Yixian Zheng - Publications

Johns Hopkins University, Baltimore, MD 
Cell biology

86 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Vahabikashi A, Sivagurunathan S, Nicdao FAS, Han YL, Park CY, Kittisopikul M, Wong X, Tran JR, Gundersen GG, Reddy KL, Luxton GWG, Guo M, Fredberg JJ, Zheng Y, Adam SA, et al. Nuclear lamin isoforms differentially contribute to LINC complex-dependent nucleocytoskeletal coupling and whole-cell mechanics. Proceedings of the National Academy of Sciences of the United States of America. 119: e2121816119. PMID 35439057 DOI: 10.1073/pnas.2121816119  0.346
2020 Hu M, Zheng X, Fan CM, Zheng Y. Lineage dynamics of the endosymbiotic cell type in the soft coral Xenia. Nature. PMID 32555454 DOI: 10.1038/S41586-020-2385-7  0.365
2019 Xiao Y, Chen J, Wan Y, Gao Q, Jing N, Zheng Y, Zhu X. Regulation of zebrafish dorsoventral patterning by phase separation of RNA-binding protein Rbm14. Cell Discovery. 5: 37. PMID 31636951 DOI: 10.1038/S41421-019-0106-X  0.3
2019 Tiwary AK, Zheng Y. Protein phase separation in mitosis. Current Opinion in Cell Biology. 60: 92-98. PMID 31176175 DOI: 10.1016/J.Ceb.2019.04.011  0.301
2019 Liu W, Yue S, Zheng X, Hu M, Cao J, Zheng Y. aFARP-ChIP-seq, a convenient and reliable method for genome profiling in as few as 100 cells with a capability for multiplexing ChIP-seq. Epigenetics. 1-17. PMID 31169445 DOI: 10.1080/15592294.2019.1621139  0.355
2019 Yue S, Zheng X, Zheng Y. Cell-type-specific role of lamin-B1 in thymus development and its inflammation-driven reduction in thymus aging. Aging Cell. e12952. PMID 30968547 DOI: 10.1111/Acel.12952  0.395
2019 Kim Y, Zheng X, Zheng Y. Role of lamins in 3D genome organization and global gene expression. Nucleus (Austin, Tex.). 10: 33-41. PMID 30755082 DOI: 10.1080/19491034.2019.1578601  0.327
2018 Zheng X, Hu J, Yue S, Kristiani L, Kim M, Sauria M, Taylor J, Kim Y, Zheng Y. Lamins Organize the Global Three-Dimensional Genome from the Nuclear Periphery. Molecular Cell. 71: 802-815.e7. PMID 30201095 DOI: 10.1016/J.Molcel.2018.05.017  0.34
2017 Huang Y, Li T, Ems-McClung SC, Walczak CE, Prigent C, Zhu X, Zhang X, Zheng Y. Aurora A activation in mitosis promoted by BuGZ. The Journal of Cell Biology. PMID 29074706 DOI: 10.1083/Jcb.201706103  0.455
2017 Gigante CM, Dibattista M, Dong FN, Zheng X, Yue S, Young SG, Reisert J, Zheng Y, Zhao H. Lamin B1 is required for mature neuron-specific gene expression during olfactory sensory neuron differentiation. Nature Communications. 8: 15098. PMID 28425486 DOI: 10.1038/Ncomms15098  0.302
2016 Tran JR, Zheng X, Zheng Y. Lamin-B1 contributes to the proper timing of epicardial cell migration and function during embryonic heart development. Molecular Biology of the Cell. PMID 27798236 DOI: 10.1091/Mbc.E16-06-0462  0.411
2016 Chen H, Zheng X, Xiao D, Zheng Y. Age-associated de-repression of retrotransposons in the Drosophila fat body, its potential cause and consequence. Aging Cell. PMID 27072046 DOI: 10.1111/Acel.12465  0.353
2015 Zheng X, Yue S, Chen H, Weber B, Jia J, Zheng Y. Low-Cell-Number Epigenome Profiling Aids the Study of Lens Aging and Hematopoiesis. Cell Reports. PMID 26549448 DOI: 10.1016/J.Celrep.2015.10.004  0.357
