| Year |
Citation |
Score |
| 2023 |
Bhowmick R, Hickson ID, Liu Y. Completing genome replication outside of S phase. Molecular Cell. PMID 37716351 DOI: 10.1016/j.molcel.2023.08.023 |
0.362 |
|
| 2023 |
Hertz EPT, Vega IA, Kruse T, Wang Y, Hendriks IA, Bizard AH, Eugui-Anta A, Hay RT, Nielsen ML, Nilsson J, Hickson ID, Mailand N. The SUMO-NIP45 pathway processes toxic DNA catenanes to prevent mitotic failure. Nature Structural & Molecular Biology. PMID 37474739 DOI: 10.1038/s41594-023-01045-0 |
0.363 |
|
| 2022 |
Bhowmick R, Lerdrup M, Gadi SA, Rossetti GG, Singh MI, Liu Y, Halazonetis TD, Hickson ID. RAD51 protects human cells from transcription-replication conflicts. Molecular Cell. PMID 36002000 DOI: 10.1016/j.molcel.2022.07.010 |
0.343 |
|
| 2022 |
Bakx JAM, Biebricher AS, King GA, Christodoulis P, Sarlós K, Bizard AH, Hickson ID, Wuite GJL, Peterman EJG. Duplex DNA and BLM regulate gate opening by the human TopoIIIα-RMI1-RMI2 complex. Nature Communications. 13: 584. PMID 35102151 DOI: 10.1038/s41467-022-28082-5 |
0.307 |
|
| 2020 |
Brannvoll A, Xue X, Kwon Y, Kompocholi S, Simonsen AKW, Viswalingam KS, Gonzalez L, Hickson ID, Oestergaard VH, Mankouri HW, Sung P, Lisby M. The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells. Cell Reports. 32: 107849. PMID 32640219 DOI: 10.1016/J.Celrep.2020.107849 |
0.367 |
|
| 2020 |
Garribba L, Bjerregaard VA, Gonçalves Dinis MM, Özer Ö, Wu W, Sakellariou D, Pena-Diaz J, Hickson ID, Liu Y. Folate stress induces SLX1- and RAD51-dependent mitotic DNA synthesis at the fragile X locus in human cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 32601218 DOI: 10.1073/pnas.1921219117 |
0.387 |
|
| 2020 |
Macheret M, Bhowmick R, Sobkowiak K, Padayachy L, Mailler J, Hickson ID, Halazonetis TD. High-resolution mapping of mitotic DNA synthesis regions and common fragile sites in the human genome through direct sequencing. Cell Research. PMID 32561860 DOI: 10.1038/S41422-020-0358-X |
0.376 |
|
| 2020 |
Carbone M, Arron ST, Beutler B, Bononi A, Cavenee W, Cleaver JE, Croce CM, D'Andrea A, Foulkes WD, Gaudino G, Groden JL, Henske EP, Hickson ID, Hwang PM, Kolodner RD, et al. Tumour predisposition and cancer syndromes as models to study gene-environment interactions. Nature Reviews. Cancer. PMID 32472073 DOI: 10.1038/S41568-020-0265-Y |
0.319 |
|
| 2020 |
Wu W, Bhowmick R, Vogel I, Özer Ö, Ghisays F, Thakur RS, Sanchez de Leon E, Richter PH, Ren L, Petrini JH, Hickson ID, Liu Y. RTEL1 suppresses G-quadruplex-associated R-loops at difficult-to-replicate loci in the human genome. Nature Structural & Molecular Biology. 27: 424-437. PMID 32398827 DOI: 10.1038/S41594-020-0408-6 |
0.598 |
|
| 2020 |
Xing M, Zhang F, Liao H, Chen S, Che L, Wang X, Bao Z, Ji F, Chen G, Zhang H, Li W, Chen Z, Liu Y, Hickson ID, Shen H, et al. Replication Stress Induces ATR/CHK1-Dependent Nonrandom Segregation of Damaged Chromosomes. Molecular Cell. PMID 32353258 DOI: 10.1016/j.molcel.2020.04.005 |
0.398 |
|
| 2020 |
Venegas AB, Natsume T, Kanemaki M, Hickson ID. Inducible Degradation of the Human SMC5/6 Complex Reveals an Essential Role Only during Interphase. Cell Reports. 31: 107533. PMID 32320646 DOI: 10.1016/j.celrep.2020.107533 |
0.322 |
|
| 2020 |
Bizard AH, Hickson ID. The many lives of type IA topoisomerases. The Journal of Biological Chemistry. 295: 7138-7153. PMID 32277049 DOI: 10.1074/jbc.REV120.008286 |
0.32 |
|
| 2020 |
Wu W, Hickson ID, Liu Y. The prevention and resolution of DNA replication–transcription conflicts in eukaryotic cells Genome Instability & Disease. 1: 114-128. DOI: 10.1007/s42764-020-00012-z |
0.375 |
|
| 2019 |
Achuthankutty D, Thakur RS, Haahr P, Hoffmann S, Drainas AP, Bizard AH, Weischenfeldt J, Hickson ID, Mailand N. Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability. The Journal of Cell Biology. PMID 31615875 DOI: 10.1083/Jcb.201905064 |
0.627 |
|
| 2019 |
Sonneville R, Bhowmick R, Hoffmann S, Mailand N, Hickson ID, Labib K. TRAIP drives replisome disassembly and mitotic DNA repair synthesis at sites of incomplete DNA replication. Elife. 8. PMID 31545170 DOI: 10.7554/Elife.48686 |
0.38 |
|
| 2019 |
Taylor AMR, Rothblum-Oviatt C, Ellis NA, Hickson ID, Meyer S, Crawford TO, Smogorzewska A, Pietrucha B, Weemaes C, Stewart GS. Chromosome instability syndromes. Nature Reviews. Disease Primers. 5: 64. PMID 31537806 DOI: 10.1038/s41572-019-0113-0 |
0.353 |
|
| 2019 |
Bhowmick R, Thakur RS, Venegas AB, Liu Y, Nilsson J, Barisic M, Hickson ID. The RIF1-PP1 Axis Controls Abscission Timing in Human Cells. Current Biology : Cb. PMID 30905608 DOI: 10.1016/J.Cub.2019.02.037 |
