Year |
Citation |
Score |
2022 |
Groelly FJ, Fawkes M, Dagg RA, Blackford AN, Tarsounas M. Targeting DNA damage response pathways in cancer. Nature Reviews. Cancer. 23: 78-94. PMID 36471053 DOI: 10.1038/s41568-022-00535-5 |
0.356 |
|
2022 |
Groelly FJ, Dagg RA, Petropoulos M, Rossetti GG, Prasad B, Panagopoulos A, Paulsen T, Karamichali A, Jones SE, Ochs F, Dionellis VS, Puig Lombardi E, Miossec MJ, Lockstone H, Legube G, ... Blackford AN, et al. Mitotic DNA synthesis is caused by transcription-replication conflicts in BRCA2-deficient cells. Molecular Cell. PMID 36002001 DOI: 10.1016/j.molcel.2022.07.011 |
0.433 |
|
2022 |
De Marco Zompit M, Esteban MT, Mooser C, Adam S, Rossi SE, Jeanrenaud A, Leimbacher PA, Fink D, Shorrocks AK, Blackford AN, Durocher D, Stucki M. The CIP2A-TOPBP1 complex safeguards chromosomal stability during mitosis. Nature Communications. 13: 4143. PMID 35842428 DOI: 10.1038/s41467-022-31865-5 |
0.662 |
|
2021 |
Shorrocks AK, Jones SE, Tsukada K, Morrow CA, Belblidia Z, Shen J, Vendrell I, Fischer R, Kessler BM, Blackford AN. The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forks. Nature Communications. 12: 585. PMID 33500419 DOI: 10.1038/s41467-020-20818-5 |
0.411 |
|
2020 |
Henssen AG, Koche R, Zhuang J, Jiang E, Reed C, Eisenberg A, Still E, MacArthur IC, Rodríguez-Fos E, Gonzalez S, Puiggròs M, Blackford AN, Mason CE, de Stanchina E, Gönen M, et al. Author Correction: PGBD5 promotes site-specific oncogenic mutations in human tumors. Nature Genetics. PMID 32918070 DOI: 10.1038/S41588-020-00711-Z |
0.416 |
|
2020 |
Ochi T, Quarantotti V, Lin H, Jullien J, Rosa E Silva I, Boselli F, Barnabas DD, Johnson CM, McLaughlin SH, Freund SMV, Blackford AN, Kimata Y, Goldstein RE, Jackson SP, Blundell TL, et al. CCDC61/VFL3 Is a Paralog of SAS6 and Promotes Ciliary Functions. Structure (London, England : 1993). PMID 32375023 DOI: 10.1016/J.Str.2020.04.010 |
0.448 |
|
2020 |
Blackford AN, Stucki M. How Cells Respond to DNA Breaks in Mitosis. Trends in Biochemical Sciences. PMID 32001093 DOI: 10.1016/j.tibs.2019.12.010 |
0.377 |
|
2020 |
Mooser C, Symeonidou IE, Leimbacher PA, Ribeiro A, Shorrocks AK, Jungmichel S, Larsen SC, Knechtle K, Jasrotia A, Zurbriggen D, Jeanrenaud A, Leikauf C, Fink D, Nielsen ML, Blackford AN, et al. Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation. Nature Communications. 11: 123. PMID 31913317 DOI: 10.1038/s41467-019-13981-x |
0.315 |
|
2019 |
Leimbacher PA, Jones SE, Shorrocks AK, de Marco Zompit M, Day M, Blaauwendraad J, Bundschuh D, Bonham S, Fischer R, Fink D, Kessler BM, Oliver AW, Pearl LH, Blackford AN, Stucki M. MDC1 Interacts with TOPBP1 to Maintain Chromosomal Stability during Mitosis. Molecular Cell. PMID 30898438 DOI: 10.1016/j.molcel.2019.02.014 |
0.467 |
|
2018 |
Becker JR, Cuella-Martin R, Barazas M, Liu R, Oliveira C, Oliver AW, Bilham K, Holt AB, Blackford AN, Heierhorst J, Jonkers J, Rottenberg S, Chapman JR. The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity. Nature Communications. 9: 5406. PMID 30559443 DOI: 10.1038/s41467-018-07855-x |
0.363 |
|
2017 |
Henssen AG, Koche R, Zhuang J, Jiang E, Reed C, Eisenberg A, Still E, MacArthur IC, Rodríguez-Fos E, Gonzalez S, Puiggròs M, Blackford AN, Mason CE, de Stanchina E, Gönen M, et al. Erratum: PGBD5 promotes site-specific oncogenic mutations in human tumors. Nature Genetics. 49: 1558. PMID 28951624 DOI: 10.1038/Ng1017-1558B |
