| Year | Citation | Score | |||
|---|---|---|---|---|---|
| 2023 | Chui JS, Izuel-Idoype T, Qualizza A, de Almeida RP, Piessens L, van der Veer BK, Vanmarcke G, Malesa A, Athanasouli P, Boon R, Vriens J, van Grunsven L, Koh KP, Verfaillie CM, Lluis F. Osmolar Modulation Drives Reversible Cell Cycle Exit and Human Pluripotent Cell Differentiation via NF-κВ and WNT Signaling. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2307554. PMID 38037844 DOI: 10.1002/advs.202307554 | 0.554 | |||
| 2023 | Linder SJ, Bernasocchi T, Martínez-Pastor B, Sullivan KD, Galbraith MD, Lewis CA, Ferrer CM, Boon R, Silveira GG, Cho HM, Vidoudez C, Shroff S, Oliveira-Costa JP, Ross KN, Massri R, et al. Inhibition of the proline metabolism rate-limiting enzyme P5CS allows proliferation of glutamine-restricted cancer cells. Nature Metabolism. PMID 37957387 DOI: 10.1038/s42255-023-00919-3 | 0.32 | |||
| 2023 | Vanmarcke G, Sai-Hong Chui J, Cooreman A, De Vos K, Cleuren L, Van Rossom R, García-Llorens G, Izuel Idoype T, Boon R, Kumar Gautam M, Castell JV, Annaert P, Lluis F, Verfaillie CM. Automated generation of hiPSC-derived hepatic progeny by cost-efficient compounds. Stem Cells (Dayton, Ohio). PMID 37616601 DOI: 10.1093/stmcls/sxad065 | 0.505 | |||
| 2022 | Tricot T, Thibaut HJ, Abbasi K, Boon R, Helsen N, Kumar M, Neyts J, Verfaillie C. Metabolically Improved Stem Cell Derived Hepatocyte-Like Cells Support HBV Life Cycle and Are a Promising Tool for HBV Studies and Antiviral Drug Screenings. Biomedicines. 10. PMID 35203482 DOI: 10.3390/biomedicines10020268 | 0.496 | |||
| 2022 | Moreno-Torres M, Kumar M, García-Llorens G, Quintás G, Tricot T, Boon R, Tolosa L, Toprakhisar B, Chesnais F, Verfaillie C, Castell JV. A Novel UPLC-MS Metabolomic Analysis-Based Strategy to Monitor the Course and Extent of iPSC Differentiation to Hepatocytes. Journal of Proteome Research. PMID 34982937 DOI: 10.1021/acs.jproteome.1c00779 | 0.554 | |||
| 2021 | Kumar M, Toprakhisar B, Van Haele M, Antoranz A, Boon R, Chesnais F, De Smedt J, Tricot T, Idoype TI, Canella M, Tilliole P, De Boeck J, Bajaj M, Ranga A, Bosisio FM, et al. A fully defined matrix to support a pluripotent stem cell derived multi-cell-liver steatohepatitis and fibrosis model. Biomaterials. 276: 121006. PMID 34304139 DOI: 10.1016/j.biomaterials.2021.121006 | 0.537 | |||
| 2021 | Fazal R, Boeynaems S, Swijsen A, De Decker M, Fumagalli L, Moisse M, Vanneste J, Guo W, Boon R, Vercruysse T, Eggermont K, Swinnen B, Beckers J, Pakravan D, Vandoorne T, et al. HDAC6 inhibition restores TDP-43 pathology and axonal transport defects in human motor neurons with TARDBP mutations. The Embo Journal. e106177. PMID 33694180 DOI: 10.15252/embj.2020106177 | 0.426 | |||
| 2021 | Ter Braak B, Niemeijer M, Boon R, Parmentier C, Baze A, Richert L, Huppelschoten S, Wink S, Verfaillie C, van de Water B. Systematic transcriptome-based comparison of cellular adaptive stress response activation networks in hepatic stem cell-derived progeny and primary human hepatocytes. Toxicology in Vitro : An International Journal Published in Association With Bibra. 73: 105107. PMID 33545341 DOI: 10.1016/j.tiv.2021.105107 | 0.509 | |||