2015 Jiang H, He X, Feng D, Zhu X, Zheng Y. RanGTP aids anaphase entry through Ubr5-mediated protein turnover. The Journal of Cell Biology. PMID 26438829 DOI: 10.1083/Jcb.201503122  0.387
2015 Jiang H, Wang S, Huang Y, He X, Cui H, Zhu X, Zheng Y. Phase Transition of Spindle-Associated Protein Regulate Spindle Apparatus Assembly. Cell. PMID 26388440 DOI: 10.1016/J.Cell.2015.08.010  0.5
2015 Oakley BR, Paolillo V, Zheng Y. γ-Tubulin complexes in microtubule nucleation and beyond. Molecular Biology of the Cell. 26: 2957-62. PMID 26316498 DOI: 10.1091/Mbc.E14-11-1514  0.433
2015 Shimi T, Kittisopikul M, Tran J, Goldman AE, Adam SA, Zheng Y, Jaqaman K, Goldman RD. Structural Organization of Nuclear Lamins A, C, B1 and B2 Revealed by Super-Resolution Microscopy. Molecular Biology of the Cell. PMID 26310440 DOI: 10.1091/Mbc.E15-07-0461  0.345
2015 Guo Y, Zheng Y. Lamins position the nuclear pores and centrosomes by modulating dynein. Molecular Biology of the Cell. 26: 3379-89. PMID 26246603 DOI: 10.1091/Mbc.E15-07-0482  0.442
2015 Zheng X, Kim Y, Zheng Y. Identification of lamin B-regulated chromatin regions based on chromatin landscapes. Molecular Biology of the Cell. 26: 2685-97. PMID 25995381 DOI: 10.1091/Mbc.E15-04-0210  0.397
2015 Wan Y, Zheng X, Chen H, Guo Y, Jiang H, He X, Zhu X, Zheng Y. Splicing function of mitotic regulators links R-loop-mediated DNA damage to tumor cell killing. The Journal of Cell Biology. 209: 235-46. PMID 25918225 DOI: 10.1083/Jcb.201409073  0.367
2014 Chen H, Zheng Y. Nuclear lamina builds tissues from the stem cell niche. Fly. 8: 63-7. PMID 25483250 DOI: 10.4161/Fly.28063  0.447
2014 Chen H, Zheng X, Zheng Y. Age-associated loss of lamin-B leads to systemic inflammation and gut hyperplasia. Cell. 159: 829-43. PMID 25417159 DOI: 10.1016/J.Cell.2014.10.028  0.316
2014 Shi C, Channels WE, Zheng Y, Iglesias PA. A computational model for the formation of lamin-B mitotic spindle envelope and matrix. Interface Focus. 4: 20130063. PMID 24904732 DOI: 10.1098/Rsfs.2013.0063  0.431
2014 Guo Y, Kim Y, Shimi T, Goldman RD, Zheng Y. Concentration-dependent lamin assembly and its roles in the localization of other nuclear proteins. Molecular Biology of the Cell. 25: 1287-97. PMID 24523288 DOI: 10.1091/Mbc.E13-11-0644  0.454
2014 Jiang H, He X, Wang S, Jia J, Wan Y, Wang Y, Zeng R, Yates J, Zhu X, Zheng Y. A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targeting. Developmental Cell. 28: 268-81. PMID 24462186 DOI: 10.1016/J.Devcel.2013.12.013  0.445
2014 Liu Z, Vong QP, Liu C, Zheng Y. Borg5 is required for angiogenesis by regulating persistent directional migration of the cardiac microvascular endothelial cells. Molecular Biology of the Cell. 25: 841-51. PMID 24451259 DOI: 10.1091/Mbc.E13-09-0543  0.34
2013 Guo Y, Zheng Y. Sculpting the nucleus with dynamic microtubules. Developmental Cell. 27: 1-2. PMID 24135226 DOI: 10.1016/J.Devcel.2013.09.027  0.434
2013 Wang S, Ketcham SA, Schön A, Goodman B, Wang Y, Yates J, Freire E, Schroer TA, Zheng Y. Nudel/NudE and Lis1 promote dynein and dynactin interaction in the context of spindle morphogenesis. Molecular Biology of the Cell. 24: 3522-33. PMID 24025714 DOI: 10.1091/Mbc.E13-05-0283  0.678
