| Year |
Citation |
Score |
| 2024 |
Aubrey LD, Ninkina N, Ulamec SM, Abramycheva NY, Vasili E, Devine OM, Wilkinson M, Mackinnon E, Limorenko G, Walko M, Muwanga S, Amadio L, Peters OM, Illarioshkin SN, Outeiro TF, ... ... Brockwell DJ, et al. Substitution of Met-38 to Ile in γ-synuclein found in two patients with amyotrophic lateral sclerosis induces aggregation into amyloid. Proceedings of the National Academy of Sciences of the United States of America. 121: e2309700120. PMID 38170745 DOI: 10.1073/pnas.2309700120 |
0.494 |
|
| 2023 |
Berhanu S, Majumder S, Müntener T, Whitehouse J, Berner C, Bera AK, Kang A, Liang B, Khan GN, Sankaran B, Tamm LK, Brockwell DJ, Hiller S, Radford SE, Baker D, et al. Sculpting conducting nanopore size and shape through protein design. Biorxiv : the Preprint Server For Biology. PMID 38187764 DOI: 10.1101/2023.12.20.572500 |
0.482 |
|
| 2023 |
Laurent H, Hughes MDG, Walko M, Brockwell DJ, Mahmoudi N, Youngs TGA, Headen TF, Dougan L. Visualization of Self-Assembly and Hydration of a β-Hairpin through Integrated Small and Wide-Angle Neutron Scattering. Biomacromolecules. PMID 37874935 DOI: 10.1021/acs.biomac.3c00583 |
0.622 |
|
| 2023 |
Hughes MDG, Cussons S, Hanson BS, Cook KR, Feller T, Mahmoudi N, Baker DL, Ariëns R, Head DA, Brockwell DJ, Dougan L. Building block aspect ratio controls assembly, architecture, and mechanics of synthetic and natural protein networks. Nature Communications. 14: 5593. PMID 37696784 DOI: 10.1038/s41467-023-40921-7 |
0.668 |
|
| 2023 |
Aufderhorst-Roberts A, Cussons S, Brockwell DJ, Dougan L. Diversity of viscoelastic properties of an engineered muscle-inspired protein hydrogel. Soft Matter. 19: 3167-3178. PMID 37067782 DOI: 10.1039/d2sm01225a |
0.681 |
|
| 2023 |
Brown CP, Hughes MDG, Mahmoudi N, Brockwell DJ, Coletta PL, Peyman S, Evans SD, Dougan L. Structural and mechanical properties of folded protein hydrogels with embedded microbubbles. Biomaterials Science. PMID 36815670 DOI: 10.1039/d2bm01918c |
0.7 |
|
| 2023 |
J E Bruce A, Paci E, Brockwell DJ. Collagen-like motifs of SasG: a novel fold for protein mechanical strength. Journal of Molecular Biology. 167980. PMID 36708761 DOI: 10.1016/j.jmb.2023.167980 |
0.358 |
|
| 2022 |
Ulamec SM, Maya-Martinez R, Byrd EJ, Dewison KM, Xu Y, Willis LF, Sobott F, Heath GR, van Oosten Hawle P, Buchman VL, Radford SE, Brockwell DJ. Single residue modulators of amyloid formation in the N-terminal P1-region of α-synuclein. Nature Communications. 13: 4986. PMID 36008493 DOI: 10.1038/s41467-022-32687-1 |
0.471 |
|
| 2022 |
Hughes MDG, Cussons S, Mahmoudi N, Brockwell DJ, Dougan L. Tuning Protein Hydrogel Mechanics through Modulation of Nanoscale Unfolding and Entanglement in Postgelation Relaxation. Acs Nano. PMID 35731007 DOI: 10.1021/acsnano.2c02369 |
0.737 |
|
| 2022 |
Schiffrin B, Machin JM, Karamanos TK, Zhuravleva A, Brockwell DJ, Radford SE, Calabrese AN. Dynamic interplay between the periplasmic chaperone SurA and the BAM complex in outer membrane protein folding. Communications Biology. 5: 560. PMID 35676411 DOI: 10.1038/s42003-022-03502-w |
