Brian Hendrich - Publications

Affiliations: 
Biology University of Cambridge, Cambridge, England, United Kingdom 

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Lando D, Ma X, Cao Y, Jartseva A, Stevens TJ, Boucher W, Reynolds N, Montibus B, Hall D, Lackner A, Ragheb R, Leeb M, Hendrich BD, Laue ED. Enhancer-promoter interactions are reconfigured through the formation of long-range multiway hubs as mouse ES cells exit pluripotency. Molecular Cell. PMID 38490199 DOI: 10.1016/j.molcel.2024.02.015  0.386
2023 Montibus B, Ragheb R, Diamanti E, Dunn SJ, Reynolds N, Hendrich B. The Nucleosome Remodelling and Deacetylation complex coordinates the transcriptional response to lineage commitment in pluripotent cells. Biology Open. PMID 38149716 DOI: 10.1242/bio.060101  0.411
2020 Ragheb R, Gharbi S, Cramard J, Ogundele O, Kloet SL, Burgold T, Vermeulen M, Reynolds N, Hendrich B. Differential regulation of lineage commitment in human and mouse primed pluripotent stem cells by the nucleosome remodelling and deacetylation complex. Stem Cell Research. 46: 101867. PMID 32535494 DOI: 10.1016/J.Scr.2020.101867  0.519
2019 Burgold T, Barber M, Kloet S, Cramard J, Gharbi S, Floyd R, Kinoshita M, Ralser M, Vermeulen M, Reynolds N, Dietmann S, Hendrich B. The Nucleosome Remodelling and Deacetylation complex suppresses transcriptional noise during lineage commitment. The Embo Journal. PMID 31036553 DOI: 10.15252/Embj.2018100788  0.498
2018 Link S, Spitzer RMM, Sana M, Torrado M, Völker-Albert MC, Keilhauer EC, Burgold T, Pünzeler S, Low JKK, Lindström I, Nist A, Regnard C, Stiewe T, Hendrich B, Imhof A, et al. PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex. Nature Communications. 9: 4300. PMID 30327463 DOI: 10.1038/S41467-018-06665-5  0.463
2018 Bornelöv S, Reynolds N, Xenophontos M, Gharbi S, Johnstone E, Floyd R, Ralser M, Signolet J, Loos R, Dietmann S, Bertone P, Hendrich B. The Nucleosome Remodeling and Deacetylation Complex Modulates Chromatin Structure at Sites of Active Transcription to Fine-Tune Gene Expression. Molecular Cell. 71: 56-72.e4. PMID 30008319 DOI: 10.1016/J.Molcel.2018.06.003  0.49
2018 Basu S, Needham LM, Lando D, Taylor EJR, Wohlfahrt KJ, Shah D, Boucher W, Tan YL, Bates LE, Tkachenko O, Cramard J, Lagerholm BC, Eggeling C, Hendrich B, Klenerman D, et al. FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells. Nature Communications. 9: 2520. PMID 29955052 DOI: 10.1038/S41467-018-04486-0  0.319
2018 Miller A, Hendrich B. Chromatin Remodelling Proteins and Cell Fate Decisions in Mammalian Preimplantation Development. Advances in Anatomy, Embryology, and Cell Biology. 229: 3-14. PMID 29177761 DOI: 10.1007/978-3-319-63187-5_2  0.515
2017 Loughran SJ, Comoglio F, Hamey FK, Giustacchini A, Errami Y, Earp E, Göttgens B, Jacobsen SEW, Mead AJ, Hendrich B, Green AR. Mbd3/NuRD controls lymphoid cell fate and inhibits tumorigenesis by repressing a B cell transcriptional program. The Journal of Experimental Medicine. PMID 28899870 DOI: 10.1084/Jem.20161827  0.477
2017 Liang Z, Brown K, Carroll T, Taylor B, Ferreirós Vidal I, Hendrich B, Rueda D, Fisher AG, Merkenschlager M. A high-resolution map of transcriptional repression. Elife. 6. PMID 28318487 DOI: 10.7554/Elife.22767  0.47
2017 Stevens TJ, Lando D, Basu S, Atkinson LP, Cao Y, Lee SF, Leeb M, Wohlfahrt KJ, Boucher W, O'Shaughnessy-Kirwan A, Cramard J, Faure AJ, Ralser M, Blanco E, Morey L, ... ... Hendrich B, et al. 3D structures of individual mammalian genomes studied by single-cell Hi-C. Nature. PMID 28289288 DOI: 10.1038/Nature21429  0.367