2013 Kim Y, Zheng X, Zheng Y. Proliferation and differentiation of mouse embryonic stem cells lacking all lamins. Cell Research. 23: 1420-3. PMID 23979018 DOI: 10.1038/Cr.2013.118  0.371
2013 Chen H, Chen X, Zheng Y. The nuclear lamina regulates germline stem cell niche organization via modulation of EGFR signaling. Cell Stem Cell. 13: 73-86. PMID 23827710 DOI: 10.1016/J.Stem.2013.05.003  0.398
2013 Zheng Y, Iglesias PA. Nucleating new branches from old. Cell. 152: 669-70. PMID 23415217 DOI: 10.1016/J.Cell.2013.01.040  0.398
2012 Jia J, Zheng X, Hu G, Cui K, Zhang J, Zhang A, Jiang H, Lu B, Yates J, Liu C, Zhao K, Zheng Y. Regulation of pluripotency and self- renewal of ESCs through epigenetic-threshold modulation and mRNA pruning. Cell. 151: 576-89. PMID 23101626 DOI: 10.1016/J.Cell.2012.09.023  0.327
2012 Liu Z, Vong QP, Zheng Y. Using ES cells labeled with GFP for analyzing cell behavior during differentiation. Current Protocols in Stem Cell Biology. Unit1D.8. PMID 22872423 DOI: 10.1002/9780470151808.Sc01D08S22  0.353
2012 McDole K, Zheng Y. Generation and live imaging of an endogenous Cdx2 reporter mouse line. Genesis (New York, N.Y. : 2000). 50: 775-82. PMID 22814996 DOI: 10.1002/Dvg.22049  0.734
2012 Kim Y, McDole K, Zheng Y. The function of lamins in the context of tissue building and maintenance. Nucleus (Austin, Tex.). 3: 256-62. PMID 22614537 DOI: 10.4161/Nucl.20392  0.749
2011 Kim Y, Sharov AA, McDole K, Cheng M, Hao H, Fan CM, Gaiano N, Ko MS, Zheng Y. Mouse B-type lamins are required for proper organogenesis but not by embryonic stem cells. Science (New York, N.Y.). 334: 1706-10. PMID 22116031 DOI: 10.1126/Science.1211222  0.746
2011 Kang J, Goodman B, Zheng Y, Tantin D. Dynamic regulation of Oct1 during mitosis by phosphorylation and ubiquitination. Plos One. 6: e23872. PMID 21897860 DOI: 10.1371/Journal.Pone.0023872  0.64
2011 McDole K, Xiong Y, Iglesias PA, Zheng Y. Lineage mapping the pre-implantation mouse embryo by two-photon microscopy, new insights into the segregation of cell fates. Developmental Biology. 355: 239-49. PMID 21539832 DOI: 10.1016/J.Ydbio.2011.04.024  0.739
2011 Wang S, Zheng Y. Identification of a novel dynein binding domain in nudel essential for spindle pole organization in Xenopus egg extract. The Journal of Biological Chemistry. 286: 587-93. PMID 21056974 DOI: 10.1074/jbc.M110.181578  0.319
2011 Poirier CC, Zheng Y, Iglesias PA. Enclosing, Deformable Membrane Aids in Focusing and Stabilizing the Mitotic Spindle Biophysical Journal. 100: 450a. DOI: 10.1016/J.Bpj.2010.12.2655  0.445
2010 Poirier CC, Zheng Y, Iglesias PA. Mitotic membrane helps to focus and stabilize the mitotic spindle. Biophysical Journal. 99: 3182-90. PMID 21081065 DOI: 10.1016/J.Bpj.2010.09.053  0.408
2010 Goodman B, Channels W, Qiu M, Iglesias P, Yang G, Zheng Y. Lamin B counteracts the kinesin Eg5 to restrain spindle pole separation during spindle assembly. The Journal of Biological Chemistry. 285: 35238-44. PMID 20826821 DOI: 10.1074/Jbc.M110.140749  0.655