0.543 |
|
| 2021 |
White P, Haysom SF, Iadanza MG, Higgins AJ, Machin JM, Whitehouse JM, Horne JE, Schiffrin B, Carpenter-Platt C, Calabrese AN, Storek KM, Rutherford ST, Brockwell DJ, Ranson NA, Radford SE. The role of membrane destabilisation and protein dynamics in BAM catalysed OMP folding. Nature Communications. 12: 4174. PMID 34234105 DOI: 10.1038/s41467-021-24432-x |
0.535 |
|
| 2021 |
Hughes MDG, Hanson BS, Cussons S, Mahmoudi N, Brockwell DJ, Dougan L. Control of Nanoscale Protein Unfolding Defines Network Architecture and Mechanics of Protein Hydrogels. Acs Nano. PMID 34214394 DOI: 10.1021/acsnano.1c00353 |
0.738 |
|
| 2021 |
Vorobieva AA, White P, Liang B, Horne JE, Bera AK, Chow CM, Gerben S, Marx S, Kang A, Stiving AQ, Harvey SR, Marx DC, Khan GN, Fleming KG, Wysocki VH, ... Brockwell DJ, et al. De novo design of transmembrane β barrels. Science (New York, N.Y.). 371. PMID 33602829 DOI: 10.1126/science.abc8182 |
0.484 |
|
| 2020 |
Willis LF, Kumar A, Jain T, Caffry I, Xu Y, Radford SE, Kapur N, Vásquez M, Brockwell DJ. The uniqueness of flow in probing the aggregation behavior of clinically relevant antibodies. Engineering Reports : Open Access. 2: e12147. PMID 34901768 DOI: 10.1002/eng2.12147 |
0.5 |
|
| 2020 |
Ulamec SM, Brockwell DJ, Radford SE. Looking Beyond the Core: The Role of Flanking Regions in the Aggregation of Amyloidogenic Peptides and Proteins. Frontiers in Neuroscience. 14: 611285. PMID 33335475 DOI: 10.3389/fnins.2020.611285 |
0.534 |
|
| 2020 |
Iadanza MG, Schiffrin B, White P, Watson MA, Horne JE, Higgins AJ, Calabrese AN, Brockwell DJ, Tuma R, Kalli AC, Radford SE, Ranson NA. Distortion of the bilayer and dynamics of the BAM complex in lipid nanodiscs. Communications Biology. 3: 766. PMID 33318620 DOI: 10.1038/s42003-020-01419-w |
0.516 |
|
| 2020 |
Aufderhorst-Roberts A, Hughes M, Hare A, Head DA, Kapur N, Brockwell DJ, Dougan L. Reaction Rate Governs the Viscoelasticity and Nanostructure of Folded Protein Hydrogels. Biomacromolecules. PMID 32870660 DOI: 10.1021/Acs.Biomac.0C01044 |
0.647 |
|
| 2020 |
Hughes MDG, Cussons S, Mahmoudi N, Brockwell DJ, Dougan L. Single molecule protein stabilisation translates to macromolecular mechanics of a protein network. Soft Matter. PMID 32578583 DOI: 10.1039/C9Sm02484K |
0.746 |
|
| 2020 |
Schiffrin B, Radford SE, Brockwell DJ, Calabrese AN. PyXlinkViewer: a flexible tool for visualisation of protein chemical crosslinking data within the PyMOL molecular graphics system. Protein Science : a Publication of the Protein Society. PMID 32557917 DOI: 10.1002/pro.3902 |
0.529 |
|
| 2020 |
Horne JE, Brockwell DJ, Radford SE. Role of the lipid bilayer in outer membrane protein folding in Gram-negative bacteria. The Journal of Biological Chemistry. 295: 10340-10367. PMID 32499369 DOI: 10.1074/jbc.REV120.011473 |
0.537 |
|
| 2020 |
Calabrese AN, Schiffrin B, Watson M, Karamanos TK, Walko M, Humes JR, Horne JE, White P, Wilson AJ, Kalli AC, Tuma R, Ashcroft AE, Brockwell DJ, Radford SE. Inter-domain dynamics in the chaperone SurA and multi-site binding to its outer membrane protein clients. Nature Communications. 11: 2155. PMID 32358557 DOI: 10.1038/S41467-020-15702-1 |
