| Year |
Citation |
Score |
| 2022 |
Atherton P, Konstantinou R, Neo SP, Wang E, Balloi E, Ptushkina M, Bennett H, Clark K, Gunaratne J, Critchley D, Barsukov I, Manser E, Ballestrem C. Tensin3 interaction with talin drives the formation of fibronectin-associated fibrillar adhesions. The Journal of Cell Biology. 221. PMID 36074065 DOI: 10.1083/jcb.202107022 |
0.323 |
|
| 2019 |
Atherton P, Lausecker F, Carisey A, Gilmore A, Critchley D, Barsukov I, Ballestrem C. Relief of talin autoinhibition triggers a force-independent association with vinculin Journal of Cell Biology. 219. DOI: 10.1083/Jcb.201903134 |
0.352 |
|
| 2017 |
Mathew S, Palamuttam RJ, Mernaugh G, Ramalingam H, Lu Z, Zhang MZ, Ishibe S, Critchley DR, Fässler R, Pozzi A, Sanders CR, Carroll TJ, Zent R. Talin regulates integrin β1 dependent and independent cell functions in ureteric bud development. Development (Cambridge, England). PMID 28993400 DOI: 10.1242/Dev.149914 |
0.418 |
|
| 2017 |
Manso AM, Okada H, Sakamoto FM, Moreno E, Monkley SJ, Li R, Critchley DR, Ross RS. Loss of mouse cardiomyocyte talin-1 and talin-2 leads to β-1 integrin reduction, costameric instability, and dilated cardiomyopathy. Proceedings of the National Academy of Sciences of the United States of America. PMID 28698364 DOI: 10.1073/Pnas.1701416114 |
0.304 |
|
| 2016 |
Zacharchenko T, Qian X, Goult BT, Jethwa D, Almeida TB, Ballestrem C, Critchley DR, Lowy DR, Barsukov IL. LD Motif Recognition by Talin: Structure of the Talin-DLC1 Complex. Structure (London, England : 1993). PMID 27265849 DOI: 10.1016/j.str.2016.04.016 |
0.353 |
|
| 2015 |
Atherton P, Stutchbury B, Wang DY, Jethwa D, Tsang R, Meiler-Rodriguez E, Wang P, Bate N, Zent R, Barsukov IL, Goult BT, Critchley DR, Ballestrem C. Vinculin controls talin engagement with the actomyosin machinery. Nature Communications. 6: 10038. PMID 26634421 DOI: 10.1038/Ncomms10038 |
0.508 |
|
| 2015 |
Liu J, Wang Y, Goh WI, Goh H, Baird MA, Ruehland S, Teo S, Bate N, Critchley DR, Davidson MW, Kanchanawong P. Talin determines the nanoscale architecture of focal adhesions. Proceedings of the National Academy of Sciences of the United States of America. 112: E4864-73. PMID 26283369 DOI: 10.1073/Pnas.1512025112 |
0.341 |
|
| 2015 |
Rainero E, Howe JD, Caswell PT, Jamieson NB, Anderson K, Critchley DR, Machesky L, Norman JC. Ligand-Occupied Integrin Internalization Links Nutrient Signaling to Invasive Migration. Cell Reports. PMID 25600874 DOI: 10.1016/J.Celrep.2014.12.037 |
0.36 |
|
| 2014 |
Tian X, Kim JJ, Monkley SM, Gotoh N, Nandez R, Soda K, Inoue K, Balkin DM, Hassan H, Son SH, Lee Y, Moeckel G, Calderwood DA, Holzman LB, Critchley DR, et al. Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance. The Journal of Clinical Investigation. 124: 1098-113. PMID 24531545 DOI: 10.1172/Jci69778 |
0.341 |
|
| 2013 |
Calderwood DA, Campbell ID, Critchley DR. Talins and kindlins: Partners in integrin-mediated adhesion Nature Reviews Molecular Cell Biology. 14: 503-517. PMID 23860236 DOI: 10.1038/Nrm3624 |
0.44 |
|
| 2013 |
Goult BT, Xu XP, Gingras AR, Swift M, Patel B, Bate N, Kopp PM, Barsukov IL, Critchley DR, Volkmann N, Hanein D. Structural studies on full-length talin1 reveal a compact auto-inhibited dimer: Implications for talin activation Journal of Structural Biology. 184: 21-32. PMID 23726984 DOI: 10.1016/J.Jsb.2013.05.014 |
0.459 |
|
| 2013 |
Goult BT, Zacharchenko T, Bate N, Tsang R, Hey F, Gingras AR, Elliott PR, Roberts GC, Ballestrem C, Critchley DR, Barsukov IL. RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover. The Journal of Biological Chemistry. 288: 8238-49. PMID 23389036 DOI: 10.1074/Jbc.M112.438119 |
0.503 |
|
| 2012 |
Bate N, Gingras AR, Bachir A, Horwitz R, Ye F, Patel B, Goult BT, Critchley DR. Talin contains a C-terminal calpain2 cleavage site important in focal adhesion dynamics Plos One. 7. PMID 22496808 DOI: 10.1371/Journal.Pone.0034461 |
0.437 |
|
| 2012 |
Lefort CT, Rossaint J, Moser M, Petrich BG, Zarbock A, Monkley SJ, Critchley DR, Ginsberg MH, Fässler R, Ley K. Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation. Blood. 119: 4275-82. PMID 22431571 DOI: 10.1182/Blood-2011-08-373118 |
0.381 |
|
| 2012 |
Banno A, Goult BT, Lee H, Bate N, Critchley DR, Ginsberg MH. Subcellular localization of talin is regulated by inter-domain interactions. The Journal of Biological Chemistry. 287: 13799-812. PMID 22351767 DOI: 10.1074/Jbc.M112.341214 |