2010 Zheng Y. A membranous spindle matrix orchestrates cell division. Nature Reviews. Molecular Cell Biology. 11: 529-35. PMID 20520622 DOI: 10.1038/nrm2919  0.313
2010 Vong QP, Liu Z, Yoo JG, Chen R, Xie W, Sharov AA, Fan CM, Liu C, Ko MS, Zheng Y. A role for borg5 during trophectoderm differentiation. Stem Cells (Dayton, Ohio). 28: 1030-8. PMID 20506138 DOI: 10.1002/Stem.428  0.422
2010 Bembenek JN, White JG, Zheng Y. A role for separase in the regulation of RAB-11-positive vesicles at the cleavage furrow and midbody. Current Biology : Cb. 20: 259-64. PMID 20116245 DOI: 10.1016/J.Cub.2009.12.045  0.397
2009 Liu Z, Zheng Y. A requirement for epsin in mitotic membrane and spindle organization. The Journal of Cell Biology. 186: 473-80. PMID 19704019 DOI: 10.1083/Jcb.200902071  0.36
2009 Ma L, Tsai MY, Wang S, Lu B, Chen R, Iii JR, Zhu X, Zheng Y. Requirement for Nudel and dynein for assembly of the lamin B spindle matrix. Nature Cell Biology. 11: 247-56. PMID 19198602 DOI: 10.1038/ncb1832  0.347
2008 Ducat D, Kawaguchi S, Liu H, Yates JR, Zheng Y. Regulation of microtubule assembly and organization in mitosis by the AAA+ ATPase Pontin. Molecular Biology of the Cell. 19: 3097-110. PMID 18463163 DOI: 10.1091/Mbc.E07-11-1202  0.538
2008 Channels WE, Nédélec FJ, Zheng Y, Iglesias PA. Spatial regulation improves antiparallel microtubule overlap during mitotic spindle assembly. Biophysical Journal. 94: 2598-609. PMID 18096631 DOI: 10.1529/Biophysj.107.117671  0.487
2007 Li HY, Ng WP, Wong CH, Iglesias PA, Zheng Y. Coordination of chromosome alignment and mitotic progression by the chromosome-based Ran signal. Cell Cycle (Georgetown, Tex.). 6: 1886-95. PMID 17671426 DOI: 10.4161/Cc.6.15.4487  0.384
2007 Liu Z, Vong QP, Zheng Y. CLASPing microtubules at the trans-Golgi network. Developmental Cell. 12: 839-40. PMID 17543853 DOI: 10.1016/J.Devcel.2007.05.007  0.427
2006 Zheng Y, Tsai MY. The mitotic spindle matrix: a fibro-membranous lamin connection. Cell Cycle (Georgetown, Tex.). 5: 2345-7. PMID 17102624 DOI: 10.4161/Cc.5.20.3365  0.408
2006 Goodman B, Zheng Y. Mitotic spindle morphogenesis: Ran on the microtubule cytoskeleton and beyond. Biochemical Society Transactions. 34: 716-21. PMID 17052181 DOI: 10.1042/Bst0340716  0.697
2006 Wiese C, Zheng Y. Microtubule nucleation: gamma-tubulin and beyond. Journal of Cell Science. 119: 4143-53. PMID 17038541 DOI: 10.1242/Jcs.03226  0.515
2006 Tsai MY, Wang S, Heidinger JM, Shumaker DK, Adam SA, Goldman RD, Zheng Y. A mitotic lamin B matrix induced by RanGTP required for spindle assembly. Science (New York, N.Y.). 311: 1887-93. PMID 16543417 DOI: 10.1126/Science.1122771  0.449
2006 Tsai MY, Zheng Y. Aurora A Kinase-Coated Beads Function as Microtubule-Organizing Centers and Enhance RanGTP-Induced Spindle Assembly (DOI:10.1016/j.cub.2005.10.054) Current Biology. 16: 1373. DOI: 10.1016/J.Cub.2006.06.028  0.379
2005 Tsai MY, Zheng Y. Aurora A kinase-coated beads function as microtubule-organizing centers and enhance RanGTP-induced spindle assembly. Current Biology : Cb. 15: 2156-63. PMID 16332542 DOI: 10.1016/J.Cub.2005.10.054  0.418