0.411 |
|
2017 |
Sun L, Huang Y, Edwards RA, Yang S, Blackford AN, Niedzwiedz W, Glover JNM. Structural Insight into BLM Recognition by TopBP1. Structure (London, England : 1993). PMID 28919440 DOI: 10.1016/J.Str.2017.08.005 |
0.674 |
|
2017 |
Blackford AN, Jackson SP. ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response. Molecular Cell. 66: 801-817. PMID 28622525 DOI: 10.1016/j.molcel.2017.05.015 |
0.572 |
|
2017 |
Henssen AG, Koche R, Zhuang J, Jiang E, Reed C, Eisenberg A, Still E, MacArthur IC, Rodríguez-Fos E, Gonzalez S, Puiggròs M, Blackford AN, Mason CE, de Stanchina E, Gönen M, et al. PGBD5 promotes site-specific oncogenic mutations in human tumors. Nature Genetics. PMID 28504702 DOI: 10.1038/Ng.3866 |
0.56 |
|
2017 |
Henssen AG, Koche R, Zhuang J, Jiang E, Reed C, Eisenberg A, Still E, Rodríguez-Fos E, Gonzalez S, Puiggròs M, Blackford AN, Mason CE, Stanchina Ed, Gönen M, Emde A, et al. Abstract 4888: Human PGBD5 DNA transposase promotes site-specific oncogenic mutations in rhabdoid tumors Cancer Research. 77: 4888-4888. DOI: 10.1158/1538-7445.Am2017-4888 |
0.5 |
|
2017 |
Henssen A, Koche R, Zhuang J, Jiang E, Reed C, Eisenberg A, Still E, Rodríguez-Fos E, Gonzalez S, Puiggròs M, Blackford A, Mason C, Stanchina Ed, Gönen M, Emde A, et al. Human PGBD5 DNA transposase promotes site-specific oncogenic mutations in rhabdoid tumors Klinische Padiatrie. 229. DOI: 10.1055/S-0037-1602202 |
0.503 |
|
2016 |
Balmus G, Barros AC, Wijnhoven PW, Lescale C, Hasse HL, Boroviak K, le Sage C, Doe B, Speak AO, Galli A, Jacobsen M, Deriano L, Adams DJ, Blackford AN, Jackson SP. Synthetic lethality between PAXX and XLF in mammalian development. Genes & Development. 30: 2152-2157. PMID 27798842 DOI: 10.1101/Gad.290510.116 |
0.466 |
|
2016 |
Lescale C, Lenden Hasse H, Blackford AN, Balmus G, Bianchi JJ, Yu W, Bacoccina L, Jarade A, Clouin C, Sivapalan R, Reina-San-Martin B, Jackson SP, Deriano L. Specific Roles of XRCC4 Paralogs PAXX and XLF during V(D)J Recombination. Cell Reports. PMID 27601299 DOI: 10.1016/j.celrep.2016.08.069 |
0.56 |
|
2015 |
Harley ME, Murina O, Leitch A, Higgs MR, Bicknell LS, Yigit G, Blackford AN, Zlatanou A, Mackenzie KJ, Reddy K, Halachev M, McGlasson S, Reijns MA, Fluteau A, Martin CA, et al. TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism. Nature Genetics. PMID 26595769 DOI: 10.1038/Ng.3451 |
0.592 |
|
2015 |
Wijnhoven P, Konietzny R, Blackford AN, Travers J, Kessler BM, Nishi R, Jackson SP. USP4 Auto-Deubiquitylation Promotes Homologous Recombination. Molecular Cell. 60: 362-73. PMID 26455393 DOI: 10.1016/j.molcel.2015.09.019 |
0.609 |
|
2015 |
Higgs MR, Reynolds JJ, Winczura A, Blackford AN, Borel V, Miller ES, Zlatanou A, Nieminuszczy J, Ryan EL, Davies NJ, Stankovic T, Boulton SJ, Niedzwiedz W, Stewart GS. BOD1L Is Required to Suppress Deleterious Resection of Stressed Replication Forks. Molecular Cell. 59: 462-77. PMID 26166705 DOI: 10.1016/j.molcel.2015.06.007 |
0.726 |
|
2015 |
Blackford AN, Nieminuszczy J, Schwab RA, Galanty Y, Jackson SP, Niedzwiedz W. TopBP1 interacts with BLM to maintain genome stability but is dispensable for preventing BLM degradation. Molecular Cell. 57: 1133-41. PMID 25794620 DOI: 10.1016/j.molcel.2015.02.012 |
0.705 |
|
2015 |
Broderick R, Nieminuszczy J, Blackford AN, Winczura A, Niedzwiedz W. TOPBP1 recruits TOP2A to ultra-fine anaphase bridges to aid in their resolution. Nature Communications. 6: 6572. PMID 25762097 DOI: 10.1038/ncomms7572 |