0.755 |
|
| 2020 |
Ebo JS, Saunders JC, Devine PWA, Gordon AM, Warwick AS, Schiffrin B, Chin SE, England E, Button JD, Lloyd C, Bond NJ, Ashcroft AE, Radford SE, Lowe DC, Brockwell DJ. An in vivo platform to select and evolve aggregation-resistant proteins. Nature Communications. 11: 1816. PMID 32286330 DOI: 10.1038/s41467-020-15667-1 |
0.53 |
|
| 2020 |
Doherty CPA, Ulamec SM, Maya-Martinez R, Good SC, Makepeace J, Khan GN, van Oosten-Hawle P, Radford SE, Brockwell DJ. A short motif in the N-terminal region of α-synuclein is critical for both aggregation and function. Nature Structural & Molecular Biology. 27: 249-259. PMID 32157247 DOI: 10.1038/s41594-020-0384-x |
0.474 |
|
| 2020 |
Ebo JS, Guthertz N, Radford SE, Brockwell DJ. Using protein engineering to understand and modulate aggregation. Current Opinion in Structural Biology. 60: 157-166. PMID 32087409 DOI: 10.1016/j.sbi.2020.01.005 |
0.604 |
|
| 2020 |
Willis LF, Kumar A, Jain T, Caffry I, Xu Y, Radford SE, Kapur N, Vásquez M, Brockwell DJ. The uniqueness of flow in probing the aggregation behavior of clinically relevant antibodies Engineering Reports. 2. DOI: 10.1002/eng2.12147 |
0.394 |
|
| 2019 |
Humes JR, Schiffrin B, Calabrese AN, Higgins AJ, Westhead DR, Brockwell DJ, Radford SE. The Role of SurA PPIase Domains in Preventing Aggregation of the Outer Membrane Proteins tOmpA and OmpT. Journal of Molecular Biology. PMID 30716334 DOI: 10.1016/j.jmb.2019.01.032 |
0.495 |
|
| 2018 |
Horne J, Walko M, Calabrese A, Levenstein M, Brockwell D, Kapur N, Wilson A, Radford SE. Rapid Mapping of Protein Interactions Using Tag-Transfer Photocrosslinkers. Angewandte Chemie (International Ed. in English). PMID 30393918 DOI: 10.1002/Anie.201809149 |
0.528 |
|
| 2018 |
Doherty CPA, Young LM, Karamanos TK, Smith HI, Jackson MP, Radford SE, Brockwell DJ. A peptide-display protein scaffold to facilitate single molecule force studies of aggregation-prone peptides. Protein Science : a Publication of the Protein Society. PMID 29417650 DOI: 10.1002/pro.3386 |
0.792 |
|
| 2018 |
Willis LF, Kumar A, Dobson J, Bond N, Lowe D, Turner R, Radford SE, Kapur N, Brockwell DJ. Using extensional flow to reveal diverse aggregation landscapes for three IgG1 molecules. Biotechnology and Bioengineering. PMID 29315487 DOI: 10.1002/bit.26543 |
0.46 |
|
| 2017 |
Schiffrin B, Brockwell DJ, Radford SE. Outer membrane protein folding from an energy landscape perspective. Bmc Biology. 15: 123. PMID 29268734 DOI: 10.1186/s12915-017-0464-5 |
0.562 |
|
| 2017 |
Schiffrin B, Calabrese AN, Higgins AJ, Humes JR, Ashcroft AE, Kalli AC, Brockwell DJ, Radford SE. Effects of periplasmic chaperones and membrane thickness on BamA-catalysed outer membrane protein folding. Journal of Molecular Biology. PMID 28919234 DOI: 10.1016/j.jmb.2017.09.008 |
0.519 |
|
| 2017 |
