereau C, Lund TC, Miller WP, Raymond GV, Sankar R, Shah AJ, Sevin C, Gaspar HB, et al. Lenti-D Hematopoietic Stem Cell Gene Therapy to Arrest Progression of Cerebral Adrenoleukodystrophy: Interim Results of an International Phase 2/3 Trial Biology of Blood and Marrow Transplantation. 24: S73-S74. DOI: 10.1016/J.Bbmt.2017.12.642  0.243
2007 Eichler F, Van Haren K. Immune Response in Leukodystrophies Pediatric Neurology. 37: 235-244. PMID 17903666 DOI: 10.1016/J.Pediatrneurol.2007.06.011  0.242
2018 Williams DA, Eichler F, Duncan C. Gene Therapy for Cerebral Adrenoleukodystrophy. The New England Journal of Medicine. 378: 490-491. PMID 29385368 DOI: 10.1056/Nejmc1715427  0.239
2011 Bley A, Tifft C, Kahn S, Eichler F. Natural history of infantile GM2 gangliosidosis — Survey of 97 patients Molecular Genetics and Metabolism. 102: S9. DOI: 10.1016/J.Ymgme.2010.11.028  0.239
2020 Stephen CD, Balkwill D, James P, Haxton E, Sassower K, Schmahmann JD, Eichler F, Lewis R. Quantitative oculomotor and nonmotor assessments in late-onset GM2 gangliosidosis. Neurology. PMID 31964693 DOI: 10.1212/Wnl.0000000000008959  0.238
2017 Bohnenpoll J, Eichler F, Schoen G, Hischke S, Denecke J, Hempel M, Kohlschütter A, Bley A. The Natural History of Canavan Disease: Description of 23 New Cases and Comparison with Literature Neuropediatrics. 48: S1-S45. DOI: 10.1055/S-0037-1602948  0.236
2009 Eichler F, Grodd W, Grant E, Sessa M, Bizzi A, Bley A, Kohlschuetter A, Loes D, Kraegeloh-Mann I. 47. Metachromatic leukodystrophy: A scoring system for brain MR observations Molecular Genetics and Metabolism. 96: S22. DOI: 10.1016/J.Ymgme.2008.11.048  0.234
2020 Rochmann C, Minini P, Kissell J, Cox G, Eichler F, Lau H, Stephen C, Fischer T, Hamed A. Natural history of late-onset GM2 gangliosidosis: Four years of data collected at NTSAD annual conferences Molecular Genetics and Metabolism. 129: S136. DOI: 10.1016/J.Ymgme.2019.11.357  0.226
1999 Eichler F, Peham M, Slavc I, Ipsiroglu OS. Intrathecal Administration of Chemotherapy in Children with Brain Tumors: Effects on Cerebral Hemodynamics Pediatric Research. 45: 146A-146A. DOI: 10.1203/00006450-199904020-00866  0.222
2001 Eichler F, Ipsiroglu O, Arif T, Popow C, Heinzl H, Urschitz M, Pollak A. Position dependent changes of cerebral blood flow velocities in premature infants European Journal of Pediatrics. 160: 633-639. PMID 11686511 DOI: 10.1007/S004310100806  0.222
1999 Eichler F, Slavc I, Ipsiroglu OS. Case Report: Effects of Intravenous High-Dose Methotrexate on Cerebral Hemodynamics Pediatric Research. 45: 146A-146A. DOI: 10.1203/00006450-199904020-00867  0.221
1998 Kurtz JE, Deplanque G, Duclos B, Eichler F, Giron C, Limacher JM, Herbrecht R, Maloisel F, Oberling F, Bergerat JP, Dufour P. Paclitaxel-anthracycline combination chemotherapy in relapsing advanced ovarian cancer after platinum-based chemotherapy: a pilot study. Gynecologic Oncology. 70: 414-7. PMID 9790797 DOI: 10.1006/Gyno.1998.5099  0.219
2008 Charnas L, Eichler F, Kohlschuetter A, Tolar J, Orchard PJ. Reply to: Reduced intensity conditioning haematopoietic stem cell transplantation with mesenchymal stromal cells infusion for the treatment of metachromatic leukodystrophy: A case report. Haematologica 2008; 93:e11-13 Haematologica. 93: e47. PMID 18450730 DOI: 10.3324/Haematol.12774  0.215
