| Year |
Citation |
Score |
| 2024 |
Kim G, Hou X, Byun WS, Kim G, Jarhad DB, Lee G, Hyun YE, Yu J, Lee CS, Qu S, Warnick E, Gao ZG, Kim JY, Ji S, Shin H, et al. Correction to "Structure-Activity Relationship of Truncated 2,8-Disubstituted-Adenosine Derivatives as Dual A/A Adenosine Receptor Antagonists and Their Cancer Immunotherapeutic Activity". Journal of Medicinal Chemistry. PMID 38259147 DOI: 10.1021/acs.jmedchem.3c02442 |
0.53 |
|
| 2023 |
Kim G, Hou X, Byun WS, Kim G, Jarhad DB, Lee G, Hyun YE, Yu J, Lee CS, Qu S, Warnick E, Gao ZG, Kim JY, Ji S, Shin H, et al. Structure-Activity Relationship of Truncated 2,8-Disubstituted-Adenosine Derivatives as Dual A/A Adenosine Receptor Antagonists and Their Cancer Immunotherapeutic Activity. Journal of Medicinal Chemistry. PMID 37603705 DOI: 10.1021/acs.jmedchem.3c00806 |
0.565 |
|
| 2022 |
Son Y, Kim J, Kim Y, Chi SG, Kim T, Yu J. Discovery of dioxo-benzo[b]thiophene derivatives as potent YAP-TEAD interaction inhibitors for treating breast cancer. Bioorganic Chemistry. 131: 106274. PMID 36434952 DOI: 10.1016/j.bioorg.2022.106274 |
0.327 |
|
| 2022 |
Shiriaeva A, Park D, Kim G, Lee Y, Hou X, Jarhad DB, Kim G, Yu J, Hyun YE, Kim W, Gao ZG, Jacobson KA, Han GW, Stevens RC, Jeong LS, et al. GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for the A Adenosine Receptor. Journal of Medicinal Chemistry. PMID 35977382 DOI: 10.1021/acs.jmedchem.2c00462 |
0.565 |
|
| 2022 |
Park S, Ahn Y, Kim Y, Roh EJ, Lee Y, Han C, Yoo HM, Yu J. Design, Synthesis and Biological Evaluation of 1,3,5-Triazine Derivatives Targeting hA and hA Adenosine Receptor. Molecules (Basel, Switzerland). 27. PMID 35807265 DOI: 10.3390/molecules27134016 |
0.586 |
|
| 2022 |
Abel B, Murakami M, Tosh DK, Yu J, Lusvarghi S, Campbell RG, Gao ZG, Jacobson KA, Ambudkar SV. Interaction of A adenosine receptor ligands with the human multidrug transporter ABCG2. European Journal of Medicinal Chemistry. 231: 114103. PMID 35152062 DOI: 10.1016/j.ejmech.2022.114103 |
0.559 |
|
| 2021 |
Choi H, Jacobson KA, Yu J, Jeong LS. Design and Synthesis of 2,6-Disubstituted-4'-Selenoadenosine-5'-,-Dimethyluronamide Derivatives as Human A Adenosine Receptor Antagonists. Pharmaceuticals (Basel, Switzerland). 14. PMID 33920062 DOI: 10.3390/ph14040363 |
0.603 |
|
| 2020 |
An S, Kim G, Kim HJ, Ahn S, Kim HY, Ko H, Hyun YE, Nguyen M, Jeong J, Liu Z, Han J, Choi H, Yu J, Kim JW, Lee HW, et al. Discovery and Structure-Activity Relationships of Novel Template, Truncated 1'-Homologated Adenosine Derivatives as Pure Dual PPARγ/δ Modulators. Journal of Medicinal Chemistry. PMID 33325691 DOI: 10.1021/acs.jmedchem.0c01874 |
0.589 |
|
| 2020 |
Jung YH, Yu J, Wen Z, Salmaso V, Karcz TP, Phung NB, Chen Z, Duca S, Bennett JM, Dudas S, Salvemini D, Gao ZG, Cook DN, Jacobson KA. Exploration of Alternative Scaffolds for P2Y Receptor Antagonists Containing a Biaryl Core. Journal of Medicinal Chemistry. PMID 32787142 DOI: 10.1021/Acs.Jmedchem.0C00745 |
0.62 |
|
| 2020 |
Mufti F, Jung YH, Giancotti LA, Yu J, Chen Z, Phung NB, Jacobson KA, Salvemini D. P2Y Receptor Antagonists Reverse Chronic Neuropathic Pain in a Mouse Model. Acs Medicinal Chemistry Letters. 11: 1281-1286. PMID 32551012 DOI: 10.1021/Acsmedchemlett.0C00115 |
0.515 |
|
| 2019 |
An S, Yu J, Choi H, Ko H, Ahn S, Shin JC, Pyo JJ, Jeong LS, Noh M. Selenium bioisosteric replacement of adenosine derivatives promoting adiponectin secretion increases the binding affinity to peroxisome proliferator-activated receptor δ. Bioorganic & Medicinal Chemistry. 115226. PMID 31806266 DOI: 10.1016/j.bmc.2019.115226 |
0.48 |
|
| 2018 |
