Donald Metcalf, MD PhD - Publications

Affiliations: 
1954-2014 The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia 
Area:
Hematology, stem cells, cytokines

264 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Jackson JT, Shields BJ, Shi W, Di Rago L, Metcalf D, Nicola NA, McCormack MP. Hhex Regulates Hematopoietic Stem Cell Self-Renewal and Stress Hematopoiesis via Repression of Cdkn2a. Stem Cells (Dayton, Ohio). PMID 28577303 DOI: 10.1002/Stem.2648  0.408
2016 Metcalf D. Growth and Differentiation Factors. Microbiology Spectrum. 4. PMID 27726812 DOI: 10.1128/Microbiolspec.Mchd-0004-2015  0.426
2016 Sheikh BN, Yang Y, Schreuder J, Nilsson SK, Bilardi R, Carotta S, McRae HM, Metcalf D, Voss AK, Thomas T. MOZ (KAT6A) is essential for the maintenance of classically defined adult hematopoietic stem cells. Blood. PMID 27663673 DOI: 10.1182/Blood-2015-10-676072  0.388
2015 Lee SC, Miller S, Hyland C, Kauppi M, Lebois M, Di Rago L, Metcalf D, Kinkel SA, Josefsson EC, Blewitt ME, Majewski IJ, Alexander WS. Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis. Blood. 126: 167-75. PMID 26036803 DOI: 10.1182/Blood-2014-12-615898  0.33
2015 Ng AP, Hu Y, Metcalf D, Hyland CD, Ierino H, Phipson B, Wu D, Baldwin TM, Kauppi M, Kiu H, Di Rago L, Hilton DJ, Smyth GK, Alexander WS. Early lineage priming by trisomy of erg leads to myeloproliferation in a down syndrome model. Plos Genetics. 11: e1005211. PMID 25973911 DOI: 10.1371/Journal.Pgen.1005211  0.354
2014 Kedzierski L, Linossi EM, Kolesnik TB, Day EB, Bird NL, Kile BT, Belz GT, Metcalf D, Nicola NA, Kedzierska K, Nicholson SE. Suppressor of cytokine signaling 4 (SOCS4) protects against severe cytokine storm and enhances viral clearance during influenza infection. Plos Pathogens. 10: e1004134. PMID 24809749 DOI: 10.1371/Journal.Ppat.1004134  0.307
2014 van Nieuwenhuijze AE, Coghill E, Gray D, Prato S, Metcalf D, Alexander WS, Wicks IP. Transgenic expression of GM-CSF in T cells causes disseminated histiocytosis. The American Journal of Pathology. 184: 184-99. PMID 24183847 DOI: 10.1016/j.ajpath.2013.09.014  0.347
2014 Wang H, Yan M, Sun J, Jain S, Yoshimi R, Abolfath SM, Ozato K, Coleman WG, Ng AP, Metcalf D, DiRago L, Nutt SL, Morse HC. Correction: A Reporter Mouse Reveals Lineage-Specific and Heterogeneous Expression of IRF8 during Lymphoid and Myeloid Cell Differentiation The Journal of Immunology. 193: 4749-4749. DOI: 10.4049/Jimmunol.1490036  0.388
2013 Metcalf D. The colony-stimulating factors and cancer. Cancer Immunology Research. 1: 351-6. PMID 24524092 DOI: 10.1158/2326-6066.Cir-13-0151  0.411
2013 Metcalf D, Glaser SP, Xu Z, Di Rago L, Mifsud S. Reversible growth factor dependency and autonomy during murine myelomonocytic leukemia induced by oncogenes. Proceedings of the National Academy of Sciences of the United States of America. 110: 17029-34. PMID 24082086 DOI: 10.1073/pnas.1317055110  0.333
2013 Metcalf D, Ng AP, Baldwin TM, Di Rago L, Mifsud S. Concordant mast cell and basophil production by individual hematopoietic blast colony-forming cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 9031-5. PMID 23671076 DOI: 10.1073/pnas.1307711110  0.354
2012 Carmichael CL, Metcalf D, Henley KJ, Kruse EA, Di Rago L, Mifsud S, Alexander WS, Kile BT. Hematopoietic overexpression of the transcription factor Erg induces lymphoid and erythro-megakaryocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America. 109: 15437-42. PMID 22936051 DOI: 10.1073/pnas.1213454109  0.354
2012 Ng AP, Kauppi M, Metcalf D, Di Rago L, Hyland CD, Alexander WS. Characterization of thrombopoietin (TPO)-responsive progenitor cells in adult mouse bone marrow with in vivo megakaryocyte and erythroid potential. Proceedings of the National Academy of Sciences of the United States of America. 109: 2364-9. PMID 22308484 DOI: 10.1073/Pnas.1121385109  0.347
2012 Josefsson EC, Burnett DL, Debrincat MA, Henley KJ, Lane RM, Lebois M, O'Reilly LA, Pellegrini M, Preston SP, Croker BA, Metcalf D, Strasser A, Kile BT. Platelet Production Occurs Independently of Both the Intrinsic and Extrinsic Apoptosis Pathways Blood. 120: 389-389. DOI: 10.1182/Blood.V120.21.389.389  0.315
2012 McKenzie MD, Cimmino L, Hu Y, Rago LD, Mifsud S, Metcalf D, Smyth GK, Dickins R. Mechanisms of Tumor Suppression by the Hematopoietic Transcription Factor PU.1. Blood. 120: 2432-2432. DOI: 10.1182/Blood.V120.21.2432.2432  0.431
2012 Carmichael CL, Metcalf D, Henley KJ, Kruse EA, Rago LD, Mifsud S, Tang JZ, Alexander WS, Kile BT. Hematopoietic Overexpression of the ETS Family Transcription Factor Erg, or the Oncogenic Fusion Protein TLS-ERG, Induces Erythro-Megakaryocytic Leukemia Blood. 120: 1283-1283. DOI: 10.1182/Blood.V120.21.1283.1283  0.453
2012 Masters SL, Gerlic M, Metcalf D, Preston SP, Pellegrini M, O'Donnell JA, McArthur K, Baldwin TM, Chevrier S, Nowell CJ, Cengia LH, Henley KJ, Collinge JE, Kastner DL, Feigenbaum L, et al. Activation of the NLRP1 Inflammasome Induces the Pyroptotic Death of Hematopoietic Progenitor Cells Blood. 120: 1213-1213. DOI: 10.1182/Blood.V120.21.1213.1213  0.383
2011 Croker BA, O'Donnell JA, Nowell CJ, Metcalf D, Dewson G, Campbell KJ, Rogers KL, Hu Y, Smyth GK, Zhang JG, White M, Lackovic K, Cengia LH, O'Reilly LA, Bouillet P, et al. Fas-mediated neutrophil apoptosis is accelerated by Bid, Bak, and Bax and inhibited by Bcl-2 and Mcl-1. Proceedings of the National Academy of Sciences of the United States of America. 108: 13135-40. PMID 21768356 DOI: 10.1073/Pnas.1110358108  0.301
2011 Ng AP, Loughran SJ, Metcalf D, Hyland CD, de Graaf CA, Hu Y, Smyth GK, Hilton DJ, Kile BT, Alexander WS. Erg is required for self-renewal of hematopoietic stem cells during stress hematopoiesis in mice. Blood. 118: 2454-61. PMID 21673349 DOI: 10.1182/blood-2011-03-344739  0.301
2010 de Graaf CA, Kauppi M, Baldwin T, Hyland CD, Metcalf D, Willson TA, Carpinelli MR, Smyth GK, Alexander WS, Hilton DJ. Regulation of hematopoietic stem cells by their mature progeny. Proceedings of the National Academy of Sciences of the United States of America. 107: 21689-94. PMID 21115812 DOI: 10.1073/Pnas.1016166108  0.423
2010 Stevenson WS, Hyland CD, Zhang JG, Morgan PO, Willson TA, Gill A, Hilton AA, Viney EM, Bahlo M, Masters SL, Hennebry S, Richardson SJ, Nicola NA, Metcalf D, Hilton DJ, et al. Deficiency of 5-hydroxyisourate hydrolase causes hepatomegaly and hepatocellular carcinoma in mice. Proceedings of the National Academy of Sciences of the United States of America. 107: 16625-30. PMID 20823251 DOI: 10.1073/Pnas.1010390107  0.304
2010 Metcalf D, Ng A, Mifsud S, Di Rago L. Multipotential hematopoietic blast colony-forming cells exhibit delays in self-generation and lineage commitment. Proceedings of the National Academy of Sciences of the United States of America. 107: 16257-61. PMID 20805490 DOI: 10.1073/Pnas.1011881107  0.389
2010 Campbell KJ, Bath ML, Turner ML, Vandenberg CJ, Bouillet P, Metcalf D, Scott CL, Cory S. Elevated Mcl-1 perturbs lymphopoiesis, promotes transformation of hematopoietic stem/progenitor cells, and enhances drug resistance. Blood. 116: 3197-207. PMID 20631380 DOI: 10.1182/Blood-2010-04-281071  0.415
2010 Metcalf D. The colony-stimulating factors and cancer. Nature Reviews. Cancer. 10: 425-34. PMID 20495576 DOI: 10.1038/Nrc2843  0.419
2010 Murphy JM, Metcalf D, Young IG, Hilton DJ. A convenient method for preparation of an engineered mouse interleukin-3 analog with high solubility and wild-type bioactivity. Growth Factors (Chur, Switzerland). 28: 104-10. PMID 19961363 DOI: 10.3109/08977190903443048  0.327
2010 Josefsson EC, James C, Henley KJ, Debrincat MA, Rogers KL, Dowling MR, White MJ, Kruse EA, Ellis S, Nurden P, Vandenberg CJ, Mason KD, Lorraine AO, Metcalf D, Roberts AW, et al. Megakaryocytes Possess a Functional Intrinsic Apoptosis Pathway That Must Be Restrained In Order to Survive and Produce Platelets Blood. 116: 550-550. DOI: 10.1182/Blood.V116.21.550.550  0.311
2009 Metcalf D, Ng AP, Loughran SJ, Phipson B, Smyth GK, Di Rago L, Mifsud S. Murine hematopoietic blast colony-forming cells and their progeny have distinctive membrane marker profiles. Proceedings of the National Academy of Sciences of the United States of America. 106: 19102-7. PMID 19855004 DOI: 10.1073/Pnas.0910354106  0.446