2014 Krishnamoorthy KS, Eichler F, Rapalino O, Frosch MP. Case records of the Massachusetts General Hospital. Case 14-2014. An 11-month-old girl with developmental delay. The New England Journal of Medicine. 370: 1830-41. PMID 24806163 DOI: 10.1056/Nejmcpc1305987  0.214
2009 Eichler F, Giannikopoulos O, Sathe S, Crawford K, Tifft C. 48. Diagnostic delay in GM2 gangliosidosis Molecular Genetics and Metabolism. 96: S22. DOI: 10.1016/J.Ymgme.2008.11.049  0.205
2014 Berger J, Forss-Petter S, Eichler FS. Pathophysiology of X-linked adrenoleukodystrophy Biochimie. 98: 135-142. PMID 24316281 DOI: 10.1016/j.biochi.2013.11.023  0.2
2015 Clair C, Cohen MJ, Eichler F, Selby KJ, Rigotti NA. The Effect of Cigarette Smoking on Diabetic Peripheral Neuropathy: A Systematic Review and Meta-Analysis. Journal of General Internal Medicine. 30: 1193-203. PMID 25947882 DOI: 10.1007/S11606-015-3354-Y  0.2
2010 Penno A, Eichler F, Hornemann T. The role of deoxy-sphingoid bases in diabetes mellitus and the diabetic sensory neuropathy Chemistry and Physics of Lipids. 163: S15. DOI: 10.1016/J.Chemphyslip.2010.05.048  0.189
2017 Schaefer E, Salen G, Polisecki E, Eichler F, Malloy M, Patamaport P, Geller A, Diffenderfer M, Sacco T, Mehan M. The Diagnosis and Treatment of Cerebrotendinous Xanthomatosis Journal of Clinical Lipidology. 11: 774-775. DOI: 10.1016/J.Jacl.2017.04.008  0.189
2015 Wiesinger C, Eichler FS, Berger J. The genetic landscape of X-linked adrenoleukodystrophy: inheritance, mutations, modifier genes, and diagnosis. The Application of Clinical Genetics. 8: 109-21. PMID 25999754 DOI: 10.2147/TACG.S49590  0.181
2015 Gong Y, Mu D, Prabhakar S, Moser A, Musolino P, Ren J, Breakefield XO, Maguire CA, Eichler FS. Adenoassociated virus serotype 9-mediated gene therapy for x-linked adrenoleukodystrophy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 824-34. PMID 25592337 DOI: 10.1038/Mt.2015.6  0.176
2012 Musolino PL, Rapalino O, Caruso P, Caviness VS, Eichler FS. Hypoperfusion predicts lesion progression in cerebral X-linked adrenoleukodystrophy. Brain : a Journal of Neurology. 135: 2676-83. PMID 22961546 DOI: 10.1093/brain/aws206  0.175
2015 Gong Y, Mu D, Ren J, Moser A, Maguire CA, Eichler FS. 390. Impact of rAAV9-ABCD1 Upon Behavioral Outcome in a Mouse Model of X-ALD Molecular Therapy. 23: S155. DOI: 10.1016/S1525-0016(16)33999-5  0.171
2005 Tan WH, Eichler FS, Hoda S, Lee MS, Baris H, Hanley CA, Grant PE, Krishnamoorthy KS, Shih VE. Isolated sulfite oxidase deficiency: a case report with a novel mutation and review of the literature. Pediatrics. 116: 757-66. PMID 16140720 DOI: 10.1542/Peds.2004-1897  0.167
2015 Fridman V, Oaklander AL, David WS, Johnson EA, Pan J, Novak P, Brown RH, Eichler FS. Natural history and biomarkers in hereditary sensory neuropathy type 1. Muscle & Nerve. 51: 489-95. PMID 25042817 DOI: 10.1002/Mus.24336  0.163
2008 Horvath G, Eichler F, Poskitt K, Stockler-Ipsiroglu S. Cyclophosphamide pulse therapy did not impact disease progression in a patient with childhood cerebral X-linked adrenoleukodystrophy European Journal of Paediatric Neurology. 12: S74. DOI: 10.1016/S1090-3798(08)70254-X  0.158
2012 Friedman J, Roze E, Abdenur JE, Chang R, Gasperini S, Saletti V, Wali GM, Eiroa H, Neville B, Felice A, Parascandalo R, Zafeiriou DI, Arrabal-Fernandez L, Dill P, Eichler FS, et al. Sepiapterin reductase deficiency: a treatable mimic of cerebral palsy. Annals of Neurology. 71: 520-30. PMID 22522443 DOI: 10.1002/Ana.22685  0.157
