Year |
Citation |
Score |
2020 |
Csibi A, Yang B, Chutake Y, Yuan K, Mayo M, Campbell V, McDonald A, Rusin S, Sharma K, Kamadurai H, Li H, Sintchak M, Zhu S, Townson S, Slavin A, et al. Abstract LB-088: A STAT3 selective targeted protein degrader decreases the immunesuppressive tumor microenvironment and drives antitumor activity in preclinical models Cancer Research. 80. DOI: 10.1158/1538-7445.Am2020-Lb-088 |
0.316 |
|
2019 |
Kelleher JF, Campbell V, Chen J, Gollob J, Ji N, Kamadurai H, Klaus C, Li H, Loh C, McDonald A, Rong H, Rusin S, Sharma K, Vigil D, Walker D, et al. Abstract LB-272: KYM-001, a first-in-class oral IRAK4 protein degrader, induces tumor regression in xenograft models of MYD88-mutant ABC DLBCL alone and in combination with BTK inhibition Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Lb-272 |
0.362 |
|
2018 |
Liu JJ, Sharma K, Zangrandi L, Chen C, Humphrey SJ, Chiu YT, Spetea M, Liu-Chen LY, Schwarzer C, Mann M. In vivo brain GPCR signaling elucidated by phosphoproteomics. Science (New York, N.Y.). 360. PMID 29930108 DOI: 10.1126/Science.Aao4927 |
0.597 |
|
2016 |
Marakalala MJ, Raju RM, Sharma K, Zhang YJ, Eugenin EA, Prideaux B, Daudelin IB, Chen PY, Booty MG, Kim JH, Eum SY, Via LE, Behar SM, Barry CE, Mann M, et al. Inflammatory signaling in human tuberculosis granulomas is spatially organized. Nature Medicine. PMID 27043495 DOI: 10.1038/Nm.4073 |
0.51 |
|
2015 |
Sharma K, Schmitt S, Bergner CG, Tyanova S, Kannaiyan N, Manrique-Hoyos N, Kongi K, Cantuti L, Hanisch UK, Philips MA, Rossner MJ, Mann M, Simons M. Cell type- and brain region-resolved mouse brain proteome. Nature Neuroscience. PMID 26523646 DOI: 10.1038/Nn.4160 |
0.577 |
|
2015 |
Zeigerer A, Bogorad RL, Sharma K, Gilleron J, Seifert S, Sales S, Berndt N, Bulik S, Marsico G, D'Souza RC, Lakshmanaperumal N, Meganathan K, Natarajan K, Sachinidis A, Dahl A, et al. Regulation of liver metabolism by the endosomal GTPase Rab5. Cell Reports. 11: 884-92. PMID 25937276 DOI: 10.1016/J.Celrep.2015.04.018 |
0.384 |
|
2014 |
Sharma K, D'Souza RC, Tyanova S, Schaab C, Wi?niewski JR, Cox J, Mann M. Ultradeep human phosphoproteome reveals a distinct regulatory nature of Tyr and Ser/Thr-based signaling. Cell Reports. 8: 1583-94. PMID 25159151 DOI: 10.1016/J.Celrep.2014.07.036 |
0.525 |
|
2014 |
D'Souza RC, Knittle AM, Nagaraj N, van Dinther M, Choudhary C, ten Dijke P, Mann M, Sharma K. Time-resolved dissection of early phosphoproteome and ensuing proteome changes in response to TGF-β. Science Signaling. 7: rs5. PMID 25056879 DOI: 10.1126/Scisignal.2004856 |
0.452 |
|
2014 |
Gupta M, Sajid A, Sharma K, Ghosh S, Arora G, Singh R, Nagaraja V, Tandon V, Singh Y. HupB, a nucleoid-associated protein of Mycobacterium tuberculosis, is modified by serine/threonine protein kinases in vivo. Journal of Bacteriology. 196: 2646-57. PMID 24816602 DOI: 10.1128/Jb.01625-14 |
0.373 |
|
2012 |
Sharma K, Vabulas RM, Macek B, Pinkert S, Cox J, Mann M, Hartl FU. Quantitative proteomics reveals that Hsp90 inhibition preferentially targets kinases and the DNA damage response. Molecular & Cellular Proteomics : McP. 11: M111.014654. PMID 22167270 DOI: 10.1074/Mcp.M111.014654 |
