| Year |
Citation |
Score |
| 2020 |
Boero G, Porcu P, Morrow AL. Pleiotropic actions of allopregnanolone underlie therapeutic benefits in stress-related disease. Neurobiology of Stress. 12: 100203. PMID 31879693 DOI: 10.1016/J.Ynstr.2019.100203 |
0.77 |
|
| 2019 |
Morrow AL, Boero G, Porcu P. A Rationale for Allopregnanolone Treatment of Alcohol Use Disorders: Basic and Clinical Studies. Alcoholism, Clinical and Experimental Research. PMID 31782169 DOI: 10.1111/Acer.14253 |
0.759 |
|
| 2019 |
Pisu MG, Boero G, Garau A, Casula C, Cisci S, Biggio F, Concas A, Follesa P, Maciocco E, Porcu P, Serra M. Are preconceptional stressful experiences crucial elements for the aetiology of autism spectrum disorder? Insights from an animal model. Neuropharmacology. 157: 107686. PMID 31247268 DOI: 10.1016/J.Neuropharm.2019.107686 |
0.75 |
|
| 2018 |
Boero G, Pisu MG, Biggio F, Muredda L, Carta G, Banni S, Paci E, Follesa P, Concas A, Porcu P, Serra M. Impaired glucocorticoid-mediated HPA axis negative feedback induced by juvenile social isolation in male rats. Neuropharmacology. 133: 242-253. PMID 29407214 DOI: 10.1016/J.Neuropharm.2018.01.045 |
0.764 |
|
| 2018 |
Boero G, Biggio F, Pisu MG, Locci V, Porcu P, Serra M. Combined effect of gestational stress and postpartum stress on maternal care in rats. Physiology & Behavior. 184: 172-178. PMID 29179996 DOI: 10.1016/J.Physbeh.2017.11.027 |
0.735 |
|
| 2017 |
Beattie MC, Reguyal CS, Porcu P, Daunais JB, Grant KA, Morrow AL. Neuroactive Steroid (3α,5α)3-hydroxypregnan-20-one (3α,5α-THP) and Pro-inflammatory Cytokine MCP-1 Levels in Hippocampus CA1 are Correlated with Voluntary Ethanol Consumption in Cynomolgus Monkey. Alcoholism, Clinical and Experimental Research. PMID 29112774 DOI: 10.1111/Acer.13545 |
0.718 |
|
| 2017 |
Pisu MG, Boero G, Biggio F, Garau A, Corda D, Congiu M, Concas A, Porcu P, Serra M. Juvenile social isolation affects maternal care in rats: involvement of allopregnanolone. Psychopharmacology. PMID 28623385 DOI: 10.1007/S00213-017-4661-2 |
0.746 |
|
| 2017 |
Jimenez VA, Porcu P, Morrow AL, Grant KA. Adaptations in Basal and Hypothalamic-Pituitary-Adrenal-Activated Deoxycorticosterone Responses Following Ethanol Self-administration in Cynomolgus Monkeys. Frontiers in Endocrinology. 8: 19. PMID 28220108 DOI: 10.3389/Fendo.2017.00019 |
0.613 |
|
| 2016 |
Porcu P, Lallai V, Locci A, Catzeddu S, Serra V, Pisu MG, Serra M, Dazzi L, Concas A. Changes in stress-stimulated allopregnanolone levels induced by neonatal estradiol treatment are associated with enhanced dopamine release in adult female rats: reversal by progesterone administration. Psychopharmacology. PMID 28013353 DOI: 10.1007/S00213-016-4511-7 |
0.365 |
|
| 2016 |
Porcu P, O'Buckley TK, Lopez MF, Becker HC, Miles MF, Williams RW, Morrow AL. Initial genetic dissection of serum neuroactive steroids following chronic intermittent ethanol across BXD mouse strains. Alcohol (Fayetteville, N.Y.). PMID 27884493 DOI: 10.1016/J.Alcohol.2016.07.011 |
0.571 |
|
| 2016 |
Locci A, Porcu P, Talani G, Santoru F, Berretti R, Giunti E, Licheri V, Sanna E, Concas A. Neonatal estradiol exposure to female rats changes GABAA receptor expression and function, and spatial learning during adulthood. Hormones and Behavior. PMID 27769760 DOI: 10.1016/J.Yhbeh.2016.10.005 |
0.398 |
|
| 2016 |
Concas A, Imperatore R, Santoru F, Locci A, Porcu P, Cristino L, Pierobon P. Immunochemical Localization of GABAA Receptor Subunits in the Freshwater Polyp Hydra vulgaris (Cnidaria, Hydrozoa). Neurochemical Research. PMID 27450241 DOI: 10.1007/S11064-016-2010-1 |