2008 Eichler FS, Ren JQ, Cossoy M, Rietsch AM, Nagpal S, Moser AB, Frosch MP, Ransohoff RM. Is microglial apoptosis an early pathogenic change in cerebral X-linked adrenoleukodystrophy? Annals of Neurology. 63: 729-42. PMID 18571777 DOI: 10.1002/Ana.21391  0.15
2009 Costello DJ, Eichler AF, Eichler FS. Leukodystrophies classification, diagnosis, and treatment Neurologist. 15: 319-328. PMID 19901710 DOI: 10.1097/NRL.0b013e3181b287c8  0.148
2002 Eichler FS, Wang P, Wityk RJ, Beauchamp NJ, Barker PB. Diffuse metabolic abnormalities in reversible posterior leukoencephalopathy syndrome American Journal of Neuroradiology. 23: 833-837. PMID 12006287  0.134
2010 Mahmood A, Berry J, Wenger DA, Escolar M, Sobeih M, Raymond G, Eichler FS. Metachromatic leukodystrophy: a case of triplets with the late infantile variant and a systematic review of the literature. Journal of Child Neurology. 25: 572-80. PMID 20038527 DOI: 10.1177/0883073809341669  0.133
2008 Schmahmann JD, Smith EE, Eichler FS, Filley CM. Cerebral white matter: neuroanatomy, clinical neurology, and neurobehavioral correlates. Annals of the New York Academy of Sciences. 1142: 266-309. PMID 18990132 DOI: 10.1196/Annals.1444.017  0.133
2015 Musolino PL, Gong Y, Snyder JM, Jimenez S, Lok J, Lo EH, Moser AB, Grabowski EF, Frosch MP, Eichler FS. Brain endothelial dysfunction in cerebral adrenoleukodystrophy. Brain : a Journal of Neurology. PMID 26377633 DOI: 10.1093/Brain/Awv250  0.126
2010 Braverman N, Eichler F. Peroxisomal Disorders and Neurological Disease Encyclopedia of Neuroscience. 579-588. DOI: 10.1016/B978-008045046-9.02011-8  0.119
2014 Eichler FS. Metachromatic Leukodystrophy and Multiple Sulfatase Deficiency Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease: Fifth Edition. 331-336. DOI: 10.1016/B978-0-12-410529-4.00029-2  0.107
2011 Bley AE, Giannikopoulos OA, Hayden D, Kubilus K, Tifft CJ, Eichler FS. Natural history of infantile G M2 gangliosidosis Pediatrics. 128: e1233-e1241. PMID 22025593 DOI: 10.1542/peds.2011-0078  0.096
2012 Okita BMD, Utz J, Eichler FS, Ziegler RS, Leduc RL, Whitley CB. A Natural History of Hexosaminidase Deficiency Molecular Genetics and Metabolism. 105: S61-S62. DOI: 10.1016/j.ymgme.2011.11.164  0.094
1999 Ipsiroglu OS, Eichler F, Stoeckler-Ipsiroglu S. Cerebral Doppler sonography of the neonate: A resume after 20 years and future aspects Clinics in Perinatology. 26: 905-946. PMID 10572729  0.092
2016 Eichler FS, Duncan C, Amartino H, Aziz-Bose R, Baruchel A, Dansereau C, Dalle J, Gaspar HB, Gissen P, Kohn DB, Larghero J, Lund TC, Miller WP, Musolino PL, O'Meara T, et al. 250. A Phase 2/3 Study of the Efficacy and Safety of Ex Vivo Gene Therapy with Lenti-D TM Lentiviral Vector for the Treatment of Cerebral Adrenoleukodystrophy Molecular Therapy. 24: S98-S99. DOI: 10.1016/S1525-0016(16)33059-3  0.087
2008 Moll NM, Rietsch AM, Ransohoff AJ, Cossoy MB, Huang D, Eichler FS, Trapp BD, Ransohoff RM. Cortical demyelination in PML and MS: Similarities and differences. Neurology. 70: 336-43. PMID 17914063 DOI: 10.1212/01.WNL.0000284601.54436.e4  0.084
1996 Riegel P, Ruimy R, De Briel D, Eichler F, Bergerat JP, Christen R, Monteil H. Bacteremia due to Gordona sputi in an immunocompromised patient Journal of Clinical Microbiology. 34: 2045-2047. PMID 8818912  0.08