0.603 |
|
| 2019 |
Jørgensen SW, Liberti SE, Larsen NB, Lisby M, Mankouri HW, Hickson ID. Esc2 promotes telomere stability in response to DNA replication stress. Nucleic Acids Research. PMID 30838410 DOI: 10.1093/nar/gkz158 |
0.393 |
|
| 2019 |
Sonneville R, Bhowmick R, Hoffmann S, Mailand N, Hickson ID, Labib K. Author response: TRAIP drives replisome disassembly and mitotic DNA repair synthesis at sites of incomplete DNA replication Elife. DOI: 10.7554/Elife.48686.017 |
0.3 |
|
| 2018 |
Bjerregaard VA, Garribba L, McMurray CT, Hickson ID, Liu Y. Folate deficiency drives mitotic missegregation of the human locus. Proceedings of the National Academy of Sciences of the United States of America. 115: 13003-13008. PMID 30509972 DOI: 10.1073/pnas.1808377115 |
0.328 |
|
| 2018 |
Martin CA, Sarlós K, Logan CV, Thakur RS, Parry DA, Bizard AH, Leitch A, Cleal L, Ali NS, Al-Owain MA, Allen W, Altmüller J, Aza-Carmona M, Barakat BAY, Barraza-García J, ... ... Hickson ID, et al. Mutations in TOP3A Cause a Bloom Syndrome-like Disorder. American Journal of Human Genetics. 103: 456. PMID 30193137 DOI: 10.1016/J.Ajhg.2018.08.012 |
0.527 |
|
| 2018 |
Sarlós K, Biebricher AS, Bizard AH, Bakx JAM, Ferreté-Bonastre AG, Modesti M, Paramasivam M, Yao Q, Peterman EJG, Wuite GJL, Hickson ID. Reconstitution of anaphase DNA bridge recognition and disjunction. Nature Structural & Molecular Biology. PMID 30177760 DOI: 10.1038/S41594-018-0123-8 |
0.355 |
|
| 2018 |
Martin CA, Sarlós K, Logan CV, Thakur RS, Parry DA, Bizard AH, Leitch A, Cleal L, Ali NS, Al-Owain MA, Allen W, Altmüller J, Aza-Carmona M, Barakat BAY, Barraza-García J, ... ... Hickson ID, et al. Mutations in TOP3A Cause a Bloom Syndrome-like Disorder. American Journal of Human Genetics. PMID 30057030 DOI: 10.1016/J.Ajhg.2018.07.001 |
0.596 |
|
| 2018 |
Özer Ö, Hickson ID. Pathways for maintenance of telomeres and common fragile sites during DNA replication stress. Open Biology. 8. PMID 29695617 DOI: 10.1098/rsob.180018 |
0.376 |
|
| 2018 |
Zhang BN, Bueno Venegas A, Hickson ID, Chu WK. DNA replication stress and its impact on chromosome segregation and tumorigenesis. Seminars in Cancer Biology. PMID 29692334 DOI: 10.1016/j.semcancer.2018.04.005 |
0.358 |
|
| 2018 |
Özer Ö, Bhowmick R, Liu Y, Hickson ID. Human cancer cells utilize mitotic DNA synthesis to resist replication stress at telomeres regardless of their telomere maintenance mechanism. Oncotarget. 9: 15836-15846. PMID 29662610 DOI: 10.18632/oncotarget.24745 |
0.374 |
|
| 2018 |
Garribba L, Wu W, Özer Ö, Bhowmick R, Hickson ID, Liu Y. Inducing and Detecting Mitotic DNA Synthesis at Difficult-to-Replicate Loci. Methods in Enzymology. 601: 45-58. PMID 29523241 DOI: 10.1016/bs.mie.2017.11.025 |
0.4 |
|
| 2018 |
Larsen NB, Hickson ID, Mankouri HW. A Molecular Toolbox to Engineer Site-Specific DNA Replication Perturbation. Methods in Molecular Biology (Clifton, N.J.). 1672: 295-309. PMID 29043631 DOI: 10.1007/978-1-4939-7306-4_20 |
0.317 |
|
| 2017 |
Sarlós K, Biebricher A, Petermann EJG, Wuite GJL, Hickson ID. Knotty Problems during Mitosis: Mechanistic Insight into the Processing of Ultrafine DNA Bridges in Anaphase. Cold Spring Harbor Symposia On Quantitative Biology. 82: 187-195. PMID 29167280 DOI: 10.1101/Sqb.2017.82.033647 |
0.371 |
|
| 2017 |
Larsen NB, Liberti SE, Vogel I, Jørgensen SW, Hickson ID, Mankouri HW. Stalled replication forks generate a distinct mutational signature in yeast. Proceedings of the National Academy of Sciences of the United States of America. PMID 28827358 DOI: 10.1073/pnas.1706640114 |
0.425 |
|
| 2017 |
Bhowmick R, Hickson ID. The "enemies within": regions of the genome that are inherently difficult to replicate. F1000research. 6: 666. PMID 28620461 DOI: 10.12688/f1000research.11024.1 |
0.365 |
|
| 2017 |
Di Marco S, Hasanova Z, Kanagaraj R, Chappidi N, Altmannova V, Menon S, Sedlackova H, Langhoff J, Surendranath K, Hühn D, Bhowmick R, Marini V, Ferrari S, Hickson ID, Krejci L, et al. RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis. Molecular Cell. 66: 658-671.e8. PMID 28575661 DOI: 10.1016/J.Molcel.2017.05.006 |
0.38 |
|
| 2017 |
Natsume T, Nishimura K, Minocherhomji S, Bhowmick R, Hickson ID, Kanemaki MT. Acute inactivation of the replicative helicase in human cells triggers MCM8-9-dependent DNA synthesis. Genes & Development. PMID 28487407 DOI: 10.1101/gad.297663.117 |
0.388 |
|
| 2016 |