Yu J, Mannes P, Jung YH, Ciancetta A, Bitant A, Lieberman DI, Khaznadar S, Auchampach JA, Gao ZG, Jacobson KA. Structure activity relationship of 2-arylalkynyl-adenine derivatives as human A adenosine receptor antagonists. Medchemcomm. 9: 1920-1932. PMID 30568760 DOI: 10.1039/C8Md00317C |
0.632 |
|
| 2018 |
Yu J, Kim G, Jarhad DB, Lee HW, Lee J, Park CW, Ha H, Jeong LS. Correlation study between A adenosine receptor binding affinity and anti-renal interstitial fibrosis activity of truncated adenosine derivatives. Archives of Pharmacal Research. PMID 30264323 DOI: 10.1007/s12272-018-1079-2 |
0.386 |
|
| 2018 |
Yoon JS, Jarhad DB, Kim G, Nayak A, Zhao LX, Yu J, Kim HR, Lee JY, Mulamoottil VA, Chandra G, Byun WS, Lee SK, Kim YC, Jeong LS. Design, synthesis and anticancer activity of fluorocyclopentenyl-purines and - pyrimidines. European Journal of Medicinal Chemistry. 155: 406-417. PMID 29906687 DOI: 10.1016/j.ejmech.2018.06.003 |
0.465 |
|
| 2018 |
Yu J, Ciancetta A, Dudas S, Duca S, Lottermoser J, Jacobson KA. Structure-Guided Modification of Heterocyclic Antagonists of the P2Y Receptor. Journal of Medicinal Chemistry. PMID 29767967 DOI: 10.1021/Acs.Jmedchem.8B00168 |
0.606 |
|
| 2017 |
Duroux R, Ciancetta A, Mannes P, Yu J, Boyapati S, Gizewski E, Yous S, Ciruela F, Auchampach JA, Gao ZG, Jacobson KA. Bitopic fluorescent antagonists of the A2A adenosine receptor based on pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine functionalized congeners. Medchemcomm. 8: 1659-1667. PMID 29250307 DOI: 10.1039/C7Md00247E |
0.61 |
|
| 2017 |
Yu J, Ahn S, Kim HJ, Lee M, Ahn S, Kim J, Jin SH, Lee E, Kim G, Cheong JH, Jacobson KA, Jeong LS, Noh M. Polypharmacology of N6-(3-iodobenzyl)adenosine-5'-N-methyluronamide (IB-MECA) and Related A3 Adenosine Receptor Ligands: Peroxisome Proliferator Activated Receptor (PPAR) γ Partial Agonist and PPAR δ Antagonist Activity Suggests Their Anti-diabetic Potential. Journal of Medicinal Chemistry. PMID 28799755 DOI: 10.1021/Acs.Jmedchem.7B00805 |
0.512 |
|
| 2017 |
Yu J, Zhao LX, Park J, Lee HW, Sahu PK, Cui M, Moss SM, Hammes E, Warnick E, Gao ZG, Noh M, Choi S, Ahn HC, Choi J, Jacobson KA, et al. N6-Substituted-5'-N-Methylcarbamoyl-4'-selenoadenosines as Potent and Selective A3 Adenosine Receptor Agonists with Unusual Sugar Puckering and Nucleobase Orientation. Journal of Medicinal Chemistry. PMID 28380296 DOI: 10.1021/Acs.Jmedchem.7B00241 |
0.535 |
|
| 2016 |
Qu S, Mulamoottil VA, Nayak A, Ryu S, Hou X, Song J, Yu J, Sahu PK, Zhao LX, Choi S, Lee SK, Jeong LS. Design, synthesis, and anticancer activity of C8-substituted-4'-thionucleosides as potential HSP90 inhibitors. Bioorganic & Medicinal Chemistry. PMID 27283788 DOI: 10.1016/j.bmc.2016.05.041 |
0.315 |
|
| 2015 |
Ahn S, Yi S, Seo WJ, Lee MJ, Song YK, Baek SY, Yu J, Hong SH, Lee J, Shin DW, Jeong LS, Noh M. A cannabinoid receptor agonist N-arachidonoyl dopamine inhibits adipocyte differentiation in human mesenchymal stem cells. Biomolecules & Therapeutics. 23: 218-24. PMID 25995819 DOI: 10.4062/biomolther.2014.137 |
0.406 |
|
| 2015 |
Alexander V, Song J, Yu J, Choi JH, Kim JH, Lee SK, Choi WJ, Jeong LS. Synthesis and biological evaluation of 2'-substituted-4'-selenoribofuranosyl pyrimidines as antitumor agents. Archives of Pharmacal Research. 38: 966-72. PMID 25239109 DOI: 10.1007/s12272-014-0466-6 |
0.325 |
|
| 2014 |
Kim JH, Yu J, Alexander V, Choi JH, Song J, Lee HW, Kim HO, Choi J, Lee SK, Jeong LS. Structure-activity relationships of 2'-modified-4'-selenoarabinofuranosyl-pyrimidines as anticancer agents. European Journal of Medicinal Chemistry. 83: 208-25. PMID 24956556 DOI: 10.1016/j.ejmech.2014.06.031 |
0.319 |
|
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