2009 Han G, Gupta SD, Gable K, Niranjanakumari S, Moitra P, Eichler F, Brown RH, Harmon JM, Dunn TM. Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities (Proceedings of the National Academy of Sciences of the United States of America (2009) 106, 20, (8186-8191) DOI: 10.1073/pnas.0811269106) Proceedings of the National Academy of Sciences of the United States of America. 106: 9931. DOI: 10.1073/pnas.0905301106  0.072
2010 Krishnamoorthy KS, Eichler FS, Goyal NA, Small JE, Snuderl M. Case records of the Massachusetts General Hospital. Case 3-2010. A 5-month-old boy with developmental delay and irritability. The New England Journal of Medicine. 362: 346-56. PMID 20107221 DOI: 10.1056/NEJMcpc0907806  0.068
1996 Eichler F, Keiling R. Survival results after 10 years of 39 inflammatory breast cancer patients treated by two different neoadjuvant chemotherapy protocols | SURVIE A 10 ANS DE 39 PATIENTES PORTEUSES D'UN CANCER DU SEIN A CINETIQUE RAPIDE TRAITEES SELON DEUX PROTOCOLES DE CHIMIOTHERAPIE NEOADJUVANTS DIFFERENTS Bulletin Du Cancer. 83: 234-238. PMID 8695926  0.068
1952 PETUELY F, EICHLER F. Growth of lactobacillus bifidus on synthetic media. | Uber die Züchtung des Lactobacillus bifidus auf vollsynthetischem Nähroboden Biochemische Zeitschrift. 322: 463-466. PMID 14953924  0.064
2014 Wesselmann ED, Williams KD, Pryor JB, Eichler FA, Gill DM, Hogue JD. Revisiting Schachter's research on rejection, deviance, and communication (1951) Social Psychology. 45: 164-169. DOI: 10.1027/1864-9335/A000180  0.062
2014 Musolino PL, Lund TC, Pan J, Escolar ML, Paker AM, Duncan CN, Eichler FS. Hematopoietic stem cell transplantation in the leukodystrophies: a systematic review of the literature. Neuropediatrics. 45: 169-74. PMID 24459069 DOI: 10.1055/s-0033-1364179  0.062
2011 Mathelin C, Croce S, Rault S, Gharbi M, Eichler F, Gairard B, Coumaros G, Koehl C. Clinical usefulness of circulating ECD/HER-2 measurement for breast cancer patients' management | Doit-on doser le marqueur circulant ECD/HER-2 chez les patientes atteintes d'un cancer mammaire ? Presse Medicale. 40: 126-137. PMID 21074348 DOI: 10.1016/j.lpm.2010.10.004  0.061
2009 Costello DJ, Eichler FS, Grant PE, Auluck PK. Case records of the Massachusetts General Hospital. Case 1-2009. A 57-year-old man with progressive cognitive decline. The New England Journal of Medicine. 360: 171-81. PMID 19129531 DOI: 10.1056/Nejmcpc0807820  0.058
1998 Massard G, Eichler F, Gasser B, Bergerat JP, Wihlm JM, Bosl GJ. Recurrence of the mediastinal growing teratoma syndrome [8] (multiple letters) Annals of Thoracic Surgery. 66: 605-606. PMID 9725431 DOI: 10.1016/S0003-4975(98)00420-2  0.057
2012 Ladoire S, Mignot G, Dalban C, Chevriaux A, Arnould L, Rébé C, Apetoh L, Boidot R, Penault-Llorca F, Fumoleau P, Roché H, Spielmann M, Levy C, Lortholary A, Eichler F, et al. FOXP3 expression in cancer cells and anthracyclines efficacy in patients with primary breast cancer treated with adjuvant chemotherapy in the phase III UNICANCER-PACS 01 trial Annals of Oncology. 23: 2552-2561. PMID 22431701 DOI: 10.1093/annonc/mds028  0.057
1951 EICHLER F. Rational therapeutics. | Rationelle Therapie Das Deutsche Gesundheitswesen. 6: 219-221. PMID 14822681  0.055
1987 Vetter D, Eichler F, Doffoël M, Krzisch C, Gut JP, Willemin B, Reville M, North ML, Keiling R, Bockel R. [Determination of sub-populations of circulating T lymphocytes in alcoholic cirrhosis using monoclonal antibodies OKT3, 4, 5, Leu 2 and Leu 15. Effect of hepatitis B virus infection]. GastroentéRologie Clinique Et Biologique. 11: 790-4. PMID 2962894  0.051