0.322 |
|
| 2016 |
Pisu MG, Garau A, Boero G, Biggio F, Pibiri V, Dore R, Locci V, Paci E, Porcu P, Serra M. Sex differences in the outcome of juvenile social isolation on HPA axis function in rats. Neuroscience. 320: 172-82. PMID 26868968 DOI: 10.1016/J.Neuroscience.2016.02.009 |
0.762 |
|
| 2016 |
Werner DF, Porcu P, Boyd KN, O'Buckley TK, Carter JM, Kumar S, Morrow AL. Ethanol-induced GABAA receptor alpha4 subunit plasticity involves phosphorylation and neuroactive steroids. Molecular and Cellular Neurosciences. PMID 26805653 DOI: 10.1016/J.Mcn.2016.01.002 |
0.784 |
|
| 2016 |
Pisu MG, Garau A, Boero G, Biggio F, Pibiri V, Dore R, Locci V, Paci E, Porcu P, Serra M. Sex differences in the outcome of juvenile social isolation on HPA axis function in rats Neuroscience. 320: 172-182. DOI: 10.1016/j.neuroscience.2016.02.009 |
0.72 |
|
| 2015 |
Porcu P, Barron AM, Frye CA, Walf AA, Yang SY, He XY, Morrow AL, Panzica GC, Melcangi RC. Neurosteroidogenesis today: Novel targets for neuroactive steroid synthesis and action and their relevance for translational research. Journal of Neuroendocrinology. PMID 26681259 DOI: 10.1111/Jne.12351 |
0.547 |
|
| 2015 |
Beattie MC, Maldonado-Devincci AM, Porcu P, O'Buckley TK, Daunais JB, Grant KA, Morrow AL. Voluntary ethanol consumption reduces GABAergic neuroactive steroid (3α,5α)3-hydroxypregnan-20-one (3α,5α-THP) in the amygdala of the cynomolgus monkey. Addiction Biology. PMID 26625954 DOI: 10.1111/Adb.12326 |
0.773 |
|
| 2014 |
Porcu P, Morrow AL. Divergent neuroactive steroid responses to stress and ethanol in rat and mouse strains: relevance for human studies. Psychopharmacology. 231: 3257-72. PMID 24770626 DOI: 10.1007/S00213-014-3564-8 |
0.591 |
|
| 2014 |
Cook JB, Werner DF, Maldonado-Devincci AM, Leonard MN, Fisher KR, O'Buckley TK, Porcu P, McCown TJ, Besheer J, Hodge CW, Morrow AL. Overexpression of the steroidogenic enzyme cytochrome P450 side chain cleavage in the ventral tegmental area increases 3α,5α-THP and reduces long-term operant ethanol self-administration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 5824-34. PMID 24760842 DOI: 10.1523/Jneurosci.4733-13.2014 |
0.754 |
|
| 2014 |
Santoru F, Berretti R, Locci A, Porcu P, Concas A. Decreased allopregnanolone induced by hormonal contraceptives is associated with a reduction in social behavior and sexual motivation in female rats. Psychopharmacology. 231: 3351-64. PMID 24728651 DOI: 10.1007/S00213-014-3539-9 |
0.32 |
|
| 2014 |
Porcu P, Locci A, Santoru F, Berretti R, Morrow AL, Concas A. Failure of acute ethanol administration to alter cerebrocortical and hippocampal allopregnanolone levels in C57BL/6J and DBA/2J mice. Alcoholism, Clinical and Experimental Research. 38: 948-58. PMID 24428156 DOI: 10.1111/Acer.12329 |
0.585 |
|
| 2014 |
Berretti R, Santoru F, Locci A, Sogliano C, Calza A, Choleris E, Porcu P, Concas A. Neonatal exposure to estradiol decreases hypothalamic allopregnanolone concentrations and alters agonistic and sexual but not affective behavior in adult female rats. Hormones and Behavior. 65: 142-53. PMID 24368289 DOI: 10.1016/J.Yhbeh.2013.12.009 |
0.354 |
|
| 2012 |
Porcu P, Mostallino MC, Sogliano C, Santoru F, Berretti R, Concas A. Long-term administration with levonorgestrel decreases allopregnanolone levels and alters GABA(A) receptor subunit expression and anxiety-like behavior. Pharmacology, Biochemistry, and Behavior. 102: 366-72. PMID 22634062 DOI: 10.1016/J.Pbb.2012.05.011 |
0.381 |
|
| 2012 |