Hickman SJ, Cooper REM, Bellucci L, Paci E, Brockwell DJ. Gating of TonB-dependent transporters by substrate-specific forced remodelling. Nature Communications. 8: 14804. PMID 28429713 DOI: 10.1038/ncomms14804 |
0.342 |
|
| 2017 |
Dobson J, Kumar A, Willis LF, Tuma R, Higazi DR, Turner R, Lowe DC, Ashcroft AE, Radford SE, Kapur N, Brockwell DJ. Inducing protein aggregation by extensional flow. Proceedings of the National Academy of Sciences of the United States of America. PMID 28416674 DOI: 10.1073/pnas.1702724114 |
0.544 |
|
| 2017 |
Horne JE, Brockwell DJ, Radford SE. Fretting about Outer Membrane Protein Biogenesis. How Exactly do they Fold? Biophysical Journal. 112: 205a. DOI: 10.1016/J.BPJ.2016.11.1131 |
0.54 |
|
| 2016 |
da Silva MA, Lenton S, Hughes M, Brockwell DJ, Dougan L. Assessing the potential of folded globular polyproteins as hydrogel building blocks. Biomacromolecules. PMID 28006103 DOI: 10.1021/Acs.Biomac.6B01877 |
0.712 |
|
| 2016 |
Iadanza MG, Higgins AJ, Schiffrin B, Calabrese AN, Brockwell DJ, Ashcroft AE, Radford SE, Ranson NA. Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM. Nature Communications. 7: 12865. PMID 27686148 DOI: 10.1038/Ncomms12865 |
0.543 |
|
| 2016 |
Schiffrin B, Calabrese AN, Devine PW, Harris SA, Ashcroft AE, Brockwell DJ, Radford SE. Skp is a multivalent chaperone of outer-membrane proteins. Nature Structural & Molecular Biology. PMID 27455461 DOI: 10.1038/nsmb.3266 |
0.573 |
|
| 2016 |
Tych KM, Batchelor M, Hoffmann T, Wilson MC, Hughes ML, Paci E, Brockwell DJ, Dougan L. Differential effects of hydrophobic core packing residues for thermodynamic and mechanical stability of a hyperthermophilic protein. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 27338140 DOI: 10.1021/Acs.Langmuir.6B01550 |
0.819 |
|
| 2016 |
Tych KM, Batchelor M, Hoffmann T, Wilson MC, Paci E, Brockwell DJ, Dougan L. Tuning protein mechanics through an ionic cluster graft from an extremophilic protein. Soft Matter. PMID 26809452 DOI: 10.1039/C5Sm02938D |
0.827 |
|
| 2015 |
Saunders JC, Young LM, Mahood RA, Jackson MP, Revill CH, Foster RJ, Smith DA, Ashcroft AE, Brockwell DJ, Radford SE. An in vivo platform for identifying inhibitors of protein aggregation. Nature Chemical Biology. PMID 26656088 DOI: 10.1038/nchembio.1988 |
0.534 |
|
| 2015 |
Hoffmann T, Tych KM, Crosskey T, Schiffrin B, Brockwell DJ, Dougan L. Rapid and Robust Polyprotein Production Facilitates Single-Molecule Mechanical Characterization of β-Barrel Assembly Machinery Polypeptide Transport Associated Domains. Acs Nano. 9: 8811-21. PMID 26284289 DOI: 10.1021/Acsnano.5B01962 |
0.797 |
|
| 2015 |
Gruszka DT, Whelan F, Farrance OE, Fung HK, Paci E, Jeffries CM, Svergun DI, Baldock C, Baumann CG, Brockwell DJ, Potts JR, Clarke J. Cooperative folding of intrinsically disordered domains drives assembly of a strong elongated protein. Nature Communications. 6: 7271. PMID 26027519 DOI: 10.1038/Ncomms8271 |
0.326 |
|
| 2015 |
Tych KM, Hoffmann T, Batchelor M, Hughes ML, Kendrick KE, Walsh DL, Wilson M, Brockwell DJ, Dougan L. Life in extreme environments: single molecule force spectroscopy as a tool to explore proteins from extremophilic organisms. Biochemical Society Transactions. 43: 179-85. PMID 25849914 DOI: 10.1042/Bst20140274 |
