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Janarthanan Krishnamoorthy - Publications

Affiliations: 
Chemistry and Biophysics University of Michigan, Ann Arbor, Ann Arbor, MI 
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22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Sarkar D, Saha S, Krishnamoorthy J, Bhunia A. Application of singular value decomposition analysis: Insights into the complex mechanisms of amyloidogenesis. Biophysical Chemistry. 306: 107157. PMID 38184980 DOI: 10.1016/j.bpc.2023.107157  0.33
2023 Won T, Mohid SA, Choi J, Kim M, Krishnamoorthy J, Biswas I, Bhunia A, Lee D. The role of hydrophobic patches of de novo designed MSI-78 and VG16KRKP antimicrobial peptides on fragmenting model bilayer membranes. Biophysical Chemistry. 296: 106981. PMID 36871366 DOI: 10.1016/j.bpc.2023.106981  0.646
2020 Bera S, Gayen N, Mohid SA, Bhattacharyya D, Krishnamoorthy J, Sarkar D, Choi J, Sahoo N, Mandal AK, Lee D, Bhunia A. Comparison of Synthetic Neuronal Model Membrane Mimics in Amyloid Aggregation at Atomic Resolution. Acs Chemical Neuroscience. PMID 32492332 DOI: 10.1021/Acschemneuro.0C00166  0.721
2020 Krishnamoorthy GK, Alluvada P, Hameed Mohammed Sherieff S, Kwa T, Krishnamoorthy J. Isothermal titration calorimetry and surface plasmon resonance analysis using the dynamic approach. Biochemistry and Biophysics Reports. 21: 100712. PMID 31890903 DOI: 10.1016/J.Bbrep.2019.100712  0.326
2019 Brender JR, Ghosh A, Kotler SA, Krishnamoorthy J, Bera S, Morris V, Sil TB, Garai K, Reif B, Bhunia A, Ramamoorthy A. Probing transient non-native states in amyloid beta fiber elongation by NMR. Chemical Communications (Cambridge, England). PMID 30917192 DOI: 10.1039/C9Cc01067J  0.735
2019 Bhattacharyya D, Mohite GM, Krishnamoorthy J, Gayen N, Mehera S, Navalkar A, Kotler SA, Ratha BN, Ghosh A, Kumar R, Garai K, Mandal AK, Maji SK, Bhunia A. Lipopolysaccharide from Gut Microbiota Modulates α-Synuclein Aggregation and Alters its Biological Function. Acs Chemical Neuroscience. PMID 30855940 DOI: 10.1021/Acschemneuro.8B00733  0.715
2018 Brender JR, Krishnamoorthy J, Ghosh A, Bhunia A. Binding Moiety Mapping by Saturation Transfer Difference NMR. Methods in Molecular Biology (Clifton, N.J.). 1824: 49-65. PMID 30039401 DOI: 10.1007/978-1-4939-8630-9_4  0.599
2017 Ghosh A, Pradhan N, Bera S, Datta A, Krishnamoorthy J, Jana NR, Bhunia A. Inhibition and Degradation of Amyloid Beta (Aβ40) Fibrillation by Designed Small Pep-tide: A Combined Spectroscopy, Microscopy and Cell Toxicity Study. Acs Chemical Neuroscience. PMID 28061031 DOI: 10.1021/Acschemneuro.6B00349  0.517
2015 Kotler SA, Brender JR, Vivekanandan S, Suzuki Y, Yamamoto K, Monette M, Krishnamoorthy J, Walsh P, Cauble M, Holl MM, Marsh EN, Ramamoorthy A. High-resolution NMR characterization of low abundance oligomers of amyloid-β without purification. Scientific Reports. 5: 11811. PMID 26138908 DOI: 10.1038/Srep11811  0.739
2015 Brender JR, Krishnamoorthy J, Sciacca MF, Vivekanandan S, D'Urso L, Chen J, La Rosa C, Ramamoorthy A. Probing the sources of the apparent irreproducibility of amyloid formation: drastic changes in kinetics and a switch in mechanism due to micellelike oligomer formation at critical concentrations of IAPP. The Journal of Physical Chemistry. B. 119: 2886-96. PMID 25645610 DOI: 10.1021/Jp511758W  0.764