0.398 |
|
| 2012 |
Praekelt U, Kopp PM, Rehm K, Linder S, Bate N, Patel B, Debrand E, Manso AM, Ross RS, Conti F, Zhang MZ, Harris RC, Zent R, Critchley DR, Monkley SJ. New isoform-specific monoclonal antibodies reveal different sub-cellular localisations for talin1 and talin2. European Journal of Cell Biology. 91: 180-91. PMID 22306379 DOI: 10.1016/J.Ejcb.2011.12.003 |
0.353 |
|
| 2012 |
Bouaouina M, Goult BT, Huet-Calderwood C, Bate N, Brahme NN, Barsukov IL, Critchley DR, Calderwood DA. A conserved lipid-binding loop in the kindlin FERM F1 domain is required for kindlin-mediated αIIbβ3 integrin coactivation. The Journal of Biological Chemistry. 287: 6979-90. PMID 22235127 DOI: 10.1074/Jbc.M111.330845 |
0.517 |
|
| 2012 |
Lefort CT, Rossaint J, Moser M, Petrich BG, Zarbock A, Monkley SJ, Critchley DR, Ginsberg MH, Fässler R, Ley K. Distinct Roles for Talin-1 and Kindlin-3 in Regulating LFA-1 Conformation during Neutrophil Rolling and Arrest Biophysical Journal. 102: 347a. DOI: 10.1016/J.Bpj.2011.11.1900 |
0.439 |
|
| 2011 |
Truttmann MC, Misselwitz B, Huser S, Hardt WD, Critchley DR, Dehio C. Bartonella henselae engages inside-out and outside-in signaling by integrin β1 and talin1 during invasome-mediated bacterial uptake. Journal of Cell Science. 124: 3591-602. PMID 22045736 DOI: 10.1242/Jcs.084459 |
0.357 |
|
| 2011 |
Liu J, He X, Qi Y, Tian X, Monkley SJ, Critchley DR, Corbett SA, Lowry SF, Graham AM, Li S. Talin1 regulates integrin turnover to promote embryonic epithelial morphogenesis Molecular and Cellular Biology. 31: 3366-3377. PMID 21670148 DOI: 10.1128/Mcb.01403-10 |
0.403 |
|
| 2011 |
Haling JR, Monkley SJ, Critchley DR, Petrich BG. Talin-dependent integrin activation is required for fibrin clot retraction by platelets. Blood. 117: 1719-22. PMID 20971947 DOI: 10.1182/Blood-2010-09-305433 |
0.355 |
|
| 2010 |
Anthis NJ, Wegener KL, Critchley DR, Campbell ID. Structural diversity in integrin/talin interactions Structure. 18: 1654-1666. PMID 21134644 DOI: 10.1016/J.Str.2010.09.018 |
0.376 |
|
| 2010 |
Elliott PR, Goult BT, Kopp PM, Bate N, Grossmann JG, Roberts GC, Critchley DR, Barsukov IL. The Structure of the talin head reveals a novel extended conformation of the FERM domain. Structure (London, England : 1993). 18: 1289-99. PMID 20947018 DOI: 10.1016/J.Str.2010.07.011 |
0.436 |
|
| 2010 |
Lim J, Dupuy AG, Critchley DR, Caron E. Rap1 controls activation of the α(M)β(2) integrin in a talin-dependent manner. Journal of Cellular Biochemistry. 111: 999-1009. PMID 20665668 DOI: 10.1002/Jcb.22788 |
0.343 |
|
| 2010 |
Gingras AR, Bate N, Goult BT, Patel B, Kopp PM, Emsley J, Barsukov IL, Roberts GC, Critchley DR. Central region of talin has a unique fold that binds vinculin and actin. The Journal of Biological Chemistry. 285: 29577-87. PMID 20610383 DOI: 10.1074/Jbc.M109.095455 |
0.508 |
|
| 2010 |
Kopp PM, Bate N, Hansen TM, Brindle NPJ, Praekelt U, Debrand E, Coleman S, Mazzeo D, Goult BT, Gingras AR, Pritchard CA, Critchley DR, Monkley SJ. Studies on the morphology and spreading of human endothelial cells define key inter- and intramolecular interactions for talin1 European Journal of Cell Biology. 89: 661-673. PMID 20605055 DOI: 10.1016/J.Ejcb.2010.05.003 |
0.528 |
|
| 2010 |
Goult BT, Gingras AR, Bate N, Barsukov IL, Critchley DR, Roberts GC. The domain structure of talin: residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site. Febs Letters. 584: 2237-41. PMID 20399778 DOI: 10.1016/J.Febslet.2010.04.028 |
0.513 |
|
| 2010 |
Goult BT, Bouaouina M, Elliott PR, Bate N, Patel B, Gingras AR, Grossmann JG, Roberts GC, Calderwood DA, Critchley DR, Barsukov IL. Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation. The Embo Journal. 29: 1069-80. PMID 20150896 DOI: 10.1038/Emboj.2010.4 |
0.398 |
|
| 2010 |
Clark K, Howe JD, Pullar CE, Green JA, Artym VV, Yamada KM, Critchley DR. Tensin 2 modulates cell contractility in 3D collagen gels through the RhoGAP DLC1. Journal of Cellular Biochemistry. 109: 808-17. PMID 20069572 DOI: 10.1002/Jcb.22460 |
0.4 |
|
| 2009 |
Roberts GCK, Critchley DR. Structural and biophysical properties of the integrin-associated cytoskeletal protein talin. Biophysical Reviews. 1: 61-69. PMID 28509985 DOI: 10.1007/S12551-009-0009-4 |
0.545 |