2005 Vong QP, Cao K, Li HY, Iglesias PA, Zheng Y. Chromosome alignment and segregation regulated by ubiquitination of survivin. Science (New York, N.Y.). 310: 1499-504. PMID 16322459 DOI: 10.1126/Science.1120160  0.595
2004 Ducat D, Zheng Y. Aurora kinases in spindle assembly and chromosome segregation. Experimental Cell Research. 301: 60-7. PMID 15501446 DOI: 10.1016/J.Yexcr.2004.08.016  0.4
2004 Zheng Y. G protein control of microtubule assembly. Annual Review of Cell and Developmental Biology. 20: 867-94. PMID 15473863 DOI: 10.1146/Annurev.Cellbio.20.012103.094648  0.499
2004 Li HY, Zheng Y. The production and localization of GTP-bound ran in mitotic mammalian tissue culture cells. Cell Cycle (Georgetown, Tex.). 3: 993-5. PMID 15254395 DOI: 10.4161/Cc.3.8.1059  0.369
2004 Li HY, Zheng Y. Phosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cells. Genes & Development. 18: 512-27. PMID 15014043 DOI: 10.1101/Gad.1177304  0.432
2004 Cao K, Zheng Y. The Cdc48/p97-Ufd1-Npl4 complex: its potential role in coordinating cellular morphogenesis during the M-G1 transition. Cell Cycle (Georgetown, Tex.). 3: 422-4. PMID 15004522 DOI: 10.4161/Cc.3.4.814  0.587
2004 Kawaguchi S, Zheng Y. Characterization of a Drosophila centrosome protein CP309 that shares homology with Kendrin and CG-NAP. Molecular Biology of the Cell. 15: 37-45. PMID 14565985 DOI: 10.1091/Mbc.E03-03-0191  0.531
2004 Ems-McClung SC, Zheng Y, Walczak CE. Importin alpha/beta and Ran-GTP regulate XCTK2 microtubule binding through a bipartite nuclear localization signal. Molecular Biology of the Cell. 15: 46-57. PMID 13679510 DOI: 10.1091/Mbc.E03-07-0454  0.376
2003 Cao K, Nakajima R, Meyer HH, Zheng Y. The AAA-ATPase Cdc48/p97 regulates spindle disassembly at the end of mitosis. Cell. 115: 355-67. PMID 14636562 DOI: 10.1016/S0092-8674(03)00815-8  0.642
2003 Li HY, Cao K, Zheng Y. Ran in the spindle checkpoint: a new function for a versatile GTPase. Trends in Cell Biology. 13: 553-7. PMID 14573347 DOI: 10.1016/J.Tcb.2003.09.003  0.604
2003 Gunawardane RN, Martin OC, Zheng Y. Characterization of a new gammaTuRC subunit with WD repeats. Molecular Biology of the Cell. 14: 1017-26. PMID 12631720 DOI: 10.1091/Mbc.E02-01-0034  0.757
2003 Li HY, Wirtz D, Zheng Y. A mechanism of coupling RCC1 mobility to RanGTP production on the chromatin in vivo. The Journal of Cell Biology. 160: 635-44. PMID 12604592 DOI: 10.1083/Jcb.200211004  0.385
2003 Tsai MY, Wiese C, Cao K, Martin O, Donovan P, Ruderman J, Prigent C, Zheng Y. A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly. Nature Cell Biology. 5: 242-8. PMID 12577065 DOI: 10.1038/Ncb936  0.614
2002 Lizarraga SB, Zheng Y, Wilde AR. Characterization of the effects of RanGTP on the microtubule cytoskeleton. Methods in Molecular Biology (Clifton, N.J.). 189: 247-60. PMID 12094591 DOI: 10.1385/1-59259-281-3:247  0.733
2001 Gunawardane RN, Zheng Y, Oegema K, Wiese C. Purification and reconstitution of Drosophila gamma-tubulin complexes. Methods in Cell Biology. 67: 1-25. PMID 11550462 DOI: 10.1016/S0091-679X(01)67002-X  0.739
2001 Wilde A, Lizarraga SB, Zhang L, Wiese C, Gliksman NR, Walczak CE, Zheng Y. Ran stimulates spindle assembly by altering microtubule dynamics and the balance of motor activities. Nature Cell Biology. 3: 221-7. PMID 11231570 DOI: 10.1038/35060000  0.735