2017 Loughran S, Comoglio F, Giustacchini A, Errami Y, Earp E, Hamey F, Gottgens B, Jacobsen SE, Mead A, Hendrich B, Green A. Mbd3/NuRD-mediated chromatin remodelling controls lymphoid cell fate and inhibits tumorigenesis by opposing transcriptional pioneering during B cell programming Experimental Hematology. 53. DOI: 10.1016/J.Exphem.2017.06.178  0.409
2016 Miller A, Ralser M, Kloet SL, Loos R, Nishinakamura R, Bertone P, Vermeulen M, Hendrich B. Sall4 controls differentiation of pluripotent cells independently of the Nucleosome Remodelling and Deacetylation (NuRD) complex. Development (Cambridge, England). PMID 27471257 DOI: 10.1242/Dev.139113  0.549
2016 Zhang W, Aubert A, Gomez de Segura JM, Karuppasamy M, Basu S, Murthy A, Diamante A, Drury TA, Balmer J, Cramard J, Watson AA, Lando D, Lee SF, Palayret M, Kloet S, ... ... Hendrich B, et al. The Nucleosome Remodeling and Deacetylase Complex NuRD is built from preformed catalytically active sub-modules. Journal of Molecular Biology. PMID 27117189 DOI: 10.1016/J.Jmb.2016.04.025  0.396
2015 O'Shaughnessy-Kirwan A, Signolet J, Costello I, Gharbi S, Hendrich B. Constraint of gene expression by the chromatin remodelling protein CHD4 facilitates lineage specification. Development (Cambridge, England). 142: 2586-97. PMID 26116663 DOI: 10.1242/Dev.125450  0.493
2015 Knock E, Pereira J, Lombard PD, Dimond A, Leaford D, Livesey FJ, Hendrich B. The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex. Neural Development. 10: 13. PMID 25934499 DOI: 10.1186/S13064-015-0040-Z  0.661
2015 Signolet J, Hendrich B. The function of chromatin modifiers in lineage commitment and cell fate specification. The Febs Journal. 282: 1692-702. PMID 25354247 DOI: 10.1111/Febs.13132  0.521
2014 dos Santos RL, Tosti L, Radzisheuskaya A, Caballero IM, Kaji K, Hendrich B, Silva JC. MBD3/NuRD facilitates induction of pluripotency in a context-dependent manner. Cell Stem Cell. 15: 102-10. PMID 24835571 DOI: 10.1016/J.Stem.2014.04.019  0.473
2013 O'Shaughnessy A, Hendrich B. CHD4 in the DNA-damage response and cell cycle progression: not so NuRDy now. Biochemical Society Transactions. 41: 777-82. PMID 23697937 DOI: 10.1042/Bst20130027  0.44
2013 Reynolds N, O'Shaughnessy A, Hendrich B. Transcriptional repressors: multifaceted regulators of gene expression. Development (Cambridge, England). 140: 505-12. PMID 23293282 DOI: 10.1242/Dev.083105  0.462
2012 Latos PA, Helliwell C, Mosaku O, Dudzinska DA, Stubbs B, Berdasco M, Esteller M, Hendrich B. NuRD-dependent DNA methylation prevents ES cells from accessing a trophectoderm fate. Biology Open. 1: 341-52. PMID 23213424 DOI: 10.1242/Bio.2012513  0.566
2012 Bertulat B, De Bonis ML, Della Ragione F, Lehmkuhl A, Milden M, Storm C, Jost KL, Scala S, Hendrich B, D'Esposito M, Cardoso MC. MeCP2 dependent heterochromatin reorganization during neural differentiation of a novel Mecp2-deficient embryonic stem cell reporter line. Plos One. 7: e47848. PMID 23112857 DOI: 10.1371/Journal.Pone.0047848  0.52
2012 Reynolds N, Latos P, Hynes-Allen A, Loos R, Leaford D, O'Shaughnessy A, Mosaku O, Signolet J, Brennecke P, Kalkan T, Costello I, Humphreys P, Mansfield W, Nakagawa K, Strouboulis J, ... ... Hendrich B, et al. NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment. Cell Stem Cell. 10: 583-94. PMID 22560079 DOI: 10.1016/J.Stem.2012.02.020  0.499
2012 McDonel P, Demmers J, Tan DW, Watt F, Hendrich BD. Sin3a is essential for the genome integrity and viability of pluripotent cells. Developmental Biology. 363: 62-73. PMID 22206758 DOI: 10.1016/J.Ydbio.2011.12.019  0.344