|
| 2009 |
Goult BT, Bouaouina M, Harburger DS, Bate N, Patel B, Anthis NJ, Campbell ID, Calderwood DA, Barsukov IL, Roberts GC, Critchley DR. The structure of the N-terminus of kindlin-1: a domain important for alphaiibbeta3 integrin activation. Journal of Molecular Biology. 394: 944-56. PMID 19804783 DOI: 10.1016/J.Jmb.2009.09.061 |
0.403 |
|
| 2009 |
Anthis NJ, Wegener KL, Ye F, Kim C, Goult BT, Lowe ED, Vakonakis I, Bate N, Critchley DR, Ginsberg MH, Campbell ID. The structure of an integrin/talin complex reveals the basis of inside-out signal transduction Embo Journal. 28: 3623-3632. PMID 19798053 DOI: 10.1038/Emboj.2009.287 |
0.429 |
|
| 2009 |
Conti FJ, Monkley SJ, Wood MR, Critchley DR, Müller U. Talin 1 and 2 are required for myoblast fusion, sarcomere assembly and the maintenance of myotendinous junctions. Development (Cambridge, England). 136: 3597-606. PMID 19793892 DOI: 10.1242/Dev.035857 |
0.327 |
|
| 2009 |
Critchley DR. Biochemical and structural properties of the integrin-associated cytoskeletal protein talin. Annual Review of Biophysics. 38: 235-54. PMID 19416068 DOI: 10.1146/Annurev.Biophys.050708.133744 |
0.447 |
|
| 2009 |
Critchley DR. Smurf1 zaps the talin head. Nature Cell Biology. 11: 538-40. PMID 19404335 DOI: 10.1038/Ncb0509-538 |
0.312 |
|
| 2009 |
Goult BT, Bate N, Anthis NJ, Wegener KL, Gingras AR, Patel B, Barsukov IL, Campbell ID, Roberts GC, Critchley DR. The structure of an interdomain complex that regulates talin activity. The Journal of Biological Chemistry. 284: 15097-106. PMID 19297334 DOI: 10.1074/Jbc.M900078200 |
0.503 |
|
| 2009 |
Debrand E, El Jai Y, Spence L, Bate N, Praekelt U, Pritchard CA, Monkley SJ, Critchley DR. Talin 2 is a large and complex gene encoding multiple transcripts and protein isoforms. The Febs Journal. 276: 1610-28. PMID 19220457 DOI: 10.1111/J.1742-4658.2009.06893.X |
0.355 |
|
| 2009 |
Gingras AR, Ziegler WH, Bobkov AA, Joyce MG, Fasci D, Himmel M, Rothemund S, Ritter A, Grossmann JG, Patel B, Bate N, Goult BT, Emsley J, Barsukov IL, Roberts GC, ... ... Critchley DR, et al. Structural determinants of integrin binding to the talin rod. The Journal of Biological Chemistry. 284: 8866-76. PMID 19176533 DOI: 10.1074/Jbc.M805937200 |
0.518 |
|
| 2009 |
Mace EM, Monkley SJ, Critchley DR, Takei F. A dual role for talin in NK cell cytotoxicity: activation of LFA-1-mediated cell adhesion and polarization of NK cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 948-56. PMID 19124737 DOI: 10.4049/Jimmunol.182.2.948 |
0.34 |
|
| 2008 |
Goult BT, Gingras AR, Bate N, Roberts GC, Critchley DR, Barsukov IL. NMR assignment of the C-terminal actin-binding domain of talin. Biomolecular Nmr Assignments. 2: 17-9. PMID 19636914 DOI: 10.1007/S12104-007-9073-5 |
0.471 |
|
| 2008 |
Zhang X, Jiang G, Cai Y, Monkley SJ, Critchley DR, Sheetz MP. Talin depletion reveals independence of initial cell spreading from integrin activation and traction. Nature Cell Biology. 10: 1062-8. PMID 19160486 DOI: 10.1038/Ncb1765 |
0.444 |
|
| 2008 |
Holt MR, Calle Y, Sutton DH, Critchley DR, Jones GE, Dunn GA. Quantifying cell-matrix adhesion dynamics in living cells using interference reflection microscopy. Journal of Microscopy. 232: 73-81. PMID 19017203 DOI: 10.1111/J.1365-2818.2008.02069.X |
0.327 |
|
| 2008 |
Srivastava J, Barreiro G, Groscurth S, Gingras AR, Goult BT, Critchley DR, Kelly MJ, Jacobson MP, Barber DL. Structural model and functional significance of pH-dependent talin-actin binding for focal adhesion remodeling. Proceedings of the National Academy of Sciences of the United States of America. 105: 14436-41. PMID 18780792 DOI: 10.1073/Pnas.0805163105 |
0.421 |
|
| 2008 |
Wegener KL, Basran J, Bagshaw CR, Campbell ID, Roberts GC, Critchley DR, Barsukov IL. Structural basis for the interaction between the cytoplasmic domain of the hyaluronate receptor layilin and the talin F3 subdomain. Journal of Molecular Biology. 382: 112-26. PMID 18638481 DOI: 10.1016/J.Jmb.2008.06.087 |
0.691 |
|
| 2008 |
Lämmermann T, Bader BL, Monkley SJ, Worbs T, Wedlich-Söldner R, Hirsch K, Keller M, Förster R, Critchley DR, Fässler R, Sixt M. Rapid leukocyte migration by integrin-independent flowing and squeezing. Nature. 453: 51-5. PMID 18451854 DOI: 10.1038/Nature06887 |
0.348 |
|
| 2008 |