2009 Kruse EA, Loughran SJ, Baldwin TM, Josefsson EC, Ellis S, Watson DK, Nurden P, Metcalf D, Hilton DJ, Alexander WS, Kile BT. Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage. Proceedings of the National Academy of Sciences of the United States of America. 106: 13814-9. PMID 19666492 DOI: 10.1073/Pnas.0906556106  0.401
2009 D'Costa K, Emslie D, Metcalf D, Smyth GK, Karnowski A, Kallies A, Nutt SL, Corcoran LM. Blimp1 is limiting for transformation in a mouse plasmacytoma model. Blood. 113: 5911-9. PMID 19329782 DOI: 10.1182/Blood-2008-08-172866  0.374
2009 Verhagen AM, Wallace ME, Goradia A, Jones SA, Croom HA, Metcalf D, Collinge JE, Maxwell MJ, Hibbs ML, Alexander WS, Hilton DJ, Kile BT, Starr R. A kinase-dead allele of Lyn attenuates autoimmune disease normally associated with Lyn deficiency. Journal of Immunology (Baltimore, Md. : 1950). 182: 2020-9. PMID 19201855 DOI: 10.4049/Jimmunol.0803127  0.381
2009 Carmichael CL, Majewski IJ, Alexander WS, Metcalf D, Hilton DJ, Hewitt CA, Scott HS. Hematopoietic defects in the Ts1Cje mouse model of Down syndrome. Blood. 113: 1929-37. PMID 19109561 DOI: 10.1182/Blood-2008-06-161422  0.369
2009 Metcalf D. Regulatory mechanisms controlling hematopoiesis: principles and problems. Stem Cells. 16: 3-11. PMID 11012144 DOI: 10.1002/Stem.5530160804  0.422
2009 Morstyn G, Metcalf D, Burgess A, Fabre JW. Surface antigens on normal and leukaemic human cells detected by monoclonal antibodies. Scandinavian Journal of Haematology. 26: 19-30. PMID 6162194 DOI: 10.1111/J.1600-0609.1981.Tb01619.X  0.347
2009 Cornish AL, Eyles JL, Murphy J, Drake SF, Metcalf D, Roberts AW, Tarlinton DM, Wicks IP. Administered G-CSF boosts low affinity antibody production during T cell-dependent responses Cytokine. 48: 102. DOI: 10.1016/J.Cyto.2009.07.428  0.324
2008 Eyles JL, Hickey MJ, Norman MU, Croker BA, Roberts AW, Drake SF, James WG, Metcalf D, Campbell IK, Wicks IP. A key role for G-CSF-induced neutrophil production and trafficking during inflammatory arthritis. Blood. 112: 5193-201. PMID 18824600 DOI: 10.1182/Blood-2008-02-139535  0.344
2008 Kauppi M, Murphy JM, de Graaf CA, Hyland CD, Greig KT, Metcalf D, Hilton AA, Nicola NA, Kile BT, Hilton DJ, Alexander WS. Point mutation in the gene encoding p300 suppresses thrombocytopenia in Mpl-/- mice. Blood. 112: 3148-53. PMID 18684867 DOI: 10.1182/Blood-2007-10-119677  0.336
2008 Loughran SJ, Kruse EA, Hacking DF, de Graaf CA, Hyland CD, Willson TA, Henley KJ, Ellis S, Voss AK, Metcalf D, Hilton DJ, Alexander WS, Kile BT. The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells. Nature Immunology. 9: 810-9. PMID 18500345 DOI: 10.1038/Ni.1617  0.365
2008 Majewski IJ, Blewitt ME, de Graaf CA, McManus EJ, Bahlo M, Hilton AA, Hyland CD, Smyth GK, Corbin JE, Metcalf D, Alexander WS, Hilton DJ. Polycomb repressive complex 2 (PRC2) restricts hematopoietic stem cell activity. Plos Biology. 6: e93. PMID 18416604 DOI: 10.1371/Journal.Pbio.0060093  0.4
2008 Croker BA, Mielke LA, Wormald S, Metcalf D, Kiu H, Alexander WS, Hilton DJ, Roberts AW. Socs3 maintains the specificity of biological responses to cytokine signals during granulocyte and macrophage differentiation. Experimental Hematology. 36: 786-98. PMID 18400361 DOI: 10.1016/J.Exphem.2008.02.008  0.449
2008 Emslie D, D'Costa K, Hasbold J, Metcalf D, Takatsu K, Hodgkin PO, Corcoran LM. Oct2 enhances antibody-secreting cell differentiation through regulation of IL-5 receptor alpha chain expression on activated B cells. The Journal of Experimental Medicine. 205: 409-21. PMID 18250192 DOI: 10.1084/Jem.20072049  0.404
2008 Metcalf D. Hematopoietic cytokines. Blood. 111: 485-91. PMID 18182579 DOI: 10.1182/blood-2007-03-079681  0.361
2008 Metcalf D. AGM: maternity ward or finishing school? Blood. 111: 3305-3306. DOI: 10.1182/Blood-2007-11-124412  0.324
2007 Metcalf D, Glaser S, Mifsud S, Di Rago L, Robb L. The preleukemic state of mice reconstituted with Mixl1-transduced marrow cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 20013-8. PMID 18056627 DOI: 10.1073/Pnas.0710339104  0.464
2007 Tucker E, O'Donnell K, Fuchsberger M, Hilton AA, Metcalf D, Greig K, Sims NA, Quinn JM, Alexander WS, Hilton DJ, Kile BT, Tarlinton DM, Starr R. A novel mutation in the Nfkb2 gene generates an NF-kappa B2 "super repressor". Journal of Immunology (Baltimore, Md. : 1950). 179: 7514-22. PMID 18025196 DOI: 10.4049/Jimmunol.179.11.7514  0.344
2007 Metcalf D, Majewski I, Mifsud S, Di Rago L, Alexander WS. Clonogenic mast cell progenitors and their excess numbers in chimeric BALB/c mice with inactivated GATA-1. Proceedings of the National Academy of Sciences of the United States of America. 104: 18642-7. PMID 18000035 DOI: 10.1073/Pnas.0709625104  0.472
2007 Metcalf D. On hematopoietic stem cell fate. Immunity. 26: 669-73. PMID 17582339 DOI: 10.1016/J.Immuni.2007.05.012  0.368
2007 Boyle K, Egan P, Rakar S, Willson TA, Wicks IP, Metcalf D, Hilton DJ, Nicola NA, Alexander WS, Roberts AW, Robb L. The SOCS box of suppressor of cytokine signaling-3 contributes to the control of G-CSF responsiveness in vivo. Blood. 110: 1466-74. PMID 17510322 DOI: 10.1182/Blood-2007-03-079178  0.401
2006 Alexander WS, Viney EM, Zhang JG, Metcalf D, Kauppi M, Hyland CD, Carpinelli MR, Stevenson W, Croker BA, Hilton AA, Ellis S, Selan C, Nandurkar HH, Goodnow CC, Kile BT, et al. Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene. Proceedings of the National Academy of Sciences of the United States of America. 103: 16442-7. PMID 17062753 DOI: 10.1073/Pnas.0607872103  0.319
2006 Glaser S, Metcalf D, Wu L, Hart AH, DiRago L, Mifsud S, D'Amico A, Dagger S, Campo C, Chan AC, Izon DJ, Robb L. Enforced expression of the homeobox gene Mixl1 impairs hematopoietic differentiation and results in acute myeloid leukemia. Proceedings of the National Academy of Sciences of the United States of America. 103: 16460-5. PMID 17060613 DOI: 10.1073/Pnas.0607776103  0.398
2006 Eyles JL, Roberts AW, Metcalf D, Wicks IP. Granulocyte colony-stimulating factor and neutrophils--forgotten mediators of inflammatory disease. Nature Clinical Practice. Rheumatology. 2: 500-10. PMID 16951705 DOI: 10.1038/Ncprheum0291  0.38
2006 Naik SH, Metcalf D, van Nieuwenhuijze A, Wicks I, Wu L, O'Keeffe M, Shortman K. Intrasplenic steady-state dendritic cell precursors that are distinct from monocytes. Nature Immunology. 7: 663-71. PMID 16680143 DOI: 10.1038/Ni1340  0.311
2006 Thomas T, Corcoran LM, Gugasyan R, Dixon MP, Brodnicki T, Nutt SL, Metcalf D, Voss AK. Monocytic leukemia zinc finger protein is essential for the development of long-term reconstituting hematopoietic stem cells. Genes & Development. 20: 1175-86. PMID 16651658 DOI: 10.1101/Gad.1382606  0.425
2006 Kallies A, Hawkins ED, Belz GT, Metcalf D, Hommel M, Corcoran LM, Hodgkin PD, Nutt SL. Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance. Nature Immunology. 7: 466-74. PMID 16565720 DOI: 10.1038/Ni1321  0.381
2006 Smith DP, Bath ML, Metcalf D, Harris AW, Cory S. MYC levels govern hematopoietic tumor type and latency in transgenic mice. Blood. 108: 653-61. PMID 16537801 DOI: 10.1182/Blood-2006-01-0172  0.384
2006 Metcalf D, Dakic A, Mifsud S, Di Rago L, Wu L, Nutt S. Inactivation of PU.1 in adult mice leads to the development of myeloid leukemia. Proceedings of the National Academy of Sciences of the United States of America. 103: 1486-91. PMID 16432184 DOI: 10.1073/Pnas.0510616103  0.447
2006 Fenner JE, Starr R, Cornish AL, Zhang JG, Metcalf D, Schreiber RD, Sheehan K, Hilton DJ, Alexander WS, Hertzog PJ. Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activity. Nature Immunology. 7: 33-9. PMID 16311601 DOI: 10.1038/Ni1287  0.315
2006 Metcalf D, Laâbi Y. Lineage commitment and maturation induction in normal and leukemic preprogenitor cells. Annals of the New York Academy of Sciences. 938: 278-292. PMID 11458517 DOI: 10.1111/J.1749-6632.2001.Tb03597.X  0.429
2006 Mason KD, Carpinelli MR, Collinge JE, Hilton AA, Fletcher JI, Roberts AW, Metcalf D, Huang DCS, Kile BT. The Bcl-2 Protein Family Is Essential for Platelet Survival In Vivo. Blood. 108: 697-697. DOI: 10.1182/Blood.V108.11.697.697  0.31
2006 Roberts AW, Mielke L, Wormald S, Kiu H, Croker BA, Hilton DJ, Metcalf D, Alexander WS. Suppressor of Cytokine Signaling-3 (SOCS3) Selectively Modulates Progenitor Cell Proliferation and Differentiation Induced by G-CSF and IL-6, and the Synergy between SCF and IL-6. Blood. 108: 631-631. DOI: 10.1182/Blood.V108.11.631.631  0.39