2000 Delis A, Eichler F. Risk and perioperative procedures in a patient with long-term lithium therapy | Gefahren und perioperatives vorgehen bei einer patientin unter lithium- dauertherapie Anasthesiologie Intensivmedizin Notfallmedizin Schmerztherapie. 35: 173-176. PMID 10768053 DOI: 10.1055/s-2000-12980  0.051
2000 Levine BA, Eichler F, Ingeholm ML, Moser H. A multi-center digital MRI network for Adrenoleukodystrophy (ALD) Proceedings of the Ieee/Embs Region 8 International Conference On Information Technology Applications in Biomedicine, Itab. 214-219.  0.045
2006 Roché H, Fumoleau P, Spielmann M, Canon JL, Delozier T, Serin D, Symann M, Kerbrat P, Soulié P, Eichler F, Viens P, Monnier A, Vindevoghel A, Campone M, Goudier MJ, et al. Sequential adjuvant epirubicin-based and docetaxel chemotherapy for node-positive breast cancer patients: The FNCLCC PACS 01 trial Journal of Clinical Oncology. 24: 5664-5671. PMID 17116941 DOI: 10.1200/JCO.2006.07.3916  0.045
1999 Eichler FAW, Paul M. Life-threatening perioperative complications in Ehlers-Danlos syndrome with dissection of the internal carotid protery | Lebensbedrohliche perioperative komplikationen bei ehlers-danlos syndrom mit dissektion der arteria carotis interna Anasthesiologie Intensivmedizin Notfallmedizin Schmerztherapie. 34: 720-722. PMID 10609043 DOI: 10.1055/s-1999-221  0.044
2000 Urschitz MS, Eichler F, Popow C, Ipsiroglu OS. Evaluation of the cardiorespiratory monitor SpiroGuard C for infants | Evaluierung des herz-atem-uberwachungsgerates SpiroGuard C fur sauglinge: Verbesserte erfassung von respiratorischen ereignissen durch neue sensorik und intelligentes alarmmanagement? Wiener Klinische Wochenschrift. 112: 226-233. PMID 10763536  0.044
2007 Auluck PK, Barnett SM, Eichler FS, Hedley‐Whyte ET. Neonatal adrenoleukodystrophy with long‐term survival The Faseb Journal. 21. DOI: 10.1096/fasebj.21.5.a401-c  0.043
2006 Noth F, Eichler F. Accident with an 8-month-old infant | Verkehrsunfall mit einem acht monate alten säugling Notarzt. 22: 15-17. DOI: 10.1055/s-2004-834579  0.042
1999 Dautel D, Gerout AC, Eichler F, Koffel JC. Search of an ifosfamide encephalopathy treatment protocol by methylene blue | Recherche d'un protocole de traitement des encephalopathies a ifosfamide par le bleu de methylene Journal De Pharmacie Clinique. 18: 25-27.  0.04
2002 Kurz H, Neunteufl R, Eichler F, Urschitz M, Tiefenthaler M. Does professional counseling improve infant home monitoring? Evaluation of an intensive instruction program for families using home monitoring on their babies Wiener Klinische Wochenschrift. 114: 801-806. PMID 12416288  0.039
2007 Auluck PK, Barnett SM, Eichler FS, Hedley-Whyte ET. Neonatal adrenoleukodystrophy with long-term survival Journal of Neuropathology and Experimental Neurology. 66: 452. DOI: 10.1097/01.jnen.0000268950.31191.63  0.037
1995 Limacher J, Duclos B, Wihlm J, Leveque D, Dufour P, Eichler F, Keiling R, Bergerat J. 945 Phase I study of high dose 5-fluorouracil and folinic acid in weekly continuous infusion European Journal of Cancer. 31: S197. DOI: 10.1016/0959-8049(95)96194-I  0.036