Critchley DR, Gingras AR. Talin at a glance Journal of Cell Science. 121: 1345-1347. PMID 18434644 DOI: 10.1242/Jcs.018085 |
0.329 |
|
| 2008 |
Ziegler WH, Gingras AR, Critchley DR, Emsley J. Integrin connections to the cytoskeleton through talin and vinculin Biochemical Society Transactions. 36: 235-239. PMID 18363566 DOI: 10.1042/Bst0360235 |
0.539 |
|
| 2008 |
Sun N, Critchley DR, Paulin D, Li Z, Robson RM. Identification of a repeated domain within mammalian alpha-synemin that interacts directly with talin. Experimental Cell Research. 314: 1839-49. PMID 18342854 DOI: 10.1016/J.Yexcr.2008.01.034 |
0.422 |
|
| 2008 |
Wang Y, Litvinov RI, Chen X, Bach TL, Lian L, Petrich BG, Monkley SJ, Kanaho Y, Critchley DR, Sasaki T, Birnbaum MJ, Weisel JW, Hartwig J, Abrams CS. Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes. The Journal of Clinical Investigation. 118: 812-9. PMID 18188447 DOI: 10.1172/Jci34239 |
0.367 |
|
| 2008 |
Gingras AR, Bate N, Goult BT, Hazelwood L, Canestrelli I, Grossmann JG, Liu H, Putz NS, Roberts GC, Volkmann N, Hanein D, Barsukov IL, Critchley DR. The structure of the C-terminal actin-binding domain of talin. The Embo Journal. 27: 458-69. PMID 18157087 DOI: 10.1038/Sj.Emboj.7601965 |
0.526 |
|
| 2008 |
Sun N, Critchley DR, Paulin D, Li Z, Robson RM. Human alpha-synemin interacts directly with vinculin and metavinculin. The Biochemical Journal. 409: 657-67. PMID 18028034 DOI: 10.1042/Bj20071188 |
0.405 |
|
| 2008 |
Goult B, Gingras A, Bate N, Critchley D, Barsukov I. NMR structure of the talin C-terminal actin binding site Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Jsw/Pdb |
0.441 |
|
| 2008 |
Goult B, Gingras A, Critchley D, Barsukov I. NMR Structure of the VBS3 domain (residues 1815-1973) of Talin Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr15625 |
0.331 |
|
| 2007 |
Moes M, Rodius S, Coleman SJ, Monkley SJ, Goormaghtigh E, Tremuth L, Kox C, van der Holst PP, Critchley DR, Kieffer N. The integrin binding site 2 (IBS2) in the talin rod domain is essential for linking integrin beta subunits to the cytoskeleton. The Journal of Biological Chemistry. 282: 17280-8. PMID 17430904 DOI: 10.1074/Jbc.M611846200 |
0.527 |
|
| 2007 |
Lim J, Wiedemann A, Tzircotis G, Monkley SJ, Critchley DR, Caron E. An essential role for talin during alpha(M)beta(2)-mediated phagocytosis. Molecular Biology of the Cell. 18: 976-85. PMID 17202407 DOI: 10.1091/Mbc.E06-09-0813 |
0.352 |
|
| 2007 |
Nieswandt B, Moser M, Pleines I, Varga-Szabo D, Monkley S, Critchley D, Fässler R. Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo The Journal of Cell Biology. 179: i19-i19. DOI: 10.1084/Jem.20071827 |
0.317 |
|
| 2006 |
Ziegler WH, Liddington RC, Critchley DR. The structure and regulation of vinculin Trends in Cell Biology. 16: 453-460. PMID 16893648 DOI: 10.1016/J.Tcb.2006.07.004 |
0.492 |
|
| 2006 |
Saunders RM, Holt MR, Jennings L, Sutton DH, Barsukov IL, Bobkov A, Liddington RC, Adamson EA, Dunn GA, Critchley DR. Role of vinculin in regulating focal adhesion turnover. European Journal of Cell Biology. 85: 487-500. PMID 16584805 DOI: 10.1016/J.Ejcb.2006.01.014 |
0.475 |
|
| 2006 |
Gingras AR, Vogel KP, Steinhoff HJ, Ziegler WH, Patel B, Emsley J, Critchley DR, Roberts GC, Barsukov IL. Structural and dynamic characterization of a vinculin binding site in the talin rod. Biochemistry. 45: 1805-17. PMID 16460027 DOI: 10.1021/Bi052136L |
0.506 |
|
| 2006 |
Patel B, Gingras AR, Bobkov AA, Fujimoto LM, Zhang M, Liddington RC, Mazzeo D, Emsley J, Roberts GC, Barsukov IL, Critchley DR. The activity of the vinculin binding sites in talin is influenced by the stability of the helical bundles that make up the talin rod. The Journal of Biological Chemistry. 281: 7458-67. PMID 16407302 DOI: 10.1074/Jbc.M508058200 |
0.48 |
|
| 2006 |
Critchley DR. Genetic, biochemical and structural approaches to talin function. Biochemical Society Transactions. 33: 1308-12. PMID 16246105 DOI: 10.1042/Bst0331308 |
0.328 |
|
| 2005 |
Gingras AR, Ziegler WH, Frank R, Barsukov IL, Roberts GC, Critchley DR, Emsley J. Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod. The Journal of Biological Chemistry. 280: 37217-24. PMID 16135522 DOI: 10.1074/Jbc.M508060200 |
0.51 |
|
| 2005 |
Woods AJ, Kantidakis T, Sabe H, Critchley DR, Norman JC. Interaction of paxillin with poly(A)-binding protein 1 and its role in focal adhesion turnover and cell migration. Molecular and Cellular Biology. 25: 3763-73. PMID 15831480 DOI: 10.1128/Mcb.25.9.3763-3773.2005 |