2005 Robb L, Boyle K, Rakar S, Hartley L, Lochland J, Roberts AW, Alexander WS, Metcalf D. Genetic reduction of embryonic leukemia-inhibitory factor production rescues placentation in SOCS3-null embryos but does not prevent inflammatory disease. Proceedings of the National Academy of Sciences of the United States of America. 102: 16333-8. PMID 16258063 DOI: 10.1073/Pnas.0508023102  0.407
2005 Pellegrini M, Bath S, Marsden VS, Huang DC, Metcalf D, Harris AW, Strasser A. FADD and caspase-8 are required for cytokine-induced proliferation of hemopoietic progenitor cells. Blood. 106: 1581-9. PMID 15905188 DOI: 10.1182/Blood-2005-01-0284  0.429
2005 Chong MM, Metcalf D, Jamieson E, Alexander WS, Kay TW. Suppressor of cytokine signaling-1 in T cells and macrophages is critical for preventing lethal inflammation. Blood. 106: 1668-75. PMID 15899915 DOI: 10.1182/Blood-2004-08-3049  0.388
2005 Dakic A, Metcalf D, Di Rago L, Mifsud S, Wu L, Nutt SL. PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis. The Journal of Experimental Medicine. 201: 1487-502. PMID 15867096 DOI: 10.1084/Jem.20050075  0.444
2005 Nicholson SE, Metcalf D, Sprigg NS, Columbus R, Walker F, Silva A, Cary D, Willson TA, Zhang JG, Hilton DJ, Alexander WS, Nicola NA. Suppressor of cytokine signaling (SOCS)-5 is a potential negative regulator of epidermal growth factor signaling. Proceedings of the National Academy of Sciences of the United States of America. 102: 2328-33. PMID 15695332 DOI: 10.1073/Pnas.0409675102  0.326
2005 Greenhalgh CJ, Rico-Bautista E, Lorentzon M, Thaus AL, Morgan PO, Willson TA, Zervoudakis P, Metcalf D, Street I, Nicola NA, Nash AD, Fabri LJ, Norstedt G, Ohlsson C, Flores-Morales A, et al. SOCS2 negatively regulates growth hormone action in vitro and in vivo. The Journal of Clinical Investigation. 115: 397-406. PMID 15690087 DOI: 10.1172/Jci22710  0.322
2005 Metcalf D, Carpinelli MR, Hyland C, Mifsud S, Dirago L, Nicola NA, Hilton DJ, Alexander WS. Anomalous megakaryocytopoiesis in mice with mutations in the c-Myb gene. Blood. 105: 3480-7. PMID 15665109 DOI: 10.1182/Blood-2004-12-4806  0.444
2005 Nutt SL, Metcalf D, D'Amico A, Polli M, Wu L. Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors. The Journal of Experimental Medicine. 201: 221-31. PMID 15657291 DOI: 10.1084/Jem.20041535  0.397
2005 Metcalf D, Mifsud S, Di Rago L. Murine megakaryocyte progenitor cells and their susceptibility to suppression by G-CSF. Stem Cells (Dayton, Ohio). 23: 55-62. PMID 15625122 DOI: 10.1634/Stemcells.2004-0164  0.475
2005 Stevenson WS, Metcalf D, Alexander WS, Hilton DJ, Roberts AW. A Genetic Mutation on Murine Chromosome 7 Causes Thrombocytosis Associated with Thrombopoietin Excess - A Model of Jak2V617F Negative Idiopathic Thrombocytosis. Blood. 106: 3525-3525. DOI: 10.1182/Blood.V106.11.3525.3525  0.317
2004 Krebs DL, Metcalf D, Merson TD, Voss AK, Thomas T, Zhang JG, Rakar S, O'bryan MK, Willson TA, Viney EM, Mielke LA, Nicola NA, Hilton DJ, Alexander WS. Development of hydrocephalus in mice lacking SOCS7. Proceedings of the National Academy of Sciences of the United States of America. 101: 15446-51. PMID 15494444 DOI: 10.1073/Pnas.0406870101  0.343
2004 Lawlor KE, Campbell IK, Metcalf D, O'Donnell K, van Nieuwenhuijze A, Roberts AW, Wicks IP. Critical role for granulocyte colony-stimulating factor in inflammatory arthritis. Proceedings of the National Academy of Sciences of the United States of America. 101: 11398-403. PMID 15272075 DOI: 10.1073/Pnas.0404328101  0.362
2004 Brender C, Columbus R, Metcalf D, Handman E, Starr R, Huntington N, Tarlinton D, Ødum N, Nicholson SE, Nicola NA, Hilton DJ, Alexander WS. SOCS5 is expressed in primary B and T lymphoid cells but is dispensable for lymphocyte production and function. Molecular and Cellular Biology. 24: 6094-103. PMID 15199163 DOI: 10.1128/Mcb.24.13.6094-6103.2004  0.41
2004 Croker BA, Metcalf D, Robb L, Wei W, Mifsud S, DiRago L, Cluse LA, Sutherland KD, Hartley L, Williams E, Zhang JG, Hilton DJ, Nicola NA, Alexander WS, Roberts AW. SOCS3 is a critical physiological negative regulator of G-CSF signaling and emergency granulopoiesis. Immunity. 20: 153-65. PMID 14975238 DOI: 10.1016/S1074-7613(04)00022-6  0.425
2004 Fairlie WD, Uboldi AD, McCoubrie JE, Wang CC, Lee EF, Yao S, De Souza DP, Mifsud S, Metcalf D, Nicola NA, Norton RS, Baca M. Affinity maturation of leukemia inhibitory factor and conversion to potent antagonists of signaling. The Journal of Biological Chemistry. 279: 2125-34. PMID 14585833 DOI: 10.1074/Jbc.M310103200  0.321
2004 Roberts AW, Croker BA, Alexander W, Metcalf D. Aberrant G-CSF- and IL-6-Induced Proliferation and Differentiation in Suppressor of Cytokine Signaling-3 (SOCS3)-Deficient Progenitor Cells. Blood. 104: 821-821. DOI: 10.1182/Blood.V104.11.821.821  0.455
2004 Stevenson WS, Metcalf D, Hilton DJ, Roberts AW, Alexander WS. ENU Mutagenesis Screen Identifies a Novel Regulator of Platelet Production. Blood. 104: 518-518. DOI: 10.1182/Blood.V104.11.518.518  0.326
2003 Metcalf D, Mifsud S, Di Rago L, Alexander WS. The lethal effects of transplantation of Socs1-/- bone marrow cells into irradiated adult syngeneic recipients. Proceedings of the National Academy of Sciences of the United States of America. 100: 8436-41. PMID 12821775 DOI: 10.1073/Pnas.1032925100  0.401
2003 Croker BA, Krebs DL, Zhang JG, Wormald S, Willson TA, Stanley EG, Robb L, Greenhalgh CJ, Förster I, Clausen BE, Nicola NA, Metcalf D, Hilton DJ, Roberts AW, Alexander WS. SOCS3 negatively regulates IL-6 signaling in vivo. Nature Immunology. 4: 540-5. PMID 12754505 DOI: 10.1038/Ni931  0.331
2003 Tarlinton D, Light A, Metcalf D, Harvey RP, Robb L. Architectural Defects in the Spleens of Nkx2-3-Deficient Mice Are Intrinsic and Associated with Defects in Both B Cell Maturation and T Cell-Dependent Immune Responses Journal of Immunology. 170: 4002-4010. PMID 12682228 DOI: 10.4049/Jimmunol.170.8.4002  0.42
2003 Hall MA, Curtis DJ, Metcalf D, Elefanty AG, Sourris K, Robb L, Gothert JR, Jane SM, Begley CG. The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12. Proceedings of the National Academy of Sciences of the United States of America. 100: 992-7. PMID 12552125 DOI: 10.1073/Pnas.0237324100  0.445
2003 Metcalf D, Rago LD, Mifsud S. Crowding-dependent production of colony-stimulating factors by cultured syngeneic or allogeneic hematopoietic cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 1244-1249. PMID 12552101 DOI: 10.1073/Pnas.252756999  0.428
2003 Metcalf D. The unsolved enigmas of leukemia inhibitory factor. Stem Cells. 21: 5-14. PMID 12529546 DOI: 10.1634/Stemcells.21-1-5  0.377
2003 Cornish AL, Davey GM, Metcalf D, Purton JF, Corbin JE, Greenhalgh CJ, Darwiche R, Wu L, Nicola NA, Godfrey DI, Heath WR, Hilton DJ, Alexander WS, Starr R. Suppressor of cytokine signaling-1 has IFN-gamma-independent actions in T cell homeostasis. Journal of Immunology (Baltimore, Md. : 1950). 170: 878-86. PMID 12517953 DOI: 10.4049/Jimmunol.170.2.878  0.378
2002 Metcalf D, Rago LD, Mifsud S. Synergistic and inhibitory interactions in the in vitro control of murine megakaryocyte colony formation Stem Cells. 20: 552-560. PMID 12456963 DOI: 10.1002/Stem.200552  0.415
2002 Metcalf D, Mifsud S, Rago LD. Stem Cell Factor Can Stimulate the Formation of Eosinophils by Two Types of Murine Eosinophil Progenitor Cells Stem Cells. 20: 460-469. PMID 12351816 DOI: 10.1634/Stemcells.20-5-460  0.423
2002 Greenhalgh CJ, Metcalf D, Thaus AL, Corbin JE, Uren R, Morgan PO, Fabri LJ, Zhang JG, Martin HM, Willson TA, Billestrup N, Nicola NA, Baca M, Alexander WS, Hilton DJ. Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling. The Journal of Biological Chemistry. 277: 40181-4. PMID 12208853 DOI: 10.1074/Jbc.C200450200  0.337
2002 Tarrant JM, Groom J, Metcalf D, Li R, Borobokas B, Wright MD, Tarlinton D, Robb L. The absence of Tssc6, a member of the tetraspanin superfamily, does not affect lymphoid development but enhances in vitro T-cell proliferative responses. Molecular and Cellular Biology. 22: 5006-18. PMID 12077330 DOI: 10.1128/Mcb.22.14.5006-5018.2002  0.433