Bhowmick R, Minocherhomji S, Hickson ID. RAD52 Facilitates Mitotic DNA Synthesis Following Replication Stress. Molecular Cell. 64: 1117-1126. PMID 27984745 DOI: 10.1016/j.molcel.2016.10.037 |
0.352 |
|
| 2016 |
Nielsen CF, Hickson ID. PICH promotes mitotic chromosome segregation: Identification of a novel role in rDNA disjunction. Cell Cycle (Georgetown, Tex.). 15: 2704-11. PMID 27565185 DOI: 10.1080/15384101.2016.1222336 |
0.364 |
|
| 2016 |
Ahuja AK, Jodkowska K, Teloni F, Bizard AH, Zellweger R, Herrador R, Ortega S, Hickson ID, Altmeyer M, Mendez J, Lopes M. A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells. Nature Communications. 7: 10660. PMID 26876348 DOI: 10.1038/Ncomms10660 |
0.333 |
|
| 2016 |
Ghamrasni SE, Cardoso R, Li L, Guturi KK, Bjerregaard VA, Liu Y, Venkatesan S, Hande MP, Henderson JT, Sanchez O, Hickson ID, Hakem A, Hakem R. Rad54 and Mus81 cooperation promotes DNA damage repair and restrains chromosome missegregation. Oncogene. PMID 26876210 DOI: 10.1038/onc.2016.16 |
0.346 |
|
| 2015 |
Nielsen CF, Huttner D, Bizard AH, Hirano S, Li TN, Palmai-Pallag T, Bjerregaard VA, Liu Y, Nigg EA, Wang LH, Hickson ID. PICH promotes sister chromatid disjunction and co-operates with topoisomerase II in mitosis. Nature Communications. 6: 8962. PMID 26643143 DOI: 10.1038/Ncomms9962 |
0.32 |
|
| 2015 |
Minocherhomji S, Ying S, Bjerregaard VA, Bursomanno S, Aleliunaite A, Wu W, Mankouri HW, Shen H, Liu Y, Hickson ID. Replication stress activates DNA repair synthesis in mitosis. Nature. PMID 26633632 DOI: 10.1038/nature16139 |
0.383 |
|
| 2015 |
Minocherhomji S, Ying S, Bjerregaard VA, Bursomanno S, Aleliunaite A, Wu W, Mankouri HW, Shen H, Liu Y, Hickson ID. Replication stress activates DNA repair synthesis in mitosis. Nature. PMID 26618877 DOI: 10.1038/nature16139 |
0.309 |
|
| 2015 |
Kliszczak M, Sedlackova H, Pitchai GP, Streicher WW, Krejci L, Hickson ID. Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells. Oncotarget. 6: 40464-79. PMID 26588054 DOI: 10.18632/oncotarget.6342 |
0.334 |
|
| 2015 |
Xing M, Wang X, Palmai-Pallag T, Shen H, Helleday T, Hickson ID, Ying S. Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response. Oncotarget. PMID 26415217 DOI: 10.18632/oncotarget.5497 |
0.37 |
|
| 2015 |
Fugger K, Mistrik M, Neelsen KJ, Yao Q, Zellweger R, Kousholt AN, Haahr P, Chu WK, Bartek J, Lopes M, Hickson ID, Sørensen CS. FBH1 Catalyzes Regression of Stalled Replication Forks. Cell Reports. PMID 25772361 DOI: 10.1016/j.celrep.2015.02.028 |
0.377 |
|
| 2015 |
Bursomanno S, McGouran JF, Kessler BM, Hickson ID, Liu Y. Regulation of SUMO2 target proteins by the proteasome in human cells exposed to replication stress. Journal of Proteome Research. 14: 1687-99. PMID 25748227 DOI: 10.1021/pr500997p |
0.332 |
|
| 2015 |
Chu WK, Payne MJ, Beli P, Hanada K, Choudhary C, Hickson ID. FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51. Nature Communications. 6: 5931. PMID 25585578 DOI: 10.1038/Ncomms6931 |
0.342 |
|
| 2015 |
Perez-Oliva AB, Lachaud C, Szyniarowski P, Muñoz I, Macartney T, Hickson I, Rouse J, Alessi DR. USP45 deubiquitylase controls ERCC1-XPF endonuclease-mediated DNA damage responses. The Embo Journal. 34: 326-43. PMID 25538220 DOI: 10.15252/Embj.201489184 |
0.348 |
|
| 2015 |
Bursomanno S, Beli P, Khan AM, Minocherhomji S, Wagner SA, Bekker-Jensen S, Mailand N, Choudhary C, Hickson ID, Liu Y. Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells. Dna Repair. 25: 84-96. PMID 25497329 DOI: 10.1016/J.Dnarep.2014.10.011 |
0.37 |
|
| 2014 |
Larsen NB, Hickson ID, Mankouri HW. Tus-Ter as a tool to study site-specific DNA replication perturbation in eukaryotes Cell Cycle. 13: 2994-2998. PMID 25486560 DOI: 10.4161/15384101.2014.958912 |
0.337 |
|
| 2014 |
Liu Y, Nielsen CF, Yao Q, Hickson ID. The origins and processing of ultra fine anaphase DNA bridges. Current Opinion in Genetics & Development. 26: 1-5. PMID 24795279 DOI: 10.1016/j.gde.2014.03.003 |
0.315 |
|
| 2014 |
Larsen NB, Sass E, Suski C, Mankouri HW, Hickson ID. The Escherichia coli Tus-Ter replication fork barrier causes site-specific DNA replication perturbation in yeast Nature Communications. 5: 3574. PMID 24705096 DOI: 10.1038/ncomms4574 |
0.307 |
|
| 2014 |
Minocherhomji S, Hickson ID. Structure-specific endonucleases: guardians of fragile site stability. Trends in Cell Biology. 24: 321-7. PMID 24361091 DOI: 10.1016/j.tcb.2013.11.007 |
0.347 |
|
| 2013 |
Simandlova J, Zagelbaum J, Payne MJ, Chu WK, Shevelev I, Hanada K, Chatterjee S, Reid DA, Liu Y, Janscak P, Rothenberg E, Hickson ID. FBH1 helicase disrupts RAD51 filaments in vitro and modulates homologous recombination in mammalian cells. The Journal of Biological Chemistry. 288: 34168-80. PMID 24108124 DOI: 10.1074/Jbc.M113.484493 |