Girdler SS, Lindgren M, Porcu P, Rubinow DR, Johnson JL, Morrow AL. A history of depression in women is associated with an altered GABAergic neuroactive steroid profile. Psychoneuroendocrinology. 37: 543-53. PMID 21890277 DOI: 10.1016/J.Psyneuen.2011.08.004 |
0.483 |
|
| 2012 |
Berretti R, Santoru F, Porcu P, Loche L, Corona A, Biggio G, Concas A. P.2.011 Decreased levels of allopregnanolone induced by oral contraceptives are associated with a reduction in social behaviour and sexual motivation in rats European Neuropsychopharmacology. 22. DOI: 10.1016/S0924-977X(12)70043-3 |
0.317 |
|
| 2011 |
Porcu P, O'Buckley TK, Song SC, Harenza JL, Lu L, Wang X, Williams RW, Miles MF, Morrow AL. Genetic analysis of the neurosteroid deoxycorticosterone and its relation to alcohol phenotypes: identification of QTLs and downstream gene regulation. Plos One. 6: e18405. PMID 21494628 DOI: 10.1371/Journal.Pone.0018405 |
0.579 |
|
| 2010 |
Porcu P, O'Buckley TK, Alward SE, Song SC, Grant KA, de Wit H, Leslie Morrow A. Differential effects of ethanol on serum GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in mice, rats, cynomolgus monkeys, and humans. Alcoholism, Clinical and Experimental Research. 34: 432-42. PMID 20028362 DOI: 10.1111/J.1530-0277.2009.01123.X |
0.402 |
|
| 2010 |
Boyd KN, Kumar S, O'Buckley TK, Porcu P, Morrow AL. Ethanol induction of steroidogenesis in rat adrenal and brain is dependent upon pituitary ACTH release and de novo adrenal StAR synthesis. Journal of Neurochemistry. 112: 784-96. PMID 20021565 DOI: 10.1111/J.1471-4159.2009.06509.X |
0.744 |
|
| 2009 |
Morrow AL, Biggio G, Serra M, Becker HC, Lopez MF, Porcu P, Alward SE, O'Buckley TK. The role of neuroactive steroids in ethanol/stress interactions: proceedings of symposium VII at the Volterra conference on alcohol and stress, May 2008. Alcohol (Fayetteville, N.Y.). 43: 521-30. PMID 19913195 DOI: 10.1016/J.Alcohol.2009.04.002 |
0.626 |
|
| 2009 |
Kumar S, Porcu P, Werner DF, Matthews DB, Diaz-Granados JL, Helfand RS, Morrow AL. The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress. Psychopharmacology. 205: 529-64. PMID 19455309 DOI: 10.1007/S00213-009-1562-Z |
0.765 |
|
| 2009 |
Marx CE, Keefe RS, Buchanan RW, Hamer RM, Kilts JD, Bradford DW, Strauss JL, Naylor JC, Payne VM, Lieberman JA, Savitz AJ, Leimone LA, Dunn L, Porcu P, Morrow AL, et al. Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1885-903. PMID 19339966 DOI: 10.1038/Npp.2009.26 |
0.625 |
|
| 2009 |
Porcu P, O'Buckley TK, Alward SE, Marx CE, Shampine LJ, Girdler SS, Morrow AL. Simultaneous quantification of GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in human and rat serum. Steroids. 74: 463-73. PMID 19171160 DOI: 10.1016/J.Steroids.2008.12.015 |
0.621 |
|
| 2008 |
Porcu P, O'Buckley TK, Leslie Morrow A, Adinoff B. Differential hypothalamic-pituitary-adrenal activation of the neuroactive steroids pregnenolone sulfate and deoxycorticosterone in healthy controls and alcohol-dependent subjects. Psychoneuroendocrinology. 33: 214-26. PMID 18096321 DOI: 10.1016/J.Psyneuen.2007.11.003 |
0.39 |
|
| 2008 |
Morrow A, Boyd K, Porcu P. S.24.05 Neurosteroids mediate alcohol sensitivity: mechanisms and therapeutic relevance European Neuropsychopharmacology. 18: S192. DOI: 10.1016/S0924-977X(08)70210-4 |
0.604 |
|
| 2007 |
Sassoè-Pognetto M, Follesa P, Panzanelli P, Perazzini AZ, Porcu P, Sogliano C, Cherchi C, Concas A. Fluctuations in brain concentrations of neurosteroids are not associated to changes in gephyrin levels. Brain Research. 1169: 1-8. PMID 17698049 DOI: 10.1016/J.Brainres.2007.06.057 |
0.324 |
|
| 2006 |