2002 Krebs DL, Uren RT, Metcalf D, Rakar S, Zhang JG, Starr R, De Souza DP, Hanzinikolas K, Eyles J, Connolly LM, Simpson RJ, Nicola NA, Nicholson SE, Baca M, Hilton DJ, et al. SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation. Molecular and Cellular Biology. 22: 4567-78. PMID 12052866 DOI: 10.1128/Mcb.22.13.4567-4578.2002  0.307
2002 Greenhalgh CJ, Bertolino P, Asa SL, Metcalf D, Corbin JE, Adams TE, Davey HW, Nicola NA, Hilton DJ, Alexander WS. Growth enhancement in suppressor of cytokine signaling 2 (SOCS-2)-deficient mice is dependent on signal transducer and activator of transcription 5b (STAT5b). Molecular Endocrinology (Baltimore, Md.). 16: 1394-406. PMID 12040024 DOI: 10.1210/Mend.16.6.0845  0.337
2002 Metcalf D, Mifsud S, Di Rago L, Nicola NA, Hilton DJ, Alexander WS. Polycystic kidneys and chronic inflammatory lesions are the delayed consequences of loss of the suppressor of cytokine signaling-1 (SOCS-1). Proceedings of the National Academy of Sciences of the United States of America. 99: 943-8. PMID 11782537 DOI: 10.1073/Pnas.022628499  0.311
2001 Zhang JG, Metcalf D, Rakar S, Asimakis M, Greenhalgh CJ, Willson TA, Starr R, Nicholson SE, Carter W, Alexander WS, Hilton DJ, Nicola NA. The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo. Proceedings of the National Academy of Sciences of the United States of America. 98: 13261-5. PMID 11606785 DOI: 10.1073/Pnas.231486498  0.337
2001 Metcalf D, Alexander WS, Ryan PJ, Mifsud S, Di Rago L. Production of colony-stimulating factors and IL-5 by organs from three types of mice with inflammatory disease due to loss of the suppressor of cytokine signaling-1. Journal of Immunology (Baltimore, Md. : 1950). 167: 4661-7. PMID 11591796 DOI: 10.4049/Jimmunol.167.8.4661  0.362
2001 Bullen DV, Darwiche R, Metcalf D, Handman E, Alexander WS. Neutralization of interferon-gamma in neonatal SOCS1-/- mice prevents fatty degeneration of the liver but not subsequent fatal inflammatory disease. Immunology. 104: 92-8. PMID 11576226 DOI: 10.1046/J.1365-2567.2001.01294.X  0.332
2001 Roberts AW, Robb L, Rakar S, Hartley L, Cluse L, Nicola NA, Metcalf D, Hilton DJ, Alexander WS. Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3. Proceedings of the National Academy of Sciences of the United States of America. 98: 9324-9. PMID 11481489 DOI: 10.1073/Pnas.161271798  0.359
2000 Metcalf D, Di Rago L, Mifsud S, Hartley L, Alexander WS. The development of fatal myocarditis and polymyositis in mice heterozygous for IFN-gamma and lacking the SOCS-1 gene. Proceedings of the National Academy of Sciences of the United States of America. 97: 9174-9. PMID 10908669 DOI: 10.1073/Pnas.160255197  0.306
2000 Metcalf D, Greenhalgh CJ, Viney E, Willson TA, Starr R, Nicola NA, Hilton DJ, Alexander WS. Gigantism in mice lacking suppressor of cytokine signalling-2. Nature. 405: 1069-73. PMID 10890450 DOI: 10.1038/35016611  0.344
2000 Curtis DJ, Metcalf D, Alexander B, Begley CG. Leukemic cells from murine myeloid leukemia display an intrinsic ability for autonomous proliferation. Experimental Hematology. 28: 36-45. PMID 10658675 DOI: 10.1016/S0301-472X(99)00123-X  0.428
2000 Hasegawa M, Baldwin TM, Metcalf D, Foote SJ. Progenitor cell mobilization by granulocyte colony-stimulating factor controlled by loci on chromosomes 2 and 11. Blood. 95: 1872-1874. DOI: 10.1182/Blood.V95.5.1872.005K26_1872_1874  0.414
2000 Gainsford T, Nandurkar H, Metcalf D, Robb L, Begley CG, Alexander WS. The residual megakaryocyte and platelet production in c-Mpl–deficient mice is not dependent on the actions of interleukin-6, interleukin-11, or leukemia inhibitory factor Blood. 95: 528-534. DOI: 10.1182/Blood.V95.2.528  0.354
1999 Metcalf D. The SOCS-1 story. Experimental Hematology. 27: 1715-1723. PMID 10641589 DOI: 10.1016/S0301-472X(99)00120-4  0.334
1999 Ogilvy S, Metcalf D, Print CG, Bath ML, Harris AW, Adams JM. Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival. Proceedings of the National Academy of Sciences of the United States of America. 96: 14943-8. PMID 10611317 DOI: 10.1073/Pnas.96.26.14943  0.467
1999 Bouillet P, Metcalf D, Huang DC, Tarlinton DM, Kay TW, Köntgen F, Adams JM, Strasser A. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science (New York, N.Y.). 286: 1735-8. PMID 10576740 DOI: 10.1126/Science.286.5445.1735  0.355
1999 Alexander WS, Starr R, Metcalf D, Nicholson SE, Farley A, Elefanty AG, Brysha M, Kile BT, Richardson R, Baca M, Zhang JG, Willson TA, Viney EM, Sprigg NS, Rakar S, et al. Suppressors of cytokine signaling (SOCS): negative regulators of signal transduction. Journal of Leukocyte Biology. 66: 588-92. PMID 10534114 DOI: 10.1002/Jlb.66.4.588  0.356
1999 Metcalf D. Stem cells, pre-progenitor cells and lineage-committed cells: are our dogmas correct? Annals of the New York Academy of Sciences. 872: 289-304. PMID 10372131 DOI: 10.1111/J.1749-6632.1999.Tb08473.X  0.397
1999 Nicholson SE, Willson TA, Farley A, Starr R, Zhang JG, Baca M, Alexander WS, Metcalf D, Hilton DJ, Nicola NA. Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction Embo Journal. 18: 375-385. PMID 9889194 DOI: 10.1093/Emboj/18.2.375  0.308
1999 Ogilvy S, Metcalf D, Gibson L, Bath ML, Harris AW, Adams JM. Promoter elements of vav drive transgene expression in vivo throughout the hematopoietic compartment. Blood. 94: 1855-1863. DOI: 10.1182/Blood.V94.6.1855.418K33_1855_1863  0.372
1999 Metcalf D, Nicola NA, Mifsud S, Rago LD. Receptor clearance obscures the magnitude of granulocyte-macrophage colony-stimulating factor responses in mice to endotoxin or local infections. Blood. 93: 1579-1585. DOI: 10.1182/Blood.V93.5.1579.405K01_1579_1585  0.402
1998 Zhang Y, Willson T, Metcalf D, Cary D, Hilton DJ, Clark R, Nicola NA. The box-1 region of the leukemia inhibitory factor receptor α-chain cytoplasmic domain is sufficient for hemopoietic cell proliferation and differentiation Journal of Biological Chemistry. 273: 34370-34383. PMID 9852103 DOI: 10.1074/Jbc.273.51.34370  0.407
1998 Metcalf D. Cell-Cell Signalling In The Regulation Of Blood Cell Formation And Function Immunology and Cell Biology. 76: 441-447. PMID 9797465 DOI: 10.1046/J.1440-1711.1998.00761.X  0.453
1998 Print CG, Loveland KL, Gibson L, Meehan T, Stylianou A, Wreford N, de Kretser D, Metcalf D, Köntgen F, Adams JM, Cory S. Apoptosis regulator bcl-w is essential for spermatogenesis but appears otherwise redundant. Proceedings of the National Academy of Sciences of the United States of America. 95: 12424-31. PMID 9770502 DOI: 10.1073/Pnas.95.21.12424  0.336
1998 Metcalf D. Lineage commitment in the progeny of murine hematopoietic preprogenitor cells: Influence of thrombopoietin and interleukin 5 Proceedings of the National Academy of Sciences of the United States of America. 95: 6408-6412. PMID 9600979 DOI: 10.1073/Pnas.95.11.6408  0.468
1998 Cambier N, Chopra R, Strasser A, Metcalf D, Elefanty AG. BCR-ABL activates pathways mediating cytokine independence and protection against apoptosis in murine hematopoietic cells in a dose-dependent manner Oncogene. 16: 335-348. PMID 9467959 DOI: 10.1038/Sj.Onc.1201490  0.342
1998 Kimura S, Roberts AW, Metcalf D, Alexander WS. Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin Proceedings of the National Academy of Sciences of the United States of America. 95: 1195-1200. PMID 9448308 DOI: 10.1073/Pnas.95.3.1195  0.444
1998 Metcalf D. Lineage Commitment and Maturation in Hematopoietic Cells: The Case for Extrinsic Regulation Blood. 92: 345-347. DOI: 10.1182/Blood.V92.2.345B.Con2_345_347  0.342
1997 Metcalf D. Murine hematopoietic stem cells committed to macrophage/dendritic cell formation: Stimulation by Flk2-ligand with enhancement by regulators using the gp130 receptor chain Proceedings of the National Academy of Sciences of the United States of America. 94: 11552-11556. PMID 9326647 DOI: 10.1073/Pnas.94.21.11552  0.475
1997 Starr R, Willson TA, Viney EM, Murray LJL, Rayner JR, Jenkins BJ, Gonda TJ, Alexander WS, Metcalf D, Nicola NA, Hilton DJ. A family of cytokine-inducible inhibitors of signalling Nature. 387: 917-921. PMID 9202125 DOI: 10.1038/43206  0.342
1997 Smith A, Metcalf D, Nicola NA. Cytoplasmic domains of the common β‐chain of the GM‐CSF/IL‐3/IL‐5 receptors that are required for inducing differentiation or clonal suppression in myeloid leukaemic cell lines The Embo Journal. 16: 451-464. PMID 9034328 DOI: 10.1093/Emboj/16.3.451  0.423