| 2021 | De Smedt J, van Os EA, Talon I, Ghosh S, Toprakhisar B, Furtado Madeiro Da Costa R, Zaunz S, Vazquez MA, Boon R, Baatsen P, Smout A, Verhulst S, van Grunsven LA, Verfaillie CM. PU.1 drives specification of pluripotent stem cell-derived endothelial cells to LSEC-like cells. Cell Death & Disease. 12: 84. PMID 33446637 DOI: 10.1038/s41419-020-03356-2 | 0.574 | |||
| 2020 | Boon R, Kumar M, Tricot T, Elia I, Ordovas L, Jacobs F, One J, De Smedt J, Eelen G, Bird M, Roelandt P, Doglioni G, Vriens K, Rossi M, Vazquez MA, et al. Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines. Nature Communications. 11: 1393. PMID 32170132 DOI: 10.1038/S41467-020-15058-6 | 0.613 | |||
| 2019 | Elia I, Rossi M, Stegen S, Broekaert D, Doglioni G, van Gorsel M, Boon R, Escalona-Noguero C, Torrekens S, Verfaillie C, Verbeken E, Carmeliet G, Fendt SM. Breast cancer cells rely on environmental pyruvate to shape the metastatic niche. Nature. PMID 30814728 DOI: 10.1038/S41586-019-0977-X | 0.503 | |||
| 2019 | Vriens K, Christen S, Parik S, Broekaert D, Yoshinaga K, Talebi A, Dehairs J, Escalona-Noguero C, Schmieder R, Cornfield T, Charlton C, Romero-Pérez L, Rossi M, Rinaldi G, Orth MF, ... Boon R, et al. Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity. Nature. PMID 30728499 DOI: 10.1038/S41586-019-0904-1 | 0.497 | |||
| 2018 | Claes C, Van Den Daele J, Boon R, Schouteden S, Colombo A, Monasor LS, Fiers M, Ordovás L, Nami F, Bohrmann B, Tahirovic S, De Strooper B, Verfaillie CM. Human stem cell-derived monocytes and microglia-like cells reveal impaired amyloid plaque clearance upon heterozygous or homozygous loss of TREM2. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30442540 DOI: 10.1016/J.Jalz.2018.09.006 | 0.564 | |||
| 2018 | Coll M, Perea L, Boon R, Leite SB, Vallverdú J, Mannaerts I, Smout A, El Taghdouini A, Blaya D, Rodrigo-Torres D, Graupera I, Aguilar-Bravo B, Chesne C, Najimi M, Sokal E, et al. Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis. Cell Stem Cell. 23: 101-113.e7. PMID 30049452 DOI: 10.1016/J.Stem.2018.05.027 | 0.631 | |||
| 2018 | Ordovás L, Boon R, Pistoni M, Chen Y, Wolfs E, Guo W, Sambathkumar R, Bobis-Wozowicz S, Helsen N, Vanhove J, Berckmans P, Cai Q, Vanuytsel K, Eggermont K, Vanslembrouck V, et al. Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition. Stem Cell Reports. 10: 673. PMID 29444475 DOI: 10.1016/j.stemcr.2018.01.034 | 0.431 | |||
| 2018 | García-León JA, Kumar M, Boon R, Chau D, One J, Wolfs E, Eggermont K, Berckmans P, Gunhanlar N, de Vrij F, Lendemeijer B, Pavie B, Corthout N, Kushner SA, Dávila JC, et al. SOX10 Single Transcription Factor-Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells. Stem Cell Reports. PMID 29337119 DOI: 10.1016/J.Stemcr.2017.12.014 | 0.543 | |||
| 2018 | Kumar M, Chesnais F, Boon R, Krebs A, Curtiss C, Toprakhisar B, Jacobs F, Schmidt B, Leist M, Verfaillie C. Creation of a stable and highly functional pluripotent stem cell derived hepatocyte model for drug metabolisation and toxicity screening Toxicology Letters. 295: S78. DOI: 10.1016/j.toxlet.2018.06.542 | 0.518 | |||
| 2017 | Pistoni M, Helsen N, Vanhove J, Boon R, Xu Z, Ordovas L, Verfaillie CM. Dynamic regulation of EZH2 from HPSc to hepatocyte-like cell fate. Plos One. 12: e0186884. PMID 29091973 DOI: 10.1371/Journal.Pone.0186884 | 0.595 | |||