0.807 |
|
| 2015 |
Chen Y, Radford SE, Brockwell DJ. Force-induced remodelling of proteins and their complexes. Current Opinion in Structural Biology. 30: 89-99. PMID 25710390 DOI: 10.1016/j.sbi.2015.02.001 |
0.576 |
|
| 2015 |
Tych KM, Hughes ML, Bourke J, Taniguchi Y, Kawakami M, Brockwell DJ, Dougan L. Optimizing the calculation of energy landscape parameters from single-molecule protein unfolding experiments. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 91: 012710. PMID 25679645 DOI: 10.1103/Physreve.91.012710 |
0.795 |
|
| 2015 |
Farrance OE, Paci E, Radford SE, Brockwell DJ. Extraction of accurate biomolecular parameters from single-molecule force spectroscopy experiments. Acs Nano. 9: 1315-24. PMID 25646767 DOI: 10.1021/nn505135d |
0.522 |
|
| 2014 |
McMorran LM, Brockwell DJ, Radford SE. Mechanistic studies of the biogenesis and folding of outer membrane proteins in vitro and in vivo: what have we learned to date? Archives of Biochemistry and Biophysics. 564: 265-80. PMID 24613287 DOI: 10.1016/j.abb.2014.02.011 |
0.597 |
|
| 2014 |
Farrance OE, Kaminska R, Housden NG, Derrington SR, Kleanthous C, Radford SE, Brockwell DJ. Investigating Protein-Protein Interaction Networks with Force Spectroscopy Biophysical Journal. 106: 385a-386a. DOI: 10.1016/J.BPJ.2013.11.2181 |
0.586 |
|
| 2013 |
Hoffmann T, Tych KM, Hughes ML, Brockwell DJ, Dougan L. Towards design principles for determining the mechanical stability of proteins. Physical Chemistry Chemical Physics : Pccp. 15: 15767-80. PMID 23989058 DOI: 10.1039/C3Cp52142G |
0.82 |
|
| 2013 |
McMorran LM, Bartlett AI, Huysmans GH, Radford SE, Brockwell DJ. Dissecting the effects of periplasmic chaperones on the in vitro folding of the outer membrane protein PagP. Journal of Molecular Biology. 425: 3178-91. PMID 23796519 DOI: 10.1016/j.jmb.2013.06.017 |
0.541 |
|
| 2013 |
Farrance OE, Hann E, Kaminska R, Housden NG, Derrington SR, Kleanthous C, Radford SE, Brockwell DJ. A force-activated trip switch triggers rapid dissociation of a colicin from its immunity protein. Plos Biology. 11: e1001489. PMID 23431269 DOI: 10.1371/journal.pbio.1001489 |
0.562 |
|
| 2013 |
Hoffmann T, Tych KM, Brockwell DJ, Dougan L. Single-molecule force spectroscopy identifies a small cold shock protein as being mechanically robust. The Journal of Physical Chemistry. B. 117: 1819-26. PMID 23293964 DOI: 10.1021/Jp310442S |
0.838 |
|
| 2013 |
Tych KM, Hoffmann T, Brockwell DJ, Dougan L. Single molecule force spectroscopy reveals the temperature-dependent robustness and malleability of a hyperthermophilic protein† Soft Matter. 9: 9016-9025. DOI: 10.1039/C3Sm51439K |
0.812 |
|
| 2013 |
Brockwell D, Farrance O, Kaminska R, Derrington S, Kleanthous C, Radford S. Force Triggered Dissociation of the Highly Avid E9:Im9 Complex Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.3174 |
0.607 |
|
| 2012 |