1997 Vremec D, Lieschke GJ, Dunn AR, Robb L, Metcalf D, Shortman K. The influence of granulocyte/macrophage colony-stimulating factor on dendritic cell levels in mouse lymphoid organs. European Journal of Immunology. 27: 40-4. PMID 9021996 DOI: 10.1002/Eji.1830270107  0.377
1997 Metcalf D. Another way to generate T cells Nature Medicine. 3: 18-19. PMID 8986729 DOI: 10.1038/Nm0197-18  0.301
1997 Roberts AW, Foote S, Alexander WS, Scott C, Robb L, Metcalf D. Genetic Influences Determining Progenitor Cell Mobilization and Leukocytosis Induced by Granulocyte Colony-Stimulating Factor Blood. 89: 2736-2744. DOI: 10.1182/Blood.V89.8.2736  0.46
1997 McKinstry WJ, Li C, Rasko JEJ, Nicola NA, Johnson GR, Metcalf D. Cytokine receptor expression on hematopoietic stem and progenitor cells. Blood. 89: 65-71. DOI: 10.1182/Blood.V89.1.65.65_65_71  0.446
1996 Alexander WS, Roberts AW, Maurer AB, Nicola NA, Dunn AR, Metcalf D. Studies of the c-Mpl thrombopoietin receptor through gene disruption and activation. Stem Cells (Dayton, Ohio). 14: 124-32. PMID 11012212 DOI: 10.1002/Stem.5530140716  0.423
1996 Gainsford T, Willson TA, Metcalf D, Handman E, Mcfarlane C, Ng A, Nicola NA, Alexander WS, Hilton DJ. Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells Proceedings of the National Academy of Sciences of the United States of America. 93: 14564-14568. PMID 8962092 DOI: 10.1073/Pnas.93.25.14564  0.418
1996 Gerondakis SD, Strasser A, Metcalf D, Grigoriadis G, Scheerlinck JY, Grumont RJ. Rel-deficient T cells exhibit defects in production of interleukin 3 and granulocyte-macrophage colony-stimulating factor Proceedings of the National Academy of Sciences of the United States of America. 93: 3405-3409. PMID 8622948 DOI: 10.1073/Pnas.93.8.3405  0.388
1996 Metcalf D. The cellular basis for enhancement interactions between stem cell factor and the colony stimulating factors Stem Cells. 11: 1-11. PMID 7691313 DOI: 10.1002/Stem.5530110803  0.477
1996 Alexander WS, Roberts AW, Nicola NA, Li R, Metcalf D. Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietic receptor c-Mpl Blood. 87: 2162-2170. DOI: 10.1182/Blood.V87.6.2162.Bloodjournal8762162  0.452
1996 Grigoriadis G, Zhan Y, Grumont RJ, Metcalf D, Handman E, Cheers C, Gerondakis SD. The Rel subunit of NF-kappaB-like transcription factors is a positive and negative regulator of macrophage gene expression: distinct roles for Rel in different macrophage populations. The Embo Journal. 15: 7099-7107. DOI: 10.1002/J.1460-2075.1996.Tb01101.X  0.396
1995 Waring PM, Presneill J, Maher DW, Layton JE, Cebon J, Waring LJ, Metcalf D. Differential alterations in plasma colony-stimulating factor concentrations in meningococcaemia. Clinical and Experimental Immunology. 102: 501-6. PMID 8536364 DOI: 10.1111/J.1365-2249.1995.Tb03844.X  0.309
1995 Waring PM, Waring LJ, Billington T, Metcalf D. Leukemia inhibitory factor protects against experimental lethal Escherichia coli septic shock in mice. Proceedings of the National Academy of Sciences of the United States of America. 92: 1337-1341. PMID 7877978 DOI: 10.1073/Pnas.92.5.1337  0.307
1995 Metcalf D, Lindeman GJ, Nicola NA. Analysis of hematopoiesis in max 41 transgenic mice that exhibit sustained elevations of blood granulocytes and monocytes Blood. 85: 2364-2370. DOI: 10.1182/Blood.V85.9.2364.Bloodjournal8592364  0.479
1994 Brown MA, Metcalf D, Gough NM. Leukaemia inhibitory factor and interleukin 6 are expressed at very low levels in the normal adult mouse and are induced by inflammation Cytokine. 6: 300-309. PMID 8054487 DOI: 10.1016/1043-4666(94)90027-2  0.318
1994 Metcalf D. Hemopoietic regulators and leukemia development: a personal retrospective. Advances in Cancer Research. 63: 41-91. PMID 8036990 DOI: 10.1016/S0065-230X(08)60398-X  0.383
1994 Metcalf D. Implications of the polyfunctionality of hemopoietic regulators Stem Cells. 12: 259-275. PMID 7696965 DOI: 10.1002/Stem.5530120722  0.35
1994 Metcalf D, Willson T, Rossner M, Lock P. Receptor insertion into factor-dependent murine cell lines to develop specific bioassays for murine G-CSF and M-CSF and human GM-CSF. Growth Factors (Chur, Switzerland). 11: 145-52. PMID 7531988 DOI: 10.3109/08977199409001056  0.372
1993 Waring P, Wall D, Dauer R, Parkin D, Metcalf D. The effects of leukaemia inhibitory factor on platelet function British Journal of Haematology. 83: 80-87. PMID 8435339 DOI: 10.1111/J.1365-2141.1993.Tb04635.X  0.329
1993 Nicola NA, Wycherley K, Boyd AW, Layton JE, Cary D, Metcalf D. Neutralizing and nonneutralizing monoclonal antibodies to the human granulocyte-macrophage colony-stimulating factor receptor alpha-chain Blood. 82: 1724-1731. DOI: 10.1182/Blood.V82.6.1724.1724  0.3
1993 Metcalf D. Hematopoietic regulators: redundancy or subtlety? Blood. 82: 3515-3523. DOI: 10.1182/Blood.V82.12.3515.3515  0.399
1992 Metcalf D. Mechanisms responsible for size differences between hemopoietic colonies: an analysis using a CSF-dependent hemopoietic cell line. Stem Cells. 10: 116-125. PMID 1545151 DOI: 10.1002/Stem.5530100209  0.438
1992 Layton MJ, Cross BA, Metcalf D, Ward LD, Simpson RJ, Nicola NA. A major binding protein for leukemia inhibitory factor in normal mouse serum: identification as a soluble form of the cellular receptor. Proceedings of the National Academy of Sciences of the United States of America. 89: 8616-8620. PMID 1528870 DOI: 10.1073/Pnas.89.18.8616  0.323
1992 Metcalf D. The hemopoietic regulators – an embarrassment of riches Bioessays. 14: 799-805. PMID 1365895 DOI: 10.1002/Bies.950141202  0.39
1991 Metcalf D. Transgenic mice as models of hemopoiesis. Cancer. 67: 2695-2699. PMID 2015570 DOI: 10.1002/1097-0142(19910515)67:10+<2695::Aid-Cncr2820671704>3.0.Co;2-M  0.377
1991 Metcalf D. Control of granulocytes and macrophages: molecular, cellular, and clinical aspects. Science. 254: 529-533. PMID 1948028 DOI: 10.1126/Science.1948028  0.393
1991 Hilton DJ, Nicola NA, Waring PM, Metcalf D. Clearance and fate of leukemia-inhibitory factor (LIF) after injection into mice. Journal of Cellular Physiology. 148: 430-439. PMID 1918172 DOI: 10.1002/Jcp.1041480315  0.432
1991 Hilton DJ, Nicola NA, Metcalf D. Distribution and comparison of receptors for leukemia inhibitory factor on murine hemopoietic and hepatic cells. Journal of Cellular Physiology. 146: 207-215. PMID 1900303 DOI: 10.1002/Jcp.1041460204  0.439
1991 Metcalf D. The Florey Lecture, 1991: The Colony-Stimulating Factors: Discovery to Clinical Use Philosophical Transactions of the Royal Society B. 333: 147-173. PMID 1719572 DOI: 10.1098/Rstb.1991.0065  0.357
1991 Metcalf D. The leukemia inhibitory factor (LIF) Stem Cells. 9: 95-108. PMID 1645391 DOI: 10.1002/Stem.5530090201  0.452
1990 Kelso A, Metcalf D. T lymphocyte-derived colony-stimulating factors. Advances in Immunology. 48: 69-105. PMID 2190451 DOI: 10.1016/S0065-2776(08)60752-X  0.455
1990 Villeval J, Dührsen U, Morstyn G, Metcalf D. Effect of recombinant human granulocyte-macrophage colony stimulating factor on progenitor cells in patients with advanced malignancies. British Journal of Haematology. 74: 36-44. PMID 2178672 DOI: 10.1111/J.1365-2141.1990.Tb02535.X  0.411
1990 Metcalf D, Nicola NA, Gearing DP, Gough NM. Low-affinity placenta-derived receptors for human granulocyte-macrophage colony-stimulating factor can deliver a proliferative signal to murine hemopoietic cells. Proceedings of the National Academy of Sciences of the United States of America. 87: 4670-4674. PMID 2162053 DOI: 10.1073/Pnas.87.12.4670  0.397
1990 Metcalf D. The induction and inhibition of differentiation in normal and leukaemic cells Philosophical Transactions of the Royal Society B. 327: 99-109. PMID 1690902 DOI: 10.1098/Rstb.1990.0046  0.467
1990 Metcalf D. The Consequences Of Excess Levels Of Haemopoietic Growth Factors British Journal of Haematology. 75: 1-3. DOI: 10.1111/J.1365-2141.1990.00001.X  0.397
1990 Metcalf D. Colony-stimulating factors Cell. 61: 756-757. DOI: 10.1016/0092-8674(90)90184-G  0.308
1989 Dührsen U, Metcalf D. Factors influencing the time and site of leukemic transformation of factor-dependent cells after injection into irradiated recipient mice. International Journal of Cancer. 44: 1074-1081. PMID 2606574 DOI: 10.1002/Ijc.2910440623  0.431