2008 Soltesz S, Gerbershagen MU, Pantke B, Eichler F, Molter G. Parecoxib versus dipyrone (metamizole) for postoperative pain relief after hysterectomy: A prospective, single-centre, randomized, double-blind trial Clinical Drug Investigation. 28: 421-428. PMID 18544002 DOI: 10.2165/00044011-200828070-00003  0.036
2004 Eichler F, Decker T, Müller E, Kasper SM, Rütt J, Grond S. Efficacy and safety of 0.1 mg of intrathecal morphine in arthroscopic knee joint surgery. A double-blind, randomized clinical trial | Spinalanästhesie bei der arthroskopie des kniegelenks: Effektivität und sicherheit von morphin 0,1 mg als zusatz - eine doppelblinde, randomisierte untersuchung Schmerz. 18: 515-519. PMID 15586301 DOI: 10.1007/s00482-003-0294-y  0.035
2010 Frenzel L, Javier RM, Eichler F, Zollner G, Sibilia J. Multiple bone metastases with fluid-fluid levels | Métastases osseuses liquidiennes multiples Revue Du Rhumatisme (Edition Francaise). 77: 201-203. DOI: 10.1016/j.rhum.2009.05.015  0.032
1999 Eichler F, Arif T, Urschitz M, Ipsiroglu O, Pollak A. Position Dependent Perfusion of The Vertebrobasilar System in Premature Infants < 1750 Gram Pediatric Research. 45: 25A-25A. DOI: 10.1203/00006450-199905020-00100  0.031
2004 Gerling V, Römer J, Eichler FAW. Rupture of a splenic aneurism in an emergency situation | Ruptur eines milzarterienaneurysmas im notarztdienst Anasthesiologie Intensivmedizin Notfallmedizin Schmerztherapie. 39: 735-738. PMID 15605297 DOI: 10.1055/s-2004-826089  0.03
1998 Meuser T, Eichler F, Grond S, Winkler B, Lehmann KA. Anaesthesia for caesarean section in Germany. A survey | Anasthesieverfahren zur sectio caesarea in Deutschland. Eine umfrage Anaesthesist. 47: 557-564. PMID 9740929 DOI: 10.1007/s001010050596  0.029
1997 Eichler F, Achour NE, Vetter JM, Bergerat JP, Jacqmin D. Neurectodermal differentiation of an embryonal carcinoma of the testis | Differenciation neurectodermique d'un carcinome embryonnaire du testicule Bulletin Du Cancer. 84: 630-633. PMID 9295867  0.028
1911 Eichler F, Latz B. Experimentelle studien über die beeinflussung der gallensekretion durch neuere cholagoge. III. Iridin und evonymin Digestion. 17: 133-135. DOI: 10.1159/000192105  0.027
1950 EICHLER F. Palpation of epigastrium. | Uber die Palpation des Oberbauches Das Deutsche Gesundheitswesen. 5: 1168. PMID 14783980  0.025
2001 Fumoleau P, Tubiana-Hulin M, Romieu G, Namer M, Delva R, Guastalla JP, Lotz JP, Kerbrat P, Pujade-Lauraine E, Eichler F, Dohollou N, MacGrogan G, Quinaux E, Grau B. A randomized phase II study of 4 or 6 cycles of Adriamycin/Taxol® (paclitaxel) as neoadjuvant treatment of breast cancer Breast Cancer Research and Treatment. 69: 298.  0.024
1998 Eichler F, Schulz D. The nitrogen reduction programme in the Federal Republic of Germany Environmental Pollution. 102: 609-617. DOI: 10.1016/S0269-7491(98)80089-4  0.022
1954 Petuely F, Eichler F. Beeinflussung der Wuchsformen des Lactobacillus bifidus Zeitschrift Fur Naturforschung - Section B Journal of Chemical Sciences. 9: 229-234. DOI: 10.1515/znb-1954-0314  0.022
2004 Alsweiler W, Büttner A, Eichler F, Frebel W, Gasch B, Gräber T, Gretenkort P, Heister U, Hunold R, Koerner-Goebel H, Kremer A, Lechleuthner A, Müller C, Sirtl C, Stahlberg P, et al. Emergency physicians in Northrhine-Westphalia: Occupational contentment and subjective education level - Results of a survey | Notärzte in NRW: Berufszufriedenheit und subjektiver fortbildungsstand - Umfrageergebnis der arbeitsgruppe qualitätsmanagement der AGNNW Notarzt. 20: 133-138. DOI: 10.1055/s-2003-815019  0.022