Ikeda-Kobayashi A, Taniguchi Y, Brockwell DJ, Paci E, Kawakami M. Prying open single GroES ring complexes by force reveals cooperativity across domains. Biophysical Journal. 102: 1961-8. PMID 22768953 DOI: 10.1016/j.bpj.2012.03.046 |
0.385 |
|
| 2012 |
Huysmans GHM, Radford SE, Baldwin SA, Brockwell DJ. Malleability of the folding mechanism of the outer membrane protein PagP: Parallel pathways and the effect of membrane elasticity Journal of Molecular Biology. 416: 453-464. PMID 22245579 DOI: 10.1016/j.jmb.2011.12.039 |
0.554 |
|
| 2011 |
Crampton N, Alzahrani K, Beddard GS, Connell SD, Brockwell DJ. Mechanically unfolding protein L using a laser-feedback-controlled cantilever. Biophysical Journal. 100: 1800-9. PMID 21463594 DOI: 10.1016/J.Bpj.2011.02.021 |
0.384 |
|
| 2010 |
Crampton N, Brockwell DJ. Unravelling the design principles for single protein mechanical strength. Current Opinion in Structural Biology. 20: 508-17. PMID 20542682 DOI: 10.1016/j.sbi.2010.05.005 |
0.471 |
|
| 2010 |
Pugh SD, Gell C, Smith DA, Radford SE, Brockwell DJ. Single-molecule studies of the Im7 folding landscape. Journal of Molecular Biology. 398: 132-45. PMID 20211187 DOI: 10.1016/j.jmb.2010.02.048 |
0.508 |
|
| 2010 |
Huysmans GHM, Baldwin SA, Brockwell DJ, Radford SE. The transition state for folding of an outer membrane protein Proceedings of the National Academy of Sciences of the United States of America. 107: 4099-4104. PMID 20133664 DOI: 10.1073/pnas.0911904107 |
0.586 |
|
| 2009 |
Beddard GS, Brockwell DJ. A statistical approach to the estimation of mechanical unfolding parameters from the unfolding patterns of protein heteropolymers. Physical Biology. 7: 14001. PMID 20009191 DOI: 10.1088/1478-3975/7/1/014001 |
0.356 |
|
| 2009 |
Grant CA, Brockwell DJ, Radford SE, Thomson NH. Tuning the elastic modulus of hydrated collagen fibrils. Biophysical Journal. 97: 2985-92. PMID 19948128 DOI: 10.1016/j.bpj.2009.09.010 |
0.47 |
|
| 2009 |
Sadler DP, Petrik E, Taniguchi Y, Pullen JR, Kawakami M, Radford SE, Brockwell DJ. Identification of a mechanical rheostat in the hydrophobic core of protein L. Journal of Molecular Biology. 393: 237-48. PMID 19683005 DOI: 10.1016/j.jmb.2009.08.015 |
0.606 |
|
| 2009 |
Kawakami M, Taniguchi Y, Brockwell D. 2SP5-02 Quantitative detection of the internal fluctuation of proteins by AFM(2SP5 How are biological molecules fluctuating?,The 47th Annual Meeting of the Biophysical Society of Japan) Seibutsu Butsuri. 49. DOI: 10.2142/Biophys.49.S13_6 |
0.332 |
|
| 2009 |
Brockwell D. 11:30 Wednesday 1st July 2009Development of a tractable model for membrane protein folding Comparative Biochemistry and Physiology a-Molecular & Integrative Physiology. 153. DOI: 10.1016/J.Cbpa.2009.04.322 |
0.411 |
|
| 2008 |
Khatri BS, Byrne K, Kawakami M, Brockwell DJ, Smith DA, Radford SE, McLeish TC. Internal friction of single polypeptide chains at high stretch. Faraday Discussions. 139: 35-51; discussion 10. PMID 19048989 DOI: 10.1039/b716418c |
0.5 |
|
| 2008 |
Brockwell DJ. Probing the mechanical stability of proteins using the atomic force microscope. Biochemical Society Transactions. 35: 1564-8. PMID 18031267 DOI: 10.1042/BST0351564 |