1989 Chang JM, Metcalf D, Gonda TJ, Johnson GR. Long-term exposure to retrovirally expressed granulocyte-colony-stimulating factor induces a nonneoplastic granulocytic and progenitor cell hyperplasia without tissue damage in mice. Journal of Clinical Investigation. 84: 1488-1496. PMID 2478588 DOI: 10.1172/Jci114324  0.472
1989 Metcalf D. The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells Nature. 339: 27-30. PMID 2469962 DOI: 10.1038/339027A0  0.416
1989 Gearing DP, Nicola NA, Metcalf D, Foote S, Willson TA, Gough NM, Williams RL. Production of leukemia inhibitory factor in Escherichia coli by a novel procedure and its use in maintaining embryonic stem cells in culture Bio/Technology. 7: 1157-1161. DOI: 10.1038/Nbt1189-1157  0.353
1988 Metcalf D. Haemopoietic growth factors. The Medical Journal of Australia. 148: 516-519. PMID 3285154 DOI: 10.5694/J.1326-5377.1988.Tb99462.X  0.308
1988 Simpson RJ, Hilton DJ, Nice EC, Rubira MR, Metcalf D, Gearing DP, Gough NM, Nicola NA. Structural characterization of a murine myeloid leukaemia inhibitory factor. Febs Journal. 175: 541-547. PMID 3261689 DOI: 10.1111/J.1432-1033.1988.Tb14226.X  0.32
1988 Williams RL, Hilton DJ, Pease S, Willson TA, Stewart CL, Gearing DP, Wagner EF, Metcalf D, Nicola NA, Gough NM. Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells. Nature. 336: 684-7. PMID 3143916 DOI: 10.1038/336684A0  0.453
1988 Gough NM, Gearing DP, King JA, Willson TA, Hilton DJ, Nicola NA, Metcalf D. Molecular cloning and expression of the human homologue of the murine gene encoding myeloid leukemia-inhibitory factor Proceedings of the National Academy of Sciences of the United States of America. 85: 2623-2627. PMID 3128791 DOI: 10.1073/Pnas.85.8.2623  0.352
1988 Nicola NA, Peterson L, Hilton DJ, Metcalf D. Cellular processing of murine colony-stimulating factor (Multi-CSF, GM-CSF, G-CSF) receptors by normal hemopoietic cells and cell lines. Growth Factors Journal. 1: 41-49. PMID 2483336 DOI: 10.3109/08977198809000245  0.385
1988 Duhrsen U, Villeval J, Boyd J, Kannourakis G, Morstyn G, Metcalf D. Effects of recombinant human granulocyte colony-stimulating factor on hematopoietic progenitor cells in cancer patients. Blood. 72: 2074-2081. DOI: 10.1182/Blood.V72.6.2074.Bloodjournal7262074  0.437
1988 Begley C, Nicola N, Metcalf D. Proliferation of normal human promyelocytes and myelocytes after a single pulse stimulation by purified GM-CSF or G-CSF. Blood. 71: 640-645. DOI: 10.1182/Blood.V71.3.640.Bloodjournal713640  0.385
1987 Gough NM, Grail D, Gearing DP, Metcalf D. Mutagenesis of murine granulocyte/macrophage-colony-stimulating factor reveals critical residues near the N terminus. Febs Journal. 169: 353-358. PMID 3500855 DOI: 10.1111/J.1432-1033.1987.Tb13619.X  0.365
1987 Lang RA, Metcalf D, Cuthbertson RA, Lyons I, Stanley E, Kelso A, Kannourakis G, Williamson DJ, Klintworth GK, Gonda TJ. Transgenic mice expressing a hemopoietic growth factor gene (GM-CSF) develop accumulations of macrophages, blindness, and a fatal syndrome of tissue damage. Cell. 51: 675-86. PMID 3499986 DOI: 10.1016/0092-8674(87)90136-X  0.373
1987 Begley CG, Metcalf D, Nicola NA. Purified colony stimulating factors (G‐CSF and GM‐CSF) induce differentiation in human HL60 leukemic cells with suppression of clonogenicity International Journal of Cancer. 39: 99-105. PMID 3491793 DOI: 10.1002/Ijc.2910390118  0.462
1987 Metcalf D. Hemopoietic growth factors and oncogenes in myeloid leukemia development. Haematology and Blood Transfusion. 31: 16-25. PMID 3327769 DOI: 10.1007/978-3-642-72624-8_4  0.308
1987 Metcalf D. The role of the colony-stimulating factors in resistance to acute infections. Immunology and Cell Biology. 65: 35-43. PMID 3301635 DOI: 10.1038/Icb.1987.4  0.337
1987 Metcalf D. The Wellcome Foundation Lecture, 1986: The Molecular Control of Normal and Leukaemic Granulocytes and Macrophages Proceedings of the Royal Society B: Biological Sciences. 230: 389-423. PMID 2885849 DOI: 10.1098/Rspb.1987.0026  0.417
1986 Metcalf D. Editorial comment: How reliable are in vitro clonal cultures? some comments based on hemopoietic cultures Stem Cells. 4: 287-294. PMID 3772173 DOI: 10.1002/Stem.5530040501  0.338
1986 Metcalf D, Burgess AW, Johnson GR, Nicola NA, Nice EC, Delamarter J, Thatcher DR, Mermod J-. In vitro actions on hemopoietic cells of recombinant murine GM-CSF purified after production in Escherichia coli: comparison with purified native GM-CSF. Journal of Cellular Physiology. 128: 421-431. PMID 3528176 DOI: 10.1002/Jcp.1041280311  0.413
1986 Nicola NA, Metcalf D. Binding of iodinated multipotential colony-stimulating factor (interleukin-3) to murine bone marrow cells. Journal of Cellular Physiology. 128: 180-188. PMID 3090054 DOI: 10.1002/Jcp.1041280207  0.442
1985 Hozumi M, Metcalf D. Established leukemia cell lines: Their role in the understanding and control of leukemia proliferation Critical Reviews in Oncology Hematology. 3: 235-277. PMID 3899390 DOI: 10.1016/S1040-8428(85)80028-7  0.382
1985 Metcalf D, Nicola NA. Synthesis by mouse peritoneal cells of G-CSF, the differentiation inducer for myeloid leukemia cells: Stimulation by endotoxin, M-CSF and multi-CSF Leukemia Research. 9: 35-50. PMID 3887043 DOI: 10.1016/0145-2126(85)90020-7  0.452
1985 Lang RA, Metcalf D, Gough NM, Dunn AR, Gonda TJ. Expression of a hemopoietic growth factor cDNA in a factor-dependent cell line results in autonomous growth and tumorigenicity Cell. 43: 531-542. PMID 3878229 DOI: 10.1016/0092-8674(85)90182-5  0.409
1985 Metcalf D, Begley CG, Nicola NA. The proliferative effects of human GM-CSFα and β and murine G-CSF in microwell cultures of fractionated human marrow cells Leukemia Research. 9: 521-527. PMID 3874326 DOI: 10.1016/0145-2126(85)90131-6  0.435
1985 Kelso A, Metcalf D. Clonal heterogeneity in colony stimulating factor production by murine T lymphocytes. Journal of Cellular Physiology. 123: 101-110. PMID 3156138 DOI: 10.1002/Jcp.1041230115  0.378
1985 Metcalf D. The granulocyte—Macrophage colony stimulating factors Cell. 43: 5-6. PMID 3000606 DOI: 10.1016/0092-8674(85)90004-2  0.308
1985 Walker F, Nicola NA, Metcalf D, Burgess AW. Hierarchical down-modulation of hemopoietic growth factor receptors Cell. 43: 269-276. PMID 3000602 DOI: 10.1016/0092-8674(85)90032-7  0.384
1985 Metcalf D. The granulocyte-macrophage colony-stimulating factors. Science. 229: 16-22. PMID 2990035 DOI: 10.1126/Science.2990035  0.41
1985 Cook WD, Metcalf D, Nicola NA, Burgess AW, Walker F. Malignant transformation of a growth factor-dependent myeloid cell line by Abelson virus without evidence of an autocrine mechanism. Cell. 41: 677-83. PMID 2988782 DOI: 10.1016/S0092-8674(85)80048-9  0.44
1985 Nicola NA, Begley CG, Metcalf D. Identification of the human analogue of a regulator that induces differentiation in murine leukaemic cells. Nature. 314: 625-628. PMID 2986009 DOI: 10.1038/314625A0  0.444
1984 Gough NM, Gough J, Metcalf D, Kelso A, Grail D, Nicola NA, Burgess AW, Dunn AR. Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte - Macrophage colony stimulating factor Nature. 309: 763-767. PMID 6610831 DOI: 10.1038/309763A0  0.341
1984 Nicola NA, Metcalf D. Binding of the differentiation-inducer, granulocyte-colony-stimulating factor, to responsive but not unresponsive leukemic cell lines Proceedings of the National Academy of Sciences of the United States of America. 81: 3765-3769. PMID 6610179 DOI: 10.1073/Pnas.81.12.3765  0.462
1984 Boyd AW, Metcalf D. Induction of differentiation in HL60 leukaemic cells: A cell cycle dependent all-or-none event Leukemia Research. 8: 27-43. PMID 6538251 DOI: 10.1016/0145-2126(84)90029-8  0.423
1984 Boyd AW, Metcalf D. Activation of human and murine B cells by anti-immunoglobulin antibody: Dependence of the response on the preexisting level of B-cell activation Cellular Immunology. 89: 75-83. PMID 6333289 DOI: 10.1016/0008-8749(84)90199-0  0.332
1984 Gonda TJ, Metcalf D. Expression of myb, myc and fos proto-oncogenes during the differentiation of a murine myeloid leukaemia. Nature. 310: 249-251. PMID 6205276 DOI: 10.1038/310249A0  0.349
1983 Watt SM, Gilmore DJ, Metcalf D, Cobbold SP, Hoang TK, Waldmann H. Segregation of mouse hemopoietic progenitor cells using the monoclonal antibody, YBM/42 Journal of Cellular Physiology. 115: 37-45. PMID 6833407 DOI: 10.1002/Jcp.1041150107  0.399