0.452 |
|
| 2005 |
Fillingham I, Gingras AR, Papagrigoriou E, Patel B, Emsley J, Critchley DR, Roberts GC, Barsukov IL. A vinculin binding domain from the talin rod unfolds to form a complex with the vinculin head. Structure (London, England : 1993). 13: 65-74. PMID 15642262 DOI: 10.1016/J.Str.2004.11.006 |
0.517 |
|
| 2005 |
de Pereda JM, Wegener KL, Santelli E, Bate N, Ginsberg MH, Critchley DR, Campbell ID, Liddington RC. Structural basis for phosphatidylinositol phosphate kinase type Igamma binding to talin at focal adhesions. The Journal of Biological Chemistry. 280: 8381-6. PMID 15623515 DOI: 10.1074/Jbc.M413180200 |
0.473 |
|
| 2005 |
Critchley DR. Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion. Biochemical Society Transactions. 32: 831-6. PMID 15494027 DOI: 10.1042/Bst0320831 |
0.377 |
|
| 2004 |
Lee HS, Bellin RM, Walker DL, Patel B, Powers P, Liu H, Garcia-Alvarez B, de Pereda JM, Liddington RC, Volkmann N, Hanein D, Critchley DR, Robson RM. Characterization of an actin-binding site within the talin FERM domain. Journal of Molecular Biology. 343: 771-84. PMID 15465061 DOI: 10.1016/J.Jmb.2004.08.069 |
0.502 |
|
| 2004 |
Franco SJ, Rodgers MA, Perrin BJ, Han J, Bennin DA, Critchley DR, Huttenlocher A. Calpain-mediated proteolysis of talin regulates adhesion dynamics. Nature Cell Biology. 6: 977-83. PMID 15448700 DOI: 10.1038/Ncb1175 |
0.345 |
|
| 2004 |
Papagrigoriou E, Gingras AR, Barsukov IL, Bate N, Fillingham IJ, Patel B, Frank R, Ziegler WH, Roberts GC, Critchley DR, Emsley J. Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle. The Embo Journal. 23: 2942-51. PMID 15272303 DOI: 10.1038/Sj.Emboj.7600285 |
0.492 |
|
| 2004 |
Bakolitsa C, Cohen DM, Bankston LA, Bobkov AA, Cadwell GW, Jennings L, Critchley DR, Craig SW, Liddington RC. Structural basis for vinculin activation at sites of cell adhesion. Nature. 430: 583-6. PMID 15195105 DOI: 10.1038/Nature02610 |
0.512 |
|
| 2004 |
Papagrigoriou E, Gingras A, Critchley DR, Emsley J. Activation of a vinculin binding site (VBS) in the talin rod involves rearrangement of a five-helix bundle Acta Crystallographica Section A. 60: 25-25. DOI: 10.1107/S0108767304099519 |
0.433 |
|
| 2003 |
Giannone G, Jiang G, Sutton DH, Critchley DR, Sheetz MP. Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation. The Journal of Cell Biology. 163: 409-19. PMID 14581461 DOI: 10.1083/Jcb.200302001 |
0.336 |
|
| 2003 |
Jiang G, Giannone G, Critchley DR, Fukumoto E, Sheetz MP. Two-piconewton slip bond between fibronectin and the cytoskeleton depends on talin. Nature. 424: 334-7. PMID 12867986 DOI: 10.1038/Nature01805 |
0.406 |
|
| 2003 |
Barsukov IL, Prescot A, Bate N, Patel B, Floyd DN, Bhanji N, Bagshaw CR, Letinic K, Di Paolo G, De Camilli P, Roberts GC, Critchley DR. Phosphatidylinositol phosphate kinase type 1gamma and beta1-integrin cytoplasmic domain bind to the same region in the talin FERM domain. The Journal of Biological Chemistry. 278: 31202-9. PMID 12782621 DOI: 10.1074/Jbc.M303850200 |
0.672 |
|
| 2003 |
Fraley TS, Tran TC, Corgan AM, Nash CA, Hao J, Critchley DR, Greenwood JA. Phosphoinositide binding inhibits α-actinin bundling activity Journal of Biological Chemistry. 278: 24039-24045. PMID 12716899 DOI: 10.1074/Jbc.M213288200 |
0.397 |
|
| 2003 |
García-Alvarez B, de Pereda JM, Calderwood DA, Ulmer TS, Critchley D, Campbell ID, Ginsberg MH, Liddington RC. Structural determinants of integrin recognition by talin. Molecular Cell. 11: 49-58. PMID 12535520 DOI: 10.1016/S1097-2765(02)00823-7 |
0.47 |
|
| 2002 |
Bass MD, Patel B, Barsukov IG, Fillingham IJ, Mason R, Smith BJ, Bagshaw CR, Critchley DR. Further characterization of the interaction between the cytoskeletal proteins talin and vinculin. The Biochemical Journal. 362: 761-8. PMID 11879206 DOI: 10.1042/Bj3620761 |
0.797 |
|
| 2002 |
Woods AJ, Roberts MS, Choudhary J, Barry ST, Mazaki Y, Sabe H, Morley SJ, Critchley DR, Norman JC. Paxillin associates with poly(A)-binding protein 1 at the dense endoplasmic reticulum and the leading edge of migrating cells. The Journal of Biological Chemistry. 277: 6428-37. PMID 11704675 DOI: 10.1074/jbc.M109446200 |
0.338 |
|
| 2001 |