0.454 |
|
| 2008 |
Grant CA, Brockwell DJ, Radford SE, Thomson NH. Effects of hydration on the mechanical response of individual collagen fibrils Applied Physics Letters. 92. DOI: 10.1063/1.2937001 |
0.453 |
|
| 2007 |
Huysmans GHM, Radford SE, Brockwell DJ, Baldwin SA. The N-terminal Helix Is a Post-assembly Clamp in the Bacterial Outer Membrane Protein PagP Journal of Molecular Biology. 373: 529-540. PMID 17868697 DOI: 10.1016/j.jmb.2007.07.072 |
0.522 |
|
| 2007 |
Hann E, Kirkpatrick N, Kleanthous C, Smith DA, Radford SE, Brockwell DJ. The effect of protein complexation on the mechanical stability of Im9. Biophysical Journal. 92: L79-81. PMID 17351013 DOI: 10.1529/biophysj.106.102475 |
0.57 |
|
| 2007 |
Brockwell DJ, Radford SE. Intermediates: ubiquitous species on folding energy landscapes? Current Opinion in Structural Biology. 17: 30-7. PMID 17239580 DOI: 10.1016/j.sbi.2007.01.003 |
0.572 |
|
| 2007 |
Brockwell DJ. Force Denaturation of Proteins - an Unfolding Story Current Nanoscience. 3: 3-15. DOI: 10.2174/157341307779940634 |
0.4 |
|
| 2006 |
West DK, Brockwell DJ, Paci E. Prediction of the translocation kinetics of a protein from its mechanical properties. Biophysical Journal. 91: L51-3. PMID 16815903 DOI: 10.1529/biophysj.106.089490 |
0.469 |
|
| 2006 |
Tezuka-Kawakami T, Gell C, Brockwell DJ, Radford SE, Smith DA. Urea-induced unfolding of the immunity protein Im9 monitored by spFRET. Biophysical Journal. 91: L42-4. PMID 16798813 DOI: 10.1529/biophysj.106.088344 |
0.523 |
|
| 2006 |
Kawakami M, Byrne K, Brockwell DJ, Radford SE, Smith DA. Viscoelastic study of the mechanical unfolding of a protein by AFM. Biophysical Journal. 91: L16-8. PMID 16698787 DOI: 10.1529/biophysj.106.085019 |
0.602 |
|
| 2006 |
West DK, Brockwell DJ, Olmsted PD, Radford SE, Paci E. Mechanical resistance of proteins explained using simple molecular models. Biophysical Journal. 90: 287-97. PMID 16214858 DOI: 10.1529/Biophysj.105.071035 |
0.612 |
|
| 2005 |
Brockwell DJ, Beddard GS, Paci E, West DK, Olmsted PD, Smith DA, Radford SE. Mechanically unfolding the small, topologically simple protein L. Biophysical Journal. 89: 506-19. PMID 15863479 DOI: 10.1529/Biophysj.105.061465 |
0.616 |
|
| 2003 |
Brockwell DJ, Paci E, Zinober RC, Beddard GS, Olmsted PD, Smith DA, Perham RN, Radford SE. Pulling geometry defines the mechanical resistance of a beta-sheet protein. Nature Structural Biology. 10: 731-7. PMID 12923573 DOI: 10.1038/Nsb968 |
0.709 |
|
| 2003 |
Smith DA, Brockwell DJ, Zinober RC, Blake AW, Beddard GS, Olmsted PD, Radford SE. Unfolding dynamics of proteins under applied force. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 361: 713-28; discussion 7. PMID 12871620 DOI: 10.1098/Rsta.2002.1160 |
0.643 |
|
| 2003 |
Paliy O, Bloor D, Brockwell D, Gilbert P, Barber J. Improved methods of cultivation and production of deuteriated proteins from E. coli strains grown on fully deuteriated minimal medium Journal of Applied Microbiology. 94: 580-586. PMID 12631193 DOI: 10.1046/J.1365-2672.2003.01866.X |