0.354 |
|
| 2013 |
Grabarz A, Guirouilh-Barbat J, Barascu A, Pennarun G, Genet D, Rass E, Germann SM, Bertrand P, Hickson ID, Lopez BS. A role for BLM in double-strand break repair pathway choice: prevention of CtIP/Mre11-mediated alternative nonhomologous end-joining. Cell Reports. 5: 21-8. PMID 24095737 DOI: 10.1016/J.Celrep.2013.08.034 |
0.305 |
|
| 2013 |
Rosenthal AS, Dexheimer TS, Gileadi O, Nguyen GH, Chu WK, Hickson ID, Jadhav A, Simeonov A, Maloney DJ. Synthesis and SAR studies of 5-(pyridin-4-yl)-1,3,4-thiadiazol-2-amine derivatives as potent inhibitors of Bloom helicase. Bioorganic & Medicinal Chemistry Letters. 23: 5660-6. PMID 24012121 DOI: 10.1016/J.Bmcl.2013.08.025 |
0.359 |
|
| 2013 |
Biebricher A, Hirano S, Enzlin JH, Wiechens N, Streicher WW, Huttner D, Wang LH, Nigg EA, Owen-Hughes T, Liu Y, Peterman E, Wuite GJ, Hickson ID. PICH: a DNA translocase specially adapted for processing anaphase bridge DNA. Molecular Cell. 51: 691-701. PMID 23973328 DOI: 10.1016/J.Molcel.2013.07.016 |
0.321 |
|
| 2013 |
Fugger K, Chu WK, Haahr P, Kousholt AN, Beck H, Payne MJ, Hanada K, Hickson ID, Sørensen CS. FBH1 co-operates with MUS81 in inducing DNA double-strand breaks and cell death following replication stress. Nature Communications. 4: 1423. PMID 23361013 DOI: 10.1038/ncomms2395 |
0.361 |
|
| 2013 |
Larsen NB, Hickson ID. RecQ Helicases: Conserved Guardians of Genomic Integrity. Advances in Experimental Medicine and Biology. 767: 161-84. PMID 23161011 DOI: 10.1007/978-1-4614-5037-5_8 |
0.34 |
|
| 2013 |
Biebricher A, Hirano S, Enzlin J, Peterman E, Hickson I, Wuite GJL. PICH: A DNA Translocase Essential for Resolving Anaphase Bridged DNA Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.2992 |
0.446 |
|
| 2011 |
Eppink B, Tafel AA, Hanada K, van Drunen E, Hickson ID, Essers J, Kanaar R. The response of mammalian cells to UV-light reveals Rad54-dependent and independent pathways of homologous recombination. Dna Repair. 10: 1095-105. PMID 21885354 DOI: 10.1016/j.dnarep.2011.08.006 |
0.339 |
|
| 2011 |
Ying S, Hickson ID. Fanconi anaemia proteins are associated with sister chromatid bridging in mitosis. International Journal of Hematology. 93: 440-445. PMID 21472397 DOI: 10.1007/s12185-011-0818-7 |
0.371 |
|
| 2011 |
Lukas C, Savic V, Bekker-Jensen S, Doil C, Neumann B, Pedersen RS, Grøfte M, Chan KL, Hickson ID, Bartek J, Lukas J. 53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress. Nature Cell Biology. 13: 243-53. PMID 21317883 DOI: 10.1038/Ncb2201 |
0.348 |
|
| 2011 |
Suhasini AN, Rawtani NA, Wu Y, Sommers JA, Sharma S, Mosedale G, North PS, Cantor SB, Hickson ID, Brosh RM. Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome. The Embo Journal. 30: 692-705. PMID 21240188 DOI: 10.1038/emboj.2010.362 |
0.38 |
|
| 2010 |
Cejka P, Plank JL, Bachrati CZ, Hickson ID, Kowalczykowski SC. Rmi1 stimulates decatenation of double Holliday junctions during dissolution by Sgs1-Top3 Nature Structural and Molecular Biology. 17: 1377-1382. PMID 20935631 DOI: 10.1038/Nsmb.1919 |
0.323 |
|
| 2010 |
Chu WK, Hanada K, Kanaar R, Hickson ID. BLM has early and late functions in homologous recombination repair in mouse embryonic stem cells. Oncogene. 29: 4705-14. PMID 20531307 DOI: 10.1038/Onc.2010.214 |
0.456 |
|
| 2010 |
Yang J, Bachrati CZ, Ou J, Hickson ID, Brown GW. Human topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1. The Journal of Biological Chemistry. 285: 21426-36. PMID 20445207 DOI: 10.1074/Jbc.M110.123216 |
0.311 |
|
| 2010 |
Ashton TM, Hickson ID. Yeast as a model system to study RecQ helicase function Dna Repair. 9: 303-314. PMID 20071248 DOI: 10.1016/j.dnarep.2009.12.007 |
0.306 |
|
| 2009 |
Vindigni A, Hickson ID. RecQ helicases: multiple structures for multiple functions? Hfsp Journal. 3: 153-64. PMID 19949442 DOI: 10.2976/1.3079540 |
0.316 |
|
| 2009 |
Bachrati CZ, Hickson ID. Dissolution of double Holliday junctions by the concerted action of BLM and topoisomerase IIIalpha. Methods in Molecular Biology (Clifton, N.J.). 582: 91-102. PMID 19763944 DOI: 10.1007/978-1-60761-340-4_8 |
0.306 |
|
| 2009 |
Hemphill AW, Akkari Y, Newell AH, Schultz RA, Grompe M, North PS, Hickson ID, Jakobs PM, Rennie S, Pauw D, Hejna J, Olson SB, Moses RE. Topo IIIalpha and BLM act within the Fanconi anemia pathway in response to DNA-crosslinking agents. Cytogenetic and Genome Research. 125: 165-75. PMID 19738377 DOI: 10.1159/000230001 |