2001 Wiese C, Wilde A, Moore MS, Adam SA, Merdes A, Zheng Y. Role of importin-beta in coupling Ran to downstream targets in microtubule assembly. Science (New York, N.Y.). 291: 653-6. PMID 11229403 DOI: 10.1126/Science.1057661  0.42
2000 Zhang L, Keating TJ, Wilde A, Borisy GG, Zheng Y. The role of Xgrip210 in gamma-tubulin ring complex assembly and centrosome recruitment. The Journal of Cell Biology. 151: 1525-36. PMID 11134080 DOI: 10.1083/Jcb.151.7.1525  0.506
2000 Gunawardane RN, Martin OC, Cao K, Zhang L, Dej K, Iwamatsu A, Zheng Y. Characterization and reconstitution of Drosophila gamma-tubulin ring complex subunits. The Journal of Cell Biology. 151: 1513-24. PMID 11134079 DOI: 10.1083/Jcb.151.7.1513  0.779
2000 Gunawardane RN, Lizarraga SB, Wiese C, Wilde A, Zheng Y. gamma-Tubulin complexes and their role in microtubule nucleation. Current Topics in Developmental Biology. 49: 55-73. PMID 11005014 DOI: 10.1016/S0070-2153(99)49004-0  0.789
2000 Wiese C, Zheng Y. A new function for the γ-tubulin ring complex as a microtubule minus-end cap Nature Cell Biology. 2: 358-364. PMID 10854327 DOI: 10.1038/35014051  0.474
1999 Wilde A, Zheng Y. Stimulation of microtubule aster formation and spindle assembly by the small GTPase Ran. Science (New York, N.Y.). 284: 1359-62. PMID 10334991 DOI: 10.1126/Science.284.5418.1359  0.501
1999 Wiese C, Zheng Y. γ-tubulin complexes and their interaction with microtubule-organizing centers Current Opinion in Structural Biology. 9: 250-259. PMID 10322210 DOI: 10.1016/S0959-440X(99)80035-9  0.48
1999 Oegema K, Wiese C, Martin OC, Milligan RA, Iwamatsu A, Mitchison TJ, Zheng Y. Characterization of two related Drosophila gamma-tubulin complexes that differ in their ability to nucleate microtubules. The Journal of Cell Biology. 144: 721-33. PMID 10037793 DOI: 10.1083/Jcb.144.4.721  0.463
1998 Zheng Y, Wong ML, Alberts B, Mitchison T. [19] Purification and assay of γ tubulin ring complex Methods in Enzymology. 298: 218-228. PMID 9751884 DOI: 10.1016/S0076-6879(98)98021-1  0.325
1998 Moritz M, Zheng Y, Alberts BM, Oegema K. Recruitment of the γ-tubulin ring complex to Drosophila salt-stripped centrosome scaffolds Journal of Cell Biology. 142: 775-786. PMID 9700165 DOI: 10.1083/Jcb.142.3.775  0.473
1998 Martin OC, Gunawardane RN, Iwamatsu A, Zheng Y. Xgrip109: a gamma tubulin-associated protein with an essential role in gamma tubulin ring complex (gammaTuRC) assembly and centrosome function. The Journal of Cell Biology. 141: 675-87. PMID 9566968 DOI: 10.1083/Jcb.141.3.675  0.765
1997 Wilson PG, Zheng Y, Oakley CE, Oakley BR, Borisy GG, Fuller MT. Differential expression of two gamma-tubulin isoforms during gametogenesis and development in Drosophila. Developmental Biology. 184: 207-21. PMID 9133431 DOI: 10.1006/Dbio.1997.8545  0.396
1991 Zheng Y, Jung MK, Oakley BR. Gamma-tubulin is present in Drosophila melanogaster and Homo sapiens and is associated with the centrosome. Cell. 65: 817-23. PMID 1904010 DOI: 10.1016/0092-8674(91)90389-G  0.482
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