2010 Frenzel L, Javier RM, Eichler F, Zollner G, Sibilia J. Multiple fluid-filled bone metastases. Joint, Bone, Spine : Revue Du Rhumatisme. 77: 171-3. PMID 20194045 DOI: 10.1016/j.jbspin.2010.01.006  0.02
1956 Zukriegel H, Eichler F. Korrelationen zwischen biologischen Vorgängen und Lichtechtheitsgesetzmäßigkeiten von organischen Farbstoffen - Kurze Mitteilung Monatshefte FüR Chemie. 87: 371-372. DOI: 10.1007/BF00902557  0.02
1994 Eichler F, Krueger GRF. Effects of non-specific immunostimulants (echinacin, isoprinosine and thymus factors) on the infection and antigen expression in herpesvirus-6 exposed human lymphoid cells In Vivo. 8: 565-575. PMID 7534493  0.02
1936 Eichler F. Kompensations-Meßgeräte mit selbsttätiger Abgleichung: I. Schrittweise Abgleichung Technisches Messen. 61: 288-293. DOI: 10.1524/teme.1936.6172.jg.288  0.017
2012 Schauberger G, Schmitzer R, Kamp M, Sowa A, Koch R, Eckhof W, Eichler F, Grimm E, Kypke J, Hartung E. Empirical model derived from dispersion calculations to determine separation distances between livestock buildings and residential areas to avoid odour nuisance Atmospheric Environment. 46: 508-515. DOI: 10.1016/j.atmosenv.2011.08.025  0.016
1988 Eichler F, Keiling R. Variations in the percentages of lymphocyte subtypes during the menstrual cycle in women Biomedicine and Pharmacotherapy. 42: 285-288. PMID 3191205  0.015
1933 Eichler F. Trägheitsbehaftete Oszillographen: Bauarten und Zubehör Technisches Messen. 25: 95-98. DOI: 10.1524/teme.1933.2536.jg.95  0.012
2006 Eichler F. Occupational perspective: A medical leader rescue service | Berufsperspektive: Ärztlicher leiter rettungsdienst Anasthesiologie Intensivmedizin Notfallmedizin Schmerztherapie. 41: 674-677.  0.012
1932 Eichler F. Trägheitsbehaftete Oszillographen: Grundsätzliches über Wirkungsweise und Aufbau Technisches Messen. 13: 428-431. DOI: 10.1524/teme.1932.1324.jg.428  0.012
2012 Pei L, Bar-Yam S, Byers-Corbin J, Casagrande R, Eichler F, Lin A, Österreicher M, Regardh PC, Turlington RD, Oye KA, Torgersen H, Guan ZJ, Wei W, Schmidt M. Regulatory Frameworks for Synthetic Biology Synthetic Biology: Industrial and Environmental Applications. 157-226. DOI: 10.1002/9783527659296.ch5  0.01
2012 Rejŝek K, Miŝic M, Eichler F. Sustainable forestry and iron compounds in karstic soils: Qualitative and semi-Quantitative results focused on the occurrence of Fe-compounds on mineral particles Journal of Forest Science. 58: 410-424.  0.01
2009 Šušteršič F, Rejšek K, Mišič M, Eichler F. The role of loamy sediment (terra rossa) in the context of steady state karst surface lowering Geomorphology. 106: 35-45. DOI: 10.1016/j.geomorph.2008.09.024  0.01
2003 Eichler F. Deutsche und europäische Gesetzgebung zum Immissionsschutz Vdi Berichte. 1-10.  0.01
1999 Eichler F, Ditz J. Staining methods used for pH monitoring at the solid-liquid interface - a microscopic study of wetted sandstone Acta Universitatis Carolinae, Geologica. 43: 545-549.  0.01
1936 Eichler F. Kompensations- Meßgeräte mit selbsttätiger Abgleichung II. Stetige Abgleichung Technisches Messen. 61: 488-491. DOI: 10.1524/teme.1936.6172.jg.488  0.01
1931 Obering, Eichler F. Luftdämpfungen für Meßgeräte Anwendung und konstruktive Durchbildung Technisches Messen. 1: 371-372. DOI: 10.1524/teme.1931.112.jg.371  0.01
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