0.347 |
|
| 2009 |
Chu WK, Hickson ID. RecQ helicases: multifunctional genome caretakers. Nature Reviews. Cancer. 9: 644-54. PMID 19657341 DOI: 10.1038/nrc2682 |
0.333 |
|
| 2009 |
Chan KL, Palmai-Pallag T, Ying S, Hickson ID. Replication stress induces sister-chromatid bridging at fragile site loci in mitosis. Nature Cell Biology. 11: 753-60. PMID 19465922 DOI: 10.1038/ncb1882 |
0.352 |
|
| 2009 |
Payne M, Hickson ID. Genomic instability and cancer: lessons from analysis of Bloom's syndrome. Biochemical Society Transactions. 37: 553-9. PMID 19442250 DOI: 10.1042/BST0370553 |
0.306 |
|
| 2009 |
Mankouri HW, Ngo HP, Hickson ID. Esc2 and Sgs1 act in functionally distinct branches of the homologous recombination repair pathway in Saccharomyces cerevisiae. Molecular Biology of the Cell. 20: 1683-94. PMID 19158388 DOI: 10.1091/mbc.E08-08-0877 |
0.301 |
|
| 2008 |
London TB, Barber LJ, Mosedale G, Kelly GP, Balasubramanian S, Hickson ID, Boulton SJ, Hiom K. FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts. The Journal of Biological Chemistry. 283: 36132-9. PMID 18978354 DOI: 10.1074/Jbc.M808152200 |
0.329 |
|
| 2008 |
Xu D, Guo R, Sobeck A, Bachrati CZ, Yang J, Enomoto T, Brown GW, Hoatlin ME, Hickson ID, Wang W. RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability. Genes & Development. 22: 2843-55. PMID 18923082 DOI: 10.1101/Gad.1708608 |
0.331 |
|
| 2008 |
Selak N, Bachrati CZ, Shevelev I, Dietschy T, van Loon B, Jacob A, Hübscher U, Hoheisel JD, Hickson ID, Stagljar I. The Bloom's syndrome helicase (BLM) interacts physically and functionally with p12, the smallest subunit of human DNA polymerase delta. Nucleic Acids Research. 36: 5166-79. PMID 18682526 DOI: 10.1093/nar/gkn498 |
0.354 |
|
| 2008 |
Popuri V, Bachrati CZ, Muzzolini L, Mosedale G, Costantini S, Giacomini E, Hickson ID, Vindigni A. The Human RecQ helicases, BLM and RECQ1, display distinct DNA substrate specificities. The Journal of Biological Chemistry. 283: 17766-76. PMID 18448429 DOI: 10.1074/jbc.M709749200 |
0.337 |
|
| 2008 |
Bachrati CZ, Hickson ID. RecQ helicases: guardian angels of the DNA replication fork. Chromosoma. 117: 219-33. PMID 18188578 DOI: 10.1007/s00412-007-0142-4 |
0.368 |
|
| 2007 |
Mankouri HW, Hickson ID. The RecQ helicase-topoisomerase III-Rmi1 complex: a DNA structure-specific 'dissolvasome'? Trends in Biochemical Sciences. 32: 538-46. PMID 17980605 DOI: 10.1016/J.TIBS.2007.09.009 |
0.333 |
|
| 2007 |
Hanada K, Budzowska M, Davies SL, van Drunen E, Onizawa H, Beverloo HB, Maas A, Essers J, Hickson ID, Kanaar R. The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks. Nature Structural & Molecular Biology. 14: 1096-104. PMID 17934473 DOI: 10.1038/nsmb1313 |
0.36 |
|
| 2007 |
Rao VA, Conti C, Guirouilh-Barbat J, Nakamura A, Miao ZH, Davies SL, Saccá B, Hickson ID, Bensimon A, Pommier Y. Endogenous γ-H2AX-ATM-Chk2 checkpoint activation in Bloom's syndrome helicase-deficient cells is related to DNA replication arrested forks Molecular Cancer Research. 5: 713-724. PMID 17634426 DOI: 10.1158/1541-7786.MCR-07-0028 |
0.388 |
|
| 2007 |
Davies SL, North PS, Hickson ID. Role for BLM in replication-fork restart and suppression of origin firing after replicative stress Nature Structural and Molecular Biology. 14: 677-679. PMID 17603497 DOI: 10.1038/nsmb1267 |
0.32 |
|
| 2007 |
Chan KL, North PS, Hickson ID. BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges. The Embo Journal. 26: 3397-409. PMID 17599064 DOI: 10.1038/sj.emboj.7601777 |
0.345 |
|
| 2007 |
Hanada K, Hickson ID. Molecular genetics of RecQ helicase disorders. Cellular and Molecular Life Sciences : Cmls. 64: 2306-22. PMID 17571213 DOI: 10.1007/s00018-007-7121-z |
0.3 |
|
| 2007 |
Wu L, Hickson ID. DNA helicases required for homologous recombination and repair of damaged replication forks. Annual Review of Genetics. 40: 279-306. PMID 16856806 DOI: 10.1146/ANNUREV.GENET.40.110405.090636 |
0.324 |
|
| 2006 |
Mankouri HW, Hickson ID. Top3 processes recombination intermediates and modulates checkpoint activity after DNA damage. Molecular Biology of the Cell. 17: 4473-83. PMID 16899506 DOI: 10.1091/MBC.E06-06-0516 |
0.337 |
|
| 2006 |
Bachrati CZ, Hickson ID. Analysis of the DNA unwinding activity of RecQ family helicases. Methods in Enzymology. 409: 86-100. PMID 16793396 DOI: 10.1016/S0076-6879(05)09005-1 |
0.311 |
|
| 2006 |
Ralf C, Hickson ID, Wu L. The Bloom's syndrome helicase can promote the regression of a model replication fork. The Journal of Biological Chemistry. 281: 22839-46. PMID 16766518 DOI: 10.1074/jbc.M604268200 |