1983 Nicola NA, Matsumoto M, Metcalf D, Johnson GR. Molecular Properties of a Factor Inducing Differentiation in Murine Myelomonocytic Leukemic Cells Haematology and Blood Transfusion. 28: 345-347. PMID 6602740 DOI: 10.1007/978-3-642-68761-7_65  0.426
1983 Metcalf D. Clonal analysis of the response of HL60 human myeloid leukemia cells to biological regulators Leukemia Research. 7: 117-132. PMID 6602251 DOI: 10.1016/0145-2126(83)90002-4  0.46
1983 Hale G, Bright S, Chumbley G, Hoang T, Metcalf D, Munro AJ, Waldmann H. Removal of T cells from bone marrow for transplantation: a monoclonal antilymphocyte antibody that fixes human complement Blood. 62: 873-882. DOI: 10.1182/Blood.V62.4.873.873  0.376
1983 Hoang T, Gilmore D, Metcalf D, Cobbold S, Watt S, Clark M, Furth M, Waldmann H. Separation of hemopoietic cells from adult mouse marrow by use of monoclonal antibodies Blood. 61: 580-588. DOI: 10.1182/Blood.V61.3.580.580  0.424
1982 Metcalf D, Nicola NA. Autoinduction of differentiation in WEHI-3B leukemia cells. International Journal of Cancer. 30: 773-780. PMID 6984432 DOI: 10.1002/Ijc.2910300616  0.402
1982 Nicola NA, Metcalf D. Analysis of purified fetal liver hemopoietic progenitor cells in liquid culture. Journal of Cellular Physiology. 112: 257-264. PMID 6981651 DOI: 10.1002/Jcp.1041120215  0.456
1982 Metcalf D, Burgess AW. Clonal analysis of progenitor cell commitment to granulocyte or macrophage production Journal of Cellular Physiology. 111: 275-283. PMID 6980223 DOI: 10.1002/Jcp.1041110308  0.419
1982 Dessein AJ, Vadas MA, Nicola NA, Metcalf D, David JR. Enhancement of human blood eosinophil cytotoxicity by semi-purified eosinophil colony-stimulating factor(s). Journal of Experimental Medicine. 156: 90-103. PMID 6979609 DOI: 10.1084/Jem.156.1.90  0.334
1982 Cooper PC, Metcalf D, Burgess AW. Biochemical and functional characterization of mature progeny purified from a myelomonocytic leukemia cell line Leukemia Research. 6: 313-327. PMID 6956783 DOI: 10.1016/0145-2126(82)90093-5  0.423
1981 Morstyn G, Nicola NA, Metcalf D. Separate actions of different colony stimulating factors from human placental conditioned medium on human hemopoietic progenitor cell survival and proliferation. Journal of Cellular Physiology. 109: 133-142. PMID 6976968 DOI: 10.1002/Jcp.1041090115  0.408
1981 Nicola NA, Metcalf D. Biochemical properties of differentiation factors for murine myelomonocytic leukemic cells in organ conditioned media — separation from colony-stimulating factors Journal of Cellular Physiology. 109: 253-264. PMID 6975280 DOI: 10.1002/Jcp.1041090208  0.422
1981 Metcalf D. Induction of differentiation in murine myelomonocytic leukemia cells by the serum of patients with acute myeloid leukemia and other diseases. International Journal of Cancer. 27: 577-584. PMID 6945296 DOI: 10.1002/Ijc.2910270503  0.334
1980 Nicola NA, Burgess AW, Staber FG, Johnson GR, Metcalf D, Battye FL. Differential expression of lectin receptors during hemopoietic differntiation: Enrichment for granulocyte‐macrophage progenitor cells Journal of Cellular Physiology. 103: 217-237. PMID 7440634 DOI: 10.1002/Jcp.1041030207  0.428
1980 Watt SM, Burgess AW, Metcalf D, Battye FL. Isolation of Mouse Bone Marrow Neutrophils by Light Scatter and Autofluorescence Journal of Histochemistry and Cytochemistry. 28: 934-946. PMID 7410816 DOI: 10.1177/28.9.7410816  0.309
1980 Melcher Hv, Metcalf D. Differential seeding of injected hemopoietic precursor cells in the bone marrow and spleen of irradiated mice. Leukemia Research. 4: 393-397. PMID 7230866 DOI: 10.1016/0145-2126(80)90021-1  0.377
1980 Goldschneider I, Metcalf D, Mandel T, Bollum FJ. Analysis of rat hemopoietic cells on the fluorescence-activated cell sorter. II. Isolation of terminal deoxynucleotidyl transferase-positive cells. The Journal of Experimental Medicine. 152: 438-46. PMID 6995555 DOI: 10.1084/Jem.152.2.438  0.397
1980 Goldschneider I, Metcalf D, Battye F, Mandel T. Analysis of rat hemopoietic cells on the fluorescence-activated cell sorter. I. Isolation of pluripotent hemopoietic stem cells and granulocyte-macrophage progenitor cells. The Journal of Experimental Medicine. 152: 419-37. PMID 6995554 DOI: 10.1084/Jem.152.2.419  0.426
1980 Burgess AW, Metcalf D. Characterization of a serum factor stimulating the differentiation of myelomonocytic leukemic cells International Journal of Cancer. 26: 647-654. PMID 6972358 DOI: 10.1002/Ijc.2910260517  0.446
1980 Metcalf D. Clonal analysis of proliferation and differentiation of paired daughter cells: action of granulocyte-macrophage colony-stimulating factor on granulocyte-macrophage precursors. Proceedings of the National Academy of Sciences of the United States of America. 77: 5327-5330. PMID 6968910 DOI: 10.1073/Pnas.77.9.5327  0.437
1980 Burgess AW, Metcalf D, Russell SHM, Nicola NA. Granulocyte/macrophage-, megakaryocyte-, eosinophil- and erythroid-colony-stimulating factors produced by mouse spleen cells. Biochemical Journal. 185: 301-314. PMID 6967311 DOI: 10.1042/Bj1850301  0.377
1980 Metcalf D. Clonal extinction of myelomonocytic leukemic cells by serum from mice injected with endotoxin. International Journal of Cancer. 25: 225-233. PMID 6967053 DOI: 10.1002/Ijc.2910250210  0.419
1980 McCarthy JH, Burgess T, Metcalf D. In vitro Haemopoietic progenitor cell responses in mice with the transplanted lymphoid tumour ABE-8 Pathology. 12: 319. DOI: 10.1016/S0031-3025(16)38574-9  0.472
1980 McCarthy J, Nichola N, Szelarg G, Garson OM, Metcalf D. Eosinophil colonies in agar Pathology. 12: 310. DOI: 10.1016/S0031-3025(16)38550-6  0.344
1979 Metcalf D. Clonal analysis of the action of GM‐CSF on the proliferation and differentiation of myelomonocytic leukemic cells International Journal of Cancer. 24: 616-623. PMID 316807 DOI: 10.1002/Ijc.2910240515  0.449
1979 Howard M, Burgess A, McPhee D, Metcalf D. T-cell hybridoma secreting hemopoietic regulatory molecules: Granulocyte-macrophage and eosinophil colony-stimulating factors Cell. 18: 993-999. PMID 316364 DOI: 10.1016/0092-8674(79)90211-3  0.431
1979 Watt SM, Burgess AW, Metcalf D. Isolation and surface labeling of murine polymorphonuclear neutrophils Journal of Cellular Physiology. 100: 1-22. PMID 313932 DOI: 10.1002/Jcp.1041000102  0.332
1979 Johnson GR, Nicholas WL, Metcalf D, McKenzie IFC, Mitchell GF. Peritoneal cell population of mice infected with Mesocestoides corti as a source of eosinophils. International Archives of Allergy and Immunology. 59: 315-322. PMID 312773 DOI: 10.1159/000232275  0.332
1979 Metcalf D. Potentiation of erythroid colony formation in fetal liver cultures containing serum from patients with hemochromatosis or acute myeloid leukemia Leukemia Research. 3: 341-349. PMID 293458 DOI: 10.1016/0145-2126(79)90060-2  0.37
1978 Rabellino E, Ross G, Trang H, Williams N, Metcalf D. Membrane receptors of mouse leukocytes. II. Sequential expression of membrane receptors and phagocytic capacity during leukocyte differentiation. Journal of Experimental Medicine. 147: 434-445. PMID 624905 DOI: 10.1084/Jem.147.2.434  0.38
1978 Burgess AW, Metcalf D, Watt SM. Regulation of hemopoietic cell differentiation and proliferation Journal of Supramolecular and Cellular Biochemistry. 8: 489-500. PMID 309973 DOI: 10.1002/Jss.400080411  0.471
1977 Burgess AW, Metcalf D. The effect of colony stimulating factor on the synthesis of ribonucleic acid by mouse bone marrow cells in vitro Journal of Cellular Physiology. 90: 471-483. PMID 300739 DOI: 10.1002/Jcp.1040900311  0.414
1976 Metcalf D. B-Lymphocyte Colony Formation In Vitro Leukocyte Membrane Determinants Regulating Immune Reactivity. 689-694. DOI: 10.1016/B978-0-12-233750-5.50133-0  0.399
1975 Metcalf D, MacDonald HR, Odartchenko N, Sordat B. Growth of mouse megakaryocyte colonies in vitro Proceedings of the National Academy of Sciences of the United States of America. 72: 1744-1748. PMID 1098043 DOI: 10.1073/Pnas.72.5.1744  0.437
1975 Metcalf D, Warner NL, Nossal GJ, Miller JF, Shortman K, Rabellino E. Growth of B lymphocyte colonies in vitro from mouse lymphoid organs. Nature. 255: 630-2. PMID 1079572 DOI: 10.1038/255630A0  0.406
1974 Sheridan JW, Metcalf D. Purification of mouse lung-conditioned medium colony stimulating factor (CSF). Experimental Biology and Medicine. 146: 218-221. PMID 4597167 DOI: 10.3181/00379727-146-38073  0.31