Bellin RM, Huiatt TW, Critchley DR, Robson RM. Synemin may function to directly link muscle cell intermediate filaments to both myofibrillar Z-lines and costameres. The Journal of Biological Chemistry. 276: 32330-7. PMID 11418616 DOI: 10.1074/Jbc.M104005200 |
0.432 |
|
| 2000 |
Critchley DR. Focal adhesions - the cytoskeletal connection. Current Opinion in Cell Biology. 12: 133-9. PMID 10679361 DOI: 10.1016/S0955-0674(99)00067-8 |
0.427 |
|
| 2000 |
Bakolitsa C, Pereda JMD, Bagshaw CR, Critchley DR, Liddington RC. Crystal Structure of the Vinculin Tail and a Pathway for Activation Cell. 99: 603. DOI: 10.2210/Pdb1Qkr/Pdb |
0.54 |
|
| 1999 |
Bakolitsa C, de Pereda JM, Bagshaw CR, Critchley DR, Liddington RC. Crystal structure of the vinculin tail suggests a pathway for activation. Cell. 99: 603-13. PMID 10612396 DOI: 10.1016/S0092-8674(00)81549-4 |
0.684 |
|
| 1999 |
Cattelino A, Albertinazzi C, Bossi M, Critchley DR, de Curtis I. A cell-free system to study regulation of focal adhesions and of the connected actin cytoskeleton. Molecular Biology of the Cell. 10: 373-91. PMID 9950683 DOI: 10.1091/Mbc.10.2.373 |
0.366 |
|
| 1999 |
BASS MD, SMITH BJ, PRIGENT SA, CRITCHLEY DR. Talin contains three similar vinculin-binding sites predicted to form an amphipathic helix Biochemical Journal. 341: 257. DOI: 10.1042/Bj3410257 |
0.762 |
|
| 1999 |
BASS MD, SMITH BJ, PRIGENT SA, CRITCHLEY DR. Talin contains three similar vinculin-binding sites predicted to form an amphipathic helix Biochemical Journal. 341: 257-263. DOI: 10.1042/BJ3410257 |
0.392 |
|
| 1998 |
Norman JC, Jones D, Barry ST, Holt MR, Cockcroft S, Critchley DR. ARF1 mediates paxillin recruitment to focal adhesions and potentiates Rho-stimulated stress fiber formation in intact and permeabilized Swiss 3T3 fibroblasts. The Journal of Cell Biology. 143: 1981-95. PMID 9864369 DOI: 10.1083/Jcb.143.7.1981 |
0.311 |
|
| 1998 |
Priddle H, Hemmings L, Monkley S, Woods A, Patel B, Sutton D, Dunn GA, Zicha D, Critchley DR. Disruption of the talin gene compromises focal adhesion assembly in undifferentiated but not differentiated embryonic stem cells. The Journal of Cell Biology. 142: 1121-33. PMID 9722622 DOI: 10.1083/Jcb.142.4.1121 |
0.375 |
|
| 1998 |
Holt MR, Critchley DR, Brindle NP. Molecules in focus The focal adhesion phosphoprotein, VASP The International Journal of Biochemistry & Cell Biology. 30: 307-311. DOI: 10.1016/S1357-2725(97)00101-5 |
0.455 |
|
| 1997 |
Jones JL, Royall JE, Critchley DR, Walker RA. Modulation of myoepithelial-associated alpha6beta4 integrin in a breast cancer cell line alters invasive potential. Experimental Cell Research. 235: 325-33. PMID 9299156 DOI: 10.1006/Excr.1997.3662 |
0.305 |
|
| 1997 |
Flood G, Rowe AJ, Critchley DR, Gratzer WB. Further analysis of the role of spectrin repeat motifs in alpha-actinin dimer formation. European Biophysics Journal : Ebj. 25: 431-5. PMID 9188165 DOI: 10.1007/S002490050057 |
0.41 |
|
| 1997 |
Barry ST, Flinn HM, Humphries MJ, Critchley DR, Ridley AJ. Requirement for Rho in integrin signalling. Cell Adhesion and Communication. 4: 387-98. PMID 9177901 DOI: 10.3109/15419069709004456 |
0.42 |
|
| 1997 |
Bolton SJ, Barry ST, Mosley H, Patel B, Jockusch BM, Wilkinson JM, Critchley DR. Monoclonal antibodies recognizing the N- and C-terminal regions of talin disrupt actin stress fibers when microinjected into human fibroblasts. Cell Motility and the Cytoskeleton. 36: 363-76. PMID 9096958 DOI: 10.1002/(Sici)1097-0169(1997)36:4<363::Aid-Cm6>3.0.Co;2-6 |
0.485 |
|
| 1996 |
Retta SF, Barry ST, Critchley DR, Defilippi P, Silengo L, Tarone G. Focal adhesion and stress fiber formation is regulated by tyrosine phosphatase activity. Experimental Cell Research. 229: 307-17. PMID 8986614 DOI: 10.1006/Excr.1996.0376 |
0.313 |
|
| 1996 |
Brindle NP, Holt MR, Davies JE, Price CJ, Critchley DR. The focal-adhesion vasodilator-stimulated phosphoprotein (VASP) binds to the proline-rich domain in vinculin. The Biochemical Journal. 753-7. PMID 8836115 DOI: 10.1042/Bj3180753 |
0.508 |
|
| 1996 |
Heiska L, Kantor C, Parr T, Critchley DR, Vilja P, Gahmberg CG, Carpén O. Binding of the cytoplasmic domain of intercellular adhesion molecule-2 (ICAM-2) to alpha-actinin. The Journal of Biological Chemistry. 271: 26214-9. PMID 8824270 DOI: 10.1074/Jbc.271.42.26214 |
0.404 |
|
| 1996 |