0.36 |
|
| 2006 |
Wu L, Bachrati CZ, Ou J, Xu C, Yin J, Chang M, Wang W, Li L, Brown GW, Hickson ID. BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates. Proceedings of the National Academy of Sciences of the United States of America. 103: 4068-73. PMID 16537486 DOI: 10.1073/Pnas.0508295103 |
0.336 |
|
| 2006 |
Spillare EA, Wang XW, von Kobbe C, Bohr VA, Hickson ID, Harris CC. Redundancy of DNA helicases in p53-mediated apoptosis. Oncogene. 25: 2119-23. PMID 16288211 DOI: 10.1038/sj.onc.1209242 |
0.331 |
|
| 2005 |
Win TZ, Mankouri HW, Hickson ID, Wang SW. A role for the fission yeast Rqh1 helicase in chromosome segregation. Journal of Cell Science. 118: 5777-84. PMID 16303848 DOI: 10.1242/Jcs.02694 |
0.401 |
|
| 2005 |
Cheok CF, Bachrati CZ, Chan KL, Ralf C, Wu L, Hickson ID. Roles of the Bloom's syndrome helicase in the maintenance of genome stability. Biochemical Society Transactions. 33: 1456-9. PMID 16246145 DOI: 10.1042/BST20051456 |
0.398 |
|
| 2005 |
Rao VA, Fan AM, Meng L, Doe CF, North PS, Hickson ID, Pommier Y. Phosphorylation of BLM, dissociation from topoisomerase IIIalpha, and colocalization with gamma-H2AX after topoisomerase I-induced replication damage. Molecular and Cellular Biology. 25: 8925-37. PMID 16199871 DOI: 10.1128/MCB.25.20.8925-8937.2005 |
0.368 |
|
| 2005 |
Opresko PL, Mason PA, Podell ER, Lei M, Hickson ID, Cech TR, Bohr VA. POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates. The Journal of Biological Chemistry. 280: 32069-80. PMID 16030011 DOI: 10.1074/Jbc.M505211200 |
0.358 |
|
| 2005 |
Cheok CF, Wu L, Garcia PL, Janscak P, Hickson ID. The Bloom's syndrome helicase promotes the annealing of complementary single-stranded DNA. Nucleic Acids Research. 33: 3932-41. PMID 16024743 DOI: 10.1093/Nar/Gki712 |
0.358 |
|
| 2005 |
Plummer ER, Middleton MR, Jones C, Olsen A, Hickson I, McHugh P, Margison GP, McGown G, Thorncroft M, Watson AJ, Boddy AV, Calvert AH, Harris AL, Newell DR, Curtin NJ. Temozolomide pharmacodynamics in patients with metastatic melanoma: dna damage and activity of repair enzymes O6-alkylguanine alkyltransferase and poly(ADP-ribose) polymerase-1. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 3402-9. PMID 15867241 DOI: 10.1158/1078-0432.Ccr-04-2353 |
0.392 |
|
| 2005 |
Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB, Santarosa M, Dillon KJ, Hickson I, Knights C, Martin NM, Jackson SP, Smith GC, Ashworth A. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature. 434: 917-21. PMID 15829967 DOI: 10.1038/nature03445 |
0.355 |
|
| 2004 |
Hickson I, Zhao Y, Richardson CJ, Green SJ, Martin NM, Orr AI, Reaper PM, Jackson SP, Curtin NJ, Smith GC. Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM. Cancer Research. 64: 9152-9. PMID 15604286 DOI: 10.1158/0008-5472.CAN-04-2727 |
0.31 |
|
| 2004 |
Win TZ, Goodwin A, Hickson ID, Norbury CJ, Wang SW. Requirement for Schizosaccharomyces pombe Top3 in the maintenance of chromosome integrity. Journal of Cell Science. 117: 4769-78. PMID 15340008 DOI: 10.1242/Jcs.01351 |
0.328 |
|
| 2004 |
Jiao R, Bachrati CZ, Pedrazzi G, Kuster P, Petkovic M, Li JL, Egli D, Hickson ID, Stagljar I. Physical and functional interaction between the Bloom's syndrome gene product and the largest subunit of chromatin assembly factor 1. Molecular and Cellular Biology. 24: 4710-9. PMID 15143166 DOI: 10.1128/Mcb.24.11.4710-4719.2004 |
0.374 |
|
| 2004 |
Yang Q, Zhang R, Wang XW, Linke SP, Sengupta S, Hickson ID, Pedrazzi G, Perrera C, Stagljar I, Littman SJ, Modrich P, Harris CC. The mismatch DNA repair heterodimer, hMSH2/6, regulates BLM helicase Oncogene. 23: 3749-3756. PMID 15064730 DOI: 10.1038/Sj.Onc.1207462 |
0.335 |
|
| 2004 |
Davies SL, North PS, Dart A, Lakin ND, Hickson ID. Phosphorylation of the Bloom's Syndrome Helicase and Its Role in Recovery from S-Phase Arrest Molecular and Cellular Biology. 24: 1279-1291. PMID 14729972 DOI: 10.1128/MCB.24.3.1279-1291.2004 |
0.381 |
|
| 2004 |
Wu L, Hickson ID. The Bloom's syndrome helicase suppresses crossing over during homologous recombination. Nature. 426: 870-4. PMID 14685245 DOI: 10.1038/nature02253 |
0.376 |
|
| 2003 |
Sharma S, Sommers JA, Wu L, Bohr VA, Hickson ID, Brosh RM. Stimulation of flap endonuclease-1 by the Bloom's syndrome protein. The Journal of Biological Chemistry. 279: 9847-56. PMID 14688284 DOI: 10.1074/JBC.M309898200 |
0.379 |
|
| 2003 |