Morrow AL, Porcu P, Boyd KN, Grant KA. Hypothalamic-pituitary-adrenal axis modulation of GABAergic neuroactive steroids influences ethanol sensitivity and drinking behavior. Dialogues in Clinical Neuroscience. 8: 463-77. PMID 17290803 |
0.747 |
|
| 2006 |
Porcu P, Rogers LS, Morrow AL, Grant KA. Plasma pregnenolone levels in cynomolgus monkeys following pharmacological challenges of the hypothalamic-pituitary-adrenal axis. Pharmacology, Biochemistry, and Behavior. 84: 618-27. PMID 16790266 DOI: 10.1016/J.Pbb.2006.05.004 |
0.602 |
|
| 2006 |
Concas A, Sogliano C, Porcu P, Marra C, Brundu A, Biggio G. Neurosteroids in nicotine and morphine dependence. Psychopharmacology. 186: 281-92. PMID 16133140 DOI: 10.1007/S00213-005-0111-7 |
0.319 |
|
| 2006 |
Porcu P, Grant KA, Green HL, Rogers LS, Morrow AL. Hypothalamic-pituitary-adrenal axis and ethanol modulation of deoxycorticosterone levels in cynomolgus monkeys. Psychopharmacology. 186: 293-301. PMID 16133132 DOI: 10.1007/S00213-005-0132-2 |
0.599 |
|
| 2005 |
Shannon EE, Porcu P, Purdy RH, Grant KA. Characterization of the discriminative stimulus effects of the neuroactive steroid pregnanolone in DBA/2J and C57BL/6J inbred mice. The Journal of Pharmacology and Experimental Therapeutics. 314: 675-85. PMID 15857945 DOI: 10.1124/Jpet.104.082644 |
0.306 |
|
| 2004 |
Porcu P, Grant KA. Discriminative stimulus effects of ethanol in rats using a three-choice ethanol-midazolam-water discrimination. Behavioural Pharmacology. 15: 555-67. PMID 15577454 DOI: 10.1097/00008877-200412000-00004 |
0.417 |
|
| 2004 |
Porcu P, Sogliano C, Ibba C, Piredda M, Tocco S, Marra C, Purdy RH, Biggio G, Concas A. Failure of gamma-hydroxybutyric acid both to increase neuroactive steroid concentrations in adrenalectomized-orchiectomized rats and to induce tolerance to its steroidogenic effect in intact animals. Brain Research. 1012: 160-8. PMID 15158173 DOI: 10.1016/J.Brainres.2004.03.059 |
0.418 |
|
| 2003 |
Porcu P, Sogliano C, Cinus M, Purdy RH, Biggio G, Concas A. Nicotine-induced changes in cerebrocortical neuroactive steroids and plasma corticosterone concentrations in the rat. Pharmacology, Biochemistry, and Behavior. 74: 683-90. PMID 12543235 DOI: 10.1016/S0091-3057(02)01065-1 |
0.327 |
|
| 2002 |
Follesa P, Porcu P, Sogliano C, Cinus M, Biggio F, Mancuso L, Mostallino MC, Paoletti AM, Purdy RH, Biggio G, Concas A. Changes in GABAA receptor gamma 2 subunit gene expression induced by long-term administration of oral contraceptives in rats. Neuropharmacology. 42: 325-36. PMID 11897111 DOI: 10.1016/S0028-3908(01)00187-3 |
0.37 |
|
| 2001 |
Follesa P, Concas A, Porcu P, Sanna E, Serra M, Mostallino MC, Purdy RH, Biggio G. Role of allopregnanolone in regulation of GABA(A) receptor plasticity during long-term exposure to and withdrawal from progesterone. Brain Research. Brain Research Reviews. 37: 81-90. PMID 11744076 DOI: 10.1016/S0165-0173(01)00125-4 |
0.345 |
|
| 2000 |
Concas A, Porcu P, Sogliano C, Serra M, Purdy RH, Biggio G. Caffeine-induced increases in the brain and plasma concentrations of neuroactive steroids in the rat. Pharmacology, Biochemistry, and Behavior. 66: 39-45. PMID 10837842 DOI: 10.1016/S0091-3057(00)00237-9 |
0.317 |
|
| 1998 |
Concas A, Mostallino MC, Porcu P, Follesa P, Barbaccia ML, Trabucchi M, Purdy RH, Grisenti P, Biggio G. Role of brain allopregnanolone in the plasticity of gamma-aminobutyric acid type A receptor in rat brain during pregnancy and after delivery. Proceedings of the National Academy of Sciences of the United States of America. 95: 13284-9. PMID 9789080 DOI: 10.1073/Pnas.95.22.13284 |
0.337 |
|
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