Moiseeva EP, Belkin AM, Spurr NK, Koteliansky VE, Critchley DR. A novel dystrophin/utrophin-associated protein is an enzymatically inactive member of the phosphoglucomutase superfamily. European Journal of Biochemistry. 235: 103-13. PMID 8631316 DOI: 10.1111/J.1432-1033.1996.00103.X |
0.337 |
|
| 1996 |
Weekes J, Barry ST, Critchley DR. Acidic phospholipids inhibit the intramolecular association between the N- and C-terminal regions of vinculin, exposing actin-binding and protein kinase C phosphorylation sites. The Biochemical Journal. 314: 827-32. PMID 8615776 DOI: 10.1042/Bj3140827 |
0.491 |
|
| 1995 |
Hemmings L, Barry ST, Critchley DR. Cell-matrix adhesion: structure and regulation. Biochemical Society Transactions. 23: 619-26. PMID 8566429 DOI: 10.1042/Bst0230619 |
0.435 |
|
| 1995 |
Winder SJ, Hemmings L, Bolton SJ, Maciver SK, Tinsley JM, Davies KE, Critchley DR, Kendrick-Jones J. Calmodulin regulation of utrophin actin binding. Biochemical Society Transactions. 23: 397S. PMID 8566285 DOI: 10.1042/Bst023397S |
0.452 |
|
| 1994 |
Kuhlman PA, Ellis J, Critchley DR, Bagshaw CR. The kinetics of the interaction between the actin-binding domain of alpha-actinin and F-actin. Febs Letters. 339: 297-301. PMID 8112470 DOI: 10.1016/0014-5793(94)80434-6 |
0.772 |
|
| 1994 |
McGregor A, Blanchard AD, Rowe AJ, Critchley DR. Identification of the vinculin-binding site in the cytoskeletal protein alpha-actinin. The Biochemical Journal. 301: 225-33. PMID 8037676 DOI: 10.1042/Bj3010225 |
0.454 |
|
| 1994 |
Gilmore AP, Parr T, Patel B, Gratzer WB, Critchley DR. Analysis of the phasing of four spectrin-like repeats in alpha-actinin. European Journal of Biochemistry. 225: 235-42. PMID 7925443 DOI: 10.1111/J.1432-1033.1994.00235.X |
0.399 |
|
| 1994 |
Orlandi PA, Critchley DR, Fishman PH. The Heat-Labile Enterotoxin of Escherichia coli Binds to Polylactosaminoglycan-Containing Receptors in CaCo-2 Human Intestinal Epithelial Cells Biochemistry. 33: 12886-12895. DOI: 10.1021/Bi00209A021 |
0.349 |
|
| 1993 |
Gilmore AP, Wood C, Ohanian V, Jackson P, Patel B, Rees DJ, Hynes RO, Critchley DR. The cytoskeletal protein talin contains at least two distinct vinculin binding domains. The Journal of Cell Biology. 122: 337-47. PMID 8320257 DOI: 10.1083/Jcb.122.2.337 |
0.477 |
|
| 1993 |
Parr T, Waites GT, Patel B, Millake DB, Critchley DR. A chick skeletal-muscle alpha-actinin gene gives rise to two alternatively spliced isoforms which differ in the EF-hand Ca(2+)-binding domain. European Journal of Biochemistry. 210: 801-9. PMID 1483465 DOI: 10.1111/J.1432-1033.1992.Tb17483.X |
0.32 |
|
| 1992 |
Hemmings L, Kuhlman PA, Critchley DR. Analysis of the actin-binding domain of alpha-actinin by mutagenesis and demonstration that dystrophin contains a functionally homologous domain. The Journal of Cell Biology. 116: 1369-80. PMID 1541634 DOI: 10.1083/Jcb.116.6.1369 |
0.806 |
|
| 1992 |
Koteliansky VE, Ogryzko EP, Zhidkova NI, Weller PA, Critchley DR, Vancompernolle K, Vandekerckhove J, Strasser P, Way M, Gimona M. An additional exon in the human vinculin gene specifically encodes meta-vinculin-specific difference peptide. Cross-species comparison reveals variable and conserved motifs in the meta-vinculin insert. European Journal of Biochemistry / Febs. 204: 767-72. PMID 1339348 DOI: 10.1111/J.1432-1033.1992.Tb16692.X |
0.322 |
|
| 1992 |
Kuhlman PA, Hemmings L, Critchley DR. The identification and characterisation of an actin-binding site in α-actinin by mutagenesis Febs Letters. 304: 201-206. DOI: 10.1016/0014-5793(92)80619-R |
0.8 |
|
| 1991 |
Davison MD, Baron MD, Critchley DR, Wootton JC. Structural analysis of homologous repeated domains in alpha-actinin and spectrin. International Journal of Biological Macromolecules. 11: 81-90. PMID 2489070 DOI: 10.1016/0141-8130(89)90047-0 |
0.379 |
|
| 1990 |
Jones P, Jackson P, Price GJ, Patel B, Ohanion V, Lear AL, Critchley DR. Identification of a talin binding site in the cytoskeletal protein vinculin. The Journal of Cell Biology. 109: 2917-27. PMID 2512301 DOI: 10.1083/Jcb.109.6.2917 |
0.512 |
|
| 1989 |
Price GJ, Jones P, Davison MD, Patel B, Bendori R, Geiger B, Critchley DR. Primary sequence and domain structure of chicken vinculin. The Biochemical Journal. 259: 453-61. PMID 2497736 DOI: 10.1042/Bj2590453 |
0.426 |
|
| 1988 |
Davison MD, Critchley DR. alpha-Actinins and the DMD protein contain spectrin-like repeats. Cell. 52: 159-60. PMID 3342446 DOI: 10.1016/0092-8674(88)90503-X |