Rassool FV, North PS, Mufti GJ, Hickson ID. Constitutive DNA damage is linked to DNA replication abnormalities in Bloom's syndrome cells. Oncogene. 22: 8749-57. PMID 14647470 DOI: 10.1038/sj.onc.1206970 |
0.405 |
|
| 2003 |
Braybrooke JP, Li JL, Wu L, Caple F, Benson FE, Hickson ID. Functional interaction between the Bloom's syndrome helicase and the RAD51 paralog, RAD51L3 (RAD51D). The Journal of Biological Chemistry. 278: 48357-66. PMID 12975363 DOI: 10.1074/jbc.M308838200 |
0.341 |
|
| 2003 |
Pedrazzi G, Bachrati CZ, Selak N, Studer I, Petkovic M, Hickson ID, Jiricny J, Stagljar I. The Bloom's syndrome helicase interacts directly with the human DNA mismatch repair protein hMSH6. Biological Chemistry. 384: 1155-64. PMID 12974384 DOI: 10.1515/BC.2003.128 |
0.385 |
|
| 2003 |
Khakhar RR, Cobb JA, Bjergbaek L, Hickson ID, Gasser SM. RecQ helicases: multiple roles in genome maintenance. Trends in Cell Biology. 13: 493-501. PMID 12946629 DOI: 10.1016/S0962-8924(03)00171-5 |
0.332 |
|
| 2003 |
Bachrati CZ, Hickson ID. RecQ helicases: suppressors of tumorigenesis and premature aging. The Biochemical Journal. 374: 577-606. PMID 12803543 DOI: 10.1042/BJ20030491 |
0.334 |
|
| 2003 |
Hickson ID. RecQ helicases: caretakers of the genome. Nature Reviews. Cancer. 3: 169-78. PMID 12612652 DOI: 10.1038/nrc1012 |
0.35 |
|
| 2003 |
Oakley TJ, Hickson ID. Defending genome integrity during S-phase: putative roles for RecQ helicases and topoisomerase III. Dna Repair. 1: 175-207. PMID 12509252 DOI: 10.1016/S1568-7864(02)00002-2 |
0.308 |
|
| 2002 |
Wu L, Hickson ID. The Bloom's syndrome helicase stimulates the activity of human topoisomerase IIIalpha. Nucleic Acids Research. 30: 4823-9. PMID 12433984 DOI: 10.1093/NAR/GKF611 |
0.355 |
|
| 2002 |
Wu L, Hickson ID. RecQ helicases and cellular responses to DNA damage. Mutation Research. 509: 35-47. PMID 12427530 DOI: 10.1016/S0027-5107(02)00225-7 |
0.372 |
|
| 2002 |
Yang Q, Zhang R, Wang XW, Spillare EA, Linke SP, Subramanian D, Griffith JD, Li JL, Hickson ID, Shen JC, Loeb LA, Mazur SJ, Appella E, Brosh RM, Karmakar P, et al. The processing of Holliday junctions by BLM and WRN helicases is regulated by p53. The Journal of Biological Chemistry. 277: 31980-7. PMID 12080066 DOI: 10.1074/Jbc.M204111200 |
0.316 |
|
| 2002 |
Pascucci B, Maga G, Hübscher U, Bjoras M, Seeberg E, Hickson ID, Villani G, Giordano C, Cellai L, Dogliotti E. Reconstitution of the base excision repair pathway for 7,8-dihydro-8-oxoguanine with purified human proteins. Nucleic Acids Research. 30: 2124-30. PMID 12000832 DOI: 10.1093/NAR/30.10.2124 |
0.307 |
|
| 2002 |
Gaymes TJ, North PS, Brady N, Hickson ID, Mufti GJ, Rassool FV. Increased error-prone non homologous DNA end-joining--a proposed mechanism of chromosomal instability in Bloom's syndrome. Oncogene. 21: 2525-33. PMID 11971187 DOI: 10.1038/sj.onc.1205331 |
0.367 |
|
| 2001 |
Li JL, Harrison RJ, Reszka AP, Brosh RM, Bohr VA, Neidle S, Hickson ID. Inhibition of the Bloom's and Werner's syndrome helicases by G-quadruplex interacting ligands. Biochemistry. 40: 15194-202. PMID 11735402 DOI: 10.1021/Bi011067H |
0.331 |
|
| 2001 |
Pedrazzi G, Perrera C, Blaser H, Kuster P, Marra G, Davies SL, Ryu GH, Freire R, Hickson ID, Jiricny J, Stagljar I. Direct association of Bloom's syndrome gene product with the human mismatch repair protein MLH1 Nucleic Acids Research. 29: 4378-4386. PMID 11691925 DOI: 10.1093/NAR/29.21.4378 |
0.323 |
|
| 2001 |
Chakraverty RK, Kearsey JM, Oakley TJ, Grenon M, de La Torre Ruiz MA, Lowndes NF, Hickson ID. Topoisomerase III acts upstream of Rad53p in the S-phase DNA damage checkpoint. Molecular and Cellular Biology. 21: 7150-62. PMID 11585898 DOI: 10.1128/MCB.21.21.7150-7162.2001 |
0.307 |
|
| 2001 |
Wu L, Hickson ID. RecQ helicases and topoisomerases: components of a conserved complex for the regulation of genetic recombination. Cellular and Molecular Life Sciences : Cmls. 58: 894-901. PMID 11497238 DOI: 10.1007/PL00000909 |
0.33 |
|
| 2001 |
Wang SW, Goodwin A, Hickson ID, Norbury CJ. Involvement of Schizosaccharomyces pombe Srs2 in cellular responses to DNA damage. Nucleic Acids Research. 29: 2963-72. PMID 11452021 DOI: 10.1093/Nar/29.14.2963 |
0.355 |
|
| 2001 |
Mohaghegh P, Karow JK, Brosh RM, Bohr VA, Hickson ID. The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases. Nucleic Acids Research. 29: 2843-9. PMID 11433031 DOI: 10.1093/NAR/29.13.2843 |
0.323 |
|
| 2001 |
Wu L, Davies SL, Levitt NC, Hickson ID. Potential Role for the BLM Helicase in Recombinational Repair via a Conserved Interaction with RAD51 Journal of Biological Chemistry. 276: 19375-19381. PMID 11278509 DOI: 10.1074/jbc.M009471200 |