2012 Reynolds N, Salmon-Divon M, Dvinge H, Hynes-Allen A, Balasooriya G, Leaford D, Behrens A, Bertone P, Hendrich B. NuRD-mediated deacetylation of H3K27 facilitates recruitment of Polycomb Repressive Complex 2 to direct gene repression. The Embo Journal. 31: 593-605. PMID 22139358 DOI: 10.1038/Emboj.2011.431  0.546
2011 Nascimento EM, Cox CL, MacArthur S, Hussain S, Trotter M, Blanco S, Suraj M, Nichols J, Kübler B, Benitah SA, Hendrich B, Odom DT, Frye M. The opposing transcriptional functions of Sin3a and c-Myc are required to maintain tissue homeostasis. Nature Cell Biology. 13: 1395-405. PMID 22101514 DOI: 10.1038/Ncb2385  0.421
2011 Aguilera C, Nakagawa K, Sancho R, Chakraborty A, Hendrich B, Behrens A. c-Jun N-terminal phosphorylation antagonises recruitment of the Mbd3/NuRD repressor complex. Nature. 469: 231-5. PMID 21196933 DOI: 10.1038/Nature09607  0.396
2009 Martín Caballero I, Hansen J, Leaford D, Pollard S, Hendrich BD. The methyl-CpG binding proteins Mecp2, Mbd2 and Kaiso are dispensable for mouse embryogenesis, but play a redundant function in neural differentiation. Plos One. 4: e4315. PMID 19177165 DOI: 10.1371/journal.pone.0004315  0.453
2009 McDonel P, Costello I, Hendrich B. Keeping things quiet: Roles of NuRD and Sin3 co-repressor complexes during mammalian development The International Journal of Biochemistry & Cell Biology. 41: 108-116. PMID 18775506 DOI: 10.1016/J.Biocel.2008.07.022  0.497
2007 Barr H, Hermann A, Berger J, Tsai HH, Adie K, Prokhortchouk A, Hendrich B, Bird A. Mbd2 contributes to DNA methylation-directed repression of the Xist gene. Molecular and Cellular Biology. 27: 3750-7. PMID 17353271 DOI: 10.1128/Mcb.02204-06  0.489
2007 Kaji K, Nichols J, Hendrich B. Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells. Development (Cambridge, England). 134: 1123-32. PMID 17287250 DOI: 10.1242/Dev.02802  0.528
2006 Kaji K, Caballero IM, MacLeod R, Nichols J, Wilson VA, Hendrich B. The NuRD component Mbd3 is required for pluripotency of embryonic stem cells. Nature Cell Biology. 8: 285-92. PMID 16462733 DOI: 10.1038/Ncb1372  0.516
2006 Prokhortchouk A, Sansom O, Selfridge J, Caballero IM, Salozhin S, Aithozhina D, Cerchietti L, Meng FG, Augenlicht LH, Mariadason JM, Hendrich B, Melnick A, Prokhortchouk E, Clarke A, Bird A. Kaiso-deficient mice show resistance to intestinal cancer. Molecular and Cellular Biology. 26: 199-208. PMID 16354691 DOI: 10.1128/Mcb.26.1.199-208.2006  0.393
2005 Hutchins AS, Artis D, Hendrich BD, Bird AP, Scott P, Reiner SL. Cutting edge: a critical role for gene silencing in preventing excessive type 1 immunity. Journal of Immunology (Baltimore, Md. : 1950). 175: 5606-10. PMID 16237047 DOI: 10.4049/Jimmunol.175.9.5606  0.371
2005 Caballero IM, Hendrich B. MeCP2 in neurons: closing in on the causes of Rett syndrome. Human Molecular Genetics. 14: R19-26. PMID 15809268 DOI: 10.1093/Hmg/Ddi102  0.403
2003 Sansom OJ, Berger J, Bishop SM, Hendrich B, Bird A, Clarke AR. Deficiency of Mbd2 suppresses intestinal tumorigenesis. Nature Genetics. 34: 145-7. PMID 12730693 DOI: 10.1038/Ng1155  0.421
2003 Hendrich B, Tweedie S. The methyl-CpG binding domain and the evolving role of DNA methylation in animals. Trends in Genetics : Tig. 19: 269-77. PMID 12711219 DOI: 10.1016/S0168-9525(03)00080-5  0.403
2002 Prokhortchouk E, Hendrich B. Methyl-CpG binding proteins and cancer: are MeCpGs more important than MBDs? Oncogene. 21: 5394-9. PMID 12154402 DOI: 10.1038/Sj.Onc.1205631  0.372