0.327 |
|
| 1987 |
Pierce EJ, Davison MD, Parton RG, Habig WH, Critchley DR. Characterization of tetanus toxin binding to rat brain membranes. Evidence for a high-affinity proteinase-sensitive receptor. The Biochemical Journal. 236: 845-52. PMID 3539106 DOI: 10.1042/Bj2360845 |
0.395 |
|
| 1987 |
KELLIE S, WIGGLESWORTH NM, PATEL B, HOLME TC, CRITCHLEY DR, WYKE JA. Membrane and cytoskeletal changes in cells after transformation by Rous Sarcoma virus Biochemical Society Transactions. 15: 791-794. DOI: 10.1042/Bst0150791 |
0.34 |
|
| 1986 |
Kellie S, Patel B, Wigglesworth NM, Critchley DR, Wyke JA. The use of Rous sarcoma virus transformation mutants with differing tyrosine kinase activities to study the relationships between vinculin phosphorylation, pp60v-src location and adhesion plaque integrity. Experimental Cell Research. 165: 216-28. PMID 3011478 DOI: 10.1016/0014-4827(86)90546-X |
0.321 |
|
| 1986 |
Griffiths SL, Perkins RM, Streuli CH, Critchley DR. Variants of BALB/c 3T3 cells lacking complex gangliosides retain a fibronectin matrix and spread normally on fibronectin-coated substrates. The Journal of Cell Biology. 102: 469-76. PMID 2935542 DOI: 10.1083/Jcb.102.2.469 |
0.312 |
|
| 1985 |
Critchley DR, Nelson PG, Habig WH, Fishman PH. Fate of tetanus toxin bound to the surface of primary neurons in culture: evidence for rapid internalization. The Journal of Cell Biology. 100: 1499-507. PMID 3988797 DOI: 10.1083/Jcb.100.5.1499 |
0.327 |
|
| 1985 |
Streuli CH, Griffiths SL, Critchley DR. Isolation of variants of BALB/c 3T3 cells defective in complex ganglioside biosynthesis. Experimental Cell Research. 156: 260-70. PMID 3965291 DOI: 10.1016/0014-4827(85)90280-0 |
0.3 |
|
| 1983 |
Yamada KM, Critchley DR, Fishman PH, Moss J. Exogenous gangliosides enhance the interaction of fibronectin with ganglioside-deficient cells. Experimental Cell Research. 143: 295-302. PMID 6832218 DOI: 10.1016/0014-4827(83)90054-X |
0.418 |
|
| 1983 |
Kellie S, Patel B, Pierce EJ, Critchley DR. Capping of cholera toxin-ganglioside GM1 complexes on mouse lymphocytes is accompanied by co-capping of alpha-actinin. The Journal of Cell Biology. 97: 447-54. PMID 6684122 DOI: 10.1083/Jcb.97.2.447 |
0.362 |
|
| 1982 |
Streuli CH, Patel B, Critchley DR. The cholera toxin receptor ganglioside GM remains associated with triton X-100 cytoskeletons of BALB/c-3T3 cells. Experimental Cell Research. 136: 247-54. PMID 7198048 DOI: 10.1016/0014-4827(81)90002-1 |
0.328 |
|
| 1982 |
Critchley DR, Streuli CH, Kellie S, Ansell S, Patel B. Characterization of the cholera toxin receptor on Balb/c 3T3 cells as a ganglioside similar to, or identical with, ganglioside GM1. No evidence for galactoproteins with receptor activity. The Biochemical Journal. 204: 209-19. PMID 7052064 DOI: 10.1042/Bj2040209 |
0.38 |
|
| 1982 |
Perkins RM, Kellie S, Patel B, Critchley DR. Gangliosides as receptors for fibronectin? Comparison of cell spreading on a ganglioside-specific ligand with that on fibronectin. Experimental Cell Research. 141: 231-43. PMID 6291959 DOI: 10.1016/0014-4827(82)90211-7 |
0.42 |
|
| 1979 |
Critchley DR, Ansell S, Perkins R, Dilks S, Ingram J. Isolation of cholera toxin receptors from a mouse fibroblast and lymphoid cell line by immune precipitation. Journal of Supramolecular Structure. 12: 273-91. PMID 544939 DOI: 10.1002/Jss.400120211 |
0.309 |
|
| 1979 |
Critchley DR, England MA, Wakely J, Hynes RO. Distribution of fibronectin in the ectoderm of gastrulating chick embryos Nature. 280: 498-500. PMID 379654 DOI: 10.1038/280498A0 |
0.309 |
|
| 1969 |
Millington PF, Critchley DR, Tovell PW, Pearson R. Scanning electron microscopy of intestinal microvilli. Journal of Microscopy. 89: 339-44. PMID 4184024 DOI: 10.1111/j.1365-2818.1969.tb00681.x |
0.617 |
|
| 1968 |
Millington PF, Critchley DR, Tovell PW. A study on the isolation of intestinal brush borders in saline. Zeitschrift Fur Zellforschung Und Mikroskopische Anatomie (Vienna, Austria : 1948). 87: 401-8. PMID 4974199 DOI: 10.1007/BF00333689 |
0.618 |
|
| 1968 |
Millington P, Critchley D. Lipid composition of the brush borders of rat intestinal epithelial cells Life Sciences. 7: 839-845. DOI: 10.1016/0024-3205(68)90157-4 |
0.634 |
|
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