| 2017 | Guo W, Naujock M, Fumagalli L, Vandoorne T, Baatsen P, Boon R, Ordovás L, Patel A, Welters M, Vanwelden T, Geens N, Tricot T, Benoy V, Steyaert J, Lefebvre-Omar C, et al. HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients. Nature Communications. 8: 861. PMID 29021520 DOI: 10.1038/S41467-017-00911-Y | 0.503 | |||
| 2017 | Elia I, Broekaert D, Christen S, Boon R, Radaelli E, Orth MF, Verfaillie C, Grünewald TGP, Fendt SM. Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells. Nature Communications. 8: 15267. PMID 28492237 DOI: 10.1038/Ncomms15267 | 0.515 | |||
| 2016 | Ordovás L, Boon R, Pistoni M, Chen Y, Sambathkumar R, Helsen N, Vanhove J, Berckmans P, Cai Q, Vanuytsel K, Raitano S, Verfaillie CM. Rapid and Efficient Generation of Recombinant Human Pluripotent Stem Cells by Recombinase-mediated Cassette Exchange in the AAVS1 Locus. Journal of Visualized Experiments : Jove. PMID 27911376 DOI: 10.3791/54718 | 0.544 | |||
| 2016 | Lorendeau D, Rinaldi G, Boon R, Spincemaille P, Metzger K, Jäger C, Christen S, Dong X, Kuenen S, Voordeckers K, Verstreken P, Cassiman D, Vermeersch P, Verfaillie C, Hiller K, et al. Dual loss of succinate dehydrogenase (SDH) and complex I activity is necessary to recapitulate the metabolic phenotype of SDH mutant tumors. Metabolic Engineering. PMID 27847310 DOI: 10.1016/J.Ymben.2016.11.005 | 0.457 | |||
| 2016 | Vanhove J, Pistoni M, Welters M, Eggermont K, Vanslembrouck V, Helsen N, Boon R, Najimi M, Sokal E, Collas P, Voncken JW, Verfaillie CM. H3K27me3 Does Not Orchestrate the Expression of Lineage-Specific Markers in hESC-Derived Hepatocytes In Vitro. Stem Cell Reports. PMID 27477635 DOI: 10.1016/J.Stemcr.2016.06.013 | 0.578 | |||
| 2016 | Lange C, Turrero Garcia M, Decimo I, Bifari F, Eelen G, Quaegebeur A, Boon R, Zhao H, Boeckx B, Chang J, Wu C, Le Noble F, Lambrechts D, Dewerchin M, Kuo CJ, et al. Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis. The Embo Journal. PMID 26856890 DOI: 10.15252/Embj.201592372 | 0.412 | |||
| 2016 | Coll M, Perea L, Boon R, Vallverdú J, Rodrigo-Torres D, Blaya D, Llopis M, Graupera I, Aguilar B, Verfaillie C, Ginès P, Sancho-Bru P. Directed Differentiation of IPS Cells to Hepatic Stellate Cells Journal of Hepatology. 64. DOI: 10.1016/S0168-8278(16)01367-2 | 0.585 | |||
| 2015 | Helsen N, Debing Y, Paeshuyse J, Dallmeier K, Boon R, Coll M, Sancho-Bru P, Claes C, Neyts J, Verfaillie CM. Stem cell-derived hepatocytes: A novel model for hepatitis E virus replication. Journal of Hepatology. PMID 26626494 DOI: 10.1016/J.Jhep.2015.11.013 | 0.534 | |||
| 2015 | Manesia JK, Xu Z, Broekaert D, Boon R, van Vliet A, Eelen G, Vanwelden T, Stegen S, Van Gastel N, Pascual-Montano A, Maria-Fendt S, Carmeliet G, Carmeliet P, Khurana S, Verfaillie CM. Highly proliferative primitive fetal liver hematopoietic stem cells are fueled by oxidative metabolic pathways. Stem Cell Research. 15: 715-721. PMID 26599326 DOI: 10.1016/J.Scr.2015.11.001 | 0.54 | |||
| 2015 | Ordovás L, Boon R, Pistoni M, Chen Y, Wolfs E, Guo W, Sambathkumar R, Bobis-Wozowicz S, Helsen N, Vanhove J, Berckmans P, Cai Q, Vanuytsel K, Eggermont K, Vanslembrouck V, et al. Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition. Stem Cell Reports. PMID 26455413 DOI: 10.1016/J.Stemcr.2015.09.004 | 0.578 | |||
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