1974 Moore MA, Metcalf D. Cytogenetic analysis of human acute and chronic myeloid leukemic cells cloned in agar culture. International Journal of Cancer. 11: 143-52. PMID 4524548 DOI: 10.1002/Ijc.2910110117  0.361
1974 Moore MAS, Spitzer G, Williams N, Metcalf D, Buckley J. Agar culture studies in 127 cases of untreated acute leukemia: the prognostic value of reclassification of leukemia according to in vitro growth characteristics. Blood. 44: 1-18. DOI: 10.1182/Blood.V44.1.1.1  0.306
1974 Metcalf D. Introduction To Hematopoietic Stem Cells Blood. 251-288. DOI: 10.1016/B978-0-12-595705-2.50015-X  0.345
1973 Sheridan JW, Metcalf D. The Bone Marrow Colony Stimulating Factor (CSF): Relation of Serum CSF to Urine CSF Experimental Biology and Medicine. 144: 785-788. PMID 4587883 DOI: 10.3181/00379727-144-37682  0.34
1972 Metcalf D. Effect of thymidine suiciding on colony formation in vitro by mouse hematopoietic cells. Experimental Biology and Medicine. 139: 511-514. PMID 5059041 DOI: 10.3181/00379727-139-36175  0.434
1972 Metcalf D. Formation in agar of fibroblast-like colonies by cells from the mouse pleural cavity and other sources. Journal of Cellular Physiology. 80: 409-419. PMID 4567381 DOI: 10.1002/Jcp.1040800311  0.475
1972 Metcalf D. New type of colony-forming cell located in the pleural cavity. Nature. 238: 253-254. PMID 4507301 DOI: 10.1038/Newbio238253A0  0.369
1972 Metcalf D. The colony stimulating factor (CSF). Immunology and Cell Biology. 50: 547-557. PMID 4119644 DOI: 10.1038/Icb.1972.48  0.334
1972 Chan SH, Metcalf D. Local Production of Colony-stimulating Factor Within the Bone Marrow: Role of Nonhematopoietic Cells Blood. 40: 646-653. DOI: 10.1182/Blood.V40.5.646.646  0.441
1971 Metcalf D, Stanley ER. Serum half life in mice of colony stimulating factor prepared from human urine. British Journal of Haematology. 20: 549-556. PMID 5579457 DOI: 10.1111/J.1365-2141.1971.Tb07070.X  0.387
1971 Metcalf D. Transformation of granulocytes to macrophages in bone marrow colonies in vitro. Journal of Cellular Physiology. 77: 277-280. PMID 5572429 DOI: 10.1002/Jcp.1040770216  0.379
1971 Chan SH, Metcalf D, Stanley ER. Stimulation and inhibition by normal human serum of colony formation in vitro by bone marrow cells. British Journal of Haematology. 20: 329-341. PMID 5552361 DOI: 10.1111/J.1365-2141.1971.Tb07043.X  0.4
1971 Foster RS, Metcalf D, Cortner J. Bone marrow colony-stimulating activity in sera of children with acute leukemia. A sequential analysis Cancer. 27: 881-886. PMID 5280375 DOI: 10.1002/1097-0142(197104)27:4<881::Aid-Cncr2820270418>3.0.Co;2-C  0.351
1971 Metcalf D, Stanley ER. Haematological effects in mice of partially purified colony stimulating factor (CSF) prepared from human urine. British Journal of Haematology. 21: 481-492. PMID 5122671 DOI: 10.1111/J.1365-2141.1971.Tb02709.X  0.444
1971 Metcalf D. Humoral regulators in the development and progression of leukemia. Advances in Cancer Research. 14: 181-230. PMID 4399428 DOI: 10.1016/S0065-230X(08)60521-7  0.421
1971 Metcalf D, Chan SH, Gunz FW, Vincent P, Ravich RBM. Colony-stimulating Factor and Inhibitor Levels in Acute Granulocytic Leukemia Blood. 38: 143-152. DOI: 10.1182/Blood.V38.2.143.143  0.307
1970 Moore MAS, Metcalf D. Ontogeny of the haemopoietic system: yolk sac origin of in vivo and in vitro colony forming cells in the developing mouse embryo. British Journal of Haematology. 18: 279-296. PMID 5491581 DOI: 10.1111/J.1365-2141.1970.Tb01443.X  0.437
1970 Metcalf D. Studies on colony formation in vitro by mouse bone marrow cells. II. Action of colony stimulating factor Journal of Cellular Physiology. 76: 89-99. PMID 5471044 DOI: 10.1002/Jcp.1040760113  0.396
1970 Chan SH, Metcalf D. Inhibition of bone marrow colony formation by normal and leukaemic human serum Nature. 227: 845-846. PMID 5270449 DOI: 10.1038/227845A0  0.396
1970 Metcalf D, Moore MAS. Factors Modifying Stem Cell Proliferation of Myelomonocytic Leukemic Cells In Vitro and In Vivo Journal of the National Cancer Institute. 44: 801-808. DOI: 10.1093/Jnci/44.4.801  0.418
1969 Metcalf D. The effect of bleeding on the number of in vitro colony-forming cells in the bone marrow. British Journal of Haematology. 16: 397-408. PMID 5795501 DOI: 10.1111/J.1365-2141.1969.Tb00417.X  0.443
1969 Metcalf D. Studies on colony formation in vitro by mouse bone marrow cells. I. Continuous cluster formation and relation of clusters to colonies. Journal of Cellular Physiology. 74: 323-332. PMID 5390860 DOI: 10.1002/Jcp.1040740313  0.317
1969 Metcalf D. Cortisone Action on Serum Colony-Stimulating Factor and Bone Marrow in Vitro Colony-Forming Cells Experimental Biology and Medicine. 132: 391-394. PMID 5344865 DOI: 10.3181/00379727-132-34222  0.404
1969 Metcalf D, Moore MAS, Warner NL. Colony Formation In Vitro by Myelomonocytic Leukemic Cells Journal of the National Cancer Institute. 43: 983-1001. DOI: 10.1093/Jnci/43.4.983  0.416
1968 Metcalf D. Potentiation of bone marrow colony growth in vitro by the addition of lymphoid or bone marrow cells. Journal of Cellular Physiology. 72: 9-19. PMID 5692692 DOI: 10.1002/Jcp.1040720104  0.395
1968 Foster R, Metcalf D, Kirchmyer R. Induction Of Bone Marrow Colony-Stimulating Activity By A Filterable Agent In Leukemic And Normal Mouse Serum Journal of Experimental Medicine. 127: 853-866. PMID 5655100 DOI: 10.1084/Jem.127.5.853  0.362
1968 Foster R, Metcalf D, Robinson WA, Bradley TR. Bone marrow colony stimulating activity in human sera. Results of two independent surveys in Buffalo and Melbourne. British Journal of Haematology. 15: 147-59. PMID 4877511 DOI: 10.1111/J.1365-2141.1968.Tb01524.X  0.39
1967 Metcalf D, Moulds R. Immune responses in preleukaemic and leukaemic akr mice. International Journal of Cancer. 2: 53-58. PMID 6036065 DOI: 10.1002/Ijc.2910020109  0.385
1967 Metcalf D, Brumby M. Coulter counter analysis of lymphoma differentiation patterns in AKR mice with lymphoid leukaemia International Journal of Cancer. 2: 37-42. PMID 6036063 DOI: 10.1002/Ijc.2910020107  0.333
1967 Bradley TR, Robinson W, Metcalf D. Colony production in vitro by normal polycythaemic and anaemic bone marrow. Nature. 214: 511. PMID 6032887 DOI: 10.1038/214511A0  0.454
1967 Bradley TR, Metcalf D, Robinson W. Stimulation by leukaemic sera of colony formation in solid agar cultures by proliferation of mouse bone marrow cells. Nature. 213: 926-7. PMID 6030063 DOI: 10.1038/213926A0  0.447
1967 Robinson WA, Bradley TR, Metcalf D. Effect of whole body irradiation on colony production by bone marrow cells in vitro. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 125: 388-91. PMID 6028553 DOI: 10.3181/00379727-125-32099  0.365
1967 Brumby M, Metcalf D. Migration of cells to the thymus demonstrated by parabiosis. Experimental Biology and Medicine. 124: 99-103. PMID 6017799 DOI: 10.3181/00379727-124-31675  0.352
1967 Metcalf D, Foster R, Pollard M. Colony stimulating activity of serum from germfree normal and leukemic mice Journal of Cellular Physiology. 70: 131-132. PMID 5584609 DOI: 10.1002/Jcp.1040700118  0.407
1967 Brumby M, Metcalf D. Migration of cells to the thymus demonstrated by parabiosis Transplantation. 5: 1543. DOI: 10.1097/00007890-196711000-00030  0.386
1967 Metcalf D, Ishidate M, Brumby M. Proliferation and behavior of phagocytic cells in mouse lymphoma tissue. Journal of the National Cancer Institute. 38: 527-539. DOI: 10.1093/Jnci/38.4.527  0.313
1966 Metcalf D, Brumby M. The role of the thymus in the ontogeny of the immune system Journal of Cellular Physiology. 67: 149-167. PMID 5964883 DOI: 10.1002/Jcp.1040670413  0.399
1964 Metcalf D, Wakonig-Vaartaja R. Stem Cell Replacement In Normal Thymus Grafts. Experimental Biology and Medicine. 115: 731-735. PMID 14155813 DOI: 10.3181/00379727-115-29022  0.392
1963 Wiadrowski M, Metcalf D. Erythrocyte osmotic fragility in AKR mice with lymphoid leukaemia. Nature. 198: 1103-1104. PMID 14000448 DOI: 10.1038/1981103B0  0.313
1963 Wakonig-Vaartaja R, Metcalf D. The origin of mitotic cells in normal thymus grafts. The Lancet. 281: 1302-1304. PMID 13998394 DOI: 10.1016/S0140-6736(63)91993-7  0.327
1961 Metcalf D, Ishidate M. Periodic acid-Schiff positive giant cells in the mouse thymus cortex. Nature. 191: 305-305. PMID 13769850 DOI: 10.1038/191305A0  0.355
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