0.371 |
|
| 2001 |
Mohaghegh P, Hickson ID. DNA helicase deficiencies associated with cancer predisposition and premature ageing disorders. Human Molecular Genetics. 10: 741-6. PMID 11257107 DOI: 10.1093/HMG/10.7.741 |
0.358 |
|
| 2001 |
Constantinou A, Tarsounas M, Karow JK, Brosh RM, Bohr VA, Hickson ID, West SC. Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest. Embo Reports. 1: 80-4. PMID 11256630 DOI: 10.1093/Embo-Reports/Kvd004 |
0.338 |
|
| 2000 |
Brosh RM, Majumdar A, Desai S, Hickson ID, Bohr VA, Seidman MM. Unwinding of a DNA triple helix by the Werner and Bloom syndrome helicases. The Journal of Biological Chemistry. 276: 3024-30. PMID 11110789 DOI: 10.1074/JBC.M006784200 |
0.333 |
|
| 2000 |
Braybrooke JP, Spink KG, Thacker J, Hickson ID. The RAD51 family member, RAD51L3, is a DNA-stimulated ATPase that forms a complex with XRCC2 Journal of Biological Chemistry. 275: 29100-29106. PMID 10871607 DOI: 10.1074/JBC.M002075200 |
0.34 |
|
| 2000 |
Brosh RM, Karow JK, White EJ, Shaw ND, Hickson ID, Bohr VA. Potent inhibition of werner and bloom helicases by DNA minor groove binding drugs. Nucleic Acids Research. 28: 2420-30. PMID 10871376 DOI: 10.1093/NAR/28.12.2420 |
0.381 |
|
| 2000 |
Brosh RM, Li JL, Kenny MK, Karow JK, Cooper MP, Kureekattil RP, Hickson ID, Bohr VA. Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity. The Journal of Biological Chemistry. 275: 23500-8. PMID 10825162 DOI: 10.1074/jbc.M001557200 |
0.336 |
|
| 2000 |
Karow JK, Constantinou A, Li JL, West SC, Hickson ID. The Bloom's syndrome gene product promotes branch migration of holliday junctions. Proceedings of the National Academy of Sciences of the United States of America. 97: 6504-8. PMID 10823897 DOI: 10.1073/Pnas.100448097 |
0.376 |
|
| 1999 |
Goodwin A, Wang SW, Toda T, Norbury C, Hickson ID. Topoisomerase III is essential for accurate nuclear division in Schizosaccharomyces pombe. Nucleic Acids Research. 27: 4050-8. PMID 10497270 DOI: 10.1093/Nar/27.20.4050 |
0.317 |
|
| 1999 |
Chakraverty RK, Hickson ID. Defending genome integrity during DNA replication: a proposed role for RecQ family helicases. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 21: 286-94. PMID 10377891 DOI: 10.1002/(SICI)1521-1878(199904)21:4<286::AID-BIES4>3.0.CO;2-Z |
0.393 |
|
| 1998 |
Sun H, Karow JK, Hickson ID, Maizels N. The Bloom's syndrome helicase unwinds G4 DNA. The Journal of Biological Chemistry. 273: 27587-92. PMID 9765292 DOI: 10.1074/Jbc.273.42.27587 |
0.323 |
|
| 1998 |
Karow JK, Chakraverty RK, Hickson ID. The Bloom's syndrome gene product is a 3'-5' DNA helicase. The Journal of Biological Chemistry. 272: 30611-4. PMID 9388193 DOI: 10.1074/jbc.272.49.30611 |
0.344 |
|
| 1997 |
Rafferty JA, Wibley JEA, Speers P, Hickson I, Margison GP, Moody PCE, Douglas KT. The potential role of glycine-160 of human O6-alkylguanine-DNA alkyltransferase in reaction with O6-benzylguanine as determined by site-directed mutagenesis and molecular modelling comparisons Biochimica Et Biophysica Acta. 1342: 90-102. PMID 9366274 DOI: 10.1016/S0167-4838(97)00095-2 |
0.331 |
|
| 1997 |
Meyer KN, Kjeldsen E, Straub T, Knudsen BR, Hickson ID, Kikuchi A, Kreipe H, Boege F. Cell cycle-coupled relocation of types I and II topoisomerases and modulation of catalytic enzyme activities. The Journal of Cell Biology. 136: 775-88. PMID 9049244 DOI: 10.1083/jcb.136.4.775 |
0.308 |
|
| 1997 |
Aspinwall R, Rothwell DG, Roldan-Arjona T, Anselmino C, Ward CJ, Cheadle JP, Sampson JR, Lindahl T, Harris PC, Hickson ID. Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III Proceedings of the National Academy of Sciences of the United States of America. 94: 109-114. PMID 8990169 DOI: 10.1073/Pnas.94.1.109 |
0.311 |
|
| 1995 |
Walker LJ, Craig RB, Harris AL, Hickson ID. A role for the human DNA repair enzyme HAP1 in cellular protection against DNA damaging agents and hypoxic stress. Nucleic Acids Research. 22: 4884-9. PMID 7800476 DOI: 10.1093/nar/22.23.4884 |
0.308 |
|
| 1993 |
Walker LJ, Robson CN, Black E, Gillespie D, Hickson ID. Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding. Molecular and Cellular Biology. 13: 5370-5376. DOI: 10.1128/MCB.13.9.5370 |
0.304 |
|
| 1989 |
Robson CN, Harris AL, Hickson ID. Defective repair of DNA single- and double-strand breaks in the bleomycin- and X-ray-sensitive Chinese hamster ovary cell mutant, BLM-2. Mutation Research. 217: 93-100. PMID 2465493 DOI: 10.1016/0921-8777(89)90060-8 |
0.309 |
|
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