2014 DeToma AS, Krishnamoorthy J, Nam Y, Lee HJ, Brender JR, Kochi A, Lee D, Onnis V, Congiu C, Manfredini S, Vertuani S, Balboni G, Ramamoorthy A, Lim MH. Synthetic Flavonoids, Aminoisoflavones: Interaction and Reactivity with Metal-Free and Metal-Associated Amyloid-β Species. Chemical Science. 5: 4851-4862. PMID 25383163 DOI: 10.1039/C4Sc01531B  0.768
2014 Ghosh A, Kar RK, Jana J, Saha A, Jana B, Krishnamoorthy J, Kumar D, Ghosh S, Chatterjee S, Bhunia A. Indolicidin targets duplex DNA: structural and mechanistic insight through a combination of spectroscopy and microscopy. Chemmedchem. 9: 2052-8. PMID 25044630 DOI: 10.1002/Cmdc.201402215  0.309
2014 Yesuvadian R, Krishnamoorthy J, Ramamoorthy A, Bhunia A. Potent γ-secretase inhibitors/modulators interact with amyloid-β fibrils but do not inhibit fibrillation: a high-resolution NMR study. Biochemical and Biophysical Research Communications. 447: 590-5. PMID 24747079 DOI: 10.1016/J.Bbrc.2014.04.041  0.609
2014 Lee S, Zheng X, Krishnamoorthy J, Savelieff MG, Park HM, Brender JR, Kim JH, Derrick JS, Kochi A, Lee HJ, Kim C, Ramamoorthy A, Bowers MT, Lim MH. Rational design of a structural framework with potential use to develop chemical reagents that target and modulate multiple facets of Alzheimer's disease. Journal of the American Chemical Society. 136: 299-310. PMID 24397771 DOI: 10.1021/Ja409801P  0.711
2013 Lee DK, Brender JR, Sciacca MF, Krishnamoorthy J, Yu C, Ramamoorthy A. Lipid composition-dependent membrane fragmentation and pore-forming mechanisms of membrane disruption by pexiganan (MSI-78). Biochemistry. 52: 3254-63. PMID 23590672 DOI: 10.1021/Bi400087N  0.687
2013 Brender JR, Krishnamoorthy J, Messina GM, Deb A, Vivekanandan S, La Rosa C, Penner-Hahn JE, Ramamoorthy A. Zinc stabilization of prefibrillar oligomers of human islet amyloid polypeptide. Chemical Communications (Cambridge, England). 49: 3339-41. PMID 23505632 DOI: 10.1039/C3Cc40383A  0.702
2013 Suzuki Y, Brender JR, Soper MT, Krishnamoorthy J, Zhou Y, Ruotolo BT, Kotov NA, Ramamoorthy A, Marsh EN. Resolution of oligomeric species during the aggregation of Aβ1-40 using (19)F NMR. Biochemistry. 52: 1903-12. PMID 23445400 DOI: 10.1021/Bi400027Y  0.73
2013 Brender JR, Krishnamoorthy J, Sciacca MF, Vivekanandan S, Ramamoorthy A. Divergent Mechanisms in Amyloid Formation Controlled by Critical Points Biophysical Journal. 104: 51a. DOI: 10.1016/J.Bpj.2012.11.320  0.731
2012 Krishnamoorthy J, Brender JR, Vivekanandan S, Jahr N, Ramamoorthy A. Side-chain dynamics reveals transient association of Aβ(1-40) monomers with amyloid fibers. The Journal of Physical Chemistry. B. 116: 13618-23. PMID 23116141 DOI: 10.1021/Jp305279W  0.732
2012 Brender JR, Subramanian V, Krishnamoorthy J, Sciacca MF, Ramamoorthy A. Tracking Conformational Changes during Amyloidogenesis in Real-Time at Atomic-Resolution by NMR Biophysical Journal. 102: 242a. DOI: 10.1016/J.Bpj.2011.11.1334  0.735
2010 Krishnamoorthy J, Yu VC, Mok YK. Auto-FACE: an NMR based binding site mapping program for fast chemical exchange protein-ligand systems. Plos One. 5: e8943. PMID 20174626 DOI: 10.1371/Journal.Pone.0008943  0.315
2010 Bernardo PH, Sivaraman T, Wan KF, Xu J, Krishnamoorthy J, Song CM, Tian L, Chin JS, Lim DS, Mok HY, Yu VC, Tong JC, Chai CL. Structural insights into the design of small molecule inhibitors that selectively antagonize Mcl-1. Journal of Medicinal Chemistry. 53: 2314-8. PMID 20158203 DOI: 10.1021/Jm901469P  0.313
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