0.567 |
|
2012 |
D'Souza RCJ, Sharma K, Korhonen AMM, Nagaraj N, Choudhary C, Dijke Pt, Mann M. Studying TGF-beta Signaling Using a High Resolution, Quantitative Mass Spectrometric Approach European Journal of Cancer. 48. DOI: 10.1016/S0959-8049(12)71302-3 |
0.407 |
|
2011 |
Monetti M, Nagaraj N, Sharma K, Mann M. Large-scale phosphosite quantification in tissues by a spike-in SILAC method. Nature Methods. 8: 655-8. PMID 21743459 DOI: 10.1038/Nmeth.1647 |
0.417 |
|
2010 |
Sharma K, Kumar C, Kéri G, Breitkopf SB, Oppermann FS, Daub H. Quantitative analysis of kinase-proximal signaling in lipopolysaccharide-induced innate immune response. Journal of Proteome Research. 9: 2539-49. PMID 20222745 DOI: 10.1021/Pr901192P |
0.37 |
|
2009 |
Sharma K, Weber C, Bairlein M, Greff Z, Kéri G, Cox J, Olsen JV, Daub H. Proteomics strategy for quantitative protein interaction profiling in cell extracts. Nature Methods. 6: 741-4. PMID 19749761 DOI: 10.1038/Nmeth.1373 |
0.355 |
|
2007 |
Narayan A, Sachdeva P, Sharma K, Saini AK, Tyagi AK, Singh Y. Serine threonine protein kinases of mycobacterial genus: phylogeny to function. Physiological Genomics. 29: 66-75. PMID 17148687 DOI: 10.1152/Physiolgenomics.00221.2006 |
0.372 |
|
2006 |
Sharma K, Gupta M, Krupa A, Srinivasan N, Singh Y. EmbR, a regulatory protein with ATPase activity, is a substrate of multiple serine/threonine kinases and phosphatase in Mycobacterium tuberculosis. The Febs Journal. 273: 2711-21. PMID 16817899 DOI: 10.1111/J.1742-4658.2006.05289.X |
0.417 |
|
2006 |
Sharma K, Gupta M, Pathak M, Gupta N, Koul A, Sarangi S, Baweja R, Singh Y. Transcriptional control of the mycobacterial embCAB operon by PknH through a regulatory protein, EmbR, in vivo. Journal of Bacteriology. 188: 2936-44. PMID 16585755 DOI: 10.1128/Jb.188.8.2936-2944.2006 |
0.368 |
|
2005 |
Chandra H, Gupta PK, Sharma K, Mattoo AR, Garg SK, Gade WN, Sirdeshmukh R, Maithal K, Singh Y. Proteome analysis of mouse macrophages treated with anthrax lethal toxin. Biochimica Et Biophysica Acta. 1747: 151-9. PMID 15698949 DOI: 10.1016/J.Bbapap.2004.10.012 |
0.381 |
|
2004 |
Chopra P, Koduri H, Singh R, Koul A, Ghildiyal M, Sharma K, Tyagi AK, Singh Y. Nucleoside diphosphate kinase of Mycobacterium tuberculosis acts as GTPase-activating protein for Rho-GTPases. Febs Letters. 571: 212-6. PMID 15280044 DOI: 10.1016/J.Febslet.2004.06.073 |
0.36 |
|
2004 |
Sharma K, Chopra P, Singh Y. Recent advances towards identification of new drug targets for Mycobacterium tuberculosis. Expert Opinion On Therapeutic Targets. 8: 79-93. PMID 15102551 DOI: 10.1517/14728222.8.2.79 |
0.304 |
|
2004 |
Sharma K, Chandra H, Gupta PK, Pathak M, Narayan A, Meena LS, D'Souza RC, Chopra P, Ramachandran S, Singh Y. PknH, a transmembrane Hank's type serine/threonine kinase from Mycobacterium tuberculosis is differentially expressed under stress conditions. Fems Microbiology Letters. 233: 107-13. PMID 15043876 DOI: 10.1016/J.Femsle.2004.01.045 |
0.387 |
|
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