0.68 |
|
2015 |
Ochi T, Blackford AN, Coates J, Jhujh S, Mehmood S, Tamura N, Travers J, Wu Q, Draviam VM, Robinson CV, Blundell TL, Jackson SP. DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair. Science (New York, N.Y.). 347: 185-8. PMID 25574025 DOI: 10.1126/Science.1261971 |
0.602 |
|
2012 |
Polo SE, Blackford AN, Chapman JR, Baskcomb L, Gravel S, Rusch A, Thomas A, Blundred R, Smith P, Kzhyshkowska J, Dobner T, Taylor AM, Turnell AS, Stewart GS, Grand RJ, et al. Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair. Molecular Cell. 45: 505-16. PMID 22365830 DOI: 10.1016/j.molcel.2011.12.035 |
0.685 |
|
2012 |
Blackford AN, Schwab RA, Nieminuszczy J, Deans AJ, West SC, Niedzwiedz W. The DNA translocase activity of FANCM protects stalled replication forks. Human Molecular Genetics. 21: 2005-16. PMID 22279085 DOI: 10.1093/Hmg/Dds013 |
0.723 |
|
2011 |
Forrester NA, Sedgwick GG, Thomas A, Blackford AN, Speiseder T, Dobner T, Byrd PJ, Stewart GS, Turnell AS, Grand RJ. Serotype-specific inactivation of the cellular DNA damage response during adenovirus infection. Journal of Virology. 85: 2201-11. PMID 21159879 DOI: 10.1128/JVI.01748-10 |
0.476 |
|
2011 |
Blackford AN, Stewart GS. When cleavage is not attractive: non-catalytic inhibition of ubiquitin chains at DNA double-strand breaks by OTUB1. Dna Repair. 10: 245-9. PMID 21130715 DOI: 10.1016/j.dnarep.2010.11.004 |
0.333 |
|
2010 |
Blackford AN, Patel RN, Forrester NA, Theil K, Groitl P, Stewart GS, Taylor AM, Morgan IM, Dobner T, Grand RJ, Turnell AS. Adenovirus 12 E4orf6 inhibits ATR activation by promoting TOPBP1 degradation. Proceedings of the National Academy of Sciences of the United States of America. 107: 12251-6. PMID 20566845 DOI: 10.1073/pnas.0914605107 |
0.462 |
|
2010 |
Blackford AN, Schwab RA, Niedzwiedz W. A novel ATRibute of FANCM. Cell Cycle (Georgetown, Tex.). 9: 1453-5. PMID 20372056 |
0.584 |
|
2010 |
Schwab RA, Blackford AN, Niedzwiedz W. ATR activation and replication fork restart are defective in FANCM-deficient cells. The Embo Journal. 29: 806-18. PMID 20057355 DOI: 10.1038/emboj.2009.385 |
0.726 |
|
2009 |
Townsend K, Mason H, Blackford AN, Miller ES, Chapman JR, Sedgwick GG, Barone G, Turnell AS, Stewart GS. Mediator of DNA damage checkpoint 1 (MDC1) regulates mitotic progression. The Journal of Biological Chemistry. 284: 33939-48. PMID 19826003 DOI: 10.1074/jbc.M109.009191 |
0.362 |
|
2009 |
Blackford AN, Grand RJ. Adenovirus E1B 55-kilodalton protein: multiple roles in viral infection and cell transformation. Journal of Virology. 83: 4000-12. PMID 19211739 DOI: 10.1128/JVI.02417-08 |
0.44 |
|
2009 |
Shimwell NJ, Martin A, Bruton RK, Blackford AN, Sedgwick GG, Gallimore PH, Turnell AS, Grand RJ. Adenovirus 5 E1A is responsible for increased expression of insulin receptor substrate 4 in established adenovirus 5-transformed cell lines and interacts with IRS components activating the PI3 kinase/Akt signalling pathway. Oncogene. 28: 686-97. PMID 19029952 DOI: 10.1038/onc.2008.417 |
0.459 |
|
2008 |
Blackford AN, Bruton RK, Dirlik O, Stewart GS, Taylor AM, Dobner T, Grand RJ, Turnell AS. A role for E1B-AP5 in ATR signaling pathways during adenovirus infection. Journal of Virology. 82: 7640-52. PMID 18480432 DOI: 10.1128/JVI.00170-08 |
0.517 |
|
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