2002 Hutchins AS, Mullen AC, Lee HW, Sykes KJ, High FA, Hendrich BD, Bird AP, Reiner SL. Gene silencing quantitatively controls the function of a developmental trans-activator. Molecular Cell. 10: 81-91. PMID 12150909 DOI: 10.1016/S1097-2765(02)00564-6  0.4
2002 Millar CB, Guy J, Sansom OJ, Selfridge J, MacDougall E, Hendrich B, Keightley PD, Bishop SM, Clarke AR, Bird A. Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice. Science (New York, N.Y.). 297: 403-5. PMID 12130785 DOI: 10.1126/Science.1073354  0.398
2002 Santos F, Hendrich B, Reik W, Dean W. Dynamic reprogramming of DNA methylation in the early mouse embryo. Developmental Biology. 241: 172-82. PMID 11784103 DOI: 10.1006/Dbio.2001.0501  0.45
2001 Hendrich B, Bickmore W. Human diseases with underlying defects in chromatin structure and modification Human Molecular Genetics. 10: 2233-2242. PMID 11673406 DOI: 10.1093/Hmg/10.20.2233  0.494
2001 Prokhortchouk A, Hendrich B, Jørgensen H, Ruzov A, Wilm M, Georgiev G, Bird A, Prokhortchouk E. The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor Genes & Development. 15: 1613-1618. PMID 11445535 DOI: 10.1101/Gad.198501  0.473
2001 Hendrich B, Guy J, Ramsahoye B, Wilson VA, Bird A. Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development. Genes & Development. 15: 710-23. PMID 11274056 DOI: 10.1101/Gad.194101  0.504
2001 Guy J, Hendrich B, Holmes M, Martin JE, Bird AP. A mouse Mecp2-null mutation causes neurological symptoms that mimic rett syndrome Nature Genetics. 27: 322-326. PMID 11242117 DOI: 10.1038/85899  0.353
2000 Hendrich B. Human genetics: Methylation moves into medicine Current Biology. 10. PMID 10662663 DOI: 10.1016/S0960-9822(00)00286-4  0.407
2000 Hendrich B, Ng H, Guy J, Bird A. Functional Studies of Proteins that bind to Methylated DNA Biochemical Society Transactions. 28. DOI: 10.1042/Bst028A113C  0.401
1999 Bader S, Walker M, Hendrich B, Bird A, Bird C, Hooper M, Wyllie A. Somatic frameshift mutations in the MBD4 gene of sporadic colon cancers with mismatch repair deficiency. Oncogene. 18: 8044-8047. PMID 10637515 DOI: 10.1038/Sj.Onc.1203229  0.316
1999 Tweedie S, Ng HH, Barlow AL, Turner BM, Hendrich B, Bird A. Vestiges of a DNA methylation system in Drosophila melanogaster? Nature Genetics. 23: 389-90. PMID 10581020 DOI: 10.1038/70490  0.478
1999 Hendrich B, Hardeland U, Ng H, Jiricny J, Bird A. The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites Nature. 401: 301-304. PMID 10499592 DOI: 10.1038/45843  0.408
1999 Ng HH, Zhang Y, Hendrich B, Johnson CA, Turner BM, Erdjument-Bromage H, Tempst P, Reinberg D, Bird A. MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex. Nature Genetics. 23: 58-61. PMID 10471499 DOI: 10.1038/12659  0.516
1999 Hendrich B, Abbott C, McQueen H, Chambers D, Cross S, Bird A. Genomic structure and chromosomal mapping of the murine and human Mbd1, Mbd2, Mbd3, and Mbd4 genes. Mammalian Genome. 10: 906-912. PMID 10441743 DOI: 10.1007/S003359901112  0.422
1998 Hendrich B, Bird A. Identification and characterization of a family of mammalian methyl-CpG binding proteins. Molecular and Cellular Biology. 18: 6538-6547. PMID 9774669 DOI: 10.1128/Mcb.18.11.6538  0.532
1998 Hendrich B, Bird A. Identification and characterization of a family of mammalian methyl CpG-binding proteins Genetics Research. 72: 59-72. DOI: 10.1017/S0016672398533307  0.372
1995 Hendrich BD, Willard HF. Epigenetic regulation of gene expression: The effect of altered chromatin structure from yeast to mammals Human Molecular Genetics. 4: 1765-1777. PMID 8541877 DOI: 10.1093/Hmg/4.Suppl_1.1765  0.479
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