0.587 |
|
| 2003 |
Alastair Smith D, Brockwell DJ, Zinober RC, Blake AW, Beddard GS, Olmsted PD, Radford SE, Coffey WT, Sackmann E, Felderhof BU, Maaloum M, Titmuss S, Crothers DSF, Bartlett P. Unfolding dynamics of proteins under applied force Philosophical Transactions of the Royal Society a: Mathematical, Physical and Engineering Sciences. 361: 713-730. DOI: 10.1098/rsta.2002.1160 |
0.577 |
|
| 2003 |
Brockwell DJ, Paci E, Zinober RC, Beddard GS, Olmsted PD, Smith DA, Perham RN, Radford SE. Erratum: Pulling geometry defines the mechanical resistance of a β-sheet protein Nature Structural & Molecular Biology. 10: 872-872. DOI: 10.1038/Nsb1003-872B |
0.463 |
|
| 2003 |
Best RB, Brockwell DJ, Toca-Herrera JL, Blake AW, Smith D, Radford SE, Clarke J. Force mode atomic force microscopy as a tool for protein folding studies Analytica Chimica Acta. 479: 87-105. DOI: 10.1016/S0003-2670(02)01572-6 |
0.563 |
|
| 2002 |
Zinober RC, Brockwell DJ, Beddard GS, Blake AW, Olmsted PD, Radford SE, Smith DA. Mechanically unfolding proteins: the effect of unfolding history and the supramolecular scaffold. Protein Science : a Publication of the Protein Society. 11: 2759-65. PMID 12441375 DOI: 10.1110/Ps.0224602 |
0.559 |
|
| 2002 |
Brockwell DJ, Beddard GS, Clarkson J, Zinober RC, Blake AW, Trinick J, Olmsted PD, Smith DA, Radford SE. The effect of core destabilization on the mechanical resistance of I27. Biophysical Journal. 83: 458-72. PMID 12080133 DOI: 10.1016/S0006-3495(02)75182-5 |
0.538 |
|
| 2001 |
Brockwell D, Yu L, Cooper S, McCleland S, Cooper A, Attwood D, Gaskell SJ, Barber J. Physicochemical consequences of the perdeuteriation of glutathione S-transferase from S. japonicum. Protein Science : a Publication of the Protein Society. 10: 572-80. PMID 11344325 DOI: 10.1110/Ps.46001 |
0.68 |
|
| 2001 |
Gell C, Brockwell DJ, Beddard GS, Radford SE, Kalverda AP, Smith DA. Accurate Use of Single Molecule Fluorescence Correlation Spectroscopy to Determine Molecular Diffusion Times Single Molecules. 2: 177-181. DOI: 10.1002/1438-5171(200110)2:3<177::Aid-Simo177>3.0.Co;2-4 |
0.42 |
|
| 2000 |
Brockwell DJ, Smith DA, Radford SE. Protein folding mechanisms: new methods and emerging ideas. Current Opinion in Structural Biology. 10: 16-25. PMID 10679463 DOI: 10.1016/S0959-440X(99)00043-3 |
0.559 |
|
| 2000 |
Brockwell D, Clarkson J, Smith A, Radford S. Towards single molecule unfolding of proteins using AFM and its observation using fluorescence Biochemical Society Transactions. 28. DOI: 10.1042/Bst028A069A |
0.592 |
|
| 1998 |
Cooper SJ, Raftery J, Helliwell JR, Brockwell D, Attwood D, Barber J. The X-ray crystal structures of perdeuteriated and protiated enzyme elongation factor Tu are very similar Chemical Communications. 1063-1064. DOI: 10.1039/A801152D |
0.557 |
|
| 1997 |
Brockwell DJ, Marks DS, Barber J. Structural investigations of kirromycin bound to bacterial elongation factor Tu by NMR and molecular dynamics Biochemical Society Transactions. 25. PMID 9450040 DOI: 10.1042/Bst025S612 |
0.545 |
|
| Show low-probability matches. |